J. F. Baldwin, Leonard K. Hirshberg, Otto Juettner, W. D. Haines, Alfred Farlow, S. R. Geiser, Ralph Reed, B. F. Lyle,
... A New Method of Separating Saccharose from Dextrose, Pentose, Levulose, Lactose, Maltose, and Invertin When Present in ...
1912 - Gale Group | NCCO-STM 1of2
Justyna Ruchała, Andriy А. Sibirny,
Pentose sugars are widespread in nature and two of them, D-xylose and L-arabinose belong to ... not surprising that metabolism and bioconversion of these pentoses attract much attention. Several different pathways of D- ... common and really ubiquitous though not so abundant pentoses, D-ribose and 2-deoxy-D-ribose, the ... example of endogenous metabolism whereas metabolism of other pentoses, including xylose and L-arabinose, represents examples of ... not constituents of yeast cells. As a rule, pentose degradation by the wild-type strains of microorganisms ...
Tópico(s): Enzyme Structure and Function
2020 - Oxford University Press | FEMS Microbiology Reviews
Eugenio Frixione, Lourdes Ruiz-Zamarripa,
... some kind of carbohydrate suspected to be a pentose (19Hammarsten O. Zur kenntnis der nucleoproteide.Z. Physiol. ... yeast) and the sugar in each case (a pentose in yeast versus what was by then supposed ... Moreover, this same work provided evidence that the pentose contained in yeast nucleic acid, so far believed ... argued, based upon various considerations, that "Since the pentoses of guanylic acid and of yeast nucleic acid ... that of] inosinic acid, the nature of [the] pentose in this nucleic acid may now be regarded ...
Tópico(s): RNA and protein synthesis mechanisms
2019 - Elsevier BV | Journal of Biological Chemistry
Matthew T. Campbell, Dazhe Chen, Gary L. Glish,
... of distinguishing an exhaustive list of underivatized D-pentoses with only a mass spectrometer. Electrospray ionization (ESI) of a solution containing a pentose and a lithium salt yields [Pentose + Li]+. These lithiated pentoses adduct water in a quadrupole ion trap. The ... water adduction is unique for several of the pentose isomers. Additionally, there are multiple potential gas-phase lithiation sites to form [Pentose + Li]+. A mixture of ions with at least ... non-adducting) lithiation site is formed for each pentose. The water adduction reaction rate along with the ...
Tópico(s): Mass Spectrometry Techniques and Applications
2017 - American Chemical Society | Journal of the American Society for Mass Spectrometry
Pentoses, including xylose and arabinose, are the second most prevalent sugars in lignocellulosic biomass that can be ... of high-value chemicals and biofuels, its native pentose metabolism is poorly understood. Our previous study demonstrated ... native sugar-specific transporters for activating the dormant pentose metabolism in Y. lipolytica By screening a comprehensive set of 16 putative pentose-specific transporters, we identified two candidates, YALI0C04730p and ... Overall, this study sheds light on the cryptic pentose metabolism of Y. lipolytica and, further, helps guide ...
Tópico(s): Enzyme Catalysis and Immobilization
2017 - American Society for Microbiology | Applied and Environmental Microbiology
Mark E. Corkins, Stevin Wilson, Jean‐Christophe Cocuron, Ana Paula Alonso, Amanda Bird,
Glycolysis and the pentose phosphate pathway both play a central role in the degradation of glucose in all domains of life. Another metabolic ... the two-step conversion of glucose into the pentose phosphate pathway intermediate 6-phosphogluconate. Despite the presence ... zwf1, which encode the first enzyme in the pentose phosphate pathway, have a more severe growth phenotype ... Idn1 act together to shunt glucose into the pentose phosphate pathway, creating an alternative route for directing glucose into the pentose phosphate pathway that bypasses hexokinase and the rate- ...
