Belén Abarca, Ibón Alkorta, Rafaél Ballesteros, Fernando Blanco, Mimoun Chadlaoui, José Elguero, Fatemeh Mojarrad,
An experimental (1H NMR) and theoretical (DFT) study of the ring–chain–ring isomerization of 3-(2-pyridyl)-[1,2,3]triazolo[1,5-a]pyrid-7-yl derivatives (A) into 6-{[1,2,3]triazolo[1,5-a]pyrid-3-yl}-2-pyridyl derivatives (B) has been carried out. Based on the calculations, a mechanism of several steps will be proposed. The experimental results as well as the calculations lead to the conclusion that the A–B ratio depends on the electronic properties of the substituents.
Tópico(s): Click Chemistry and Applications
2005 - Royal Society of Chemistry | Organic & Biomolecular Chemistry
Josep M. Oliva, Stéphane Humbel, J. Arturo Santaballa, Ibón Alkorta, Rafael Notario, Juan Z. Dávalos, Moisés Canle, Eduard Bernhardt, Josef Holub, Drahomı́r Hnyk,
Abstract By means of MP2 and DFT computations we predict gas‐phase acidities and liquid‐phase (MeCN) acidities of (di)carboxylic acids derived from icosahedral ortho , meta , and para ‐carboranes. For comparative purpose, we include the benzoic and phthalic acids. Substitution of benzene by a carborane cage – cage effect – strikingly increases the gas‐phase acidity (lower GA) for the (di)carboxylic acids, being the ortho isomers always the most acidic, following the order ortho ≫ meta > para . The computed GA of the ...
Tópico(s): Supramolecular Chemistry and Complexes
2018 - Wiley | ChemistrySelect
Fernando Blanco, Ibón Alkorta, José Elguero, Víctor L. Cruz, Belén Abarca, Rafaél Ballesteros,
Tópico(s): Synthesis and Biological Evaluation
2008 - Elsevier BV | Tetrahedron
Ibón Alkorta, Vicente J. Arán, E. DAVILA, José Rafael Ruiz, M. Stud,
Abstract The acid‐catalyzed cycloaddition of N ‐substituted sulfamides 1a–f with cyanogen affords 2‐substituted 4‐amino‐2,3‐dihydro‐3‐imino‐1,2,5‐thiadiazole 1,1‐dioxides 5a–f which, in turn, could be easily hydrolyzed to give the corresponding 3‐oxo derivatives 2a–f by acid treatment. Direct spectral evidence of amino – imino tautomerism in aminothiadiazole 1,1‐dioxide derivatives has been observed for the first time in compounds 5 .
Tópico(s): Synthesis and Biological Evaluation
1989 - Wiley | Liebigs Annalen der Chemie
Javier Pemán, Rafael Zaragoza, Guillermo Quindós, Miriam Alkorta, María Soledad Cuétara, Juan J. Camarena, Paula Ramírez, María-José Giménez, Estrella Martín‐Mazuelos, María José Linares-Sicilia, José Pontón,
Poor outcomes of invasive candidiasis (IC) are associated with the difficulty in establishing the microbiological diagnosis at an early stage. New scores and laboratory tests have been developed in order to make an early therapeutic intervention in an attempt to reduce the high mortality associated with invasive fungal infections. Candida albicans IFA IgG has been recently commercialized for germ tube antibody detection (CAGTA). This test provides a rapid and simple diagnosis of IC (84.4% sensitivity ...
Tópico(s): Antibiotics Pharmacokinetics and Efficacy
2011 - BioMed Central | BMC Infectious Diseases
Vicente J. Arán, José Rafael Ruiz, E. DAVILA, Ibón Alkorta, M. Stud,
Abstract The acid‐catalyzed cyclizing addition of sulfamide to cyanogen yielded 3,4‐diamino‐1,2,5‐thiadiazole 1,1‐dioxide ( 2 ), from which through amino‐exchange reactions, the substituted compounds 3, 4 , and 5 could be derived. The unsubstituted amino groups of compounds 2 and 3 were easily hydrolyzed by basic treatment; the former afforded the 4‐amino‐3‐oxothiadiazole 8 or the dipotassium salt 6 depending on the conditions, and the latter, 4‐amino‐3‐oxo‐1,2,5‐thiadiazoles 1 . Alternative syntheses of ...
