Book.
0000 - Gale Group | World Scholar Latin America
Produção Nacional
Revisado por pares
Mozarte Santos Santana, Rafael Pereira Alves, Lucas Santos Santana, Mateus A. Gonçalves, Mário César Guerreiro,
The hydrothermal carbonization process is a suitable process for the conversion of potentially harmful lignocellulosic waste into hydrochars. Defective coffee beans were the precursor raw material for hydrochar synthesis. Reactions were performed in a high-pressure reactor at 150, 200, and 250 °C, in autogenous pressure, for 40 min. Hydrochars were recovered by filtration and characterized by energy dispersive X-ray fluorescence spectroscopy, UV-Vis spectrophotometry, attenuated total reflection ...
Tópico(s): Thermochemical Biomass Conversion Processes
2021 - Elsevier BV | Journal of Environmental Management
Produção Nacional
Revisado por pares
Rafael Rodrigues Lima, Luana N. S. Santana, Rafael M. Fernandes, Elder Monteiro do Nascimento, Ana Carolina Alves de Oliveira, Luanna Melo Pereira Fernandes, Enio Mauricio N. dos Santos, Patrycy Assis N. Tavares, Ijair Rogério Santos, Adriano Gimarães-Santos, Walace Gomes‐Leal,
Stroke is a leading cause of death and neurological disability worldwide and striatal ischemic stroke is frequent in humans due to obstruction of middle cerebral artery. Several pathological events underlie damage progression and a comprehensive description of the pathological features following experimental stroke in both acute and chronic survival times is a necessary step for further functional studies. Here, we explored the patterns of microglial activation, astrocytosis, oligodendrocyte damage, ...
Tópico(s): Nerve injury and regeneration
2016 - Hindawi Publishing Corporation | Oxidative Medicine and Cellular Longevity
Produção Nacional
Revisado por pares
Breno Barros de Santana, Rafael Antonio Nascimento Ramos, Marília de Andrade Santana, Lêucio Câmara Alves, Gílcia Aparecida de Carvalho,
The synthetic pyrethroids and their associations have been widely used for controlling Rhipicephalus (Boophilus) microplus. The frequent use of acaricides has been inducing the development of resistance in the tick populations. The aim of this study was to assess the susceptibility of R. (B.) microplus populations to pyrethroids and their associations in the region of Garanhuns, Pernambuco, Brazil. In addition, the level of information among farm owners regarding tick control measures was investigated. ...
Tópico(s): Insect Pest Control Strategies
2013 - Colégio Brasileiro de Parasitologia Veterinaria | Revista Brasileira de Parasitologia Veterinária/Brazilian Journal of Veterinary Parasitology
Daniel Morgensztern, Neal Ready, Melissa L. Johnson, Afshin Dowlati, Noura J. Choudhury, David P. Carbone, Eric Schaefer, Susanne M. Arnold, Sonam Puri, Zofia Piotrowska, Aparna Hegde, Anne C. Chiang, Wade T. Iams, Anthony W. Tolcher, Kaname Nosaki, Toshiyuki Kozuki, Tianhong Li, Rafael Santana‐Davila, Hiroaki Akamatsu, Haruyasu Murakami, Hiroshi Yokouchi, Song Wang, Jiuhong Zha, Rui Li, Randy Robinson, Pooja Hingorani, Edwin E. Jeng, Muhammad Furqan,
Abstract Purpose: Seizure-related homolog protein 6 (SEZ6) is a novel target expressed in small cell lung cancer (SCLC). ABBV-011, a SEZ6-targeted antibody conjugated to calicheamicin, was evaluated in a phase I study (NCT03639194) in patients with relapsed/refractory SCLC. We report initial outcomes of ABBV-011 monotherapy. Patients and Methods: ABBV-011 was administered intravenously once every 3 weeks during dose escalation (0.3–2 mg/kg) and expansion. Patients with SEZ6-positive tumors (≥25% of tumor ...
