Mike English, Stephen Ntoburi, John Wagai, Patrick Mbindyo, Newton Opiyo, Philip Ayieko, Charles Opondo, Santau Migiro, Annah Wamae, Grace Irimu,
It is increasingly appreciated that the interpretation of health systems research studies is greatly facilitated by detailed descriptions of study context and the process of intervention. We have undertaken an 18-month hospital-based intervention study in Kenya aiming to improve care for admitted children and newborn infants. Here we describe the baseline characteristics of the eight hospitals as environments receiving the intervention, as well as the general and local health system context and ...
Tópico(s): Child Nutrition and Water Access
2009 - BioMed Central | Implementation Science
Grace Irimu, Annah Wamae, A. Wasunna, FN Were, Stephen Ntoburi, Newton Opiyo, Philip Ayieko, Norbert Peshu, Mike English,
The under-5 mortality rate in most developing countries remains high yet many deaths could be averted if available knowledge was put into practice. For seriously ill children in hospital investigations in low-income countries commonly demonstrate incorrect diagnosis and treatment and frequent prescribing errors. To help improve hospital management of the major causes of inpatient childhood mortality we developed simple clinical guidelines for use in Kenya, a low-income setting. The participatory ...
Tópico(s): Global Maternal and Child Health
2008 - BMJ | Archives of Disease in Childhood
Yaw Bediako, Joyce Ngoi, George Nyangweso, Juliana Wambua, Michael Opiyo, Eunice Nduati, Philip Bejon, Kevin Marsh, Francis M. Ndungu,
Naturally acquired immunity to malaria may be lost with lack of exposure. Recent heterogeneous reductions in transmission in parts of Africa mean that large populations of previously protected people may lose their immunity while remaining at risk of infection.Using two ethnically similar long-term cohorts of children with historically similar levels of exposure to Plasmodium falciparum who now experience very different levels of exposure, we assessed the effect of decreased parasite exposure on ...
Tópico(s): Mosquito-borne diseases and control
2016 - BioMed Central | BMC Medicine
Sylvia A. Opiyo, Lawrence Onyango Arot Manguro, Philip Okinda-Owuor, Elijah Ateka, Peter Lemmen,
7α-Acetylugandensolide together with thirteen known drimane-type sesquiterpenes have been isolated from Warbugia ugandensis bark extracts. Their structures were established by spectroscopic and physical methods as well as comparison with data available in the literature. The in vitro antimicrobial activities of the extracts and isolates were investigated against fungi and bacteria which infect sweet potato. Ethyl acetate extract exhibited the highest (P ≤ 0.05) antifungal and antibacterial activities ...
Tópico(s): Bioactive Compounds and Antitumor Agents
2011 - Elsevier BV | Phytochemistry Letters
David Gathara, Newton Opiyo, John Wagai, Stephen Ntoburi, Philip Ayieko, Charles Opondo, Annah Wamae, Santau Migiro, Wycliffe Mogoa, Aggrey Wasunna, Fred Were, Grace Irimu, Mike English,
Given the high mortality associated with neonatal illnesses and severe malnutrition and the development of packages of interventions that provide similar challenges for service delivery mechanisms we set out to explore how well such services are provided in Kenya. As a sub-component of a larger study we evaluated care during surveys conducted in 8 rural district hospitals using convenience samples of case records. After baseline hospitals received either a full multifaceted intervention (intervention ...
Tópico(s): Global Health and Epidemiology
2011 - BioMed Central | BMC Health Services Research
Romanus Opiyo, Philip Osano, Aderiana Mbandi, William Apondo, Cassilde Muhoza,
Tópico(s): Wildlife-Road Interactions and Conservation
2020 - National Association for Clean Air | Clean Air Journal
Peter Odhengo, Alphayo Lutta, Philip Osano, Romanus Opiyo,
Tópico(s): Urban Agriculture and Sustainability
2024 - Elsevier BV | Cities
Charles Opondo, Philip Ayieko, Stephen Ntoburi, John Wagai, Newton Opiyo, Grace Irimu, Elizabeth Allen, James R. Carpenter, Mike English,
There are few reports of interventions to reduce the common but irrational use of antibiotics for acute non-bloody diarrhoea amongst hospitalised children in low-income settings. We undertook a secondary analysis of data from an intervention comprising training of health workers, facilitation, supervision and face-to-face feedback, to assess whether it reduced inappropriate use of antibiotics in children with non-bloody diarrhoea and no co-morbidities requiring antibiotics, compared to a partial ...
