Raffaele De Rosa, Michele Russo, Riccardo Russo, Mario Terzo,
This paper presents a semi-active differential, magneto-rheological fluid limited slip differential, which allows us to bias the torque between the driving wheels. It is based on the magneto-rheological fluid employment, by which it is possible to change, in a controlled manner, the internal friction torque and, consequently, the torque bias ratio. This device is an adaptive one and allows us to obtain an asymmetric torque distribution in order to improve vehicle handling. The device modelling and ...
Tópico(s): Hydraulic and Pneumatic Systems
2009 - Taylor & Francis | Vehicle System Dynamics
Giuseppe Fusai, Dimitri Aristotle Raptis, M.A. Hilal, Claudio Bassi, Marc G. Besselink, Kevin C. Conlon, Brian Davidson, Marco Del Chiaro, Christos Dervenis, Isabella Frigerio, Massimo Falconi, Thilo Hackert, Ewen M. Harrison, Shailesh V. Shrikhande, Ajith K. Siriwardena, Martin Smith, Christopher L. Wolfgang, Aditya Borakati, Deniz Balcı, Muhammed Elhadi, Camila Hidalgo Salinas, Nikolaos Machairas, Giovanni Marchegiani, Atsushi Oba, Christian E. Oberkofler, Ioannis Passas, Reena Ravikumar, Patricia Sánchez‐Velázquez, Martín de Santibañes, Andreas A. Schnitzbauer, Fiammetta Soggiu, Domenico Tamburrino, Pascale Tinguely, Alice C. Wei, Marinos Zachiotis, Kamel Bentabak, Salah Eddine Kacimi, Mehrdad Nikfarjam, Aliaksei Shcherba, Gregory Sergeant, Gustavo Coelho, Orlando Jorge Martins Torres, Nikolay Belev, Ephraim Tang, Christian Diaz, Kongyuan Wei, Maher Hendi, Nikolaos Gouvas, Thalis Christophides, Andrej Nikov, Dalia Fathallah, Mahmoud Saad, Olav Tammik, Heikki Huhta, Laurent Sulpice, Renato Micelli Lupinacci, Zaza Demetrashvili, Gregor A Stavrou, Greece Evangelos Felekouras, Vasileios Papaziogas, Sanjeev Misra, Hashim Talib Hashim, Maytham Al-Juaifari Al-Sader, Sohei Satoi, Khaled Obeidat, Ildar Fakhradiyev, Mohamad Khalife, Muhammed Elhadi, Audrius Dulskas, Shahi Ghani, Alejandro Padilla, Javier Melchor-Ruan, Sarnai Erdene, Amine Benkabbou, Pueya Nashidengo, Jonathan Koea, Nigeria Ademola Adeyeye, Sarah Amro, Walaa Mohammed Alnammourah, Catherine The, Michał Pędziwiatr, Wojciech Polkowski, Sorin Traian Barbu, Daniel Galun, Brian K P Goh, Blaž Trotovšek, Jones Omoshoro-Jones, Benedetto Ielpo, Abdelfatah Abdelmageed, Per Sandström, Alessandra Cristaudi, Beat Gloor, Christoph Kuemmerli, Alaa Hamdan Tishreen, Mohammad Karam Chaaban, Chien Hui Wu, Po-Chih Yang Fu Jen, Oussama Baraket, Mark Taylor, Nigel B. Jamieson, Satheesh Iype, Emmanouil Giorgakis, Motaz Qadan, Sabha Ganai, Hamza Al-Naggar, Onesai Chihaka, A. Behi, Aya Tinhinane Kouicem, Aissam Chibane, C. Bouzid, Kamel Bentabak, I. Bouali, Noureddine Samai, Boudouh Aya, Boutheyna Drid, Anisse Tidjane, Benali Tabeti, Nabil Boudjenan-Serradj, M.H. Larbi, Ilhem Ouahab, Souhem Touabti, Ouahab Ilhem, Souad Bouaoud, Abdoun Meriem, Amel Ouyahia, Aya Tinhinane Kouicem, Meriem Abdoun, M. Raïs, Mounira Rais, Omar Riffi, Salah Eddine Kacimi, Lucas McCormack, Pablo Capitanich, Jeremías Goransky, Martín de Santibañes, Oscar Mazza, Ivana Pedraza Salazar, Darío Ramallo, F de Pablo, Gabriel Gondolesi, Pablo Barros Schelotto, Jorge Centeno, Christos Apostolou, Neil D. Merrett, Adrian