Andrew Robson, Jennifer Pothecary, David Sharrock and Adam LeBor, David Townsend, David Whitter, Andrew Billen, Matthew Syed, Catherine Riley, DJM, Malathy Sitaram, Anne Spackman, Ian Nathan, Sarah Potter, Gary Duncan, Peter Lansley, Robert Thicknesse, Paul Hoggart, Mark Souster, Richard Hobson, Ivo Tennant, Michael Evans Defence Editor, R. J. K. Cassels, Philip Howard, Hilary Finch, David Chater, Nic Hopkins, Clive Davis, Alexandra Frean Social Affairs Correspondent, Chris Bowers, Elizabeth Judge, Jeremy Whittle, Laszlo Heckenast, Kevin Eason, James Eve, Raymond Snoddy, Andrew Norfolk, David Sharrock, Roger Sexton, Valerie Elliott Countryside Editor, David McVay, Valerie Elliott, Thrasy Petropoulos, Jennai Cox Fitness Editor, Anthony Browne, Andrew McLuskey, Tom Bawden, Gary Jacob, Joe Morgan, Hilton Dawson, David Hinchliffe (MP), Joyce Quin (MP), Robert F. Chamberiam, Ruth Gledhill Religion Correspondent, Dalya Alberge Arts Correspondent, Dan Sabbagh, Oliver Del Mar, Phoebe Greenwood, Nicholas Blanford, Lisa Kagan, Roland Watson, Michael Marland, David Hands, Alyson McLaren, Mark Pougatch, Bryan Storey, Mark Court, Anthony Hollis, Russell Kempson, Roland Watson and Elaine Monaghan, Daniel McGrory, Oliver Kay, Ronan McGreevy, Tom Ruben, Frank Skinner, John Westerby, Neil Harman, Rick Broadbent, Jill Sherman Whitehall Editor, David Lawrenson, John Hopkins Golf Correspondent, Chris Patten, Gabriel Rozenberg, Neil Harman Tennis Correspondent, David Powell Athletics Correspondent, Marcus Binney, Raymond Keene, Richard Abbott, Oliver Impey, Matthew Pryor, John Russell Taylor, Geoff Biddulph, Sean MacAulay, Matt Dickinson, Christine Buckley Industrial Editor, Gary Rathbone, Chris Campling, Russell Hotten, Alan Pavelin, Cathy Harris, Helen Nugent, Christopher Martin-Jenkins Chief Cricket Correspondent, Mick Hume, Roger Boyes, Emily Davies, Nick Kelly, Dalya Alberge, David Hands Rugby Correspondent, Tom Dart, Glen Owen, Andrew Clennell, William Rees-Mogg, Dominic Kennedy, Anne Ashworth, Nick Szczepanik, Melissa Kite Political Correspondent, Tim Hames, Ashling O'connor, Graham Searjeant Financial Editor, Philip Davies, Max Davidson, Mike Rosewell, Chris McGrath, Glen Owen Education Correspondent, Robert Tait, Walter Gammie, Lea Paterson Economics Editor, Brian Glanville, Michael Dynes, Gary Duncan Economics Correspondent, Mark Henderson, Richard Laming, Director, Chris Ayres, Alan Rice, Martin Waller, AnselmKuhn, Carl Mortished International Business Editor, David Carlisle, Eric Brown, James Jackson, Daniel Rosenthal, Stephen Dalton, Stephen Gardiner, Leo Lewis, Richard Morrison, Alyson Rudd, David Powell, James Christopher, Bill Edgar, Andrew Bailey, Adam Sherwin, P. Glaister, Alan Lee Racing Correspondent, Brian Dixon, Edward Gorman Sailing Correspondent, Tim Johnston, Philip Webster and Melissa Kite, Christopher Irvine, Scott Fitzgerald, Lawrie Browniee,
... to You, Mate Frankskinner Forget Strach, super cool Pires wooed my aliegiances at the zebra crossing Winticketstothenuropeancupfinal ...
2003 - Gale Group | TDA
J. M. Ayres, T. H. Clutton‐Brock,
... Kenney, Marcelo J. Sturaro, Teresa C. S. Ávila‐Pires, Pedro L. V. Peloso, Miguel T. Rodrigues, L. Lacey ...
