Petra Cetkovská, Michaela Komorousová, Iva Lomicová,
... and IgG antibodies and coexistent lung cancer Petra Cetkovská, Corresponding Author Petra Cetkovská Medical Faculty and Teaching Hospital Pilsen, Department ... RepublicSearch for more papers by this author Petra Cetkovská, Corresponding Author Petra Cetkovská Medical Faculty and Teaching Hospital Pilsen, Department of ... Pilsen, Czech RepublicAddress correspondence and reprint requests to: Petra Cetkovská, MD, PhD, Professor, Medical Faculty and Teaching Hospital ...
Tópico(s): Coagulation, Bradykinin, Polyphosphates, and Angioedema
2014 - Wiley | Dermatologic Therapy
Jan Říčař, Karel Pizinger, Petra Cetkovská,
... fnplzen.czSearch for more papers by this authorPetra Cetkovska MD, PhD, Petra Cetkovska MD, PhD Department of Dermatology and Venereology, ... fnplzen.czSearch for more papers by this authorPetra Cetkovska MD, PhD, Petra Cetkovska MD, PhD Department of Dermatology and Venereology, Charles ...
Tópico(s): Nail Diseases and Treatments
2012 - Wiley | International Journal of Dermatology
Karel Pizinger, Petra Cetkovská, Denisa Kacerovská, Magda Kumpova,
Auteur(s) : Karel Pizinger, Petra Cetkovska, Denisa Kacerovska, Magda Kumpova Department of Dermatology and Venereology, Medical Faculty, Charles University and University Hospital, Dr. E. Benese 13, ...
Tópico(s): Insect and Pesticide Research
2009 - John Libbey Eurotext | European Journal of Dermatology
Amy S. Paller, Marieke M.B. Seyger, Gabriel A. Magariños, Andreas Pinter, Jennifer Clay Cather, Claudia Rodriguez-Capriles, Danting Zhu, Najwa Somani, Alyssa Garrelts, Kim Papp, Gabriel A. Magariños, Ricardo Galimberti, Diego Oscar Viola, Paula Carolina Luna, Charles Lynde, Danielle Marcoux, Vimal H. Prajapati, Ajith Cy, Petr Arenberger, Stanislava Polášková, Hans Buckova, Jirina Bartonová, Petra Cetkovská, Jana Hercogová, J.‐P. Lacour, Alice Phan, Michael Sticherling, Petra Staubach, Margrit Simon, Andreas Pinter, Nina Magnolo, Piroska Dosa, Judit Noll, Éva Remenyik, Lajos Kemény, Noémi Bakos, Claudia Bernabe del Rio, Mirna Toledo‐Bahena, Minerva Gómez Flores, Zamira Barragan Estudillo, Marieke M.B. Seyger, Jolanta Węgłowska, Elżbieta Szymańska, Andrzej Kaszuba, Nikolay N. Murashkin, Asuncion Vicente Villa, R Laguna, R. Rivera, Jerry Bagel, John Browning, Michael Bukhalo, Jennifer Clay Cather, Alma Cruz Santana, Boni E. Elewski, Seth Forman, José González-Chávez, Scott Gottlieb, Holly Hake Harris, Jessica Kaffenberger, Pearl Kwong, Sabre Leitenberger, Aída Lugo‐Somolinos, A. Yasmine Kirkorian, Kari A. Martin, Amy S. Paller, David M. Pariser, Phoebe Rich, Adena E. Rosenblatt, Lucia Seminario‐Vidal, Elaine C. Siegfried, Jeffrey B. Travers, Pedro Vendrell-Benito, Jamie Weisman, Lara Wine Lee, Matthew Zook, Samuel Sanches-Rivera, Vivian Laquer,
About 1% of children and adolescents worldwide are affected by plaque psoriasis.To evaluate the long-term efficacy and safety of ixekizumab for pediatric patients with moderate to severe psoriasis.This multicenter randomized clinical trial (IXORA-PEDS) evaluated pediatric patients with plaque psoriasis. Participants were aged 6 years to younger than 18 years; had moderate to severe psoriasis, which was defined as Psoriasis Area and Severity Index (PASI) of 12 or higher, static Physician's Global Assessment ( ...
