Produção Nacional
Revisado por pares
Fabiano Barbieri Gonzaga, Lescy Romulo Braga, Alexandre Pimentel Sampaio, Thiago de Souza Martins, Charles Giovani de Oliveira, Raquel Moraes dos Santos Pacheco,
Tópico(s): Cultural Heritage Materials Analysis
2017 - Springer Science+Business Media | Analytical and Bioanalytical Chemistry
Produção Nacional
Revisado por pares
Rodrigo Ribeiro de Oliveira, Conceição S. Martins, Yuri R. Rocha, Allysson B. R. Braga, Rômulo Medina de Mattos, Fábio Hecht, Gerly Anne de Castro Brito, Luiz Eurico Nasciutti,
This study aims to demonstrate how the state of chronic hyperglycemia from experimental Diabetes Mellitus can influence the homeostatic imbalance of tendons and, consequently, lead to the characteristics of tendinopathy. Twenty animals were randomly divided into two experimental groups: control group, consisting of healthy rats and diabetic group constituted by rats induced to Diabetes Mellitus I. After twenty-four days of the induction of Diabetes type I, the Achilles tendon were removed for morphological ...
Tópico(s): Laser Applications in Dentistry and Medicine
2013 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Hugo José Tozze, N. M. Massola, Marcos Paz Saraiva Câmara, Ricardo Giória, O. Suzuki, Kátia Regiane Brunelli, Renato Souza Braga, Rômulo F. Kobori,
Colletotrichum boninense was isolated from pepper (Capsicum annuum) fruits (cv. Amanda) with preharvest anthracnose symptoms collected in the Brazilian states of Rio Grande do Sul and São Paulo in July of 2005. In the field, the disease affected mature fruits and leaves with an incidence near 25%. Typical symptoms in fruits were circular, sunken lesions with orange spore masses in a dark center. Three single conidia isolates were obtained from infected fruits. When grown on potato dextrose agar at ...
Tópico(s): Banana Cultivation and Research
2008 - American Phytopathological Society | Plant Disease
Produção Nacional
Revisado por pares
Gustavo Luiz Gouvêa de Almeida, Marcelo Barbosa de Almeida, Ana Carolina Mendes dos Santos, Ângela Vargas de Mattos, Ludmila S. C. Oliveira, Rômulo C. Braga,
A 3-year-old male French Bulldog was evaluated due to recent history of intolerance to exercise and coughing. The clinical, radiographic, and echocardiographic findings were consistent with cor triatriatum sinister (CTS), a congenital heart anomaly in which the left atrium is subdivided into two compartments by an abnormal fibromuscular membrane. This defect has been rarely recognized in humans and in domestic cats. To the best of our knowledge, this is the first report of the disorder in the canine ...
Tópico(s): Congenital heart defects research
2012 - Hindawi Publishing Corporation | Case Reports in Veterinary Medicine
Produção Nacional
Revisado por pares
Xinaida Taligare Vasconcelos Lima, Rômulo Tadeu Dias de Oliveira, Fernanda Gambogi Braga, Renata Ferreira Magalhães, Ronei Luciano Mamoni, Maria Heloı́sa Souza Lima Blotta,
Chemokines may contribute to local and systemic inflammation in patients with psoriasis. Previous studies have demonstrated the importance of chemokine ligands and receptors in the recruitment of T cells into psoriatic lesional skin and synovial fluid. The aim of this study was to evaluate the levels of Th1-related chemokines in psoriasis and to investigate any association with disease severity. We quantified serum levels of CXCL9, CXCL10 and CXCL16 and the frequencies of CD4+CXCR3+ T lymphocytes ...
Tópico(s): Dermatology and Skin Diseases
2014 - Informa | Autoimmunity
Produção Nacional
Revisado por pares
Danielle Pessoa Lima, Ingrid Barros Queiroz, Alexandre Henrique Silva Carneiro, Daniela Araújo Aragão Pereira, Camila Silva Castro, Antônio Brazil Viana Júnior, Charlys Barbosa Nogueira, João Macêdo Coelho Filho, Rômulo Rebouças Lôbo, Jarbas de Sá Roriz Filho, Pedro Braga‐Neto,
Background The use of telemedicine has become a fundamental tool in healthcare in recent years, especially at times of Covid-19 pandemic. Currently, there are several telemedicine tools that are simple, inexpensive, and effective means of communication. This article aims to describe indicators of feasibility including patient recruitment, attendance, discomfort (internet connection issues and/or noncompliant patient behavior), satisfaction, and travel time and cost savings of virtual telemedicine ...
