Produção Nacional
Revisado por pares
Pedro Miguel Ocampos Pedroso, Pedro Soares Bezerra Júnior, Caroline Argenta Pescador, André Gustavo Cabrera Dalto, Giovana Rosa da Costa, Daniela Isabel Brayer Pereira, Jânio Morais Santúrio, David Driemeier,
Descrevem-se cinco casos de pitiose cutânea em equinos enviados ao Laboratório de Patologia Veterinária da Universidade Federal do Rio Grande do Sul, Brasil. Microscopicamente focos necróticos circundados por infiltrados de eosinófilos, neutrófilos, macrófagos e abundante tecido conjuntivo fibroso foi observado. Filamentos de hifas esparsamente septadas foram identificadas no centro das áreas necróticas. Na coloração de prata metenamina de Grocott hifas septadas, ramificadas foram também observadas ...
Tópico(s): Tumors and Oncological Cases
2018 - UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL | ACTA SCIENTIAE VETERINARIAE
Leonardo Pedroso, Pedro Batista,
Signal control strategies for congested urban road networks designed in a centralized framework require many communication links, serious processing power, and infrastructure for the centralized coordination. As a result, strategies based on a centralized framework are not scalable. The use of decentralized signal control strategies for large-scale urban traffic networks is a solution to this problem, since it allows for the implementation of such strategies on networks whose centralized solution ...
Tópico(s): Traffic Prediction and Management Techniques
2021 - Elsevier BV | Transportation Research Part C Emerging Technologies
Produção Nacional
Revisado por pares
Ricardo Keiichi Nakazato, Marisia Pannia Esposito, Poliana Cardoso‐Gustavson, Patrícia Bulbovas, Andrea Nunes Vaz Pedroso, Pedro Ivo Lembo Silveira de Assis, Marisa Domingos,
Tópico(s): Heavy Metals in Plants
2018 - Springer Science+Business Media | Environmental Science and Pollution Research
Produção Nacional
Revisado por pares
José Luiz Pedroso, Pedro Braga‐Neto, Alberto Martínez, Carlos Roberto Martins, Flávio Moura Rezende Filho, Manoel Alves Sobreira-Neto, Lucila Bizari Fernandes do Prado, Gilmar Fernandes do Prado, Marcondes C. França, Orlando Graziani Póvoas Barsottini,
This article provides a description on clinical features and pathophysiology of the main sleep disorders observed in Machado-Joseph disease (MJD).Pathological studies have clearly demonstrated that degenerative process in MJD is widespread in the nervous system, and not restricted to the cerebellum. Nonmotor manifestations are frequent and may include pain, cramps, dysautonomia, cognitive deficits, psychiatric manifestations, olfactory deficits, fatigue, nutritional issues, and sleep disorders.Sleep ...
Tópico(s): Restless Legs Syndrome Research
2016 - Lippincott Williams & Wilkins | Current Opinion in Psychiatry
Denis Rafael Pedroso, Pedro de S. Castanheira, Renner Luiz Cerqueira Baptista,
Diplura C.L. Koch, 1850 is a mygalomorph genus with putative records from Central and South America. The type-species Diplura macrura (C.L. Koch, 1841), originally described from West Indies, is poorly known and represented only by its holotype. Most of the 20 species currently included in the genus lack modern taxonomic descriptions, as D. lineata (Lucas, 1857), from Rio de Janeiro state, Brazil. Males and females of Diplura macrura and D. lineata are herein redescribed. New junior synonyms of D. ...