Tópico(s): Autoimmune and Inflammatory Disorders Research
2022 - American Medical Association | JAMA Dermatology
Petra Cetkovská, Karel Pizinger, Petr Cetkovský,
High-dose cytosine arabinoside (HDAC) is being used increasingly to treat haematological malignancies. The therapy is associated with various non-haematological negative side-effects, frequently involving the skin.Our aim was to evaluate the actual occurrence of adverse skin reactions to HDAC over the 10-year period from 1989 to 1999.One hundred and seventy-two subjects, 118 with acute myelogenous leukaemia and 54 with acute lymphoblastic leukaemia, between 16 and 71 years of age were treated with ...
Tópico(s): Cutaneous lymphoproliferative disorders research
2002 - Wiley | Journal of the European Academy of Dermatology and Venereology
Petra Cetkovská, Karel Pizinger,
Clinical and Experimental DermatologyVolume 28, Issue 3 p. 328-329 Childhood pemphigus associated with montelukast administration P. Cetkovská, P. Cetkovská Department of Dermatology, Charles University Hospital, Pilsen, Czech RepublicSearch for more papers by this authorK. Pizinger, K. Pizinger Department of Dermatology, Charles University Hospital, Pilsen, Czech RepublicSearch for more papers by this author P. Cetkovská, P. Cetkovská Department of Dermatology, Charles University Hospital, Pilsen, ...
Tópico(s): Coagulation, Bradykinin, Polyphosphates, and Angioedema
2003 - Oxford University Press | Clinical and Experimental Dermatology
Denisa Kacerovská, Karel Pizinger, Magda Kumpova, Petra Cetkovská,
The patient, a 30‐year‐old man with numerous genital condylomata acuminata (CA), has had unsuccessful treatment with liquid nitrogen, 20% podophyllin, and repeated 0.5% podophyllotoxin solution with 5% imiquimod ( Figure 1 ). Before the appearance of CA, he experienced acute orchiepididimitis and a Candida infection . The patient was immunologically examined, and the lower level of lymphocytes, slightly reduced level of IgM, and C4 complement were revealed. Results from a human immunodeficiency virus examination ...
Tópico(s): Pediatric health and respiratory diseases
2007 - Wiley | SKINmed Dermatology for the Clinician
Petra Cetkovská, Karel Pizinger,
Abstract A 39‐year‐old female patient with systemic lupus erythematosus was treated with terbinafine for onychomycosis. After only 7 days of treatment with 250 mg terbinafine, a widespread severe erythematous eruption developed. The results of clinical, histological and immunofluorescent examinations confirmed the diagnosis of coexisting subacute and systemic lupus erythematosus. The patient was treated with drug withdrawal and administration of cyclosporine and methylprednisolone. One year later, ...
Tópico(s): Antifungal resistance and susceptibility
2006 - Wiley | International Journal of Dermatology
Stan Pavel, Frans van Nieuwpoort, H. van der Meulen, Coby Out, Karel Pizinger, Petra Cetkovská, Nico P.M. Smit, Henk K. Koerten,
Dysplastic naevi (DN) are a known risk factor for malignant melanoma. Their occurrence is closely connected with the degree of skin pigmentation. People with a light complexion are more likely to develop DN than dark-skinned individuals. We examined the proposition that DN exhibit altered melanin formation, which may be involved in their malignant transformation. X-ray microanalysis was used to study the composition of melanosomes from DN and to compare the results with those obtained from melanomas, ...