Tópico(s): Genetic Neurodegenerative Diseases
2017 - Elsevier BV | Journal of Biological Chemistry
Produção Nacional
Revisado por pares
Bárbara Catarina Bastos de Freitas, Eduarda Holz Brächer, Etiele Greque de Morais, Daniel Ibraim Pires Atala, Michele Greque de Morais, Jorge Alberto Vieira Costa,
... search for alternative carbon sources for microalgae cultivation, pentoses can be considered interesting alternatives since the most ... is lignocellulosic waste, which contains significant quantities of pentoses. However, the use of pentoses (C5) in the cultivation of microalgae is still ... and only recently the first metabolic pathway for pentose absorption in microalgae was proposed. So, the objective ... work was to evaluate if the use of pentoses affects the growth and carbohydrates content of Chlorella ...
Tópico(s): Biodiesel Production and Applications
2017 - Taylor & Francis | Environmental Technology
Ludmilla Aristilde, Ian A. Lewis, Junyoung O. Park, Joshua D. Rabinowitz,
... of the cellulosic hexose sugar (glucose) and hemicellulosic pentose sugars (xylose and arabinose) in the anaerobic soil ... was preferentially used as the carbon source. Assimilated pentose sugars accumulated in pentose phosphate pathway (PPP) intermediates with minimal flux into ... and arabinose revealed an unexpected hierarchy among the pentose sugars, with arabinose utilized preferentially over xylose. The phosphoketolase pathway (PKP) provides an alternative route of pentose catabolism in C. acetobutylicum that directly converts xylulose- ...
Tópico(s): Microbial Metabolites in Food Biotechnology
2014 - American Society for Microbiology | Applied and Environmental Microbiology
Fan Wang, Yi Zhao, Yucun Niu, C. Wang, Maoqing Wang, Y. Li, Changqi Sun,
... dehydrogenase (G6PD), the rate-limiting enzyme for the pentose phosphate pathway, was involved in insulin resistance via ... nicotinamide adenine dinucleotide phosphate, while the roles of pentose were not examined. In the present study, the association of G6PD, pentose, and pentosidine with insulin resistance was investigated in ... OR, n=14) rats. The levels of G6PD, pentose, and pentosidine, and oxidative stress were analyzed in ... increased in the pancreas and liver with upregulated pentose levels in serum, pancreas, and liver of OP ...
Tópico(s): Diabetes and associated disorders
2012 - Thieme Medical Publishers (Germany) | Hormone and Metabolic Research
Thorsten Subtil, Eckhard Boles,
... to ferment D-xylose and L-arabinose the pentose sugars are normally only utilized after depletion of ... This has been attributed to competitive inhibition of pentose uptake by D-glucose as pentose sugars are taken up into yeast cells by ... We wanted to investigate whether D-glucose inhibits pentose utilization only by blocking its uptake or also ... distinguish between inhibitory effects of D-glucose on pentose uptake and pentose catabolism, maltose was used as an alternative carbon source in maltose-pentose co-consumption experiments. Maltose is taken up by ...
Tópico(s): Microbial Metabolic Engineering and Bioproduction
2012 - Springer Science+Business Media | Biotechnology for Biofuels
Chisako USUKI, Yukitaka Kimura, Shuji Adachi,
... Ribose was the most rapidly degraded among the pentoses tested. The degradation of the glucuronic and galacturonic ... proceeded at lower temperatures than that of the pentoses, and was measured at 140, 150 and 160 °C. The degradation processes of the pentoses and hexouronic acids could be expressed by the ... entropy compensation held for the degradation of the pentoses as well as the hexoses, which suggests that ... through a mechanism different from that for the pentoses and hexoses. The molar yield of a pentose ...
Tópico(s): Free Radicals and Antioxidants
2007 - Wiley | Chemical Engineering & Technology
Richard A. Wilson, Joanna M. Jenkinson, Robert P. Gibson, Jennifer A. Littlechild, Zheng‐Yi Wang, Nicholas J. Talbot,
Article19 July 2007free access Tps1 regulates the pentose phosphate pathway, nitrogen metabolism and fungal virulence Richard A Wilson Richard A Wilson School of Biosciences, University of Exeter, Exeter, UK Search for ... T6P) synthase (Tps1) is responsible for regulating the pentose phosphate pathway, intracellular levels of NADPH and fungal ... of NADPH levels, via regulation of the oxidative pentose phosphate pathway. Furthermore, Tps1 regulates nitrogen utilisation by ... production. (A) Enzyme activities associated with glycolysis, the pentose phosphate pathway and NO3− metabolism from Guy-11 ...