Tópico(s): Fish biology, ecology, and behavior
1992 - University of Chicago Press | The American Naturalist
Produção Nacional
Revisado por pares
Lays Cordeiro Guimarães, Pedro Augusto Carvalho Costa, Sérgio Scalzo, Heloísa Athaydes Seabra Ferreira, Ana Carolina Soares Braga, Leonardo Camilo de Oliveira, Maria Marta Figueiredo, Sarah J. Shepherd, Alex G. Hamilton, Celso Martins Queiroz‐Junior, Walison N. Silva, Natália Jordana Alves da Silva, Marco Túllio Rodrigues Alves, Anderson K. Santos, Kevin Kelton Santos de Faria, Fernanda Martins Marim, Heidge Fukumasu, Alexander Birbrair, Andréa Teixeira‐Carvalho, Renato Santana Aguiar, Michael J. Mitchell, Mauro Martins Teixeira, Vivian Vasconcelos Costa, Frédéric Frézard, Pedro Pires Goulart Guimarães,
Abstract A safe and effective vaccine with long-term protection against SARS-CoV-2 variants of concern (VOCs) is a global health priority. Here, we develop lipid nanoparticles (LNPs) to provide safe and effective delivery of plasmid DNA (pDNA) and show protection against VOCs in female small animal models. Using a library of LNPs encapsulating unique barcoded DNA (b-DNA), we screen for b-DNA delivery after intramuscular administration. The top-performing LNPs are further tested for their capacity of ...
Tópico(s): RNA Interference and Gene Delivery
2024 - Nature Portfolio | Nature Communications
Produção Nacional
Revisado por pares
Pedro H. D. M. Prazeres, Heloísa Athaydes Seabra Ferreira, Pedro Augusto Carvalho Costa, Walison da Silva, Marco Túllio Rodrigues Alves, Marshall S. Padilla, Ajay S. Thatte, Anderson K. Santos, Anderson Oliveira Lobo, Adriano de Paula Sabino, Helen L. Del Puerto, Michael J. Mitchell, Pedro Pires Goulart Guimarães,
Chimeric antigen receptor (CAR) cell therapy represents a hallmark in cancer immunotherapy, with significant clinical results in the treatment of hematological tumors. However, current approved methods to engineer T cells to express CAR use viral vectors, which are integrative and have been associated with severe adverse effects due to constitutive expression of CAR. In this context, non-viral vectors such as ionizable lipid nanoparticles (LNPs) arise as an alternative to engineer CAR T cells with ...
Tópico(s): Virus-based gene therapy research
2023 - Dove Medical Press | International Journal of Nanomedicine
Produção Nacional
Revisado por pares
Glaydson José da Silva, Pedro Paulo A. Funari, Renata Senna Garraffoni,
... com o aporte de formadores como Francisco Murari Pires, Pedro Paulo Abreu Funari e José Antônio Dabdab Trabulsi. ...
Tópico(s): History, Culture, and Diplomacy
2020 - National History Association | Revista Brasileira de História
Produção Nacional
Revisado por pares
Pedro Pires, Mayra Pereira, Luiz Henrique de Araújo Machado, Fernando Bonilla‐Musoles,
... 3-Dimensional Sonography and Sonographically Guided Aspiration Pedro Pires MD, PhD, Pedro Pires MD, PhD Serviço de Medicina Fetal, Centro ... Search for more papers by this author Pedro Pires MD, PhD, Pedro Pires MD, PhD Serviço de Medicina Fetal, Centro Integrado ...
Tópico(s): Fetal and Pediatric Neurological Disorders
2006 - Wiley | Journal of Ultrasound in Medicine
Ricardo Passos, Ana Patrícia Correia, Damiana Pires, Pedro Pires, Inês Ferreira, Marco Simões, Beatriz do Carmo, Paulo Santos, Ana Pombo, Clélia Afonso, Teresa Baptista,
Seaweeds still possess a large undisclosed potential, mainly due to their constituent's richness, which may have several uses for society. In aquaculture, they may play a role as an ecological sustainable aquafeed supplement to increase overall health and fight pathogenic outbreaks. This study aimed to evaluate the general health modulation that the inclusion of Gracilaria gracilis could accomplish in the diet of Dicentrarchus labrax. Dried algae at 2.5% and 5% and algal extract at 0.35% inclusion ...
