Adolfo Daniel Rodríguez-Carrizález, José Alberto Castellanos‐González, Esaú César Martínez‐Romero, Guillermo Miller‐Arrevillaga, David Villa‐Hernández, Pedro Pablo Hernández‐Godínez, Genaro Gabriel Ortíz, Fermín Paul Pacheco‐Moisés, Ernesto Germán Cardona‐Muñoz, Alejandra Guillermina Miranda‐Díaz,
Diabetic retinopathy (DR) is a preventable cause of visual disability. The aims of the present study were to investigate levels and behavior oxidative stress markers and mitochondrial function in non-proliferative DR (NPDR) and to establish the correlation between the severity of NPDR and markers of oxidative stress and mitochondrial function.In a transverse analysis, type 2 diabetes mellitus (T2DM) patients with mild, moderate and severe non-proliferative DR (NPDR) were evaluated for markers of oxidative ...
Tópico(s): Cardiovascular Health and Disease Prevention
2013 - Wiley | Journal of Diabetes
César Muñoz‐Fontela, Laura Marcos-Villar, Félix Hernández, Pedro Pablo Ferrer Gallego, Estefanía Rodríguez, Javier Arroyo, Shou‐Jiang Gao, Jesús Ávila, Carmen Rivas,
ABSTRACT Kaposi's sarcoma-associated herpesvirus (KSHV) is the causal agent of both KS and primary effusion lymphoma (PEL). Although treatment with paclitaxel has significant antitumor activity in KS, drug resistance represents a major obstacle for improving the overall response and survival of PEL patients. The transcriptional pattern of KSHV is cell/tissue specific, as revealed by the fact that the viral latent protein LANA2 is detected exclusively in B cells. This paper focuses on the mechanism ...
Tópico(s): Lymphoma Diagnosis and Treatment
2007 - American Society for Microbiology | Journal of Virology
Pablo Galindo‐Moreno, Pedro Hernández‐Cortés, Rosa M. Rı́os, Elena Sánchez‐Fernández, Miguel A. Camara, Francisco O’Valle,
We report the case of a 74-year-old white male patient who had worn an overdenture for the previous 6 years, retained by 4 screwed implants and a bar, who presented with an exophytic multilobed lesion of 2.5 × 2.0 cm on the anterior aspect of 1 implant neck, which was surrounded by pink-reddish tissue. All of the soft tissue around the implant was removed until the periosteum was reached. Histologic examination of the lamina propria revealed a cellular proliferation with imprecise boundaries, dense ...
Tópico(s): Bone health and treatments
2013 - Allen Press | Journal of Oral Implantology
Pablo Galindo‐Moreno, Pedro Hernández‐Cortés, José Aneiros‐Fernández, Miguel Ángel De la Cámara, Francisco Mesa, Stephen S. Wallace, Francisco O’Valle,
Abstract Objectives Our objectives were to examine vascular and cellular colonization in anorganic bovine bone ( ABB ) after 6 months of healing in human maxillary sinus augmentation grafts. Material and methods Fifty unilateral maxillary sinus augmentation procedures were performed on 50 consecutive patients. Bone cores were obtained through the implant receptor sites 6 months later and evaluated with morphological image analysis and immunohistochemical techniques. Results Image analysis revealed a ...
Tópico(s): Bone Tissue Engineering Materials
2013 - Wiley | Clinical Oral Implants Research
Pablo Galindo‐Moreno, Pedro Hernández‐Cortés, Francisco Mesa, Nelson Carranza, Gintaras Juodžbalys, Mariano Aguilar, Francisco O’Valle,
ABSTRACT Purpose: Different biomaterials have been suggested for guided bone regeneration (GBR). These might show the ideal properties to let a new bone formation in the grafted area. Among these ideal features, it is essential their controlled resorption in order to be replaced for new vital bone. Bovine bone has been used widely as a good biomaterial for GBR, however there is still an interesting controversy about its resorbable capacity. In this sense, the objective of this study was to examine ...
