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Artigo Revisado por pares

Carl V. Granger, Marsha Carlin, Pedro Miguel Mendoza Díaz, Jane Dorval, Steve Forer, Corby Kessler, John L. Melvin, Lawrence S. Miller, Richard V. Riggs, Pamela Roberts,

Medical necessity is a legal, not medical, term. Depending on the stakeholder's point of view, it may seem less about human need and dispensing medical care and more about a web of rules, rulings, regulations, and manuals, especially for Medicare patients, who use the lion's share of rehabilitation services. In other words, the term medical necessity seems, to some stakeholders, to refer more to what determines payment by Medicare instead of what should be done to determine optimal patient health. ...

Tópico(s): Medical Malpractice and Liability Issues

2009 - Lippincott Williams & Wilkins | American Journal of Physical Medicine & Rehabilitation

Artigo Revisado por pares

Bethany Lusch, Pedro D. Maia, J. Nathan Kutz,

Determining the interactions and causal relationships between nodes in an unknown networked dynamical system from measurement data alone is a challenging, contemporary task across the physical, biological, and engineering sciences. Statistical methods, such as the increasingly popular Granger causality, are being broadly applied for data-driven discovery of connectivity in fields from economics to neuroscience. A common version of the algorithm is called pairwise-conditional Granger causality, which ...

Tópico(s): Neural dynamics and brain function

2016 - American Physical Society | Physical review. E

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Cesar Couto, Marco Túlio Valente, Pedro Pires, André Hora, Nicolas Anquetil, Roberto S. Bigonha,

Despite the increasing number of bug analysis tools for exploring bugs in software systems, there are no tools supporting the investigation of causality relationships between internal quality metrics and bugs. In this paper, we propose an extension of the BugMaps tool called BugMaps-Granger that allows the analysis of source code properties that are more likely to cause bugs. For this purpose, we relied on the Granger Causality Test to evaluate whether past changes to a given time series of source ...

Tópico(s): Software System Performance and Reliability

2014 - Springer Science+Business Media | Journal of Software Engineering Research and Development

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Fernanda S. Matias, Leonardo L. Gollo, Pedro V. Carelli, Steven L. Bressler, Mauro Copelli, Claudio R. Mirasso,

Different measures of directional influence have been employed to infer effective connectivity in the brain. When the connectivity between two regions is such that one of them (the sender) strongly influences the other (the receiver), a positive phase lag is often expected. The assumption is that the time difference implicit in the relative phase reflects the transmission time of neuronal activity. However, Brovelli et al. (2004) observed that, in monkeys engaged in processing a cognitive task, a dominant ...

Tópico(s): Nonlinear Dynamics and Pattern Formation

2014 - Elsevier BV | NeuroImage

Revisão Acesso aberto Brasil Produção Nacional Revisado por pares

João Sérgio Neves, Marta Borges‐Canha, Francisco Vasques‐Nóvoa, Jennifer B. Green, Lawrence A. Leiter, Christopher B. Granger, Davide Carvalho, Adelino Leite‐Moreira, Adrian F. Hernandez, Stefano Del Prato, John J.V. McMurray, João Pedro Ferreira,

Sodium-glucose cotransporter-2 (SGLT2) inhibitors and GLP-1 receptor agonists (GLP-1 RAs) reduce adverse cardiovascular outcomes in type 2 diabetes (T2D). However, the efficacy of combination therapy is unclear. The aim of this study was to evaluate the effects of GLP-1 RAs on cardiovascular outcomes in patients with T2D treated with or without SGLT2 inhibitors. Post hoc analysis of Harmony Outcomes (Albiglutide and Cardiovascular Outcomes in Patients With Type 2 Diabetes and Cardiovascular Disease) ...

Tópico(s): Diabetes Management and Research

2023 - Elsevier BV | Journal of the American College of Cardiology

Carta Acesso aberto Revisado por pares

Karl Friston,

... based. These reservations are technical and formal: Technically, Granger causal analysis (GCA) rests on the theory of Martingales, which requires random fluctuations in the brain to be infinitely ‘rough’ (like white noise). Pedro Valdes Sosa and I (Valdes-Sosa and Friston, ...

Tópico(s): Advanced Neuroimaging Techniques and Applications

2009 - Elsevier BV | NeuroImage

Artigo Brasil Produção Nacional Revisado por pares

João Ricardo Sato, Edson Amaro, Daniel Y. Takahashi, Marcelo de Maria Felix, Michael Brammer, Pedro A. Morettin,

Functional magnetic resonance imaging (fMRI) is widely used to identify neural correlates of cognitive tasks. However, the analysis of functional connectivity is crucial to understanding neural dynamics. Although many studies of cerebral circuitry have revealed adaptative behavior, which can change during the course of the experiment, most of contemporary connectivity studies are based on correlational analysis or structural equations analysis, assuming a time-invariant connectivity structure. In ...

