Produção Nacional
Revisado por pares
Sarah de Sousa Ferreira, Diana Pontes da Silva, Manoela Torres-Rêgo, Arnóbio Antônio da Silva-Júnior, Matheus de Freitas Fernandes‐Pedrosa,
Ophidism is a serious health problem worldwide and is included in the World Health Organization's (WHO's) list of Neglected Tropical Diseases. Although snakebite envenoming requires emergency treatment, currently the only treatment recommended by WHO is serotherapy, which has some disadvantages such as low access to the rural population, low effectiveness in neutralizing local effects, and high cost. In this context, new alternatives for the treatment of snakebites are required. The use of plant- ...
Tópico(s): Insect and Pesticide Research
2021 - Elsevier BV | Toxicon
Produção Nacional
Revisado por pares
Machado Yguatyara de Luna, Ponte Marcelo Rodrigues, Gadelha Antônia Mabrysa Torres, da Costa Júnior Antônio Eufrázio, Malveira Jackson Queiroz, Mazzetto Selma Elaine, Maria Alexsandra de Sousa Rios,
In this study, the energy potential of five types of biomass waste from cultures of banana (Musa spp.), cashew (Anacardium occidentale L.), babassu coconut (Orbignya speciosa), mango (Mangifera indica), and several flowers from the central hinterland of Ceará, Brazil was evaluated, to investigate their applicability as potential sources of alternative energy, for example, Briquettes. Many countries have been looking for new types of energy that are sustainable and clean, and biomass energy has been ...
Tópico(s): Forest Biomass Utilization and Management
2018 - Taylor & Francis | Energy Sources Part A Recovery Utilization and Environmental Effects
Produção Nacional
Revisado por pares
Mara Alves da Cruz Gouveia, Manuela Torres Camara Lins, Giselia Alves Pontes da Silva,
To restate the epidemiological importance of Shigella in acute diarrhea with blood, providing an overview of the treatment and stressing the need for the correct indication of antibiotic therapy. A search was carried out in the Medline and Scopus databases, in addition to the World Health Organization scientific documents and guidelines, identifying review articles and original articles considered relevant to substantiate the narrative review. Different pathogens have been associated with acute ...
Tópico(s): Escherichia coli research studies
2019 - Elsevier BV | Jornal de Pediatria
Gabriela Ribeiro, Marta Camacho, Osvaldo Santos, Cristina Pontes, Sandra Torres, Albino J. Oliveira‐Maia,
Obesity-associated differences in hedonic hunger, while consistently reported, have not been adequately quantified, with most studies failing to demonstrate strong correlations between Body Mass Index (BMI) and hedonic hunger indicators. Here, we quantified and assessed the nature of the relationship between hedonic hunger and BMI, in a cross-sectional study using the Portuguese version of the PFS (P-PFS) to measure hedonic hunger. Data were collected from 1266 participants belonging to non-clinical, ...
Tópico(s): Bariatric Surgery and Outcomes
2018 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Paloma Leão Sousa, Yves Quinet, Edson Lopes da Ponte, Jaqueline F. do Vale, Alba Torres, Maria Gonçalves Pereira, Ana Maria Sampaio Assreuy,
In northeastern Brazil, Dinoponera (Ponerinae) ants macerate are used to treat ear ache and its sting, rheumatism, and back pain. Such a popular use is a relevant fact that called for experimental evaluation of the antinociceptive activity of Dinoponera venom. Dinoponera quadriceps venom (DqV; 5–500 μg/kg; i.v.) or morphine (3.4 mg/kg; s.c.) were evaluated in mice models of nociception (n=8 animals/group). Negative controls received sterile saline (0.9% NaCl; i.v.). DqV showed 64% protein content and ...
