Jeremy Rundall, Terry Delaney, Jeremy Bugler, Charles Raw, Richard Buckle, James Margach, (Miss) Hilary Martin, D S-T, Elizabeth Nicholas, Nicholas Carroll Diplomatic Correspondent, Jo Hollander, Harold Hobson, Peter Gillman, Nicholas Herbert, John Rex, Julian Jebb, John Lambert, Francis Wyndham, Michael P L Caton Chairman, Edmund Cooper, Kenneth Pearson, Antony Terry, Roger Nuttall, P D, Julian Symons, C Mf Deakin Director, Cal McCrystal, Dorothy Guedes, Elizabeth Good, Margaret Cosia, Montague Haltrecht, Henry Brandon, Alix Coleman, John Russell, Hugh Brogan, Linda Blandford, Max Marquis, Timothy Giles, Philip Clarke, Patrick Campbell, Vivian Jenkins, Michel Gabrysiak, Murray Sayle, Edmund Stevens, Sir Ian Lyle, John Ballantine, Tom Margerison, Laurence Marks, William Manchester, Robin Marlar, Thomas Sterling, Robert Troop, Jack Nicoll, Stella Frank, Cyril Connolly, Herbert Thompson, Colin Chapman Education Correspondent, Raymond Mortimer, Robert Skidelsky, Ken Martin, Ivan Sharpe, Maxwell Boyd, Lawrence D Hills Director-Secretary, Judith Jackson, Evelyn Irons, Nicholas Carroll, Paul Martin, Antony Stephens, Geoffrey Sumner, Luis Bernado Honwana, John Barry, D H Dale, Jeffrey Bernard, Bernard Eaton, Roger Mortimer, David Griffiths, Malcolm Winton, Ernestine Carter, Desmond Shawe-Taylor, Gina Jones (final year, LSE), Meriel McCooey, Gwen Nuttall, Nicholas Wollaston, Stephen Aris, Lanning Roper, E Schleyer-Saunders, Dilys Powell, Brigid Keenan, J L Blonstein, Peter Wilsher Editor, M. H., David Wiggins, Felix Aprahamian, Arnold Field, Ewan Mitchell, Henry Longhurst, Owen Chadwick, Dr Alfred Byrne Medical Correspondent, James Margach Political Correspondent, Geoffrey Broadbent, Christopher Ricks, Hunter Davies, Arthur Hopcraft, (Mrs) J Hoare, Michael Moynihan, Brian Glanville, Keith Richardson, T Verschoyle, Peter Dunn, Colin Chapman, Michael Green, C. H. O'd. Alexander, Ian Coulter Industrial Editor, Maurice Wiggin, Bob Millard, Doris Langley Moore, George Knupffer, Margery Fisher, Sylvia Millar, Harlow Unger, Kenneth Konstam, John Mattison, William M. Clarke,
Oil inch deep as Operation Canute starts More troops for the beaches Air firm tried to keep £2m of profits from Ministry An Insight inquiry Holiday road ...
1967 - Gale Group | Sunday Times HA GDA
Produção Nacional
Giselly Encinas, Veronica Y. Sabelnykova, Eduardo Carneiro de Lyra, Maria Lúcia Hirata Katayama, Simone Maistro, Pedro Wilson Mompean de Vasconcellos Valle, Gláucia Fernanda de Lima Pereira, Lívia Munhoz Rodrigues, Pedro Adolpho de Menezes Pacheco Serio, Ana Carolina Ribeiro Chaves de Gouvêa, Felipe C. Geyer, Ricardo Alves Basso, Fátima Solange Pasini, Maria del Pilar Esteves Diz, Maria Mitzi Brentani, João Carlos Guedes Sampaio Góes, Roger Chammas, Paul C. Boutros, Maria Aparecida Azevedo Koike Folgueira,
... Diz 1 , Maria Mitzi Brentani 1 , João Carlos Guedes Sampaio Góes 3 , Roger Chammas 1 , Paul C. Boutros 2, 4, 5 ...
