Ellen F. Heineman, Pierluigi Cocco, Manuel R. Gómez, Mustafa Dosemeci, Patricia A. Stewart, Richard B. Hayes, Shelia Hoar Zahm, Tami L. Thomas, Aaron Blair,
Abstract Chlorinated aliphatic hydrocarbons (CAHs) were evaluated as potential risk factors for astrocytic brain tumors. Job‐exposure matrices for six individual CAHs and for the general class of organic solvents were applied to data from a case‐control study of brain cancer among white men. The matrices indicated whether the CAHs were likely to have been used in each industry and occupation by decade (1920‐1980), and provided estimates of probability and intensity of exposure for “exposed” industries ...
Tópico(s): Air Quality and Health Impacts
1994 - Wiley | American Journal of Industrial Medicine
Elisa Gentilotti, Anna Górska, Adriana Tami, Roy Gusinow, Massimo Mirandola, Jesús Rodríguez‐Baño, Zaira R. Palacios‐Baena, Elisa Rossi, Jan Hasenauer, Iris Lopes-Rafegas, Elda Righi, Natascia Caroccia, Salvatore Cataudella, Zeno Pasquini, Thomas Osmo, Lidia Del Piccolo, Alessia Savoldi, Samir Kumar‐Singh, Fulvia Mazzaferri, Maria Giulia Caponcello, Gerolf de Boer, Gabriel Levy Hara, Pasquale De Nardo, Surbhi Malhotra, Lorenzo Maria Canziani, Jade Ghosn, Aline-Marie Florence, Nadhem Lafhej, Bernardina T.F. van der Gun, Maddalena Giannella, Cédric Laouénan, Evelina Tacconelli, Mariana Guedes, Gaia Maccarrone, Maria Diletta Pezzani, Marcella Sibani, Ruth Joanna Davies, Stefania Vitali, Giorgia Franchina, Giorgia Tomassini, Concetta Sciammarella, Riccardo Cecchetto, Davide Gibellini, Chiara Konishi De Toffoli, Giulia Rosini, Chiara Perlini, Marco Meroi, Filippo Cioli Puviani, Daniele Fasan, Claudio Micheletto, Stefania Montemezzi, Nicolò Cardobi, Gianluca Vantini, Gloria Mazzali, Giovanni Stabile, Maddalena Marcanti, Marco Pattaro Zonta, D Calì, Anna Mason, Cinzia Perlini, Paolo Gisondi, Maria Mongardi, Simona Sorbello, Karin I. Wold, María F. Vincenti‐González, A.C.M. Veloo, Valerie P. R. Harmsma, Daniele Pantano, Margriet van der Meer, Lilli Gard, Erley Lizarazo, Marjolein Knoester, Alex W. Friedrich, Hubert G.M. Niesters, Pierluigi Viale, Domenico Marzolla, Federica Cosentino, Michela Di Chiara, Giacomo Fornaro, Cecilia Bonazzetti, Beatrice Tazza, Alice Toschi, Oana Vetamanu, Maria Eugenia Giacomini, Filippo Trapani, Lorenzo Marconi, Luciano Attard, Sara Tedeschi, Liliana Gabrielli, Tiziana Lazzarotto, Paula Olivares, Javier Castilla, J. Velez, Virginia Almadana Pacheco, Lucía Martín-Barrera, Ana Belén Martín-Gutiérrez, David Gutiérrez-Campos, Marta Fernández-Regaña, Ana Silva-Campos, Patricia Fernández‐Riejos, Maria-Isabel García-Sanchéz, Carla V. Giuliano, Carlota López, Gabriela Neumann, Julieta Camporro, Lautaro De Vedia, Hugo Agugliaro, Gabriella Scipione, Chiara Dellacasa, Balasubramanian Chandramouli, Silvia Gioiosa, Juan Mata Naranjo, M. Ortali, Angelina Konnova, Akshita Gupta, Mathias Smet, An Hotterbeekx, Matilda Berkell, Elisa Sicuri, Delphine Bachelet, Lila