Tópico(s): Insect and Arachnid Ecology and Behavior
2012 - Elsevier BV | Journal of Ethnopharmacology
José Ríos, Joaquín Sáez‐Peñataro, Caridad Pontes, Ferrán Torres,
Abstract Randomized clinical trials are the gold standard when experimental designs are feasible. Randomization allows the handling of allocation bias for known and unknown confounders. Specific tools such as blocking, stratification, and dynamic allocation provide additional guarantees to simple randomization. When an experimental design is not feasible, the propensity score (PS) has been shown to produce greater benefit than traditional methods (i.e., restriction, stratification, matching and adjusting). ...
Tópico(s): Health Systems, Economic Evaluations, Quality of Life
2017 - Thieme Medical Publishers (Germany) | Seminars in Liver Disease
Marta Ulldemolins, Ignacio Martín‐Loeches, Mireia Llauradó‐Serra, Javier Fernández, Sergi Vaquer, Alejandro Rodríguez, Caridad Pontes, Gonzalo Calvo, Antoni Torres, Dolors Soy,
This multicentre study aimed to describe the pharmacokinetics (PK) of piperacillin in critically ill patients with multiple organ dysfunction syndrome (MODS) receiving continuous venovenous haemodiafiltration (CVVHDF), to identify the sources of PK variability and evaluate different dosing regimens to develop recommendations based on clinical parameters. Nineteen patients with MODS and CVVHDF receiving piperacillin/tazobactam were enrolled from three tertiary hospitals (95 plasma samples). Population ...
Tópico(s): Nosocomial Infections in ICU
2016 - Oxford University Press | Journal of Antimicrobial Chemotherapy
Produção Nacional
Monique Maria Silva da Paz, Raquel de Moura Campos Diniz, Milene de Oliveira Almeida, Nadine Oliveira Cabral, Thais Josy Castro Freire de Assis, Milleny Fernandes de Sena, Viviann Alves de Pontes, Natália Mota da Silva Borges, Cristina Kátya Torres Teixeira Mendes,
Abstract Objectives: to analyze the level of anxiety in high risk pregnant women admitted in the maternity ward of the Hospital Universitário Lauro Wanderley (HULW) of the Federal University of Paraíba. Methods: an observational, descriptive, cross-sectional study of quantitative character, with a sample composed of 100 pregnant women diagnosed as high risk interned at HULW. Data collection was performed using the Beck Anxiety Inventory (BAI), used to assess the level of anxiety the patient is in ...
Tópico(s): Attachment and Relationship Dynamics
2022 - Instituto Materno Infantil de Pernambuco | Revista Brasileira de Saúde Materno Infantil
Francisco García Soriano, Carmen Ponte, Manuel Santamarı́a, A. Torres, R. Fernández‐Roblas,
The susceptibility in vitro of 28 Corynebacterium group D2 strains, mainly isolated from urine, to fifteen antimicrobial agents and acetohydroxamic acid (AHA) was determined at two pH values. The bactericidal activity of four antimicrobials and AHA was studied in three reference strains in broth at two pHs and with two inoculum sizes. The activity of norfloxacin and AHA, against one selected strain, in broth and human urine, was also determined. Vancomycin, ofloxacin and norfloxacin were the most ...
Tópico(s): Clostridium difficile and Clostridium perfringens research
1987 - Oxford University Press | Journal of Antimicrobial Chemotherapy
Marta Ulldemolins, Dolors Soy, Mireia Llauradó‐Serra, Sergi Vaquer, Pedro Castro, Alejandro Rodríguez, Caridad Pontes, Gonzalo Calvo, Antoní Torres, Ignacio Martín‐Loeches,
ABSTRACT Meropenem dosing in critically ill patients with septic shock and continuous renal replacement therapy (CRRT) is complex, with the recommended maintenance doses being 500 mg to 1,000 mg every 8 h (q8h) to every 12 h. This multicenter study aimed to describe the pharmacokinetics (PKs) of meropenem in this population to identify the sources of PK variability and to evaluate different dosing regimens to develop recommendations based on clinical parameters. Thirty patients with septic shock and ...