Tópico(s): Lepidoptera: Biology and Taxonomy
2016 - Consortium of European Natural History Museums | European Journal of Taxonomy
Produção Nacional
Revisado por pares
José Luiz Pedroso, Pedro Braga‐Neto, Marcio Luiz Escorcio‐Bezerra, Agessandro Abrahão, Marcus Vinicius Cristino Albuquerque, Flávio Moura Rezende Filho, Paulo Victor Sgobbi de Souza, Wladimir Bocca Vieira de Rezende Pinto, Franklin Roberto Pereira Borges, Maria Luiza Saraiva Pereira, Laura Bannach Jardim, Orlando Graziani Póvoas Barsottini,
Tópico(s): Parkinson's Disease Mechanisms and Treatments
2016 - Springer Science+Business Media | The Cerebellum
Produção Nacional
Revisado por pares
Agessandro Abrahão, José Luiz Pedroso, Pedro Braga‐Neto, Edson Bor‐Seng‐Shu, Patrícia de Carvalho Aguiar, Orlando Graziani Póvoas Barsottini,
Tópico(s): Parkinson's Disease Mechanisms and Treatments
2015 - Springer Science+Business Media | Neurogenetics
Produção Nacional
Revisado por pares
Carolina Yuri P. Aizawa, José Luiz Pedroso, Pedro Braga‐Neto, Marilia Rezende Callegari, Orlando Graziani Póvoas Barsottini,
OBJECTIVES: To assess balance and ability to function in patients with spinocerebellar ataxia. METHODS: A total of 44 patients with different spinocerebellar ataxia types 1, 2, 3, and 6 were evaluated using the Tinetti balance and gait assessment and the functional independence measure. The scale for the assessment and rating of ataxia and the international cooperative ataxia rating scale were used to evaluate disease severity. RESULTS: Most patients showed significant risk of falls. The balance ...
Tópico(s): Trace Elements in Health
2013 - Thieme Medical Publishers (Germany) | Arquivos de Neuro-Psiquiatria
Produção Nacional
Revisado por pares
José Luiz Pedroso, Pedro Braga‐Neto, Paulo Victor Sgobbi de Souza, Orlando Graziani Póvoas Barsottini,
Sir, We have read with great interest the article by Wu and Hallett (2013) entitled ‘The cerebellum in Parkinson’s disease’. These authors reviewed related anatomical, clinical and neurophysiological findings, and discuss the possible roles of the cerebellum in the pathophysiology of Parkinson’s disease. They pointed out that Parkinson’s disease is associated with pathological and structural changes in the cerebellum, and also stated that functional neuroimaging has demonstrated increased activation ...
Tópico(s): Parkinson's Disease Mechanisms and Treatments
2013 - Oxford University Press | Brain
Produção Nacional
Revisado por pares
José Luiz Pedroso, Pedro Braga‐Neto, João Radvany, Orlando Graziani Póvoas Barsottini,
Machado-Joseph disease is an autosomal dominant inherited disorder of Azorean ancestry firstly described in 1972. Since then, several Brazilian researchers have studied clinical and genetic issues related to the disease. Nowadays, Machado-Joseph disease is considered the most common spinocerebellar ataxia worldwide. Machado-Joseph disease still has no specific therapy to arrest progression, but the unclear pathophysiological mechanism, features related to genetic characteristics, phenotype variability, ...
Tópico(s): Parkinson's Disease Mechanisms and Treatments
2012 - Thieme Medical Publishers (Germany) | Arquivos de Neuro-Psiquiatria
Produção Nacional
Revisado por pares
José Luiz Pedroso, Pedro Braga‐Neto, André C. Felício, Thaı́s Minett, Elton Yamaguchi, Lucila Bizari Fernandes do Prado, Luciane Bizari Coin de Carvalho, Lívia Almeida Dutra, Marcelo Q. Hoexter, Antônio José da Rocha, Rodrigo A. Bressan, Gilmar Fernandes do Prado, Orlando Graziani Póvoas Barsottini,
Objectives Sleep disorders, especially restless legs syndrome (RLS) and rapid eye movement sleep behavior disorder (RBD), are common in spinocerebellar ataxia type 3 or Machado–Joseph disease (MJD), and a possible underlying dopaminergic dysfunction is implicated. This study assessed the relationship between sleep disorders in MJD and dopamine transporter (DAT) densities. Patients and methods Twenty-two patients with MJD and twenty healthy subjects were enrolled in this study. MJD patients underwent ...
