J. F. Baldwin, Leonard K. Hirshberg, Otto Juettner, W. D. Haines, Alfred Farlow, S. R. Geiser, Ralph Reed, B. F. Lyle,
... A New Method of Separating Saccharose from Dextrose, Pentose, Levulose, Lactose, Maltose, and Invertin When Present in ...
1912 - Gale Group | NCCO-STM 1of2
K.K. Tsuboi, Robert E. Stowell,
1. Methods for the isolation of pentose and desoxypentose nucleic acids from mouse liver tissue, applying gentle extraction and purification procedures were presented. Differential centrifugation techniques were incorporated to ... of guanine in relation to adenine for the pentose nucleic acid, and an excess of adenine over ... to check the chemical methods. 3. Mouse liver pentose nucleic acid was found to be similar to ... Crystalline ribonucleinase was found to hydrolyze the liver pentose nucleic acid incompletely. A preferential hydrolysis of pyrimidine ...
Tópico(s): Biochemical and Molecular Research
1950 - Elsevier BV | Biochimica et Biophysica Acta
... the ultra-violet absorption characteristics of mouse liver pentose and desoxypentose nucleic acids following treatment with acid, ... 3. Extinction values were determined for mouse liver pentose and desoxypentose nucleic acids following specific hydrolytic procedures ... procedures in conjunction with chemical analyses for phosphorus, pentose, and desoxypentose. 1. Nouse avons démontré des changements ... l'absorption charactéristique dans l'ultraviolet des acides pentose- et désoxypentose-nucléiques de foie de souris, après ...
Tópico(s): Viral gastroenteritis research and epidemiology
1950 - Elsevier BV | Biochimica et Biophysica Acta
Sakuzo Fukui, Akira ÔI, Akira Ôbayashi, Kakuo KITAHARA,
1) Pentose fermentation by various lactic acid bacteria can be classified into the following two types : a) Formula (I) ... III) which supposedly involves a new pathway of pentose metabolism. Almost all of the examined organisms metabolized various pentoses according to either formula (I) or (III) exclusively. But, some exceptional strains fermented different pentoses by different schemes. For example, Leuconostoc mesenteroides B07 fermented various pentoses only according to formula (I) and L. thermophilus ...
Tópico(s): Melamine detection and toxicity
1957 - Microbiology Research Foundation | The Journal of General and Applied Microbiology
Samuel Gurin, Dorothy B. Hood,
... to apply the method to a study of pentoses and the nucleic acids.EXPERIMENTAL Pentoses---A number of pentoses were examined by the carbazole procedure as previously ... after treatment with sulfuric acid and carbazole, the pentoses gave rise to colored solutions which, when tested ... 520 and 420 mp for a number of pentoses as well as the calculated ratios EG~O/ ... measured at 520 rnp and the concentration of pentose.The ratios obtained with arabinose, ribose, and lyxose ... can accordingly be readily distinguished from the other pentoses.Identification of Pentose in Nucleosides, Nucleotides, and Nucleic ...
Tópico(s): DNA and Nucleic Acid Chemistry
1941 - Elsevier BV | Journal of Biological Chemistry
Joseph Katz, Bernard R. Landau, Glenn E. Bartsch,
... of triose-P isomerization, the contribution of the pentose cycle to glucose metabolism, and relative outflow from ... the rate of triose-P isomerase, and the pentose cycle contribution under conditions of incomplete isotopic equilibration ... is limited, previously derived methods for evaluating the pentose cycle with the use of glucose-1-14C ... can be applied. 2. The contribution of the pentose cycle was calculated from 14C yields from glucose- ... five methods agreed closely. The contribution of the pentose cycle was correlated with fatty acid synthesis. In ...