Tópico(s): Global Maternal and Child Health
2011 - BioMed Central | BMC Pediatrics
Trevor Duke, Harry Campbell, Philip Ayieko, Newton Opiyo, Mike English, Julian Kelly, Susanne Carai, Giorgio Tamburlini, Martin Weber,
WHO regularly gathers, evaluates, and cites evidence to support its recommendations. How this is done varies between departments, but highly centralized processes, complex methods and expert consultations are often used. WHO guidelines are distributed to health workers and policy-makers in developing countries, but few of these people have the opportunity to be involved in the process of choosing and weighing the evidence to formulate the guidelines that are ostensibly designed for their use. Such ...
Tópico(s): Global Health and Surgery
2006 - World Health Organization | Bulletin of the World Health Organization
Philip Ayieko, Stephen Ntoburi, John Wagai, Charles Opondo, Newton Opiyo, Santau Migiro, Annah Wamae, Wycliffe Mogoa, Fred Were, Aggrey Wasunna, Greg Fegan, Grace Irimu, Mike English,
In developing countries referral of severely ill children from primary care to district hospitals is common, but hospital care is often of poor quality. However, strategies to change multiple paediatric care practices in rural hospitals have rarely been evaluated.This cluster randomized trial was conducted in eight rural Kenyan district hospitals, four of which were randomly assigned to a full intervention aimed at improving quality of clinical care (evidence-based guidelines, training, job aides, ...
Tópico(s): Primary Care and Health Outcomes
2011 - Public Library of Science | PLoS Medicine
Francis Edward Omondi Opiyo, Moses Nyangito, Oliver Vivian Wasonga, Philip Omondi,
Tópico(s): Rangeland Management and Livestock Ecology
2014 - | Environmental Research Journal
Alexandra Torborg, Heidi M. Meyer, Mahmoud El Fiky, Maher Fawzy, Muhammed Elhadi, Adesoji Ademuyiwa, Babatunde Osinaike, Adam Hewitt‐Smith, Mary T. Nabukenya, Ronald Bisegerwa, Souad Bouaoud, Meriem Abdoun, Ahmed Rhassane El Adib, Fitsum Kifle, Meseret Gebre, Desalegn Bekele Taye, Nahla Kechiche, Tarig Fadalla, Bassel Abdallah, Maman Sani Chaibou, Mame Yaa Nyarko, Kélan Bertille Ki, Sarah Shalongo, Wakisa Mulwafu, Emma C. Thomson, M Traoré, Andrew Ndonga, Mustapha Bittaye, Ahmadou Lamin Samateh, Dolly M. Munlemvo, Jean Jacques Kalongo, Yacaria Coulibaly, Coulibaly Youssouf, Vaonandianina Ravelojaona, Lalatiana M. Andriamanarivo, Arsitide Romain Raherison, Harifetra Mamy Richard Randriamizao, Kushal Ramkalawan, Mohamed Omar, Raymond Ndikontar, Joseph Donamou, Shukri Dahir, Mubarak Mohamed, Hassan Ali Daoud, Pisirai Ndarukwa, Gilbert Fabrice Otiobanda, Paulin Banguti, Kara Neil, Miliard Derbew, Marvin Fanny, Isaac Smalle, Elliott H Taylor, Hanel Duvenage, Anneli Hardy, Hyla‐Louise Kluyts, Rupert M. Pearse, Bruce Biccard, Olurotimi Aaron, Hossam Aldein Samir Abd Elazeem Mohammed, Batool Abdalkarim, Abubaker Abdalla, Mohamed Abubaker Ahmed Abdallah, Saedah Abdeewi, Taqwa Abdel Ghafar, Ali Abdelaleem, Ibrahim Abdelmonaem Abdelaleem, Khansaa Abdelgader, Waffa Abdelgadir, Mohammed Abdelhafez, Ahmed Abdelhalim, Mohammed Abdelkabir, M.A. Osman, Maha Abdelkarim, Mohamed Abdelkarim, Sarah Magdy Abdelmohsen, Mazin Abdelnassir, A Abdelrahman, Aya Elsayed Abdelwahed, M. A. Abdelzaher, Baba Ahmed Abderrahim, Abdoulaye Touré, Samira Abdulai, Yunus A. Abdulghaffar, Fatimaalzahraa Abdullah, Lawal Abdullahi, Muzammil Abdullahi, Sarah Abdulrazik, Khalifa Ibrahim Abdulsalam, Eman Abdulwahed, Rukiyat A Abdus-Salam, TOLUSHE ABE, Gersam Abera Mulugeta, Aml Ali Aboelghait, Nariman Abol Oyoun, Boumediene Aboubekr, M Abraham, Mohammed Ardo Abu, Ahlam ali Abuagila, Maimuna Abubakar, Mohammed Abugilah, Issa A. Abuzeid, Djelloul Achouri, Serwah Akua Acquah, Nusiba Bushra Ahmed Adam, Auwal Adamu, Kabir Musa Adamu, Muhammad Shuaibu Adamu, Sani Adamu, Samuel Gashu Adane, Mojolaoluwa Adeaga, Sikiru