
Alberto De Vitta, Thiago Paulo Frascareli Bento, Guilherme Porfírio Cornélio, Priscila Daniele de Oliveira Perrucini, Lílian Assunção Felippe, Marta Helena Souza De Conti,
Low back pain (LBP) is a common complaint among children and adolescents and can negatively impact their physical and mental health. Although previous studies investigating the incidence of low back pain (LBP) in children and adolescents have been performed in high income countries, it is unclear whether countries such as Brazil would show similar incidence rates.To determine the incidence and to identify predictors of new episodes of LBP in high school students.This is a 1-year longitudinal study ...
Tópico(s): Injury Epidemiology and Prevention
2021 - Elsevier BV | Brazilian Journal of Physical Therapy

Thiago Paulo Frascareli Bento, Caio Vitor dos Santos Genebra, Nicoly Machado Maciel, Guilherme Porfírio Cornélio, Sandra Fiorelli Almeida Penteado Simeão, Alberto De Vitta,
To compare men and women with low back pain and identify the prevalence and some of its associated factors in a population-based sample of adults aged 20 and over a seven day period. Cross-sectional study based on a population survey. 600 individuals were interviewed on the following: (1) characteristics of the participants (i.e. demographic, socioeconomic, and labor aspects); (2) physical activity level (IPAQ); (3) musculoskeletal symptoms (Nordic Questionnaire). Descriptive, bivariate, and Poisson regression ...
Tópico(s): Occupational health in dentistry
2019 - Elsevier BV | Brazilian Journal of Physical Therapy

Thiago Paulo Frascareli Bento, Guilherme Porfírio Cornélio, Priscila Daniele de Oliveira Perrucini, Sandra Fiorelli Almeida Penteado Simeão, Marta Helena Souza De Conti, Alberto De Vitta,
To determine the prevalence of low back pain and to analyze the association with the individual, sociodemographic variables, electronic devices, habitual practice of physical activity, and mental health problems.Cross-sectional study with 1,628 students in public schools in the city of Bauru, SP, Brazil. The following data were collected: 1. demographic and socioeconomic aspects; 2. Use of electronic devices; 3. habitual physical activity level (Baecke); 3. mental health (SDQ). 4. low back pain (Nordic ...
Tópico(s): Ergonomics and Musculoskeletal Disorders
2019 - Elsevier BV | Jornal de Pediatria

Caio Vitor dos Santos Genebra, Nicoly Machado Maciel, Thiago Paulo Frascareli Bento, Sandra Fiorelli Almeida Penteado Simeão, Alberto De Vitta,
Tópico(s): Spine and Intervertebral Disc Pathology
2017 - Elsevier BV | Brazilian Journal of Physical Therapy

Alberto De Vitta, José Paulo Candido, Thiago Paulo Frascareli Bento, Guilherme Porfírio Cornélio, Priscila Daniele de Oliveira Perrucini, Júlio Alberto Agante Fernandes, Wagner Luiz Ramos,
INTRODUÇÃO: A dor cervical é uma condição musculoesquelética com alta prevalência que pode afetar os aspectos físicos, sociais e psicológicos dos indivíduos, contribuindo para o aumento de custos na sociedade e nos negócios. OBJETIVOS: Determinar a prevalência de dor cervical e analisar a associação com variáveis sociodemográficas e dispositivos eletrônicos. MÉTODOS: Foi realizado um estudo observacional transversal com uma amostra de 1143 universitários, que responderam ao questionário sobre aspectos ...
Tópico(s): Healthcare during COVID-19 Pandemic
2020 - | Ciência em Movimento

Rocha dos Santos Mathias Thiago, Paulo Moretzsohn de Mello Pedro, Flavia Camporese Srvulo Eliana,
A large amount of agro-industrial waste is produced annually around the world from the beneficiated agricultural products or in food industrialization. The disposal of these residues in the environment results in a lot of inconvenience to the ecosystem, due to its significant nutritional value and high concentration of organic compounds that confers a high biochemical oxygen demand to the waste’s degradation. In this context, brewing industry is among these activities, which includes in its production ...
Tópico(s): Agriculture Sustainability and Environmental Impact
2014 - Academic Journals | Journal of Brewing and Distilling
Rafael Geraldeli Rossi, Alneu de Andrade Lopes, Thiago de Paulo Faleiros, Solange Oliveira Rezende,
Tópico(s): Advanced Text Analysis Techniques
2014 - Springer Science+Business Media | Journal of Computer Science and Technology