Tópico(s): Mobile Health and mHealth Applications
2022 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Paulo R. O. Brito, Cristhian Loayza, Mário Edson Santos de Sousa, Eduardo de Magalhães Braga, Rômulo Simões Angélica, Simone Patrícia Aranha da Paz, M. A. Reis,
Tópico(s): Graphene research and applications
2021 - Springer Science+Business Media | Metals and Materials International
Produção Nacional
Revisado por pares
Flávia Suelen de Oliveira Pereira, Flavio A. R. Barbosa, Rômulo Farias Santos Canto, Cristiane Lucchese, Simone Pinton, Antônio L. Braga, Juliano B. Azeredo, Caroline Brandão Quines, Daiana Silva Ávila,
In a previous in vitro study, dihydropyrimidinone-derived selenoesteres demonstrated antioxidant properties, metal chelators and inhibitory acetylcholinesterase (AChE) activity, making these compounds promising candidates for Alzheimer’s Disease (AD) treatment. However, these effects have yet to be demonstrated in an in vivo animal model; therefore, this study aimed to evaluate the safety and efficacy of eight selenoester compounds in a Caenorhabditis elegans model using transgenic strains for amyloid- ...
Tópico(s): Genetics, Aging, and Longevity in Model Organisms
2021 - Elsevier BV | NeuroToxicology
Produção Nacional
Revisado por pares
Flavio A. R. Barbosa, Rômulo Faria Santos Canto, Sumbal Saba, Jamal Rafique, Antônio L. Braga,
This paper describes the synthesis and evaluation of new dihydropyrimidinone (DHPM)-derived selenoesters as potential multi-targeted agents for the treatment of Alzheimer’s disease. A series of DHPM-derived selenoesters were obtained with high structural diversity through a short and modular synthetic route. The antioxidant activity was evaluated by TBARS and iron chelation assays. These compounds were also evaluated as acetylcholinesterase inhibitors (AChEi). The compounds demonstrated good antioxidant ...
Tópico(s): Synthesis and biological activity
2016 - Elsevier BV | Bioorganic & Medicinal Chemistry
Produção Nacional
Revisado por pares
Pietro Maria Chagas, Suzan Gonçalves Rosa, Marcel Henrique Marcondes Sari, Carla Elena Sartori Oliveira, Rômulo Faria Santos Canto, Sônia Cristina Almeida da Luz, Antônio L. Braga, Cristina W. Nogueira,
Tópico(s): Selenium in Biological Systems
2014 - Elsevier BV | Pharmacology Biochemistry and Behavior
Produção Nacional
Revisado por pares
Rômulo Augusto Jucá Oliveira, Ramon Campos Braga, Daniel Vila, Carlos A. Morales,
One of the major goals of the CHUVA project (Cloud processes of tHe main precipitation systems in Brazil: A contribUtion to cloud resolVing modeling and to the GPM [GlobAl Precipitation Measurement]) is to collect information about the cloud processes of the main precipitating systems over Brazil in order to evaluate and improve the quality of satellite-based precipitation estimates. Thus, this paper evaluates the performance of the Goddard Profiling Algorithm (GPROF) version 2004 for the Special Sensor ...
Tópico(s): Soil Moisture and Remote Sensing
2014 - Elsevier BV | Atmospheric Research
Produção Nacional
Revisado por pares
Franciany Braga‐Pereira, Juliano André Bogoni, Rômulo Romeu Nóbrega Alves,
Tópico(s): Evolutionary Game Theory and Cooperation
2020 - Elsevier BV | Biological Conservation
Produção Nacional
Revisado por pares
Jamal Rafique, Rômulo Faria Santos Canto, Sumbal Saba, Flavio A. R. Barbosa, Antônio L. Braga,
Organoselenium compounds are molecules with important potential therapeutic applications. Seleniumcontaining 5-membered heterocycles have emerged as an important class of biological compounds. In the past five years, several articles related to the design, synthesis and biological evaluation of these compounds have been published. These heterocycles have been applied as antioxidants, cytotoxic agents, apoptosis inducers and chemopreventors, and they possess antidepressant activity, among others. ...