Tópico(s): Peptidase Inhibition and Analysis
2024 - American Association for Cancer Research | Clinical Cancer Research
Joseph B. Hiatt, Anna-Lisa Doebley, Henry U. Arnold, Mohamed Adil, Holly Sandborg, Thomas Persse, Minjeong Ko, Feinan Wu, Álvaro Quintanal-Villalonga, Rafael Santana‐Davila, Keith D. Eaton, Caroline Dive, Charles M. Rudin, Anish Thomas, A. McGarry Houghton, Gavin Ha, David MacPherson,
We report an approach for cancer phenotyping based on targeted sequencing of cell-free DNA (cfDNA) for small cell lung cancer (SCLC). In SCLC, differential activation of transcription factors (TFs), such as ASCL1, NEUROD1, POU2F3, and REST defines molecular subtypes. We designed a targeted capture panel that identifies chromatin organization signatures at 1535 TF binding sites and 13,240 gene transcription start sites and detects exonic mutations in 842 genes. Sequencing of cfDNA from SCLC patient- ...
Tópico(s): RNA modifications and cancer
2024 - American Association for the Advancement of Science | Science Advances
Produção Nacional
Revisado por pares
Cesar Manchein, Luana Santana, Rafael M. da Silva, Marcus W. Beims,
The nonlinear dynamics of a FitzHugh–Nagumo (FHN) neuron driven by an oscillating current and perturbed by a Gaussian noise signal with different intensities D is investigated. In the noiseless case, stable periodic structures [Arnold tongues (ATS), cuspidal and shrimp-shaped] are identified in the parameter space. The periods of the ATSs obey specific generating and recurrence rules and are organized according to linear Diophantine equations responsible for bifurcation cascades. While for small values ...
Tópico(s): Neural dynamics and brain function
2022 - American Institute of Physics | Chaos An Interdisciplinary Journal of Nonlinear Science
Produção Nacional
Revisado por pares
Mattheus Augusto Siscotto TOBIAS, Bruna P Nogueira, Marcos Cleison Silva Santana, Rafael G Pires, João Paulo Papa, Paulo S S Santos,
Oral cancer could be prevented. The primary strategy is based on prevention. Most patients with oral cancer present to the hospital network with advanced staging and a low chance of cure. This condition may be related to physicians' difficulty of making an early diagnosis. With the advancement of information technology, artificial intelligence (AI) holds great promise in terms of assisting in diagnosis. Few machine learning algorithms have been developed for this purpose to date. In this paper, we ...
Tópico(s): Head and Neck Cancer Studies
2022 - Elsevier BV | Oral Oncology
Produção Nacional
Revisado por pares
Luana Santana, Rafael M. da Silva, Holokx A. Albuquerque, Cesar Manchein,
We analyze the existence of chaotic and regular dynamics, transient chaos phenomenon, and multistability in the parameter space of two electrically interacting FitzHugh–Nagumo (FHN) neurons. By using extensive numerical experiments to investigate the particular organization between periodic and chaotic domains in the parameter space, we obtained three important findings: (i) there are self-organized generic stable periodic structures along specific directions immersed in a chaotic portion of the parameter ...
Tópico(s): Nonlinear Dynamics and Pattern Formation
2021 - American Institute of Physics | Chaos An Interdisciplinary Journal of Nonlinear Science
Produção Nacional
Revisado por pares
Lucas Santos Santana, Gabriel Araújo e Silva Ferraz, João Paulo Barreto Cunha, Mozarte Santos Santana, Rafael de Oliveira Faria, Diego Bedin Marin, Giuseppe Rossi, Leonardo Conti, Marco Vieri, Daniele Sarri,
Mechanized operations on terrain slopes can still lead to considerable errors in the alignment and distribution of plants. Knowing slope interference in semi-mechanized planting quality can contribute to precision improvement in decision making, mainly in regions with high slope. This study evaluates the quality of semi-mechanized coffee planting in different land slopes using a remotely piloted aircraft (RPA) and statistical process control (SPC). In a commercial coffee plantation, aerial images ...
