George E. Johnson, Frank P. Stafford,
... reports the following articles citing this article:Clément Bosquet, Pierre‐Philippe Combes, Cecilia García‐Peñalosa Gender and Promotions: ...
Tópico(s): Fiscal Policy and Economic Growth
1974 - University of Chicago Press | Journal of Political Economy
W. Lee Hansen, Burton A. Weisbrod, Robert P. Strauss,
... 371.https://doi.org/10.1111/caje.12077Clément Bosquet, Pierre-Philippe Combes Are academics who publish more also ...
Tópico(s): Monetary Policy and Economic Impact
1978 - University of Chicago Press | Journal of Political Economy
Béatrice Jacquelin, Gaël Petitjean, Désirée Kunkel, Anne-Sophie Liovat, Simon P. Jochems, Kenneth A. Rogers, Mickaël J. Ploquin, Yoann Madec, Françoise Barré‐Sinoussi, Nathalie Dereuddre‐Bosquet, Pierre Lebon, Roger Le Grand, François Villinger, Michaela Müller‐Trutwin,
Chronic immune activation (IA) is considered as the driving force of CD4+ T cell depletion and AIDS. Fundamental clues in the mechanisms that regulate IA could lie in natural hosts of SIV, such as African green monkeys (AGMs). Here we investigated the role of innate immune cells and IFN-α in the control of IA in AGMs. AGMs displayed significant NK cell activation upon SIVagm infection, which was correlated with the levels of IFN-α. Moreover, we detected cytotoxic NK cells in lymph nodes during the ...
Tópico(s): T-cell and B-cell Immunology
2014 - Public Library of Science | PLoS Pathogens
Clément Bosquet, Pierre‐Philippe Combes,
Thanks to a unique individual dataset of French academics in economics, we explain individual publication and citation records by gender and age, co-authorship patterns (average number of authors per article and size of the co-author network) and specialisation choices (percentage of output in each JEL code). The analysis is performed on both EconLit publication scores (adjusted for journal quality) and Google Scholar citation indexes, which allows us to present a broad picture of knowledge diffusion ...
Tópico(s): scientometrics and bibliometrics research
2013 - Springer Nature (Netherlands) | Scientometrics
Clément Bosquet, Pierre‐Philippe Combes,
Are agglomeration and peer effects at stake in academic research? To tackle this question, we study how departments' characteristics affect the quantity and quality of academics' publications in economics in France, controlling for individual time-varying characteristics and individual fixed effects. Department characteristics have an explanatory power at least equal to a quarter of that of individual characteristics and possibly as high as theirs. The quantity and quality of an academic's publications ...
Tópico(s): Economic Policies and Impacts
2017 - Elsevier BV | Journal of Urban Economics
Clément Bosquet, Pierre‐Philippe Combes, Cecilia García‐Peñalosa,
Abstract The promotion system for French academic economists provides an interesting environment to examine the promotion gap between men and women. Promotions occur through national competitions for which we have information both on candidates and on those eligible to be candidates. Thus, we can examine the two stages of the process: application and success. Women are less likely to seek promotion, and this accounts for up to 76 percent of the promotion gap. Being a woman also reduces the probability ...
Tópico(s): Gender Diversity and Inequality
2018 - Wiley | Scandinavian Journal of Economics
Clément Bosquet, Pierre‐Philippe Combes, Cecilia García‐Peñalosa,
Differences in promotion across genders are still prevalent in many occupations. Recent work based on experimental evidence indicates that women participate less in or exert lower effort during contests. We exploit the unique features of the promotion system for French academics to look at women's attitudes towards competition in an actual labour market. Using data for academic economists over the period 1991-2008 we find that, conditional on entering the competition, there is no difference in promotions ...
