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Imagens Acesso aberto

Wellcome Library, London. Series: Iconographic Collections. Photographer: John Thomson.

0000 - Gale Group | NCCO Photography

Artigo Acesso aberto Revisado por pares

Massimo Merighi, Alecia N. Septer, Amanda Carroll‐Portillo, Aditi Bhatiya, Steffen Porwollik, Michael McClelland, John S. Gunn,

Abstract Background The Salmonella PreA/PreB two-component system (TCS) is an ortholog of the QseBC TCS of Escherichia coli . In both Salmonella and E. ... important virulence-associated TCS. Results To determine the PreA/PreB regulon in S . Typhimurium, we performed DNA microarrays comparing the wild type strain and various preA and/or preB mutants in the presence of ectopically expressed preA ( qseB ). These data confirmed our previous findings of the negative effect of PreB on PreA gene regulation and identified candidate PreA-regulated genes. ...

Tópico(s): Vibrio bacteria research studies

2009 - BioMed Central | BMC Microbiology

Imagens Acesso aberto

Wellcome Library, London. Glass ca. 25.5 cm x 20.5 cm (10 in. x 8 in.). Series: Iconographic Collections. Photographer: John Thomson.

0000 - Gale Group | NCCO Photography

Artigo Acesso aberto Revisado por pares

Michael L. Christensen,

... Children Act (BPCA) and Pediatric Research Equity Act (PREA) are companion legislation acts that together have resulted ... in neonates, infants, children, and adolescents.BPCA and PREA are set to expire October 1, 2012, and ... in children. In March 2012, the BPCA and PREA Reauthorization Act of 2012 was introduced; this Bill ... Children,3 which advocates making the BPCA and PREA laws permanent. The requirement that the bills be ... Institutes of Health to study "off-patent" drugs. PREA, first enacted in 2003, gives the FDA the ...

Tópico(s): Child and Adolescent Health

2012 - | The Journal of Pediatric Pharmacology and Therapeutics

Documentos governamentais Acesso aberto

Henry H. Stebbine, Pastor Grace (Prea.) Ch.,

Letters: Henry H. Stebbine, Pastor Grace (Prea.) Ch.; February 25, 1878; New York.

1878 - Gale Group | SAS Part 1

Artigo Acesso aberto Revisado por pares

Jason R. Wiles, Alexander A. Vinks, Henry T. Akinbi,

... Act (BPCA), and the Pediatric Research Equity Act (PREA).11US Congress Food and Drug Administration Modernization Act ... Future of pediatric therapeutics: reauthorization of BPCA and PREA.Clin Pharmacol Ther. 2007; 81: 477-479Crossref PubMed ... 29, 2011.Google Scholar Unlike the BPCA, the PREA, enacted in 2003, requires pediatric studies for the ... approval in adults.The FDAMA, BCPA, and the PREA have been credited with >400 pediatric drug-labeling ... of these studies. The reauthorization of BPCA and PREA provides an opportunity for the FDA to improve ...

Tópico(s): Pharmaceutical Economics and Policy

2012 - Elsevier BV | The Journal of Pediatrics

Artigo Acesso aberto Revisado por pares

Massimo Merighi, Amanda Carroll‐Portillo, Alecia N. Septer, Aditi Bhatiya, John S. Gunn,

... the identification of a two-component system, termed PreA/PreB (pmrCAB regulators A and B), that controls ... deletion of, the preB sensor, but not the preA response regulator, caused upregulation of pmrCAB. Interestingly, the ... a preAB mutant grown in LB broth, implicating PreA in the increased expression of pmrCAB in the preB strain. This was confirmed by overexpression of preA(+) in preAB or preB backgrounds, which resulted in ... preB(+) backgrounds. Additionally, an ectopic construct expressing a preA[D51A] allele also failed to upregulate pmrC in ...

Tópico(s): Vibrio bacteria research studies

2005 - American Society for Microbiology | Journal of Bacteriology

Jornais Acesso aberto

Colonel Dogey, L. Van Vliet Edited, Frank Rutter, L. T. Grein, L. R., J. T. Grein,

... Laundry The Secrets of Beauty To-Day's Prea Hers Forthcoming Events By "Strategos": With the Colours ...