Tópico(s): DNA Repair Mechanisms
2018 - Impact Journals LLC | Oncotarget
Kenneth Blaxter, Philip Jacobson, Uppsala, Alec McGivan, Campaign Manager, Victoria McKee, Frances Gibb, Legal Affairs Correspondent, Holly Hill, Webb, Vijitha Yapa, Samuel Van Culin, Geraldine Norman, Sale Room Correspondent, Gordon Allan, Cliff Feltham, Gerald Hubbard, The Times Private Handicapper, Dennis Dwyer, Sally Brompton, John Best Ottawa, Michael Binyon, Noel Goodwin, Carol Leonard, Harry Eyres, Margaret Hough, Rosemount, Deganwy, Richard Streeton, Eduardo Cué Asunciôn, Michael McCarthy, Colin Narbrough, John Spicer, Employment Affairs Correspondent, Joe Joseph, Roger Lean-Vercoe, Mitchell Platts, Golf Correspondent, Michael Tate, Ruth Gledhill, Patrick Howarth, Rodney Cowton, Jill Sherman, Social Services Correspondent, C. H. Gimingham President, Rodney Cowton, Transport Correspondent, Lawrence Lever, Thomson Prentice Science Correspondent, Peter Waymark, Ray Kennedy, Henry Stanhope, Martin Fletcher, Political Reporter, Marcus Williams, Andrew McEwen and Philip Webster, Diana Geddes, Jeremy Taylor, Barry Fantoni, John Percival, Richard Thomson, Banking Correspondent, John Hennessy, Russell Vallance, John Kilbracken, Dennis Signy, Philip Webster, Chief Political Correspondent, Geoffrey Wheeler, (Michael Phillips), Timothy Finn, Patricia Davies, Plainfield, Judge outlines key questions for jury, William Holmes, John Grigg, Barbara Amiel, Alexander C. McKee, Craig Brown, Peter Bryan, Alexandra Jackson, Roland Rudd, Sheila Gunn, Political Staff, Richard Evans Political Correspondent, W. G. Chaloner, President, John Clare Education Correspondent, Martin Searby, Barry Pickthall, Ian Ross, Sarah Thompson Education Reporter, David Tremayne, Geoffrey Foster, Teresa Gorman, Derek Harris, Industrial Editor, Pat Butcher, Athletics Correspondent, John Goodbody, Ian Smith, Doug McAVOY, John Bowes, John Wilcockson, Anthony Parsons, Alan Franks, Robert Grieves, Michael Seely, Alan Lee, Peter Dear and Peter Davalle, E. W. Swanton, David Sinclair, Alan McGregor, John Woodcock, Cricket Correspondent, Frances Gibb Legal Affairs Correspondent, Derek Harris, John Young Agriculture Correspondent, Nicholas Wood, Political Reporter, Robert Fisk, Pat Butcher Athletics Correspondent, Richard Morrison, David Powell, Jack Bailey, Lee Rodwell, Andrew Davidson, Pearce Wright, Science Editor, Colin Campbell, David Young Energy Correspondent, David Hands, Rugby Correspondent, Michael Coleman, Craig Seton and Robin Young, Mary Dejevsky, Richard Williams, Ray Heath,
... Prince Paul Sapieha Dr Nathaniel Miller Senhor Fernando Guedes Dr John H. Northrop Births, Marriages, Deaths Calls ...
1987 - Gale Group | TDA
Alexis Grand’Homme, Émilie Janots, Valérie Bosse, Anne‐Magali Seydoux‐Guillaume, Roger De Ascenção Guedes,
Tópico(s): Geology and Paleoclimatology Research
2016 - Springer Science+Business Media | Mineralogy and Petrology