Tópico(s): Cutaneous Melanoma Detection and Management
2004 - Elsevier BV | European Journal of Cancer
Jan Nico Bouwes Bavinck, Catherine Α. Harwood, Roel E. Genders, Hermina C. Wisgerhof, Elsemieke I. Plasmeijer, L. Mitchell, Edit Olasz, Daniel D. Mosel, Madeline S. Pokorney, Andreas L. Serra, Laurence Feldmeyer, Katrin Baumann Conzett, Stefano Piaserico, Anna Belloni Fortina, Katharina Jähn, Alexandra Geusau, M. Gerritsen, Deniz Seçkin, A. Tülin Güleç, Petra Cetkovská, Jan Říčař, Beata Imko‐Walczuk, Charlotte M. Proby, Günther F.L. Hofbauer,
Organ transplant recipients (OTR) are at high risk for cutaneous squamous cell carcinomas (SCC). We aimed to define clinically meaningful patient-reported warning signals predicting the presence of invasive SCC. Patient-reported signs and symptoms of 812 consecutively biopsied skin lesions from 410 OTR were determined by questionnaire and physical examination and related to the subsequent biopsy-proven diagnoses. Receiver-operating characteristic (ROC) curve analyses were used as a measure of distinction ...
Tópico(s): Cutaneous Melanoma Detection and Management
2014 - Elsevier BV | American Journal of Transplantation
Deniz Seçkin, Stéphane Barète, Sylvie Euvrard, C. Françès, Jean Kanitakis, Alexandra Geusau, V. del Mármol, Catherine Α. Harwood, Charlotte M. Proby, Imran Ali, A. Tülin Güleç, Elıf Durukan, Célèste Lebbé, Mauro Alaibac, Emmanuel Laffitte, Stacey Cooper, Jan Nico Bouwes Bavinck, Gillian Murphy, Carlos Ferrándiz, Cato Mørk, Petra Cetkovská, Werner Kempf, Günther F.L. Hofbauer,
Primary cutaneous posttransplant lymphoproliferative disorders (PTLD) are rare. This retrospective, multicenter study of 35 cases aimed to better describe this entity. Cases were (re)-classified according to the WHO-EORTC or the WHO 2008 classifications of lymphomas. Median interval between first transplantation and diagnosis was 85 months. Fifty-seven percent of patients had a kidney transplant. Twenty-four cases (68.6%) were classified as primary cutaneous T cell lymphoma (CTCL) and 11 (31.4%) as primary ...
Tópico(s): Nail Diseases and Treatments
2013 - Elsevier BV | American Journal of Transplantation
Petr Cetkovský, Vladimír Koza, Petra Cetkovská, M Švojgrová,
Tópico(s): Vascular Tumors and Angiosarcomas
1998 - Springer Nature | Bone Marrow Transplantation
William A. Marston, William J. Ennis, John C Lantis, Robert S. Kirsner, Robert D. Galiano, Wolfgang Vanscheidt, Sabine A. Eming, Marcin Malka, D. Innes Cargill, Jaime E. Dickerson, Herbert B. Slade, Charles A. Andersen, Caesar A. Anderson, Petr Arenberger, Roland Aschoff, Matthias Augustin, Noémi Bakos, Hilde Beele, An Bervoets, Joseph Cavorsi, Shawn Cazzell, Petra Cetkovská, J. Randolph Clements, Emily A. Cook, Kenneth Deck, Arlette De Conninck, Marc Despatis, Yadwinder S. Dhillon, Joachim Dissemond, Cyaandi Dove, Steffen Emmert, Sabine A. Eming, William J. Ennis, George L. Enriquez, Alik Farber, Olga Filipovska, Robert G. Frykberg, Joel J. Gagnon, Robert D. Galiano, Tobias George, Vincent D. Giacalone, Ian L. Gordon, Tomasz Grzela, Csaba Hajdú, Jason R. Hanft, Bernhard Homey, Douglas B. Hood, Thomas Horn, Juan Carlos Jiménez, Michael Juenger, David Keast, Lajos Kemény, Paul J. Kim, Robert S. Kirsner, Marek Kotala, John C Lantis, Laszlo Lauf, Lawrence A. Lavery, Holger Lawall, Peter F. Lawrence, Marcin Malka, William A. Marston, Astrid Matejkova, Perry Mayer, Jacek Mikosiński, Michael M. Molyneaux, Michael F. Moore, Eliot N. Mostow, Travis A. Motley, Edina Nemes, Vera Pavlasova, Sven Quist, Éva Remenyik, Alexander M. Reyzelman, Rita Rez, Paul Rock, Thomas Ruzicka, Zbigniew Rybak, Karry Ann Shebetka, Kenneth K. Shimozaki, Marian Simka, Markus Stüecker, David Stuchlik, Paweł Świercz, John Tassone, K. Twardowska-Saucha, Carl Van Gils, Wolfgang Vanscheidt, István Várkonyi, Mher Vartivarian, Vladimı́r Vašků, Dean Vayser, Jodi Walters, Michael Weichenthal, Stephanie Wu, Jonathan M. Zenilman, Radka Zimolova, Tomasz Zubilewicz,
Abstract Objective The objective of this study was to characterize factors associated with closure of venous leg ulcers (VLUs) in a pooled analysis of subjects from three randomized clinical trials. Methods Closure of VLUs after treatment with HP802-247, an allogeneic living cell therapy consisting of growth-arrested human keratinocytes and fibroblasts, vs standard therapy with compression bandaging was evaluated in three phase 3 clinical trials of similar design. Two trials enrolled subjects with VLUs ranging ...