1907 - Gale Group | Sunday Times HA GDA

Editorial Acesso aberto Revisado por pares

Miriam B. Vos, Lara Dimick‐Santos, Ruby Mehta, Stephanie O. Omokaro, Johannes Taminiau, Elmer Schabel, David E. Kleiner, Peter Szitányi, Piotr Socha, Jeffrey B. Schwimmer, Stephanie Noviello, Debra G. Silberg, Richard Torstenson, Veronica Miller, Joel E. Lavine, Nathalie Adda, William Baldyga, Rajarshi Banerjee, Cynthia Behling, Sherif Boulos, Gary Burgess, Dania Calboli, Edgar D. Charles, Rose Christian, Claude Cohen‐Bacrie, Doina Cosma-Roman, Claus-Peter Danzer, I. Delaet, Mark H. DeLegge, Lara Dimick‐Santos, Nicholas DiProspero, Kathleen Donohue, Laurent Fischer, Emer Fitzpatrick, Michael Fried, David Hagerty, Paula M. Hale, Keri Hildick, Dean W. Hum, Khurram Jamil, Lijuan Jiang, Saul J. Karpen, Matt Kelly, David E. Kleiner, Rohit Kohli, Kattayoun Kordy, Nancy Krieger, Joel E. Lavine, Lois K. Lee, Éric Lefebvre, Patricia López, Erica Lyons, Laura Malahias, S. Megnien, Ruby Mehta, Peter Mesenbrink, Veronica Miller, Pansy Minnick, Christine Murray, Tien Nghiem, Nikki Nicholson, Stephanie Noviello, Stephanie O. Omokaro, Wenjie Pang, Lisa Percival, Dan Peres, Margaret Powell, D.A. De Luis Román, Mark Root, Claire Sampson, Arun J. Sanyal, Elmer Schabel, Kathleen B. Schwarz, Jeffrey B. Schwimmer, Star Seyedkazemi, David E. Shapiro, Reshma Shringarpure, Debra G. Silberg, Edward R. Smith, Piotr Socha, Robert R. Squires, Peter Szitányi, Johannes Taminiau, Richard Torstenson, William R. Treem, Pamela Vig, Miriam B. Vos, Mason Yamashita, Michael B. Zemel,

... congress has enacted the Pediatric Research Equity Act (PREA) and Best Pharmaceuticals for Children Act (BPCA) that ... development of safe and efficacious drugs in children. PREA requires all applications submitted to FDA under section ... agreed-upon by FDA's Pediatric Review Committee. PREA applies to drugs or biological products developed for ... for pediatric-specific indications are subject to the PREA requirement only if they are initially developed for a subset of the relevant pediatric population. PREA does not apply to drugs that have been ...

Tópico(s): Diet, Metabolism, and Disease

2019 - Elsevier BV | Gastroenterology

Jornais Acesso aberto

Charles Freeman, Sec, M. R. D., W. C. N., J. D., J. C. H., Harriet N. Torrey, Amos Gilbert, H. M. P., National Era, Milton, John S. Slingerland, Everett's Address, W. P. Russell, Prea, Daivd C. Fuller, Sec., Boston Whig,

Miscellaneous: The NORTH STAR is published every Friday, at No.25, Buffalo Street, (Opposite the Arcade). News: Communications Extract from a Sermon, Rev. ...

1848 - Gale Group | SAS Part 1

Artigo Revisado por pares

Hayden P. Smith,

The Prison Rape Elimination Act (PREA) was created to address sexual violence occurring in corrections. To date, there has been a dearth of PREA studies that include the perceptions of correctional officers ... on the strengths associated with the implementation of PREA include overall climate improvement, increased awareness, and victim ... on the weaknesses associated with the implementation of PREA included staffing crisis, reporting issues, PREA not taken seriously, and PREA not essential. The implications of these themes are ...