Tópico(s): Tree Root and Stability Studies
2021 - Multidisciplinary Digital Publishing Institute | Agronomy
Produção Nacional
Revisado por pares
Romário Oliveira de Santana, Rafael Coll Delgado, Alexandre Schiavetti,
Tópico(s): Remote Sensing and LiDAR Applications
2021 - Elsevier BV | Journal of Environmental Management
Produção Nacional
Revisado por pares
Felipe de Medeiros Magalhães, Mariana L. Lyra, Thiago Ribeiro de Carvalho, Diego Baldo, Francisco Brusquetti, Pamela Mariana Burella, Guarino Rinaldi Colli, Marcelo Gehara, Ariovaldo A. Giaretta, Célio F. B. Haddad, José A. Langone, Javier López, Marcelo Felgueiras Napoli, Diego José Santana, Rafael O. de Sá, Adrian Antonio Garda,
The Leptodactylus latrans species group currently comprises eight medium- to large-sized frog species with a convoluted taxonomic history, particularly related to the specific limits of the L. latrans complex, and the species pair Leptodactylus chaquensis–Leptodactylus macrosternum. Their homogeneous external morphology and continental geographic distribution in South America have posed severe limitations to a comprehensive review, such that taxonomic consensus and species limits remain uncertain. ...
Tópico(s): Lepidoptera: Biology and Taxonomy
2020 - Illinois Natural History Survey | Herpetological Monographs
Produção Nacional
Romário Oliveira de Santana, Rafael Coll Delgado, Alexandre Schiavetti,
The Brazilian Atlantic Forest is one of 34 biodiversity hotspots worldwide and is considered one of the five most important for conservation. In this context, the present study examines meteorological and biophysical variables from 2001 to 2016, on a monthly scale, to describe the past, present and future of vegetation in the Central Atlantic Forest Corridor for different land use and land cover categories. The Autoregressive Integrated Moving Average model was applied to the Enhanced Vegetation ...
Tópico(s): Fire effects on ecosystems
2020 - Elsevier BV | Remote Sensing Applications Society and Environment
Produção Nacional
Revisado por pares
Fernanda Paula Roncon Santana, Rafael Carlos da Silva, Vitor Ponci, Aruanã J.M.C.R. Pinheiro, Clarice Rosa Olivo, Luciana C. Caperuto, Fernanda M. Arantes-Costa, Samuel Rangel Cláudio, Daniel Araki Ribeiro, Iolanda de Fátima Lopes Calvo Tibério, Lídio Gonçãlves Lima Neto, João Henrique G. Lago, Carla M. Prado,
Eugenol, a common phenylpropanoid derivative found in different plant species, has well-described anti-inflammatory effects associated with the development of occupational hypersensitive asthma. Dehydrodieugenol, a dimeric eugenol derivative, exhibits anti-inflammatory and antioxidant activities and can be found in the Brazilian plant species Nectandra leucantha (Lauraceae). The biological effects of dehydrodieugenol on lung inflammation remain unclear.This study aimed to investigate the effects ...
Tópico(s): Bioactive Compounds and Antitumor Agents
2020 - Elsevier BV | Biochemical Pharmacology
Mónica Santana, Rafael Morales‐Sánchez, Susana Pasamar,
Despite the relevance of human resources in the management of Corporate Social Responsibility (CSR), confusion and theoretical chaos are still evident in the area. This manuscript provides a systematic review of the link between CSR and Human Resource Management (HRM), stressing the main topics along with the evolution and tendencies founded in this field. SciMAT was used to conduct a conceptual science mapping analysis based on co-word bibliographic networks. From 2006 to 2019, 194 documents were ...