Tópico(s): Synthesis and Reactions of Organic Compounds
1988 - Wiley | Liebigs Annalen der Chemie
J.‐L. M. Abboud, Ibón Alkorta, Juan Z. Dávalos, J. Gál, Marta Herreros, Pierre‐Charles Maria, Otília Mó, Marı́a Teresa Molina, Rafael Notario, Manuel Yáñez,
Fourier Transform Ion Cyclotron Resonance Mass Spectrometry (FT ICR) has revealed the existence of the P4Li+ ion as a stable species in the gas phase. High-level ab initio calculations show that P4Li+ appears as a "planetary system" wherein the lithium cation can easily move around the P4 moiety along paths (or "orbits") connecting the points above the middle points of the P−P edges with points above the center of the PPP faces, the movement toward the corners of the tetrahedron being the less favored. ...
Tópico(s): Advanced Frequency and Time Standards
2000 - American Chemical Society | Journal of the American Chemical Society
Borja Elguezabal, Jon Alkorta, J.M. Martı́nez-Esnaola, Rafael Soler, Estíbaliz Paños,
Many different constitutive models that describe the behaviour of metal powder during hot isostatic processes are found in literature. A quantitative comparison of these material laws shows a huge discrepancy among the different existing models. This reveals the high sensitivity of the mechanical behaviour of porous materials to the shape, arrangement and distribution of particles and pores. In order to clarify these discrepancies, the compaction behaviour under high temperature hydrostatic loads ...
Tópico(s): Aluminum Alloys Composites Properties
2020 - Elsevier BV | Procedia Manufacturing
José‐Luis M. Abboud, Concepción Foces‐Foces, Rafael Notario, Ростислав Е. Трифонов, Anna P. Volovodenko, В. А. Островский, Ibón Alkorta, José Elguero,
The gas-phase and aqueous basicities of six 1,2,3-triazoles have been determined, the former by FT-ICR and the latter by spectrophotometry and 1H NMR. The gas-phase experiments agree very well with the Gibbs free energies calculated at the B3LYP/6-31G* level. In contrast, only semiquantitative ascertainments are possible when basicities in the gas phase and in solution are compared. It is possible, with the aid of calculations, to obtain a complete picture of the complex equilibria involved in C- ...
Tópico(s): Synthesis and Characterization of Heterocyclic Compounds
2001 - Wiley | European Journal of Organic Chemistry
José‐Luis M. Abboud, Rafael Notario, Manuel Yáñez, Otília Mó, Robert Flammang, Nadine Jagerovic, Ibón Alkorta, José Elguero,
Protonated 3- and 4-nitropyrazoles were subject to collisional activation and neutralization–reionization mass spectrometric studies using a large scale tandem mass spectrometer. The gas phase basicities of 2- and 4-nitroimidazoles were determined by means of Fourier transform ion cyclotron resonance spectroscopy. These and other neutral and protonated molecules were studied by ab initio methods up to and including the CCSD(T)/6–31 + G* level. This information was used to assess the site of protonation ...
Tópico(s): Energetic Materials and Combustion
1999 - Wiley | Journal of Physical Organic Chemistry
Rafael Ballesteros‐Garrido, Fernando Blanco, Rafaél Ballesteros, Frédéric R. Leroux, Belén Abarca, Françoise Colobert, Ibón Alkorta, José Elguero,
Abstract In the course of the synthesis of new fluorophores for molecular recognition an experimental ( 1 H NMR) and theoretical (DFT) study of the ring‐chain isomerism of 3‐(pyridin‐2‐yl)[1,2,3]triazolo[1,5‐ a ]quinoline derivatives ( A ) into 2‐([1,2,3]triazolo[1,5‐ a ]pyridin‐3‐yl)quinoline derivatives ( B ) has been carried out. The rearrangement is influenced by steric and electronic effects of the substituents present on the quinoline ring. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
Tópico(s): Click Chemistry and Applications
2009 - Wiley | European Journal of Organic Chemistry
Catarina Maia, Noemí Puig, María‐Teresa Cedena, Ibai Goicoechea, Rafael Valdés‐Mas, Iria Vázquez, Carmen Chillón, Paula Aguirre‐Ruiz, Sarai Sarvide, Francisco Javier Gracia-Aznárez, Gorka Alkorta‐Aranburu, Marı́a José Calasanz, Ramón García‐Sánz, Marcos González, Norma C. Gutiérrez, Joaquín Martínez‐López, José J. Pérez, Juana Merino, Cristina Moreno, Leire Burgos, Diego Alignani, Cirino Botta, Felipe Prósper, Sergio Matarraz, Alberto Órfão, Albert Oriol, Ana-Isabel Teruel, Raquel de Paz, Felipe de Arriba, Miguel‐Teodoro Hernández, Luis Palomera, Rafael Martínez, Laura Rosiñol, María‐Victoria Mateos, Juan José Lahuerta, Joan Bladé, Jesús F. San Miguel, Bruno Paiva,
Abstract Risk of developing myelodysplastic syndrome (MDS) is significantly increased in both multiple myeloma (MM) and monoclonal gammopathy of undetermined significance, suggesting that it is therapy independent. However, the incidence and sequelae of dysplastic hematopoiesis at diagnosis are unknown. Here, we used multidimensional flow cytometry (MFC) to prospectively screen for the presence of MDS-associated phenotypic alterations (MDS-PA) in the bone marrow of 285 patients with MM enrolled in the ...