Tópico(s): Psychopathy, Forensic Psychiatry, Sexual Offending

2021 - Taylor & Francis | Journal of Crime and Justice

Artigo Revisado por pares

Qingyan Zhao, Yanhong Tang, Emmy Okello, Xi Wang, Congxin Huang,

... EE), se determinó el periodo refractario efectivo auricular (PREA) antes y después de la estimulación en la ... EE rápida en la VPSI. Se determinó el PREA antes de la EV2 y después de la ... EV+EE. En el grupo de EE, el PREA presentó un acortamiento marcado y la dispersión del PREA (dPREA) aumentó de forma significativa (p < 0,05). ... embargo, en el grupo de EV+EE el PREA no se modificó de forma significativa, mientras que ... tras la EV2 más EE. La disminución del PREA puede ser fundamental, pero no es de por ...

Tópico(s): Atrial Fibrillation Management and Outcomes

2009 - Elsevier BV | Revista Española de Cardiología

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Radan Elvis Matias de Oliveira, Gleidson Benevides de Oliveira, Procássia Maria Lacerda Barbosa, Ferdinando Vinícius Fernandes Bezerra, José Fernando Gomes de Albuquerque, Carlos Eduardo Ambrósio, M. A. Miglino, Moacir Franco de Oliveira,

Resumo: O preá é um roedor típico da caatinga pertencente à família Caviidae. Considerando a inexistência de dados sobre o arco aórtico do preá, foi realizado este estudo tendo como objetivo descrever ... dados para biologia da espécie. Foram utilizados vinte preás machos provenientes de estudos anteriores e encontravam-se ... exemplares mais representativos fotografados. O arco aórtico do preá emitiu como ramos colaterais, o tronco braquiocefálico e ... O padrão da formação do arco aórtico do preá assemelhou-se ao observado em outros roedores, tais ...

Tópico(s): Ichthyology and Marine Biology

2015 - Colégio Brasileiro de Patologia Animal (CBPA) | Pesquisa Veterinária Brasileira

Artigo Acesso aberto Revisado por pares

Sylvia Dewilde, M.-L. van Hauwaert, Koen Peeters, Jacques R. Vanfleteren, Luc Moëns,

... unprecedented threonine-rich segment and a 12-residue preA segment which is homologous to the preA segments of other nonvertebrate globin chains. Both domains are linked together by a preA' segment, which is homologous to other preA segments and lacks the threonine-rich segment. Dimerization ... G7.0. A precoding intron occurs at position preA(-27.0) and a bridge intron at occurs preA'(-13.2). We propose a crossover event as ...

Tópico(s): Erythrocyte Function and Pathophysiology

1999 - Oxford University Press | Molecular Biology and Evolution

Artigo Revisado por pares

Hayden P. Smith,

The Prison Rape Elimination Act (PREA) was designed to address sexual violence in prison. While previous has focused on sexual violence occurring in correctional facilities, there has ... or reflections of program following the cimplementation of PREA- within a correctional system. The current study utilizes ... learned" approach to discuss the impact of the PREA Demonstration Project on a state prison system that ... administrators, inmates, and front-line correctional officers regarding PREA is included. Also featured are the "lessons learned" ...

Tópico(s): Psychopathy, Forensic Psychiatry, Sexual Offending

2020 - Elsevier BV | Evaluation and Program Planning

Artigo Revisado por pares

Xianghong Meng, Guozheng Qin, Shiping Tian,

... the present study. Preharvest spray with C. laurentii (PreA) significantly decreased decay index (DI), and postharvest chitosan ... spray when fruits were stored at 0 °C. PreA combination with PCC increased the activities of polyphenol ... phenylalanine ammonia-lyase (PAL) of fruit in storage. PreA + PCC treatment was effective in reducing weight loss ... 38% at 42 d storage as compared to PreA alone at the same stage. In addition, PreA enhanced the ratio of soluble solids content (SSC) ...

Tópico(s): Date Palm Research Studies

2009 - Elsevier BV | LWT

Artigo Revisado por pares

Nina Ajmone Marsan, Francesco Maffessanti, Gloria Tamborini, Paola Gripari, Enrico G. Caiani, Laura Fusini, Manuela Muratori, Marco Zanobini, Francesco Alamanni, Mauro Pepi,

... assess LA volumes (maximum, before atrial active contraction [preA], and minimum). The same evaluation was repeated 6 ... of LA volumes (maximum 43 ± 14 mL/m2, preA 33 ± 12 mL/m2, minimum 23 ± 11 mL/ ... compared to controls (maximum 22 ± 6 mL/m2, preA 13 ± 4 mL/m2, minimum 8 ± 3 mL/ ... volumes significantly decreased (maximum 25 ± 8 mL/m2, preA 18 ± 8 mL/m2, minimum 13 ± 5 mL/ ... year follow-up (maximum 23 ± 7 mL/m2, preA 15 ± 7 mL/m2, minimum 11 ± 5 mL/ ...

