Ola Blennow, Jan Vesterbacka, Tuulikki Tovatt, Piotr Nowak,
... this author on: Oxford Academic PubMed Google Scholar Piotr Nowak Piotr Nowak Department of Infectious Diseases, Karolinska University Hospital, Stockholm, ...
Tópico(s): Long-Term Effects of COVID-19
2023 - Oxford University Press | Clinical Infectious Diseases
Maruf M. U. Ali, Tina Bagratuni, Emma L. Davenport, Piotr Nowak, M. Cris Silva-Santisteban, Anthea Hardcastle, Craig McAndrews, Martin Rowlands, Gareth J. Morgan, Wynne Aherne, Ian Collins, Faith E. Davies, Laurence H. Pearl,
... for more papers by this author Piotr R Nowak Piotr R Nowak Division of Molecular Biosciences, Department of ... for more papers by this author Piotr R Nowak Piotr R Nowak Division of Molecular Biosciences, Department of Life Sciences, ...
Tópico(s): Virus-based gene therapy research
2011 - Springer Nature | The EMBO Journal
Marta Carrara, Filippo Prischi, Piotr R. Nowak, Maruf M. U. Ali,
... for more papers by this author Piotr R Nowak Piotr R Nowak Department of Life Sciences, Imperial College, ... for more papers by this author Piotr R Nowak Piotr R Nowak Department of Life Sciences, Imperial College, London, UK Search for more papers by this author Maruf MU Ali Corresponding Author Maruf MU Ali Department of Life Sciences, Imperial College, London, UK Search for more papers by this author Author Information Marta Carrara1,2, Filippo Prischi1, Piotr R Nowak1 and Maruf MU Ali 1 1Department ...
Tópico(s): Pancreatic function and diabetes
2015 - Springer Nature | The EMBO Journal
Thomas Müller, Yu Gao, Jinghua Wu, Oriana Ribeiro, Puran Chen, Peter Bergman, Ola Blennow, Lotta Hansson, Stephan Mielke, Piotr Nowak, Jan Vesterbacka, Mira Akber, Gunnar Söderdahl, Smith Rjh, Karin Loré, Margaret Chen, Per Ljungman, Hanna M. Ingelman-Sundberg, Hans‐Gustaf Ljunggren, Anders Österborg, Alessandro Sette, Alba Grifoni, Soo Aleman, Marcus Buggert,
T cells are critical in mediating the early control of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) breakthrough infection. However, it remains unknown whether memory T cells can effectively cross-recognize new SARS-CoV-2 variants with a broad array of mutations, such as the emergent hypermutated BA.2.86 variant. Here, we report in two separate cohorts, including healthy controls and individuals with chronic lymphocytic leukemia, that SARS-CoV-2 spike-specific CD4+ and CD8+ T cells ...
Tópico(s): vaccines and immunoinformatics approaches
2024 - Cell Press | Cell Host & Microbe
Agnieszka Wójtowicz, Anna Kolasa, Leszek Mościcki,
... and its Changes During Storage Mateusz Rogalski, Karolina Nowak, Piotr Fiedor, Arkadiusz Szterk Journal of the American Oil ...
Tópico(s): Microbial Metabolites in Food Biotechnology
2013 - De Gruyter Open | Polish Journal of Food and Nutrition Sciences
Anna Zasowska‐Nowak, Piotr Nowak, Aleksandra Ciałkowska-Rysz,
High-dose intravenously administered vitamin C (IVC) is widely used in cancer patients by complementary and alternative medicine practitioners. The most frequent indications for IVC therapy result from the belief in its effectiveness as a potent anti-cancer agent which additionally enhances chemosensitivity of cancer cells and reduces chemotherapy-related toxicities and fatigue intensity. In this narrative review, we decided to deal with this issue, trying to answer the question whether there is ...
Tópico(s): Complementary and Alternative Medicine Studies
2021 - Multidisciplinary Digital Publishing Institute | Nutrients
Wiesław Nowak, Piotr E. Marszałek,
... Simulations of Single Molecule Atomic Force Microscope ExperimentsWiesław Nowak and Piotr E. MarszałekWiesław NowakInstitute of Physics, Nicholaus Copernicus University, ...
Tópico(s): Surface and Thin Film Phenomena
2005 - World Scientific | Computational chemistry - reviews of current trends
Piotr Nowak, Radosław Wilk, Anna Prymont-Przymińska, Anna Zwolińska, Agata Sarniak, Anna Włodarczyk, Jeffrey de Graft‐Johnson, Beata Mamełka, Anna Zasowska‐Nowak, Piotr Bartnicki, Dariusz Nowak, Michał Nowicki,
Abstract Plant phenols may accumulate in end‐stage kidney disease. The effect of hemodialysis on their plasma concentration remains poorly determined. Contingent on concentration, health‐promoting or noxious effects occur; therefore, we assessed plasma concentration in hemodialyzed patients. In total, 21 maintenance hemodialyzed patients with diuresis < 500 mL per day (with oliguria), nine hemodialyzed patients with diuresis ≥ 500 mL per day (without oliguria) and 31 healthy volunteers were included. ...
Tópico(s): Antioxidant Activity and Oxidative Stress
2017 - Wiley | Therapeutic Apheresis and Dialysis
Ewa Drozdowicz, Michał Skalski, Paulina Gdańska, Anna Mach, Piotr Januszko, Rafał Nowak, Piotr Węgrzyn, Mirosław Wielgoś, Maria Radziwoń-Zaleska,
Tópico(s): Maternal Mental Health During Pregnancy and Postpartum
2017 - Springer Science+Business Media | Metabolic Brain Disease
Anna Zasowska‐Nowak, Piotr Nowak, Piotr Białasiewicz, Anna Prymont-Przymińska, Anna Zwolińska, Agata Sarniak, Anna Włodarczyk, J. Markowski, Krzysztof P. Rutkowski, Dariusz Nowak,
Objective: Strawberries can improve oxidants–antioxidants balance and reduce some cardiovascular risk factors in obese subjects. Paraoxonase-1 (PON-1) is a high-density lipoprotein–associated enzyme with antioxidant properties that can protect from coronary artery disease in humans. We examined the effect of strawberry consumption on plasma PON-1 activity and lipid profile in healthy nonobese subjects.Methods: Thirty-one subjects (body mass index [BMI] 24.4 ± 4.0 kg/m2) on their usual diet consumed 500 ...
Tópico(s): Pomegranate: compositions and health benefits
2016 - Taylor & Francis | Journal of the American College of Nutrition
Wioleta Łuszczek, Wioletta Kubicka, Monika Jasek, Emine Baran, M Cisło, Piotr Nockowski, M. Łuczywo‐Rudy, Andrzej Wiśniewski, Izabela Nowak, Piotr Kuśnierczyk,
Summary CTLA‐4 molecule is an important inhibitor of T‐lymphocyte activation. Several single nucleotide polymorphisms (SNPs) in the CTLA‐4 gene were found, and their associations with many human diseases were described. So far, however, such studies have not been performed in psoriasis vulgaris in Caucasoids. Therefore, we examined the distribution of three CTLA‐4 SNPs: −1147C/T, −318C/T and +49 A/G in 116 patients with psoriasis vulgaris and 123 healthy blood donors using the polymerase chain reaction– ...
Tópico(s): Immunodeficiency and Autoimmune Disorders
2006 - Wiley | International Journal of Immunogenetics
Piotr Kukla, Robert Długopolski, Ewa Krupa, Romana Furtak, Roman Szełemej, Ewa Mirek-Bryniarska, Marek Jastrzębski, Jacek Nowak, Piotr Wańczura, Leszek Bryniarski,
To assess the influence of electrocardiographic (ECG) pattern on prognosis and complications of patients hospitalized with acute pulmonary embolism (APE).We performed a retrospective analysis of 292 patients who had confirmed APE. There were 183 females and 109 males, the age range was 17 to 89 years, and the mean age was 65.4 ± 15.5 years.In our study group, there were 33 deaths (mortality rate, 11.3%), and 73 (25%) patients developed complications during hospitalization. Based on European Society of ...
Tópico(s): Acute Myocardial Infarction Research
2011 - Via Medica | Cardiology Journal
Błażej Nowak, Piotr Rogujski, Mirosław Janowski, Barbara Łukomska, A Andrzejewska,
Mesenchymal stem cells (MSCs) are among the most investigated and applied somatic stem cells in experimental therapies for the regeneration of damaged tissues. Moreover, as it was recently postulated, MSCs may demonstrate anti-tumor properties. Glioblastoma (GBM) is a grade IV central nervous system tumor with no available effective therapy and an inevitably fatal prognosis. Experimental studies utilizing MSCs in GBM treatment resulted in numerous controversies. Native MSCs were shown to exert anti- ...