S. King, George Cole, Andreas Loizou, Anthony Harris, Gowrie, Chairman, Jon Ashworth, Andrew Pierce, Political Correspondent, Beloff, Nick Nuttall, Chris Ward, Adrian Lee, Grace Bradberry, Arthur Snell, Simon Barnes, John Morgan, Mark Souster, Richard Hobson, Philip Howard, Carol Midgley, Stephen Prower (Research Officer), Nicholas Lloyd, Jeremy Kingston, Joanna Bale, I. A. Shapiro, Richard Ford Home Correspondent and Robert Crampton, Richard Foster, Carl Mortished, Morag Preston, Gillian Maxey, R. W. Johnson and Tom Rhodes, Alice Thomson and Alan Hamilton, Geoff Brown, Robert Sheehan, Bridge Correspondent, Robert Miller, John O'Leary Education Editor, Jonathan Prynn, Transport Correspondent, Bridget Harrison, Charles Bremner and Andrew Pierce, Janet Bush, Economics Editor, Peter Capella, Ruth Gledhill, Debra Craine, Julian Critchley, Raymond Keene Chess Correspondent, Bobby Robson, Rachel Kelly, Martin Barrow, Dalya Alberge Arts Correspondent, Nicholas Watt, Michael Clark, Patrick Deuchar (Chief Executive), David H. Walton, Quentin Letts, John Kavanagh, Tony Waterson, Peter Barnard, Nigella Lawson, J. R. Lowerson, Ian S. MacPhail (Chairman), Robert Miller Banking Correspondent, Philip Bassett, Brenda Maddox, Richard Buttrey, Nicholas Harling, Lin Jenkins, Barry Millington, Christopher Jamison Head Master, Gillian Bowditch, Scotland Correspondent, Danielle Vyse, Michael Prestage, Marcus Binney, Raymond Keene, Matthew Clarkc, Emma Wilkins, Leyla Linton, Frances Gibb, Legal Correspondent, Chris Partridge, Bronwen Maddox, PHS, Eric Reguly, Richard Owen, David Powell, Athletics Correspondent, Oliver Holt, Damian Whitworth, Roger Boyes, Tracey Knight, Sarah Cunningham, Oliver August, Philip Webster, Political Editor, G. Silverstone, Giles Whittell, Jason Nisse, Christopher Walker, Robert Crampton, Chris Parker, Jane Shilling, Rob Hughes, Football Correspondent, Jason Nissé, Jerry Brahm, Kathryn Knight, Srikumar Sen Boxing Correspondent, Matthew Parris, Richard Evans Racing Correspondent, Anjana Ahuja, Christine Webb, Michael Hornsby, Walter Gammie, Anthony Loyd, Peter Riddell, Ben MacIntyre, Ray Hatley, Richard Beeston, Brian Glanville, Philip Webster, Simon Jenkins, Darryl Mead (Senior Curator), Tim Jones, Fraser Nelson, Mark Henderson, Alan Coren, Peter Gardner, Daniel Rosenthal, Benedict Nightingale, Nigel Powell, Tom Rhodes, Dr Thomas Stuttaford, Marianne Curphey, Lindsay Nicolle, James Christopher, Michael Henderson, David Maddock, Alice Thomson, Political Reporter, Shane Meadows, Alasdair Murray, Matthew Bond, Dr Keyboard, Christopher Irvine, Christine Buckley, Industrial Correspondent,
... cuts short joy of Swiss Sport in Brief Guedes wins Greening stays Drugs ban Salford signings Towers ...
1997 - Gale Group | TDA
Dominique Gasquet, Jean‐Michel Bertrand, Jean‐Louis Paquette, Jérémie Lehmann, Gueorgui Ratzov, Roger De Ascenção Guedes, Massimo Tiepolo, Anne‐Marie Boullier, Stéphane Scaillet, Sébastien Nomade,
Abstract U-Pb and Th-Pb dating of monazite from hydrothermal quartz veins (“Alpine veins”) from the Lauzière massif (North Belledonne) together with Ar/Ar ages of adularias from the same veins constrain the age of the last tectono-metamorphic events that affected the External Crystalline Massifs (ECM). Ages obtained are surprisingly young. The study of the structural context of the veins combined with our chronological data, allow us to propose a tectonic scenario of the northern ECM for the 15-5 Ma ...