Fox, S. Z. Sayed Hassen, Shantanu Joglekar, Sivakumar Gananadha, Rudyard Wake, K. Hagen, Mithra Sritharan, Kat Hall, Vijayaragavan Muralidharan, Kai Brown, Mehrdad Nikfarjam, Daniel Croagh, Mithra Sritharan, Roger Berry, Aly Fayed, Russell Hodgson, Thiep Kuany, Benjamin Loveday, Samuel P. Banting, Alistair Rowcroft, Adrian Fox, Brett Knowles, Lillian Taylor, Lynn Chong, Vin Shen Ban, Marcos V. Perini, Mehrdad Nikfarjam, Yi-Ju Lin, Ali Alsoudani, David Burnett, Kalpesh Shah, Matthew Fuge, Nicholas Bull, Stanley Chen, Suresh Navadgi, Zi Qin Ng, Mikael Johansson, Nur Sabrina Binti Babe Azaman, Andrew Pearson, Christos Apostolou, Hans Jörg Mischinger, Peter Schemmer, Peter Kornprat, Andreas Hauer, Andreas Hauer, Klaus Kirbes, R. Klug, Rudolf Schrittwieser, Alexander Klaus, Alexandra Entschev, Daniel Reichhold, Keti Ugrekhelidze, Marcus Fink, Radoslava Stoyanova, Marah Sabateen, Zainab Mahfoodh, Hamdi Al Shenawi, Rami J. Yaghan, Mohammad Chowdhury, Aliaksei Shcherba, Leonid Kirkovsky, С. В. Коротков, Bert Van Den Bossche, Kim Boterbergh, M. Poortmans, Bart Smet, Sébastien Strypstein, T. Feryn, El Mahdi Wahib, sara oubella, Geert Roeyen, V. Hartman, B. Bracke, Bart Hendrikx, Filip Gryspeerdt, Frederik Berrevoet, Natalie Poortmans, T. Apers, Bart Appeltans, Bart Appeltans, Dennis A. Wicherts, Gregory Sergeant, Fernanda Oliveira Barreto Garcia, Ian Barroso dos Santos, Rafael Pérez García, Rinaldo de Angeli Pinto, Thais Lins Soares Leite, Marciano Anghinoni, Caroline Celestino Girão Nobre, Gustavo Coelho, Ivens Filizola Soares Machado, Nubyhelia Carvalho, Lucio Morais, Aldo Vieira Barros, Gustavo F. Gomes, Igor Lima Buarque, Alessandro Bersch Osvaldt, Matheus Militz, Marcio Boff, Luciano Marcelino, Enilde Guerra, Lucas Torelly, Fábio Luiz Waechter, Pablo Duarte Rodrigues, Uirá Fernandes Teixeira, Alessandro Bersch Osvaldt, Luciano Marcelino, Matheus Militz, E. De B. F. De Mello, Rinaldo Goncalves, Silvio Balzan, Eduardo Jose B Ramos, José Maria Assunção Moraes-Junior, Orlando Jorge Martins Torres, Diego Vaz da Silva, Felipe José Fernández Coimbra, Felipe José Fernández Coimbra, Narimã Marques, Narimã Marques, Sílvio Melo Torres, Adriano Sampaio, Carlos Augusto Canteras, Fábio Ferreira, Marcel Autran C. Machado, Diego R Kleinubing, Livia Lellis, Sarah Luiz Brum, Muhammad Gohar, Boyko Atanasov, Mihail Slavchev, Mihail Slavchev, Nikolay Belev, Panche Krastev, Ivelin Takorov, Nikola Vladov, Radoslav Kostadinov, Tsonka Lukanova, Vassil Mihaylov, Plamen Chernopolsky, Rossen Madjov, Vasil Bozhkov, Vasil Kostov, D. Kostov, Evgeni Nikolaev, Fabrice Muhezagiro, J. M. V. Niyonkuru, Pacifique Irakoze, Elijah Dixon, Elisabeth Lo, Leyo Ruo, D.M. D'Souza, Pablo E. Serrano,
Abstract Background Pancreatic surgery remains associated with high morbidity rates. Although postoperative mortality appears to have improved with specialization, the outcomes reported in the literature reflect the activity of highly specialized centres. The aim of this study was to evaluate the outcomes following pancreatic surgery worldwide. Methods This was an international, prospective, multicentre, cross-sectional snapshot study of consecutive patients undergoing pancreatic operations worldwide ...