Tópico(s): Glioma Diagnosis and Treatment
2021 - Elsevier BV | Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
Carlos Hidalgo, Myriam E. Vaca-Recalde, Mateusz Nowak, Piotr Frölich, Martin J. Reed, Mays Al-Naday, Asterios Mpatziakas, Aikaterini Protogerou, Anastasios Drosou, Dimitrios Tzovaras,
The increase in the safety and privacy of automated vehicle drivers against hazardous cyber-attacks will lead to a considerable reduction in the number of global deaths and injuries. In this sense, the European Commission has focused attention on the security of communications in high-risk systems when receiving a cyber-attack such as automated vehicles. The project SerIoT comes up as an possible solution, providing a useful open and reference framework for real-time monitoring of the traffic exchanged ...
Tópico(s): Traffic control and management
2021 - Elsevier BV | Vehicular Communications
Baptiste Bedessem, Bogna Gawrońska-Nowak, Piotr Lis,
We assess the relationship between citizens’ participation in scientific research and public trust in research results within social sciences. We conduct an online citizen science quasi-experiment concerning the delineation of metropolitan areas of Poland’s two major cities. It consists of two stages. In stage one, participants in one region are exposed to citizen science and directly involved in delineating the boundaries of their local metropolitan area. In stage two, we add another region in ...
Tópico(s): Plant and animal studies
2021 - UACES | Journal of Contemporary European Research
P. Rumianek, Tomasz Dobosz, Radosław Nowak, Piotr Dziewit, Andrzej Aromiński,
Closed-cell expanded polypropylene (EPP) foam is commonly used in car bumpers for the purpose of absorbing energy impacts. Characterization of the foam’s mechanical properties at varying strain rates is essential for selecting the proper material used as a protective structure in dynamic loading application. The aim of the study was to investigate the influence of loading strain rate, material density, and microstructure on compressive strength and energy absorption capacity for closed-cell polymeric ...
Tópico(s): Natural Fiber Reinforced Composites
2021 - Multidisciplinary Digital Publishing Institute | Materials
Błażej Nowak, Piotr Szymański, Igor Pańkowski, Agnieszka Szarowska, Katarzyna Życińska, Wojciech Rogowski, Robert Gil, Mariusz Furmanek, Jacek Tatur, Artur Zaczyński, Zbigniew Król, Waldemar Wierzba,
severe acute respiratory syndrome coronavirus 2 AbsTRACTINTROduCTION Since the first reported case of coronavirus disease 2019 (COVID -19) in Poland, the worldwide pandemic has spread throughout the country, leading to many hospital admissions.There has been an urgent need to determine clinical characteristics of Polish patients with laboratory -confirmed severe acute respiratory syndrome coronavirus 2 (SARS -CoV -2) infection in the clinical setting.ObjECTIvEs The aim of this retrospective study was ...
Tópico(s): Long-Term Effects of COVID-19
2020 - Medycyna Praktyczna | Polskie Archiwum Medycyny Wewnętrznej
A Andrzejewska, Sylwia Dabrowska, Błażej Nowak, Piotr Walczak, Barbara Łukomska, Mirosław Janowski,
Rationale:The groundbreaking discovery of mesenchymal stem cells (MSCs) with their multifaceted benefits led to their widespread application in experimental medicine, including neurology.Efficient delivery of MSCs to damaged regions of the central nervous system may be a critical factor in determining outcome.Integrin VLA-4 (α4β1) coded by ITGA4 and ITGB1 genes is an adhesion molecule expressed by leukocytes, which is responsible for initiation of their diapedesis through cell docking to the inflamed ...
Tópico(s): Tissue Engineering and Regenerative Medicine
2020 - Ivyspring International Publisher | Theranostics
Małgorzata Szczepanek, Grzegorz Lemańczyk, Robert Lamparski, Edward Wilczewski, Radomir Graczyk, Rafał Nowak, Piotr Prus,
Crop management should be determined to reintroduce ancient wheat. This study aimed to determine: i. the response of the yield of ancient wheat on sowing density; ii. the impact of sowing density on plant health, weed infestation and pest occurrence. Field experiments were carried out in Poland, on three organic farms. The factors were: (1) wheat species: Persian wheat (Triticum persicum Vav.) and Indian dwarf wheat (T. sphaerococcum Perc.), (2) sowing density (400, 500, and 600 grains m−2). Increasing ...