Tópico(s): Experimental Behavioral Economics Studies
2013 - RELX Group (Netherlands) | SSRN Electronic Journal
Christine Libon, Isabelle Vandenberghe, Romain Marlin, Wesley Gros, Marco Leonec, Mario Gomez-Pacheco, Anne-Sophie Gallouët, Françoise Fraboul, Abderrahim Mahfoudi, Nathalie Dereuddre‐Bosquet, Pierre Ferré,
... Sophie Gallouet, Françoise Fraboul, Abderrahim Mahfoudi, Nathalie Dereuddre-Bosquet, Pierre Ferré. K0401-020 anti-VISTA antibody monotherapy increases ...
Tópico(s): Immune Cell Function and Interaction
2020 - American Association for Cancer Research | Cancer Research
Marina Moreau, Anna Le Tortorec, Claire Deléage, Charles R. Brown, Hélène Denis, Anne-Pascale Satié, Olivier Bourry, Nathalie Deureuddre-Bosquet, Pierre Roques, Roger Le Grand, Nathalie Dejucq‐Rainsford,
Background The male genital tract is suspected to constitute a viral sanctuary as persistent HIV shedding is found in the semen of a subset of HIV-infected men receiving effective antiretroviral therapy (HAART). The origin of this persistent shedding is currently unknown. Phylogenetic studies indicated that HIV in semen from untreated men arises from local sources and/or passive diffusion from the blood. We previously demonstrated in human and macaque low levels and localized infection of several ...
Tópico(s): HIV/AIDS drug development and treatment
2012 - Public Library of Science | PLoS ONE
Olivier Bourry, Abdelkrim Mannioui, Pierre Sellier, Camille Roucairol, Lucie Durand‐Gasselin, Nathalie Dereuddre‐Bosquet, Henri Bénech, Pierre Roques, Roger Le Grand,
HIV reservoirs are rapidly established after infection, and the effect of HAART initiated very early during acute infection on HIV reservoirs remains poorly documented, particularly in tissue known to actively replicate the virus. In this context, we used the model of experimental infection of macaques with pathogenic SIV to assess in different tissues: (i) the effect of a short term HAART initiated at different stages during acute infection on viral dissemination and replication, and (ii) the local ...
Tópico(s): HIV/AIDS Research and Interventions
2010 - BioMed Central | Retrovirology
François Potdevin, V. Femery, A. Decatoire, Laurent Bosquet, Yann Coello, Pierre Moretto,
In the literature, numerous statistical analyses are used to quantify asymmetry in gait.This study tested the effect size (ES) statistic for quantifying asymmetry in nondisabled and pathological populations.The plantar pressure peaks on eight footprint locations of 27 nondisabled subjects and 18 patients with hemiparesis were bilaterally compared.Asymmetry quantifications were performed with ES and standard statistical tests (index of asymmetry, symmetry index, and ratio index).The results show an ...
Tópico(s): Balance, Gait, and Falls Prevention
2007 - United States Department of Veterans Affairs | The Journal of Rehabilitation Research and Development
Romain Bosquet, Agnès Jullien, Pierre‐Olivier Vandanjon, Michel Dauvergne, F. Javier Sánchez,
In accordance with the environmental concerns that national policies still address throughout the world, railways have been extensively studied to provide quantified indicators for assessing construction/operations practices. It is essential to take energy consumption, into account since energy can be measured worldwide, in addition to constituting a global environmental load that is time-limited as regards resource availability and known as a discriminating criterion in comparing transport infrastructure. ...
Tópico(s): Railway Engineering and Dynamics
2014 - Elsevier BV | Transportation Research Part D Transport and Environment
Roger Le Grand, Bruno Vaslin, Jérôme Larghero, Olivier Neidez, Hugues Thiébot, Pierre Sellier, Pascal Clayette, N Dereuddre-Bosquet, Dominique Dormont,
... Bruno Vaslin Jérome Larghero Olivier Neidez Hugues Thiebot Pierre Sellier Pascal Clayette Nathalie Dereuddre-Bosquet Dominique Dormont
Tópico(s): HIV, Drug Use, Sexual Risk
2000 - Lippincott Williams & Wilkins | AIDS
Pierre Sellier, Abdelkrim Mannioui, Olivier Bourry, Nathalie Dereuddre‐Bosquet, Benoît Delache, Patricia Brochard, Julien Calvo, Sophie Prévôt, Pierre Roques,
Background The time of infection is rarely known in human cases; thus, the effects of delaying the initiation of antiretroviral therapy (ART) on the peripheral viral load and the establishment of viral reservoirs are poorly understood. Methodology/Principal Findings Six groups of macaques, infected intravenously with SIVmac251, were given placebo or antiretroviral therapy to explore reservoir establishment; macaques were treated for 2 weeks, with treatment starting 4 hours, 7 or 14 days after infection. ...