Tópico(s): Advanced Neuroimaging Techniques and Applications

2006 - Elsevier BV | NeuroImage

Artigo Acesso aberto Revisado por pares

Renato D. Lópes, Patrícia O. Guimarães, Brad J. Kolls, Daniel Wojdyla, Cheryl Bushnell, Michael G. Hanna, J. Donald Easton, Laine Thomas, Lars Wallentin, Sana M. Al‐Khatib, Claes Held, Pedro Gabriel Melo de Barros e Silva, John H. Alexander, Christopher B. Granger, Hans‐Christoph Diener,

We investigated the frequency and characteristics of intracranial hemorrhage (ICH), the factors associated with the risk of ICH, and outcomes post-ICH overall and by randomized treatment. We identified patients with ICH from the overall trial population enrolled in the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation trial who received ≥1 dose of the study drug (n = 18 140). ICH was adjudicated by a central committee. Cox regression models were used to identify ...

Tópico(s): Acute Ischemic Stroke Management

2017 - Elsevier BV | Blood

Artigo Acesso aberto Revisado por pares

Dragoş Vinereanu, Renato D. Lópes, Hillary Mulder, Bernard J. Gersh, Michael G. Hanna, Pedro Gabriel Melo de Barros e Silva, Dan Atar, Lars Wallentin, Christopher B. Granger, John H. Alexander,

Few data exist on the long-term outcomes of patients with spontaneous echo contrast (SEC), left atrial/left atrial appendage (LA/LAA) thrombus, and complex aortic plaque (CAP), in patients with atrial fibrillation receiving oral anticoagulation. We explored the relationship between these 3 echocardiographic findings and clinical outcomes, and the comparative efficacy and safety of apixaban and warfarin for each finding.Patients from the ARISTOTLE trial (Apixaban for Reduction in Stroke and Other Thromboembolic ...

