Yun Kit Yeoh, Yang Sun, Lawrence Yuk Ting Ip, Lan Wang, Francis K.L. Chan, Yinglei Miao, Siew C. Ng,
Abstract Prevotella species in the human gut microbiome are primarily comprised of Prevotella copri , and its diversity and function were recently ... in detail. Much less is known about other Prevotella species in the human gut. Here, we examined the composition of Prevotella species in human guts by mapping publicly available ... dereplicated set of metagenome-assembled genomes (MAGs) representing Prevotella lineages found in human guts. In most human ... the metagenome reads in several cohorts mapped to Prevotella MAGs representing P. stercorea and several other species ...
Tópico(s): Probiotics and Fermented Foods
2022 - Nature Portfolio | Scientific Reports
Junkui Chen, Zhengpeng Li, Xiao‐Fan Wang, Bin Fan, Feilong Deng, Hongwei D. Yu, Xiaolei Ze, Liying Zhu, Yeshi Yin, Yanhong Chen, Jiangchao Zhao, Yunsheng Yang, Xin Wang,
... fermentation, how different carbohydrates affect the Bacteroides and Prevotella enterotypes. Among the 11 substrates (fructo-, galacto-, xylo-, ... starch were found to sustain the growth of Prevotella through batch fermentation. The development of the Prevotella and Bacteroides enterotypes was further simulated in chemostats ... pH were required to sustain the growth of Prevotella copri in the chemostat based on 16S rRNA ... were the carbohydrate-active enzymes associated with the Prevotella enterotype. The Bacteroides enterotype was associated with more ...
Tópico(s): Probiotics and Fermented Foods
2022 - American Society for Microbiology | Microbiology Spectrum
Eija Könönen, Dareen Fteita, Ulvi Kahraman Gürsoy, Mervi Gürsoy,
Oral Prevotella are known as anaerobic commensals on oral mucosae and in dental plaques from early life onwards, including ... P. nigrescens, and P. pallens and non-pigmented Prevotella species. Many Prevotella species contribute to oral inflammatory processes, being frequent ... P. nigrescens), cariotic lesions (P. denticola, Alloprevotella (formerly Prevotella) tannerae), endodontic infections (P. baroniae, P. oris, P. ... P. intermedia, P. nigrescens, and P. pallens). Oral Prevotella species are identified in various non-oral infections ...
Tópico(s): Bacterial Identification and Susceptibility Testing
2022 - Taylor & Francis | Journal of Oral Microbiology
Kasey A. Webb, Olusola Olagoke, Timothy Baird, Jane Neill, Amy Pham, Timothy J. Wells, Kay A. Ramsay, Scott C. Bell, Derek S. Sarovich, Erin P. Price,
... which includes members of the obligately anaerobic genus Prevotella . Despite their commonness, surprisingly little is known about ... genomic diversity and antimicrobial resistance (AMR) potential of Prevotella species and strains in healthy and diseased airways. ... a real-time PCR assay to permit rapid Prevotella species identification and quantification from cultures and clinical ... Assay specificity was validated across a panel of Prevotella and non- Prevotella species, followed by PCR screening of CF and ...
Tópico(s): Cystic Fibrosis Research Advances
2022 - Microbiology Society | Microbial Genomics
Eija Könönen, Ulvi Kahraman Gürsoy,
Prevotella is recognized as one of the core anaerobic genera in the oral microbiome. In addition, members ... of the gastrointestinal and respiratory tracts. Several novel Prevotella species, most of them of oral origin, have ... knowledge is still available of their clinical relevance. Prevotella melaninogenica is among the anaerobic commensals on oral ... months of life onward, and other early colonizing Prevotella species in the oral cavity include Prevotella nigrescens and Prevotella pallens . Oral Prevotella species get ...