Tópico(s): Organoselenium and organotellurium chemistry
2015 - Bentham Science Publishers | Current Organic Chemistry
Produção Nacional
Revisado por pares
Denilson Braga Porto, Dartagnan Pinto Guedes, Rômulo Araújo Fernandes, Felipe Fossati Reichert,
The purpose of this study was to investigate the association between self-perceived quality of life and physical activity in Brazilian older adults.We investigated 199 individuals (117 men and 82 women) aged between 60 to 70 years old, employees of a public university.Physical activity was estimated by the short version of the International Physical Activity Questionnaire (IPAQ).Self-perceived quality of life was assessed using the World Health Organization Quality of Life (WHOQOL-Bref) questionnaire ...
Tópico(s): Physical Education and Sports Studies
2012 - Desafio Singular | Motricidade
Produção Nacional
Revisado por pares
Ianna Lacerda Sampaio Braga, João Castelo-Filho, Rafael de Sousa Bezerra Pinheiro, Rodrigo Barbosa de Azevedo, Antônio Talys Ponte, Rômulo Augusto da Silveira, Pedro Braga‐Neto, Adriana Rolim Campos,
Postoperative delirium (POD) is a common disorder and its frequency varies from 15% to 25% after major elective surgery. There are few data on the incidence of POD in Brazil. Here, we sought to assess the incidence of POD following transurethral resection of the prostate (TURP) and to examine precipitating and predisposing factors associated.We performed a prospective observational study of elderly male patients undergoing TURP (N=55) in Northeast Brazil. Information on demographic, medical, cognitive ...
Tópico(s): Anesthesia and Neurotoxicity Research
2019 - Dove Medical Press | Neuropsychiatric Disease and Treatment
Produção Nacional
Revisado por pares
Franciany Braga‐Pereira, Carlos A. Peres, Rômulo Romeu Nóbrega Alves, Carmen Van-Dúnem Neto Santos,
Overhunting typically increases during and after armed conflicts, and may lead to regional-scale defaunation. The mitigation of hunting impacts is complex because, among other reasons, several intrinsic and extrinsic motivations underpin the elevated deployment of hunting practices. Here we present the first study focusing on these motivations in a post-war zone. Following persistently heavy hunting pressure during the 27-year Angolan civil war, the offtake of small to medium-bodied species has ...
Tópico(s): Zoonotic diseases and public health
2021 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Alexandre G. S. Prado, Rômulo Davi Albuquerque Andrade, Jez Willian Batista Braga, Paulo A. Z. Suarez,
Tópico(s): Chemical Thermodynamics and Molecular Structure
2011 - Springer Science+Business Media | Journal of Thermal Analysis and Calorimetry
Produção Nacional
Revisado por pares
Bruna Gerardon Batista, Daiane Flores Dalla Lana, Gustavo P. Silveira, Marcus M. Sá, Misael Ferreira, Theo V. C. Russo, Rômulo Faria Santos Canto, Flavio A. R. Barbosa, Antônio L. Braga, Taís Fernanda Andrzejewski Kaminski, Luís Flávio Souza de Oliveira, Michel Mansur Machado, William Lopes, Marilene Henning Vainstein, Mário Lettieri Teixeira, Saulo Fernandes de Andrade, Alexandre Meneghello Fuentefría,
Abstract Fusarium is an emerging opportunistic fungal pathogen that causes local or systemic infections. The successful use of a therapeutic drug or combination antifungal therapies against Fusarium spp. are compromised because reports of multidrug resistance are currently frequent. Thus, the development of new antifungal capable of combating multidrug‐resistant Fusarium strains becomes necessary. This study presents the synthesis of seven new allylic selenocyanates and their screening against Fusarium ...
Tópico(s): Selenium in Biological Systems
2017 - Wiley | ChemistrySelect
Produção Nacional
Revisado por pares
Aline Marques da Silva Braga, Elaine Keiko Fujisao, Roberto C. Verdade, Rômulo P. Paschoalato, Ricardo P. Paschoalato, Seizo Yamashita, Luiz Eduardo Betting,
Summary Objective Studies using quantitative neuroimaging have shown subtle abnormalities in patients with idiopathic generalized epilepsy ( IGE ). These findings have several locations, but the midline parasagittal structures are most commonly implicated. The cingulate cortex is related and may be involved. The objective of the current investigation was to perform a comprehensive analysis of the cingulate cortex using multiple quantitative structural neuroimaging techniques. Methods Thirty‐two patients ( ...