Oxford University Press
Andrea Giannini, Violante Di Donato, Francesco Sopracordevole, Andrea Ciavattini, Alessandro Ghelardi, Enrico Vizza, Ottavia D’Oria, Tommaso Simoncini, Francesco Plotti, Jvan Casarin, Tullio Golia D’Augè, Ilaria Cuccu, Maurizio Serati, Ciro Pinelli, Alice Bergamini, Bárbara Gardella, A Dell’Acqua, Ermelinda Monti, Paolo Vercellini, Giovanni D’Ippolito, Lorenzo Aguzzoli, Vincenzo Dario Mandato, Luca Giannella, Cono Scaffa, Antonino Ditto, Francesca Falcone, Chiara Borghi, Mario Malzoni, A. Di Giovanni, Maria Giovanna Salerno, Viola Liberale, Biagio Contino, Cristina Donfrancesco, Michele Desiato, Anna Myriam Perrone, Pierandrea De Iaco, Simone Ferrero, Giuseppe Sarpietro, Maria Grazia Matarazzo, Antonio Cianci, Stefano Cianci, Sara Bosio, Simona Ruisi, L Mosca, Raffaele Tinelli, Rosa De Vincenzo, Gian Franco Zannoni, Gabriella Ferrandina, Marco Petrillo, Giampiero Capobianco, Annunziata Carlea, Fulvio Zullo, Barbara Muschiato, Stefano Palomba, Stefano Greggi, Arsenio Spinillo, Fabio Ghezzi, Nicola Colacurci, Roberto Angioli, Pierluigi Benedetti Panici, Ludovico Muzii, Giovanni Scambia, Francesco Raspagliesi, Giorgio Bogani,
The objective of this work is to assess the 5-year outcomes of patients undergoing conization for high-grade cervical lesions that simultaneously present as risk factors in the persistence of HPV infection and the positivity of surgical resection margins. This is a retrospective study evaluating patients undergoing conization for high-grade cervical lesions. All patients included had both positive surgical margins and experienced HPV persistence at 6 months. Associations were evaluated with Cox ...
Tópico(s): Reproductive tract infections research
2023 - Multidisciplinary Digital Publishing Institute | Vaccines
Giorgio Bogani, Luca Lalli, Francesco Sopracordevole, Andrea Ciavattini, Alessandro Ghelardi, Tommaso Simoncini, Francesco Plotti, Jvan Casarin, Maurizio Serati, Ciro Pinelli, Alice Bergamini, Bárbara Gardella, A Dell’Acqua, Ermelinda Monti, Paolo Vercellini, Innocenza Palaia, Giorgia Perniola, Margherita Fischetti, Giusi Santangelo, Alice Fracassi, Giovanni D’Ippolito, Lorenzo Aguzzoli, Vincenzo Dario Mandato, Luca Giannella, Cono Scaffa, Francesca Falcone, Chiara Borghi, Mario Malzoni, Andrea Giannini, Maria Giovanna Salerno, Viola Liberale, Biagio Contino, Cristina Donfrancesco, Michele Desiato, Anna Myriam Perrone, Giulia Dondi, Pierandrea De Iaco, Simone Ferrero, Giuseppe Sarpietro, Maria Grazia Matarazzo, Antonio Cianci, Stefano Cianci, Sara Bosio, Simona Ruisi, L Mosca, Raffaele Tinelli, Rosa De Vincenzo, Gian Franco Zannoni, Gabriella Ferrandina, Marco Petrillo, Giampiero Capobianco, Salvatore Dessiole, Annunziata Carlea, Fulvio Zullo, Barbara Muschiato, Stefano Palomba, Stefano Greggi, Arsenio Spinillo, Fabio Ghezzi, Nicola Colacurci, Roberto Angioli, Pierluigi Benedetti Panici, Ludovico Muzii, Giovanni Scambia, