A. Krzywicki, Piotr P. Słonimski,
Abstract A thorough formal investigation of pair correlations between amino acids in various protein sequences is performed. To this end we apply a particularly sensitive method of statistical analysis. An evidence is given for the existence of correlations between amino acids separated, along the polypeptide chain, by 5 and 6 and by 28 and 29 peptide bonds. We discuss the chemical nature of these correlations and their possible relation to the three-dimensional structure of proteins.
Tópico(s): Protein Structure and Dynamics
1967 - Elsevier BV | Journal of Theoretical Biology
Wojciech Turek, Jan Stypka, Daniel Krzywicki, Piotr Anielski, Kamil Piętak, Aleksander Byrski, Marek Kisiel‐Dorohinicki,
Difficult search and optimization problems, usually solved by metaheuristics, are very often implemented in concurrent and parallel environment, as many metaheuristics (e.g. population- or agent-based) are inherently easy to parallelize. Therefore search for easy-to-use, robust and efficient frameworks dedicated for such computing methods, especially in the era of ubiquitous many and multi-core systems, is very desirable. Indeed, the development of multi-core architectures is incredibly fast and ...
Tópico(s): Multi-Agent Systems and Negotiation
2016 - Elsevier BV | Journal of Computational Science
Tomasz Krzywicki, Piotr Brona, Agnieszka M. Zbrzezny, Andrzej Grzybowski,
This article provides a comprehensive and up-to-date overview of the repositories that contain color fundus images. We analyzed them regarding availability and legality, presented the datasets' characteristics, and identified labeled and unlabeled image sets. This study aimed to complete all publicly available color fundus image datasets to create a central catalog of available color fundus image datasets.
Tópico(s): Retinal and Optic Conditions
2023 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine
A. Krzywicki, Piotr P. Słonimski,
Tópico(s): Machine Learning in Bioinformatics
1968 - Elsevier BV | Journal of Theoretical Biology
Andrzej Grzybowski, Divya Parthasarathy Rao, Piotr Brona, Kalpa Negiloni, Tomasz Krzywicki, Florian M. Savoy,
Numerous studies have demonstrated the use of artificial intelligence (AI) for early detection of referable diabetic retinopathy (RDR). A direct comparison of these multiple automated diabetic retinopathy (DR) image assessment softwares (ARIAs) is, however, challenging. We retrospectively compared the performance of two modern ARIAs, IDx-DR and Medios AI.In this retrospective-comparative study, retinal images with sufficient image quality were run on both ARIAs. They were captured in 811 consecutive ...
Tópico(s): Acute Ischemic Stroke Management
2023 - Karger Publishers | Ophthalmic Research
Wiesław Kopeć, Marcin Wichrowski, Krzysztof Kalinowski, Anna Jaskulska, Kinga Skorupska, Daniel Cnotkowski, Jakub Tyszka, Agata Popieluch, Anna Voitenkova, Rafał Masłyk, Piotr Gago, Maciej Krzywicki, Monika Kornacka, Cezary Biele, Paweł Kobyliński, Jarosław Kowalski, Katarzyna Abramczuk, Aldona Zdrodowska, Grzegorz Pochwatko, Jakub Możaryn, Krzysztof Marasek,
In this paper we report on a study conducted with a group of older adults in which they engaged in participatory design workshops to create a VR ATM training simulation. Based on observation, recordings and the developed VR application we present the results of the workshops and offer considerations and recommendations for organizing opportunities for end users, in this case older adults, to directly engage in co-creation of cutting-edge ICT solutions. These include co-designing interfaces and interaction ...
Tópico(s): Technology Use by Older Adults
2019 - Elsevier BV | IFAC-PapersOnLine
Piotr Biler, A. Krzywicki, Tadeusz Nadzieja,
We propose some nonlinear parabolic-elliptic systems modelling the evolution of the density of particles (charged or massive) interacting with themselves, and coupled to a temperature field. These models are thermodynamically consistent, i.e., they obey the first and the second laws of thermodynamics. We study their steady states and the asymptotic behaviour for large time.