Otávio Berwanger, Alexandre Biasi Cavalcanti, Amanda M.G. Sousa, Anna Maria Buehler, Helio José Castello-Júnior, Marcelo J. C. Cantarelli, José Armando Mangione, Ricardo Reinaldo Bergo, Luiz Eduardo Koenig São Thiago, Paulo Márcio Sousa Nunes, Paulo Antônio Marra da Motta, Alessandra A. Kodama, Elivane da Silva Victor, Vitor Oliveira Carvalho, J. Eduardo Sousa,
Background— Diabetes mellitus represents an independent risk factor for contrast-induced acute kidney injury. We report the results of a prespecified substudy of patients with diabetes mellitus included in the Acetylcysteine for Contrast-Induced Nephropathy Trial (ACT), the largest randomized study evaluating the effects of acetylcysteine for the prevention of contrast-induced acute kidney injury conducted to date. Methods and Results— From the 2308 patients included in the ACT, 1395 had diabetes ...
Tópico(s): Renal and Vascular Pathologies
2013 - Lippincott Williams & Wilkins | Circulation Cardiovascular Interventions

Lilian Berton, Thiago de Paulo Faleiros, Alan Valejo, Jorge Valverde-Rebaza, Alneu de Andrade Lopes,
Graph-based semi-supervised learning (SSL) provides a powerful framework for the modeling of manifold structures in high-dimensional spaces. Additionally, graph representation is effective for the propagation of the few initial labels existing in training data. Graph-based SSL requires robust graphs as input for an accurate data mining task, such as classification. In contrast to most graph construction methods, which ignore the labeled instances available in SSL scenarios, a previous study proposed ...
Tópico(s): Machine Learning and Data Classification
2016 - Elsevier BV | Neurocomputing
... P. Shock, Guilherme Z. Mongeló, Fernando O. Almeida, Thiago Kater, Paulo E. De Oliveira, Eduardo G. Neves, John P. ...
Tópico(s): Environmental and Cultural Studies in Latin America and Beyond
2009 - University of Chicago Press | Current Anthropology

Thiago Paulo Frascareli Bento, Caio Vitor dos Santos Genebra, Guilherme Porfírio Cornélio, Rangel Dal Bello Biancon, Sandra Fiorelli Almeida Penteado Simeão, Alberto De Vitta,
ABSTRACT Musculoskeletal pain in the shoulder is considered one of the most prevalent causes of pain and disability in adults. To verify the prevalence of shoulder pain and correlated factors in adults aged 20 years or older in cross-sectional study with 600 individuals interviewed through questionnaires: (1) participants characterization; (2) level of physical activity; (3) reported morbidities; and (4) musculoskeletal symptoms. Descriptive, bivariate, and Poisson regression analyses were performed. ...
Tópico(s): Occupational health in dentistry
2019 - UNIVERSIDADE DE SÃO PAULO | Fisioterapia e Pesquisa

Alberto De Vitta, Thiago Paulo Frascareli Bento, Priscila Daniele de Oliveira Perrucini, Lílian Assunção Felippe, Regina Célia Poli‐Frederico, Sérgio M. Borghi,
Neck pain is a major public health problem.The aim of the present study was to determine the prevalence of neck pain among high school students and to analyze associations with sociodemographic variables, use of electronic devices, habitual physical activity practices and mental health problems.Cross-sectional epidemiological study on a sample of high school students in the city of Bauru, São Paulo, Brazil.Participants were selected through cluster sampling in two stages and data were collected ...
Tópico(s): Occupational Health and Burnout
2021 - Medical Association of São Paulo | Sao Paulo Medical Journal

Patrícia da Silva Figueirêdo Ferreira, Patrícia Constantino Motta, Tayane Crispim de Souza, Thiago Paulo da Silva, Juliana Ferreira de Oliveira, Ana Sílvia Pereira Santos,
Sendo o saneamento básico um serviço de infraestrutura fundamental na promoção da saúde pública em uma localidade, este trabalho foi realizado com o objetivo de relacionar os impactos na saúde da população e os custos gerados, devido à ineficiência do serviço de saneamento ambiental no Brasil. Destacam-se para a elaboração desse estudo duas etapas: 1) análise do número de casos, por região geográfica, de 10 dentre as principais doenças de veiculação hídrica no período de 2001 a 2010; e 2) comparação ...
Tópico(s): Child Nutrition and Water Access
2016 - UNIVERSIDADE DO ESTADO DO RIO DE JANEIRO | Revista Internacional de Ciências

Isabela M. Gonzaga, Sheila Coelho Soares-Lima, Paulo Thiago Souza de Santos, Tânia Cristina Moita Blanco, Bruno Souza Bianchi de Reis, Danielle Carvalho Quintella, Ivanir Martins de Oliveira, Paulo Antônio Silvestre de Faria, Cleber Dario Pinto Kruel, Nelson Adami Andreollo, T.A. Simão, Luís Felipe Ribeiro Pinto,
A bstract Background Esophageal squamous cell carcinoma (ESCC) shows a 5-year survival rate below 10%, demonstrating the urgency in improving its treatment. Alterations in epidermal growth factor receptors are closely related to malignancy transformation in a number of tumors and recent successful targeted therapies have been directed to these molecules. Therefore, in this study, we analyzed the expression of EGFR and HER2 and evaluated EGFR mutation profile as well as the presence of mutations in ...
Tópico(s): Glycosylation and Glycoproteins Research
2012 - BioMed Central | BMC Cancer