Tópico(s): Cystic Fibrosis Research Advances
2022 - Frontiers Media | Frontiers in Microbiology
Kolawole I. Ayeni, David Berry, Lukas Wisgrill, Benedikt Warth, Chibundu N. Ezekiel,
... stool of African NITs include plant-polysaccharide-degrading Prevotella, human-milk oligosaccharide-metabolizing Bifidobacterium, to taxa containing ... 5–12 yearsBacteroides, Bifidobacterium, Clostridium difficile, Desulfovibrio, Lactobacillus, Prevotella, Ruminococcus, SutterellaBacteroidesaHigher abundance in children diagnosed with autism ... Clostridium, Dialister, Faecalibacterium, Haemophilus, Klebsiella Lachnobacterium, Lachnospira Lactobacillus, Prevotella, Phascolarctobacterium, Ruminococcus, SuccinivibrioSutterella, VeillonellaBifidobacteriumbHigher abundance in urban population. ...
Tópico(s): Nutritional Studies and Diet
2022 - Elsevier BV | Trends in Microbiology
Adrian Tett, Edoardo Pasolli, Giulia Masetti, Danilo Ercolini, Nicola Segata,
The genus Prevotella includes more than 50 characterized species that occur in varied natural habitats, although most Prevotella spp. are associated with humans. In the human microbiome, Prevotella spp. are highly abundant in various body sites, ... fundamental in affecting the diversity and prevalence of Prevotella species and strains in the human microbiome. These factors, along with the ecological relationship of Prevotella with other members of the microbiome, likely determine the extent of the contribution of Prevotella to human metabolism and health. Here we review ...
Tópico(s): Clostridium difficile and Clostridium perfringens research
2021 - Nature Portfolio | Nature Reviews Microbiology
Xiaoying Hou, Pei Zhang, Hongzhi Du, Yiqiao Gao, Ruiqi Sun, Si‐Yuan Qin, Yuan Tian, Jing Li, Yuxin Zhang, Weihua Chu, Zunjian Zhang, Fengguo Xu,
... 11, Issue 9 e512 LETTER TO EDITOROpen Access Prevotella contributes to individual response of FOLFOX in colon ... was significantly increased in the S group, whereas Prevotella was higher in NS individuals (Figure 2F–I). ... Jeotgalicoccus, and Sphingomonas) and anaerobic bacteria (i.e., Prevotella) transplantation on FOLFOX efficacy separately. As a result, ... FOLFOX was significantly suppressed with the colonization of Prevotella (p < 0.05), indicated by a reduced tumor ... reflects the proliferation of tumor significantly increased with Prevotella colonization (Figure 3E). In a word, these results ...
Tópico(s): Pancreatic and Hepatic Oncology Research
2021 - Springer Science+Business Media | Clinical and Translational Medicine
Eric J. C. Gálvez, Aida Iljazović, Lena Amend, Till Robin Lesker, Thibaud T. Renault, Sophie Thiemann, Lianxu Hao, Urmi Roy, Achim Gronow, Emmanuelle Charpentier, Till Strowig,
Prevotella spp. are a dominant bacterial genus within the human gut. Multiple Prevotella spp. co-exist in some individuals, particularly those consuming plant-based diets. Additionally, Prevotella spp. exhibit variability in the utilization of diverse complex carbohydrates. To investigate the relationship between Prevotella competition and diet, we isolated Prevotella species from the mouse gut, analyzed their genomes ... competition experiments between species in mice. Diverse dominant Prevotella species compete for similar metabolic niches in vivo, ...
Tópico(s): Clostridium difficile and Clostridium perfringens research
2020 - Cell Press | Cell Host & Microbe
Wing Sun Faith Chung, Alan W. Walker, Douwina Bosscher, Vicenta Garcia‐Campayo, Josef Wagner, Julian Parkhill, Sylvia H. Duncan, Harry J. Flint,
... with a clear stratification of volunteers as either Prevotella -plus ( n = 8; > 0.1% proportional abundance) or Prevotella -minus ( n = 13; ≤0.1% proportional abundance) subjects ... of both faecal Bifidobacterium ( P ≤ 0.01) and Prevotella species ( P ≤ 0.01) in Prevotella -plus volunteers during AXOS supplementation, while Prevotella and Bacteroides relative abundances showed an inverse relationship. ... Anaerostipes hadrus, differed significantly between baseline samples of Prevotella -plus compared to Prevotella -minus individuals. Conclusions The ...