Tópico(s): Marine and Coastal Ecosystems
2021 - Elsevier BV | Fish & Shellfish Immunology
Produção Nacional
Revisado por pares
Walison da Silva, Pedro Augusto Carvalho Costa, Sérgio Ricardo Scalzo Júnior, Heloísa Athaydes Seabra Ferreira, Pedro H. D. M. Prazeres, Caroline Campos, Marco Túllio Rodrigues Alves, Natália Jordana Alves da Silva, Ana Luiza de Castro Santos, Lays Cordeiro Guimarães, Maria Eduarda Ferris, Ajay S. Thatte, Alex G. Hamilton, Kelly Bicalho, Anderson Oliveira Lobo, Helton C. Santiago, Lucíola S. Barcelos, Maria Marta Figueiredo, Mauro Martins Teixeira, Vivian Vasconcelos Costa, Michael J. Mitchell, Frédéric Frézard, Pedro Pires Goulart Guimarães,
Introduction: Immunotherapy has revolutionized cancer treatment by harnessing the immune system to enhance antitumor responses while minimizing off-target effects. Among the promising cancer-specific therapies, tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has attracted significant attention. Methods: Here, we developed an ionizable lipid nanoparticle (LNP) platform to deliver TRAIL mRNA (LNP-TRAIL) directly to the tumor microenvironment (TME) to induce tumor cell death. Our LNP-TRAIL ...
Tópico(s): Phagocytosis and Immune Regulation
2024 - Dove Medical Press | International Journal of Nanomedicine
Pedro Pires, João Pedro Pereira, Luís F. Martins,
Abstract We study the empirical determinants of Credit Default Swap (CDS) spreads through quantile regressions. In addition to traditional variables, such as implied volatility, put skew, historical stock return, leverage, profitability, and ratings, the results indicate that CDS premiums are strongly determined by CDS illiquidity costs, measured by absolute bid‐ask spreads. The quantile regression approach reveals that high‐risk firms are more sensitive to changes in the explanatory variables that ...
Tópico(s): Financial Distress and Bankruptcy Prediction
2013 - Wiley | European Financial Management
Pedro Pires, João Pedro Pereira, Luís F. Martins,
We study the determinants of Credit Default Swap (CDS) spreads through quantile regressions. The results indicate that CDS spreads are strongly determined not only by traditional theoretical variables, such as the implied volatility and put skew, but also by illiquidity costs. However, contrary to stocks or bonds, we show that CDS transaction costs should be measured by absolute, rather than relative, bid-ask spreads. The quantile regressions reveal significant heterogeneity in the response of low- ...
Tópico(s): Financial Distress and Bankruptcy Prediction
2010 - RELX Group (Netherlands) | SSRN Electronic Journal
Produção Nacional
Revisado por pares
Paulo R. Guimarães, Mathias M. Pires, Pedro Jordano, Jordi Bascompte, John N. Thompson,
Tópico(s): Insect and Arachnid Ecology and Behavior
2017 - Nature Portfolio | Nature
Produção Nacional
Revisado por pares
Mauro Galetti, Alexandra S. Pires, Pedro H. S. Brancalion, Fernando A. S. Fernandez,
Abstract Defaunation has a major driver of biodiversity loss in tropical forests. Here we discuss how to reverse defaunation by re‐introducing key species in defaunated or restored forests.
Tópico(s): Conservation, Biodiversity, and Resource Management
2016 - Wiley | Biotropica
Produção Nacional
Revisado por pares
RES Pires, Pedro José Labronici, Vincenzo Giordano, Kodi Edson Kojima, Maurício Kfuri, M. Barbisan, André Wajnsztejn, Map de Andrade,
During pregnancy, high progesterone and relaxin levels produce physiological ligament relaxation on the pelvis. Therefore, moderate pubic symphysis and sacroiliac joints relaxing provide birth canal widening, thereby facilitating vaginal delivery. Sometimes, functional pain or pelvic instability may occur during pregnancy or puerperium, which is defined as symptomatic pelvic girdle relaxation. In rare cases, a pubic symphysis disruption can occur during the labor, causing severe pain and functional ...