Tatiana de Almeida Simão, Paulo Thiago de Souza-Santos, Diego Sá Leal de Oliveira, Vagner Gonçalves Bernardo, Sheila Coelho Soares-Lima, Davy Rapozo, Cleber D.P. Kruel, Paulo Antônio Silvestre de Faria, Luís Felipe Ribeiro Pinto, Rodolpho Mattos Albano,
Esophageal squamous cell carcinoma (ESCC) is highly fatal due to late diagnosis and inefficient treatment. Early disease detection could improve diagnosis and patient survival. Esophageal squamous epithelial cells express SPRR3, a member of the small proline-rich protein family, which is downregulated in ESCC. Therefore, SPRR3 expression may be used as a biomarker to follow the transition from healthy mucosa to ESCC. Both SPRR3 mRNA splice variants, v1 and v2, were evaluated by real time PCR in tumor ...
Tópico(s): Cancer-related gene regulation
2011 - Elsevier BV | Experimental and Molecular Pathology

Thiago Paulo Frascareli Bento, Guilherme Porfírio Cornélio, Priscila Daniele de Oliveira Perrucini, Sandra Fiorelli Almeida Penteado Simeão, Marta Helena Souza De Conti, Alberto De Vitta,
To determine the prevalence of low back pain and to analyze the association with the individual, sociodemographic variables, electronic devices, habitual practice of physical activity, and mental health problems. Cross‐sectional study with 1,628 students in public schools in the city of Bauru, SP, Brazil. The following data were collected: 1. demographic and socioeconomic aspects; 2. Use of electronic devices; 3. habitual physical activity level (Baecke); 3. mental health (SDQ). 4. low back pain (Nordic ...
Tópico(s): Ergonomics and Musculoskeletal Disorders
2020 - Elsevier BV | Jornal de Pediatria (Versão em Português)
Thiago Piacentini, Paulo Vasconcelos, K. A. Farley,
Urucum is one of the youngest banded iron-formations (BIFs) yet its exact age remains uncertain. 40Ar/39Ar geochronology on late-diagenetic to early metamorphic cryptomelane from the Urucum sequence reveals a minimum depositional age of 587 ± 7 Ma. Metamorphic braunite age spectra yield flat segments defining apparent ages of 547 ± 3 Ma to 513 ± 4 Ma, interpreted as recrystallization or cooling ages. Metamorphic muscovite grains from a meta-arkose interbedded with the BIF yield reproducible plateau ages ...
Tópico(s): Geochemistry and Elemental Analysis
2013 - Elsevier BV | Precambrian Research

Daniel G. Costa, João Paulo Just Peixoto, Thiago C. Jesus, Paulo Portugal, Francisco Vasques, Elivelton O. Rangel, Maycon Peixoto,
The rapid urbanization process in the last hundred of years has deeply changed the way we live and interact with each other. As most people now live in urban areas, cities are experiencing growing demands for more efficient and sustainable public services that may improve the perceived quality of life, specially with the anticipated impacts of climatic changes. In this already complex scenario with increasingly overcrowded urban areas, different types of emergency situations may happen anywhere ...
Tópico(s): Traffic Prediction and Management Techniques
2022 - Institute of Electrical and Electronics Engineers | IEEE Access