Tópico(s): Regulation of Appetite and Obesity
1966 - Elsevier BV | Journal of Biological Chemistry
1. The pentose phosphate pathway in Krebs ascites cells was investigated for regulatory reactions. For comparison, the glycolytic pathway was studied simultaneously. 2. Activities of the pentose phosphate pathway enzymes were low in contrast with ... extending into the steady state. 5. Of the pentose phosphate pathway intermediates, accumulation of 6-phosphogluconate, sedoheptulose ... the steady-state concentration by 2min., whereas the pentose phosphates accumulated linearly. 6. The mass-action ratios ...
Tópico(s): Cancer, Hypoxia, and Metabolism
1969 - Portland Press | Biochemical Journal
... kinetic studies and mode of energy coupling of pentose uptake in various bacterial and yeast strains. Regulation of pentose uptake in both bacteria and yeasts has been ... of other carbohydrates. In addition, genetic analyses of pentose uptake have been overviewed in order to provide insights into the molecular mechanisms underlying pentose uptake and regulation in pentose fermenting micro-organisms. It is evident that the early studies of pentose uptake addressed the queries regarding the mechanism of ...
Tópico(s): Food composition and properties
1971 - Elsevier BV | Journal of Theoretical Biology
H Kather, Madison E. Rivera, Karl Brand,
... of different metabolic pathways the interdependence of the pentose phosphate cycle and lipogenesis in isolated fat-cells ... synthesis was almost abolished. A concomitant decrease in pentose phosphate-cycle activity was observed. Phenazine methosulphate stimulated pentose phosphate-cycle activity about five- to ten-fold ... synthesis. The influence of rotenone on both the pentose phosphate cycle and lipogenesis could be overcome by ... on these pathways. The decreased rate of the pentose phosphate cycle in the presence of rotenone therefore ...
Tópico(s): Metabolomics and Mass Spectrometry Studies
1972 - Portland Press | Biochemical Journal
... because they assume that certain products of the pentose cycle mix freely with those of glycolysis, which ... but calculable fraction of the products of each pentose cycle re‐enters the next cycle, the remainder ... such as the partitioning of material between the pentose cycle and glycolysis, the partitioning of CO 2 output between the pentose and citric acid cycles, the partitioning of the ... lactate, and the degree of recycling from one pentose cycle into the next. In addition, the time ... that in these ganglia (a) recycling in the pentose cycle can be 100% efficient in some incubation ...
Tópico(s): Diet and metabolism studies
1978 - Wiley | Journal of Neurochemistry
The reactions of the anaerobic part of the pentose cycle of carbohydrate metabolism and glycolysis in the ... 7-phosphate formed is an immediate precursor of pentose phosphates in a transketolase reaction with glyceraldehyde 3-phosphate. Hence, during pentose phosphate synthesis from glycolytic products heptulose 1,7- ... 7-phosphate is utilized for the synthesis of pentose phosphates and does not serve as a pool for erythrose 4-phosphate. Under excess of pentose phosphates and the lack of glycolytic products the ...
Tópico(s): Biomedical Research and Pathophysiology
1981 - Pergamon Press | Advances in Enzyme Regulation
... were utilized to calculate the contribution of the pentose cycle to de novo fatty acid synthesis in ... adipose tissue), estimates of glucose flux through the pentose cycle that were based on the relative specific ... the total utilized glucose was metabolized via the pentose cycle in the absence of other exogenous substrates. ... 14CO2 production from [1-14C]glucose by the pentose cycle and the yield of tritium from [3- ... to 72% (glucose + acetate and lactate) of the pentose cycle-derived NADPH was utilized for lipogenesis. Calculations ...
Tópico(s): Lipid metabolism and biosynthesis
1983 - Elsevier BV | Archives of Biochemistry and Biophysics
Aron B. Fisher, J. Reicherter,
Activity of the pentose phosphate pathway of glucose metabolism was measured in isolated granular pneumocytes under a variety of metabolic conditions known to ... or 5-3H for determination of glucose utilization, pentose cycle activity, and partition of CO2 production between mitochondrial and pentose pathways. With control cells, total glucose utilization was ... 19), and 2.2% was metabolized by the pentose cycle. Pentose cycle CO2 production was 7.3 nmoles · hr− ... 5-fold but had no effect on the pentose cycle activity. Phenazine methosulfate (5 μM) had no ...