Tópico(s): Sustainable Supply Chain Management
2020 - Multidisciplinary Digital Publishing Institute | Sustainability
Produção Nacional
Revisado por pares
Gustavo Brunetto, Daniel José Rosa, Vítor Gabriel Ambrosini, Janaína Heinzen, Paulo Ademar Avelar Ferreira, Carlos Alberto Ceretta, Cláudio Roberto Fonsêca Sousa Soares, G. W. B. de Melo, Hilda Hildebrand Soriani, Fernando Teixeira Nicoloso, Júlia Gomes Farias, Lessandro De Conti, Lincon Oliveira Stefanello, Natielo Almeida Santana, Rafael Rosa Couto, Rodrigo Josemar Seminoti Jacques, Tadeu Luís Tiecher,
Established vineyard soils may have high copper (Cu) contents due to the ongoing foliar applications of copper-based fungicides. In viticulture, the replacement of old vineyards with new vines is common practice, however, limited by Cu excess in soil and its toxicity to young grapevines. The application of phosphorus (P) and arbuscular mycorrhizal fungi (AMF) inoculation are potential strategies to reduce Cu toxicity to young grapevines. This study aimed to assess the effects of phosphorus fertilization ...
Tópico(s): Plant Stress Responses and Tolerance
2019 - Elsevier BV | Scientia Horticulturae
Produção Nacional
Revisado por pares
Mozarte Santos Santana, Rafael Pereira Alves, Willian Miguel da Silva Borges, Elton Francisquini, Mário César Guerreiro,
This study aimed to produce and characterize hydrochars from defective coffee beans and its application as a solid fuel. Defective coffee beans were used as precursor residue for hydrochar synthesis. Reactions were run in a high-pressure reactor at temperatures of 150, 200 and 250 °C, under autogenesis pressure, for 40 min. Solid phase was recovered by filtration and characterized by CHNO-S analyzer, thermogravimetric analysis and differential scanning calorimetry. Hydrothermal carbonization temperature ...
Tópico(s): Biodiesel Production and Applications
2019 - Elsevier BV | Bioresource Technology
Produção Nacional
Revisado por pares
Fernanda Paula Roncon Santana, Rafael Carlos da Silva, Simone S. Grecco, Aruanã Joaquim Matheus Costa Rodrigues Pinheiro, Luciana C. Caperuto, Fernanda M. Arantes-Costa, Samuel Rangel Cláudio, Kelly Yoshizaki, Mariângela Macchione, Daniel Araki Ribeiro, Iolanda de Fátima Lopes Calvo Tibério, Lídio Gonçãlves Lima Neto, João Henrique G. Lago, Carla M. Prado,
Asthma allergic disease is caused by airway chronic inflammation. Some intracellular signaling pathways, such as MAPK and STAT3-SOCS3, are involved in the control of airway inflammation in asthma. The flavonoid sakuranetin demonstrated an anti-inflammatory effect in different asthma models. Our aim was to clarify how sakuranetin treatment affects MAPK and STAT3-SOCS3 pathways in a murine experimental asthma model. Mice were submitted to an asthma ovalbumin-induction protocol and were treated with ...
Tópico(s): Genomics, phytochemicals, and oxidative stress
2019 - Hindawi Publishing Corporation | Mediators of Inflammation
Virginia Hernández‐Santana, Rafael Dreux Miranda Fernandes, A. Pérez-Arcoiza, J.E. Fernández, José M. Garcı́a, Antonio Díaz-Espejo,
Carbohydrates availability, which are directly related to photosynthesis (AN), and turgor are the main determinants of fruit growth. Since stomatal conductance (gs) is the main limiting factor of AN in fruit trees in most environments, and is strongly regulated by turgor, its measurement is pivotal to understanding fruit growth dynamics. Despite its relevance, the use of gs to estimate AN faces the major limitation of being difficult to measure in an automated and continuous manner. Based on these ...
Tópico(s): Irrigation Practices and Water Management
2018 - Elsevier BV | Agricultural and Forest Meteorology
Produção Nacional
Luciana Maiara Queiroz de Santana, Rafael M. Santos, Leonardo Nogueira Matos, Hendrik Macedo,
Systems using deep neural network (DNN) have shown promising results in automatic speech recognition (ASR), where one of the biggest challenges is the recognition in noisy speech signals. We have combined two famous architectures of deep learning, the convolutional neural networks (CNN) for acoustic approach and a recurrent architecture with connectionist temporal classification (CTC) for sequential modeling, in order to decode the frames in a sequence forming a word. Experimental results show that ...