Tópico(s): HIV/AIDS drug development and treatment
2010 - Public Library of Science | PLoS ONE
Clément Bosquet, Pierre‐Philippe Combes,
Nous utilisons les citations Google Scholar 2010 des économistes exerçants en France en 2008 afin de dessiner un panorama de la recherche en économie en France et de tester l’utilisation d’un support plus large qu’Econlit pour l’évaluation de la production de recherche. Nous comparons les indicateurs de citations tels que le nombre de citations divisés par le nombre d’auteurs, l’indice H ou l’indice G calculés au niveau individuel mais aussi des centres de recherche et universités avec des indices ...
Tópico(s): Cultural Insights and Digital Impacts
2012 - Editions Dalloz | Revue d économie politique
Clément Bosquet, Pierre-Philippe Combes, Cecilia García‐Peñalosa, Sarra Ben Yahmed, Camille Dufour,
En se concentrant sur le milieu académique français, les auteurs cherchent à expliquer la sous-représentation des femmes dans les postes se situant au sommet de la hiérarchie. Trois hypothèses sont testées : la discrimination à l’encontre des femmes dans le processus de promotion, les différences de comportement en situation de compétition et les moindres performances des femmes aux épreuves de concours. Les auteurs exploitent une base de données riche qui renseigne les caractéristiques des candidats, ...
Tópico(s): Labor market dynamics and wage inequality
2014 - | Regards croisés sur l'économie/Regards croisés sur l'économie
Olivier Épaulard, Lucille Adam, Candice Poux, Gérard Zurawski, Nina Salabert, Pierre Rosenbaum, Nathalie Dereuddre‐Bosquet, Sandra Zurawski, Anne-Laure Flamar, SangKon Oh, Gabrielle Romain, Catherine Chapon, Jacques Banchereau, Yves Lévy, Roger Le Grand, Frédéric Martinon,
Dendritic cells are major APCs that can efficiently prime immune responses. However, the roles of skin-resident Langerhans cells (LCs) in eliciting immune responses have not been fully understood. In this study, we demonstrate for the first time, to our knowledge, that LCs in cynomolgus macaque skin are capable of inducing antiviral-specific immune responses in vivo. Targeting HIV-Gag or influenza hemagglutinin Ags to skin LCs using recombinant fusion proteins of anti-Langerin Ab and Ags resulted ...
Tópico(s): Immune Cell Function and Interaction
2014 - American Association of Immunologists | The Journal of Immunology
Jean‐Louis Palgen, Nicolas Tchitchek, Jamila Elhmouzi‐Younes, Simon Delandre, Inana Namet, Pierre Rosenbaum, Nathalie Dereuddre‐Bosquet, Frédéric Martinon, Antonio Cosma, Yves Lévy, Roger Le Grand, Anne‐Sophie Beignon,
Understanding the innate immune response to vaccination is critical in vaccine design. Here, we studied blood innate myeloid cells after first and second immunization of cynomolgus macaques with the modified vaccinia virus Ankara. The inflammation at the injection site was moderate and resolved faster after the boost. The blood concentration of inflammation markers increased after both injections but was lower after the boost. The numbers of neutrophils, monocytes, and dendritic cells were transiently ...
