Paulo Navarro‐Costa, Luı́sa Pereira, Cı́ntia Alves, Leonor Gusmão, Carmen Proença, Pedro Marques‐Vidal, Tiago Rocha, Sónia Cristina Heleno Correia, Sónia Jorge, António J. R. Neves, Ana Paula Soares, Joaquim Nunes, Carlos Calhaz–Jorge, António Amorim, Carlos E. Plancha, João Gonçalves,
The AZFc region of the human Y chromosome is a highly recombinogenic locus containing multi-copy male fertility genes located in repeated DNA blocks (amplicons). These AZFc gene families exhibit slight sequence variations between copies which are considered to have functional relevance. Yet, partial AZFc deletions yield phenotypes ranging from normospermia to azoospermia, thwarting definite conclusions on their real impact on fertility.The amplicon content of partial AZFc deletion products was characterized ...
Tópico(s): Sperm and Testicular Function
2007 - BioMed Central | BMC Genomics
Joana C. Costa, Tiago Roxo, João B. F. Sequeiros, Hugo Proença, Pedro R. M. Inácio,
Cybercrime affects companies worldwide, costing millions of dollars annually. The constant increase of threats and vulnerabilities raises the need to handle vulnerabilities in a prioritized manner. This prioritization can be achieved through Common Vulnerability Scoring System (CVSS), typically used to assign a score to a vulnerability. However, there is a temporal mismatch between the vulnerability finding and score assignment, which motivates the development of approaches to aid in this aspect. ...
Tópico(s): Spam and Phishing Detection
2022 - Institute of Electrical and Electronics Engineers | IEEE Access
Ana P. Proença, Pedro Dinis Gaspar, Tânia M. Lima,
The organizations of horticultural producers and, particularly, those that deal with extremely perishable endogenous fruits, such as peaches and cherries, have a greater need to optimize production flows and processes. A particularity of the horticultural industry is the short shelf life of raw materials and the seasonality of products. In this paper, optimization techniques are used to improve the production flows and the management of cold storage and distribution in a fruit central. The application ...
Tópico(s): Sustainable Supply Chain Management
2022 - Multidisciplinary Digital Publishing Institute | Processes
Elias Soukiazis, Sara Proença, Pedro André Cerqueira,
Although the relationship between renewable energy and economic performance has attracted the interest of researchers in recent years, most of the analysis has focused on economic growth, which does not reflect the quality of standards of living. We employ a different approach measuring the impact of renewable energy consumption on the Human Development Index, which also considers qualitative characteristics. Using a simultaneous equation system approach that describes the interrelations between ...
Tópico(s): Energy, Environment, and Transportation Policies
2019 - SAGE Publishing | The Energy Journal
Inês Araújo, Filipa Marquês, Sandra André, Manuel Araújo, Sara Marques, Rita Ferreira, Patrícia Moniz, Margarida Proença, Pedro Borrego, Cândida Fonseca,
Tópico(s): Asthma and respiratory diseases
2018 - Springer Science+Business Media | Sleep And Breathing
Eduardo Assunção, Pedro Dinis Gaspar, Ricardo Mesquita, Maria Paula Simões, António Ramos, Hugo Proença, Pedro R. M. Inácio,
Fruit detection is crucial for yield estimation and fruit picking system performance. Many state-of-the-art methods for fruit detection use convolutional neural networks (CNNs). This paper presents the results for peach detection by applying a faster R-CNN framework in images captured from an outdoor orchard. Although this method has been used in other studies to detect fruits, there is no research on peaches. Since the fruit colors, sizes, shapes, tree branches, fruit bunches, and distributions ...