Tópico(s): Pressure Ulcer Prevention and Management
2017 - Elsevier BV | Journal of Vascular Surgery Venous and Lymphatic Disorders
Martina Kojanová, Jorga Fialová, Petra Cetkovská, Spyridon Gkalpakiotis, Jitka Jirčíková, Tomáš Doležal, Petr Arenberger,
Abstract Background BIOREP is a Czech registry of psoriatic patients on biological treatment in a clinical setting. We describe the characteristics of patients with psoriasis at the time of enrollment and present comparisons with published data from other national registries. Methods We analyzed the cohort of patients treated with biologics between May 2005 and May 2015. Demographic data, previous therapies, comorbidities, and severity of psoriasis were compared with data from other registries – DERMBIO , ...
Tópico(s): Rheumatoid Arthritis Research and Therapies
2017 - Wiley | International Journal of Dermatology
Spyridon Gkalpakiotis, Petra Cetkovská, Petr Arenberger, Tomáš Doležal, Monika Arenbergerová, Barbora Velacková, Jorga Fialová, Martina Kojanová,
Risankizumab has been approved for the treatment of moderate-to-severe plaque psoriasis; however, real-life data are limited. Our objectives were to evaluate the effectiveness and safety of risankizumab and its impact on the quality of life of patients with psoriasis in a real-world setting. We retrospectively analyzed 154 patients from 18 centers in the Czech Republic who had undergone biologic therapy with risankizumab for moderate-to-severe plaque psoriasis. Baseline characteristics included ...
Tópico(s): Autoimmune Bullous Skin Diseases
2021 - Adis, Springer Healthcare | Dermatology and Therapy
Martina Kojanová, Jorga Fialová, Petra Cetkovská, Thomas Dolezal, Iva Lomicová, Petr Arenberger, Spyridon Gkalpakiotis,
BIOREP is a Czech registry of patients with psoriasis undergoing biological treatment. The objective of the study was to compare differences in demographic data, previous therapy, comorbidities, severity of psoriasis, quality of life, drug survival rates, and reasons for discontinuation between men and women. We analyzed a cohort of patients from the registry treated between May 2005 and January 2020. The total study population of 2472 patients (4051 treatment series) included 913 females and 1559 ...