Tópico(s): Functional Brain Connectivity Studies
2015 - Wiley | Epilepsia
Produção Nacional
Revisado por pares
Ruth L. Quispe, Rômulo Faria Santos Canto, Michael L. Jaramillo, Flavio A. R. Barbosa, Antônio L. Braga, Andreza Fabro de, Marcelo Farina,
Tópico(s): Nitric Oxide and Endothelin Effects
2018 - Springer Science+Business Media | Molecular Neurobiology
Produção Nacional
Revisado por pares
Flavio A. R. Barbosa, Rômulo Faria Santos Canto, Kerolain Faoro Teixeira, Anacleto Silva de Souza, Aldo Sena de Oliveira, Antônio L. Braga,
Background: Alzheimer’s disease (AD) is one of the most prevalent types of dementia, affecting millions of older people worldwide. AD is stimulating efforts to develop novel molecules targeting its main features associated with a decrease in acetylcholine levels, an increase in oxidative stress and depositions of amyloid-β (Aβ) and tau protein. In this regard, selenium-containing compounds have been demonstrated as potential multi-targeted compounds in the treatment of AD. These compounds are known ...
Tópico(s): Cholinesterase and Neurodegenerative Diseases
2022 - Bentham Science Publishers | Current Medicinal Chemistry
Produção Nacional
Revisado por pares
Paola Lax, Juan C. Rondan Dueñas, Diego Ramos, Marcelo E. Doucet, Renato de Souza Braga, Rômulo Fujito Kobori,
The false root-knot nematode, Nacobbus aberrans, causes severe damage to field and greenhouse pepper crops in several localities of the American continent. No commercial peppers (Capsicum annuum) resistant to this nematode are available up to the present. Host suitability of 6 experimental and 3 commercial peppers (some of them carrying Me1 and Me7 resistance genes to Meloidogyne spp.) to two N. aberrans populations were evaluated under greenhouse experiments. None of the peppers was found to be resistant ...
Tópico(s): Legume Nitrogen Fixing Symbiosis
2015 - Elsevier BV | Crop Protection
Produção Nacional
Revisado por pares
Érika Valente de Medeiros, Márcio de Moraes, Diogo Paes da Costa, Gustavo Pereira Duda, Jenifer Sthephanie Araújo da Silva, Julyana Braga de Oliveira, José Romualdo de Sousa Lima, Rômulo Simões Cézar Menezes, Claude Hammecker,
Trichoderma spp. are an alternative to increase plant growth and as biological control agents of diseases. Biochar added to soil and Trichoderma can result in the enhancement of crop development and can aid in preventing fertilizer run-off, improving plant health, retaining soil moisture, and helping plants through drought periods. However, a knowledge gap remains regarding the combined effect of biochar and Trichoderma on soil quality and crop growth. The objective of the present study was to evaluate ...
Tópico(s): Plant-Microbe Interactions and Immunity
2020 - Academic Press | Notulae Botanicae Horti Agrobotanici Cluj-Napoca
Produção Nacional
Revisado por pares
Flavio A. R. Barbosa, Tâmila Siminski, Rômulo Faria Santos Canto, Gabriela M. Almeida, Nádia S.R.S. Mota, Fabiana Ourique, Rozangela Curi Pedrosa, Antônio L. Braga,
Novel pyrimidinic selenoureas were synthesized and evaluated against tumour and normal cell lines. Among these, the compound named 3j initially showed relevant cytotoxicity and selectivity for tumour cells. Three analogues of 3j were designed and synthesized keeping in view the structural requirements of this compound. Almost all the tested compounds displayed considerable cytotoxicity. However, 8a, one of the 3j analogues, was shown to be highly selective and cytotoxic, especially for breast carcinoma ...
Tópico(s): Organoselenium and organotellurium chemistry
2018 - Elsevier BV | European Journal of Medicinal Chemistry
Produção Nacional
Revisado por pares
Anna Karolina Martins Borges, Tacyana Pereira Ribeiro Oliveira, Ierecê L. Rosa, Franciany Braga‐Pereira, Henrique Anatole Cardoso Ramos, Luiz A. Rocha, Rômulo Romeu Nóbrega Alves,
Social media platforms have increasingly played an influential role in boosting the online wildlife trade, by providing an easily accessible way to share information, advertise specimens, and arrange sales. We investigate how the online trade in freshwater and marine fishes for ornamental purposes operates through social media in Brazil, aiming to gain an understanding of the characteristics of that trade, and of the actors operating in it. A six-month monitoring of advertisements posted on Facebook ...