Tópico(s): Myeloproliferative Neoplasms: Diagnosis and Treatment
2020 - Elsevier BV | Blood
Eider Alkorta Elorza, Rafael Leonisio,
A la luz del procés en Cataluña, han sido muchos los trabajos que han tratado de analizar qué factores explican el independentismo en esa comunidad. En el caso vasco, por el contrario, existe un vacío en la literatura académica que este artículo pretende cubrir. Hasta ahora, han prevalecido los análisis clásicos que consideraban los ejes identitarios/ étnicos como claves para el análisis del movimiento independentista en el País Vasco. En este trabajo, sin embargo, hemos querido ir más allá y analizar ...
Tópico(s): Political Systems and Governance
2019 - Centro de Investigaciones Sociológicas | Revista Española de Investigaciones Sociológicas
Borja Elguezabal, J.M. Martı́nez-Esnaola, Rafael Soler, Estíbaliz Paños, Jon Alkorta,
The prediction of the distortions during Near-Net-Shape Hot Isostatic Pressing (NNS-HIP) is an intrinsic multiscale problem where the local interactions among particles determine the macroscopic distortions taking place during the sintering and densification of a component. In this work, a multiscale approach is proposed to solve this problem. In particular, a viscoplastic constitutive model capable of predicting macroscopic contractions during a HIP process with high accuracy has been developed, ...
Tópico(s): Injection Molding Process and Properties
2023 - Elsevier BV | Powder Technology
M. Merino Hernández, J. Aranguren Castro, Maite Callén Blecua, J. Elorz Lambarri, A. Etxeberria Agirre, Juan Bautista Gáldiz Iturri, I. Irízar Aranburu, I. Lekue Alkorta, Miguel Ángel Lizarraga Azparren, M. Maeztu López de Alda, M.aL. Marqués González, A. Martínez González, Molina Hernández, J.M. Merino Nazábal, Rafael Rotaeche del Campo, M. Villar Álvarez,
aMedico de Familia. Hospital Donostia. Guipuzcoa. bMedico de Familia. Centro de Salud Lutxana. Vizcaya. cPediatra. Centro de Salud Bidebieta. Guipuzcoa. dPediatra. Seccion de Neumologia Pediatrica. Hospital de Cruces. Vizcaya. eFarmaceutica de Atencion Primaria. Guipuzcoa. fNeumologo. Hospital de Cruces. Vizcaya. gMedico de Familia. Centro de Salud Idiazabal. Guipuzcoa. hFarmaceutica de Atencion Primaria. Vizcaya. iPediatra. Centro de Salud Erandio. Vizcaya. jEnfermera. Centro de Salud Lutxana. ...
Tópico(s): Chronic Obstructive Pulmonary Disease (COPD) Research
2006 - Elsevier BV | Anales de Pediatría
Rafael Ballesteros‐Garrido, L. Bonnafoux, Fernando Blanco, Rafaél Ballesteros, Frédéric R. Leroux, Belén Abarca, Françoise Colobert, Ibón Alkorta, José Elguero,
A series of new triazolopyridine-based phosphines has been prepared. These compounds revealed unexpected spectroscopic patterns. In particular, the NMR spectra are highly dependent on the relative conformational preference of the phosphine substituent at C7. Here, we report on their complete NMR analysis, X-ray structures and DFT calculations that confirm the particular arrangement of the phosphorus lone pair orbital related to the substituent pattern of the chosen phosphine.
