G. Kober, S Pennaforte, Tahisha M. Buck, H. Sievert, C. Vallbracht,
... author on: Oxford Academic PubMed Google Scholar S. Pennaforte, S. Pennaforte Clinic NordrheinErnst-Ludwig-Ring 2, D 6350 Bad ...
Tópico(s): Acute Myocardial Infarction Research
1993 - Oxford University Press | European Heart Journal
... top Next FiguresReferencesRelatedDetailsCited By Detry J, Sellier P, Pennaforte S, Cokkinos D, Dargie H and Mathes P ( ...
Tópico(s): Statistical Methods in Clinical Trials
1979 - Lippincott Williams & Wilkins | Circulation
... date: 1-Aug-1995. Detry J, Sellier P, Pennaforte S, Cokkinos D, Dargie H and Mathes P ( ...
Tópico(s): Coronary Interventions and Diagnostics
1990 - Lippincott Williams & Wilkins | Circulation
Patrick J. Willems, John M. Opitz,
... 481–485. Fandre M, Leroux B, Coucrur N, Pennaforte F, Pluot B (1972): Hydrocéphalie liée au sexe. ...
Tópico(s): Fetal and Pediatric Neurological Disorders
1988 - Wiley | American Journal of Medical Genetics
Teddy Grand, David Mordasini, Sébastien L’Hoste, Thomas Pennaforte, Mathieu Genête, Marie-Jeanne Biyeyeme, Rosa Vargas‐Poussou, Anne Blanchard, Jacques Teulon, Stéphane Lourdel,
Tópico(s): Ion Transport and Channel Regulation
2009 - Elsevier BV | Kidney International
J. Cohen, H. Lutz, J.-L. Pennaforte, Audrey Bouchard, M Kazatchkine,
SUMMARY The present study investigated the rate of catabolism of CR1 (the C3b receptor, CD35) on erythrocytes (E) in vivo, in relationship with the expressed number of CR1/E, the CR1.1. Hin dIII quantitative CR1 polymorphism, and cell age. The relationship between the number of CR1/E and cell age was analysed by measuring G6PDH activity in E that had been sorted according to high or low expression of CR1 (CD35), by assessing the expression of CR1 (CD35)on E separated according to cell density, and by ...
Tópico(s): T-cell and B-cell Immunology
1992 - Oxford University Press | Clinical & Experimental Immunology
Pascale Cornillet, Philippe Gredy, J.L. Pennaforte, Olivier Meyer, M Kazatchkine, J. Cohen,
SUMMARY The allotypic forms of the C3b/C4b receptor (CR1, CD35) differ in length, in the number of expressed C3b binding sites and thus in their ability to mediate the processing of circulating C3- and C4-bearing immune complexes. We have used a combination of three informative restriction fragment length polymorphisms (RFLPs) to assess the frequencies of the F (most frequent allele comprised of four long homologous repeats (LHR)), S (five LHR) and F′ (three LHR) alleles of the C3b/C4b receptor (CR1, CD35) ...
Tópico(s): Chronic Lymphocytic Leukemia Research
1992 - Oxford University Press | Clinical & Experimental Immunology
Claudio Pascale, Paolo Fornengo, Giuseppe Epifani, Albino Claudio Bosio, F Giacometto,
... radical cell-membrane damage,3Detry JM Sellier P Pennaforte S Cokkinos D Dargie H Mathes P Trimetazidine: ...
Tópico(s): Metal complexes synthesis and properties
2002 - Elsevier BV | The Lancet
Jm. Detry, Philippe Sellier, S Pennaforte, D COKKINOS, H J Dargie, P. Mathes,
1. Trimetazidine has a direct anti‐ischaemic effect on the myocardium without altering the rate x pressure product or coronary blood flow. 2. The effects of trimetazidine (20 mg three times daily) were compared with those of propranolol (40 mg three times daily) in a double‐blind parallel group multicentre study in 149 men with stable angina. 3. Reproducibility of exercise performance was verified during a 3 week run‐in placebo washout period. All patients had > 1 mm ST‐depression on exercise test. ...