Tópico(s): Periodontal Regeneration and Treatments
2012 - Wiley | Clinical Implant Dentistry and Related Research
M. Sosa Henríquez, Miri Dominguez, Mary C. Navarro, Mary C. Segarra, Domingo Hernández, Pedro de Pablos‐Velasco, P. Betancor,
Because of the previous controversial findings in non-insulin-dependent diabetes mellitus (NIDDM), we measured bone-mineral density (BMD) by two different methods, studied biochemical markers of bone remodeling and calciotropic hormones (parathyroid hormone and calcitonin) in women with NIDDM, and compared the results with age-matched controls. Forty-seven women with NIDDM and 252 healthy nondiabetic women as controls were recruited for this study. BMD was measured by dual X-ray absorptiometry (DEXA) ...
Tópico(s): Parathyroid Disorders and Treatments
1996 - Elsevier BV | Journal of Diabetes and its Complications
Pablo Ruiz‐Palomino, Felipe Hernández‐Perlines, Pedro Jiménez Estévez, Santiago Gutiérrez-Broncano,
Purpose Drawing on the theories of servant leadership and upper echelons, this paper aims to highlight the mechanisms through which CEO servant leadership enhances firm innovativeness in hotels. This study aims to test a multiple mediation model by considering the mediating role of encouragement of participation (EoPART) – a high-performance human resources (HR) practice – and employees’ voice (EVOICE) in sequence. Design/methodology/approach Data were collected from HR managers of 34 hotels in the hospitality ...
Tópico(s): Innovation and Knowledge Management
2019 - Emerald Publishing Limited | International Journal of Contemporary Hospitality Management
Luis Enrique Sucar, Concha Bielza, Eduardo F. Morales, Pablo Hernández-Leal, Julio H. Zaragoza, Pedro Larrañaga,
In multi-label classification the goal is to assign an instance to a set of different classes. This task is normally addressed either by defining a compound class variable with all the possible combinations of labels (label power-set methods) or by building independent classifiers for each class (binary relevance methods). The first approach suffers from high computationally complexity, while the second approach ignores possible dependencies among classes. Chain classifiers have been recently proposed ...
Tópico(s): Spam and Phishing Detection
2013 - Elsevier BV | Pattern Recognition Letters
Pablo Fanjul‐Bolado, David Hernández‐Santos, Pedro José Lamas‐Ardisana, A.M. Pernía, Agustín Costa‐García,
This work compares the electroactivity of a conventional carbon paste electrode and non-pretreated commercially available screen-printed carbon electrodes (from Alderon Biosciences, University of Florence and DropSens) towards some benchmark redox couples like hexaammineruthenium (III), ferricyanide, p-aminophenol and hydroquinone. While cyclic voltammograms of Ru3+ did not show significative electron transfer reactivity differences between the electrodes tested, the other redox systems exhibited ...
Tópico(s): Conducting polymers and applications
2007 - Elsevier BV | Electrochimica Acta
Benito Yáñez‐Araque, Juan Pablo Sánchez-Infante Hernández, Santiago Gutiérrez-Broncano, Pedro Jiménez Estévez,
The 2030 Agenda for Sustainable Development, adopted by all United Nations member states in 2015, includes 17 Sustainable Development Goals (SDGs) to be achieved by 2030. The SDGs set the agenda for trends in corporate social responsibility (CSR), which will gain momentum in the coming years; and businesses are the key agents of countries for the development of this agenda. The importance of micro-, small- and medium-sized enterprises (MSMEs) and family businesses in the economy of a country is unquestionable; ...
Tópico(s): Corporate Social Responsibility Reporting
2020 - Elsevier BV | Journal of Business Research
Mario Pablo Estrada, Lázaro Hernández, Ángel Pérez, Pedro Rodríguez, Rafael Serrano, Roger Rubiera, A. Pedraza, Gabrìel Padrón, Walfrido Antuch, José de la Fuente, Luís Herrera,
Tópico(s): Peptidase Inhibition and Analysis
1992 - Nature Portfolio | Nature Biotechnology
Eugenio Hernandez‐Fernandez, Pedro Pablo Sánchez-Lara, Mario Ordóñez, Oscar Abelardo Ramírez‐Marroquín, Francisco G. Ávalos‐Alanís, Susana López-Cortina, Víctor M. Jiménez‐Pérez, Tannya R. Ibarra‐Rivera,
The amidation of unactivated ethyl esters with achiral and chiral 1,2-amino alcohols under microwave irradiation and base-free conditions is described. This procedure provides a convenient method for the synthesis of β-hydroxyacetamides bearing pyrazole, imidazole, and benzimidazole groups in high yields and without racemization. The protocol described herein is environmentally friendly and allows for the preparation of a wide variety of β-hydroxyacetamides, which are key intermediates in the synthesis ...