Tópico(s): Neurological disorders and treatments
2012 - Elsevier BV | Journal of the Neurological Sciences
Produção Nacional
Revisado por pares
José Luiz Pedroso, Pedro Braga‐Neto, Lívia Almeida Dutra, Orlando Graziani Póvoas Barsottini,
Universidade Federal de Sao Paulo (UNIFESP) Division of General Neurology and Ataxias Department of Neurology and Neurosurgery
Tópico(s): Diabetes and associated disorders
2011 - Thieme Medical Publishers (Germany) | Arquivos de Neuro-Psiquiatria
Produção Nacional
Revisado por pares
José Luiz Pedroso, Pedro Braga‐Neto, André C. Felício, Lívia Almeida Dutra, William Adolfo Celso dos Santos, Gilmar Fernandes do Prado, Orlando Graziani Póvoas Barsottini,
Tópico(s): Genetic Neurodegenerative Diseases
2011 - Springer Science+Business Media | The Cerebellum
Produção Nacional
Revisado por pares
José Luiz Pedroso, Pedro Braga‐Neto, André C. Felício, Camila C. Aquino, Lucila Bizari Fernandes do Prado, Gilmar Fernandes do Prado, Orlando Graziani Póvoas Barsottini,
Cerebellar ataxias comprise a wide range of etiologies leading to central nervous system-related motor and non-motor symptoms. Recently, a large body of evidence has demonstrated a high frequency of non-motor manifestations in cerebellar ataxias, specially in autosomal dominant spinocerebellar ataxias (SCA). Among these non-motor dysfunctions, sleep disorders have been recognized, although still under or even misdiagnosed. In this review, we highlight the main sleep disorders related to cerebellar ...
Tópico(s): Neurological disorders and treatments
2011 - Thieme Medical Publishers (Germany) | Arquivos de Neuro-Psiquiatria
Produção Nacional
Revisado por pares
José Luiz Pedroso, Pedro Braga‐Neto, Agessandro Abrahão, René Leandro Magalhães Rivero, C. Abdalla, Nitamar Abdala, Orlando Graziani Póvoas Barsottini,
Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a neurodegenerative disorder characterized by late-infantile onset spastic ataxia and other neurological features. ARSACS has a high prevalence in northeastern Quebec, Canada. Several ARSACS cases have been reported outside Canada in recent decades. This is the first report of typical clinical and neuroimaging features in a Brazilian family with probable diagnosis of ARSACS.
Tópico(s): Neurological diseases and metabolism
2011 - Thieme Medical Publishers (Germany) | Arquivos de Neuro-Psiquiatria
Produção Nacional
Revisado por pares
João A.B. Pedroso, Pedro Omori Ribeiro de Mendonça, Marco Aurélio Salomão Fortes, Igor Tomaz, Vitor L Pecorali, Thais Barabba Auricino, Ismael Cabral Costa, Leandro B. Lima, Isadora C. Furigo, Debora N Bueno, Angela M. Ramos-Lobo, Claudimara Ferini Pacicco Lotfi, José Donato,
Many hormones/cytokines are secreted in response to exercise and cytokine signaling may play a pivotal role in the training adaptations. To investigate the importance of cytokine signaling during vertical ladder climbing, a resistance exercise model, we produced mice lacking SOCS3 protein exclusively in steroidogenic factor-1 (SF1) cells (SF1 Socs3 KO mice). SF1 expression is found in steroidogenic cells of the adrenal cortex and gonads, as well as in neurons of the ventromedial nucleus of the hypothalamus. ...
Tópico(s): Adipose Tissue and Metabolism
2017 - Bioscientifica | Journal of Endocrinology
Produção Nacional
Revisado por pares
Diogo Fernandes dos Santos, José Luiz Pedroso, Pedro Braga‐Neto, Giselle Melo Fontes Silva, Luciane Bizari Coin de Carvalho, Lucila Bizari Fernandes do Prado, Orlando Graziani Póvoas Barsottini, Gilmar Fernandes do Prado,
Machado-Joseph disease (MJD) is a neurodegenerative disease which usually presents several clinical findings including cerebellar ataxia and other extracerebellar features, such as Parkinsonism, dystonia, peripheral neuropathy, and lower motor neuron disease. Some data have demonstrated a high frequency of sleep disorders in these patients, including excessive daytime sleepiness (EDS), insomnia, obstructive sleep apnea (OSA), rapid eye movement (REM) sleep behavior disorder (RBD), and restless legs syndrome ( ...