Bouadma, Minerva Cervantes-Gonzalez, Anissa Chair, Charlotte Charpentier, Léo Chenard, Diane Descamps, Hang Thi Doan, Xavier Duval, Marina Esposito‐Farèse, Isabelle Hoffmann, Ouifiya Kafif, Quentin Le Hingrat, Sophie Letrou, France Mentré, Marion Schneider, Coralie Tardivon, Jean‐François Timsit, Sarah Tubiana, Amal Abrous, Sandrine Couffin-Cadiergues, Fernanda Dias Da Silva, Hélène Esperou, Ikram Houas, Salma Jaafoura, Aurélie Papadopoulos, Séverine Ansart, Adrien Auvet, Firouzé Bani‐Sadr, Louis Bernard, François Bissuel, Élisabeth Botelho-Nevers, Damien Bouhour, André Cabie, Pauline Caraux Paz, Christian Chidiac, Catherine Chirouze, Tomasz Chroboczek, Hugues Cordel, Roxane Courtois, Nathalie De Castro, Sylvain Diamamntis, Jean-Luc Diehl, Félix Djossou, Céline Dorival, Olivier Épaulard, Valerie Gaborieau, François Goehringer, Marie Gousseff, Simon Jamard, Cédric Joseph, Karine Lacombe, Soizic Le Mestre, Vincent Le Moing, Jean‐Daniel Lelièvre, O. Lesens, Marina Machado, Mylène Maillet, Victoria Manda, Guillaume Martin‐Blondel, M. Martinot, Vanina Meysonnier, Jean‐Michel Molina, Eric Oziol, Vincent Pestre, Lionel Piroth, Julien Poissy, Christian Rabaud, François Raffi, Blandine Rammaert, Christophe Rapp, Stanislas Rebaudet, Pierre‐Marie Roger, Damien Roux, Eric Senneville, Pierre Tattevin, Aurélie Wiedemann, David Zucman,
Lack of specific definitions of clinical characteristics, disease severity, and risk and preventive factors of post-COVID-19 syndrome (PCS) severely impacts research and discovery of new preventive and therapeutics drugs.This prospective multicenter cohort study was conducted from February 2020 to June 2022 in 5 countries, enrolling SARS-CoV-2 out- and in-patients followed at 3-, 6-, and 12-month from diagnosis, with assessment of clinical and biochemical features, antibody (Ab) response, Variant ...
Tópico(s): COVID-19 and Mental Health
2023 - Elsevier BV | EClinicalMedicine
John Kuruvilla, John C. Byrd, Joseph M. Flynn, Ramiro Garzon, Pierluigi Porcu, Nina D. Wagner‐Johnston, Mary Lynn Savoie, Richard M. Stone, Eric D. Jacobsen, Morten Mau‐Sørensen, Peter de Nully Brown, Rachid Baz, Bijal Shal, Ian W. Flinn, Nashat Gabrail, Vishal Kukreti, Rodger E. Tiedemann, Yosef Landesman, Boris Klebanov, Eran Shacham, Jean‐Richard Saint‐Martin, Tracey Marshall, John S. McCartney, Dilara McCauley, Robert Carlson, Sasha Norori, Michael R. Savona, Tami Rashal, Mansoor Raza Mirza, Michael Kauffman, Sharon Shacham,
Abstract Background: The nuclear export protein, XPO1 is overexpressed in all types of malignant lymphoma. The SINE selinexor (KPT-330) is a slowly reversible XPO1 antagonist that forces the nuclear retention and activation of over 10 tumor suppressor proteins (TSP) such as p53, IkB, FOXO and p21. In addition, selinexor inhibits the nuclear export and the translation of oncogenic mRNAs such as c-myc and Bcl-XL levels. Together these effects result in apoptosis of cancer cells in preclinical models ...