Tópico(s): Cardiac Imaging and Diagnostics

2017 - Lippincott Williams & Wilkins | Stroke

Artigo Brasil Produção Nacional Revisado por pares

Dragoş Vinereanu, Renato D. Lópes, M. Cecilia Bahit, Denis Xavier, Jie Jiang, Hussein R. Al‐Khalidi, Wensheng He, Ying Xian, A. Ciobanu, Deepak Kamath, Keith A.A. Fox, Meena P. Rao, Sean D. Pokorney, Otávio Berwanger, Carlos Tajer, Pedro Gabriel Melo de Barros e Silva, Mayme L. Roettig, Yong Huo, Christopher B. Granger, Justo Carbajales, Javier Neri Ceferino Gómez, Mario Principato, María Alejandra Von Wulffen, Jorge Galperín Rafael Salvador Acunzo, Ricardo Renato Bonato, Natalia Ciampi, Alberto Babil Marani, Cristian Gustavo Panigadi, Silvia Gabriela Pastura, Leonardo Martín Onetto, Cecilia Rafaela Moya, Nadia Budassi, M. Díaz del Valle, Daniel Camerini, Enrique Monjes, Federico Zabala, Juan Pablo Antonio Ricart, Luis Medesani, Eduardo Noe Ortuño Campos, Fabián Ferroni, Mariana Foa Torres, Daniel Omar Fassi, Fernando Javier Díaz Bosio, Gabriel E. Pérez Baztarrica, Teresa Zúñiga Infantas, Daniela Perlo, Celso Fernando García, Rubén García Durán, Luisina García Durán, Cecilia Alejandra Pettinari, Marisa L. Vico, Paulina Virginia Lanchiotti, Mariela Soledad Gómez, Carlos Poy, Franco Sebastián Grazziani, Marcela Julieta Laspina, María Laura Poy, M. Cecilia Bahit, Carlos Tajer, Marilia ia Ríos García, Renato D. Lópes, Pedro Gabriel Melo de Barros e Silva, Otávio Berwanger, Flávia Egydio, Elissa Restelli, Anelise Kawakami, Tamara Colaiácovo Soares, Mayara Vioto Valois, Tauane Bello Duarte, Lilian Mazza Barbosa, Ângelo Amato Vicenzo de Paola, Thiago Librelon Pimenta, Gabriela Dal Moro Jeronimo, Bruna S. Fernandes da Costa, Enia Lúcia Coutinho, Andressa Zulmira Avila Guerrero, Lília Nigro Maia, Marcelo Arruda Nakazone, Maria Angelica Teixeira Lemos, Osana Costa, Ana Paula Demore, Roberta Brito, Camila Dal Bon Melo, Nadielly Codonho Góes, Osvaldo Lorenço, Luiz Otavio Maia Gonçalves, Kátia Nishiama, Tiago Aparecido Maschio de Lima, Luciano Marcelo Backes, Keyla Liliana Alves de Lima Deucher, Milena P. Rodrigues, Dúnnia M.B. Baldissera, José Basileu Caos Reolão, Tais Alves dos Santos, Fernanda Michel Birck Freisleben, Níncia Lucca da Silveira Kaross, Jéssika Tzervieczenski Montovani, Maiara Cantarelli, Aline Lucion, Luciano do Amarante, Priscila Foscarini, Claudia de Mello Perez, Fernanda Ribeiro França, Lisa Fialho, Helena Cramer Veiga Rey, Epotamênides Maria Good God, Estêvão Lanna Figueiredo, Gustavo Fonseca Werner, Jose Carlos de Faria Garcia, Bruna Azevedo, Luiz Carlos Vianna Barbosa, Ernaldo Pardi, Márcia Domingos Oliveira, Toshie Martinelli, Roseli Gomes Cavalini, Michele Santos Montoni de Moraes, Adalberto Menezes Lorga Filho, Eduardo Palmegiani, Thiago Baccilli Cury Megid, C. Queirantes, Thamyres Santini Arroyo Cruz, Pengkang He, Xiaolan Zhou, N. Zhou, Mingzhong Zhao, Juan Yu, Yong Cheng, Lijun Wang, Lili Liu, Shuwang Liu, Lei Li, Aihua Li, Xiaochen Yuan, Guangwei Xia, Zhirong Wang, Chengzong Li, Wensu Chen, Qiang Tang, Qunzhong Tang, Weiting Xu, Xinyi Zhu, Bin Hou, Wenjian Ma, Wang Chong‐quan, Qiaoyun Jin, Jianan Wang, Xiaojie Xie, Johny Joseph, Deepak Davidson, Joby Thomas, Tony V. Kunjumon, Tibin Stephen, Kamlesh Fatania, Gaurav Rathi, Kinjal Garala, Dhruval Doshi, Kiron Varghese, Srilakshmi MA, Lumin Sheeba, Shantha Kumar, Malipeddi Bhaskara Rao, Kodem Damodara Rao, Anjan Kumar Vuriya, Mandula Padma Kumari, Bidita Khandelwal, Mona Dhakal, Nitin Srivastava, Dheeraj Khatri, Shova Moktan, Rajeev Gupta, Sanjeeb Roy, Kapil Kumawat, Mukesh Sharma, Konika Sharma, Narendra Jathappa, B.H. Lokesh, Shilpa Kariyappa, Agrawal Leela, K.C. Someshwara, Soaham Desai, Devangi Desai, Kunj Patel, Sujal Patel, Maulik Bhartiya, Bhupendra Narayan Mahanta, Dibya Jyoti Dutta, Ghanashyam Rajkonwer, Sandeep Kumar Gupta, Ashok Kumar Mishra, Akansha Singh, Naveen Kesarwani, Shivendra Kumar, Ovidiu Chioncel, Adriana Bălan, Nicolae Cârstea, G. Tatu Chitoiu, Stelian Cornaciu, Mircea Cinteză, Roxana Cristina Rimbaş, Doina Dimulescu, Luminita Ionescu, Ana Gabriela Fruntelata, Nicoleta Dumitru, Dan Gaita, Roxana Pleavă, Adriana Ilieșiu, Gabriela Uscoiu, Daniel Lighezan, Roxana Buzaș, Crina Sinescu, Anamaria Avram, S. Mihaila, Ruxandra Drăgoi Galrinho, Ștefania Lucia Magda, Lavinia Matei,

Oral anticoagulation is underused in patients with atrial fibrillation. We assessed the impact of a multifaceted educational intervention, versus usual care, on oral anticoagulant use in patients with atrial fibrillation.This study was a two-arm, prospective, international, cluster-randomised, controlled trial. Patients were included who had atrial fibrillation and an indication for oral anticoagulation. Clusters were randomised (1:1) to receive a quality improvement educational intervention (intervention ...

Tópico(s): Acute Ischemic Stroke Management

2017 - Elsevier BV | The Lancet

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Renato D. Lópes, Pedro Gabriel Melo de Barros e Silva, Isabella de Andrade Jesuíno, Eliana Vieira Santucci, Lilian Mazza Barbosa, Lucas Petri Damiani, Renato Hideo Nakagawa Santos, Lígia Nasi Laranjeira, Frederico Toledo Campo Dall Orto, Pedro Beraldo de Andrade, Igor Ribeiro de Castro Bienert, John H. Alexander, Christopher B. Granger, Otávio Berwanger,

Loading doses of atorvastatin did not show reduction on clinical outcomes in the overall population of patients with acute coronary syndrome (ACS) enrolled in the Statins Evaluation in Coronary Procedures and Revascularization (SECURE-PCI) trial, but a potential benefit was identified in patients who subsequently underwent percutaneous coronary intervention (PCI).To determine whether periprocedural loading doses of atorvastatin are associated with decreased 30-day major adverse cardiovascular events ( ...