Tópico(s): Poisoning and overdose treatments
2015 - American Society for Microbiology | Antimicrobial Agents and Chemotherapy
Produção Nacional
Revisado por pares
Diana Pontes da Silva, Sarah de Sousa Ferreira, Manoela Torres-Rêgo, Allanny Alves Furtado, Fabiana De Oliveira Yamashita, Eduardo Augusto da Silva Diniz, Davi Serradella Vieira, Marcela Abbott Galvão Ururahy, Arnóbio Antônio da Silva-Júnior, Karla Patrícia de Oliveira Luna, Matheus de Freitas Fernandes‐Pedrosa,
Bothrops leucurus is responsible for most cases of snakebite in Northeast Brazil; however, this species is not included in the pool of venoms used in antivenom production in Brazil. The serotherapy has logistical and effectiveness limitations, which stimulates the search for therapeutic alternatives. Chlorogenic acid and rosmarinic acid present several biological activities, but their antiophidic potential has been poorly explored. Thus, the aim of this approach was to evaluate the potential inhibitory ...
Tópico(s): Bioactive Natural Diterpenoids Research
2022 - Elsevier BV | Biomedicine & Pharmacotherapy
Produção Nacional
Revisado por pares
Glácio Souza Araújo, Wladimir Ronald Lobo Farias, José Ariévilo Gurgel Rodrigues, Valeska Martins Torres, Grazielle da Costa Pontes,
Resumo – Diversos agentes imunoestimulantes tem sido estudados visando minimizar o impacto do estresse em cultivos intensivos de organismos aquaticos, dentre eles os polissacarideos sulfatados (PS) de algas marinhas. Objetivou-se avaliar o efeito da administracao oral de PS, extraidos da alga marinha vermelha Gracilaria caudata, na sobrevivencia e ganho de peso de pos-larvas (pl) da tilapia do Nilo, Oreochromis niloticus, durante a fase de reversao sexual. Os PS foram incorporados a racao dos peixes ...
Tópico(s): Invertebrate Immune Response Mechanisms
2008 - UNIVERSIDADE FEDERAL DO CEARÁ | Ciência Agronômica/Revista ciência agronômica
Mercedes Pallero, Carme Puy, Rosa Güell, Caridad Pontes, Sergi Martí, Ferrán Torres, Antonio Antón, Xavier Muñoz,
BackgroundHome mechanical ventilation is usually initiated in hospital. However, cost-effectiveness of inpatient set up has never been compared to outpatient adaptation in a randomized design. A Prospective, multicenter, non-inferiority trial was conducted comparing the effectiveness of adaptation to noninvasive mechanical ventilation (NIMV) performed in the ambulatory or hospital setting in patients with chronic respiratory failure secondary to restrictive thoracic disease, obesity-hypoventilation ...
Tópico(s): Family and Patient Care in Intensive Care Units
2014 - Elsevier BV | Respiratory Medicine
Produção Nacional
Revisado por pares
Neuber Martins Fonseca, Gabriel Magalhães Nunes Guimarães, João Paulo Jordão Pontes, Liana Maria Tôrres de Araújo Azi, Ricardo de Ávila Oliveira,
Spinal infusions of either fentanyl or sufentanil have been reported in international reports, articles, and scientific events worldwide. This study aimed to determine whether intrathecal fentanyl or sufentanil offers safety in mortality and perioperative adverse events. MEDLINE (via PubMed), EMBASE, CENTRAL (Cochrane library databases), gray literature, hand-searching, and clinicaltrials.gov were systematically searched. Randomized controlled trials with no language, data, or status restrictions ...
Tópico(s): Anesthesia and Sedative Agents
2021 - Elsevier BV | Brazilian Journal of Anesthesiology (English Edition)
Produção Nacional
Marla Geórgia Monteiro Barros, Michelle Caroline da Silva Santos, Raphaella Patrícia Torres Bertolini, Valderlane Bezerra Pontes Netto, Maria Sandra Andrade,
OBJECTIVE: to describe aspects related to missed vaccination opportunities at Primary Health Care Units at Health District II, in Recife, Pernambuco, Brazil. METHODS: this was a descriptive study aimed at children under 1 year of age with delayed vaccination in 2012; data were collected by applying structured forms and an interview with parents or guardians. RESULTS: 18 Primary Health Care Units and 33 vaccinators were evaluated. 300 vaccination record cards were analyzed, 120 (40%) of which were ...