Tópico(s): Leaf Properties and Growth Measurement
2022 - Multidisciplinary Digital Publishing Institute | Climate
Tiago Vaquero, Guglielmo Daddi, Rohan Thakker, Michael Paton, Ashkan Jasour, Marlin P. Strub, R. Michael Swan, Rob Royce, Matthew Gildner, Phillipe Tosi, Marcel Veismann, P. Gavrilov, Eloïse Marteau, Joseph Bowkett, Daniel Loret de Mola Lemus, Yashwanth Kumar Nakka, Benjamin Hockman, Andrew L. Orekhov, Tristan Hasseler, Carl Leake, Benjamin Nuernberger, Pedro F. Proença, William J. Reid, William Henry Fox Talbot, N. Georgiev, Torkom Pailevanian, Avak Archanian, Eric Ambrose, Jay Jasper, Robert Ian Etheredge, Charles T. Roman, Dan Levine, Kyohei Otsu, Sarah Yearicks, Hovhannes Melikyan, Richard Rieber, Kalind Carpenter, Jeremy Nash, Abhinandan Jain, Lori Shiraishi, M. Robinson, Matthew Travers, Howie Choset, Joel W. Burdick, Alex Gardner, Morgan L. Cable, Michel D. Ingham, Masahiro Ono,
Ice worlds are at the forefront of astrobiological interest because of the evidence of subsurface oceans. Enceladus in particular is unique among the icy moons because there are known vent systems that are likely connected to a subsurface ocean, through which the ocean water is ejected to space. An existing study has shown that sending small robots into the vents and directly sampling the ocean water is likely possible. To enable such a mission, NASA’s Jet Propulsion Laboratory is developing a snake- ...
Tópico(s): Planetary Science and Exploration
2024 - American Association for the Advancement of Science | Science Robotics
Sofia Modesto Saramago, Joana Catarina Cominho, Sara Soares Marques Proença, Pedro João Casado Conde, Filomena Nunes,
Abstract Asymptomatic female genital tract colonization with Actinomyces spp is not uncommon, particularly among intrauterine device users. Pelvic actinomycosis is an extremely rare disease. The clinical picture can resemble an advanced ovarian malignancy. We report a case of pelvic actinomycosis mimicking ovarian malignancy diagnosed postoperatively. Preoperative diagnosis is possible if there is a high index of suspicion, obviating extensive surgery and preserving fertility, since long term antibiotic ...
Tópico(s): Bladder and Urothelial Cancer Treatments
2019 - Thieme Medical Publishers (Germany) | Revista Brasileira Ginecologia e Obstetrícia
Produção Nacional
Revisado por pares
Lívia Bitencourt Pascoal, Patrícia Brito Rodrigues, Lívia Moreira Genaro, Arilson Bernardo dos Santos Pereira Gomes, Daniel A. Toledo-Teixeira, Pierina Lorencini Parise, Karina Bispo-dos-Santos, Camila L. Simeoni, Paula Veri Guimarães, Lucas I Buscaratti, João Gabriel de Angeli Elston, Henrique Marques‐Souza, Daniel Martins‐de‐Souza, Maria de Lourdes Setsuko Ayrizono, Lı́cio A. Velloso, José Luiz Proença-Módena, Pedro M. Moraes‐Vieira, Marcelo A. Mori, Alessandro Farias, Marco Aurélio Ramirez Vinolo, Raquel Franco Leal,
Microbiota-derived molecules called short-chain fatty acids (SCFAs) play a key role in the maintenance of the intestinal barrier and regulation of immune response during infectious conditions. Recent reports indicate that SARS-CoV-2 infection changes microbiota and SCFAs production. However, the relevance of this effect is unknown. In this study, we used human intestinal biopsies and intestinal epithelial cells to investigate the impact of SCFAs in the infection by SARS-CoV-2. SCFAs did not change ...
Tópico(s): Long-Term Effects of COVID-19
2021 - Landes Bioscience | Gut Microbes
Produção Nacional
Revisado por pares
Juliana Coatrini Soares, Andrey Coatrini Soares, Monara Kaelle S.C. Angelim, José Luiz Proença-Módena, Pedro M. Moraes‐Vieira, L. H. C. Mattoso, Osvaldo N. Oliveira,
Mass testing for the diagnostics of COVID-19 has been hampered in many countries owing to the high cost of the methodologies to detect genetic material of SARS-CoV-2. In this paper, we report on a low-cost immunosensor capable of detecting the spike protein of SARS-CoV-2, including in samples of inactivated virus. Detection is performed with electrical impedance spectroscopy using an immunosensor that contains a monolayer film of carboxymethyl chitosan as matrix, coated with an active layer of antibodies ...