Tópico(s): Gastrointestinal motility and disorders
2020 - BioMed Central | BMC Microbiology
Yuan Huang, Jinhua Tang, Zheng Cai, Keqiang Zhou, Liang Chang, Yinlan Bai, Yueyun Ma,
Th17-mediated mucosal inflammation is related to increased Prevotella bacterial abundance. The actual involvement of Prevotella in the development and accumulation of intestinal Th17 ... remains undefined. Herein, we investigated the role of Prevotella in inducing intestinal Th17 cells in mice. Mice ... water for 4 weeks and then gavaged with Prevotella for 4 weeks. After inoculation, 16S rDNA sequencing was used to verify the colonization of Prevotella in the colon of mice. The IL-17A ... counted by flow cytometry. Systemic immune response to Prevotella colonization was evaluated based on the serum levels ...
Tópico(s): Gastrointestinal motility and disorders
2020 - Hindawi Publishing Corporation | Journal of Immunology Research
Lars Christensen, Stine Vuholm, Henrik M. Roager, Dennis Sandris Nielsen, Łukasz Krych, Mette Kristensen, Arne Astrup, Mads F. Hjorth,
... recent studies have found that subjects with high Prevotella abundances in their gut microbiota lose more weight ... diets rich in fiber than subjects with low Prevotella abundances.We reanalyzed a 6-wk, parallel, randomized ... 30-65 y) healthy, overweight adults by baseline Prevotella-to-Bacteroides ratios and Prevotella abundances. Subjects with no Prevotella were analyzed separately (n = 24). Compared with the ... weights and metabolic and microbiota markers, according to Prevotella groups and diets.The Prevotella abundances correlated inversely ...
Tópico(s): Nutritional Studies and Diet
2019 - Elsevier BV | Journal of Nutrition
... Distinct genetic and functional traits of human intestinal Prevotella copri strains are associated with different habitual diets. ... PDF PubMed Scopus (163) Google Scholar report that Prevotella copri strain-level diversity in the gut microbiome ... Distinct genetic and functional traits of human intestinal Prevotella copri strains are associated with different habitual diets. ... PDF PubMed Scopus (163) Google Scholar report that Prevotella copri strain-level diversity in the gut microbiome ... is Bacteroidetes, of which the genera Bacteroides and Prevotella dominate in human populations. Strains of the genus ...
Tópico(s): Probiotics and Fermented Foods
2019 - Cell Press | Cell Host & Microbe
Gabriela Precup, Dan Cristian Vodnar,
... different communities of bacterial species within the gut. Prevotella species have been correlated with plant-rich diets, ... data on the impact of diet on the Prevotella genus, as a dietary fibre fermenter in the ... of dietary patterns on gut microbial communities, including Prevotella or Prevotella/Bacteroides ratio in particular. Moreover, the role of Prevotella species on health status was also evaluated. Prevotella possess a high genetic diversity, representing one of ... and large intestine of man. The gut commensal Prevotella bacteria contribute to polysaccharide breakdown, being dominant colonisers ...
Tópico(s): Nutritional Studies and Diet
2019 - Cambridge University Press | British Journal Of Nutrition
Akihiro Kaneko, Takayuki Aoki, Fumiaki Ikeda, Ryoichi Kawabe, Tazuko Satoh, Naoki Tsumura,
... used third-generation cephems in dental outpatient clinics. Prevotella, which is the leading cause of odontogenic infections, ... oral closed abscesses, 73% were Streptococcus, 48% were Prevotella, and 47% were Peptostreptococcus. P. intermedia was the most frequently isolated Prevotella sp. and Parvimonas micra (P. micros) was the ... 2)]Table 1Antimicrobial activities against clinical isolates of Prevotella species and Porphyromonas spescies (MIC:μg/mL).Organism ( ... during 2008–2009 showed high MIC values against Prevotella to ABPC (ampicillin), CFDN (cefdinir), and CTRX (ceftriaxone) ...