Tópico(s): Cardiovascular Function and Risk Factors

2011 - Elsevier BV | American Heart Journal

Artigo Revisado por pares

Nicolas Mansencal, Erik Bouvier, Thierry Joseph, Jean‐Christian Farcot, R Pillière, Alban Redheuil, Pascal Lacombe, Guillaume Jondeau, Olivier Dubourg,

... same hour. Catheterization investigated pre‐A‐wave pressure (preA) and LV ejection fraction (LVEF). Echocardiographic LVEF was ... using WMI (r = 0.91). The correlations between preA and E, E′, and E/E′ were significant ( ... LVEF >50%, no correlation between E/E′ and preA was found (r = 0.18, P = 0.44), ... myocardial infarction, the correlation between E/E′ and preA was significant whatever the localization of myocardial infarction ( ... be the best cut‐off value related to preA > 15 mmHg. We conclude that the mitral inflow‐ ...

Tópico(s): Cardiac Valve Diseases and Treatments

2004 - Wiley | Echocardiography

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Márcio Nogueira Rodrigues, Moacir Franco de Oliveira, José Fernando Gomes de Albuquerque, José Danilo Ayres de Menezes, Antonio Chaves de Assis Neto, Maria Angelica Miglino, Moacir Franco de Oliviera,

Os preás são roedores histricomorfos com atividade reprodutiva e alimentar condicionada a fatores climáticos e pluviométricos. Frente à falta de conhecimento sobre o aparelho reprodutor do preá, este estudo objetivou descrever sua macroscopia e topografia. ... preservar a topografia. Os órgãos genitais masculinos do preá estavam representados pelos testículos, epidídimos, pelas glândulas genitais ... achados descritos para o sistema reprodutor masculino do preá assemelham-se aos descritos para roedores como a ...

Tópico(s): Comparative Animal Anatomy Studies

2013 - UNIVERSIDADE FEDERAL DE SANTA CATARINA | Biotemas

Artigo Revisado por pares

Danielle S. Rudes, Shannon Magnuson, Shannon Portillo, Angela J. Hattery,

The Prison Rape Elimination Act (PREA) reforms correctional institutions via administrative mechanisms and represents a major shift in both correctional policy and workplace practice. Using qualitative data ... U.S. state, finding suggest that staff view PREA as an administrative, safety, and cultural burden, which ... to eliminating prison sexual misconduct/violence, staff see PREA as interfering with their “real” custody/control work. ... implications for the productive implementation and use of PREA and the broader shift to administrative rather than ...

Tópico(s): Sex work and related issues

2020 - SAGE Publishing | Punishment & Society

Artigo Revisado por pares

Aviva Moster, Elizabeth L. Jeglic,

... the implementation of the Prison Rape Elimination Act (PREA), signed into law in 2003. PREA mandates a zero-tolerance policy for sexual assaults ... and it was completed before the implementation of PREA. It found that a majority of the wardens ... study replicates the prior study in a post-PREA environment.

Tópico(s): Gender, Security, and Conflict

2009 - SAGE Publishing | The Prison Journal

Artigo Revisado por pares

Robert A. Schuhmann, Eric J. Wodahl,

... of the Prison Rape Elimination Act of 2003 (PREA), however, reveals that reform through traditional policy making channels is attainable. The passage of PREA has provided reformers with more than optimism. It ... intervention. This manuscript explores the lessons learned from PREA’s success by identifying the traditional barriers to federal legislative prison reform and examining how PREA was able to navigate these obstacles and secure ...