Tópico(s): Coronary Interventions and Diagnostics

2018 - American Medical Association | JAMA Cardiology

Artigo Revisado por pares

Stephan A. Mayer, Pedro Kurtz, Allison Wyman, Gene Sung, Alan S. Multz, Joseph Varón, Christopher B. Granger, Kurt Kleinschmidt, Marc Lapointe, W. Frank Peacock, Jason N. Katz, Joel M. Gore, Brian J. O’Neil, Frederick A. Anderson,

Objective: To determine the demographic and clinical features, hospital complications, and predictors of 90-day mortality in neurologic patients with acute severe hypertension. Design: Studying the Treatment of Acute hyperTension (STAT) was a multicenter (n = 25) observational registry of adult critical care patients with severe hypertension treated with intravenous therapy. Setting: Emergency department or intensive care unit. Patients: A qualifying blood pressure measurement >180 mm Hg systolic or > ...

Tópico(s): Neurosurgical Procedures and Complications

2011 - Lippincott Williams & Wilkins | Critical Care Medicine

Artigo Acesso aberto Revisado por pares

Pedro Luis Celso Arellano, Víctor Hugo Gualajara Estrada, Semei Coronado, José N. Martínez, Francisco Venegas-Martı́nez,

The Global Fear Index (GFI) is a measure of fear/panic based on the number of people infected and deaths due to COVID-19. This paper aims to examine the interconnection or interdependencies between the GFI and a set of global indexes related to the financial and economic activities associated with natural resources, raw materials, agribusiness, energy, metals, and mining, such as: the S&P Global Resource Index, the S&P Global Agribusiness Equity Index, the S&P Global Metals and Mining Index, and ...

Tópico(s): COVID-19 epidemiological studies

2023 - Multidisciplinary Digital Publishing Institute | Entropy

Artigo

Jun Kobayashi, M. Yoshida, S. Tarui, Masahiro Hirata, K. Takahashi, K. Naruse, S. Kasahara, Shizuyo Sano, Hye Jin Oh, M. Halbach, G. Peinkofer, S. Baumgartner, B. Krausgrill, Afsheen Fatıma, J. Hescheler, Tatjana Šarić, J. Mueller-Ehmsen, T. Kamakura, T. Makiyama, Kouta Sasaki, Tutomu HATTORI, Shoei Ohno, Yuichi Yoshida, M. Horie, T. Kimura, K. Guan, K Streckfuss-Boemeke, Friedrich Wolf, A. Azizian, M. Stauske, M. Tiburcy, Steven Wagner, Lothar Maier, W. Zimmermann, G. Hasenfuss, Ashok K. Mehta, G. L. Sequiera, Y. Sudibyo, Li Jun, Phyllis Michael Wong, R. Liew, Woo-Gab Shim, C. Dambrot, S. R. Braam, C. M. A. H. Freund, S. Van De Pas, Dorien Ward‐van Oostwaard, D. E. Atsma, C. L. Mummery, T. Shigeta, Yoshio Bandô, M. Aoyama, A. Monji, T. Mitsui, Xuejuan Cheng, T. Murohara, T. Saikawa, Shinichi Nishio, N. Takahashi, L. C. Thuc, S. Saito, A. Fukui, O. Kume, Makoto Hara, M. Nakagawa, Y. Teshima, T. Radovits, András Pál Oláh, Bence Németh, L. Hidi, E. Birtalan, G. Kokeny, Géza Szabó, B. Merkely, D. Rottlaender, Miron Wolny, L. J. Motloch, T. Gebing, Stacy Reda, U. C. Hoppe, A. Monji, Yoshio Bandô, M. Aoyama, T. Shigeta, T. Mitsui, T. Murohara, S. Feijoo-Bandin, D. Rodriguez-Penas, V. Garcia-Rua, M. F. Otero, A. Mosquera-Leal, José Ramón González–Juanatey, Miguel Lago, Klisthenis Dimitriadis, C. Tsioufis, D. Tsiachris, A. Kasiakogias, T. Psaltopoulou, V. Tzamou, A. Mazaraki, I. Andrikou, C. Pitsavos, Christodoulos Stefanadis, J. G. Mill, Sérgio Lamêgo Rodrigues, M. P. Baldo, P. Magalhaes, D. P. Capingana, Mauricio Molina, F. Herkenhoff, R. S. Cunha, Narcis Tribulová, B. Bacova, Jana Radošinská, T. Benova, V. Knezl, E. Goncalvesova, Jarosław Ślęzak, S. A. Oliveira, M. P. Okoshi, Paul Martínez, D. M. Guizoni, B. P. Torres, M. Dal Pai-Silva, K. Okoshi, A. C. Cicogna, Cinzia Padovani, A. P. Lima-Leopoldo, F. A. Allaert, P. M. Mitrovic, B. Stefanovic, Z. Vasiljevic, Alice Paladin, Milovan Radovanović, N. Radovanovic, D. Rajic, G. Matic, T. Jozic, A. Novakovic, A. Alfiadh, Naser Uddin, Duane Clark, Marion F. Freeman, G. Wilson, L. M. Burrel, O. Farouque, E. Osto, F. Fallo, M. R. Pelizzo, A. Maddalozzo, F. Corbetti, R. Montisci, R. Bellu, Thomas F. Lüscher, S. Iliceto, F. Tona, Sinan Kocaman, A. Canga, M. Cetin, M. E. Durakoglugil, T. Erdogan, Y. Cicek, M. Hanefi Bostan, A. Steinvil, O. Rogowski, S. Banai, E. Leshem-Rubinow, A. S. Halkin, Gad Keren, Allison Sarah Finkelstein, N. Mashav, S. Berliner, Yoav Arbel, N. Amabile, Charles Guérin, C. Caussin, O. Blanc-Brude, Chantal M. Boulanger, J. Li, Jiang Nan, L. Li, Ching-Pin Yang, S.- P. Nie, Z.- C. Li, Z.- C. Li, T. H. Nguyen, C. Lang Neil, A. Sverdlov, Dinh Ngo, Wilson Chan, Ye. B. Chirkov, D. Tsikas, M. Frenneaux, Joël L. Horowitz, P. Niewinski, Z. J. Engelman, M. Fudim, S. Tubek, Ewa A. Jankowska, W. Banasiak, P. Ponikowski, F. Rigo, N. Gaibazzi, E. Grolla, C. Reverberi, G. Ossena, J.- C. Reil, Jordan Tardif, I.D. Ford, Simon Lloyd, Eugene O’meara, M. Komajda, J. Borer, L. Tavazzi, K. Swedberg, M. Boehm, H. B. Erer, T. S. Guvenc, A. Kemik, S. Altay, N. Sayar, D. Oz, A. Ekmekci, A. Zencirci, S. Kul, Metin I. Eren, H. P. Holthoff, S. Zeibig, V. Boivin-Jahns, M. J. Lohse, S. Kaeaeb, S. Clauss, Richard H. Jahns, G. Muench, M. Ungerer, Patrik Henriksson, E. Westerlund, Lisbeth K. Brandt, O. Hovatta, A. Ekbom, C. Becattini, Frances M Casazza, A. Bongarzoni, C. Forgione, C. Cuccia, L. Roncon, F. Porro, L. Pignataro, G. Agnelli, D. Spirk, T. Baldi, T. Willenberg, D. Aujesky, M. Husmann, D. Hayoz, A. Brugger, B. Amann-Vesti, Ingrid Baumgärtner, N. Kucher, Diego Fernández-Henarejos Jiménez, Jorge Lobo, Anne Holley, V. Tapson, L. Moores, M. Oribe, M. Barron, R. Perez Otero, Diane Nauffal, R. D. Yusen, Tage Andersson, F. Larsen, B. Carlberg, Susan C. Soderberg, J. Pedowska-Wloszek, M. Kostrubiec, A. Labyk, Silvino Pacho, O. Dzikowska-Diduch, P. Bienias, B. Lichodziejewska, Piotr Palczewski, M. Ciurzynski, P. Pruszczyk, J. Magne, H. Mahjoub, J. C. Bologne, R. Dulgheru, L. A. Pierard, P. Pibarot, P. Lancellotti, H. Takahashi, H. Ishii, Y. Kumada, T. Aoyama, D. Kamoi, Mikako Tanaka,

Stemi: epidemiology considerations and electrocardiogram findings 143receive either an intracoronary bolus of 150 µg of DA (DA group) or normal saline (control group) at the onset of reflow obtained by primary percutaneous coronary intervention (PCI).IS was assessed both by measuring serum creatine kinase (CK) release and by performing cardiac magnetic resonance (CMR).Results: There was no difference between the two groups with regard to the duration of ischemia, the TIMI flow grade at admission and ...

Oxford University Press

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Otávio Berwanger, Renato D. Lópes, Diogo D.F. Moia, Francisco Antônio Helfenstein Fonseca, Lixin Jiang, Shaun G. Goodman, Stephen J. Nicholls, Alexander Parkhomenko, О. В. Аверков, Carlos Tajer, Germán Málaga, José Francisco Kerr Saraiva, Hélio Penna Guimarães, Pedro Gabriel Melo de Barros e Silva, Lucas Petri Damiani, Renato Hideo Nakagawa Santos, Denise Paisani, Tamiris Abait Miranda, Nanci Valeis, Leopoldo Soares Piegas, Christopher B. Granger, Harvey D. White, José Carlos Nicolau,

The efficacy of ticagrelor in the long-term post–ST-segment elevation myocardial infarction (STEMI) treated with fibrinolytic therapy remains uncertain. The purpose of this study was to evaluate the efficacy of ticagrelor when compared with clopidogrel in STEMI patients treated with fibrinolytic therapy. This international, multicenter, randomized, open-label with blinded endpoint adjudication trial enrolled 3,799 patients (age <75 years) with STEMI receiving fibrinolytic therapy. Patients were randomized ...

Tópico(s): Atrial Fibrillation Management and Outcomes

2019 - Elsevier BV | Journal of the American College of Cardiology

Artigo Revisado por pares

Otávio Berwanger, José Carlos Nicolau, Antônio Carlos Carvalho, Lixin Jiang, Shaun G. Goodman, Stephen J. Nicholls, Alexander Parkhomenko, О. В. Аверков, Carlos Tajer, Germán Málaga, José Francisco Kerr Saraiva, Francisco Antônio Helfenstein Fonseca, Hélio Penna Guimarães, Pedro Gabriel Melo de Barros e Silva, Lucas Petri Damiani, Denise Paisani, Camila M. R. Lasagno, Carolina T. Candido, Nanci Valeis, Diogo D.F. Moia, Leopoldo Soares Piegas, Christopher B. Granger, Harvey D. White, Renato D. Lópes,

The safety and efficacy of ticagrelor in patients with ST-elevation myocardial infarction (STEMI) treated with fibrinolytic therapy remain uncertain. The primary objective of the TicagRElor in pAtients with ST elevation myocardial infarction treated with Thrombolysis (TREAT) trial is to evaluate the short-term safety of ticagrelor when compared with clopidogrel in STEMI patients treated with fibrinolytic therapy. Key secondary objectives are to assess the safety and efficacy of ticagrelor compared ...

Tópico(s): Atrial Fibrillation Management and Outcomes

2018 - Elsevier BV | American Heart Journal

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Renato D. Lópes, Ariane Vieira Scarlatelli Macedo, Pedro Gabriel Melo de Barros e Silva, Renata Moll-Bernardes, André Feldman, Guilherme Arruda, Andrea Silvestre de Souza, Denílson Campos de Albuquerque, Lilian Mazza, Mayara Fraga Santos, Natalia Salvador, C. Michael Gibson, Christopher B. Granger, John H. Alexander, Olga Ferreira de Souza,

Angiotensin-converting enzyme-2 (ACE2) expression may increase due to upregulation in patients using angiotensin-converting enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARBs). Because renin-angiotensin system blockers increase levels of ACE2, a protein that facilitates coronavirus entry into cells, there is concern that these drugs could increase the risk of developing a severe and fatal form of COVID-19. The impact of discontinuing ACEI and ARBs in patients with COVID-19 remains uncertain. ...

Tópico(s): Vitamin C and Antioxidants Research

2020 - Elsevier BV | American Heart Journal

Artigo Acesso aberto Revisado por pares

Hanane Chajra, Thibaut Saguet, Corinne Granger, Lionel Breton, Pedro Pinto, Mickael Machicoane, Jean Marc Le Doussal,

Skin aging, which results from intrinsic and extrinsic factors, is characterized by a rough, uneven and wrinkled appearance of the skin at the macroscopic level. At the microscopic level, aging shows lowered keratinocyte turnover, flattened dermal-epidermal junction and reduced collagen fiber density; however, use of skin biopsies to evaluate characteristic properties of these microscopic changes is too limiting for panelists and rarely used. The development of non-invasive techniques is an opportunity ...

Tópico(s): 3D Printing in Biomedical Research

2024 - Adis, Springer Healthcare | Dermatology and Therapy

Artigo Acesso aberto Revisado por pares

Renato D. Lópes, Pedro Gabriel Melo de Barros e Silva, Lucas Petri Damiani, Renato Hideo Nakagawa Santos, John H. Alexander, Christopher B. Granger, Otávio Berwanger,

This study uses SECURE-PCI trial data to compare the effects of periprocedural loading doses of atorvastatin vs placebo on major adverse cardiac events (MACE) 12 months after randomization in patients with acute coronary syndrome (ACS) and planned invasive management.

Tópico(s): Cardiac Imaging and Diagnostics

2020 - American Medical Association | JAMA

Artigo Acesso aberto Revisado por pares

Pedro Antonio Martín Cervantes, Nuria Rueda López, Salvador Cruz Rambaud,

... life expectancy at birth.Our analysis applies the Granger causality test, more specifically its version by Dumitrescu- ... rate of hospital beds, medical staff and nurses Granger-cause the variable "life expectancy at birth", according to the Granger causality test applied to panel data (Dumitrescu-Hurlin' ... identification of those factors which exhibit a unidirectional Granger-causality relationship with life expectancy at birth. Therefore, ...

Tópico(s): Insurance, Mortality, Demography, Risk Management

2019 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health

Artigo Acesso aberto Revisado por pares

Jorge Berlanga, Pedro A Prats, Diadelis Remírez, Ricardo González, Pedro López‐Saura, Jorge Aguiar, Miriam Ojeda Ojeda, Joseph J. Boyle, Anthony J. Fitzgerald, Raymond J. Playford,

... production of oxygen-derived cytotoxic products.4Parks DA Granger DN Contributions of ischaemia and reperfusion to mucosal ... Google Scholar and free radical production,4Parks DA Granger DN Contributions of ischaemia and reperfusion to mucosal ... up-regulation of cell adhesion molecules,23Carden DL Granger DN Pathophysiology of ischaemia-reperfusion injury.J Pathol. ... 561Crossref PubMed Scopus (155) Google Scholar, 23Carden DL Granger DN Pathophysiology of ischaemia-reperfusion injury.J Pathol. ...