Tópico(s): Advanced biosensing and bioanalysis techniques
2021 - Elsevier BV | Talanta
... Carlos Neto de Carvalho, Andrea Baucon, Davide Badano, Pedro Proença Cunha, Cristiana Ferreira, Silvério Figueiredo, Fernando Muñiz, João ...
Tópico(s): Archaeology and ancient environmental studies
1994 - University of Chicago Press | Current Anthropology
Filipa Alves da Costa, Inês Teixeira, Filipa Duarte‐Ramos, Luís Proença, Ana Rita Pedro, Cristina Furtado, José Aranda da Silva, José Cabrita,
Background In view of the current financial and demographic situation in Portugal, accessibility to health care may be affected, including the ability to adhere to medication. Objective To evaluate the perceived effects of the crisis on elderly patient's access to medicines and medical care, and its implications on medicine-taking behaviour. Setting Community pharmacy. Method A cross-sectional study was undertaken during April 2013, where elderly patients answered a self-administered questionnaire ...
Tópico(s): Healthcare Systems and Reforms
2016 - Springer Science+Business Media | International Journal of Clinical Pharmacy
David Ferreira Lopes Santos, Miguel A. Machado, J. Monteiro, José Pedro Sousa, C. Sofia Proença, Fernando Crivellaro, Luís S. Rosado, Telmo G. Santos,
This paper presents an automated Non-Destructive Testing (NDT) system for the in-service inspection of orbital welds on tubular components operating at temperatures as high as 200 °C. The combination of two different NDT methods and respective inspection systems is here proposed to cover the detection of all potential defective weld conditions. The proposed NDT system combines ultrasounds and Eddy current techniques with dedicated approaches for dealing with high temperature conditions. Phased array ...
Tópico(s): Thermography and Photoacoustic Techniques
2023 - Multidisciplinary Digital Publishing Institute | Sensors
This work proposes a robust visual odometry method for structured environments that combines point features with line and plane segments, extracted through an RGB-D camera. Noisy depth maps are processed by a probabilistic depth fusion framework based on Mixtures of Gaussians to denoise and derive the depth uncertainty, which is then propagated throughout the visual odometry pipeline. Probabilistic 3D plane and line fitting solutions are used to model the uncertainties of the feature parameters ...
Tópico(s): Image and Object Detection Techniques
2018 - Elsevier BV | Robotics and Autonomous Systems
João Proença, Cláudia Quaresma, Pedro Vieira,
The aim of this research is to carry out a systematic review of the use of technological gaming platforms with serious games in the upper limb rehabilitation of patients with neuromotor disorders. Through a systematic review, the first two authors defined the inclusion criteria and extracted the data, resulting in 38 studies collected from B-On, PubMed and Medline. Ninety-two per cent of the selected articles were published since 2010. This review documents 35 different gaming platforms types. Twenty- ...
Tópico(s): Botulinum Toxin and Related Neurological Disorders
2017 - Taylor & Francis | Disability and Rehabilitation Assistive Technology
Pedro F. Proença, Raul Laureano, Luís Laureano,
This study aims to investigate the determinants of Portuguese SMEs capital structure and to examine the effects of the 2008 financial crisis on Portuguese SMEs capital structure. The sample used considers the period 2007-2010, resulting in 12,857 Portuguese SMEs. Results suggest that liquidity, asset structure and profitability are the most important determinants explaining the capital structure of Portuguese SMEs. We report a downward tendency on companies' debt ratios levels during the financial ...
Tópico(s): Working Capital and Financial Performance
2014 - Elsevier BV | Procedia - Social and Behavioral Sciences
David Emanuel Gomes, Maria Inês D. Iglésias, Ana P. Proença, Tânia M. Lima, Pedro Dinis Gaspar,
Route optimization has become an increasing problem in the transportation and logistics sector within the development of smart cities. This article aims to demonstrate the implementation of a genetic algorithm adapted to a Vehicle Route Problem (VRP) in a company based in the city of Covilhã (Portugal). Basing the entire approach to this problem on the characteristic assumptions of the Multiple Traveling Salesman Problem (m-TSP) approach, an optimization of the daily routes for the workers assigned ...