Tópico(s): Speech and Audio Processing
2018 - Institute of Electrical and Electronics Engineers | IEEE Latin America Transactions
Catarina Tomás, Emanuel Oliveira, Daniellen Cristina Ferreira Sousa, Matheus Uba Chupel, Guilherme Eustáquio Furtado, Clara Rocha, Ana Teixeira, Pedro Lopes Ferreira, C. Alves, Stefan Gisin, Elisabete Catarino, Nelma Carvalho, Tiago Coucelo, Luís Américo Silva Bonfim, Carina Silva, Débora Franco, Jesús Alcoba González, Maria Helena de Agrela Gonçalves Jardim, Rita Silva, Cristina Lavareda Baixinho, Ma Helena Presado, Ma Fátima Marques, Mário E. Cardoso, Marina Cunha, Joana Mendes, Ana Xavier, Ana Galhardo, Margarida Couto, João Frade, Carla Nunes, João R. Mesquita, María Säo José Nascimento, Guilherme Gonçalves, Conceição Castro, Alice Mártires, M. João Monteiro, Conceição Rainho, Francisco P. Caballero, Fátima M. Monago, José T. Guerrero, Rocio M. Monago, Africa P. Trigo, Milagros L. Gutierrez, Gemma M. Milanés, Mercedes G. Reina, Ana G. Villanueva, Ana S. Piñero, Isabel R. Aliseda, Francisco Buitrago Ramírez, Andrea Ribeiro, Ana Quelhas, Maria Conceição Manso, Francisco P. Caballero, José T. Guerrero, Fátima M. Monago, Rafael Brito Santos, Nuria R. Jimenez, Cristina G. Nuñez, Inmaculada Rodríguez Gómez, Ma Jose L. Fernandez, Laura A. Marquez, Ana L. Moreno, Ma Jesus Tena Huertas, Francisco Buitrago Ramírez, Daniel Seabra, Ma Céu Salvador, Luciene Muniz Braga, Pedro Parreira, Anabela Salgueiro‐Oliveira, Cristina Arreguy-Sena, Bibiana F. Oliveira, Ma Adriana Henriques, Joana Santos, Sara Lebre, Alda Marques, Clarinda Festas, Sandra Rodrigues, Andrea Ribeiro, José Lumini‐Oliveira, Ana Gabriela Figueiredo, Francisco J. Hernandez-Martinez, Liliana Campi, Ma Pino Quintana-Montesdeoca, Juan F. Jimenez-Diaz, Bienvenida C. Rodriguez-De-Vera, Alexandra Parente, Ma Augusta Mata, Ana Ma Pereira, Adília Fernandes, Manuel Brás, Ma Rosário Pinto, Pedro Parreira, Marta Lima Basto, Ana C. Rei, Lisete Mónico, Gilberta Sousa, Clementina Morna, Otília Freitas, Gregório Freitas, Ana Carolina Gomes Jardim, Rita P. Vasconcelos, Lina G. Horta, Roger dos Santos Rosa, Luís Fernando Kranz, Rita C. Nugem, Mariana Santiago Siqueira, Ronaldo Bordin, Rosiane Kniess, Josimari Telino de Lacerda, Joana Guedes, Idalina Machado, Sidalina Almeida, Adriano Zilhão, Hélder Alves, Óscar Ribeiro, Ana Paula Martins Amaral, Ana Maria Ribeiro dos Santos, Joana Monteiro, Ma Clara Rocha, Rui Cruz, Ana Paula Martins Amaral, Marina Lourenço, Ma Clara Rocha, Rui Cruz, Sandra Regina Masetto Antunes, Verónica Mendonça, Isabel Andrade, Nádia Osório, Ana Valado, Armando Caseiro, Antonio Padua y Gabriel, Anabela Correia Martins, Fernando Mendes, Lídia Cabral, Manuela Ferreira, Amadeu Gonçalves, Tatiana Durão D`Ávila Luz, Leonardo Gomes de Oliveira Luz, Raúl A. Martins, Alice Murteira Morgado, Maria da Luz Vale-Dias, Rui Porta-Nova, Tânia Cristina Malezan Fleig, Éboni Marília Reuter, Miriam Beatris Froemming, Sabrina Luciane Camara Guerreiro, Lisiane Lisbôa Carvalho, Daniel Guedelha, Pedro S. Coelho, A.T. Pereira, António Calha, Raúl Cordeiro, Ana Gonçalves, Ana Certo, Ana Cristina