Tópico(s): Acute Kidney Injury Research

2002 - Elsevier BV | American Journal Of Pathology

Artigo Acesso aberto Revisado por pares

Thomas J. Sargent,

... 07350015.2013.773905Gebhard Kirchgässner, Jürgen Wolters, Uwe Hassler Granger Causality, (Sep 2012): 95–125.https://doi.org/ ... 1257/aer.97.1.530Gebhard Kirchgässner, Jürgen Wolters Granger Causality, (Jan 2007): 93–123.https://doi.org/ ... 1016/0164-0704(88)90047-XC.W.J. Granger Some recent development in a concept of causality, ... https://doi.org/10.1007/BF01973317C.W.J. Granger Causality, cointegration, and control, Journal of Economic Dynamics ... 177.https://doi.org/10.1080/00036848700000094GEBHARD KIRCHGÄSSNER Granger‐Kausalität und rationale Erwartungen, Kyklos 40, no.11 ( ...

Tópico(s): Fiscal Policies and Political Economy

1976 - University of Chicago Press | Journal of Political Economy

Artigo Revisado por pares

Jorge Garza–Rodríguez, Cecilia I. Andrade-Velasco, Karen D. Martinez-Silva, Francisco D. Renteria-Rodriguez, Pedro A. Vallejo-Castillo,

... per capita GDP positively affects population. Additionally, a Granger causality test indicated that per capita GDP is Granger-caused by population and population is Granger-caused by per capita GDP, thus revealing the ...

Tópico(s): Fiscal Policy and Economic Growth

2016 - Springer Nature | Economics bulletin

Artigo Revisado por pares

Julie A. Bokser,

... on the echo; Stroud's Lacanian reading; Gonzalez, Granger-Carrasco, and Kirk on theology; and Merrim on ... which typically during this period honored the Eucharist (Granger-Carrasco Ch. 1). 10Between 1691 and 1725, The ... been classified as literature of Mexico, not Spain (Granger-Carrasco 15). 16A similar multiplicity of identity is ...