Tópico(s): Urban and Freight Transport Logistics
2021 - Multidisciplinary Digital Publishing Institute | Electronics
Margaret M. Hannan, H. Peres, Fernando Maltêz, Andrew Hayward, João Machado, A Morgado, Rui Proença, M Nelson, João Pedro Bernardo Vieira Martins Bico, D B Young, Brian Gazzard,
An increase in the number of new cases of tuberculosis (TB) combined with poor clinical outcome was identified among HIV-infected injecting drug users attending a large HIV unit in central Lisbon. A retrospective epidemiological and laboratory study was conducted to review all newly diagnosed cases of TB from 1995 to 1996 in the HIV unit. Results showed that from 1995 to 1996, 63% (109/173) of the Mycobacterium tuberculosis isolates from HIV-infected patients were resistant to one or more anti-tuberculosis ...
Tópico(s): Infectious Diseases and Tuberculosis
2001 - Elsevier BV | Journal of Hospital Infection
Produção Nacional
Revisado por pares
Natália S. Brunetti, Gustavo Gastão Davanzo, Diogo de Moraes, A. Ferrari, Gabriela Fabiano de Souza, Stéfanie Primon Muraro, Thiago L. Knittel, Vinícius O. Boldrini, Lauar de Brito Monteiro, João Victor Virgílio-da-Silva, Gerson S. Profeta, Natália Sayuri Wassano, Luana Nunes Santos, Victor Corasolla Carregari, Artur HS Dias, Flávio P. Veras, Lucas Tavares, Julia Forato, Ícaro Maia Santos de Castro, Lícia C. Silva-Costa, André C. Palma, Eli Mansour, Raisa G. Ulaf, Ana Flávia Bernardes, Thyago A. Nunes, Luciana C. Ribeiro, Marcus V. Agrela, Maria Luíza Moretti, Lucas I Buscaratti, Fernanda Crunfli, Raissa G. Ludwig, Jaqueline Aline Gerhardt, Natália Munhoz-Alves, Ana Maria Marques, Renata Sesti‐Costa, Mariene R. Amorim, Daniel A. Toledo-Teixeira, Pierina Lorencini Parise, Matheus Cavalheiro Martini, Karina Bispos-dos-Santos, Camila L. Simeoni, Fabiana Granja, Virgínia Campos Silvestrini, Eduardo Basílio de Oliveira, Vítor M. Faça, Murilo de Carvalho, Bianca Gazieri Castelucci, Alexandre Borin, Laís D. Coimbra, Marieli M. G. Dias, Patrícia Brito Rodrigues, Arilson Bernardo SP Gomes, Fabrício Bíscaro Pereira, Leonilda MB Santos, Louis-Marie Bloyet, Spencer Stumpf, Marjorie Cornejo Pontelli, Sean P. J. Whelan, Andrei C. Spósito, Robson Francisco Carvalho, André Schwambach Vieira, Marco AR Vinolo, André Damásio, Lı́cio A. Velloso, Ana Carolina Migliorini Figueira, Luis LP da Silva, Thiago M. Cunha, Helder I. Nakaya, Henrique Marques‐Souza, Rafael Elias Marques, Daniel Martins‐de‐Souza, Munir S. Skaf, José Luiz Proença-Módena, Pedro M. Moraes‐Vieira, Marcelo A. Mori, Alessandro S. Farias,
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the agent of a major global outbreak of respiratory tract disease known as Coronavirus Disease 2019 (COVID-19). SARS-CoV-2 infects mainly lungs and may cause several immune-related complications, such as lymphocytopenia and cytokine storm, which are associated with the severity of the disease and predict mortality. The mechanism by which SARS-CoV-2 infection may result in immune system dysfunction is still not fully understood. Here, ...
Tópico(s): Long-Term Effects of COVID-19
2023 - eLife Sciences Publications Ltd | eLife
Joana C. Costa, Tiago Roxo, Hugo Proença, Pedro R. M. Inácio,
Deep Learning is currently used to perform multiple tasks, such as object recognition, face recognition, and natural language processing. However, Deep Neural Networks (DNNs) are vulnerable to perturbations that alter the network prediction, named adversarial examples, which raise concerns regarding the usage of DNNs in critical areas, such as Self-driving Vehicles, Malware Detection, and Healthcare. This paper compiles the most recent adversarial attacks in Object Recognition, grouped by the attacker ...