Tópico(s): Geology and Paleoclimatology Research
2010 - EDP Sciences | BSGF – Earth Sciences Bulletin
By DAVID WOOD, From MICHAEL KNIPE, By BRIAN MacARTHUR, Education Correspondent, By a Staff Reporter, BY OUR POLITICAL EDITOR, From LOUIS HEREN, FROM OUR CORRESPONDENT, By Our Air Correspondent, Our Home Affairs Correspondent, By CLIVE BORRELL, By Our Political Staff, BY A STAFF REPORTER, By HUGH DE WET, Our Colchester Correspondent, FROM OUR TRAVEL CORRESPONDENT, By PETER EVANS, Race Relations Corresponden, BY OUR LABOUR STAFF, By BYRON ROGERS, From PETER STRAFFORD, FROM OUR OWN CORRESPONDENT, From ROGER BERTHOUD, From Gretel Spitzer, From Our Own Correspondent, From EDWARD MORTIMER, From IAN McDONALD, From PAUL MARTIN, From Our Correspondent, From PETER HAZELHURST, From DAVID BONAVIA, From DAN VAN DER VAT, By Henry Raynor, By Leonard Buckley, By William Gaunt, By William Mann, Music Critic, C. G., By Geraldine Keen, Sale Room Correspondent, By GEORGE CLARK Political Staff, By PAUL ROUTLEDGE, FRANK ROBERTS, PHS, LOUIS HEREN, JOHN BIGGS-DAVISON., JUNE CLARK., R. KNOWLES, BENEDICT BIRNBERG., WINSTON P. MOSES., S. H. SHARPLEY, R. ST. BARBE BAKER, ANNE C. VALENTINE., By Robin Day, SYLVIA BARBANELL., FORTESCUE., G. WARDEN., G. I. A. D. Draper, DOUGLAS WIMBERLEY., By PHILIP HOWARD, By Our Bridge Correspondent, By Nature-Times News Service, Prof. G. Wilson Knight, From MICHAEL PHILLIPS, Racing Correspondent, By Our Northern Racing Correspondent, By Our Racing Staff, By Our Newmarket Correspondent, By RONALD FAUX, From GORDON ALLAN, By GEOFFREY GREEN, Football Correspondent, By Our Lacrosse Correspondent, By REX BELLAMY, Tennis Correspondent, By NEIL ALLEN, Boxing Correspondent, By STUART MARSHALL, By HUGH STEPHENSON Economics Correspondent, By DAVID JONES, Political Staff, By WARWICK BROPHY, By MAURICE CORINA, By DAVID MILLHAM, By ANTHONY ROWLEY, By DENNIS DWYER, By GILES SMITH, By PETER HILL, By CLIFFORD WEBB, Midland Industrial Correspondent, KENNETH OWEN, DAVID MILLHAM, By JOHN ARMYTAGE, By DAVID DAVIS, BY THE FINANCIAL EDITOR, By Our Economics Correspondent, By ARTHUR REED, Air Correspondent, BY ERIC WIGHAM, DE L'ISLE, PETER JAY, David Jones, Patricia Tisdall, Andrew Graham, Pamela Buonaventura, Elizabeth Ray, P.V.P, P.V.P., P. J., A.G., David Davis,
... their differences but rifts remain, Panayotis Psaras, Fernando Guedes, Politics and sport cannot be split, Howell says, ...
1969 - Gale Group | TDA
Produção Nacional
Revisado por pares
Roger Antoniaci Guedes, Aline Cristiane Planello, Denise Carleto Andia, Naila Francis Paulo de Oliveira, Ana Paula de Souza,
It is evident that the accumulation of periodontal pathogens over the teeth surface triggers periodontitis; however, its aggravation and severity depend on other elements such as environmental factors, systemic health and the host genetic and/or epigenetic background. To address this issue, we investigated the association of two genetic polymorphisms placed on promoter region of SOCS1 gene with chronic periodontal disease. SOCS1 regulates Jak/Kinase signaling pathway and changes in its mRNA expression ...
Tópico(s): Inflammatory mediators and NSAID effects
2015 - Elsevier BV | Meta Gene
Émilie Janots, Alexis Grand’Homme, Matthias Bernet, Damien Guillaume, Edwin Gnos, Marie‐Christine Boiron, Magali Rossi, Anne‐Magali Seydoux‐Guillaume, Roger De Ascenção Guedes,
Abstract. A multi-method investigation into Lauzière granite, located in the external Belledonne massif of the French Alps, reveals unusually hot hydrothermal conditions in vertical open fractures (Alpine-type clefts). The host-rock granite shows sub-vertical mylonitic microstructures and partial retrogression at temperatures of < 400 ∘C during Alpine tectonometamorphism. Novel zircon fission-track (ZFT) data in the granite give ages at 16.3 ± 1.9 and 14.3 ± 1.6 Ma, confirming that Alpine metamorphism was ...
Tópico(s): High-pressure geophysics and materials
2019 - Copernicus Publications | Solid Earth
Produção Nacional
Revisado por pares
Rodrigo Guedes de Camargo, Gabrielli Guerra, Roger Leonardo Rosa, Michel Calmet, Mônica Yuri Takito, Émerson Franchini,
Tópico(s): Sports injuries and prevention
2019 - Springer Science+Business Media | Sport Sciences for Health
Patrícia Guedes Garcia, Burkhard Malorny, M. Rosario Rodicio, Roger Stephan, Herbert Hächler, Beatriz Guerra, C. Lucarelli,
Salmonella enterica serovar 4,[5],12:i:- is a monophasic variant of S. Typhimurium incapable of expressing the second-phase flagellar antigen (fljAB operon), and it is recognized to be one of the most prevalent serovars causing human infections. A clonal lineage characterized by phage type DT193, PulseNet PFGE profile STYMXB.0131 and multidrug resistance to ampicillin, streptomycin, sulphonamides and tetracycline (R-type ASSuT) is commonly circulating in Europe. In this study we determined the deletions ...