Tópico(s): Cardiac electrophysiology and arrhythmias
1994 - Wiley | British Journal of Clinical Pharmacology
Damien Metz, Damien Jolly, Joelle Graciet-Richard, Pierre Nazeyrollas, Jean-Pierre Chabert, B Maillier, Jean‐Loup Pennaforte, J Elaerts,
Antiphospholipid antibodies in patients with sytemic lupus erythematosus (SLE) are often associated with thrombosis, recurrent abortions and thrombocytopenia. The purpose of this study was to evaluate the prevalence of cardiac valvular abnormalities in patients with SLE and to establish the relationship between the echographic findings and the presence of an antiphospholipid syndrome. A total of 52 consecutive patients with SLE and 52 healthy sex- and age-matched controls were therefore evaluated ...
Tópico(s): Platelet Disorders and Treatments
1994 - Karger Publishers | Cardiology
Olivier Rascol, Jean‐Philippe Azulay, Olivier Blin, Muriel Bonnet, Christine Brefel‐Courbon, Pierre Césaro, Philippe Damier, Bérengère Debilly, F. Durif, Monique Galitzky, Jean‐Marie Grouin, S Pennaforte, Gabriel Villafane, Sadek Yaici, Y. Agid,
S90049, a novel sublingual formulation of the non-ergoline D(2)-D(3) agonist piribedil, has a pharmacokinetic profile promising to provide rapid relief on motor signs in Parkinson's disease (PD). We assessed the efficacy and safety of S90049 in aborting OFF episodes responding to subcutaneous apomorphine in PD patients with motor fluctuations. This was a single-dose double-blind double-placebo 3 x 3 cross-over study. Optimal tested doses were determined during a previous open-label titration phase ( ...
Tópico(s): Neurological disorders and treatments
2010 - Wiley | Movement Disorders
Thomas Pennaforte, S Klosowski, C. Alexandre, J. Ghesquiêre, Thameur Rakza, Laurent Storme,
Évaluer de façon prospective l’intérêt du refoulement manuel du foie pendant la pose d’un cathéter veineux ombilical (CVO) sur la réduction du taux d’échec de positionnement « central » (jonction veine cave inférieure–oreillette droite) de l’extrémité du CVO. Soixante-cinq nouveau-nés admis dans 3 unités de soins intensifs néonatals sur une période de 4 mois ont été inclus. Si la position « sous-hépatique » du CVO était confirmée à la radiographie, le cathéter était retiré jusqu’au repère 3 cm. Une nouvelle ...
Tópico(s): Blood Coagulation and Thrombosis Mechanisms
2010 - Elsevier BV | Archives de Pédiatrie
Alexandra Heurgué, Fabien Vitry, Marie-Danièle Diébold, Nahla Yaziji, Brigitte Bernard‐Chabert, Jean‐Loup Pennaforte, R Picot, Hervé Louvet, Luc Frémond, Pierre A. Geoffroy, Jean‐Luc Schmit, Guillaume Cadiot, Gérard Thiéfin,
The aim of this retrospective study was to compare clinical, biological, and histological features and treatment response in 115 patients with overlap syndrome (OS), autoimmune hepatitis (AIH) or primary biliary cirrhosis (PBC).Consecutive patients with AIH, PBC or OS followed between 1984 and 2005 in five different centers were included. All data were re-evaluated using current diagnostic criteria of each disease.Fifteen patients had OS (13 females), 48 AIH (40 females) and 52 PBC (49 females). Patients ...
Tópico(s): Pancreatitis Pathology and Treatment
2007 - Elsevier BV | Gastroentérologie Clinique et Biologique
Teddy Grand, Sébastien L’Hoste, David Mordasini, Nadia Defontaine, Mathilde Keck, Thomas Pennaforte, Mathieu Genête, Kamel Laghmani, Jacques Teulon, Stéphane Lourdel,
Mutations in the electrogenic Cl(-)/H(+) exchanger ClC-5 gene CLCN5 are frequently associated with Dent disease, an X-linked recessive disorder affecting the proximal tubules. Here, we investigate the consequences in Xenopus laevis oocytes and in HEK293 cells of nine previously reported, pathogenic, missense mutations of ClC-5, most of them which are located in regions forming the subunit interface. Two mutants trafficked normally to the cell surface and to early endosomes, and displayed complex ...