Tópico(s): Latin American and Latino Studies

2010 - Taylor & Francis | Rhetoric Society Quarterly

Artigo

Adrian F. Hernandez, Jennifer B. Green, Salim Janmohamed, Ralph B. D’Agostino, Christopher B. Granger, Nigel C. Jones, Lawrence A. Leiter, Anne E Rosenberg, Kristina N. Sigmon, Matthew C. Somerville, Karl M. Thorpe, John J.V. McMurray, Stefano Del Prato, Stefano Del Prato, John J.V. McMurray, Ralph B. D’Agostino, Christopher B. Granger, Adrian F. Hernandez, Salim Janmohamed, Lawrence A. Leiter, Robert M. Califf, Rury R. Holman, David L. DeMets, Matthew C. Riddle, Shaun G. Goodman, Darren K. McGuire, Karen Alexander, Adam D. DeVore, Chiara Melloni, Chetan B. Patel, David C. M. Kong, Gerald S. Bloomfield, Matthew T. Roe, Pierluigi Tricoci, Robert W. Harrison, Renato D. Lópes, Robin Mathews, Rajendra Mehta, W. Schuyler Jones, Sreekanth Vemulapalli, Thomas J. Povsic, Zubin J. Eapen, Keith Dombrowski, Brad J. Kolls, J. Dedrick Jordan, Andrew P. Ambrosy, Stephen J. Greene, Aditya Mandawat, Jay Shavadia, Lauren B. Cooper, Abhinav Sharma, Patrícia O. Guimarães, Daniel J. Friedman, Matthew E. Wilson, Patricia Endsley, Tracy Gentry, Jeannie Collier, Kathleen Perez, K.E. James, Jennifer Roush, C. ARDEN III POPE, Christina Howell, Megan Johnson, M. Bailey, Joanna Cole, Teresa Akers, Beth Vandyne, Betsy Thomas, Jenny Rich, Susan Bartone, Gail Beaulieu, Kim Brown, Tuan Chau, Tamra Christian, Rebecca Coker, Deb Greene, Trevorlyn Haddock, Wendy Jenkins, Ghazala Haque, Marsha L. Marquess, Jean Pesarchick, Renee Rethaford, Allegra Stone, Firas Al- Kawas, Michelle A. Anderson, Robert Enns, Isaac Sinay, Chantal Mathieu, Victor Yordanov, Irene Hramiak, Martin Haluzı́k, Søren Galatius, Bruno Guerci, Michael A. Nauck, Ilias Migdalis, Kathryn Choon Beng Tan, Győző Kocsis, Andrea Giaccari, Moon Kyu Lee, Ernesto Muñoz, Jan H. Cornel, Kåre I. Birkeland, Miguel E. Pinto, Louie Tirador, Martyna Olesińska‐Mader, М. В. Шестакова, Larry A. Distiller, José López‐Sendón, Björn Eliasson, Chern‐En Chiang, Suphot Srimahachota, Boris Mankovsky, M. Angelyn Bethel, Kathleen Dungan, Mikhail Kosiborod, Andres Alvarisqueta, Jorge Baldovino, Diego Besada, Pedro Calella, Maria Cecilia Cantero, Patricia Castaño, Alejandro Chertkoff, Jesus Cuadrado, Luis De Loredo, Andrea Domínguez, Maria Vanesa Español, Hernan Finkelstein, Gustavo Frechtel, Jose Osvaldo Fretes, Natalia Garrido Santos, Joaquin Pablo Gonzalez, Marcos Litvak, Juan Loureyro, Laura Maffei, Natacha Maldonado, Diego Mohr Gasparini, Silvia Ines Orio, Federico Pérez Manghi, Nelson Papini, Jorgelina Sala, P. Schygiel, Georgina Sposetti, María Rosa Ulla, Fernando Verra, Silvina Zabalua, Cesar Javier Zaidman, Laurent Crenier, Corinne Debroye, Francis Duyck, André Scheen, Luc Van Gaal, Chris Vercammen, V. Damyanova, Stefan Dimitrov, Snezhina Kovacheva, L Lozanov, Viktor Margaritov, Rositsa Mihaylova-Shumkova, А. Г. Николаева, Zhasmina Stoyanova, Ronald Akhras, Yves Beaudry, Jacques Bedard, Joseph Berlingieri, R Chehayeb, Stephen Cheung, James Conway, Jean R. Cusson, Anthony Della Siega, R Dumas, Peter Dzongowski, Murdo Ferguson, Daniel Gaudet, François Grondin, Anil Kumar Gupta, Milan Gupta, Frank Halperin, Pierre-Alain Houle, Michael A. Jones, Simon Kouz, Christopher S. Kovacs, Daniel Landry, Eva Lonn, William O’Mahony, Sean Peterson, Dennis Reich, Alan J. Rosenbloom, François St-Maurice, Barna Tugwell, Saul Vizel, Vincent Woo, Tomáš Brychta, Vladimir Cech, Eva Dvořáková, Tomáš Edelsberger, Katarina Halčiaková, Jarmila Křížová, Jiří Laštůvka, Martin Piperek, Věra Prýmková, Lea Raclavska, Elena Šilhová, Robin Urbánek, Jan Vrkoč, Ulla Overgaard Andersen, Jens Brønnum-Schou, Jens D. Hove, Jan Skov Jensen, Lars Køber, Ole Peter Kristiansen, Per Lund, Thomas Melchior, Ole Nyvad, Morten Schou, Alain Boye, Didier Cadinot, D. Gouet, Patrick Henry, L. Kessler, Jean‐Daniel Lalau, Catherine Petit, Jean-Francois Thuan, Christel Voinot, Julien Vouillarmet, Christoph Axthelm, Dirk Berger, Tasso Bieler, Andreas L. Birkenfeld, Jochen Bott, Klaus Busch, Karel Caca, Julia Chevts, Torsten Donaubauer, Rudolf Erlinger, Klaus Funke, Josef Großkopf, Andreas Hagenow, Mónika Inés Hamann, Manfred Hartard, Peter Heymer, W Huppertz, Gabriele Illies, Stephan Jacob, Thomas S. Jung, Gerd Kahrmann, Petra Kast, Monika Kellerer, H Kempe, Andrei Khariouzov, Gerhard Klausmann, Christiane Klein, Uwe Kleinecke-Pohl, Klaus Kleinertz, Thorsten Koch, Christine Kosch, Babette Lorra, Joerg Luedemann, Matthias Luttermann, Stephan Maxeiner, K Milek, Andrea Moelle, Gerhard Neumann, Ruth Nischik, Edith Oehrig-Pohl, Georg Plassmann, Lars Pohlmeier, Felix Proepper, Stefan Regner, Werner Rieker, Ludger Rose, Holger Samer, Joachim Sauter, Frank Schäper, Clemens Schiffer, Juergen Schmidt, B. Scholz, J Schulze, Alexander Segner, Jochen Seufert, Helena Sigal, Joerg Steindorf, Juergen Stockhausen, Petra Stuebler, H Taeschner, Dietrich Tews, Diethelm Tschoepe, Karl Wilhelm, Helga Zeller-Stefan, Iakovos Avramidis, Stavros Bousboulas, Magdalini Bristianou, Georgios Dimitriadis, Moses Elisaf, Kalliopi Kotsa, Αndreas Μelidonis, Asimina Mitrakou,

Summary Background Glucagon-like peptide 1 receptor agonists differ in chemical structure, duration of action, and in their effects on clinical outcomes. The cardiovascular effects of once-weekly albiglutide in type 2 diabetes are unknown. We aimed to determine the safety and efficacy of albiglutide in preventing cardiovascular death, myocardial infarction, or stroke. Methods We did a double-blind, randomised, placebo-controlled trial in 610 sites across 28 countries. We randomly assigned patients aged ...

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