Tópico(s): Complementary and Alternative Medicine Studies
2021 - Wiley | Dermatologic Therapy

Astrid M. van Huizen, S.P. Menting, Rolland Gyulai, Lars Iversen, G. E. van der Kraaij, Maritza A. Middelkamp‐Hup, Richard B. Warren, Phyllis I. Spuls, Adrián A. Schejtman, Alexander Egeberg, Alireza Firooz, Alur S. Kumar, Amanda Oakley, Amy C. Foulkes, Andréa Machado Coelho Ramos, Anne‐Claire Fougerousse, Antoanela Čarija, Ayşe Akman-Karakaş, Barbara Horváth, Béata Fábos, Benjamín Hidalgo Matlock, Birgitta Wilson Claréus, Carla Castro, Carlos Ferrándiz, Carolina Cortés Correa, Carolina Marchesi, C. Goujon, Cèsar Gonzàlez, César Maldonado-García, Chih-ho Hong, C.E.M. Griffiths, Christian Vestergaard, Christina Mariela Echeverría, Claudia de la Cruz, Curdin Conrad, Dániel Törőcsik, Daniela Ledić Drvar, Deepak Balak, D. Jullien, Diebrecht Appelen, Dong Hyun Kim, E.M.G.J. de Jong, Emad El Gamal, Emmanuel Laffitte, E. Mahé, Enikö Sonkoly, Erika Páez Colombo, Eva Vilarrasa, Fabienne Willaert, Farah Novoa, Farhad Handjani, Fernando Valenzuela, Francisco Vílchez‐Márquez, Gabriela Otero González, Krisztián Gáspár, Giovanni Damiani, Gordana Krnjević-Pezić, Graciela Pellerano, G. Carretero, H.J.A. Hunter, Hassan Riad, Hazel H. Oon, Hugo P.J. Boonen, Iftin Osman Moussa, I. García‐Doval, Ildíko Csányi, Ines Brajac, Irina Turchin, Ivan Grozdev, Jeffrey M Weinberg, Jenny Nicolopoulos, Jillian Wells, Jo Lambert, J.R. Ingram, Jörg C. Prinz, José Alexandre de Souza Sittart, José Luis Alfonso Sánchez, Josephine Pa-Fan Hsiao, Juan Raúl Castro-Ayarza, Julia‐Tatjana Maul, J.M.P.A. van den Reek, Katarina Trčko, Kirk Barber, Kristian Reich, Kurt Gebauer, Kuzma Кhobzei, Lara Valeska Maul, Larisa Prpić Massari, L. Fardet, Laurence Le Cleach, L. Misery, Laxmisha Chandrashekar, Lidia Irinel Muresanu, L.L.A. Lecluse, Lone Skov, Ma. Lorna F. Frez, Lucija Tomić Babić, L. Puig, Luis Castro Gomez, M Ramam, Maha Dutil, Mahira Hamdy El-Sayed, Małgorzata Olszewska, M.E. Schram, Manuel Darío Franco Franco, Mar Llamas‐Velasco, Margarida Gonçalo, Margarita María Velásquez‐Lopera, María Eugenia Abad, Maria de Fátima Santos Paim de Oliveira, Marieke M.B. Seyger, Marija Kaštelan, Marius Rademaker, Mariusz Sikora, Mark Lebwohl, Marni Wiseman, Marta Ferrán, Martijn B. A. van Doorn, Maryam Danespazhooh, Matilda Bylaitė-Bučinskienė, Melinda Gooderham, Melita Vukšić Polić, Menno A. de Rie, Min Zheng, Minerva Gómez‐Flores, Montse Salleras Redonnet, Nanette B. Silverberg, N. Doss, Nikhil Yawalkar, O. Chosidow, Omid Zargari, P. de la Cueva, Pablo Fernández‐Peñas, Paola J. Cárdenas Rojas, Paolo Gisondi, Parbeer Grewal, Paul Sator, Paula Carolina Luna, Paulo Antonio Oldani Félix, Paulo Varela, Péter Holló, Petra Cetkovska, Piergiacomo Calzavara‐Pinton, Pierre‐Dominique Ghislain, Raquel Ruiz Araujo, Ricardo Romiti, Róbert Kui, Romana Čeović, Ronald Vender, R.F. Lafuente-Urrez, Rubén del-Río, Sandra Jerković Gulin, Sanjeev Handa, Satveer K. Mahil, Seetharam Anjaneyulu Kolalapudi, S.E. Marrón, Seyyede Zeinab Azimi, Sherief R. Janmohamed, Sidney Augusto da Cruz Costa, Siew Eng Choon, Slavomír Urbanček, Olusola Ayanlowo, Susana M. Margasin, Tak‐Wah Wong, Tarja Mälkönen, Tatiana Hurtová, Tatiana Riveros Reciné, Theis Huldt-Nystrøm, Tiago Torres, Tongyun Liu, Tsira Leonidze, Vinod Kumar Sharma, Warren Weightman, Wayne Gulliver, Wendelien Veldkamp,
Importance A clear dosing regimen for methotrexate in psoriasis is lacking, and this might lead to a suboptimal treatment. Because methotrexate is affordable and globally available, a uniform dosing regimen could potentially optimize the treatment of patients with psoriasis worldwide. Objective To reach international consensus among psoriasis experts on a uniform dosing regimen for treatment with methotrexate in adult and pediatric patients with psoriasis and identify potential future research topics. ...