Tópico(s): Plant nutrient uptake and metabolism
2007 - Springer Nature | The EMBO Journal
Kenneth McCormick, Xudong Wang, Gail J. Mick,
... HSD1 would be metabolically interconnected with the cytosolic pentose pathway because this pathway is the primary producer ... test this theory, 11 β-HSD1 activity and pentose pathway were simultaneously measured in isolated intact rodent adipocytes. Established inhibitors of NAPDH production via the pentose pathway (dehydroandrostenedione or norepinephrine) inhibited 11 β-HSD1 ... HSD1 (corticosterone or 11-dehydrocorticosterone) inhibited or increased pentose flux, respectively, demonstrating metabolic interconnectivity. Using isolated intact ...
Tópico(s): Pharmacological Effects of Natural Compounds
2005 - Elsevier BV | Journal of Biological Chemistry
Nades Palaniyar, Jeya Nadesalingam, Howard Clark, Michael J. Shih, Alister W. Dodds, Kenneth B. M. Reid,
... protein mannose-binding lectin, could recognize nucleic acids, pentose-based anionic phosphate polymers. Here we show that ... of origins, including bacteria, mice, and synthetic oligonucleotides. Pentoses, such as arabinose, ribose, and deoxyribose, inhibit the ... D, and biologically relevant d-forms of the pentoses are better competitors than the l-forms. In ... protein mannose-binding lectin, could recognize nucleic acids, pentose-based anionic phosphate polymers. Here we show that ... of origins, including bacteria, mice, and synthetic oligonucleotides. Pentoses, such as arabinose, ribose, and deoxyribose, inhibit the ...
Tópico(s): Neutrophil, Myeloperoxidase and Oxidative Mechanisms
2004 - Elsevier BV | Journal of Biological Chemistry
Gregory Pearce, Clarence A. Ryan,
... indicative of a peptide having different numbers of pentose residues attached (Δ132 mass units) (Fig. 2A, top). ... largest glycosylated species in Peak 1 contains 16 pentose units. The masses found for the various other ... single peptide backbone is decorated with 12–17 pentose units.Fig. 2MALDI-mass spectral analysis of components ... a ladder of species containing various numbers of pentose residues (Fig. 2B, top). Upon hydrolysis, one major ... differences among the various species indicate that 11 pentose residues are present in the largest component of ...
Tópico(s): Plant Stress Responses and Tolerance
2003 - Elsevier BV | Journal of Biological Chemistry
Joan Boren, Wai‐Nang Paul Lee, Sara Bassilian, Josep J. Centelles, Shu Lim, Sayed Ahmed, László G. Boros, Marta Cascante,
... the detection of m1 (recycled lactate through the pentose cycle) and m2 (lactate produced by glycolysis) for the estimation of pentose cycle activity (17Lee W.N. Boros L.G. ... direct oxidation via the oxidative steps of the pentose phosphate pathways and then recycled to glycolysis via the non-oxidative pentose cycle. From these results, we can predict pentose cycle flux relative to the glycolytic flux, and ... Butyrate on Flux Distribution between Glycolysis and the Pentose Cycle—Lactate labeling from [1,2-13C2]glucose ...
Tópico(s): Protein Degradation and Inhibitors
2003 - Elsevier BV | Journal of Biological Chemistry
... of carbohydrate but is now known as the pentose phosphate pathway. After I left Chicago during the ... by TPN were carbon dioxide and an unidentified pentose phosphate. Because carbon dioxide was one of the ... in addition to carbon dioxide, was a new pentose ester, ribulose 5-phosphate, which was then converted to ribose 5-phosphate by a pentose-phosphate isomerase present in our purified dehydrogenase preparations. ... demonstration that their interconversion was catalyzed by a pentose-phosphate isomerase were made possible by the recent ...