Tópico(s): Advanced Malware Detection Techniques
2024 - Institute of Electrical and Electronics Engineers | IEEE Access
Produção Nacional
Revisado por pares
Mieke Metzemaekers, Seppe Cambier, Marfa Blanter, Jennifer Vandooren, Ana Carolina de Carvalho, Bert Malengier‐Devlies, Lore Vanderbeke, Cato Jacobs, Sofie Coenen, Erik Martens, Noëmie Pörtner, Lotte Vanbrabant, Pierre Van Mol, Yannick Van Herck, Nathalie Van Aerde, Greet Hermans, Jan Gunst, Alexandre Borin, Bruna Toledo Nunes Pereira, Arilson Bernardo dos Santos Pereira Gomes, Stéfanie Primon Muraro, Gabriela Fabiano de Souza, Alessandro S. Farias, José Luiz Proença-Módena, Marco Aurélio Ramirez Vinolo, Pedro Elias Marques, Carine Wouters, Els Wauters, Sofie Struyf, Patrick Matthys, Ghislain Opdenakker, Rafael Elias Marques, Joost Wauters, Mieke Gouwy, Paul Proost,
Abstract Objectives Emerging evidence of dysregulation of the myeloid cell compartment urges investigations on neutrophil characteristics in coronavirus disease 2019 (COVID‐19). We isolated neutrophils from the blood of COVID‐19 patients receiving general ward care and from patients hospitalised at intensive care units (ICUs) to explore the kinetics of circulating neutrophils and factors important for neutrophil migration and activation. Methods Multicolour flow cytometry was exploited for the analysis ...
Tópico(s): Sepsis Diagnosis and Treatment
2021 - Wiley | Clinical & Translational Immunology
Mariana P. Proença, Miguel Mota Prego Rosmaninho, Pedro M. Resende, C. T. Sousa, J. Ventura, J. P. Araújo, Lisete Fernandes, Pedro B. Tavares, André M. Pereira,
Bi2Te3 is the most commonly used thermoelectric material in modern solid-state refrigerators and power generators based on this basic principle. Due to predictions of significant improvements in their efficiency by using nanostructured materials, a thorough study on thin films and nanowires deposited by the electrodeposition method are here presented. The study of the deposition applied potential effect on the morphology, stoichiometry and crystallinity of both thin films and nanowires has been ...
Tópico(s): nanoparticles nucleation surface interactions
2017 - Elsevier BV | Materials & Design
Sónia C. Correia, Cristina Carvalho, Maria S. Santos, Teresa Proença, Elsa Nunes, Ana I. Duarte, Pedro Monteiro, Raquel Seiça, Catarina R. Oliveira, Paula I. Moreira,
We aimed to investigate whether metformin protects the brain against the oxidative imbalance promoted by type 2 diabetes. This study analyzed the effect of metformin on oxidative stress markers (thiobarbituric acid reactive substances (TBARS), malondialdehyde (MDA) and carbonyl groups), hydrogen peroxide (H2O2) levels, non-enzymatic antioxidant defenses [reduced (GSH) and oxidized (GSSG) glutathione and vitamin E] and enzymatic antioxidant defenses [glutathione peroxidase (GPx), glutathione reductase (GRed) ...
Tópico(s): Metabolism, Diabetes, and Cancer
2008 - Bentham Science Publishers | Medicinal Chemistry
Ricardo Proença, Arminda Lopes, Pedro Campos,
The authors present a new system that exploits novel human-machine interfaces based on the recognition of static gestures of human hands. The aim is to aid the occupant of a wheelchair to have access to certain objects in order to facilitate his or her daily life. The authors’ approach is based on simple computational processes and low-cost hardware. Its development involves a comprehensive approach to computer vision problems based on video image capture, image segmentation, feature extraction, ...