Tópico(s): Synthesis and biological activity
2010 - Royal Society of Chemistry | Dalton Transactions
Juan Manuel Rosa-Rosa, Isabel Cuenca, Alejandro Medina, Iria Vázquez, Andrea Sánchez-delaCruz, Natalia Buenache, Ricardo Sánchez, Cristina Jiménez, Laura Rosiñol, Norma C. Gutiérrez, Yanira Ruiz‐Heredia, Santiago Barrio, Albert Oriol, María-Luisa Martín-Ramos, María‐Jesús Blanchard, Rosa Ayala, Rafael Ríos, Anna Sureda, Miguel‐Teodoro Hernández, Javier de la Rubia, Gorka Alkorta‐Aranburu, Xabier Agirre, Joan Bladé, María‐Victoria Mateos, Juan José Lahuerta, Jesús F. San Miguel, Marı́a José Calasanz, Ramón García‐Sánz, Joaquín Martínez‐López,
Next-generation sequencing (NGS) has greatly improved our ability to detect the genomic aberrations occurring in multiple myeloma (MM); however, its transfer to routine clinical labs and its validation in clinical trials remains to be established. We designed a capture-based NGS targeted panel to identify, in a single assay, known genetic alterations for the prognostic stratification of MM. The NGS panel was designed for the simultaneous study of single nucleotide and copy number variations, insertions ...
Tópico(s): Glycosylation and Glycoproteins Research
2022 - Multidisciplinary Digital Publishing Institute | Cancers
Belén Abarca, Rafaél Ballesteros, Rosa Adam, Rafael Ballesteros‐Garrido, Frédéric R. Leroux, Françoise Colobert, Ibón Alkorta, José Elguero,
A dynamic 1H NMR study, together with DFT calculations, of bis-([1,2,3]triazolo)[1,5-a:5′,1′-k][1,10]phenanthroline 2 has allowed to identify the ring and open forms of a new example of ring/chain tautomerism, as well as their interconversion barriers (ring/ring and ring/open). The barrier of the exchange process between the chain forms and the ring form was found higher than the ‘racemization’ process in the closed form, so the ring opening does not contribute to the ‘racemization’. The di-1,10-methyl ...
Tópico(s): Photochromic and Fluorescence Chemistry
2014 - Elsevier BV | Tetrahedron
Isabel Cuenca, Alejandro Medina, Laura Rosiñol, Iria Vázquez, Ricardo Sánchez, Norma C. Gutiérrez, Yanira Ruiz‐Heredia, Santiago Barrio, Albert Oriol, Maria Luisa Martin-Ramos, Manuela Fernández-Guijarro, María Jesús Blanchard, Rafael Ríos, Anna Sureda, Miguel‐Teodoro Hernández, Javier de la Rubia, Gorka Alkorta‐Aranburu, Xabier Agirre, Gonzalo R. Ordóñez, Rafael Valdés‐Mas, María‐Victoria Mateos, Joan Bladé Creixenti, Juan José Lahuerta, Jesús F. San Miguel, Marı́a José Calasanz, Ramón García‐Sánz, Joaquín Martínez‐López,
Introduction Multiple Myeloma (MM) is a heterogeneous disease with a complex clonal and subclonal architecture with few recurrent mutations. The arrival of next-generation sequencing (NGS) has allowed us to have a deeper understanding of the disease. Due to that complexity and the low recurrence of "driver" mutations, the study of general mutational profile, copy number variation (CNV) and translocations is crucial to make an accurate diagnosis and prognosis. For that reason, a clinically validated ...
Tópico(s): Cancer Genomics and Diagnostics
2020 - Elsevier BV | Blood
Carmen Ramı́rez de Arellano, Rosa Adam, Rafael Ballesteros‐Garrido, Belén Abarca, Rafaél Ballesteros, Ibón Alkorta, José Elguero, Emilio Escrivá,
Correction for ‘A C(π-hole)⋯Cl–Zn tetrel interaction driving a metal–organic supramolecular assembly’ by Carmen Ramírez de Arellano et al. , CrystEngComm , 2020, 22 , 6979–6982, DOI: 10.1039/D0CE01272F.