Adebayo, Adejare Adedire, Paul Aderemi Adegoke, Adesoji Ademuyiwa, Adebayo Augustine Adeniyi, Ibukunoluwa Adeoye, Gbenga A Aderibigbe, Azeezat B. Aderounmu, WILLIAMS ADEYEMI, Adekunle Adeyemo, Tinuola Adigun, Enoch Delad Adika, Adewale Adisa, Esther M Adjei, Ernest Kwame Adjepong-Tandoh, Alaa Mohamed Ads, Dr Collins Chijioke ADUMAH, Lilian ogechi ADUMAH, Innocent Adzamli, J. Afari, Wisdom Afedo, Abubaker Affan, Ayodeji Olawale Afolayan, S Agaba, Evans Kofi Agbeno, Peter Agbonrofo, Ifeanyi Kene Aghadi, Edith Agu, Thomas Agyen, Kwasi Agyen‐Mensah, Daasebre Ahensan, Misbahu Haruna Ahmad, Awrayit AHMED, Linda Ahmed, Nidal Youseef Altaher Aboh Ahmed, Rubaa Ahmed, Mohamed Ahmed Jroush, Hasan ahmed maghur, G.N. Geofroid AHOGNI, Smain Ait Yahia, Narjiss Aji, Sani Aji, William Akerele, Irene Akhideno, Israel Akinmokun, Akin Taofeek AKINNIYI, Ayodeji Akinniyi, Samuel AKINYEMI, Olumide Adeleke Akitoye, Iniofon Clement Akpaette, Terungwa Jacob Akuma, Daniel Akuokor, Clement Nii-Akwei Akwei, Rayan Badran Hamed Al Bashir, Mohamed Fathi Al Gharyani, Rayet al Islam ben Jouira, Timothy Aladelusi, Felix Alakaloko, Hind Alameen, Mohammed Alameen Moheyaldeen, Mona Alaogaly, Rehab Alarabi, Milud Alawami, Basma Masaud Alazabi, Mona Alazabi, Bashir Abobaker Albakosh, HUSAYN MOHAMMED ElFEETOURI ALBDULRRAZIQ, Asmma Aldieb, Wafa Aldressi, Godwin E. Alegbeleye, Yakubu Alfa, Qamrah Alhadad, Arwa R Alhaddad, Hayfa Faraj Alhaddad, Aliya Alhadi, Aya Alhamali, Abtisam Alharam, Majduldeen Alhlafi, Basmah Alhouwasi, Sara Alhudhairy, A Ali, Ahmed Jama Ali, Almuaz Ali, Asma Ali, Enas M. Ali, M. Aamir Ali, Ali Salem, Yunusa Y. Ali, Abdelbaset Ali Ahmed, Sampson Aliozor, Sarah Aljamal, Akram Alkaseek, Elmustafa Alkhalifa, Samah Alkoni, Abbaas Allie, Khawla Almelyan, Ayman Almugaddami, Asmaa Almujreesi, Eithar Alqady, Alaa Ahmed Alragheai, Entisar Alshareea, Abulnasir Alshareef, Mohamed Alsori, Seham Ahmed Altomy, Aiman Al-Touny, Shimaa A. Al-Touny, Rachel Alum Aguma, Nuha Miftah Alwaer, Hadeel Al-zletni, Marwa Alzwai, Nelago Amaambo, Christopher Amah, Marwa Amary, Ludovic Albert Amengle, Shiwana Lineekela Omwene Amesho, Mawuli Ametepe, Emad Amkhatirah, Mohamed Gamal Amnaina, Benjamin Amoah, Joseph Kofi Amoah, Nana Adjoa Simitsewa Amo-Aidoo, Mabel Pokuah Amoako-Boateng, Jude Ampong, Betty Anane-Fenin, S Anarfi, Mamy Lalatiana Andriamanarivo, Luke Adagrah Aniakwo, Ernest Aniteye, Levi Ankrah, Audrey Anno, Lofty‐John Anyanwu, Edem Anyigba, William Appeadu‐Mensah, Peter Appiah–Thompson, Ewuarabena Lydia Apraku-Peprah, Shuaib Kayode Aremu, Moses Arinaitwe, Ralph Armah, Augustine Arthur, Douglas W. Arthur, Kwaku Asah‐Opoku, Mabel Asante, Alvin Asante-Asamani, Angbo Asare, Lausa Asasira, Mohamed Ashfersh, John Adi Ashindoitiang, Joycelyn Ashong, Mohamed A. Salah, Charles Asiedu, Isaac Asiedu, Kolawole Asiyanbi, Amir Asla, Wilfred K Asman, Emeka J. Asoegwu, Mohamed Assalhi, Claudia Assim, Felicia Dele Asudo, Alice Gertrude Atai, Sara Bin Ateeqa, Terkaa Atim, Solomon Atindama, IJLAL ATIQUI, Zoubir Atrih, Raphael Avidime Attah, Ahmed K. Awad, Atalel Fentahun Awedew, Atalel Fentahun Awedew, Husayn Aween, Lawrence K. B. Awere-Kyere, Joseph K Awindaogo, Margaret Awori Achani, Kusay Ayad, Ahmed Azab, Alberta Azas, Bochra Aziza, Diallo Abdoul Azize, Abdelkrim AZOUI, Jomana Sami Azouz, Suleiman Baba, Olakunle Fatai Babalola, M.O.E. Babiker, Daniel Baddoo, Aml Badi, S A Badmus, Helmy Badr,
Summary Background Safe anaesthesia and surgery are a public health imperative. There are few data describing outcomes for children undergoing anaesthesia and surgery in Africa. We aimed to get robust epidemiological data to describe patient care and outcomes for children undergoing anaesthesia and surgery in hospitals in Africa. Methods This study was a 14-day, international, prospective, observational cohort study of children (aged <18 years) undergoing surgery in Africa. We recruited as many hospitals ...