Tópico(s): Crime Patterns and Interventions

2010 - SAGE Publishing | Criminal Justice Policy Review

Artigo Revisado por pares

A. S. McClay, Joseph K. Balciunas,

... This reluctance to undertake pre-release efficacy assessment (PREA) is probably based on concerns that it will ... simulation model to investigate the implications of using PREA as an additional filter in the agent selection ... cost than host-specificity testing, the use of PREA as the first filter can make agent selection ... on host-specificity alone. We discuss examples of PREA and potential approaches. The impact of biocontrol agents ...

Tópico(s): Allelopathy and phytotoxic interactions

2005 - Elsevier BV | Biological Control

Artigo Revisado por pares

Tadashi Abe, Takumi Yamada, Tomoyuki Tomita, Paul A. Easton,

... again during late inspiration as preexpiratory expiratory activity (PREA). We hypothesized that the timing of PEEA and PREA would be changed systematically by posture. Fine-wire ... standing. Abdominal muscle activities during inspiration, PEEA, and PREA, were observed with CO 2 stimulation, both supine ... increase in PEEA and a significant decrease in PREA while subjects were standing; similar changes were seen ...

Tópico(s): Neuroscience of respiration and sleep

1999 - American Physiological Society | Journal of Applied Physiology

Artigo Acesso aberto Revisado por pares

Sherif F. Nagueh, Nasser Lakkis, Katherine J. Middleton, William H. Spencer, William A. Zoghbi, Miguel A. Quiñones,

... along with flow propagation velocity and Ea. LV preA pressure had weak or no relations with mitral, pulmonary venous velocities and atrial volumes. In contrast, preA pressure related strongly to E velocity/flow propagation ... 3.4). In 17 patients with repeat measurements, preA pressure changes were well detected by measuring E ... E/Ea (r=0.8; P<0.001). PreA pressure estimation with these 2 methods was tested ...

Tópico(s): Congenital Heart Disease Studies

1999 - Lippincott Williams & Wilkins | Circulation

Artigo Acesso aberto Revisado por pares

Bintong Yang, Haichao Song, Dingjie An, Dong-Xing Zhang, Sayed Haidar Abbas Raza, Guiqin Wang, Xiaofeng Shan, Qian Ai-dong, Yuan‐Huan Kang, Chunfeng Wang,

... by generating an in-frame deletion of the preA gene, which encodes a periplasmic binding protein, to ... the wild-type strain. The results suggest that preA may negatively regulate the virulence of A. veronii ... will help to further elucidate the function of preA and understand the pathogenesis of A. veronii.

Tópico(s): Vibrio bacteria research studies

2019 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences

Artigo Acesso aberto Revisado por pares

Dongsheng Yang, Qiang Li, Fenghua Zhu, Huachao Cui, Yi Wen, Jirong Qin,

... act (OODA) loop and planning–readiness–execution–assessment (PREA) loop. The aim is to build up a PREA loop-based parallel incident C2 mode and its ... The parallel incident C2 mode based on the PREA loop and OODA loop supports the co-existence ...

Tópico(s): Infrastructure Resilience and Vulnerability Analysis

2022 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Systems Man and Cybernetics Systems

Artigo Revisado por pares

Clare Sears,

... in context of 2003 Prison Rape Elimination Act (PREA). Although PREA addresses a clear and pressing problem (sexual violence ... 2008). Pasko extends this critique by showing that PREA has also effectively criminalized same-sex sexual activity ...

Tópico(s): Psychopathy, Forensic Psychiatry, Sexual Offending

2010 - | Social Justice A Journal of Crime Conflict & World Order

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Moacir Franco de Oliveira, Márcio Nogueira Rodrigues, Êlika Suianne Sousa, José Fernando Gomes de Albuquerque, Carlos Eduardo Bezerra de Moura, Carlos Eduardo Ambrósio, María Angélica Miglino, Moacir Franco de Oliveira,

O preá do semiárido nordestino (Galea spixii Wagler, 1831) é um roedor pertencente à família Caviidae. Pouca literatura é ... todos os nervos do organismo. Foram utilizados 10 preás (cinco machos e cinco fêmeas) que vieram a ...

Tópico(s): Infrared Thermography in Medicine

2010 - UNIVERSIDADE FEDERAL DE SANTA MARIA | Ciência Rural