Tópico(s): Glycogen Storage Diseases and Myoclonus
2014 - Elsevier BV | Sleep Medicine
Pedro Rodrigues, Vanda Pedroso, João Pedro Gouveia, Samuel C. V. Martins, Carlos M. Lopes, Isabel Alves,
In this study, the influence of soil and atmosphere conditions on noon and basal leaf water potential of vines "Touriga Nacional" in the Dão region submitted to different irrigation treatments is analysed. Both indicators showed to be dependent on environmental conditions at the time of measurement. Leaf water potential at noon of fully watered plants was linearly related with atmospheric conditions, with values registered when vapour pressure deficit (VPD) was higher than approximately 3 kPa being ...
Tópico(s): Plant Physiology and Cultivation Studies
2012 - Springer Science+Business Media | Irrigation Science
Produção Nacional
Revisado por pares
Marcus Vinicius Cristino Albuquerque, José Luiz Pedroso, Pedro Braga Neto, Orlando Graziani Póvoas Barsottini,
The spinocerebellar ataxias (SCA) are a group of neurodegenerative disorders characterized by heterogeneous clinical presentation. Spinocerebellar ataxia type 7 (SCA7) is caused by an abnormal CAG repeat expansion and includes cerebellar signs associated with visual loss and ophthalmoplegia. Marked anticipation and dynamic mutation is observed in SCA7. Moreover, phenotype variability and very early onset of symptoms may occur. In this article, a large series of Brazilian patients with different SCA ...
Tópico(s): DNA Repair Mechanisms
2015 - Thieme Medical Publishers (Germany) | Arquivos de Neuro-Psiquiatria
Marco Silva, João Pedro Pedroso, Ana Viana,
We study a setting in which a company not only has a fleet of capacitated vehicles and drivers available to make deliveries but may also use the services of occasional drivers (ODs) willing to make deliveries using their own vehicles in return for a small fee. Under such a business model, a.k.a crowdshipping, the company seeks to make all the deliveries at the minimum total cost, i.e., the cost associated with their vehicles plus the compensation paid to the ODs. We consider a stochastic and dynamic ...
Tópico(s): Urban and Freight Transport Logistics
2023 - Springer Science+Business Media | EURO Journal on Transportation and Logistics
Miguel Barbosa, João Pedro Pedroso, Ana Viana,
A recent relevant innovation in last-mile delivery is to consider the possibility of goods being delivered by couriers appointed through crowdsourcing. In this paper we focus on the setting of in-store customers delivering goods, ordered by online customers, on their way home. We assume that not all the proposed delivery tasks will necessarily be accepted, and use logistic regression to model the crowd agents' willingness to undertake a delivery. This model is then used to build a novel compensation ...
Tópico(s): Sharing Economy and Platforms
2022 - Elsevier BV | Computers & Operations Research
Produção Nacional
Revisado por pares
André Gustavo dos Santos, Ana Viana, João Pedro Pedroso,
We propose a new approach for the lastmile delivery problem where, besides serving as collecting points of orders for customers, parcel lockers are also used as transshipment nodes in a 2-echelon delivery system. Moreover, we consider that a customer (occasional courier) visiting a locker may accept a compensation to make a delivery to another customer on their regular traveling path. The proposed shared use of the locker facilities – by customers that prefer to self-pick up their orders, and also ...
Tópico(s): Advanced Manufacturing and Logistics Optimization
2022 - Elsevier BV | Transportation Research Part E Logistics and Transportation Review
Alberto Santini, Ana Viana, Xenia Klimentova, João Pedro Pedroso,
We study a variant of the Probabilistic Travelling Salesman Problem arising when retailers crowdsource last-mile deliveries to their own customers, who can refuse or accept in exchange for a reward. A planner must identify which deliveries to offer, knowing that all deliveries need fulfilment, either via crowdsourcing or using the retailer's own vehicle. We formalise the problem and position it in both the literature about crowdsourcing and among routing problems in which not all customers need ...