Tópico(s): Ichthyology and Marine Biology
2021 - Elsevier BV | Biological Conservation
Produção Nacional
Revisado por pares
Rômulo Faria Santos Canto, Flavio A. R. Barbosa, Vanessa Nascimento, Aldo Sena de Oliveira, Inês Maria Costa Brighente, Antônio L. Braga,
We report the design, synthesis and evaluation of a series of seleno-dihydropyrimidinones as potential multi-targeted therapeutics for Alzheimer's disease.
Tópico(s): Selenium in Biological Systems
2014 - Royal Society of Chemistry | Organic & Biomolecular Chemistry
Produção Nacional
Revisado por pares
Diogo Paes da Costa, Ademir Sérgio Ferreira de Araújo, Arthur Prudêncio de Araújo Pereira, Lucas William Mendes, Rafaela Félix da França, Thallyta das Graças Espíndola da Silva, Julyana Braga de Oliveira, Jenifer Sthephanie Araujo, Gustavo Pereira Duda, Rômulo Simões Cézar Menezes, Érika Valente de Medeiros,
Soils comprise a huge fraction of the world's biodiversity, contributing to several crucial ecosystem functions. However, how the forest-to-pasture conversion impact soil bacterial diversity remains poorly understood, mainly in the Caatinga biome, the largest tropical dry forest of the world. Here, we hypothesized that forest-to-pasture conversion would shape the microbial community. Thus, the soil bacterial community was assessed using the 16S rRNA gene sequencing into the Illumina MiSeq platform. ...
Tópico(s): Conservation, Biodiversity, and Resource Management
2021 - Elsevier BV | The Science of The Total Environment
Produção Nacional
Revisado por pares
Leonardo Gomes Braga Ferreira, Robson Xavier Faria, Natiele Carla da Silva Ferreira, Rômulo José Soares‐Bezerra,
Dyes were first obtained from the extraction of plant sources in the Neolithic period to produce dyed clothes. At the beginning of the 19th century, synthetic dyes were produced to color clothes on a large scale. Other applications for synthetic dyes include the pharmaceutical and food industries, which are important interference factors in our lives and health. Herein, we analyzed the possible implications of some dyes that are already described as antagonists of purinergic receptors, including ...
Tópico(s): Nicotinic Acetylcholine Receptors Study
2016 - Hindawi Publishing Corporation | International Journal of Food Science
Produção Nacional
Revisado por pares
Vanessa Nascimento, Natasha L. Ferreira, Rômulo Faria Santos Canto, Karen Lílian Schott, Emily Pansera Waczuk, Luca Sancineto, Claudio Santi, João Batista Teixeira da Rocha, Antônio L. Braga,
The antioxidant properties of organoselenium compounds have been extensively investigated with the aim of developing new drugs, since oxidative stress is responsible for a variety of chronic human diseases. Herein, we reported the synthesis of new nitrogen-containing diselenides by a simple and efficient synthetic route. The products were obtained in good to excellent yields and their identification and characterization were achieved by NMR and HRMS techniques. The new derivatives may represent ...
Tópico(s): Free Radicals and Antioxidants
2014 - Elsevier BV | European Journal of Medicinal Chemistry
Produção Nacional
Leonardo Rodrigues de Morais, Hesaú Rômulo Braga Pinto, Leonardo Prates Leal,
O objetivo deste trabalho é analisar o processo de impeachment da ex-presidente Dilma Rousseff (PT). Para tanto, utilizamos as categorias analíticas de Pérez-Liñán (2007), em que o autor identifica quatro condições para a ocorrência de um processo de impeachment: a) crise econômica; b) escândalo político; c) indignação popular e; d) falta de apoio legislativo. Identificamos as respectivas categorias presentes em seu segundo mandato. O processo de impeachment da ex-presidente Dilma Rousseff (PT) mobilizou ...
Tópico(s): Social and Political Issues
2024 - | Direito Processo e Cidadania