Raquel Rodrigues Barbieri, Yixi Xu, Lucy Setian, Paulo Thiago de Souza-Santos, Anusua Trivedi, Jim Cristofono, Ricardo Bhering, Kevin White, Anna Maria Sales, Geralyn Miller, José A. C. Nery, Michael Sharman, Richard Bumann, Shun Zhang, Mohamad Goldust, Euzenir Nunes Sarno, Fareed Mirza, Arielle Cavaliero, Sander W. Timmer, Elena Bonfiglioli, Cairns Smith, David M. Scollard, Alexander A. Navarini, Ann Aerts, Juan Lavista Ferres, Milton Ozório Moraes,
Leprosy is an infectious disease that mostly affects underserved populations. Although it has been largely eliminated, still about 200'000 new patients are diagnosed annually. In the absence of a diagnostic test, clinical diagnosis is often delayed, potentially leading to irreversible neurological damage and its resulting stigma, as well as continued transmission. Accelerating diagnosis could significantly contribute to advancing global leprosy elimination. Digital and Artificial Intelligence (AI) ...
Tópico(s): Dermatological diseases and infestations
2022 - Elsevier BV | The Lancet Regional Health - Americas
David Danko, Daniela Bezdan, Evan E. Afshin, Sofia Ahsanuddin, Chandrima Bhattacharya, Daniel Butler, Kern Rei Chng, Daisy Donnellan, Jochen Hecht, Katelyn Jackson, Katerina Kuchin, Mikhail Karasikov, Abigail Lyons, Lauren Mak, Dmitry Meleshko, Harun Mustafa, Beth Mutai, Russell Y. Neches, Amanda Hui Qi Ng, Olga Nikolayeva, Tatyana Nikolayeva, Eileen Png, Krista Ryon, Jorge L. Sánchez, Heba Shaaban, Maria A. Sierra, Dominique Thomas, Ben Young, Omar O. Abudayyeh, Josue Alicea, Malay Bhattacharyya, Ran Blekhman, Eduardo Castro‐Nallar, A Cañas, Aspassia D. Chatziefthimiou, Robert W. Crawford, Francesca De Filippis, Youping Deng, Christelle Desnues, Emmanuel Dias‐Neto, Marius Dybwad, Eran Elhaik, Danilo Ercolini, Alina Frolova, Dennis Gankin, Jonathan S. Gootenberg, Alexandra Gráf, David C. Green, Iman Hajirasouliha, Jaden J. A. Hastings, Mark Hernandez, Gregorio Iraola, Soojin Jang, André Kahles, Frank J. Kelly, Kaymisha Knights, Nikos C. Kyrpides, Paweł P. Łabaj, Patrick K. H. Lee, Marcus H. Y. Leung, Per O. Ljungdahl, Gabriella Mason-Buck, Ken McGrath, Cem Meydan, Emmanuel F. Mongodin, Milton Ozório Moraes, Niranjan Nagarajan, Marina Nieto‐Caballero, Houtan Noushmehr, Manuela Oliveira, Stephan Ossowski, Olayinka Osuolale, Orhan Özcan, David Páez-Espino, Nicolás Rascovan, Hugues Richard, Gunnar Rätsch, Lynn M. Schriml, Torsten Semmler, Uğur Sezerman, Leming Shi, Tieliu Shi, Rania Siam, Le Huu Song, Haruo Suzuki, Denise Syndercombe Court, Scott Tighe, Xinzhao Tong, Klas I. Udekwu, Juan A. Ugalde, Brandon Valentine, Dimitar Vassilev, Elena Vayndorf, Thirumalaisamy P. Velavan, Jun Wu, María Mercedes Zambrano, Jifeng Zhu, Sibo Zhu, Christopher E. Mason, Nurul Akmaryanti Abdullah, Marcos Abraao, Ait-hamlat Adel, Muhammad Afaq, Faisal Alquaddoomi, Ireen Alam, Gabriela E. Albuquerque, Alex Alexiev, K. Mohammed Ali, Lucia Elena Alvarado-Arnez, Sarh Aly, Jennifer Amachee, María Galli de Amorim, Majelia Ampadu, Muhammad Al-Fath Amran, Nala An, Watson Andrew, Harilanto Andrianjakarivony, Michael Angelov, Verónica Antelo, Catharine Aquino, Álvaro Aranguren‐Ibáñez, Luiza Araujo, Hitler Francois Vasquez Arevalo, J. M. G. Arevalo, Carme Arnan, Lucia Elena Alvarado-Arnez, Fernanda Arredondo, Matthew Arthur, Freddy Asenjo, Thomas Saw Aung, Juliette Auvinet, Nuria Aventin, Sadaf Ayaz, Silva Baburyan, Abd-Manaaf Bakere, Katrin Bakhl, Thais Fernanda Bartelli, Erdenetsetseg Batdelger, François Baudon, Kevin Becher, Carla Bello, Médine Benchouaia, Hannah Benisty, Anne‐Sophie Benoiston, Joseph Benson, Diego Benítez, Juliana Bernardes, Denis Bertrand, Silvia Beurmann, Tristan Bitard‐Feildel, Lucie Bittner, Christina Black, Guillaume Blanc, Brittany Blyther, Toni Bode, Julia Boeri, Bazartseren Boldgiv, Kevin Bolzli, Alexia Bordigoni, Ciro Borrelli, Sonia Bouchard, Jean‐Pierre Bouly, Alicia Boyd, Gabriela P. Branco, Alessandra Breschi, Björn Brindefalk, Christian Brion, Alan C. Briones, Paulina Buczansla, Catherine Burke, A. Millie Burrell, Alina Butova, Irvind Buttar, Jalia Bynoe, Sven Bönigk, Kari O. Bøifot, Hiram Caballero, X. Cai, Dayana Calderón, Angela Cantillo, M. Carbajo Carbajo, Alessandra Carbone, Anais Cardenas, Katerine Carrillo-Castro, Laurie Casalot, S Obredor Castro, Ana V. Castro, Astred Castro, Ana Valeria Castro, Simone Cawthorne, Jonathan Cedillo, Salama Chaker, Jasna Chalangal, Allison