Araújo de Andrade Galvão, Ma Augusta Mata, Aline Welter, Elayne Crestani Pereira, Sandra Aparecida Ribeiro, Márcia Regina Kretzer, Juan-Fernando Jiménez-Díaz, Carla Jiménez-Rodríguez, Francisco-José Hernández-Martínez, Bienvenida-Del-Carmen Rodríguez-De-Vera, Alexandre Marques-Rodrigues, Patrícia Brazil Pereira Coelho, Tiago Bernardes, Alexandre de Araújo Pereira, Patrícia Sousa, João Ghizzo Filho, Nazaré Otília Nazário, Márcia Regina Kretzer, Odete Amaral, António Garrido, Nélio Veiga, Carla Nunes, Ana Rita Pedro, Carlos Pereira, António Almeia, Hélder Miguel Fernandes, Carlos Vasconcelos, Nélson Sousa, Víctor Machado Reis, M. João Monteiro, Romeu Mendes, Isabel Pinto, Tânia C. S. P. Pires, João Gama, Vera Preto, Norberto Silva, Carlos Pires Magalhães, Matilde Martins, Mafalda Duarte, Constança Paúl, Ignácio Martín, Arminda Pinheiro, Sandra Doria Xavier, J. Azevedo, E. Bento, C. Marques, M. Marques, A. Macedo, A.T. Pereira, José Pedro Almeida, António Almeida, Josiane Alves, Nélson Sousa, Francisco Saavedra, Romeu Mendes, Ana S. Maia, Michelle Teixeira Oliveira, Anderson Reis de Sousa, Paulo P. Ferreira, Luci S. Lopes, Eujcely C. Santiago, Sílvia Monteiro, Ângelo Jesus, Armanda Colaço, Antônio Ivo de Carvalho, Rita P. Silva, Agostinho Cruz, Ana Ferreira, Catarina Marques, João Paulo Figueiredo, Susana Paix�ão, Ana Ferreira, Carla Lopes, Fernando Moreira, João Paulo Figueiredo, Ana Ferreira, Diana Ribeiro, Fernando Moreira, João Paulo Figueiredo, Susana Paix�ão, Telma Fernandes, Diogo Amado, Jéssica Denise Vieira Leal, Marcelo Costa Velho Mendes de Azevedo, Sónia Ramalho, Catarina Mangas, Jaime Ribeiro, Rita Maria de Abreu Gonçalves, Amélia Fernandes Nunes, Ana Rita Tuna, Carlos Martins, Henriqueta D. Forte, Cláudia Costa, José António Tenedório, Paula Santana, José Augusto Andrade, Joana Pinto, C. Campofiorito, S. C. Nunes, Ana Sofia Carmo, A. Kaliniczenco, Bárbara Erllen da Silva Alves, Francisco Mendes, Carlos Jesus, Felipe Paiva Fonseca, Flávia de Sousa Gehrke, Carlos Albuquerque, Rita Batista, Madalena Cunha, António Dias, Olivério Ribeiro, Rosa Maria Grangeiro Martins, Teresa Madeira, Catarina Peixoto-Plácido, Nuno Rebelo dos Santos, Osvaldo Santos, Astrid Bergland, Asta Bye, Carla Lopes, Violeta Alarcão, Beatriz Goulão, Nuno Mendonça, Paulo Nicola, J. Gorjão Clara, João Gomes, Ana Querido, Catarina Tomás, Daniel Carvalho, Marina Cordeiro, Marlene Rosa, Alda Marques, Daniela Brandão, Óscar Ribeiro, Lia Araújo, Constança Paúl, Beatriz Minghelli, Sylvina Richaud, Ana Laura Mendes, Joana Marta‐Simões, Inês A. Trindade, Cláudia Ferreira, Teresa Carvalho,
S1 Health literacy and health education in adolescence Catarina Cardoso Tomás S2 The effect of a walking program on the quality of life and well-being of people with schizophrenia Emanuel Oliveira, D. Sousa, M. Uba-Chupel, G. Furtado, C. Rocha, A. Teixeira, P. Ferreira S3 Diagnosis and innovative treatments - the way to a better medical practice Celeste Alves S4 Simulation-based learning and how it is a high contribution Stefan Gisin S5 Formative research about acceptability, utilization and promotion ...