Tópico(s): Plant Pathogens and Resistance
2020 - Multidisciplinary Digital Publishing Institute | Agriculture
Marian Gorynia, Jan Nowak, Piotr Trąpczyński, Radosław Wolniak,
The purpose of the present study is to incorporate geographic analysis of FDI into the classic IDP model. By supplementing the traditional analysis of the net outward investment (NOI) position with an analysis of geographic patterns in inward and outward FDI, the authors strive to offer a better explanation of Poland's current NOI position and provide more in-depth support to some necessary policy recommendations. Hence the main contribution of this study to the international business scholarship ...
Tópico(s): Global Trade and Competitiveness
2019 - Taylor & Francis | Post-Communist Economies
Artur Juszkiewicz, Aleksandra Glapa-Nowak, Piotr Basta, Elżbieta Petriczko, K. Żołnowski, Bogusław Machaliński, Jerzy Trzeciak, Karolina Łuczkowska, Anna Skarpańska-Stejnborn,
Background The aim of this study was to analyze the response of selected components of the immune system in rowers to maximal physical exercise, and to verify if this response could be modulated by supplementation with L-theanine. Method The double-blind study included 20 members of the Polish Rowing Team. The subjects were randomly assigned to the supplemented group (n = 10), receiving 150 mg of L-theanine extract for 6 weeks, or to the placebo group (n = 10). The participants performed a 2000-m test ...
Tópico(s): Herbal Medicine Research Studies
2019 - Springer Science+Business Media | Journal of the International Society of Sports Nutrition
Andrzej Wiśniewski, Łukasz Matusiak, Aneta Szczerkowska‐Dobosz, Izabela Nowak, Piotr Kuśnierczyk,
Psoriasis vulgaris (PsV) is a common, chronic skin disease with a complex genetic and environmental etiology. We investigated, in 461 psoriatic patients and 454 healthy controls, the associations with psoriasis of four single-nucleotide polymorphisms (SNPs) from the psoriasis susceptibility 1 (PSORS1) interval: rs1062470 (PSORS1C1/CDSN), rs887466 (PSORS1C3), rs2894207 and rs10484554 (LOC105375015). The minor alleles of three SNPs (rs1062470A, rs2894207C and rs10484554T) strongly increased the disease risk ( ...
Tópico(s): Asthma and respiratory diseases
2018 - Springer Science+Business Media | Molecular Genetics and Genomics
Jacek Antonkiewicz, Agnieszka Baran, Robert Pełka, Anna Wisła-Świder, Ewelina Nowak, Piotr Konieczka,
Chemical contaminants present in cellulose production waste and municipal sewage sludge condition the necessity to treat these wastes before they are introduced into the environment. Environmental use of the these wastes appears to be justified owing to the content of organic substances as well as the considerable fertilising value. The aim of the study was to assess chemical composition and ecotoxicity of cellulose production waste and municipal sewage sludge in terms of their eco-friendly application. ...
Tópico(s): Adsorption and biosorption for pollutant removal
2018 - Elsevier BV | Ecotoxicology and Environmental Safety
Marian Gorynia, Jan Nowak, Piotr Trąpczyński, Radosław Wolniak,
Many existing studies on emerging markets and firms have concentrated on the separate effects of institutional reforms and quality of the institutional infrastructure for attracting inward foreign direct investment (FDI) and fostering outward FDI. We argue that both these perspectives should be considered in an interplay, as there are links between inward and outward FDI in a country's economic development, which is captured by the investment development path (IDP) concept. Moreover, while predominant ...
Tópico(s): Regional Development and Policy
2018 - Elsevier BV | International Business Review
Elizabeth M. Carnicom, Judyta Strychalska‐Nowak, Piotr Wiśniewski, D. Kaczorowski, Weiwei Xie, Tomasz Klimczuk, R. J. Cava,
We show that the superhard boride WB$_{4.2}$ is a superconductor with a T$_c$ of 2.05(5) K. Temperature-dependent magnetic susceptibility, electrical resistivity, and specific heat measurements were used to characterize the superconducting transition. The Sommerfeld constant {\gamma} for WB$_{4.2}$ is 2.07(3) mJ mol$^{-1}$ K$^{-2}$ and the {\Delta}C/{\gamma}T$_c$ = 1.56, which is somewhat higher than what is expected for weakly coupled BCS type superconductors. The H$_{c2}$ vs T plot is linear over a ...