Tópico(s): Stochastic processes and statistical mechanics
1998 - Elsevier BV | Reports on Mathematical Physics
Daniel Krzywicki, Jan Stypka, Piotr Anielski, Łukasz Faber, Wojciech Turek, Aleksander Byrski, Marek Kisiel‐Dorohinicki,
Metaheuristics resulting from the hybridization of multi-agent systems with evolutionary computing are efficient in many optimization problems. Evolutionary multi-agent systems (EMAS) are more similar to biological evolution than classical evolutionary algorithms. However, technological limitations prevented the use of fully asynchronous agents in previous EMAS implementations. In this paper we present a new algorithm for agent-based evolutionary computations. The individuals are represented as fully ...
Tópico(s): Mobile Agent-Based Network Management
2014 - Elsevier BV | Procedia Computer Science
Andrzej Grzybowski, Piotr Brona, Tomasz Krzywicki, Magdalena Gaca-Wysocka, Arleta Berlińska, Anna Święch-Zubilewicz,
Poland has never had a widespread diabetic retinopathy (DR) screening program and subsequently has no purpose-trained graders and no established grader training scheme. Herein, we compare the performance and variability of three retinal specialists with no additional DR grading training in assessing images from 335 real-life screening encounters and contrast their performance against IDx-DR, a US Food and Drug Administration (FDA) approved DR screening suite. A total of 1501 fundus images from 670 ...
Tópico(s): Glaucoma and retinal disorders
2022 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine
Pedro Barrera-Baena, Minerva Rodríguez-García, Enrique Rodríguez-Rubio, Lucía González-Llorente, Alberto Ortíz, Carmine Zoccali, Francesco Locatelli, Jürgen Floege, Martine Cohen‐Solal, Aníbal Ferreira, Markus Ketteler, Gérard M. London, José Luis Górriz, J. Emilio Sánchez-Álvarez, Miguel Ángel Hevia-Suárez, J.M. Fernández Gómez, Beatriz Martín-Carro, Carlos Gómez‐Alonso, Cristina Alonso‐Montes, Jorge B. Cannata‐Andía, José Luis Fernández Martín, L Marosi, Allgemeines Krankenhaus, Bernhard Robl, Heinrich Kiss, Ulrich Neyer, Wilfried Jilly, Kramar, Dierik Verbeelen, Anne Wauters, R Cuvelier, C M De Mouscron, Max Dratwa, Chu Brugmann, Christian Tielemans, F. Dehout, Pierre Claus, A. Dhondt, B Jeren-Strujić, Marijana Gulin, Valentina Čorić-Martinović, Draško Pavlović, Jana Smržová, Pavlikova, Valkovsky, Zahradnik, Vladimı́r Teplan, Pavukova, Nemocnice Poliklinikou, Dialyzacni Stredisko, Moucka Nemocnice, Overlæge Kjeld Otte, Fredericia Sygehus, James Heaf, Overlæge Henning Danielsen, Viborg Sygehus, Mari Kolunen, L L Markku Asola, Philit Jean-Baptiste, Philippe Nicoud, François-Louis Maurice, Mohamed Brahim Bounab, Philippe Bertocchio, Guillaume Jean, Bony Chantal, Pierre Grimal, J. Gaultier, Alex Mouneimne, Brignon, Dupuy, Jean-Paul Jaulin, Pablo Ureña, Marc Pocheville, Valérie Masson, Marc Uzan, Dominique Besnier, M Labeeuw, Głowacki, Cattanéo, Bois Guillaume, D Didier, Bouchouareb, Petitjean Philippe, Dahmane Djamel, A N G Kim-Seng, Saveanu, Gérard M. London, Bouali Boussad, François-Pascal Wambergue, J.F. de Frémont, Michel, P Giraud, Jean-Paul Eche, Bernard S. López, Catherine Delcroix, Duchet, Ghandour Majdalani, Guy, Hadj, Marie-Paule Guillodo, Jochen Selbach, Arnold Röckel, B. Krumme, Bolley, M Grieger, Won-Ho Hahn, M. Daschner, Beate Iwig, Susanne Arendt, Dieter Berger, Bernd Wölbert, H Holzmann, Guenther Graf, Carsten Brockmann, W. J. Brech, A Mandelbaum, Wolfang Lauerwald, Johannes