Tópico(s): Otolaryngology and Infectious Diseases
2018 - Elsevier BV | Journal of Infection and Chemotherapy
Jonna C. Sandberg, Petia Kovatcheva‐Datchary, Inger Björck, Fredrik Bäckhed, Å. Nilsson,
... non-responders) who were characterized by a low Prevotella / Bacteroides ratio. The purpose of the present study was to investigate if the baseline Prevotella / Bacteroides ratio can be used to stratify metabolic ... and 70 years old. The abundance of fecal Prevotella and Bacteroides was quantified with 16S rRNA quantitative ... were grouped in three groups: subjects with highest Prevotella / Bacteroides ratios, “HP”, n = 12; subjects with lowest Prevotella / Bacteroides ratios, “LP”, n = 13; and subjects with ... blood glucose responses to the breakfast independently of Prevotella / Bacteroides ratios ( P < 0.01). However, independently of ...
Tópico(s): Nutritional Studies and Diet
2018 - Springer Science+Business Media | European Journal of Nutrition
Tomaž Accetto, Gorazd Avguštin,
Although the Prevotella are commonly observed in high shares in the mammalian hindgut and rumen studies using NGS approach, the knowledge ... than threefold of hitherto known rumen and hindgut Prevotella species and show that rumen/hindgut Prevotella generally possess extensive repertoires of polysaccharide utilization loci ( ... various plant polysaccharides. These PUL repertoires separate analysed Prevotella into generalists and specialists yet a finer diversity ... found firstly, that they contributed significantly to total Prevotella abundance though much of rumen Prevotella diversity may ...
Tópico(s): Plant and fungal interactions
2018 - Elsevier BV | Systematic and Applied Microbiology
... in humans have linked the increased abundance of Prevotella species at mucosal sites to localized and systemic ... metabolic disorders and low-grade systemic inflammation. Intriguingly, Prevotella abundance is reduced within the lung microbiota of ... with asthma and chronic obstructive pulmonary disease. Increased Prevotella abundance is associated with augmented T helper type ... is in line with the marked capacity of Prevotella in driving Th17 immune responses in vitro. Studies indicate that Prevotella predominantly activate Toll-like receptor 2, leading to ...
Tópico(s): Reproductive tract infections research
2017 - Wiley | Immunology
Produção Nacional
Revisado por pares
Ana Carolina Borsanelli, Elerson Gaetti‐Jardim, Christiane Marie Schweitzer, Lorenzo Viora, Valentina Busin, Marcello P. Riggio, Iveraldo S. Dutra,
... to detect species of the genera Porphyromonas and Prevotella present in the periodontal pocket of sheep with ... Porphyromonas asaccharolytica, Porphyromonas endodontalis, Porphyromonas gingivalis, Porphyromonas gulae, Prevotella buccae, Prevotella intermedia, Prevotella loescheii, Prevotella melaninogenica, Prevotella nigrescens, Prevotella oralis, and Prevotella tannerae. Prevalence and risk analysis were performed using ...
Tópico(s): Endodontics and Root Canal Treatments
2017 - Elsevier BV | Veterinary Microbiology
... technology to analyze fecal microbiota and observed that Prevotella, specifically P copri, was in abundance within gut ... et al provided the first direct evidence that Prevotella-dominant feces from patients with RA and P ... the abundance of P copri with arthritis progression. Prevotella-dominant fecal content increased the Th17 cell population ... and IL-23. Intriguingly, some studies suggested that Prevotella might be regarded as a beneficial bacterium and ... A decrease in bacteria of the Bacteroides–Porphyromonas–Prevotella group was also observed in patients with early ...