Tópico(s): Chemical Synthesis and Reactions
2014 - Elsevier BV | Tetrahedron Asymmetry
Pablo Olmedo, Antonio F. Hernández, Antonio Pla, Pedro Femia, Ana Navas‐Acién, Fernando Gil,
Fish and shellfish are an important source not only of toxic heavy metals, but also of essential elements in the diet. In this study, levels of Cu, Mn, Se and Zn have been determined in fresh, canned and frozen fish and shellfish products. A total of 485 samples of the 43 most frequently consumed fish and shellfish species in Andalusia (Southern Spain) were analyzed for essential elements content. The potential human health risks for the consumers and the nutritional value of the products analyzed ...
Tópico(s): Aquaculture Nutrition and Growth
2013 - Elsevier BV | Food and Chemical Toxicology
Ana P. Barba de la Rosa, Angélica Montoya, Pedro Pablo Martinez-Cuevas, Blanca Hernández‐Ledesma, Ma. Fabiola León‐Galván, Antonio De León‐Rodríguez, C. González,
Tópico(s): Insect Utilization and Effects
2010 - Elsevier BV | Nitric Oxide
Pedro Gutiérrez, Pablo José Borges Hernández, Emílio J. Sanz, Oscar Cardeñosa, Manuel Mas,
Although erectile dysfunction (ED) is known to hamper quality of life (QoL) of afflicted men and their partners, there are few validated instruments for assessing the couple's sexual QoL. The Sexual Life Quality of Life Questionnaire (SLQQ) was developed in the United States for this purpose, and so it has been used in clinical studies. Yet, the original description did not address some important psychometric properties included in the Food and Drug Administration 2006 guidance for patient-reported ...
Tópico(s): Sexuality, Behavior, and Technology
2009 - Elsevier BV | The Journal of Sexual Medicine
Manuel Alejandro Ramirez-Lee, Pedro Pablo Martinez-Cuevas, Héctor Rosas-Hernández, Cuauhtémoc Oros‐Ovalle, Mariela Bravo-Sánchez, Gabriel Alejandro Martínez-Castañón, Carmen González,
Silver nanoparticles (AgNPs) have been widely used because of their antimicrobial properties. However, several reports suggest that AgNPs exposure promote cardiac effects that involve nitric oxide (NO) and oxidative stress (OS). Nevertheless, there are no studies related to AgNPs-induced effects in cardiac physiology. The aim of this study was to evaluate the AgNPs direct actions on coronary vascular tone and cardiac contractility using Langendorff rat heart preparation. Low concentrations of AgNPs ( ...
Tópico(s): Hydrogen's biological and therapeutic effects
2017 - Elsevier BV | Nanomedicine Nanotechnology Biology and Medicine
Jennifer Hernández Bécares, Luis Costero, Pedro Pablo Gómez Martín,
Videogames developed in the 1970s and 1980s were modest programs created in a couple of months by a single person, who played the roles of designer, artist and programmer. Since then, videogames have evolved to become a multi-million dollar industry. Today, AAA game development involves hundreds of people working together over several years. Management and engineering requirements have changed at the same pace. Although many of the processes have been adapted over time, this is not quite true for ...
Tópico(s): Software Engineering and Design Patterns
2016 - Elsevier BV | Entertainment Computing
Cristina Blanco-Marchite, Francisco Sánchez‐Sánchez, María-Pilar López-Garrido, Mercedes Iñigez-de-Onzoño, Francisco López-Martínez, E. López-Sánchez, Lydia Álvarez, Pedro-Pablo Rodríguez-Calvo, Carmen Méndez-Hernández, Luís Fernández-Vega, J. García–Sánchez, Miguel Coca‐Prados, J. García–Sánchez, Julio Escribano,
To investigate the role of WDR36 and P53 sequence variations in POAG susceptibility.The authors performed a case-control genetic association study in 268 unrelated Spanish patients (POAG1) and 380 control subjects matched for sex, age, and ethnicity. WDR36 sequence variations were screened by either direct DNA sequencing or denaturing high-performance liquid chromatography. P53 polymorphisms p.R72P and c.97-147ins16bp were analyzed by single-nucleotide polymorphism (SNP) genotyping and PCR, respectively. ...