Tópico(s): Nitric Oxide and Endothelin Effects
1984 - Elsevier BV | Biochemical Pharmacology
Steven A. Belinsky, Lester A. Reinke, Roland W. Scholz, Frederick C. Kauffman, Ronald G. Thurman,
Rates of NADPH production via the pentose phosphate cycle were determined in perfused livers from phenobarbital-treated rats by measuring 14CO2 production from [1-14C]glucose infused in the ... rates of 8.9 mumol/g/hr, stimulated pentose cycle-dependent NADPH production by 21-24 mumol/ ... Fasting for 24 hr prior to perfusion diminished pentose cycle flux by 80% and largely abolished the stimulation of the pentose cycle by p-nitroanisole. In contrast, rates of ... dehydrogenase, decreased rates of NADPH generation via the pentose cycle to 6.9 mumol/g/hr but ...
Tópico(s): Clinical Nutrition and Gastroenterology
1985 - American Society for Pharmacology and Experimental Therapeutics | Molecular Pharmacology
Krishan K. Arora, John P. Longenecker, John F. Williams,
... of the mechanism and quantitative contribution of the pentose phosphate pathway in the glucose metabolism of Morris ... 5123C has an active non-oxidative segment of pentose pathway as judged by its ability to convert ... quantitative criteria, the cells exhibit the L-type pentose pathway reaction sequence rather than the F-type ... carbon into various intermediates and products of the pentose pathway. Intermediary roles for ido octulose mono- and ... by the phosphotransferase enzyme of the L-type pentose pathway. Presence of L-type PP reactions was ...
Tópico(s): Biochemical and Molecular Research
1987 - Elsevier BV | International Journal of Biochemistry
... hexose (d-glucose and d-galactose) and two pentose (d-xylose and d-arabinose) sugars were measured ... mM) sugars, with either the hexoses preceding the pentoses or vice versa. 3. With all treatments, absorption ... hexoses were alike, as were those of the pentoses. Hexose absorption was twice as fast as pentose absorption in jejunum and ileum with both dietary pretreatments, whereas in caecum hexose and pentose rates were similarly high, except when pentose (and its associated fluid transfer) was apparently inhibited ...
Tópico(s): Enzyme function and inhibition
1991 - Elsevier BV | Comparative Biochemistry and Physiology Part A Physiology
Denis Rontein, Martine Dieuaide‐Noubhani, Érick J. Dufourc, Philippe Raymond, Dominique D. Rolin,
... cells. However, the relative fluxes of glycolysis, the pentose-P pathway, and the tricarboxylic acid cycle remained ... cells. However, the relative fluxes of glycolysis, the pentose-P pathway, and the tricarboxylic acid cycle remained ... radioactivity; FW, fresh weight; DW, dry weight; PPP, pentose-phosphate pathway 1The abbreviations used are: PK, pyruvate ... radioactivity; FW, fresh weight; DW, dry weight; PPP, pentose-phosphate pathwaycan be bypassed by pyrophosphate:fructose-6- ... radioactivity; FW, fresh weight; DW, dry weight; PPP, pentose-phosphate pathwayH and13C NMR were used to determine ...
Tópico(s): Plant tissue culture and regeneration
2002 - Elsevier BV | Journal of Biological Chemistry
... of carbohydrate but is now known as the pentose phosphate pathway. After I left Chicago during the ... by TPN were carbon dioxide and an unidentified pentose phosphate. Because carbon dioxide was one of the ... in addition to carbon dioxide, was a new pentose ester, ribulose 5-phosphate, which was then converted to ribose 5-phosphate by a pentose-phosphate isomerase present in our purified dehydrogenase preparations. ... demonstration that their interconversion was catalyzed by a pentose-phosphate isomerase were made possible by the recent ...