BioMed Central
Produção Nacional
Revisado por pares
Nathália M. Pinheiro, Fernanda Paula Roncon Santana, Rafael Ribeiro Almeida, Marina Guerreiro, Mílton A. Martins, Luciana C. Caperuto, Niels Olsen Saraiva Câmara, Lislaine A. Wensing, Vânia F. Prado, Iolanda de Fátima Lopes Calvo Tibério, Marco A. M. Prado, Carla M. Prado,
Nicotinic α-7 acetylcholine receptor (nAChRα7) is a critical regulator of cholinergic anti-inflammatory actions in several diseases, including acute respiratory distress syndrome(ARDS). Given the potential importance of α7nAChR as a therapeutic target, we evaluated whether PNU-282987, an α7nAChR agonist, is effective in protecting the lung against inflammation. We performed intratracheal instillation of LPS to generate acute lung injury (ALI) in C57BL/6 mice. PNU-282987 treatment, either before or ...
Tópico(s): Receptor Mechanisms and Signaling
2016 - Wiley | The FASEB Journal
Produção Nacional
Revisado por pares
Ana CA Oliveira, Maria CS Pereira, Luana Nazaré da Silva Santana, Rafael M. Fernandes, Francisco Bruno Teixeira, Gedeão Batista de Oliveira, Luanna Melo Pereira Fernandes, Enéas Andrade Fontes-Júnior, Rui Daniel Prediger, Maria Elena Crespo‐López, Walace Gomes‐Leal, Rafael Rodrigues Lima, Cristiane do Socorro Ferraz Maia,
There is increasing evidence that heavy ethanol exposure in early life may produce long-lasting neurobehavioral consequences, since brain structural maturation continues until adolescence. It is well established that females are more susceptible to alcohol-induced neurotoxicity and that ethanol consumption is increasing among women, especially during adolescence. In the present study, we investigated whether chronic ethanol exposure during adolescence through early adulthood in female rats may induce ...
Tópico(s): Fatty Acid Research and Health
2015 - SAGE Publishing | Journal of Psychopharmacology
Produção Nacional
Revisado por pares
Audirene Amorim Santana, Rafael Augustus de Oliveira, Louise Emy Kurozawa, Kil J. Park,
The aim of this study was to evaluate the microencapsulation of pequi pulp by spray drying. A central composite rotational design was used in order to evaluate the effect of the independent variables: inlet air temperature, surfactant concentration and modified starch concentration. The dependent variables were assumed as yield of the process and the product features microencapsulated. A selection of the best process condition was performed to obtain the best condition of a product with the highest ...
Tópico(s): Bee Products Chemical Analysis
2014 - Sociedade Brasileira de Engenharia Agrícola | Engenharia Agrícola
Produção Nacional
Revisado por pares
Audirene Amorim Santana, Rafael Augustus de Oliveira, Aroldo Arévalo Pinedo, Louise Emy Kurozawa, Kil Jin Park,
The objective of this study was to obtain babassu coconut milk powder microencapsulated by spray drying process using gum Arabic as wall material. Coconut milk was extracted by babassu peeling, grinding (with two parts of water), and vacuum filtration. The milk was pasteurized at 85 ºC for 15 minutes and homogenized to break up the fat globules, rendering the milk a uniform consistency. A central composite rotatable design with a range of independent variables was used: inlet air temperature in the ...