Tópico(s): Retinal Development and Disorders
2011 - Cadmus Press | Investigative Ophthalmology & Visual Science
Héctor Rosas-Hernández, Salma Jiménez-Badillo, Pedro Pablo Martinez-Cuevas, Eduardo Gracia‐Espino, Humberto Terrones, Mauricio Terrones, Saber M. Hussain, Syed F. Ali, Carmen González,
This study was undertaken to determine whether silver nanoparticles (Ag-45 nm NPs) induce selective and specific biological effects, such as induction of proliferation and nitric oxide (NO) production, and cytotoxicity in coronary endothelial cells (CECs), and regulation of vascular tone in isolated rat aortic rings. Physical characterization of Ag-45 nm NPs by transmission electron microscopy (TEM) demonstrated that nanoparticles ranging in size from 10 to 90 nm had biological effects on CECs. Increasing ...
Tópico(s): Advanced Nanomaterials in Catalysis
2009 - Elsevier BV | Toxicology Letters
Pablo Fanjul‐Bolado, Pedro José Lamas‐Ardisana, David Hernández‐Santos, Agustín Costa‐García,
Acetaminophenol or paracetamol is one of the most commonly used analgesics in pharmaceutical formulations. Acetaminophen is electroactive and voltammetric mechanistic studies for the electrode processes of the acetaminophenol/N-acetyl-p-quinoneimine redox system are presented. Carbon nanotubes modified screen-printed electrodes with enhanced electron transfer properties are used for the study of the electrochemical–chemical oxidation mechanism of paracetamol at pH 2.0. Quantitative analysis of paracetamol ...
Tópico(s): Analytical Chemistry and Sensors
2009 - Elsevier BV | Analytica Chimica Acta
Matías Alarcón, Pedro Soto, Francisco Hernández, Pablo Guindos,
A low-cost seismic instrumentation system (LCSIS) has been implemented and validated for the structural health monitoring of South America's first experimental 6-story light-frame timber building (Peñuelas Tower). Furthermore, coupling the LCSIS with relative humidity and temperature measuring system has allowed for investigating the ambient-induced variations of the building's dynamic properties. The LCSIS has been accomplished using six accelerographs RaspberryShake® R4SD (R4SD), which were interconnected ...
Tópico(s): Seismic Performance and Analysis
2022 - Elsevier BV | Engineering Structures
Miriam Martín, Alejandro González Orive, Pablo Lorenzo‐Luis, Alberto Hernández Creus, José Luis González–Mora, Pedro Salazar,
Abstract Novel core‐shell quinone‐rich poly(dopamine)–magnetic nanoparticles (MNPs) were prepared by using an in situ polymerization method. Catechol groups were oxidized to quinone by using a thermal treatment. MNPs were characterized by using X‐ray diffraction, X‐ray photoelectron spectroscopy, atomic force microscopy, magnetic force microscopy, UV/Vis, Fourier‐transform infrared spectroscopy, and electrochemical techniques. The hybrid nanomaterial showed an average core diameter of 17 nm and a ...
Tópico(s): Analytical Chemistry and Sensors
2014 - Wiley | ChemPhysChem
Fernando Gil, Antonio F. Hernández, Claudia Márquez, Pedro Femia, Pablo Olmedo, Olga López‐Guarnido, Antonio Pla,
Heavy metal contamination from occupational origin is a cause for concern because of its potential accumulation in the environment and in living organisms leading to long term toxic effects. This study was aimed to assess Cd, Cr, Mn, Ni and Pb levels in whole blood, urine, axillary hair and saliva from 178 individuals with occupational exposure to heavy metals. Levels of metal compounds were determined by atomic absorption spectrometry. We collected information on occupation, lifestyle habits and ...
Tópico(s): Mercury impact and mitigation studies
2011 - Elsevier BV | The Science of The Total Environment
... 456.https://doi.org/10.3390/jtaer18010023Ignacio Pérez Hernández, Pablo de Frutos Madrazo, Beatriz Rodriguez-Prado, Pedro Antonio Martin-Cervantes A gravity model to explain ...