Tópico(s): Iron-based superconductors research
2018 - IOP Publishing | Superconductor Science and Technology
Aleksandra Solińska-Nowak, Piotr Magnuszewski, Margot Curl, Adam French, Adriana Keating, Junko Mochizuki, Wei Liu, Reinhard Mechler, Michalina Kułakowska, Łukasz Jarząbek,
This paper reviews serious games/simulations addressing issues related to disaster risk management (DRM) and serving as educational and engagement tools for affected communities, policy-makers, and other stakeholders. Building on earlier research in collecting and classifying serious games, we provide an objective and thorough overview of 45 non-commercial digital and analog gaming activities related to DRM, analyzing their characteristics, target groups, portrayed hazards, and possible DRM skills ...
Tópico(s): Disaster Management and Resilience
2018 - Elsevier BV | International Journal of Disaster Risk Reduction
Urszula Doboszewska, Katarzyna Młyniec, Aleksandra Właź, Ewa Poleszak, Gabriel Nowak, Piotr Właź,
Evidence from both preclinical and clinical studies suggest the importance of zinc homeostasis in seizures/epilepsy. Undoubtedly, zinc, via modulation of a variety of targets, is necessary for maintaining the balance between neuronal excitation and inhibition, while an imbalance between excitation and inhibition underlies seizures. However, the relationship between zinc signaling and seizures/epilepsy is complex as both extracellular and intracellular zinc may produce either protective or detrimental ...
Tópico(s): Epilepsy research and treatment
2018 - Elsevier BV | Pharmacology & Therapeutics
Ewa Grela, Miłosz Wieczór, Rafał Luchowski, Joanna Zielińska, Angelika Barzycka, Wojciech Grudziński, Katarzyna Nowak, Piotr Tarkowski, Jacek Czub, Wiesław I. Gruszecki,
Amphotericin B is a lifesaving polyene antibiotic used in the treatment of systemic mycoses. Unfortunately, the pharmacological applicability of this drug is limited because of its severe toxic side effects. At the same time, the lack of a well-defined mechanism of selectivity hampers the efforts to rationally design safer derivatives. As the drug primarily targets the biomembranes of both fungi and humans, new insights into the binding of amphotericin B to lipid membranes can be helpful in unveiling ...
Tópico(s): Spectroscopy and Quantum Chemical Studies
2018 - American Chemical Society | Molecular Pharmaceutics
Jarosław Suchański, Jędrzej Grzegrzółka, Tomasz B. Owczarek, Paweł Pasikowski, Aleksandra Piotrowska, Bartłomiej Kocbach, Aleksandra Nowak, Piotr Dzięgiel, Andrzej Wojnar, Maciej Ugorski,
We have previously shown that galactosylceramide (GalCer) affects the tumourigenic and metastatic properties of breast cancer cells by acting as an anti-apoptotic molecule. Since GalCer is a precursor molecule in the synthesis of sulfatides, the present study was aimed to define the role of sulfatides in apoptosis and breast cancer progression. Expression of GAL3ST1 in breast cancer cell lines and breast cancer tissue specimens was analysed using real-time PCR, western blotting and immunohistochemistry ...
Tópico(s): Sphingolipid Metabolism and Signaling
2018 - BioMed Central | Breast Cancer Research
Marlena Robakowska, Daniel Ślęzak, Anna Tyrańska-Fobke, Joanna Nowak, Piotr Robakowski, Przemysław Żuratyński, Jerzy Robert Ładny, Klaudiusz Nadolny,
The implementation of drones in the medical security system requires a proper planning of the cooperation of different services, dividing the area into sectors, assessing potential risks, and other factors. This study refers to the cost analysis of using drones in the medical support of mass events. The aim of this research is to analyze the costs of unmanned aerial vehicle (UAV) implementation in the mass event medical support system.The description includes purchase and maintenance costs of UAVs. ...
Tópico(s): Insurance and Financial Risk Management
2018 - Cambridge University Press | Disaster Medicine and Public Health Preparedness