Bunia, Ulrich Lammer, Diep Thanh Au, Carsten Kurth, Schnierda, Stolz, Joachim Harlos, Steffen Berweck, Karl-August Brensing, Karl-August Brensing, Burkhard Kreft, Heinrich Jahnz, W. Kohnle, Wilfried Kamen, Sodemann, Peter Nachtigall, Jürgen Schäffer, Leimenstoll, K. Stenger, Wollschläger, Christine Langer, W Clasen, Christoph Röger, Klaus Burkhardt, J. P. Steinbach, Walter Schulz, Wolfgang Pommer, Michael Wilfling, Karla Schmaltz, Michael Eichhorn, B. L. Oser, E. Müller, Carola Striebing, H Schobel, Wolfgang Ludwig, Ulrich Frei, Helmut Peter Becker, Hans-Christoph Fischer, Maximilian Goller, Dieter Brückner, G Janning, Wolfgang Bagnewski, H. Preßler, Christoph C. Haufe, P. Grützmacher, Hans-Joachim Miska, Tomas Lenz, Olaf Frank Hoeft, Rolfdieter Krause, Kirsten de Groot, H. Armbruster, Peter Spellerberg, Wolfgang Stützer, Josef Nikolay, Rüdiger Schmidt, Johannes F.E. Mann, Rainer Roth, Johann-Borwin Lüth, Sybille Merscher, Hans-Jürgen Schmidt-Gürtler, Wolfgang Groß, Dehnert, Eva Roth, Jürgen Floege, Markus Ketteler, Stefan Heidenreich, Günter Bahlmann, Olaf Loke, Matthias Becker, Rolf Ebbinghaus, Matthias Weiß, Berhard Frye, F Matzkies, Katrin Gebauer, H-J Schurek, M. Heck, Helge Hohage, Ullrich Welling, M. Zeh, Schwietzer, Hermann Haller, Jochen Selbach, U. Metz-Kurschel, Roland Fulde, Christoph Ganzemüller, Jörg Radermacher, Joachim Materna, Oliver Hebgen, Bernhard Weber, Dieter Hummel, Scheuerle, Horst Kierdorf, Horst Kierdorf, Joachim Beige, Ralf Lorenz, Dimitrios Plakias, Stauroula Solomakou, Georgios Bristogiannis, Kleonikos Kalaitzidis, Dimitrios Kavvadias, Dimitrios Memmos, Antonis Papantoniou, Kyriaki Stamatelou, Ioannis Stefanidis, Konstantinos Siamopoulos, Csaba Rikker, Imre Kulcsár, B. Tichy, Sándor Ferenczi, Andrea Hering, Ottó Árkossy, Judit Nagy, Ascanio de Gregorio, Gianmaria Frattini, Antonio La Corte, Ugo Rotolo, Diego Brancaccio, Maurizio Gallieni, Fusaro, A Albertazzi, Livia Nazzaro, Francesco Randazzo, Francesco Locatelli, C Lodeserto, Angela D’Angelo, Giovanni M. Frascà, Fabio Malberti, Deni Aldo Procaccini, Cesare Dell, Goffredo Del Rosso, E Dialisi, Spotti Donatella, Giuseppe Bianchi, Marco Biagini, Filippo Aucella, Antonio Scarlatella, A Jeantet, E Dialisi, Marco Farina, Canulla Francesco, Maria Vittoria Cossu, Ssa Gina Meneghel, Mario Bonomini, Roberto Palla, Morosetti Massimo, Giancarlo Marinangeli, Rosella Estivi, Martin Giuliano, Antonio Santoro Md Poloclinico S Orsola-Malpighi, Renzo Scanziani, Conte Ferruccio, Giorgio Munatetto, Pastori Giordano, Giacomino Rossi, L Cagnoli, L Cagnoli, Massimo Morossetti, D Plutino, Alberto Galbiati, Loreto Gesualdo, M Querques, Giacomo Colussi, U Nefrologia, Andrea Macchi, Adalberto Tommasi, Eric F.H. van Bommel, Willem Jan W. Bos, Gaico H. Verseput, Louis Jean Vleming, C T Op De Hoek, Henk W. van Hamersvelt, Femke Hoekstra, H. A. H. Kaasjager, Magdalena Durlik, Miroslav Grzeszczyk, Andrzej Rydzewski, Dorota Śliwicka, Antoni Sydor, Tadeusz Gauda,
ABSTRACT Background Bone fragility fractures are associated with high morbidity and mortality. This study analysed the association between the current biochemical parameters of chronic kidney disease–mineral and bone disorders (CKD-MBD) and bone fragility fractures in the COSMOS (Current management Of Secondary hyperparathyroidism: a Multicentre Observational Study) project. Methods COSMOS is a 3-year, multicentre, open cohort, prospective, observational study carried out in 6797 haemodialysis patients ( ...