Chan, Anastasia I. Chasapi, Starr Chatziefthimiou, Sreya Ray Chaudhuri, Akash Keluth Chavan, Francisco Chavez, Gregory Chem, Xiaohong Chen, Michelle Chen, Jenn-Wei Chen, Ariel Chernomoretz, Allaeddine Chettouh, Daisy Cheung, Diana Chicas, Shirley Chiu, Hira Choudhry, Carl Chrispin, Kianna Ciaramella, Erika Alejandra Cifuentes, Jake Cohen, David A. Coil, Sylvie Collin, Colleen Conger, Romain Conte, Flavia Corsi, Cecilia N. Cossio, Ana Flávia D.V. Costa, Delisia Cuebas, Bruno D’Alessandro, Katherine Dahlhausen, Aaron E. Darling, Pujita Das, Lucinda B. Davenport, Laurent David, Natalie R. Davidson, Gargi Dayama, Stéphane Delmas, Chris Deng, Chloé Dequeker, Alexandre Désert, Monika Devi, Felipe Segato Dezem, Clara N. Dias, Timothy Ryan Donahoe, S. Dorado, LaShonda Dorsey, V. A. Dotsenko, Steven Du, Alexandra Dutan, Naya A. Eady, Jonathan A. Eisen, Miar Elaskandrany, Lennard Epping, Juan Pablo Escalera-Antezana, Cassandra L. Ettinger, Iqra Faiz, Luice Fan, Nadine Farhat, Emile Faure, Fazlina Fauzi, Charlie Feigin, Skye Felice, Laís Pereira Ferreira, Gabriel Figueroa, Aubin Fleiss, Denisse Flores, Jhovana L. Velasco Flores, Marcos A. Fonseca, Jonathan Foox, Juan Carlos Forero, A Cucinotta Francis, Kelly French, Pablo Fresia, Jacob E. Friedman, Jaime J. Fuentes, Josephine Galipon, Mathilde Garcia, Laura Garcia, Catalina García, Annie Geiger, Samuel M. Gerner, Sonia L. Ghose, Đào Phương Giang, Matías Giménez, Donato Giovannelli, Dedan Githae, Spyridon Gkotzis, Liliana Godoy, Samantha L. Goldman, Gaston H. Gonnet, Juana Gonzalez, Andrea María Moreno González, Camila Gonzalez-Poblete, Andrew Gray, Tranette Gregory, Charlotte Greselle, Sophie Guasco, Juan José Martínez Guerra, Nika Gurianova, Wolfgang Haehr, Sebastien Halary, Felix Hartkopf, Jaden J. A. Hastings,
We present a global atlas of 4,728 metagenomic samples from mass-transit systems in 60 cities over 3 years, representing the first systematic, worldwide catalog of the urban microbial ecosystem. This atlas provides an annotated, geospatial profile of microbial strains, functional characteristics, antimicrobial resistance (AMR) markers, and genetic elements, including 10,928 viruses, 1,302 bacteria, 2 archaea, and 838,532 CRISPR arrays not found in reference databases. We identified 4,246 known species ...
Cell Press
ForestPlots.net, Cecilia Blundo, Julieta Carilla, Ricardo Grau, Agustina Malizia, Lucio R. Malizia, Oriana Osinaga-Acosta, Michael Bird, Matt Bradford, Damien Catchpole, Andrew Ford, Andrew W. Graham, David Hilbert, J. Kemp, Susan Laurance, William F. Laurance, Francoise Yoko Ishida, Andrew Marshall, Catherine E. Waite, Hannsjoerg Woell, Jean‐François Bastin, Marijn Bauters, Hans Beeckman, Pfascal Boeckx, Jan Bogaert, Charles De Cannière, Thalès de Haulleville, Jean‐Louis Doucet, Olivier J. Hardy, Wannes Hubau, Elizabeth Kearsley, Hans Verbeeck, Jason Vleminckx, Steven W. Brewer, Alfredo Alarcón, Alejandro Araujo‐Murakami, E.J.M.M. Arets, Luzmila Arroyo, Ezequiel Chavez, Todd Fredericksen, René Guillén Villaroel, Gloria Gutierrez Sibauty, Timothy J. Killeen, Juan Carlos Licona, John Lleigue, Casimiro Mendoza, Samaria Murakami, Alexander Parada Gutierrez, Guido Pardo, Marielos Peña‐Claros, Lourens Poorter, Marisol Toledo, Jeanneth Villalobos Cayo, Laura Jessica Viscarra, Vincent Antoine Vos, Jorge Ahumada, Everton Almeida, Jarcilene Silva de Almeida‐Cortez, Edmar Almeida de Oliveira, Wesley Alves da Cruz, Atila Alves de Oliveira, Fabrício Alvim Carvalho, Irina Amorim, Ana Andrade, Fernanda Antunes Carvalho, Simone Aparecida Vieira, Ana Carla Medeiros Morato de Aquino, Luiz E. O. C. Aragão, Ana Cláudia Araújo, Marco Antônio Assis, José Ataliba Mantelli Aboin Gomes, Fabrício Baccaro, Plínio Barbosa de Camargo, Paulo Eduardo Barni, Jorcely Barroso, Luis Carlos Bernacci, Kauane Maiara Bordin, Marcelo Brilhante de Medeiros, Igor S. Broggio, José Luís Camargo, Domingos Cardoso, Maria Antônia Carniello, André Luis Casarin Rochelle, Carolina V. Castilho, Antônio Alberto Jorge Farias Castro, Wendeson Castro, Sabina Cerruto Ribeiro, Flávia R. C. Costa, Rodrigo Costa de Oliveira, Italo Coutinho, John Cunha, Lola da Costa, L Ferreira, Richarlly da Costa Silva, Marta da Graça Zacarias Simbine, Vitor de Andrade Kamimura, Haroldo Cavalcante de Lima, Lia de Oliveira Melo, Luciano de Queiroz, José Romualdo de Sousa Lima, Mário M. Espírito‐Santo, Tomas Domingues, Nayane Cristina