Tópico(s): Dendrimers and Hyperbranched Polymers
2020 - Royal Society of Chemistry | CrystEngComm
Molina Hernández, J. Aranguren Castro, M. Callén Blecua, J. Elorz Lambarri, A. Etxeberria Agirre, Juan Bautista Gáldiz Iturri, I. Irízar Aranburu, I. Lekue Alkorta, Miguel Ángel Lizarraga Azparren, M. Maeztu López de Alda, M.aL. Marqués González, A. Martínez González, Molina Hernández, J.M. Merino Nazábal, Rafael Rotaeche del Campo, M. Villar Álvarez,
Tópico(s): Chronic Obstructive Pulmonary Disease (COPD) Research
2006 - Elsevier BV | Anales de Pediatría
... 10.1111/j.1365-2656.2004.00784.xI. Alkorta, I. Albizu, I. Amezaga, M. Onaindia, V. Buchner, ...
Tópico(s): Evolutionary Game Theory and Cooperation
1983 - University of Chicago Press | The American Naturalist
Ibón Alkorta, Vicente J. Arán, E. DAVILA, José Rafael Ruiz, M. Stud,
ChemInformVolume 21, Issue 7 Heterocyclic Compounds ChemInform Abstract: Reactivity of Cyanogen Towards N-Substituted Sulfamides: Synthesis of 1,2,5-Thiadiazole 1,1-Dioxide Derivatives. I. ALKORTA, I. ALKORTA Inst. Quim. Med., CSIC, E-28006 Madrid, SpainSearch for more papers by this authorV. J. ARAN, V. J. ARAN Inst. Quim. Med., CSIC, E-28006 Madrid, SpainSearch for more papers by this authorE. DAVILA, E. DAVILA Inst. Quim. Med., CSIC, E-28006 Madrid, SpainSearch for more papers by this authorJ. ...
Tópico(s): Sulfur-Based Synthesis Techniques
1990 - Wiley | ChemInform
Carmen Marina Meseguer Barros, Natalia Alzueta, Rita Sainz de Rozas Aparicio, Rafael Aguilella Vizcaíno, L López Esteban, S Anaya Ordóñez, Itxasne Lekue Alkorta, Salvadora Martín Suances, Jorge Ignacio Jiménez Arce, Maite Fernández Vicente, Yolanda Borrego Izquierdo, Raquel Prieto Sánchez, Silvia Casado Casuso, Rosa Madridejos, Carmen Marquina Verde, Rosa Tomás Sanz, M Oro Fernandez, Sara Gallardo Borge, Eva López, María Belén Pina Gadea, Mercedes Pereira Pía, María Victoria Maestre‐Sánchez, Esther Ribes-Murillo, Constanza Gómez de Oña, María Jesús Lallana, Concepción Celaya Lecea, María Ana Prado Prieto, Aranzazu Aranguez Ruiz, Vicente Olmo Quintana, Noemí Villén Romero, Carolina Payá Giner, Ángeles Lloret Callejo, Alvaro Fernández Ferreiro, Blanca Basagoiti Carreño, Ana Aurelia Iglesias Iglesias, Antonio Martín Alonso, Ana Díez Alcántara, Esther Marco Tejón, Marta Lestón Vázquez, Ma Ángeles Ariza Copado, Marta Aparicio, Belén Escudero Vilaplana, Marisa Nicieza, G Picazo Sanchiz, Genma María Silva Riádigos, Lucía Jamart Sánchez, Ángel García Álvarez, Antonio García Bonilla, Rafael Herrero Delicado, Virginia Arroyo Pineda, Belén de la Hija, Amelia Troncoso Mariño, Isabel Tofiño González, Mónica Susana Mateu García, Pablo García Vázquez, Joaquín Pérez Martín, Rocío Fernández‐Urrusuno,
The aim of this study was to know the prevalence and severity of COVID-19 in patients treated with long-term macrolides and to describe the factors associated with worse outcomes. A cross-sectional study was conducted in Primary Care setting. Patients with macrolides dispensed continuously from 1 October 2019 to 31 March 2020, were considered. Main outcome: diagnosis of coronavirus disease-19 (COVID-19). Secondary outcomes: symptoms, severity, characteristics of patients, comorbidities, concomitant ...