Tópico(s): Ethics and Legal Issues in Pediatric Healthcare
2015 - MINISTÉRIO DA SAÚDE | Epidemiologia e Serviços de Saúde
Produção Nacional
Revisado por pares
Naína Yuki Vieira Jardim, Natáli Valím Oliver Bento-Torres, Victor Oliveira da Costa, Josilayne Patrícia Ramos Carvalho, Helen Tatiane Santos Pontes, Alessandra Mendonça Tomás, Márcia Consentino Kronka Sosthenes, Kirk I. Erickson, João Bento‐Torres, Cristovam Wanderley Picanço Diniz,
Background It has been suggested that physical inactivity and lack of stimulating cognitive activity are the two most significant modifiable risk factors to impair cognitive function. Although many studies that investigated the cognitive effects of physical exercise and cognitive stimuli in dual-task conditions showed improved cognitive performance, others have not confirmed these findings. The main aim of the present work is to analyze the effects of a dual-task multimodal physical exercise training, ...
Tópico(s): Balance, Gait, and Falls Prevention
2021 - Frontiers Media | Frontiers in Aging Neuroscience
Produção Nacional
Revisado por pares
Sérgio Augusto Lopes de Souza, Léa Mirian Barbosa da Fonseca, Renato Torres Gonçalves, Daniela Ferreira Salomão Pontes, Tatjana Holzer, Flávia Paiva Proença Martins, Bianca Gutfilen,
One hundred kidney transplant recipients were evaluated on the first and fifth days after transplantation by Tc-99m mononuclear cell scintigraphy. We have developed a quantitative method to diagnose rejection and acute tubular necrosis (ATN) by comparing regions of interest drawn on allograft scintigraphs at different times after endovenous administration of the labeled cells. We suggest that the use of Tc-99m-WBC may be useful for the early diagnosis of rejection and the differential diagnosis of ...
Tópico(s): Renal Transplantation Outcomes and Treatments
2004 - Elsevier BV | Transplantation Proceedings
Produção Nacional
Revisado por pares
Marcelo Victor Holanda Moura, Giulia Pontes da Silva, Antônio Carlos de Oliveira Machado, Fernando Araripe Gonçalves Torres, Denise Maria Guimarães Freire, Rodrigo Volcan Almeida,
Yeast Surface Display (YSD) is a strategy to anchor proteins on the yeast cell wall which has been employed to increase enzyme stability thus decreasing production costs. Lipase B from Candida antarctica (LipB) is one of the most studied enzymes in the context of industrial biotechnology. This study aimed to assess the biochemical features of this important biocatalyst when immobilized on the cell surface of the methylotrophic yeast Pichia pastoris using the YSD approach. For that purpose, two anchors ...
Tópico(s): Fungal and yeast genetics research
2015 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Alberto Torres, Renato B. Pontes, Antônio J. R. da Silva, A. Fazzio,
We theoretically investigate, as a function of the stretching, the behaviour of the Seebeck coefficient, the electronic heat conductance and the figure of merit of a molecule-based junction composed of a benzene-1,4-dithiolate (BDT) molecule coupled to Au(111) surfaces at room temperature.
Tópico(s): Force Microscopy Techniques and Applications
2015 - Royal Society of Chemistry | Physical Chemistry Chemical Physics
Inmaculada Tasset, A J Pontes, Ashlin J. Hinojosa, Rafael de la Torre, Isaac Túnez,
Free radicals contribute to altered neuronal functions in neurodegenerative diseases and brain aging, by producing lipid- and other molecule-dependent modifications. The Mediterranean diet has been associated with a reduced risk of neurodegenerative disease. This study sought to verify whether extra-virgin olive oil (EVOO) exerted a brain antioxidant effect, protecting the brain against the oxidative stress caused by 3-nitropropionic acid (3NP). 3NP was administered intraperitoneally (i.p.) at a dose ...
Tópico(s): Edible Oils Quality and Analysis
2011 - Taylor & Francis | Nutritional Neuroscience
Produção Nacional
Revisado por pares
Elvys Linhares Pontes, Stéphane Huet, Juan‐Manuel Torres‐Moreno, Andréa Carneiro Linhares,
The popularization of social networks and digital documents has quickly increased the multilingual information available on the Internet. However, this huge amount of data cannot be analyzed manually. This paper deals with Cross-Language Text Summarization (CLTS) that produces a summary in a different language from the source documents. We describe three compressive CLTS approaches that analyze the text in the source and target languages to compute the relevance of sentences. Our systems compress ...
Tópico(s): Algorithms and Data Compression
2019 - Elsevier BV | Data & Knowledge Engineering
Produção Nacional
Revisado por pares
Paula Torres da Silva, Suely Master, Solange Andreoni, Paulo Pontes, Luiz Roberto Ramos,
Tópico(s): Phonetics and Phonology Research
2010 - Elsevier BV | Journal of Voice
Produção Nacional
Revisado por pares
Elvys Linhares Pontes, Stéphane Huet, Juan‐Manuel Torres‐Moreno, Andréa Carneiro Linhares,
Cross-Language Automatic Text Summarization produces a summary in a language different from the language of the source documents. In this paper, we propose a French-to-English cross-lingual summarization framework that analyzes the information in both languages to identify the most relevant sentences. In order to generate more informative cross-lingual summaries, we introduce the use of chunks and two compression methods at the sentence and multi-sentence levels. Experimental results on the MultiLing ...
Tópico(s): Advanced Text Analysis Techniques
2018 - Springer Science+Business Media | Lecture notes in computer science
Produção Nacional
Revisado por pares
Priscila Vieira Pontes, Alexandre Guedes Torres, Nádia M.F. Trugo, Vânia Matos Fonseca, Rosely Sichieri,
Placental transfer of the long-chain polyunsaturated fatty acids (LCPUFA) arachidonic (AA) and docosahexaenoic (DHA) acids is selectively high to maintain accretion to fetal tissues, especially the brain. The objectives of the present study were to investigate the essential fatty acid (EFA) and LCPUFA status at birth of preterm and term Brazilian infants and their mothers, from a population of characteristically low intake of n-3 LCPUFA, and to evaluate the association between fetal and maternal status, ...
Tópico(s): Neuroscience of respiration and sleep
2005 - Elsevier BV | Prostaglandins Leukotrienes and Essential Fatty Acids
Produção Nacional
Revisado por pares
Karine Scanci da Silva Pontes, Márcia Regina Simas Torres Klein, Mariana Silva da Costa, Kelli Trindade de Carvalho Rosina, Ana Paula Medeiros Menna Barreto, Maria Inês Barreto Silva, Suzimar Rioja,
Abstract The aim of the present study was to evaluate the prevalence of vitamin B 12 (B 12 ) deficiency in kidney transplant recipients (KTR) and its possible association with B 12 dietary intake, body adiposity and immunosuppressive drugs. In this cross-sectional study, we included 225 KTR, aged 47·50 ( sd 12·11) years, and 125 (56 %) were men. Serum levels of B 12 were determined by chemiluminescent microparticle intrinsic factor assay and the cut-off of 200 pg/ml was used to stratify KTR into B 12 -sufficient ...