Tópico(s): Bacteriophages and microbial interactions
2016 - Frontiers Media | Frontiers in Microbiology
Claire F. Verschraegen, Tul Sittisomwong, Andrzej P. Kudelka, Ernesto de Paula Guedes, M Steger, Tarra Nelson-Taylor, Monique Vincent, Roger Rogers, E. Neely Atkinson, John J. Kavanagh,
PURPOSE: To determine the efficacy and toxicity of docetaxel in patients with müllerian carcinoma resistant to paclitaxel. PATIENTS AND METHODS: Thirty-two patients with epithelial ovarian cancer, fallopian tube cancer, or primary peritoneal cancer who failed paclitaxel-based chemotherapy received either 100 or 75 mg/m 2 of docetaxel every 3 weeks. Resistance to paclitaxel was defined as either progression of disease during treatment, failure to achieve regression of disease after at least four ...
Tópico(s): Endometrial and Cervical Cancer Treatments
2000 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
Produção Nacional
Revisado por pares
Arlindo A. Moura, Erdoğan Memili, Antônia Portela, Arabela Guedes de Azevedo Viana, Ana Luiza Cazaux Velho, Maria Júlia Barbosa Bezerra, Fábio Róger Vasconselos,
Molecular components of sperm and in the media surrounding them influence male fertility. In this regard, seminal plasma proteins and metabolites modulate various reproductive events, including sperm motility and capacitation, cell protection, acrosome reaction, fertilization and embryonic development. Empirical associations between seminal proteins and metabolites and fertility indicate that these molecules are potential molecular markers of male reproductive status in cattle and other species.
Tópico(s): Erythrocyte Function and Pathophysiology
2018 - Colégio Brasileiro de Patologia Animal (CBPA) | Animal Reproduction
Valeria Calsolaro, Paul M. Matthews, Cornelius K. Donat, Nicholas R Livingston, Grazia Daniela Femminella, Sandra Silva Guedes, Jim Myers, Zhen Fan, Robin J. Tyacke, Ashwin Venkataraman, Robert Perneczky, Roger N. Gunn, Eugenii A. Rabiner, Steve Gentleman, Christine A. Parker, Philip S. Murphy, Paul Wren, Rainer Hinz, Magdalena Sastre, David Nutt, Paul Edison,
11C-BU99008 is a novel positron emission tomography (PET) tracer that enables selective imaging of astrocyte reactivity in vivo. To explore astrocyte reactivity associated with Alzheimer's disease, 11 older, cognitively impaired (CI) subjects and 9 age-matched healthy controls (HC) underwent 3T magnetic resonance imaging (MRI), 18F-florbetaben and 11C-BU99008 PET. The 8 amyloid (Aβ)-positive CI subjects had higher 11C-BU99008 uptake relative to HC across the whole brain, but particularly in frontal, ...
Tópico(s): S100 Proteins and Annexins
2021 - Springer Nature | Molecular Psychiatry
Produção Nacional
Walter Leal Filho, Diogo Guedes Vidal, Chen Chen, Maria A. Petrova, Maria Alzira Pimenta Dinis, Peter Yang, Steven Rogers, Lorena del Carmen Álvarez-Castañón, Ilija Đjekić, Ayyoob Sharifi, Samara da Silva Neiva,
The implementation of the Sustainable Development Goals (SDGs) requires much planning and the provision of resources, especially regarding the necessary investments, technologies and infrastructures needed. Yet, it is presently unclear how available these elements are, what gaps exist, what changes have taken place in terms of their availability since the adoption of the SDGs and what their requirements will be in the future. The knowledge gap has become even more concerning because of the impact ...