Oxford University Press
Tópico(s): Diverse Academic Research Studies
2003 - John Paul II Catholic University of Lublin | Roczniki Psychologiczne
Andrzej Grzybowski, Piotr Brona, Tomasz Krzywicki, Paisan Ruamviboonsuk,
Abstract Introduction Automated diabetic retinopathy (DR) screening using artificial intelligence has the potential to improve access to eye care by enabling large-scale screening. However, little is known about differences in real-world performance between available algorithms. This study compares the diagnostic accuracy of two AI screening platforms, IDx-DR and RetCAD, for detecting referable diabetic retinopathy (RDR). Methods Retinal images from 758 patients with diabetes were collected during ...
Tópico(s): Retinal and Optic Conditions
2024 - Adis, Springer Healthcare | Ophthalmology and Therapy
A. Dyonizy, Vitaliy Kaminker, Joanna Wieckowska, Tomasz Krzywicki, Jim Pantaleone, Piotr Nowak, Jerzy Masełko,
Biological structures grow spontaneously from a seed, using materials supplied by the environment. These structures are hierarchical, with the 'building blocks' on each level constructed from those on the lower level. To understand and model the processes that occur on many levels, and later construct them, is a difficult task. However interest in this subject is growing. It is now possible to study the spontaneous growth of hierarchical structures in simple, two component chemical systems.Aluminum- ...
Tópico(s): Nonlinear Dynamics and Pattern Formation
2015 - Chemistry Central | Journal of Systems Chemistry
Kinga Skorupska, R. Stryjek, Izabela A. Wierzbowska, Piotr Bębas, Maciej Grzeszczuk, Piotr Gago, Jarosław Kowalski, Maciej Krzywicki, Jagoda Łazarek, Wiesław Kopeć,
Tópico(s): Animal Ecology and Behavior Studies
2024 - Springer International Publishing | Lecture notes in networks and systems
Andrzej Grzybowski, Freya Peeters, Rafael Correia Barão, Piotr Brona, Stef Rommes, Tomasz Krzywicki, Ingeborg Stalmans, Julie A. Jacob,
Abstract Purpose To compare two artificial intelligence (AI)‐based Automated Diabetic Retinopathy Image Assessment (ARIA) softwares in terms of concordance with specialist human graders and referable diabetic retinopathy (DR) diagnostic capacity. Methods Retrospective comparative study including 750 consecutive diabetes mellitus patients imaged for non‐mydriatic fundus photographs. For each patient four images (45 degrees field of view) were captured, centered on the optic disc and macula. Images were ...