Elsevier BV
Horace Gumba, Michael Opiyo, Jennifer Musyoki, Martin Mutunga, Caroline Ngetsa, Salim Mwarumba, Moses Mosobo, Susan Njuguna, Oscar Kai, Arnold W. Lambisia, Domtila Kimani, Robinson Cheruiyot, Patience Kiyuka, Clement Lewa, Elijah Gicheru, Metrine Tendwa, Khadija Said Mohammed, Victor Osoti, Johnstone Makale, Brian Tawa, Calleb Odundo, Wesley Cheruiyot, Wilfred Nyamu, Wilson Gumbi, Jedidah Mwacharo, Lydia Nyamako, Edward Otieno, David Amadi, Nelson Ouma, Boniface Karia, Janet Thoya, Angela Karani, Daisy Mugo, Bonface M. Gichuki, Debra Riako, Shadrack Mutua, John N. Gitonga, Kelly Ominde, Perpetual Wanjiku, Agnes Mutiso, Alfred Mwanzu, Yiakon Sein, Brian Bartilol, Shaban Mwangi, Donwilliams O. Omuoyo, John Mwita Morobe, Zaydah R. de Laurent, Fredrick Mitsanze, Alfred Mwakubia, Martin Rono, Amek Nyaguara, Benjamin Tsofa, Philip Bejon, Charles N. Agoti, Lynette Isabella Ochola‐Oyier,
Laboratory diagnosis plays a critical role in the containment of a pandemic. Strong laboratory quality management systems (QMS) are essential for laboratory diagnostic services. However, low laboratory capacities in resource-limited countries has made the maintenance of laboratory quality assurance, especially during a pandemic, a daunting task. In this paper, we describe our experience of how we went about providing diagnostic testing services for SARS-CoV-2 through laboratory reorganization, redefining of ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2021 - Wellcome | Wellcome Open Research
Horace Gumba, Michael Opiyo, Jennifer Musyoki, Martin Mutunga, Caroline Ngetsa, Salim Mwarumba, Moses Mosobo, Susan Njuguna, Oscar Kai, Arnold W. Lambisia, Domtila Kimani, Robinson Cheruiyot, Patience Kiyuka, Clement Lewa, Elijah Gicheru, Metrine Tendwa, Khadija Said Mohammed, Victor Osoti, Johnstone Makale, Brian Tawa, Calleb Odundo, Wesley Cheruiyot, Wilfred Nyamu, Wilson Gumbi, Jedidah Mwacharo, Lydia Nyamako, Edward Otieno, David Amadi, Nelson Ouma, Boniface Karia, Janet Thoya, Angela Karani, Daisy Mugo, Bonface M. Gichuki, Debra Riako, Shadrack Mutua, John N. Gitonga, Kelly Ominde, Perpetual Wanjiku, Agnes Mutiso, Alfred Mwanzu, Yiakon Sein, Brian Bartilol, Shaban Mwangi, Donwilliams O. Omuoyo, John Mwita Morobe, Zaydah R. de Laurent, Fredrick Mitsanze, Alfred Mwakubia, Martin Rono, Amek Nyaguara, Benjamin Tsofa, Philip Bejon, Charles N. Agoti, Lynette Isabella Ochola‐Oyier,
Laboratory diagnosis plays a critical role in the containment of a pandemic. Strong laboratory quality management systems (QMS) are essential for laboratory diagnostic services. However, low laboratory capacities in resource-limited countries has made the maintenance of laboratory quality assurance, especially during a pandemic, a daunting task. In this paper, we describe our experience of how we went about providing diagnostic testing services for SARS-CoV-2 through laboratory reorganization, redefining of ...
Tópico(s): COVID-19 diagnosis using AI
2022 - Wellcome | Wellcome Open Research