Tópico(s): Gut microbiota and health
2016 - Wiley | Arthritis & Rheumatology
Anastassia Gorvitovskaia, Susan Holmes, Susan M. Huse,
... Western European) subjects and the other dominated by Prevotella more often associated with non-Western subjects. The two taxa, Bacteroides and Prevotella, have been presumed to represent consistent underlying microbial ... consistent bacterial taxa associated with either Bacteroides- or Prevotella-dominated communities across the studies. By increasing the ... samples, we found gradients of both Bacteroides and Prevotella and a lack of the distinct clusters in ... is due to the differences in the samples' Prevotella and Bacteroides abundances and does not represent consistent ...
Tópico(s): Diet and metabolism studies
2016 - BioMed Central | Microbiome
Yunfeng Ruan, Lu Shen, Yan Zou, Zhengnan Qi, Jun Yin, Jie Jiang, Liang Guo, Lin He, Zi‐Jiang Chen, Zisheng Tang, Shengying Qin,
Many species of the genus Prevotella are pathogens that cause oral diseases. Prevotella intermedia is known to cause various oral disorders e.g. periodontal disease, periapical periodontitis ... the intra-species genetic differences among strains of Prevotella intermedia of different niches, we isolated a strain Prevotella intermedia ZT from the infected root canal of ... the genomes of other taxa in the genus Prevotella.The raw data set, consisting of approximately 65X- ... 2165 ORFs were predicted. The comparison of the Prevotella intermedia ZT genome sequence with the published genome ...
Tópico(s): Streptococcal Infections and Treatments
2015 - BioMed Central | BMC Genomics
Dareen Fteita, Eija Könönen, Mervi Gürsoy, Eva Söderling, Ulvi Kahraman Gürsoy,
... anaerobes in subgingival biofilms. It is known that Prevotella intermedia sensu lato is able to use estradiol ... in vitro as a virulent factor of the Prevotella intermedia group bacteria, namely P. intermedia, Prevotella nigrescens, Prevotella pallens, and Prevotella aurantiaca. In all experiments, 2 strains of each Prevotella species were used. Bacteria were incubated with the ... Estradiol significantly increased DPPIV activities of the 8 Prevotella strains in a strain- and dose-dependent manner. ...
Tópico(s): Oral microbiology and periodontitis research
2015 - Elsevier BV | Anaerobe
Zhi Li, Han Liu, Guang Li, Kun Bao, Kai Wang, Chao Xu, Yi Yang, Fu Yang, André-Denis G. Wright,
... the CS group were divided into 50 OTUs. Prevotella-like sequences belonging to the phylum Bacteroidetes were ... OL and 77% CS), and sequences related to Prevotella brevis were present in both groups. However, Prevotella shahii-like, Prevotella veroralis-like, Prevotella albensis-like, and Prevotella salivae-like sequences were abundant in the OL ... the CS group, while Succinivibrio dextrinosolvens-like and Prevotella ruminicola-like sequences were prevalent in the CS ... clustered with respect to diets and the genus Prevotella was the dominant bacteria in the rumen of ...
Tópico(s): Gut microbiota and health
2013 - BioMed Central | BMC Microbiology
Lyudmila Boyanova, Rossen Kolarov, Galina Gergova, L Dimitrova, Ivan Mitov,
... and-neck infections often involve anaerobes such as Prevotella species. Aim of the present study was to ... evolution and the factors associated with resistance in Prevotella species to penicillin, clindamycin, metronidazole, tetracycline and β- ... β-lactamase inhibitors (BL/BLIs). In total, 192 Prevotella strains, isolated from patients with oral and head-and-neck infections, were evaluated. Common isolates were Prevotella intermedia and Prevotella melaninogenica within the pigmented species as well as ...