Tópico(s): Retinal and Optic Conditions
2024 - Wiley | Acta Ophthalmologica
Clara Sanz-García, Minerva Rodríguez-García, José Luis Górriz, Beatriz Martín-Carro, Jürgen Floege, B. Díaz-López, Carmen Palomo-Antequera, J. Emilio Sánchez-Álvarez, Carlos Gómez‐Alonso, J.M. Fernández Gómez, Miguel Ángel Hevia-Suárez, Juan F. Navarro‐González, María Dolores Arenas, Francesco Locatelli, Carmine Zoccali, Aníbal Ferreira, Cristina Alonso‐Montes, Jorge B. Cannata‐Andía, Juan Jesús Carrero, José Luis Fernández Martín, L Marosi, Allgemeines Krankenhaus, Bernhard Robl, Heinrich Kiss, Ulrich Neyer, Wilfried Jilly, Kramar, Dierik Verbeelen, Anne Wauters, R Cuvelier, Max Dratwa, Christian Tielemans, F. Dehout, Pierre Claus, A. Dhondt, B Jeren-Strujić, Marijana Gulin, Valentina Čorić-Martinović, Draško Pavlović, Jana Smržová, Pavlikova, Valkovsky, Zahradnik, Vladimı́r Teplan, Stranik, Pavukova, Moucka, Overlæge Kjeld Otte, James Heaf, Mari Kolunen, Philit Jean-Baptiste, Philippe Nicoud, François-Louis Maurice, Mohamed Brahim Bounab, Philippe Bertocchio, Guillaume Jean, Bony Chantal, Daniel Tolédano, Pierre Grimal, J. Gaultier, Alex Mouneimne, Brignon, Dupuy, Jean-Paul Jaulin, Pablo Ureña, Marc Pocheville, Zins, Valérie Masson, Marc Uzan, Dominique Besnier, M Labeeuw, Głowacki, Cattanéo, D Didier, Bouchouareb, Petitjean Philippe, Dahmane Djamel, A N G Kim-Seng, Saveanu, Gérard M. London, Bouali Boussad, François-Pascal Wambergue, J.F. de Frémont, M Labeeuw, P Giraud, Jean-Paul Eche, Bernard S. López, Catherine Delcroix, Duchet, Ghandour Majdalani, Guy, Hadj, Marie-Paule Guillodo, Z A Du Questel, Jochen Selbach, Arnold Röckel, B. Krumme, Bolley, M Grieger, Won-Ho Hahn, M. Daschner, Beate Iwig, Susanne Arendt, Bernd Wölbert, H Holzmann, Guenther Graf, Carsten Brockmann, W. J. Brech, A Mandelbaum, Wolfang Lauerwald, Johannes Bunia, Ulrich Lammer, Carsten Kurth, Schnierda, Stolz, Joachim Harlos, Steffen Berweck, Karl-August Brensing, Karl-August Brensing, Burkhard Kreft, Heinrich Jahnz, W. Kohnle, Wilfried Kamen, Sodemann, Peter Nachtigall, Jürgen Schäffer, Leimenstoll, K. Stenger, Wollschläger, Christine Langer, W Clasen, Christoph Röger, Klaus Burkhardt, J. P. Steinbach, Walter Schulz, Wolfgang Pommer, Baerhausen, Michael Wilfling, Karla Schmaltz, Michael Eichhorn, B. L. Oser, E. Müller, Carola Striebing, H Schobel, Wolfgang Ludwig, Ulrich Frei, Helmut Peter Becker, Hans-Christoph Fischer, Maximilian Goller, Dieter Brückner, G Janning, Wolfgang Bagnewski, H. Preßler, Christoph C. Haufe, P. Grützmacher, Hans-Joachim Miska, Tomas Lenz, Olaf Frank Hoeft, Rolfdieter Krause, Kirsten de Groot, H. Armbruster, Klaus Kalkreuth, Peter Spellerberg, Wolfgang Stützer, Josef Nikolay, Rüdiger Schmidt, Johannes F.E. Mann, Rainer Roth, Johann-Borwin Lüth, Sybille Merscher, Hans-Jürgen Schmidt-Gürtler, Wolfgang Groß, Krankenhaus Bethanien, Dehnert, Eva Roth, Jürgen Floege, Markus Ketteler, Stefan Heidenreich, Günter Bahlmann, Olaf Loke, Matthias Becker, Rolf Ebbinghaus, Matthias Weiß, Berhard Frye, F Matzkies, Katrin Gebauer, H-J Schurek, M. Heck, Helge Hohage, Ullrich