Tópico(s): Ion Transport and Channel Regulation
2011 - Wiley | Human Mutation
Sophie Ng Wing Tin, N. Martin–Duverneuil, Ahmed Idbaïh, Cathérine Garel, Maria José Ribeiro, Judith Landman Parker, Anne Sophie Defachelles, Anne Lambilliotte, Mohamed Barkaoui, Martine Münzer, Martine Gardembas, Jean Sibilia, Patrick Lutz, R Fior, Michel Polak, Alain Robert, O. Aumaître, Dominique Plantaz, Corinne Armari‐Alla, T Généreau, P Bérard, Ghislain Nokam Talom, Jean‐Loup Pennaforte, Hubert Ducou Le Pointe, Marie-Anne Barthez, Gérard Couillault, Julien Haroche, Karima Mokhtari, Jean Donadieu, Khê Hoang‐Xuan,
Abstract Background Vinblastine (VBL) is the standard treatment for systemic Langerhans cell histiocytosis (LCH), but little is known about its efficacy in central nervous system (CNS) mass lesions. Methods A retrospective chart review was conducted. Twenty patients from the French LCH Study Group register met the inclusion criteria. In brief, they had CNS mass lesions, had been treated with VBL, and were evaluable for radiologic response. Results The median age at diagnosis of LCH was 11.5 years (range: ...
Tópico(s): Vascular Malformations and Hemangiomas
2011 - BioMed Central | Orphanet Journal of Rare Diseases
Mikaël Ebbo, Laurent Daniel, Michel Pavic, P. Sève, M. Hamidou, Emmanuel Andrès, Stéphane Burtey, L. Chiche, Jacques Serratrice, M. Longy‐Boursier, M. Ruivard, Julien Haroche, Bertrand Godeau, Anne-Bérengère Beucher, Jean‐Marie Berthelot, T. Papo, Jean‐Loup Pennaforte, A. Benyamine, N. Jourde, C. Landron, P. Roblot, Olivier Moranne, Christine Silvain, B. Granel, F. Bernard, V. Veit, K. Mazodier, E. Bernit, H Rousset, José Boucraut, Jean‐Jacques Boffa, Pierre‐Jean Weiller, Gilles Kaplanski, Pièrre Aucouturier, Jean‐Robert Harlé, N. Schleinitz,
IgG4-related systemic disease is now recognized as a systemic disease that may affect various organs. The diagnosis is usually made in patients who present with elevated IgG4 in serum and tissue infiltration of diseased organs by numerous IgG4+ plasma cells, in the absence of validated diagnosis criteria. We report the clinical, laboratory, and histologic characteristics of 25 patients from a French nationwide cohort. We also report the treatment outcome and show that despite the efficacy of corticosteroids, ...
Tópico(s): Gastrointestinal disorders and treatments
2011 - Wolters Kluwer | Medicine
Jodi I. Pike, Mary T. Donofrio, Charles I. Berul,
... Ninet J, Pangaud N, Papo T, Pellegrin J, Pennaforte J, Pouchot J, Sarrot-Reynauld F, Schleinitz N, ...
Tópico(s): Platelet Disorders and Treatments
2011 - Lippincott Williams & Wilkins | Circulation
Hervé Devilliers, Zahir Amoura, J.-F. Besancenot, Bernard Bonnotte, Jean‐Louis Pasquali, Denis Wahl, F. Maurier, P. Kaminsky, Jean‐Loup Pennaforte, N. Magy‐Bertrand, Laurent Arnaud, Christine Binquet, Françis Guillemin,
Objective. To cross-culturally adapt the LupusQoL into French, to test its measurement properties and to further investigate its domain structure. Methods. The cultural adaptation process according to guidelines and pre-testing resulted in the LupusQoL-FR. SLE patients completed the LupusQoL-FR at baseline, 15 days, 3 months and 6 months. Validity was studied through content and construct validity (factorial and Rasch analysis for structural validity, Spearman's correlation and Mann–Whitney tests ...