Tópico(s): Antibiotic Use and Resistance
2010 - Elsevier BV | Anaerobe
Aschalew Z. Bekele, Satoshi Koike, Yasuo Kobayashi,
16S rRNA gene-based analysis of rumen Prevotella was carried out to estimate the diversity and diet specificity of bacteria belonging to this genus. Total DNA was extracted from the rumen ... and 1 : 2). Real-time PCR quantification of Prevotella revealed that the relative abundance of this genus ... up to 19.7%, while the representative species Prevotella bryantii and Prevotella ruminicola accounted for only 0.6% and 3.8%, respectively. Denaturing gradient gel electrophoresis analysis for Prevotella revealed shifts in the community composition with the ...
Tópico(s): Plant and fungal interactions
2010 - Oxford University Press | FEMS Microbiology Letters
Luís Alou, María-José Giménez, Francisco Nodar Manso, David Sevillano, M. Torrico, Natalia González, J. J. Granizo, A. Bascones, J. Prieto, J.R. Maestre, L. Aguilar,
... activity of tinidazole against anaerobic periodontal pathogens (25 Prevotella buccae, 18 Prevotella denticola, 10 Prevotella intermedia, 6 Prevotella melaninogenica, 5 Prevotella oralis, 10 Fusobacterium nucleatum and 8 Veillonella spp.) ... spp. and 0.5 μg/mL for other Prevotella spp. Cidal activity was studied by killing curves ... four different strains of the following periodontal isolates: Prevotella spp., Fusobacterium spp. and Veillonella spp. (anaerobes) and ... 1:1:1. When only β-lactamase-negative Prevotella or Fusobacterium strains were tested, significantly higher reductions ...
Tópico(s): Endodontics and Root Canal Treatments
2008 - Elsevier BV | International Journal of Antimicrobial Agents
Kaori Iwahara, Tomoari Kuriyama, Satoshi Shimura, David W. Williams, Maki Yanagisawa, Kiyomasa Nakagawa, Tadahiro Karasawa,
... dentoalveolar infection are highly susceptible to penicillin, some Prevotella strains exhibit resistance to this agent through the ... β-lactamase. The production of β-lactamase by Prevotella spp. is in turn associated with the expression ... determine the prevalence of cfxA and cfxA2 in Prevotella strains by use of real-time PCR and ... β-Lactamase production was seen in 31% of Prevotella isolates, while all isolates of other species were ... was evident for all 48 β-lactamase-positive Prevotella strains. In contrast, neither β-lactamase-negative Prevotella ( ...
Tópico(s): Streptococcal Infections and Treatments
2006 - American Society for Microbiology | Journal of Clinical Microbiology
Mitsuo Sakamoto, Makoto Umeda, Isao Ishikawa, Yoshimi Benno,
... isolates represented the same species of the genus Prevotella . The strains were related to Prevotella dentalis with about 89 % similarity. In addition, the isolates were related to Prevotella sp. oral clone IDR-CEC-0032, which is ... rods. The isolates could be differentiated from other Prevotella species by d -mannitol, d -melezitose, d -sorbitol ... EPPA7 was significantly different from that of other Prevotella species. Compared with other Prevotella species, only these six strains contained dimethyl acetals. ...
Tópico(s): Infective Endocarditis Diagnosis and Management
2005 - Microbiology Society | INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
Hrisi Bahar Tokman, Müzeyyen Mamal Torun, Mehmet Demırci, Bekir Kocazeybek,
... lactamase production and the antimicrobial resistance of 72 Prevotella species and 48 Porphyromonas species isolated from different ... and imipenem were tested for each strain.Nineteen Prevotella melaninogenica, 18 Prevotella intermedia, 16 Prevotella denticola, 11 Prevotella loescheii and 8 Prevotella bivia strains were identified. Four were clindamycin resistant. ... anaerobes, the current local susceptibility profile of our Prevotella and Porphyromonas species will establish the basis for ...
Tópico(s): Infective Endocarditis Diagnosis and Management
2005 - Karger Publishers | Chemotherapy