Tópico(s): Energy and Environment Impacts
2022 - Springer Science+Business Media | Environmental Sciences Europe
Produção Nacional
Revisado por pares
Deisy Johana Diaz Sanchez, Fábio Roger Vasconcelos, Antônio C. A. Teles‐Filho, Arabela Guedes de Azevedo Viana, Aline Maria Araújo Martins, Marcelo Valle de Sousa, Mariana S. Castro, Carlos André Ornelas Ricart, Wagner Fontes, M. Bertolini, Ivan Cunha Bustamante‐Filho, Arlindo A. Moura,
Abstract The present study was conducted to decipher the proteome of in vivo‐produced pre‐implantation ovine embryos. Ten locally adapted Morana Nova ewes received hormonal treatment and were inseminated 12 hr after ovulation. Six days later, 54 embryos (morula and blastocyst developmental state) were recovered from eight ewes and pooled to obtain sufficient protein for proteomic analysis. Extracted embryo proteins were analysed by LC‐MS/MS, followed by identification based on four database searches ( ...
Tópico(s): MicroRNA in disease regulation
2021 - Wiley | Reproduction in Domestic Animals
Produção Nacional
Revisado por pares
Gabriel Camargo-Silva, Larissa Córdova Turones, Kellen Rosa da Cruz, Karina Pereira Gomes, Michelle Mendanha Mendonça, Allancer Nunes, Itamar Couto Guedes de Jesus, Diego Basile Colugnati, Aline Priscila Pansani, Roger L.H. Pobbe, Robson A.S. Santos, Marco Antônio Peliky Fontes, Sílvia Guatimosim, Carlos H. Castro, Danielle Ianzer, Reginaldo Nassar Ferreira, Carlos Henrique Xavier,
Prior evidence indicates that ghrelin is involved in the integration of cardiovascular functions and behavioral responses. Ghrelin actions are mediated by the growth hormone secretagogue receptor subtype 1a (GHS-R1a), which is expressed in peripheral tissues and central areas involved in the control of cardiovascular responses to stress.In the present study, we assessed the role of ghrelin - GHS-R1a axis in the cardiovascular reactivity to acute emotional stress in rats.Ghrelin potentiated the tachycardia ...
Tópico(s): Adipose Tissue and Metabolism
2018 - Elsevier BV | Life Sciences
Carlos Alberto Ávila Araújo, Aline Michelle Sima, Roger Miranda Guedes, Karine Souza Resende,
Este texto apresenta os resultados de uma pesquisa realizada com os professores da Escola de Ciência da Informação da UFMG sobre os seguintes assuntos: a ciência da informação como uma ciência social; a ciência da informação como uma ciência interdisciplinar; a ciência da informação como uma ciência pós-moderna; a natureza da relação entre a ciência da informação e a biblioteconomia. A cada entrevistado solicitou-se, ainda, que indicasse dez autores e dez obras da área de ciência da informação que ...
Tópico(s): Science and Science Education
2007 - Universidade Federal de Minas Gerais, Escola de Ciência da Informação | Perspectivas em Ciência da Informação
Produção Nacional
Revisado por pares
José Roberto Pereira Guedes, Solange Carrasco, Cláudia Maris Ferreira, Leoni Villano Bonamin, Willian Marques de Souza, Cláudia Goldenstein‐Schainberg, Edwin Roger Parra, Vera Luíza Capelozzi,
Ultra High Dilutions (UHD) are diluted beyond the Avogadro limit with dynamization (dilution with succussion). The process of anuran amphibian metamorphosis is controlled by thyroid hormones, including the resorption of the tadpole tail.A randomized and blinded study was performed to investigate the influence of triiodothyronine (T3) 5·10(-24)M (10cH) on apoptosis induced by T3 100 nM in Rana catesbeiana tadpoles' tail tips, in vitro. Explants were randomized to three groups: control: no T3 in pharmacological ...
Tópico(s): Environmental Toxicology and Ecotoxicology
2011 - Thieme Medical Publishers (Germany) | Homeopathy
Produção Nacional
Revisado por pares
Luciana Nogueira de Sousa Andrade, Andréia Hanada Otake, Sílvia Guedes Braga Cardim, Felipe Ilelis da Silva, Mariana Mari Ikoma Sakamoto, Tatiane Katsue Furuya, Miyuki Uno, Fátima Solange Pasini, Roger Chammas,
Abstract Extracellular vesicles (EVs) are emerging as key players in intercellular communication. EVs can transfer biological macromolecules to recipient cells, modulating various physiological and pathological processes. It has been shown that tumor cells secrete large amounts of EVs that can be taken up by malignant and stromal cells, dictating tumor progression. In this study, we investigated whether EVs secreted by melanoma cells in response to chemotherapy modulate tumor response to alkylating ...