Tópico(s): Human Pose and Action Recognition
2013 - IGI Global | International Journal of Sociotechnology and Knowledge Development
Produção Nacional
Revisado por pares
Carolyn Elinore Barnes Proença, Lúcia Helena Soares-Silva, Pedro Ítalo Tanno Silva, Suzane Margaret Fank-de-Carvalho,
Tópico(s): Fern and Epiphyte Biology
2010 - Springer Science+Business Media | Kew Bulletin
Produção Nacional
Revisado por pares
Matheus Cândido Hemerly, Diogo Turiani Hourneaux de Moura, Epifânio Silvino do Monte, Ígor Mendonça Proença, Igor Braga Ribeiro, Erika Yuki Yvamoto, Pedro Henrique Boraschi Vieira Ribas, Sergio A. Sánchez‐Luna, Wanderley Marques Bernardo, Eduardo Guimarães Hourneaux de Moura,
Tópico(s): Pancreatic and Hepatic Oncology Research
2022 - Springer Science+Business Media | Surgical Endoscopy
Mariana P. Proença, C. T. Sousa, André M. Pereira, Pedro B. Tavares, J. Ventura, M. Vázquez, J. P. Araújo,
NiO nanoparticles (NPs) were prepared by a sol–gel process using the citrate route. The sol–gel parameters were tuned to obtain samples with different average particle sizes, ranging from 12 to 70 nm. Magnetic characterization revealed an increase in the blocking temperature with the diameter of the NPs and an increase in the effective magnetic anisotropy (Keff) with decreasing particle size. The magnetic moment per particle was calculated for all samples using the susceptibility value at T = 300 K. ...
Tópico(s): ZnO doping and properties
2011 - Royal Society of Chemistry | Physical Chemistry Chemical Physics
This work proposes a visual odometry method that combines points and plane primitives, extracted from a noisy depth camera. Depth measurement uncertainty is modelled and propagated through the extraction of geometric primitives to the frame-to-frame motion estimation, where pose is optimized by weighting the residuals of 3D point and planes matches, according to their uncertainties. Results on an RGB-D dataset show that the combination of points and planes, through the proposed method, is able to ...
Tópico(s): 3D Surveying and Cultural Heritage
2017 - Springer Science+Business Media | Lecture notes in computer science
Pedro António Janeiro, Isabel Proença, Vítor da Conceição Gonçalves,
The service innovation literature lacks empirical studies that focus on the links between service firms and universities. This paper aims to contribute to a better understanding of these links. This paper applies the Portuguese version of the Community Innovation Survey (CIS 2006) to obtain data on 967 service firms. The model uses a random intercept in an ordered probit regression to empirically assess which factors influence the collaboration of service firms with universities for innovation related ...
Tópico(s): Service and Product Innovation
2013 - Elsevier BV | Journal of Business Research
Produção Nacional
Marília M. Guimarães, Carla T.G. Guerra, Solange Travassos de Figueiredo Alves, Maria C.S.A. Cunha, Luiz A. Marins, Luiz Felipe Mena Barreto, Evelyn Teich, Flávia Nardes, José F.R. Ornellas, Gerson Carakushansky, Gustavo Pinheiro, Helena P. Oliveira, Isabel C.R. Beserra, Juraci Ghiaroni, Marcelo V. Peixoto, Maria Lúcia Fleiuss Farias, Mônica M.A. Lanfredi, Munira Aiex Proença, Paula P. Ramalho, Pedro de Sena Murteira Pinheiro, Roberto Zagury, Roberto Azevedo Antunes,
Neste trabalho descrevemos as malformações e co-morbidades observadas em pacientes com síndrome de Turner (ST). Foi realizado um estudo retrospectivo, avaliando os prontuários de 60 pacientes cujo diagnóstico de ST foi confirmado através do cariótipo, desde a fase pré-natal até a idade de 49 anos. As pacientes encontram-se com idades entre 1 e 50 anos e foram evoluídas num período de 4 meses a 29 anos. Trinta e uma apresentavam o cariótipo 45XO, 24 eram mosaico e 5 apresentavam o padrão 46Xi, (i,Xq). ...
Tópico(s): Genomic variations and chromosomal abnormalities
2001 - Editora da Universidade de São Paulo | Arquivos Brasileiros de Endocrinologia & Metabologia