Welling, M. Zeh, Schwietzer, Hermann Haller, Jochen Selbach, Caritas-Krankenhaus, U. Metz-Kurschel, Roland Fulde, Christoph Ganzemüller, Jörg Radermacher, Joachim Materna, Oliver Hebgen, Bernhard Weber, Dieter Hummel, Scheuerle, Horst Kierdorf, Horst Kierdorf, Joachim Beige, Ralf Lorenz, Eckhardt Braasch, Dimitrios Plakias, Liamos, Stauroula Solomakou, Georgios Bristogiannis, Kleonikos Kalaitzidis, Dimitrios Kavvadias, Dimitrios Memmos, Antonis Papantoniou, Kyriaki Stamatelou, Ioannis Stefanidis, Konstantinos Siamopoulos, Csaba Rikker, Imre Kulcsár, B. Tichy, Sándor Ferenczi, Andrea Hering, Ottó Árkossy, Judit Nagy, Ascanio de Gregorio, Gianmaria Frattini, Antonio La Corte, Ugo Rotolo, D. Brancaccio, Maurizio Gallieni, Fusaro, A Albertazzi, Francesco Randazzo, Francesco Locatelli, C Lodeserto, Angela D’Angelo, Giovanni M. Frascà, Fabio Malberti, Aldo Deni Procaccini, Giuseppe Bianchi, Marco Biagini, Filippo Aucella, Antonio Scarlatella, Marco Farina, Ssa Gina Meneghel, Mario Bonomini, Roberto Palla, Morosetti Massimo, Giancarlo Marinangeli, Antonio Santoro, Giorgio Munatetto, Pastori Giordano, Giacomino Rossi, L Cagnoli, L Cagnoli, Massimo Morossetti, D Plutino, Alberto Galbiati, Loreto Gesualdo, M Querques, Adalberto Tommasi, Eric F.H. van Bommel, Willem Jan W. Bos, Gaico H. Verseput, Louis Jean Vleming, C T Op De Hoek, Henk W. van Hamersvelt, Femke Hoekstra, H. A. H. Kaasjager, Magdalena Durlik, Miroslav Grzeszczyk, Andrzej Rydzewski, Dorota Śliwicka, Janusz Ostrowski, Stacja Dializ Gambro, Antoni Sydor, Tadeusz Gauda, Malgorzata Figarska, Slawomir Trudnowski, Justyna Matulewicz-Gilewicz, Marek Sobocki, Jacek J Felisiak, Piotr Rutkowski, R Rudka, Kizysztof Bidas, Paweł Krzywicki, Jarosław Hawryluk, Krzysztof Dziewanowski, Cristina Resina, Fernando Carrera, Pedro Afonso Coelho Maia, J.F. Jiménez Cruz, Aníbal Ferreira,
Abstract Background Ageing often impacts on biomarker production. Yet, clinical/optimal thresholds to guide clinical decisions do not consider this. Serum albumin decreases with age, but hypoalbuminaemia is defined as serum albumin <4.0 g/dL. This study explores whether age might affect serum albumin levels and its association with mortality in haemodialysis patients. Methods COSMOS (Current management Of Secondary hyperparathyroidism: a Multicentre Observational Study) is a prospective, open cohort, ...
Oxford University Press
Jan Stypka, Piotr Anielski, Szymon Mentel, Daniel Krzywicki, Wojciech Turek, Aleksander Byrski, Marek Kisiel‐Dorohinicki,
Computing applications such as metaheuristics-based optimization can greatly benefit from multi-core architectures available on modern supercomputers. In this paper, we describe an easy and efficient way to implement certain population-based algorithms (in the discussed case, multi-agent computing system) on such runtime environments. Our solution is based on an Erlang software library which implements dedicated parallel patterns. We provide technological details on our approach and discuss experimental ...
Tópico(s): Data Mining Algorithms and Applications
2016 - Wydawnictwa AGH | Computer Science