Tópico(s): Pharmaceutical studies and practices
2022 - American Medical Association | JAMA Dermatology
Martina Kojanová, Jan Hugo, Barbora Velacková, Petra Cetkovská, Jorga Fialová, Tomáš Doležal, M Tichý, Spyridon Gkalpakiotis,
Real-world data on the use of interleukin-17 (IL-17) inhibitors for the treatment of psoriasis are limited.To evaluate and compare the efficacy, safety, and drug survival of IL-17 inhibitors.This retrospective study analyzed the BIOREP registry data of patients treated with at least one IL-17 inhibitor (secukinumab, ixekizumab, and brodalumab).In total, 949 patients were included. The improvement in PASI score was significant for all drugs, and the proportion of patients achieving PASI 75, 90, and ...
Tópico(s): Autoimmune Bullous Skin Diseases
2022 - Informa | Journal of Dermatological Treatment
Petra Brodská, Petr Panzner, Dalibor Sedláček, Milan Teřl, Petra Cetkovská,
Dupilumab is a monoclonal antibody against interleukin 4 (IL-4) receptor α that blocks signaling from IL-4 and IL-13, essential mediators of T helper 2 (Th2) pathway. To date, all clinical trials investigating the use of dupilumab excluded patients with human immunodeficiency virus. Herein, we describe the safe and successful use of dupilumab in a patient with atopic dermatitis, severe therapy resistant asthma, and HIV infection.
Tópico(s): Urticaria and Related Conditions
2020 - Wiley | Dermatologic Therapy
Martina Kojanová, Milena Tanczosová, Daniela Štrosová, Petra Cetkovská, Jorga Fialová, Tomáš Doležal, Alena Machovcová, Spyridon Gkalpakiotis,
Dupilumab has been approved to treat moderate-to-severe atopic dermatitis; however, the data in a real-world setting are still limited.To analyze the effectiveness and safety of dupilumab.This was a real-life Czech multicenter retrospective study from patients treated with dupilumab for severe AD.A total of 360 patients were included. At 16 weeks, 66.6, 34.1, and 5.5% of patients achieved EASI75/90 and EASI100, respectively. Improvement continued with the time, and the proportion of patients with ...
Tópico(s): Asthma and respiratory diseases
2022 - Informa | Journal of Dermatological Treatment
British Journal of DermatologyVolume 184, Issue 5 p. e148-e148 Correspondence: image gallery Successful treatment of refractory extensive pityriasis rubra pilaris with risankizumab J. Ricar, Corresponding Author ricarj@fnplzen.cz orcid.org/0000-0003-2079-236X Department of Dermatovenereology, Faculty of Medicine in Pilsen, Charles University, Prague, Czech Republic Contribution: Conceptualization (lead), Data curation (equal), Investigation (lead), Methodology (lead), Project administration (lead), Visualization ( ...
Tópico(s): Cutaneous lymphoproliferative disorders research
2020 - Oxford University Press | British Journal of Dermatology

Carla Ferrándiz‐Pulido, Álvaro Gómez‐Tomás, B. Llombart, D. López Mendoza, Joaquim Marcoval, Stefano Piaserico, Can Baykal, Jan Nico Bouwes-Bavinck, Emöke Rácz, Jean Kanitakis, Catherine Α. Harwood, Petra Cetkovská, Alexandra Geusau, V. del Mármol, Emili Masferrer, Carmen Orte Cano, Jan Říčař, Walmar Roncalli de Oliveira, Rafael Salido‐Vallejo, E. Ducroux, M.A. Gkini, José Antonio López‐Guerrero, Heinz Kutzner, Werner Kempf, Deniz Seçkin,
Abstract Background The proportion of Merkel cell carcinomas (MCCs) in solid‐organ transplant recipients (SOTR) harbouring Merkel cell polyomavirus (MCPyV) is unknown, as are factors affecting their outcomes. Objective To describe clinicopathological features of MCC in SOTR, investigate the tumoral MCPyV‐status and identify factors associated with tumour outcomes. Methods Retrospective, international, cohort‐study. MCPyV‐status was investigated by immunohistochemistry and polymerase chain reaction. ...