Tópico(s): Systemic Sclerosis and Related Diseases
2012 - Oxford University Press | Lara D. Veeken
Julie De Buyst, Thameur Rakza, Thomas Pennaforte, Anne-Britt Johansson, Laurent Storme,
Tópico(s): Mechanical Circulatory Support Devices
2012 - Elsevier BV | The Journal of Pediatrics
Produção Nacional
Revisado por pares
Carmen Penido, Karina A. Costa, R. J. Pennaforte, Maria Fernanda de Souza Costa, J. F. G. Pereira, Antônio Carlos Siani, Maria das Graças Henriques,
Tópico(s): Protein Hydrolysis and Bioactive Peptides
2005 - Springer Science+Business Media | Inflammation Research
J. Léone, Jean‐Pierre Vilque, B. Pignon, C. Marcus, Jean‐Loup Pennaforte, Jean‐Paul Eschard, J Etienne,
Tópico(s): Orthopaedic implants and arthroplasty
1996 - Springer Science+Business Media | Skeletal Radiology
... 123–130.CrossrefMedlineGoogle Scholar19 Detry JM, Sellier P, Pennaforte S, et al. Trimetazidine: a new concept in ...
Tópico(s): Adipose Tissue and Metabolism
2004 - Lippincott Williams & Wilkins | Circulation
... 1775–1778.MedlineGoogle Scholar9 Detry JM, Sellier P, Pennaforte S, Cokkinos D, Dargie H, Mathes P. Trimetazidine: ...
Tópico(s): Mitochondrial Function and Pathology
2000 - Lippincott Williams & Wilkins | Circulation Research
Hervé Devilliers, Z. Amoura, J.-F. Besancenot, Bernard Bonnotte, J.‐L. Pasquali, Denis Wahl, F. Maurier, P. Kaminsky, J.-L. Pennaforte, N. Magy‐Bertrand, Laurent Arnaud, Christine Binquet, F. Guillemin, Claire Bonithon‐Kopp,
This study aimed to estimate the responsiveness to change of a generic [the 36-item Short Form Health Survey (SF-36)] and a specific health-related quality of life questionnaire [the Lupus Quality if Life questionnaire (LupusQoL)] according to SLE patients' self-reported changes in health status.In a cohort of 185 SLE patients, quality of life (QoL) was measured three times at 3 month intervals by the LupusQoL and SF-36 questionnaires. Anchors for responsiveness were defined by patients' global assessment ...
Tópico(s): Atherosclerosis and Cardiovascular Diseases
2014 - Oxford University Press | Lara D. Veeken
Laurent Storme, E. Aubry, Thameur Rakza, Ali Houeijeh, V. Debarge, Pierre Tourneux, Philippe Deruelle, Thomas Pennaforte,
The main cause of pulmonary hypertension in newborn babies results from the failure of the pulmonary circulation to dilate at birth, termed ‘persistent pulmonary hypertension of the newborn’ (PPHN). This syndrome is characterized by sustained elevation of pulmonary vascular resistance, causing extrapulmonary right-to-left shunting of blood across the ductus arteriosus and foramen ovale and severe hypoxaemia. It can also lead to life-threatening circulatory failure. There are many controversial and ...
Tópico(s): Birth, Development, and Health
2013 - Elsevier BV | Archives of cardiovascular diseases
Georgette Gouna, Thameur Rakza, Elaine Kuissi, Thomas Pennaforte, S. Mur, Laurent Storme,
Objective To compare breathing patterns and lung function in the supine, lateral, and prone positions in oxygen-dependent preterm infants. Study design Respiratory function in preterm infants receiving nasal continous positive airway pressure therapy for mild respiratory failure was evaluated by respiratory inductive plethysmography. Infants were randomized to supine, left lateral, and prone positions for 3 hours. A nest provided a semiflexed posture for the infants placed in the left lateral position, ...