Candida dos Santos Prestes, Steffan Eduardo Silva Carneiro, Fernando Elias, Gabriel Eliseu, Thaíse Emilio, Camila Laís Farrapo, Letícia Fernandes, Gustavo Ferreira, Joice Ferreira, Leandro Valle Ferreira, Socorro Ferreira, Marcelo Fragomeni Simon, Maria Aparecida Freitas, Queila S. García, Ângelo Gilberto Manzatto, Paulo Maurı́cio Lima de Alencastro Graça, Frederico Augusto Guimarães Guilherme, Eduardo Hase, Niro Higuchi, Mariana Iguatemy, Reinaldo Imbrózio Barbosa, Margarita Jaramillo, Carlos Joly, Joice Klipel, Iêda Leão do Amaral, Carolina Levis, Antonio S. Lima, Maurício Lima Dan, Aline Pontes Lopes, Herison Madeiros, William E. Magnusson, Rubens Manoel dos Santos, Beatriz Schwantes Marimon, Ben Hur Marimon, Roberta Marotti Martelletti Grillo, Luiz Antônio Martinelli, Simone Matias Reis, Salomão de Sousa Medeiros, Milton Serpa de Meira, Thiago Metzker, Paulo S. Morandi, Natanael Moreira do Nascimento, Magna Moura, Sandra Cristina Müller, László Nagy, Henrique Eduardo Mendonça Nascimento, Marcelo Trindade Nascimento, Adriano Nogueira Lima, Raimunda Oliveira de Araújo, Jhonathan Oliveira Silva, M Pansonato, Gabriel Pavan Sabino, Karla Maria Pedra de Abreu, Pablo José Francisco Pena Rodrigues, María Teresa Fernández Piedade, Domingos de Jesus Rodrigues, José Roberto Rodrigues Pinto, Carlos Alberto Quesada, Eliana Ramos, Rafael Ramos, Priscyla Rodrigues, Thaiane R. Sousa, Rafael Salomão, Flávia Delgado Santana, M. A. Scaranello, Rodrigo Scarton Bergamin, Juliana Schietti, Jochen Schöngart, Gustavo Schwartz, Natalino Silva, Marcos Silveira, Cristiana Simão Seixas, Marta da Graça Zacarias Simbine, Ana Cláudia Mércio Loredo Souza, Priscila Souza, Rodolfo Souza, Tereza Cristina Souza Spósito, Edson JF Stefani, Julio Daniel do Vale, Ima Célia Guimarães Vieira, Dora Maria Villela, Marcos Salgado Vital, Harón Abrahim Magalháes Xaud, Kátia Janaína Zanini, Charles Eugene Zartman, Nur Khalish Hafizhah Ideris, Faizah binti Hj Metali, Kamariah Abu Salim, Muhd Shahruney Saparudin, Rafizah Mat Serudin, Rahayu Sukmaria Sukri, Serge K. Begne, George B. Chuyong, Marie Noël Kamdem Djuikouo, Christelle Gonmadje, Murielle Simo‐Droissart, Bonaventure Sonké, Hermann Taedoumg, Lise Zemagho, Sean C. Thomas, Fidèle Baya, Gustavo Saiz, Javier E. Silva‐Espejo, Dexiang Chen, Alan Hamilton, Yide Li, Tushou Luo, Shukui Niu, Han Xu, Zhang Zhou, Esteban Álvarez‐Dávila, Juan Carlos Andrés Escobar, Henry Arellano-Peña, Jaime Cabezas Duarte, Jhon Calderón, Lina Maria Corrales Bravo, Borish Cuadrado, Hermes Cuadros, Alvaro Duque, Luisa Fernanda Duque, Sandra Milena Espinosa, Rebeca Franke‐Ante, Hernando García, Alejandro Gómez, Roy González‐M., Álvaro Idárraga-Piedrahíta, E. Jiménez, Rubén Jurado, Wilmar López Oviedo, René López Camacho, Omar Aurelio Melo Cruz, Irina Mendoza Polo, Edwin Paky, Karen Pérez, Angel Pijachi, Camila Pizano, Adriana Prieto, Laura Ramos, Zorayda Restrepo Correa, James Richardson, Elkin Rodríguez, Gina M. Rodriguez M., Agustín Rudas, Pablo Stevenson, Markéta Chudomelová, Martin Dančák, Radim Hédl, Stanislav Lhota, Martin Svátek, Jacques Mukinzi, Corneille E. N. Ewango, Térese B. Hart, Emmanuel Kasongo Yakusu, Janvier Lisingo, Jean‐Remy Makana, Faustin M. Mbayu, Benjamin Toirambe, John Tshibamba Mukendi, Lars Peter Kvist, Gustav Nebel, Selene Báez, Carlos Céron, Daniel M. Griffith, Juan Ernesto Guevara Andino, David Neill, Walter Palacios, Maria Cristina Peñuela-Mora, Gonzalo Rivas‐Torres, Gorky Villa, Sheleme Demissie, Tadesse Woldemariam Gole, Techane Gonfa, Kalle Ruokolainen, Michel Baisie, Fabrice Bénédet, Wemo Betian, Vincent Bézard, Damien Bonal, Jérôme Chave, Vincent Droissart, Sylvie Gourlet‐Fleury, Annette Hladik, Nicolas Labrière, Pétrus Naisso, Maxime Réjou‐Méchain, Plinio Sist, Lilian Blanc, Benoît Burban, Géraldine Derroire, Aurélie Dourdain, Clément Stahl, Natacha Nssi Bengone, Éric Chézeaux, Fidèle Evouna Ondo,
Tropical forests are the most diverse and productive ecosystems on Earth. While better understanding of these forests is critical for our collective future, until quite recently efforts to measure and monitor them have been largely disconnected. Networking is essential to discover the answers to questions that transcend borders and the horizons of funding agencies. Here we show how a global community is responding to the challenges of tropical ecosystem research with diverse teams measuring forests ...
Elsevier BV