Tópico(s): Pharmacological Effects and Toxicity Studies
2019 - Cambridge University Press | British Journal Of Nutrition
Caridad Pontes, Roser Vives, Ferrán Torres, Julián Panés,
Dersalazine sodium is an inhibitor of platelet activator factor with potential efficacy in patients with ulcerative colitis through an alternative mechanism of action. The study was a first proof of clinical safety and activity of dersalazine sodium in patients with ulcerative colitis. A double-blind study of randomized patients with ulcerative colitis (Mayo score ≥5 and ≤10, including a sigmoidoscopy subscore ≥2) to dersalazine sodium 1200 mg/12 h, mesalazine 1200 mg/12 h, or placebo for 4 weeks. Mayo ...
Tópico(s): Microscopic Colitis
2014 - Oxford University Press | Inflammatory Bowel Diseases
Produção Nacional
Revisado por pares
Juliana Souza de Pontes, Fritz Oehl, Cícero Donizete Pereira, Cynthia Torres de Toledo Machado, Danny Coyne, Danielle Karla Alves da Silva, Leonor Costa Maia,
The Cerrado is the largest savanna biome in the Neotropics and considered a major hotspot for world biodiversity. However, over recent decades the area has increasingly been converted to intensive agricultural ecosystems, primarily for soybean production. Conservation tillage systems have gained major importance in tropical America, especially in the Brazilian Cerrado. Long-term field experiments were established to evaluate the effects of soil tillage on soybean production in the Cerrado. The aim ...
Tópico(s): Ecology and Vegetation Dynamics Studies
2017 - Elsevier BV | Applied Soil Ecology
Produção Nacional
Revisado por pares
Rose Meire Albuquerque Pontes, Sender Jankiel Miszputen, Olavo Franco Ferreira-Filho, Cláudio Torres de Miranda, Marcos Bosi Ferraz,
Crohn's disease comprises, together with ulcerative colitis, the inflammatory bowel diseases, which because their morbidity and chronic evolution have a considerable impact on the patient's quality of life. The measurement of quality of life requires the determination of the degree of subjective well-being attributed to the lack of symptoms, to psychological state and daily activity, and is useful as an instrument of evaluation, both in clinical trials and health programs. Inflammatory Bowel Disease ...
Tópico(s): Eosinophilic Esophagitis
2004 - Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE) | Arquivos de Gastroenterologia
Produção Nacional
Revisado por pares
Rita de Cássia Coelho Moraes de Brito, Norma Lucena‐Silva, Leuridan Cavalcante Torres, Carlos Feitosa Luna, Jailson B. Correia, Giselia Alves Pontes da Silva,
To identify markers for earlier diagnosis of severe pneumonia, we assess the correlation between serum cytokine profile of children with different pneumonia severity. In 25 hospitalized children, 7 with mild pneumonia and 18 with severe pneumonia, the serum concentration of 11 cytokines in three sampling times were dosed. Statistical analysis included parametric and non-parametric tests, Pearson correlation and ROC curve for cut-off definition of cytokines. At admission, IL-6 serum levels were high ...
Tópico(s): Sepsis Diagnosis and Treatment
2016 - BioMed Central | BMC Pulmonary Medicine
Produção Nacional
Revisado por pares
Sílvia Amoretti, Francisco Diego Rabelo-da-Ponte, Adriane Ribeiro Rosa, Gisela Mezquida, Ana M. Sánchez-Torres, David Fraguas, Bibiana Cabrera, António Lobo, Ana González‐Pinto, Laura Pina‐Camacho, Iluminada Corripio, Eduard Vieta, Carla Torrent, Elena de la Serna, Daniel Bergé, Miquel Bioque, Marina Garriga, Maria Serra‐Navarro, Manuel J. Cuesta, Miquel Bernardo,
Impairments in a broad range of cognitive domains have been consistently reported in some individuals with first-episode psychosis (FEP). Cognitive deficits can be observed during the prodromal stage. However, the course of cognitive deficits is still unclear. The aim of this study was to identify cognitive subgroups over time and to compare their sociodemographic, clinical and functional profiles. A total of 114 patients with Schizophrenia Spectrum Disorders were included in the present study. We ...
Tópico(s): Neuroscience and Music Perception
2021 - Elsevier BV | Schizophrenia Research