Tópico(s): Transportation Planning and Optimization
2022 - Elsevier BV | Computers & Operations Research
Margarida Carvalho, Andrea Lodi, João Pedro Pedroso,
The recently-defined class of integer programming games (IPG) models situations where multiple self-interested decision makers interact, with their strategy sets represented by a finite set of linear constraints together with integer requirements. Many real-world problems can suitably be cast in this way, hence anticipating IPG outcomes is of crucial value for policy makers. Nash equilibria have been widely accepted as the solution concept of a game. Thus, their computation provides a reasonable ...
Tópico(s): Game Theory and Voting Systems
2022 - Elsevier BV | European Journal of Operational Research
Xenia Klimentova, Ana Viana, João Pedro Pedroso, Nicolau Santos,
Nowadays there are several countries running independent kidney exchange programmes (KEPs). These programmes allow a patient with kidney failure, having a willing healthy but incompatible donor, to receive a transplant from a similar pair where the donor is compatible with him. Since in general larger patient-donor pools allow for more patients to be matched, this prompts independent programmes (agents) to merge their pools and collaborate in order to increase the overall number of transplants. Such ...
Tópico(s): Blood donation and transfusion practices
2020 - Elsevier BV | Omega
Produção Nacional
Revisado por pares
Roberto Júnio Pedroso Dias, Pedro Mendes de Souza, Mariana Fonseca Rossi, Alfredo Hannemann Wieloch, Inácio Domingos da Silva‐Neto, Marta D’Agosto,
The aim of our study was to evaluate the water quality of an urban stream in southeastern Brazil by analyzing epibenthic ciliates, and to investigate the existence of phylogenetic signal for saprobity in ciliates. However, before conducting this type of phylogenetic study, it is necessary to evaluate if the saprobic classification used frequently in the northern Hemisphere is suitable for neotropical ecosystems. Sediment samples were collected from five sampling stations: two in rural areas and ...
Tópico(s): Genomics and Phylogenetic Studies
2020 - Elsevier BV | Environmental Pollution
Katarzyna Gdowska, Ana Viana, João Pedro Pedroso,
For the predicted growth of e-commerce, supply chains need to adapt to new conditions, so that delivery can be fast, cheap and reliable. The key to success is the last-mile product delivery (LMD) – the last stage of the supply chain, where the ordered product is delivered to the final consumer's location. One innovative proposal puts foundations in a new delivery model where a professional delivery fleet (PF) is supplemented partially or fully with crowdshipping. The main idea of crowdshipping is to ...
Tópico(s): Sharing Economy and Platforms
2018 - Elsevier BV | Transportation research procedia
Nicolau Santos, Paolo Tubertini, Ana Viana, João Pedro Pedroso,
One of the challenges in a kidney exchange program (KEP) is to choose policies that ensure an effective and fair management of all participating patients. In order to understand the implications of different policies of patient allocation and pool management, decision makers should be supported by a simulation tool capable of tackling realistic exchange pools and modeling their dynamic behavior. In this paper, we propose a KEP simulator that takes into consideration the wide typology of actors found ...
Tópico(s): Hemoglobinopathies and Related Disorders
2017 - Palgrave Macmillan | Journal of the Operational Research Society
This paper proposes a method for computing the expectation for the length of a maximum set of vertex-disjoint cycles in a digraph where vertices and/or arcs are subject to failure with a known probability. This method has an immediate practical application: it can be used for the solution of a kidney exchange program in the common situation where the underlying graph is unreliable. Results for realistic benchmark instances are reported and analyzed.
Tópico(s): Optimization and Search Problems
2014 - Springer Science+Business Media | Lecture notes in computer science
Dewan Fayzur Rahman, Ana Viana, João Pedro Pedroso,
This paper presents two new solution approaches capable of finding optimal solutions for the thermal unit commitment problem in power generation planning. The approaches explore the concept of “matheuristics”, a term usually used to refer to an optimization algorithm that hybridizes (meta)heuristics with mixed integer programming solvers, in order to speed up convergence to optimality for large scale instances. Two algorithms are proposed: “local branching”, and an hybridization of particle swarm optimization ...
Tópico(s): Power System Reliability and Maintenance
2014 - Elsevier BV | International Journal of Electrical Power & Energy Systems