Tópico(s): Antenna Design and Analysis
2022 - Wiley | Journal of the European Academy of Dermatology and Venereology
Martina Kojanová, Petra Cetkovská, Daniela Štrosová, Jorga Fialová, Petr Arenberger, Tomáš Doležal, Spyridon Gkalpakiotis,
The study aimed to evaluate the real-world effectiveness of adalimumab as well as investigate the persistence of treatment and identify factors, which may affect it. More than 1150 patients (4363.1 patient-years) with psoriasis who had been treated with adalimumab since the start of the BIOREP registry in the Czech Republic were included in this analysis. Treatment effectiveness was defined as improvement in Psoriasis Area and Severity Index (PASI). The analysis was performed during the years 2005 ...
Tópico(s): Complementary and Alternative Medicine Studies
2021 - Adis, Springer Healthcare | Dermatology and Therapy
Iva Lomicová, D. Suchý, Karel Pizinger, Petra Cetkovská,
What is known and objective Drug-induced lupus erythematosus occurs with some drugs and resolves with their withdrawal. Anti-TNF therapies have been found to be associated with a lupus-like syndrome, which is clinically distinct from classical drug-induced as well as idiopathic lupus erythematosus. Case description We describe a case of a patient with severe psoriasis, who developed muscle pain with paraesthesia accompanied by ANA titres elevation with adalimumab treatment. The condition resolved ...
Tópico(s): Inflammatory Bowel Disease
2017 - Wiley | Journal of Clinical Pharmacy and Therapeutics
Jan Hugo, Martina Kojanová, Barbora Turková, Spyridon Gkalpakiotis, Zdenek Antal, Petr Arenberger, Jirina Bartonová, Linda Blahova, Petra Brodská, P. Boháč, Hana Bučková, Martin Cetkovsky, Petra Cetkovská, Jana Cadova, Dominika Diamantova, Magdalena Dobiasova, Hana Duchkova, Jorga Fialová, Olga Filipovska, Jana Földesová, Petra Gkalpakioti, Martina Grycova, Jiří Horažďovský, Eva Horka, Katerina Hrazdirova, Eduard Hrncir, Jana Chlebková, Jaromira Janku, Lucie Růžičková Jarešová, Renáta Kopová, Dora Kovandova, Silvie Krchova, Lenka Kulmanova, Natalie Kunesova, Iva Lomicová, Romana Machackova, Alena Machovcová, Hana Malíková, Martina Matzenauer, Miroslav Nečas, Helena Němcová, Radka Neumannova, Michaela Nováková, Jitka Osmerova, Veronika Pallova, Lucie Petru, Blanka Pinková, Zuzana Plzáková, Marie Policarová, Tomáš Pospíšil, Filip Rob, M Salavec, Marie Selerová, Veronika Slonková, Jiri Strok, Ivana Strouhalova, David Stuchlik, Alena Stumpfova, Jaroslav Ševčík, Jan Šternberský, Kateřina Švarcová, Katerina Tepla, M Tichý, H Tomková, Yvetta Vantuchová, Ivana Vejrova, Iva Zampachova,
Real-world data on the long-term use of guselkumab for treatment of psoriasis are still limited. We aimed to evaluate long-term efficacy, safety, and drug survival of guselkumab in a real-world setting. This is a retrospective study analyzing Czech Republic registry (BIOREP) data of patients treated with guselkumab. In total, 333 patients were included. Improvement in Psoriasis Area and Severity Index (PASI) score was significant. Mean PASI score decreased from 16 at baseline to 0.7, 0.9, and 0.8 ...