Tópico(s): COVID-19 and healthcare impacts
2021 - Multidisciplinary Digital Publishing Institute | Antibiotics
Vicente J. Arán, José Rafael Ruiz, E. DAVILA, Ibón Alkorta, M. Stud,
Abstract The acid‐catalyzed cyclization of sulfamide (I) and cyanogen (II) yields the thiadiazole dioxide (IIIa), whose derivatives (IIIb) and (IIIc) are obtained by amino‐exchange reactions.
Tópico(s): Synthesis and Reactions of Organic Compounds
1988 - Wiley | ChemInform
José‐Luis M. Abboud, Concepción Foces‐Foces, Rafael Notario, Ростислав Е. Трифонов, Anna P. Volovodenko, В. А. Островский, Ibón Alkorta, José Elguero,
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Tópico(s): Synthesis and Characterization of Heterocyclic Compounds
2002 - Wiley | ChemInform
José‐Luis M. Abboud, Rafael Notario, Manuel Yáñez, Otília Mó, Robert Flammang, Nadine Jagerovic, Ibón Alkorta, José Elguero,
Protonated 3- and 4-nitropyrazoles were subject to collisional activation and neutralization–reionization mass spectrometric studies using a large scale tandem mass spectrometer. The gas phase basicities of 2- and 4-nitroimidazoles were determined by means of Fourier transform ion cyclotron resonance spectroscopy. These and other neutral and protonated molecules were studied by ab initio methods up to and including the CCSD(T)/6–31 + G* level. This information was used to assess the site of protonation ...
Tópico(s): Chemical Thermodynamics and Molecular Structure
1999 - Wiley | Journal of Physical Organic Chemistry
Fabian Bebensee, Kira Welter, Greta Heydenrych,
... University of Hong Kong Hong Kong Members Ibon Alkorta* Instituto de Quimica Medica Spain Vincenzo Amendola* Universita ... Korea Anton Middelberg University of Adelaide Australia Alvaro Rafael Muñoz-Castro* Universidad Autonoma de Chile Chile Michel ...
Tópico(s): History and advancements in chemistry
2018 - Wiley | ChemPhysChem
José Manuel Ramia, Elena Martín‐Pérez, Ignasi Poves, Joan Fabregat-Prous, Javier Larrea y Olea, Francisco Sánchez‐Bueno, Francisco Botello-Martínez, Javier Briceño, Alberto Miyar-de León, M. Serradilla, Ángel Moya‐Herraiz, Joan Fabregat Prous, Lluís Secanella, Javier Larrea y Olea, F.S Bueno, Francisco Botello Martínez, Javier Briceño, Alberto Miyar-de León, M. Serradilla, Alejandro Serrablo, Joana Ferrer, Santiago Sánchez-Cabús, Miguel Ángel Gómez Bravo, Javier Padillo-Ruíz, L. Blanco, J. Balcells, Esteban Cugat, Maribel García Domingo, Luis Muñoz‐Bellvís, Maria Dolores Perez Diaz, Julio Santoyo Santoyo, Belinda Sánchez Pérez, T. Villegas, Silvino Pacho, Luis Díez Valladares, J. Rebollar, Miguel Ángel Suárez Muñóz, Elías Domínguez, Elena Martín‐Pérez, Laia Falgueras, Ignasi Poves, Vicenç Artigas, Luís Sabater, Agustín García Gil, José Ignacio Miota de Llama, Gerardo Manzanet, José Carlos Rodríguez Pino, Juan Carlos Rodríguez Sanjuán, Fèlix Lluı́s, Fabio Ausania, Maialen Alkorta Zuloaga, Alfredo Escartín, Manel Salas, Carlos Domingo del Pozo, Enrique Artigues Sánchez de Rojas, José Antonio Barreras Mateos, José María Fernández Cebrián, Beatriz Pérez Cabrera, David Padilla, Alfonso Sanjuánbenito, Ignacio Iturburu Belmonte, Natalia Bejarano, Francisco G. Borobia, Pablo Toral Guinea, A. Lopez Marcano, Francisco Asencio Arana, Evaristo Varó, Rafael José Esteban de la Rosa, Juan Laaa Blas, José M. Jover Navalón, Cristina Fernández Martínez, E. Daban Collado, Antonio Calvo, J. C. Vicens, Jorge del Romero, Josep M. Badía, Raquel Sánchez‐Santos, Ricardo de Miguel Ibáñez, Fernando Pardoc, Carlos Francos von Hunefeld, Fernando Pereira, Francisco Garcı́a-Molina, Ignacio Rodríguez Prieto, Alfredo Alonso Poza, Carlos Gilsanz, Jose Miguel Martínez Albert, Miguel A. Morcillo, Sagrario Martínez Cortijo, José Martín Fernández, Jesús Baquedano, J. García i Castell, Javier Aguiló, Juan Carlos Guerrero Bernal,
La pancreatectomía total (PT) es una intervención infrecuente, con unas indicaciones no claramente definidas y unos resultados postoperatorios no estandarizados. Presentamos un estudio multicéntrico nacional sobre PT y una comparación con la literatura existente. Estudio prospectivo observacional realizado mediante el registro nacional de pacientes operados de duodenopancreatectomía cefálica y PT realizadas por cualquier indicación durante el periodo comprendido entre el 1 enero y el 31 diciembre ...