Tópico(s): Nuclear Structure and Function
2014 - Elsevier BV | Blood
Erdal Çavuşoğlu, John Kassotis, Jonathan D. Marmur, Mary Ann, Roberta De Rosa, Salvatore De Rosa, David M. Leistner, Jes‐Niels Boeckel, Cian Mccarthy, Roland van Kimmenade, Hanna K. Gaggin, Mandy L. Simon, Nasrien E. Ibrahim, Parul U. Gandhi, Noreen Kelly, Shweta R. Motiwala, Arianna M. Belcher, Jamie Harisiades, Sebastiano Gili, David Fabrizio, Roberto Ascenzo, Federico Summa, Enrico Conrotto, Alaide Cerrato, Giacomo Chieffo, Antonio Boccuzzi, Fabrizio Montefusco, Pierluigi Ugo, ́ Omede, Hiroyoshi Kawamoto, Francesco Tomassini, Marco Pavani, Ferdinando Varbella, Roberto Garbo, Maurizio Amico, Giuseppe Biondi‐Zoccai, Claudio Moretti, Javier Escaned, Antonio Colombo, Fiorenzo Gaïta, Judit Karácsonyi, Dimitri Karmpaliotis, Khaldoon Alaswad, Farouc A. Jaffer, Robert W. Yeh, Mitul Patel, Ehtisham Mahmud, William Lombardi, Michael R. Wyman, Anthony Doing, Jeffrey W. Moses, Ajay J. Kirtane, Manish Parikh, Ziad A. Ali, David E. Kandzari, Nicholas Lembo, Santiago García, Barbara A. Danek, Aris Karatasakis, Erica Resendes, Pratik Kalsaria, Bavana Rangan, Imre Ungi, Craig R. Thompson, Subhash Banerjee, Emmanouil S. Brilakis, J. Yeoh, M. Yudi, Nick Andrianopoulos, Bryan P. Yan, David Clark, Stephen W. Duffy, Angela Brennan, Gishel New, Mélanie Freeman, D. Eccleston, M. Sebastian, Christopher Reid, Shoichi Kuramitsu, Hiroyuki Jinnouchi, Tomohiro Shinozaki, Takashi Hiromasa, Yukiko Matsumura, Yuhei Yamaji, Mizuki Miura, Hiroaki Matsuda, Hisaki Masuda, Takenori Domei, Rahman Shah, Mohamed Morsy, Darryl S. Weiman, George W. Vetrovec, Hun Kang, Whan Lee, Seunghee Baek, Hyung Lee, Jung‐Min Ahn, Duk‐Woo Park, Soo‐Jin Kang, Seung‐Whan Lee, Younghak Kim, Seong‐Wook Park, Seung‐Jung Park, Anjani Golive, Heidi T. May, Tami L. Bair, Victoria Jacobs, Brian G. Crandall, Michael J. Cutler, John Day, Charles Mallender, Jeffrey S. Osborn, Scott Stevens, J. Peter Weiss, Scott C. Woller, T. Jared Bunch, Christopher X. Hong, Krishna Alluri, Nasir Shariff, Furqan Khattak, Evan Adelstein, Josep Rode ́s-Cabau, Gilles O’Hara, Jean‐Michel Paradis, Mathieu Bernier, Tania Rodríguez‐Gabella, Ander Regueiro, Teresa Trenkwalder, Ryan P. King, Bernhard M. Kaess, Christian Hengstenberg, Heribert Schunkert, Stephan B. Felix, Mathias Busch, Marcus Do, Wibke Reinhard, Andrew P. Ambrosy, Ankeet S. Bhatt, Dianne Gallup, Kevin Anstrom, Javed Butler, Adam D. DeVore, G. Michael Felker, Marat Fudim, Stephen J. Greene, Adrian F. Hernandez, Jacob P. Kelly, Marc D. Samsky, Robert J. Mentz, Giuseppe Di Gioia, Roberto Scarsini, Teresa Strisciuglio, Chiara De Biase, Richa Gupta, Crystal Tichnell, Brittney Murray, Mitsunobu Kitamura, Yasuo Amano, Takayama Morimasa, Junsuke Shibuya, Junya Matsuda, Hideto Sangen, Shunichi Nakamura, Hitoshi Takano, Marica Baleilevuka-Hart, Trevor Feldman, Seshadri Balaji,
2017 - Elsevier BV | The American Journal of Cardiology