Tópico(s): Enzyme function and inhibition
2002 - Elsevier BV | Journal of Biological Chemistry
Begoña Comı́n-Anduix, László G. Boros, Silvia Marín, Joan Boren, Carles Callol-Massot, Josep J. Centelles, Josep Lluı́s Torres, Neus Agell, Sara Bassilian, Marta Cascante,
... distribution, apoptosis, and the activity of key glycolytic/pentose cycle enzymes that control carbon flow for nucleic ... dependent fashion, which correlated with decreased13C incorporation and pentose cycle substrate flow into RNA ribose. This decrease in pentose cycle enzyme activities and carbon flow toward nucleic ... distribution, apoptosis, and the activity of key glycolytic/pentose cycle enzymes that control carbon flow for nucleic ... dependent fashion, which correlated with decreased13C incorporation and pentose cycle substrate flow into RNA ribose. This decrease ...
Tópico(s): Research in Cotton Cultivation
2002 - Elsevier BV | Journal of Biological Chemistry
Gregory Pearce, Clarence A. Ryan,
... indicative of a peptide having different numbers of pentose residues attached (Δ132 mass units) (Fig. 2A, top). ... largest glycosylated species in Peak 1 contains 16 pentose units. The masses found for the various other ... single peptide backbone is decorated with 12–17 pentose units.Fig. 2MALDI-mass spectral analysis of components ... a ladder of species containing various numbers of pentose residues (Fig. 2B, top). Upon hydrolysis, one major ... differences among the various species indicate that 11 pentose residues are present in the largest component of ...
Tópico(s): Plant Stress Responses and Tolerance
2003 - Elsevier BV | Journal of Biological Chemistry
Joan Boren, Wai‐Nang Paul Lee, Sara Bassilian, Josep J. Centelles, Shu Lim, Sayed Ahmed, László G. Boros, Marta Cascante,
... the detection of m1 (recycled lactate through the pentose cycle) and m2 (lactate produced by glycolysis) for the estimation of pentose cycle activity (17Lee W.N. Boros L.G. ... direct oxidation via the oxidative steps of the pentose phosphate pathways and then recycled to glycolysis via the non-oxidative pentose cycle. From these results, we can predict pentose cycle flux relative to the glycolytic flux, and ... Butyrate on Flux Distribution between Glycolysis and the Pentose Cycle—Lactate labeling from [1,2-13C2]glucose ...
Tópico(s): Protein Degradation and Inhibitors
2003 - Elsevier BV | Journal of Biological Chemistry
Richard A. Wilson, Joanna M. Jenkinson, Robert P. Gibson, Jennifer A. Littlechild, Zheng‐Yi Wang, Nicholas J. Talbot,
Article19 July 2007free access Tps1 regulates the pentose phosphate pathway, nitrogen metabolism and fungal virulence Richard A Wilson Richard A Wilson School of Biosciences, University of Exeter, Exeter, UK Search for ... T6P) synthase (Tps1) is responsible for regulating the pentose phosphate pathway, intracellular levels of NADPH and fungal ... of NADPH levels, via regulation of the oxidative pentose phosphate pathway. Furthermore, Tps1 regulates nitrogen utilisation by ... production. (A) Enzyme activities associated with glycolysis, the pentose phosphate pathway and NO3− metabolism from Guy-11 ...
Tópico(s): Plant nutrient uptake and metabolism
2007 - Springer Nature | The EMBO Journal
Chisako USUKI, Yukitaka Kimura, Shuji Adachi,
... Ribose was the most rapidly degraded among the pentoses tested. The degradation of the glucuronic and galacturonic ... proceeded at lower temperatures than that of the pentoses, and was measured at 140, 150 and 160 °C. The degradation processes of the pentoses and hexouronic acids could be expressed by the ... entropy compensation held for the degradation of the pentoses as well as the hexoses, which suggests that ... through a mechanism different from that for the pentoses and hexoses. The molar yield of a pentose ...