Tópico(s): Circular RNAs in diseases
2019 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Michael Nadson Santos Santana, Diego Santos Souza, Rodrigo Miguel‐dos‐Santos, Thallita Kelly Rabelo, Carla Maria Lins de Vasconcelos, Juliana M. Navia‐Pelaez, Itamar Couto Guedes de Jesus, Júlio Alves da Silva-Neto, Sandra Lauton‐Santos, Luciano dos Santos Aggum Capettini, Sílvia Guatimosim, Russell G. Rogers, Márcio Roberto Viana dos Santos, Valter Joviniano Santana‐Filho, Thássio Mesquita,
Background Currently viewed as a complementary non-pharmacological intervention for preventing cardiac disorders, long-term aerobic training produces cardioprotection through remote ischemic preconditioning (RIPC) mechanisms. However, RIPC triggered by acute exercise remains poorly understood. Although resistance exercise (RE) has been highly recommended by several public health guidelines, there is no evidence showing that RE mediates RIPC. Hence, we investigated whether RE induces cardiac RIPC through ...
Tópico(s): Cardiac Imaging and Diagnostics
2018 - Elsevier BV | Journal of Molecular and Cellular Cardiology
Produção Nacional
Revisado por pares
Ernesto de Meis, V.R. Pinheiro, Mauro Musa Zamboni, Maria Teresa Santos Guedes, Ilda A.M. Castilho, Maria Mercedes K. Martinez, Marys Stella O. Leda, Neura P. R. Silveira, Vivian M. Rumjanek, Roger A. Levy,
Thrombosis is highly prevalent in cancer patients, being accepted as a bad prognosis marker. The importance of various mechanisms involved in the thrombophilic state of lung cancer patients is not well understood. In this prospective study, involving 109 unselected patients with lung adenocarcinoma, thrombosis was present in 24% of patients and affected survival in a bivariable model. However, in a multivariable evaluation, considering all the factors under study, only LAC and IgM anti-β2 GP I modified ...
Tópico(s): Inflammatory Biomarkers in Disease Prognosis
2009 - Taylor & Francis | Cancer Investigation
Produção Nacional
Revisado por pares
Ernesto de Meis, V.R. Pinheiro, Maria Aparecida Limongi Loures, MARIA MERCEDES KOTOUC, Mauro Zamboni, MARIA TEREZA S. GUEDES, Ailce S. Barros, Ilda A.M. Castilho, Roger A. Levy,
Abstract: There is a high incidence of thrombosis in cancer patients. Retrospective studies indicate that lupus anticoagulant (LA) antibodies can be a thrombosis risk factor in cancer. In 77 patients with different forms of cancer LA and thrombosis incidence were retrospectively evaluated. In a prospective study, with 42 lung adenocarcinoma patients, we measured plasma LA, fibrinogen, factor VIII (FVIII), and thrombosis incidence. A high frequency of LA and thrombosis were observed in both studies. ...
Tópico(s): Cardiovascular Disease and Adiposity
2007 - Wiley | Annals of the New York Academy of Sciences
Amy Robertson, Fabian Wendt, Jason Jonkman, Wojciech Popko, Habib J. Dagher, Sébastien Gueydon, Jacob Qvist, Felipe Vittori, José Azcona, Emre Uzunoglu, C. Guedes Soares, Rob Harries, Anders Yde, Christos Galinos, Koen Hermans, Jacobus De Vaal, Pauline Bozonnet, Ludovic Bouy, Ilmas Bayati, Roger Bergua, Josean Galván, I. Mendikoa, Carlos Barrera Sánchez, Hyunkyoung Shin, Sho Oh, Climent Molins, Yannick Debruyne,
This paper summarizes the findings from Phase II of the Offshore Code Comparison, Collaboration, Continued, with Correlation project. The project is run under the International Energy Agency Wind Research Task 30, and is focused on validating the tools used for modeling offshore wind systems through the comparison of simulated responses of select system designs to physical test data. Validation activities such as these lead to improvement of offshore wind modeling tools, which will enable the development ...