Tópico(s): Proteins in Food Systems
2013 - Sociedade Brasileira de Ciência e Tecnologia de Alimentos | Food Science and Technology
María O. López‐Oliva, Virginia Martínez, Águeda Buitrago, Carlos Jiménez, Begoña Rivas, Fernando Escuín, Maria Santana, Rafael Selgas, Teresa Bellón,
Cytomegalovirus (CMV) infection is an ongoing clinical problem in solid-organ transplantation (SOT). Pretransplant CMV serology is currently the only tool for assessing the risk of CMV infection, although cellular immune responses driven by CMV-specific CD4 and CD8 T lymphocytes are important for controlling viral replication. Therefore, the analysis of CMV-specific T cells may be useful for estimating the risk of infection.This is a prospective study of patients with kidney transplants and no prophylactic ...
Tópico(s): Immune Cell Function and Interaction
2013 - Wolters Kluwer | Transplantation
Produção Nacional
Revisado por pares
Patrı́cia Sartorelli, Jeferson Santos Santana, Rafael C. Guadagnin, João Henrique G. Lago, Érika G. Pinto, André G. Tempone, Hélio A. Stefani, Marisi G. Soares, A.A. Silva,
Essential oils of ripe fruits from Schinus terebinthifolius (Anacardiaceae), obtained using a pilot extractor and a Clevenger apparatus were chemically characterized. Due the high amount of (-)- α-pinene in both oils, this monoterpene was tested against the protozoan parasite Trypanosoma cruzi, showing a moderate potential (IC50 63.56 µg/mL) when compared to benznidazole (IC50 43.14 µg/mL). Otherwise, (-)- α-pinene oxide did not showed anti-trypanosomal activity (IC50 > 400 µg/mL) while (-)-pinane showed an IC50 of ...
Tópico(s): Toxin Mechanisms and Immunotoxins
2012 - Brazilian Chemical Society | Química Nova
Produção Nacional
Revisado por pares
Dary Moreira Gonçalves Rigueira, Adam Luís Minho Molinari, Dante Luís Silva Mariano, Rodrigo Reis, Adriana Brizon Portugal, Neildes de Souza Santana, Rafael Alves dos Santos,
Efeitos de borda são modificações nos parâmetros físicos, químicos e biológicos observados na área de contato da margem da floresta com a matriz circundante, sendo a disponibilidade de luz um fator crucial para o seu desencadeamento. O objetivo do estudo foi avaliar a influência da disponibilidade de luz sobre a abundância de espécies pioneiras no interior de fragmentos de uma floresta tropical submontana, no município de Wenceslau Guimarães, Bahia. Os resultados mostram uma redução da abundância ...
Tópico(s): Forest ecology and management
2012 - Sociedade Botânica do Brasil | Acta Botanica Brasilica
Joseph H. Lee, Rong Cheng, Ekaterina Rogaeva, Yan Meng, Yaakov Stern, Vincent Santana, Rafael Lantigua, Martin Medrano, Ivonne Z. Jiménez‐Velázquez, Lindsay A. Farrer, Peter St George‐Hyslop, Richard Mayeux,
A broad region on chromosome 12p13 has been intensely investigated for novel genetic variants associated with Alzheimer disease (AD). We examined this region with 23 microsatellite markers using 124 North European (NE) families and 209 Caribbean Hispanic families with late-onset AD (FAD). Significant evidence for linkage was present in a 5-cM interval near 20 cM in both the NE FAD (LOD = 3.5) and the Caribbean Hispanic FAD (LOD = 2.2) datasets. We further investigated these families and an independent NE ...
Tópico(s): Bioinformatics and Genomic Networks
2008 - Springer Science+Business Media | Neurogenetics
Azucena González‐Coloma, Matı́as Reina, Alberto Medinaveitia, Ana Guadaño, Omar Santana, Rafael A. Martínez‐Díaz, Lastenia Ruiz Mesía, Alenguer Alva, Maritza Grandez, R. ROBLES DIAZ, José A. Gavín, Gabriel de la Fuente,
Tópico(s): Berberine and alkaloids research
2004 - Springer Science+Business Media | Journal of Chemical Ecology