Tópico(s): Sport and Mega-Event Impacts
1956 - University of Chicago Press | Journal of Political Economy
Pablo Monedero, Alfredo Gea, Pedro Castro, Ángel M. Candela-Toha, María L. Hernández-Sanz, Egoitz Arruti, Jesús Villar, Carlos Ferrando, Pablo Monedero, Alfredo Gea, Pedro Castro, Ángel M. Candela-Toha, Marina Vendrell, G. Sánchez‐Etayo, Amalia Alcón, Isabel Belda, Mercè Agustí, Albert Carramiñana, Isabel Gracia, Miriam Panzeri, Irene León, Jaume Balust, Ricard Navarro, M.J. Arguís, María José Carretero, Cristina Ibáñez, Juan Perdomo, Antonio Rezusta López, Manuel López-Baamonde, Tomás Cuñat, Marta Ubré, Antonio Ojeda, Andrea Calvo, Eva Rivas, Paola Hurtado, Roger Pujol, Nuria Hinarejos Martín, J. Tercero, Pepe Sanahuja, Marta Magaldi, Miquel Coca‐Martinez, Elena del Río, Julia Martínez-Ocón, Paula Masgoret, Monserrat Tió, A. Caballero, Raquel Risco, R. Bergé, Lidia Díaz Gómez, Nicolás de Riva, Ana Ruiz, Beatriz Beatriz, Tena, Sebastián Jaramillo, José M. Balibrea, Francisco B. de Lacy, Ana Otero, Ainitze Ibarzábal, Raquel Bravo, Anna Carreras-Castañer, Daniel Martín-Barreda, Alfonso Jesús Alias, Mariano Balaguer-Castro, Jorge Aliaga, Alex Almuedo-Riera, Joan Ramón Alonso, Rut Andrea, Gerard Sergi Angelès, Marilyn Arias, Fátima Aziz, Joan R. Badia, Enric Barbeta, Toni Torres, Guillem Batiste, Pau Benet, X. Borrat, María Borrell, Ernest Bragulat, Inmaculada Carmona, Manuel Castellá, Pedro Castro, Joan Ceravalls, Óscar Comino, Claudia Cucciniello, Clàudia De Deray, O De Diego, Paula De la Matta, Marta Farrero, Javier Fernández, Sara Fernández, Anna Fernández, Miquel Ferrer, Ana Fervienza, María Tallo Forga, Daniel Forné, C Redondo Galán, Andrea Gómez, Eduard Guasch, Maria De Santis, Adriana Jacas, Beltrán Jiménez, Pere Leyes, Teresa López, José Antonio Martínez, Graciela Martínez‐Palli, Jordi Mercadal, Guido Muñoz, José Luís Bernal Muñoz, Ricard Navarro, Josep M. Nicolás, Josè T. Ortiz-Pérez, Anna Peiró, Manuel Avelino Pestano Pérez, Esteban Poch, M Pujol, Eduard Quintana, Bartomeu Ramis, Enric Reverter, Irene Rovira, Pablo Ruiz, Elena Sandoval, Stefan Schneider, Oriol Sibila, Carla Solé, Álex Soriano, Dolors Soy, M. Suárez, Adrián Téllez, David Toapanta, Antoni Torres, Xavier Urra, César Aldecoa, Alicia Bordell, Silvia Martín, Judith Andrés, A. Martínez Ruíz, Gonzalo Tamayo, Iñaki Bilbao Villasante, F. Iturri Clavero, Covadonga Peralta Álvarez, Julia T. Herrera Díez, Andrea García Trancho, Iñaki Sainz Mandiola, Carmen Suárez, Angela Ruiz Bocos, Eneritz Urrutia Izagirre, Pablo Ortiz de Urbina Fernández, Naiara Apodaka López, Leire Prieto Molano, Eunate Ganuza Martínez, Iratxe Vallinas Hidalgo, Karmele de Orte Sancho, Celia González Paniagua, Gemma Ortiz Labrador, Mireia Pérez Larrañaga, Marta López Miguelez, Estíbaliz Bárcena Andrés, Erik Urutxurtu Laureano, María Jesús Maroño Boedo, Blanca Escontrela Rodríguez, Aitziber Ereñozaga Camiruaga, Deiene Lasuen Aguirre, Ainhoa Zabal Maeztu, Ane Guereca Gala, Iker Castelo Korro, Andrés Álvarez Campo, Alejandro Carcelen Viana, Alejandro Alberdi Enríquez, Xabier Ormazábal Rementeria, Alberto Sánchez, Rosa Gutiérrez Rico, Pablo Barbier Damborenea, Marta Guerenabarrena Momeñe, Borja Cuesta Ruiz, Alejandro López Rico, Ana