Tópico(s): Pharmaceutical studies and practices
2023 - Adis, Springer Healthcare | Dermatology and Therapy
Petra Cetkovská, Karel Pizinger, Alena Skálová,
A case of a bullous eruption occurred in a patient being treated with penicillamine for sclerodermatous graft-versus-host disease following bone marrow transplantation. After 7 days of treatment with 150 mg penicillamine, a painful bullous eruption with accompanying purpuric lesions suddenly developed in previous sclerodermatous infiltrations. A diagnosis of epidermolysis bullosa acquisita–like eruption was made, and the patient was treated with drug withdrawal and administration of cyclosporine ...
Tópico(s): Autoimmune Bullous Skin Diseases
2003 - Elsevier BV | Journal of the American Academy of Dermatology
Choon Chiat Oh, Günther F.L. Hofbauer, Andreas L. Serra, Catherine Α. Harwood, L. Mitchell, Charlotte M. Proby, Edit Olasz, Daniel D. Mosel, Stefano Piaserico, Anna Belloni Fortina, Alexandra Geusau, Karin Jahn‐Bassler, M. Gerritsen, Deniz Seçkin, A. Tülin Güleç, Petra Cetkovská, Jan Říčař, Beata Imko‐Walczuk, Alicja Dębska‐Ślizień, Jan Nico Bouwes Bavinck,
Organ transplant recipients (OTRs) have a highly increased risk of cutaneous squamous cell carcinomas (SCCs). Sensation of pain in cutaneous tumours is a powerful patient‐reported warning signal for invasive SCCs in OTRs. To investigate the impact of painful vs. painless skin lesions and SCC vs. other skin lesions on the overall mortality risk in OTRs. We followed 410 OTRs from 10 different centres across Europe and North America between 2008 and 2015. These patients had been enrolled in an earlier ...
Tópico(s): Wound Healing and Treatments
2016 - Oxford University Press | British Journal of Dermatology
M Tichý, Martina Kojanová, Barbora Velacková, Tomáš Doležal, Spyridon Gkalpakiotis, Petra Cetkovska,
The IL-17 cytokine family encompasses six different homodimers and heterodimers referred to as IL-17A-F. Due to some differences in the mechanism of IL-17 inhibition, aninsufficient effect of one IL-17 inhibitor does not necessarily imply lack of efficacy of the other agent of the same class. Aim of study was analysis of the success rate of switches among IL-17 inhibitors (secukinumab, ixekizumab, and brodalumab) in patients treated in the Czech Republic. Data were obtained from the Czech nationwide ...
Tópico(s): Spondyloarthritis Studies and Treatments
2022 - Wiley | Dermatologic Therapy
Lajos Kemény, M. Amaya, Petra Cetkovská, Natta Rajatanavin, W. R. Lee, Annette Szumski, Lisa Marshall, Ehab Mahgoub, Emre Aldinc,
Psoriasis prevalence and characteristics in Asia, Central Europe, and Latin America have not been thoroughly investigated and there are no large trials for biologic treatments for patients from these regions. The goal of this analysis was to report clinical response to anti-tumor necrosis factor-alpha treatment in these patients.Patients from Argentina, Czech Republic, Hungary, Mexico, Taiwan, and Thailand (N=171) were included in this subset analysis of the PRISTINE trial. Patients with stable moderate- ...
Tópico(s): Asthma and respiratory diseases
2015 - Springer Science+Business Media | BMC Dermatology
Petra Cetkovská, Iva Dediol, Marija Šola, Martina Kojanová, Katarina Trčko, Antoanela Čarija, Romana Čeović, Daniela Ledić-Drvar, Marija Kaštelan, Andina Hrabar, Myriam Cordey Missoup, Khalid Mamun,
The broad and sustained efficacy of apremilast for psoriasis has been demonstrated in randomized and real-world observational studies. Data from Central and Eastern Europe (CEE) are lacking. Moreover, apremilast use in this region is limited by country-specific reimbursement criteria. This is the first study to report data on the real-world use of apremilast in the region.APPRECIATE (NCT02740218) was an observational, retrospective, cross-sectional study assessing psoriasis patients 6 (± 1) months after ...
Tópico(s): Complementary and Alternative Medicine Studies
2023 - Adis, Springer Healthcare | Advances in Therapy