Pedro Nicolau‐Neto, Paulo Thiago de Souza-Santos, Mariana Severo Ramundo, Priscila Valverde, Ivanir Martins, Izabella Costa Santos, Fernando Luiz Dias, Tatiana de Almeida Simão, Luís Felipe Ribeiro Pinto,
Laryngeal squamous cell carcinoma (LSCC) is one of the most incident tumors in the world, especially in developing countries, such as Brazil. Different from other tumors, LSCC prognosis did not improve during the past four decades. Therefore, the objective of this study was to develop biomarkers that can predict LSCC patient's prognosis.Transcriptome analysis pointed out 287 overexpressed genes in LSCC in comparison to adjacent mucosa. Among these, a gene-pattern signature was created with 24 genes ...
Tópico(s): Cancer-related molecular mechanisms research
2020 - Multidisciplinary Digital Publishing Institute | Cancers

Cleandra Gregório, Sheila Coelho Soares-Lima, Bárbara Alemar, Mariana Recamonde‐Mendoza, Diego Camuzi, Paulo Thiago de Souza-Santos, Raquel Camara Rivero, Simone Márcia dos Santos Machado, Alessandro Bersch Osvaldt, Patrícia Ashton‐Prolla, Luís Felipe Ribeiro Pinto,
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with high mortality rates. PDAC initiation and progression are promoted by genetic and epigenetic dysregulation. Here, we aimed to characterize the PDAC DNA methylome in search of novel altered pathways associated with tumor development. We examined the genome-wide DNA methylation profile of PDAC in an exploratory cohort including the comparative analyses of tumoral and non-tumoral pancreatic tissues (PT). Pathway enrichment analysis ...
Tópico(s): Genetic Syndromes and Imprinting
2020 - Multidisciplinary Digital Publishing Institute | Cancers