Tópico(s): Spine and Intervertebral Disc Pathology
2015 - Medknow | Annals of Medical and Health Sciences Research
Rita B. Restani, João Conde, Rita F. Pires, Pedro Martins, Alexandra R. Fernandes, Pedro V. Baptista, Vasco D. B. Bonifácio, Ana Aguiar‐Ricardo,
The design and preparation of highly efficient drug delivery platforms using green methodologies is at the forefront of nanotherapeutics research. POxylated polyurea dendrimers are efficiently synthesized using a supercritical-assisted polymerization in carbon dioxide. These fluorescent, pH-responsive and water-soluble core-shell smart nanocarriers show low toxicity in terms of cell viability and absence of glutathione depletion, two of the major side effect limitations of current vectors. The materials ...
Tópico(s): Polymer Surface Interaction Studies
2015 - Wiley | Macromolecular Bioscience
Produção Nacional
Revisado por pares
Danil Yurievich Pimenov, Leonardo Rosa Ribeiro da Silva, Álisson Rocha Machado, Pedro Henrique Pires França, Giuseppe Pintaúde, Deepak Rajendra Unune, Mustafa Kuntoğlu, Grzegorz Królczyk,
Superalloys find widespread application in demanding environments owing to their robust strength and high resistance to heat and corrosion. Nonetheless, these very attributes render them difficult-to-cut materials. Enhancing machinability necessitates effective lubrication and cooling techniques, the efficacy of which varies depending on the specific alloy, manufacturing methodology, and machining conditions. This exhaustive review presents a fresh analysis elucidating the impact of diverse cooling/ ...
Tópico(s): Advanced Machining and Optimization Techniques
2024 - Elsevier BV | Tribology International
Produção Nacional
Revisado por pares
Priscila Oliveira de Souza, Vanderleia Sinhor, Marcelo Guerreiro Crizel, Natanael Pires, Pedro José Sanches Filho, Rochele S. Picoloto, Fábio A. Duarte, Cláudio M. P. Pereira, Márcia F. Mesko,
Microorganisms have been considered as an alternative for bioremediation of contaminated water, and they are naturally available in the environment. This work evaluated the potential of cyanobacteria for bioremediation of chromium (Cr) and lead (Pb) from wastewater obtained from chemistry laboratories. Cell density and total cyanobacterium biomass were evaluated during 240 h to compare the growth in the control medium and the water contaminated by heavy metals, as well as the lethal concentration ...
Tópico(s): Algal biology and biofuel production
2022 - Elsevier BV | Bioresource Technology Reports
Maria João Primitivo, Marta Neves, Cristiana L. Pires, Pedro F. Cruz, Catarina Brito, Ana Cristina Rodrigues, Carla C. C. R. de Carvalho, Megan M. Mortimer, Maria João Moreno, Rui M. M. Brito, Edward J. Taylor, Stefan H. Millson, Fernando H. Reboredo, Maria Jorge Campos, Daniela C. Vaz, Vânia Ribeiro,
Helichrysum italicum (H. italicum) is a halophyte shrub with bright yellow flowers with a strong curry-like aroma. The essential oils of H. italicum have been used in the production of cosmetics and pharmaceuticals, due to their antiallergic and anti-inflammatory properties. In the agri-food sector, H. italicum flowers can be used for seasoning and flavoring food, and as natural food preservatives. Here, we report on the composition, bioactive compounds, and nutritive value of H. italicum flowers. ...
Tópico(s): Plant biochemistry and biosynthesis
2022 - Elsevier BV | Food Research International
Duarte Pimentel, Juliana Serras Pires, Pedro Almeida,
Purpose The purpose of this paper is to explore differences between non-family employees of family and non-family firms regarding the perceptions of organizational justice and levels of organizational commitment. Moreover, focusing on non-family employees of family firms, the study assesses the relation between the perceptions of organizational justice and levels of organizational commitment. Finally, the study seeks to understand which dimension of organizational commitment (i.e. affective, continuance, ...