Tópico(s): Enzyme function and inhibition
2002 - Elsevier BV | Journal of Biological Chemistry
Denis Rontein, Martine Dieuaide‐Noubhani, Érick J. Dufourc, Philippe Raymond, Dominique D. Rolin,
... cells. However, the relative fluxes of glycolysis, the pentose-P pathway, and the tricarboxylic acid cycle remained ... cells. However, the relative fluxes of glycolysis, the pentose-P pathway, and the tricarboxylic acid cycle remained ... radioactivity; FW, fresh weight; DW, dry weight; PPP, pentose-phosphate pathway 1The abbreviations used are: PK, pyruvate ... radioactivity; FW, fresh weight; DW, dry weight; PPP, pentose-phosphate pathwaycan be bypassed by pyrophosphate:fructose-6- ... radioactivity; FW, fresh weight; DW, dry weight; PPP, pentose-phosphate pathwayH and13C NMR were used to determine ...
Tópico(s): Plant tissue culture and regeneration
2002 - Elsevier BV | Journal of Biological Chemistry
Begoña Comín‐Anduix, László G. Boros, Silvia Marín, Joan Boren, Carles Callol-Massot, Josep J. Centelles, Josep Lluı́s Torres, Neus Agell, Sara Bassilian, Marta Cascante,
... distribution, apoptosis, and the activity of key glycolytic/pentose cycle enzymes that control carbon flow for nucleic ... dependent fashion, which correlated with decreased13C incorporation and pentose cycle substrate flow into RNA ribose. This decrease in pentose cycle enzyme activities and carbon flow toward nucleic ... distribution, apoptosis, and the activity of key glycolytic/pentose cycle enzymes that control carbon flow for nucleic ... dependent fashion, which correlated with decreased13C incorporation and pentose cycle substrate flow into RNA ribose. This decrease ...
Tópico(s): Research in Cotton Cultivation
2002 - Elsevier BV | Journal of Biological Chemistry
... the oxidative and the nonoxidative branches of the pentose phosphate pathway blocked the stimulation of glucose-6- ... the oxidative and the nonoxidative branches of the pentose phosphate pathway blocked the stimulation of glucose-6- ... whether this effect requires glucose metabolism through the pentose phosphate pathway. If this pathway is important for ... formation of fructose 6-phosphate.When both the pentose phosphate pathway and phosphoglucoisomerase were inhibited with 6- ... the fact that the nonoxidative branch of the pentose phosphate pathway was blocked suggests that the pentose ...
Tópico(s): Amino Acid Enzymes and Metabolism
2001 - Elsevier BV | Journal of Biological Chemistry
Francesca Salvemini, Annamaria Franzè, Angela Iervolino, Stefania Filosa, Salvatore Salzano, Matilde Valeria Ursini,
... dehydrogenase (G6PD) is the key enzyme of the pentose phosphate pathway that is responsible for the generation ... dehydrogenase (G6PD) is the key enzyme of the pentose phosphate pathway that is responsible for the generation ... both GSH and catalase is produced by the pentose phosphate pathway (9Cohen G. Hochstein P. Biochemistry. 1963; ... the first and rate-limiting enzyme of the pentose phosphate pathway, has long been regarded as important ... peroxidase, catalase, or 6PGD (the second enzyme of pentose phosphate pathway) remain unchanged. Furthermore, these cells feature ...
Tópico(s): Heme Oxygenase-1 and Carbon Monoxide
1999 - Elsevier BV | Journal of Biological Chemistry
... treatment thermal treatment. Part 4 Microbial uptake of pentoses: mode of sugar uptake pentose uptake in yeast pentose uptake in bacteria regulation of pentose uptake genetic studies on pentose uptake. Part 5 Microbial metabolism of pentoses: metabolism of D-xylose regulation of D-xylose ... production kinetics of growth and product formation simultaneous pentose isomerization and fermentation whole cell immobilization coculture performance ... and organic acids. Part 13 Genetic improvement of pentose fermenting microorganisms: screening and mutagenesis genetic recombination gene ...