Rojo Polo, Covadonga García Grijelmo, Mikel Celorrio Reta, Eneko Martín Arroyo, Leire Artaza Aparicio, Iñaki Ituarte Aspiazu, Ane Igeregi Basabe, Itxaso Merino Julian, I. Rico, María Paz Martínez, Ramón Adalia Bartolomé, Luigi Zattera, Irina Adalid Hernández, Leire Larrañaga Altuna, Aina Serrallonga Castells, Adriana Vílchez Garcia, María Angélica Rivera Núñez, Lorena Román, Isabel Delgado, Adela Benítez-Cano Martínez, Mireia Chanzá Albert, Juan Carlos Álvarez García, Luis Aguilera Cuchillo, Sandra Beltrán de Heredia, Jesús Carazo Cordobés, Carlos Alberto García Bernedo, Fernando Escolano Villén, Francisco Javier Redondo Calvo, Rubén Villazala González, Víctor Baladrón González, Patricia Faba, Omar Montenegro, Natalia Bejarano, Sergio Marcos Contreras, Alejandro García Rodríguez, Saleta Rey Vázquez, Cristina García Pérez, E. Miguélez, Irene Pérez Blanco, David García Rivera, Ane Martín de la Fuente, Marta Pardo, Vanessa Rodríguez, U. Bengoetxea, F. Ramasco, Sheila Olga Santidrián Bernal, Alvar Santa Cruz Hernando, A. Planas Roca, Carlos Figueroa Yusta, Esther García Villabona, Carmen Vallejo Lantero, Eva Patiño Rodriguez, Alvaro Esquivel Toledo, David Arribas Méndez, Mar Orts Rodriguez, Rosa Méndez Hernández, Jesús Nieves Alonso, Inés Imaz Artazcoz, Sonia Expósito Carazo, Carlos Román Guerrero, Elena Rojo Rodríguez, Ricardo Moreno González, Julia Hernando Santos, Jara Torrente Pérez, Esperanza Mata Mena, Manuel Martı́nez, Enrique Alday Muñoz, Patricia Martín Serrano, Laura Cotter Muñoz, Amadea Mjertan, Diego Gutiérrez Martínez, Carmen Rodríguez García, Olaya Alonso Viejo, Juan Alvarez Pereira, Ana Carmona Bonet, Diana Parrado López, Eva de Dios Tomas, R. Martín Celemín, María Luisa Meilan Paz, Luis Quecedo Gutiérrez, Noemí Diaz Velasco, Gabriel Martin Hernández, Francisco Garcia del Corral, Gloria Hernandez Arias, David Cuesta, Ana Gómez Rice, Encarna Mateos Sevillano, Natalia Olmos Molpeceres, Beatriz Domínguez, Ana Vázquez Lima, A Candela, Ismael A. Acevedo Bambaren, Maria Isabel Albala Blanco, Paloma Alonso Montoiro, Fernando Álvarez Utrera, Juan Avellanosa Esteruelas, Amal Azzam López, Alberto José Balvis Balvis, Tommaso Bardi, María Beltrán Martín, Jacobo Benatar Haserfaty, Alberto Berruezo Camacho, Laura Betolaza Weimer, María del Mar Carbonell Soto, Cristina Seral, Cristina Cerro Zaballos, Elizabeth Claros Llamas, Pilar Coleta Orduna, Ingrid P. Cortes Forero, Pascual Agustín Crespo Aliseda, María Angélica de Pablo Pajares, Yolanda Díez Remesal, Trinidad Dorado Díaz, Noemí Echevarría Blasco, María Elena Elías Martín, Javier Felices Triviño, Natalia Fernández López, Cristina Fernández Martín, Natalia Ferreiro Pozuelo, Luis Gajate Martín, Clara Gallego Santos,
Abstract Background Critically ill patients with coronavirus disease 19 (COVID-19) have a high fatality rate likely due to a dysregulated immune response. Corticosteroids could attenuate this inappropriate response, although there are still some concerns regarding its use, timing, and dose. Methods This is a nationwide, prospective, multicenter, observational, cohort study in critically ill adult patients with COVID-19 admitted into Intensive Care Units (ICU) in Spain from 12th March to 29th June ...