Tópico(s): Immune cells in cancer
2018 - Nature Portfolio | Scientific Reports
Jean‐Louis Palgen, Nicolas Tchitchek, Nicolas Huot, Jamila Elhmouzi‐Younes, Cécile Lefebvre, Pierre Rosenbaum, Nathalie Dereuddre‐Bosquet, Frédéric Martinon, Hakim Hocini, Antonio Cosma, Michaela Müller‐Trutwin, Yves Lévy, Roger Le Grand, Anne‐Sophie Beignon,
Abstract A better understanding of innate responses induced by vaccination is critical for designing optimal vaccines. Here, we studied the diversity and dynamics of the NK cell compartment after prime-boost immunization with the modified vaccinia virus Ankara using cynomolgus macaques as a model. Mass cytometry was used to deeply characterize blood NK cells. The NK cell subphenotype composition was modified by the prime. Certain phenotypic changes induced by the prime were maintained over time ...
Tópico(s): Immunotherapy and Immune Responses
2019 - Oxford University Press | Journal of Leukocyte Biology
Armelle Roisin, Jean-Philippe Robin, Nathalie Dereuddre‐Bosquet, Anne-Laure Vitte, Dominique Dormont, Pascal Clayette, Pierre Jalinot,
New therapeutic agents able to block HIV-1 replication are eagerly sought after to increase the possibilities of treatment of resistant viral strains. In this report, we describe a rational strategy to identify small peptide sequences owning the dual property of penetrating within lymphocytes and of binding to a protein target. Such sequences were identified for two important HIV-1 regulatory proteins, Tat and Rev. Their association to a stabilizing domain consisting of human small ubiquitin-related ...
Tópico(s): Immune Cell Function and Interaction
2004 - Elsevier BV | Journal of Biological Chemistry
Timothée Bruel, Chiraz Hamimi, Nathalie Dereuddre‐Bosquet, Antonio Cosma, So Youn Shin, Aurélien Corneau, Pierre Versmisse, Ingrid Karlsson, Benoît Malleret, Brice Targat, Françoise Barré‐Sinoussi, Roger Le Grand, Gianfranco Pancino, Asier Sáez‐Cirión, Bruno Vaslin,
The spontaneous control of human and simian immunodeficiency viruses (HIV/SIV) is typically associated with specific major histocompatibility complex (MHC) class I alleles and efficient CD8(+) T-cell responses, but many controllers maintain viral control despite a nonprotective MHC background and weak CD8(+) T-cell responses. Therefore, the contribution of this response to maintaining long-term viral control remains unclear. To address this question, we transiently depleted CD8(+) T cells from five ...
Tópico(s): HIV/AIDS Research and Interventions
2015 - American Society for Microbiology | Journal of Virology
Lamine Alaoui, Gustavo Martelli Palomino, Sandy Zurawski, Gérard Zurawski, Sixtine Coindre, Nathalie Dereuddre‐Bosquet, Camille Lécuroux, Cécile Goujard, Bruno Vaslin, Christine Bourgeois, Pierre Roques, Roger Le Grand, Olivier Lambotte, Benoı̂t Favier,
Tópico(s): T-cell and B-cell Immunology
2017 - Springer Nature | Cellular and Molecular Life Sciences
Pierre Roques, Andrea Fritzer, Nathalie Dereuddre‐Bosquet, Nina Wressnigg, Romana Hochreiter, Laëtitia Bossevot, Quentin Pascal, Fabienne Guéhenneux, Annegret Bitzer, Irena Corbic Ramljak, Roger Le Grand, Urban Lundberg, Andreas Meinke,
Chikungunya virus (CHIKV) is a reemerging mosquito-borne alphavirus responsible for numerous outbreaks. Chikungunya can cause debilitating acute and chronic disease. Thus, the development of a safe and effective CHIKV vaccine is an urgent global health priority. This study evaluated the effectiveness of the live-attenuated CHIKV vaccine VLA1553 against WT CHIKV infection by using passive transfer of sera from vaccinated volunteers to nonhuman primates (NHP) subsequently exposed to WT CHIKV and established ...