Tópico(s): Neuroscience of respiration and sleep
2013 - Elsevier BV | The Journal of Pediatrics
JM Zahm, S Girod de Bentzmann, E. Deneuville, C. Perrot-Minnot, A. Dabadie, F Pennaforte, M. Roussey, Steven Shak, Édith Puchelle,
Recombinant human deoxyribonuclease (rhDNase) has been demonstrated to reduce the viscosity of purulent cystic fibrosis (CF) respiratory mucus, to improve pulmonary function and to reduce the risk of respiratory tract infectious exacerbations, but its effect on mucus transportability has not so far been investigated. The dose-dependent effect of rhDNase was analysed in vitro on mucus transport rate (tr) by ciliary activity and by simulated cough (cough transport (ct)), as well as on mucus viscosity and ...
Tópico(s): Dysphagia Assessment and Management
1995 - European Respiratory Society | European Respiratory Journal
K. Lévesque, Nathalie Morel, Alice Maltret, Gabriel Baron, A. Masseau, P. Orquevaux, Jean‐Charles Piette, François Barrière, J. Le Bidois, L Fermont, Olivier Fain, Arnaud Theulin, F Sassolas, P Pézard, Zahir Amoura, G. Guettrot-Imbert, Delphine Le Mercier, Sophie Georgin‐Lavialle, C. Deligny, É. Hachulla, Luc Mouthon, Philippe Ravaud, E Villain, Damien Bonnet, N. Costedoat‐Chalumeau, H. Bézanahary, Boris Bienvenu, Thomas Gille, P. Blanche, Bernard Bonnotte, P. Cathébras, Christine Christides, Fleur Cohen, Laurence Cohen, Edouard Devaud, Élisabeth Diot, P. Duhaut, Yves Dulac, Bertrand Godeau, V. Gournay, Céline Gronier, Loïc Guillevin, M. Hamidou, Julien Haroche, Gilles Hayem, Florian Heitz, Richard Isnard, M. Jallouli, Anne‐Sophie Korganow, Claire Le Jeunne, François Lhote, Hugues Lucron, Jean‐René Lusson, S Magnier, J. Ninet, Nicolas Pangaud, T. Papo, Jean‐Luc Pellegrin, J L Pennaforte, J. Pouchot, F. Sarrot-Reynauld, N. Schleinitz, P. Sève, Bertrand Stos, D Vital-Durand, B. Wechsler,
Cardiac neonatal lupus syndrome is due to anti-SSA or SSB antibodies and mainly includes congenital heart block (CHB) and dilated cardiomyopathy (DCM). Its optimal management is still debated. We report a large series of autoimmune high degree CHB. Inclusion criteria in this retrospective study were fetuses or neonates with high-degree CHB associated with maternal anti-SSA/SSB antibodies. 214 CHB were included: 202 detected in utero at a median term of 23 weeks' gestation (WG) [range 16 to 39 WG] and ...
Tópico(s): Immunodeficiency and Autoimmune Disorders
2015 - Elsevier BV | Autoimmunity Reviews
Thomas Pennaforte, Ahmed Moussa, Nathalie Loye, Bernard Charlin, Marie‐Claude Audétat,
Background: Helping trainees develop appropriate clinical reasoning abilities is a challenging goal in an environment where clinical situations are marked by high levels of complexity and unpredictability. The benefit of simulation-based education to assess clinical reasoning skills has rarely been reported. More specifically, it is unclear if clinical reasoning is better acquired if the instructor's input occurs entirely after or is integrated during the scenario. Based on educational principles ...
Tópico(s): Simulation-Based Education in Healthcare
2016 - JMIR Publications | JMIR Research Protocols
David Drewery, Colleen Nevison, T. Judene Pretti, Antoine Pennaforte,
Many organisations hire students from cooperative education (co-op) programmes. These organisations are interested in students' performance, particularly in their extra-role performance. Previous studies show that socialisation processes play an important part in establishing adjustment and performance. It may also be the case that students' approach to learning (their motivations, attitudes and strategies) influences the socialisation process, and consequently adjustment and performance. The purpose ...
Tópico(s): Motivation and Self-Concept in Sports
2016 - Routledge | Journal of Education and Work