Tópico(s): Fluid Dynamics and Vibration Analysis
2017 - Elsevier BV | Energy Procedia
Produção Nacional
Revisado por pares
K. Barbara Sahlin, Indira Plá, Jéssica de Siqueira Guedes, Krzysztof Pawłowski, Roger Appelqvist, György Marko‐Varga, Gilberto B. Domont, Fábio César Sousa Nogueira, Aleksander Giwercman, Aniel Sánchez, Johan Malm,
Long term effect of testosterone (T) deficiency impairs metabolism and is associated with muscle degradation and metabolic disease. The association seems to have a bidirectional nature and is not well understood. The present study aims to investigate the early and unidirectional metabolic effect of induced T changes by measuring fasting amino acid (AA) levels in a human model, in which short-term T alterations were induced. We designed a human model of 30 healthy young males with pharmacologically ...
Tópico(s): Pharmacological Effects and Assays
2021 - Multidisciplinary Digital Publishing Institute | Life
Produção Nacional
Roger de Miranda Guedes, María Aparecida Moura, Eduardo José Wense Dias,
Introdução: A linguagem é o ponto de partida para o estabelecimento da interação verbal entre interlocutores, não apenas em uma situação formalizada pela escrita ou pelo cenário midiático, mas em todos os momentos em que se quer estabelecer uma ação comunicativa entre interlocutores a linguagem é a ponte que une pessoas e que permite a geração de conhecimento. Objetivo: Apresenta reflexões teóricas acerca da indexação social, entendida como processo de representação da informação em espaços sociais ...
Tópico(s): Education and Digital Technologies
2012 - UNIVERSIDADE ESTADUAL DE LONDRINA | Informação & Informação
Produção Nacional
Roger Alexandre Nogueira Gontijo, Janice Guedes de Carvalho, Rubens José Guimarães, Antônio Nazareno Guimarães Mendes, Wander Eustáquio de Bastos Andrade,
The objective of this work was to quantify the leaf micronutrient levels in coffee seedlings, to establish critical ranges in the experiment carried out in Federal University of Lavras, from May/2002 to January/2003. A random block design was arranged in a 6 x 4 factorial scheme (six fertilization levels and four sampling times), with four replications (nine plants were evaluated per plot). The evaluations were performed when the seedlings reached the stages of 3, 4, 5 and 6 pairs of leaves. The fertilization ...
Tópico(s): Agricultural and Food Sciences
2007 - UNIVERSIDADE FEDERAL DE LAVRAS | Coffee Science
Produção Nacional
Revisado por pares
Ricardo Bassil Lasmar, Bernardo Portugal Lasmar, Roger Keller Celeste, Daniela Baltar da Rosa, Daniella de Batista Depes, Reginaldo Guedes Coelho Lopes,
Tópico(s): Gynecological conditions and treatments
2012 - Elsevier BV | Journal of Minimally Invasive Gynecology
Produção Nacional
Revisado por pares
Jéssica de Siqueira Guedes, Indira Plá, K. Barbara Sahlin, Gustavo Monnerat, Roger Appelqvist, György Marko‐Varga, Aleksander Giwercman, Gilberto B. Domont, Aniel Sánchez, Fábio César Sousa Nogueira, Johan Malm,
Testosterone is a hormone that plays a key role in carbohydrate, fat, and protein metabolism. Testosterone deficiency is associated with multiple comorbidities, e.g., metabolic syndrome and type 2 diabetes. Despite its importance in many metabolic pathways, the mechanisms by which it controls metabolism are not fully understood. The present study investigated the short-term metabolic changes of pharmacologically induced castration and, subsequently, testosterone supplementation in healthy young ...
Tópico(s): Muscle metabolism and nutrition
2022 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Ivy Jungerman, Julia Toyota, Neyller Patriota Montoni, Elma Heitmann Mares Azevedo, Renata Lígia Vieira Guedes, Aline Santos Damascena, D. Lowe, José Guilherme Vartanian, S.N. Rogers, Luiz Paulo Kowalski,
Summary Objective: The purpose of this study was to translate, culturally validate and evaluate the Patients Concerns Inventory - Head and Neck (PCI-H&N) in a consecutive series of Brazilian patients. Method: This study included adult patients treated for upper aerodigestive tract (UADT) cancer. The translation and cultural adaptation of the PCI-H&N followed internationally accepted guidelines and included a pretest sample of patients that completed the first Brazilian Portuguese version of ...
Tópico(s): Patient-Provider Communication in Healthcare
2017 - Brazilian Medical Association | Revista da Associação Médica Brasileira