BioMed Central
Jesús Chacín, Pedro Cárdenas, Pablo Lobo, Ileana Hernández,
The effects of pure ethanol and some alcoholic beverages on acid secretion and metabolism were examined in the isolated toad gastric mucosa. Pure ethanol applied to the luminal side or to the submucosal side at low concentrations (2%-10%) was a potent stimulant of acid secretion, whereas high concentrations (greater than or equal to 20%) were inhibitory. Cimetidine and calcium-free solutions did not abolish the secretory effect of ethanol. Beer and wine, but not rum and whisky, caused a significant ...
Tópico(s): Ion Transport and Channel Regulation
1991 - Elsevier BV | Gastroenterology
José C. Fernández‐Alvarez, Iván Hernández López, Pedro Pablo Cruz-Cobas, Taimí Cárdenas-Díaz, A. J. Batista‐Leyva,
Purpose: To determine the capabilities of a multilayer perceptron (MLP) for calculating the power of an intraocular lens (IOL) to be implanted and in achieving a given postoperative stable refraction. Setting: Cuban Institute of Ophthalmology, Havana, Cuba. Design: Retrospective review. Methods: The study comprised data of patients who had uneventful phacoemulsification cataract surgery with implantation of a biconvex acrylic foldable IOL (type RYCF, model Ocuflex) in the capsular bag over 6 years. ...
Tópico(s): Corneal surgery and disorders
2019 - Lippincott Williams & Wilkins | Journal of Cataract & Refractive Surgery
Elena Bonzón‐Kulichenko, Daniel Pérez-Hernández, Estefanía Núñez, Pablo Martínez-Acedo, Pedro Navarro, Marco Trevisán-Herraz, María C. Ramos, Saleta Sierra, Sara Martı́nez-Martı́nez, Marisol Ruiz‐Meana, Elizabeth Miró-Casas, David García‐Dorado, Juan Miguel Redondo, Javier S. Burgos, Jesús Vázquez,
MS-based quantitative proteomics plays an increasingly important role in biological and medical research and the development of these techniques remains one of the most important challenges in mass spectrometry. Numerous stable isotope labeling approaches have been proposed. However, and particularly in the case of 18O-labeling, a standard protocol of general applicability is still lacking, and statistical issues associated to these methods remain to be investigated. In this work we present an improved ...
Tópico(s): Cancer, Hypoxia, and Metabolism
2010 - Elsevier BV | Molecular & Cellular Proteomics
José Luis Esquinas Requena, Inmaculada García-Nogueras, Pablo Hernández-Zegarra, Pilar Atienzar‐Núñez, Pedro Manuel Sánchez‐Jurado, Pedro Abizanda,
El objetivo de este trabajo fue examinar la prevalencia de anemia según el estado de fragilidad y analizar la relación entre anemia, concentración de hemoglobina y estado de fragilidad en una cohorte de ancianos españoles. Subestudio transversal de la cohorte FRADEA (Fragilidad y Dependencia en Albacete), un estudio de cohorte concurrente de base poblacional realizado en mayores de 69 años de Albacete (España). De los 993 participantes incluidos en la primera oleada, se seleccionaron 790 sujetos con ...
Tópico(s): Dialysis and Renal Disease Management
2021 - Elsevier BV | Revista Española de Geriatría y Gerontología
Susana Sánchez Orgaz, Martín Pedemonte, Pablo Ezzatti, Pedro Curto-Risso, A. Medina, A. Calvo Hernández,
A multi-objective and multi-parametric optimization analysis is presented for a recuperative multi-step solar-driven Brayton thermosolar plant. The analysis is done over a thermodynamic analytical model that incorporates all the losses observed in real plants, from the heat engine itself and from the solar subsystem. The model allows to consider several compression–expansion stages. The overall system efficiency and the power output were taken as objective functions. The Pareto Front of the system ...
Tópico(s): Advanced Thermodynamics and Statistical Mechanics
2015 - Elsevier BV | Energy Conversion and Management