Tópico(s): Viral Infections and Vectors
2022 - American Society for Clinical Investigation | JCI Insight
Clément Bosquet, Pierre‐Philippe Combes, Emeric Henry, Thierry Mayer,
Abstract Using an instrument based on a national contest in France determining researchers’ location, we find evidence of peer effects in academia, when focusing on precise groups of senders (producing the spillovers) and receivers (benefiting from the spillovers), defined based on field of specialisation, gender and age. These peer effects are present even outside formal co-authorship relationships. Furthermore, the match between the characteristics of senders and receivers plays a critical role. ...
Tópico(s): scientometrics and bibliometrics research
2022 - Oxford University Press | The Economic Journal
Selma Bekri, Pierre Bourdely, Carmelo Luci, Nathalie Dereuddre‐Bosquet, Bin Su, Frédéric Martinon, Véronique M. Braud, Irene Luque, Pedro L. Mateo, Sara Crespillo, Francisco Conejero‐Lara, Christiane Moog, Roger Le Grand, Fabienne Anjuère,
Persistent B cell responses in mucosal tissues are crucial to control infection against sexually transmitted pathogens like Human Immunodeficiency Virus 1 (HIV-1). The genital tract is a major site of infection by HIV. Sublingual immunization in mice was previously shown to generate HIV-specific B cell immunity that disseminates to the genital tract. We report here the immunogenicity in female cynomolgus macaques of a sublingual vaccine based on a modified gp41 polypeptide coupled to the cholera ...
Tópico(s): T-cell and B-cell Immunology
2017 - Frontiers Media | Frontiers in Immunology
Mickaël J. Ploquin, Yoann Madec, Armanda Casrouge, Nicolas Huot, Caroline Passaes, Camille Lécuroux, Asma Essat, Faroudy Boufassa, Béatrice Jacquelin, Simon P. Jochems, Gaël Petitjean, Mathieu Angin, Kathleen Gärtner, Thalía García-Téllez, Nicolas Noël, Thijs Booiman, Brigitte Boeser‐Nunnink, Pierre Roques, Asier Sáez‐Cirión, Bruno Vaslin, Nathalie Dereudre-Bosquet, Françoise Barré‐Sinoussi, Mathilde Ghislain, Christine Rouzioux, Olivier Lambotte, Matthew L. Albert, Cécile Goujard, Neeltje A. Kootstra, Laurence Meyer, Michaela Müller‐Trutwin,
Elevated blood CXCL10/IP-10 levels during primary HIV-1 infection (PHI) were described as an independent marker of rapid disease onset, more robust than peak viremia or CD4 cell nadir. IP-10 enhances the recruitment of CXCR3+ cells, which include major HIV-target cells, raising the question if it promotes the establishment of viral reservoirs. We analyzed data from four cohorts of HIV+ patients, allowing us to study IP-10 levels before infection (Amsterdam cohort), as well as during controlled and ...
Tópico(s): Immune Cell Function and Interaction
2016 - Public Library of Science | PLoS Pathogens
R.H. Bourgain, C. Deby, P. Braquet, D Bosquet,
Bourgain, Renè H.; Deby, Carol*; Braquet, Pierre†; Bosquet, Dominique‡ Author Information
Tópico(s): Blood Coagulation and Thrombosis Mechanisms
1988 - Lippincott Williams & Wilkins | Journal of Hypertension
Pierre Roques, Karl Ljungberg, Beate M. Kümmerer, Laurent Gosse, Nathalie Dereuddre‐Bosquet, Nicolas Tchitchek, David Hallengärd, Juan García‐Arriaza, Andreas Meinke, Mariano Estéban, Andres Merits, Roger Le Grand, Peter Liljeström,
Chikungunya virus (CHIKV) is rapidly spreading across the globe, and millions are infected. Morbidity due to this virus is a serious threat to public health, but at present, there is no vaccine against this debilitating disease. We have recently developed a number of vaccine candidates, and here we have evaluated 3 of them in a nonhuman primate model. A single immunization with an attenuated strain of CHIKV (Δ5nsP3), a homologous prime-boost immunization with a DNA-launched RNA replicon encoding CHIKV ...