Tópico(s): Free Radicals and Antioxidants
2007 - Wiley | Chemical Engineering & Technology
F. Wang, Yi Zhao, Yucun Niu, C. Wang, Maoqing Wang, Y. Li, Changqi Sun,
... dehydrogenase (G6PD), the rate-limiting enzyme for the pentose phosphate pathway, was involved in insulin resistance via ... nicotinamide adenine dinucleotide phosphate, while the roles of pentose were not examined. In the present study, the association of G6PD, pentose, and pentosidine with insulin resistance was investigated in ... OR, n=14) rats. The levels of G6PD, pentose, and pentosidine, and oxidative stress were analyzed in ... increased in the pancreas and liver with upregulated pentose levels in serum, pancreas, and liver of OP ...
Tópico(s): Diabetes and associated disorders
2012 - Thieme Medical Publishers (Germany) | Hormone and Metabolic Research
Thorsten Subtil, Eckhard Boles,
... to ferment D-xylose and L-arabinose the pentose sugars are normally only utilized after depletion of ... This has been attributed to competitive inhibition of pentose uptake by D-glucose as pentose sugars are taken up into yeast cells by ... We wanted to investigate whether D-glucose inhibits pentose utilization only by blocking its uptake or also ... distinguish between inhibitory effects of D-glucose on pentose uptake and pentose catabolism, maltose was used as an alternative carbon source in maltose-pentose co-consumption experiments. Maltose is taken up by ...
Tópico(s): Microbial Metabolic Engineering and Bioproduction
2012 - Springer Science+Business Media | Biotechnology for Biofuels
Z. Spolarics, John J. Spitzer,
Glucose use and pentose cycle activity were determined in freshly isolated rat hepatic endothelial cells 3 hr after an intravenous injection of Escherichia ... glucose use fivefold, whereas glucose oxidation in the pentose cycle was elevated from 0.2 to 1. ... myristate 13-acetate (10 −6 mol/L) increased pentose cycle activity twofold and eightfold, respectively. Phorbol 12- ... fold increase in the glucose flux through the pentose cycle in cells from saline- and lipopolysaccharide-treated ... or t-butyl hydroperoxide-induced increase in the pentose cycle activity with no marked effects on glycolysis. ...
Tópico(s): Eicosanoids and Hypertension Pharmacology
1993 - Lippincott Williams & Wilkins | Hepatology
Kenneth McCormick, Xudong Wang, Gail J. Mick,
... HSD1 would be metabolically interconnected with the cytosolic pentose pathway because this pathway is the primary producer ... test this theory, 11 β-HSD1 activity and pentose pathway were simultaneously measured in isolated intact rodent adipocytes. Established inhibitors of NAPDH production via the pentose pathway (dehydroandrostenedione or norepinephrine) inhibited 11 β-HSD1 ... HSD1 (corticosterone or 11-dehydrocorticosterone) inhibited or increased pentose flux, respectively, demonstrating metabolic interconnectivity. Using isolated intact ...
Tópico(s): Pharmacological Effects of Natural Compounds
2005 - Elsevier BV | Journal of Biological Chemistry
Nades Palaniyar, Jeya Nadesalingam, Howard Clark, Michael J. Shih, Alister W. Dodds, Kenneth B. M. Reid,
... protein mannose-binding lectin, could recognize nucleic acids, pentose-based anionic phosphate polymers. Here we show that ... of origins, including bacteria, mice, and synthetic oligonucleotides. Pentoses, such as arabinose, ribose, and deoxyribose, inhibit the ... D, and biologically relevant d-forms of the pentoses are better competitors than the l-forms. In ... protein mannose-binding lectin, could recognize nucleic acids, pentose-based anionic phosphate polymers. Here we show that ... of origins, including bacteria, mice, and synthetic oligonucleotides. Pentoses, such as arabinose, ribose, and deoxyribose, inhibit the ...
Tópico(s): Neutrophil, Myeloperoxidase and Oxidative Mechanisms
2004 - Elsevier BV | Journal of Biological Chemistry