Tópico(s): Entrepreneurship Studies and Influences
2020 - Emerald Publishing Limited | International Journal of Organization Theory and Behavior
Catarina Brito, Taciana Raquel Bertotti, Maria João Primitivo, Marta Neves, Cristiana L. Pires, Pedro F. Cruz, Patrícia A. T. Martins, Ana Cristina Rodrigues, Maria João Moreno, Rui M. M. Brito, Maria Jorge Campos, Daniela C. Vaz, Maria Fernanda Pessoa, Fernando C. Lidon, Fernando H. Reboredo, Vânia Ribeiro,
Edible wild plants are part of the ethnobotanical and gastronomic heritage of different geographical areas. Corema album (L.) D. Don is an endemic species of the dune systems of the Atlantic coast of the Iberian Peninsula. The aerial parts of Corema album are a source of nutrients and antioxidants. The Corema album white berry (Portuguese crowberry) is rich in calcium, iron, and zinc. The plant also shows high phenolic content and antioxidant capacity associated with the leaves, fruit, and flowers. ...
Tópico(s): Botanical Research and Applications
2020 - Elsevier BV | Food Chemistry
Produção Nacional
Revisado por pares
Renata M. Pirani, Fernanda P. Werneck, Andréa T. Thomaz, Mariah L. Kenney, Marcelo José Sturaró, Teresa C. S. Ávila‐Pires, Pedro L. V. Peloso, Miguel Tréfaut Rodrigues, L. Lacey Knowles,
Abstract Aim Present Amazonian diversity patterns can result from many different mechanisms and, consequently, the factors contributing to divergence across regions and/or taxa may differ. Nevertheless, the river‐barrier hypothesis is still widely invoked as a causal process in divergence of Amazonian species. Here we use model‐based phylogeographic analyses to test the extent to which major Amazonian rivers act similarly as barriers across time and space in two broadly distributed Amazonian taxa. ...
Tópico(s): Identification and Quantification in Food
2019 - Wiley | Journal of Biogeography
Produção Nacional
Revisado por pares
Vincenzo Giordano, Hilton Augusto Koch, Alexandre Leme Godoy‐Santos, William Dias Belangero, Robinson Esteves Santos Pires, Pedro José Labronici,
Background: The advent of telemedicine has allowed physicians to deliver medical treatment to patients from a distance. Mobile apps such as WhatsApp Messenger, an instant messaging service, came as a novel concept in all fields of social life, including medicine. The use of instant messaging services has been shown to improve communication within medical teams by providing means for quick teleconsultation, information sharing, and starting treatment as soon as possible. Objective: The aim of this ...
Tópico(s): Telemedicine and Telehealth Implementation
2017 - JMIR Publications | Interactive Journal of Medical Research
Virgínia M. R. Pires, Pedro M. Pereira, Joana L. A. Brás, M.A.S. Correia, Vânia Cardoso, Pedro Bule, Victor D. Alves, Shabir Najmudin, I. Venditto, L.M.A. Ferreira, Maria João Romão, Ana Luı́sa Carvalho, C.M.G.A. Fontes, D.M.F. Prazeres,
Deconstruction of cellulose, the most abundant plant cell wall polysaccharide, requires the cooperative activity of a large repertoire of microbial enzymes. Modular cellulases contain non-catalytic type A carbohydrate-binding modules (CBMs) that specifically bind to the crystalline regions of cellulose, thus promoting enzyme efficacy through proximity and targeting effects. Although type A CBMs play a critical role in cellulose recycling, their mechanism of action remains poorly understood. Here ...
Tópico(s): Enzyme Production and Characterization
2017 - Elsevier BV | Journal of Biological Chemistry
Produção Nacional
Murilo José de Souza Pires, Pedro Ramos,
Tem por finalidade compreender o termo modernização conservadora e como este foi utilizado pelos analistas brasileiros. Utiliza os recursos técnicos da pesquisa bibliográfica e o método analítico descritivo. Os resultados encontrados demonstram, em linhas gerais, que o termo modernização conservadora foi elaborado por Barrington Moore Junior para retratar o caso específico de desenvolvimento capitalista na Alemanha e no Japão, os quais realizaram revoluções burguesas vindas de cima. Assim, o processo ...
Tópico(s): Brazilian History and Foreign Policy
2017 - Bank of the Northeast | Revista Econômica do Nordeste
Produção Nacional
Revisado por pares
Vincenzo Giordano, William Dias Belangero, Robinson Esteves Santos Pires, Pedro José Labronici,
Purpose: The purpose of this article is to explore the real-life practice of clinical management of humeral shaft fracture associated with traumatic radial nerve palsy among orthopedic trauma surgeons. Methods: Two hundred seventy-nine orthopedic surgeons worldwide reviewed 10 real cases of a humeral shaft fracture associated with traumatic radial nerve palsy answering two questions: (1) What treatment would you choose/recommend: nonoperative or operative? (2) What are the reasons for your decision- ...