A. P�rez, J�ssica Andrade‐Da‐Costa, Waldemir De Souza, Michelle de Souza Ferreira, Mariana Boroni, Ivanir De Oliveira, Carlos Alberto Freire‐Neto, Bruno F. Fernandes, Crist�v�o De Lanna, Paulo Thiago de Souza-Santos, Jos� Morgado‐D�az, Julio Cesar Madureira de‐Freitas‐Junior,
Changes in protein levels in different components of the apical junctional complex occur in colorectal cancer (CRC). Claudin‑3 is one of the main constituents of tight junctions, and its overexpression can increase the paracellular flux of macromolecules, as well as the malignant potential of CRC cells. The aim of this study was to investigate the molecular mechanisms involved in the regulation of claudin‑3 and its prognostic value in CRC. In silico evaluation in each of the CRC consensus molecular ...
Tópico(s): Colorectal Cancer Screening and Detection
2020 - Elsevier BV | Oncology Reports

Thiago Moraes, Paulo Amorim, Jorge Vicente Lopes da Silva, Hélio Pedrini,
Several medical imaging techniques have been employed to create visual representations of internal anatomic structures, such as organs and tissues, for clinical procedures. Diagnosis and treatment of diseases have benefited from the use of imaging modalities, such as computed tomography, magnetic resonance imaging, ultrasonography, mammography, and photon emission tomography. Interpolation is a method for generating new data points on a regular grid from a set of known data points, as result of ...
Tópico(s): Advanced Vision and Imaging
2019 - Taylor & Francis | Computer Methods in Biomechanics and Biomedical Engineering Imaging & Visualization

Thiago Bomfim, Paulo Varandas,
We introduce a gluing orbit property, weaker than specification, for both continuous maps and flows. We prove that flows with the C1-robust gluing orbit property are uniformly hyperbolic and that every uniformly hyperbolic flow satisfies the gluing orbit property. We also prove a level-1 large deviations principle and a level-2 large deviations lower bound for semiflows with the gluing orbit property. As a consequence we establish a level-1 large deviations principle for hyperbolic flows and every ...
Tópico(s): Advanced Differential Equations and Dynamical Systems
2019 - Elsevier BV | Journal of Differential Equations

Jennifer Watling, Myrtle P. Shock, Guilherme Mongeló, Fernando Ozório de Almeida, Thiago Kater, Paulo Eduardo de Oliveira, Eduardo Góes Neves,
Southwestern Amazonia is considered an early centre of plant domestication in the New World, but most of the evidence for this hypothesis comes from genetic data since systematic archaeological fieldwork in the area is recent. This paper provides first-hand archaeobotanical evidence of food production from early and middle Holocene (ca. 9,000-5000 cal. BP) deposits at Teotonio, an open-air site located on a 40 m-high bluff on the south bank of the Madeira river. Such evidence includes the presence ...
Tópico(s): Indigenous Health and Education
2018 - Public Library of Science | PLoS ONE

Pedro Nicolau‐Neto, Nathalia Meireles Da Costa, Paulo Thiago de Souza Santos, Isabela M. Gonzaga, Maria Aparecida dos Santos Ferreira, Simone Guaraldi, Miguel Ângelo Martins Moreira, Héctor N. Seuánez, Lilian Brewer, Anke Bergmann, Mariana Boroni, André Luiz Mencalha, Cléber Dario Pinto Kruel, Sheila Coelho Soares-Lima, Dominic Esposito, T.A. Simão, Luís Felipe Ribeiro Pinto,
Esophageal squamous cell carcinoma (ESCC) presents poor prognosis, and patients diagnosed with this tumor currently lack target treatments. Therefore, in order to identify potential targets for ESCC treatment, we carried out a transcriptome analysis with ESCC and paired nonmalignant surrounding mucosa samples, followed by a master regulator analysis, and further explored the role of the identified central regulatory genes through in vivo and in vitro assays. Among the transcription factors deregulated/ ...
Tópico(s): Pancreatic and Hepatic Oncology Research
2018 - Impact Journals LLC | Oncotarget

Josiane F. Silva, Izabella C. Correa, Thiago Diniz, Paulo Marcelo de Andrade Lima, Roger Lyrio dos Santos, Steyner F. Côrtes, Cândido Celso Coimbra, Virgı́nia S. Lemos,
The understanding of obsesity-related vascular dysfunction remains controversial mainly because of the diseases associated with vascular injury. Exercise training is known to prevent vascular dysfunction. Using an obesity model without comorbidities, we aimed at investigating the underlying mechanism of vascular dysfunction and how exercise interferes with this process.High-sugar diet was used to induce obesity in mice. Exercise training was performed 5 days/week. Body weight, energy intake, and ...
Tópico(s): Adipose Tissue and Metabolism
2016 - Frontiers Media | Frontiers in Physiology

Ester A. Barreto, Paulo Thiago de Souza-Santos, Anke Bergmann, Ivanir Martins de Oliveira, Luciana Wernersbach Pinto, Tânia Cristina Moita Blanco, Ana Rossini, Cleber Dario Pinto Kruel, Rodolpho Mattos Albano, Luís Felipe Ribeiro Pinto,
Tópico(s): RNA modifications and cancer
2016 - Elsevier BV | Experimental and Molecular Pathology