Tópico(s): Enzyme Catalysis and Immobilization
1995 - Elsevier BV | Progress in industrial microbiology
Z. Spolarics, John J. Spitzer,
Glucose use and pentose cycle activity were determined in freshly isolated rat hepatic endothelial cells 3 hr after an intravenous injection of Escherichia ... glucose use fivefold, whereas glucose oxidation in the pentose cycle was elevated from 0.2 to 1. ... myristate 13-acetate (10 −6 mol/L) increased pentose cycle activity twofold and eightfold, respectively. Phorbol 12- ... fold increase in the glucose flux through the pentose cycle in cells from saline- and lipopolysaccharide-treated ... or t-butyl hydroperoxide-induced increase in the pentose cycle activity with no marked effects on glycolysis. ...
Tópico(s): Eicosanoids and Hypertension Pharmacology
1993 - Lippincott Williams & Wilkins | Hepatology
... hexose (d-glucose and d-galactose) and two pentose (d-xylose and d-arabinose) sugars were measured ... mM) sugars, with either the hexoses preceding the pentoses or vice versa. 3. With all treatments, absorption ... hexoses were alike, as were those of the pentoses. Hexose absorption was twice as fast as pentose absorption in jejunum and ileum with both dietary pretreatments, whereas in caecum hexose and pentose rates were similarly high, except when pentose (and its associated fluid transfer) was apparently inhibited ...
Tópico(s): Enzyme function and inhibition
1991 - Elsevier BV | Comparative Biochemistry and Physiology Part A Physiology
Krishan K. Arora, John P. Longenecker, John F. Williams,
... of the mechanism and quantitative contribution of the pentose phosphate pathway in the glucose metabolism of Morris ... 5123C has an active non-oxidative segment of pentose pathway as judged by its ability to convert ... quantitative criteria, the cells exhibit the L-type pentose pathway reaction sequence rather than the F-type ... carbon into various intermediates and products of the pentose pathway. Intermediary roles for ido octulose mono- and ... by the phosphotransferase enzyme of the L-type pentose pathway. Presence of L-type PP reactions was ...
Tópico(s): Biochemical and Molecular Research
1987 - Elsevier BV | International Journal of Biochemistry
Steven A. Belinsky, Lester A. Reinke, Roland W. Scholz, Frederick C. Kauffman, Ronald G. Thurman,
Rates of NADPH production via the pentose phosphate cycle were determined in perfused livers from phenobarbital-treated rats by measuring 14CO2 production from [1-14C]glucose infused in the ... rates of 8.9 mumol/g/hr, stimulated pentose cycle-dependent NADPH production by 21-24 mumol/ ... Fasting for 24 hr prior to perfusion diminished pentose cycle flux by 80% and largely abolished the stimulation of the pentose cycle by p-nitroanisole. In contrast, rates of ... dehydrogenase, decreased rates of NADPH generation via the pentose cycle to 6.9 mumol/g/hr but ...
Tópico(s): Clinical Nutrition and Gastroenterology
1985 - American Society for Pharmacology and Experimental Therapeutics | Molecular Pharmacology
Aron B. Fisher, J. Reicherter,
Activity of the pentose phosphate pathway of glucose metabolism was measured in isolated granular pneumocytes under a variety of metabolic conditions known to ... or 5-3H for determination of glucose utilization, pentose cycle activity, and partition of CO2 production between mitochondrial and pentose pathways. With control cells, total glucose utilization was ... 19), and 2.2% was metabolized by the pentose cycle. Pentose cycle CO2 production was 7.3 nmoles · hr− ... 5-fold but had no effect on the pentose cycle activity. Phenazine methosulfate (5 μM) had no ...
Tópico(s): Nitric Oxide and Endothelin Effects
1984 - Elsevier BV | Biochemical Pharmacology
... were utilized to calculate the contribution of the pentose cycle to de novo fatty acid synthesis in ... adipose tissue), estimates of glucose flux through the pentose cycle that were based on the relative specific ... the total utilized glucose was metabolized via the pentose cycle in the absence of other exogenous substrates. ... 14CO2 production from [1-14C]glucose by the pentose cycle and the yield of tritium from [3- ... to 72% (glucose + acetate and lactate) of the pentose cycle-derived NADPH was utilized for lipogenesis. Calculations ...
Tópico(s): Lipid metabolism and biosynthesis
1983 - Elsevier BV | Archives of Biochemistry and Biophysics