Tópico(s): Virology and Viral Diseases
2017 - American Society for Clinical Investigation | JCI Insight
Petros Andrikopoulos, Judith Aron‐Wisnewsky, Rima Chakaroun, Antonis Myridakis, Sofia K. Forslund, Trine Nielsen, Solia Adriouch, Bridget Holmes, Julien Chilloux, Sara Vieira‐Silva, Gwen Falony, Joe-Élie Salem, Fabrizio Andreelli, Eugeni Belda, Julius Kieswich, Kanta Chechi, Francesc Puig‐Castellví, Mickaël Chevalier, Emmanuelle Le Chatelier, Michael Olanipekun, Lesley Hoyles, Renato Alves, Gérard Helft, Richard Isnard, Lars Køber, Luís Pedro Coelho, Christine Rouault, Dominique Gauguier, Jens Peter Gøtze, Edi Prifti, Philippe Froguel, Rohia Alili, Ehm Astrid Andersson Galijatovic, Olivier Barthélemy, Jean‐Philippe Bastard, Jean-Paul Batisse, Pierre Bel-Lassen, Magali Berland, Randa Bittar, Hervé M. Blottière, F Bosquet, Rachid Boubrit, Olivier Bourron, Mickaël Camus, Cécile Ciangura, Jean‐Philippe Collet, Arne Dietrich, Morad Djebbar, Angélique Doré, Line Engelbrechtsen, Léopold Fezeu, Sébastien Fromentin, Nicolas Pons, Marianne Graine, Caroline Grünemann, Agnès Hartemann, Bolette Hartmann, Malene Hornbak, Sophie Jaqueminet, Niklas Rye Jørgensen, Hanna Julienne, Johanne Marie Justesen, Judith Kammer, Nikolaj Karup, Ruby Kozlowski, Michael Kuhn, Véronique Lejard, Ivica Letunić, Florence Levenez, Lajos Markó, Laura Martinez‐Gili, Robin Massey, Nicolas Maziers, Lucas Moitinho‐Silva, Gilles Montalescot, Ana Luísa Neves, Laetitia Pasero Le Pavin, Françoise Pousset, Andrea Rodriguez‐Martinez, Sebastien Schmidt, Tatjana Schütz, Lucas F. M. da Silva, Johanne Silvain, Mathilde Svendstrup, T.D. Swartz, Thierry Vanduyvenboden, Eric O. Verger, Stefanie Walther, Jean‐Daniel Zucker, Fredrik Bäckhed, Henrik Vestergaard, Torben Hansen, Jean‐Michel Oppert, Matthias Blüher, Jens Nielsen, Jeroen Raes, Peer Bork, Muhammad M. Yaqoob, Michael Stümvoll, Oluf Pedersen, S. Dusko Ehrlich, Karine Clément, Marc‐Emmanuel Dumas,
The host-microbiota co-metabolite trimethylamine N-oxide (TMAO) is linked to increased cardiovascular risk but how its circulating levels are regulated remains unclear. We applied "explainable" machine learning, univariate, multivariate and mediation analyses of fasting plasma TMAO concentration and a multitude of phenotypes in 1,741 adult Europeans of the MetaCardis study. Here we show that next to age, kidney function is the primary variable predicting circulating TMAO, with microbiota composition ...
Tópico(s): Renal function and acid-base balance
2023 - Nature Portfolio | Nature Communications
René‐Jean Bensadoun, Clotilde Allavena, Patrick Chauvel, O. Dassonville, F Démard, L. Dieu-Bosquet, Jean Lacau St Guily, F. Ettore, G Gory-Delabaere, Pierre‐Yves Marcy, É. Reyt,
The "Standards, Options and Recommendations" (SOR) project, which started in 1993, is a collaboration between the Federation of French Cancer Centers (FNCLCC), the 20 French Regional Cancer Centers. and specialists from French public universities,general hospitals and private clinics. The main objective is the development of clinical practice guidelines to improve the quality of health care and the outcome of cancer patients.To update clinical practice guidelines for the management of patients with ...
Tópico(s): Oral and Maxillofacial Pathology
2003 - Elsevier BV | Cancer/Radiothérapie