Tópico(s): Neuroendocrine Tumor Research Advances
2019 - Elsevier BV | Cirugía Española
José Manuel Ramia, Elena Martín‐Pérez, Ignasi Poves, Joan Fabregat-Prous, Javier Larrea y Olea, Francisco Sánchez‐Bueno, Francisco Botello-Martínez, Javier Briceño, Alberto Miyar-de León, M. Serradilla, Ángel Moya‐Herraiz, Joan Fabregat Prous, Lluís Secanella, Javier Larrea, Olea, F.S Bueno, Francisco Botello Martínez, Javier Briceño, Alberto Miyar-de León, M. Serradilla, Alejandro Serrablo, Joana Ferrer, Santiago Sánchez-Cabús, Miguel Ángel Gómez Bravo, Javier Padillo-Ruíz, L. Blanco, J. Balcells, Esteban Cugat, Maribel García Domingo, Luis Muñoz‐Bellvís, Maria Dolores Perez Diaz, Julio Santoyo Santoyo, Belinda Sánchez Pérez, T. Villegas, Silvino Pacho, Luis Díez Valladares, J. Rebollar, Miguel Ángel Suárez Muñóz, Elías Domínguez, Elena Martín‐Pérez, Laia Falgueras, Ignasi Poves, Vicenç Artigas, Luís Sabater, Agustín García Gil, José Ignacio Miota de Llama, Gerardo Manzanet, José Carlos Rodríguez Pino, Juan Carlos Rodríguez Sanjuán, Fèlix Lluı́s, Fabio Ausania, Maialen Alkorta Zuloaga, Alfredo Escartín, Manel Salas, Carlos Domingo del Pozo, Enrique Artigues Sánchez de Rojas, José Antonio Barreras Mateos, José María Fernández Cebrián, Beatriz Pérez Cabrera, David Padilla, Alfonso Sanjuánbenito, Ignacio Iturburu Belmonte, Natalia Bejarano, Francisco G. Borobia, Pablo Toral Guinea, A. Lopez Marcano, Francisco Asencio Arana, Evaristo Varó, Rafael Esteban, Juan Luís Blas, José M. Jover Navalón, Cristina Fernández Martínez, E. Daban Collado, Antonio Calvo, J. C. Vicens, Jorge del Romero, Josep M. Badía, Raquel Sánchez‐Santos, Ricardo de Miguel Ibáñez, Fernando Pardoc, Carlos Francos von Hunefeld, Fernando Pereira, Francisco Garcı́a-Molina, Ignacio Rodríguez Prieto, Alfredo Alonso Poza, Carlos Gilsanz, Jose Miguel Martínez Albert, Miguel A. Morcillo, Sagrario Martínez Cortijo, José Martín Fernández, Jesús Baquedano, J. García i Castell, Javier Aguiló, Juan Carlos Guerrero Bernal,
Total pancreatectomy (TP) is an uncommon operation, with indications that have not been clearly defined and non-standardized postoperative results. We present a national multicentric study on TP and a comparison with the existing literature. A prospective observational study using data from the national registry of patients after pancreaticoduodenectomy and TP performed for any indication during the study period: January 1–December 31, 2015. 1016 patients were included from 73 hospitals, 112 of whom ...
Tópico(s): Gallbladder and Bile Duct Disorders
2019 - Elsevier BV | Cirugía Española (English Edition)