Tópico(s): Elbow and Forearm Trauma Treatment
2017 - SAGE Publishing | Journal of orthopaedic surgery
Daniel Pires, Pedro Beja, María Filomena Magalhães,
ABSTRACT Movement may critically influence population persistence in the face of disturbance. However, data on individual movements into and out of refugia in response to disturbance remain limited, leading to an incomplete understanding of the ecological significance of mobility. Using individually marked chubs Squalius torgalensis in a seasonally drying Mediterranean stream, we quantified the rate, direction and magnitude of movements out of dry season pools, and of movements displayed across ...
Tópico(s): Aquatic Invertebrate Ecology and Behavior
2014 - Wiley | River Research and Applications
Produção Nacional
Revisado por pares
Daniele Araújo Pires, Pedro Elias Marques, Rafaela Vaz Sousa Pereira, Bruna Araújo David, Lindisley Ferreira Gomides, Ana Carolina Fialho Dias, Albená Nunes-Silva, Vanessa Pinho, Denise Carmona Cara, Leda Quércia Vieira, Mauro Martins Teixeira, Gustavo Batista Menezes,
Tópico(s): Liver Disease and Transplantation
2013 - Springer Science+Business Media | Inflammation Research
Alexandre M. Ramos, Ana Cordeiro Pires, Pedro M. Sousa, Ricardo M. Trigo,
Abstract Coastal upwelling is a phenomenon that occurs in most western oceanic coasts, associated with coastal surface water divergence and consequent ascension of colder and nutrient-rich waters from deeper levels. In this work, we evaluate the intra- and interannual variability of the upwelling index (UI) off the western coast of the Iberian Peninsula considering six locations at various latitudes along the 10°W meridian: Rias Baixas (42°N), Aveiro (41°N), Figueira da Foz (40°N), Cabo da Roca (39°N), ...
Tópico(s): Ocean Waves and Remote Sensing
2013 - Elsevier BV | Continental Shelf Research
Válter Martins, Rui Pires, Pedro Cabral,
Tópico(s): Land Use and Ecosystem Services
2012 - Springer Science+Business Media | Journal of Coastal Conservation
Mahaut de Vareilles, Nadège Richard, Paulo J. Gavaia, Tomé S. Silva, Odete Cordeiro, Inês Guerreiro, Manuel Yúfera, Irineu Batista, Carla Pires, Pedro Pousão‐Ferreira, Pedro M. Rodrigues, Ivar Rønnestad, Kari E. Fladmark, Luís E.C. Conceição,
In order to investigate the effects of dietary protein hydrolysates (PH) on larval growth performance, skeleton quality and proteome expression, triplicate groups of white seabream (Diplodus sargus) larvae were co-fed from first-feeding with live feed and three microencapsulated diets differing in the molecular weight of their PH fraction (Control – inclusion of CPSP-90; H – inclusion of a high amount in 0.5–30 kDa hydrolysates; L – inclusion of a high amount in <0.5 kDa hydrolysates). At 15 days after hatching ( ...
Tópico(s): Reproductive biology and impacts on aquatic species
2012 - Wiley | Journal of Applied Ichthyology
Produção Nacional
Revisado por pares
Priscila Oliveira de Souza, Lizângela R. Ferreira, Natanael R. X. Pires, Pedro José Sanches Filho, Fábio A. Duarte, Cláudio M. P. Pereira, Márcia F. Mesko,
Currently, algae and algae products are extensively applied in the pharmaceutical, cosmetic and food industries. Algae are the main organisms that take up and store heavy metals. Therefore, the use of compounds derived from algae by the pharmaceutical industry should be closely monitored for possible contamination. The pollution generated by heavy metals released by industrial and domestic sources causes serious changes in the aquatic ecosystem, resulting in a loss of biological diversity and a ...
Tópico(s): Algal biology and biofuel production
2012 - Springer Science+Business Media | Revista Brasileira de Farmacognosia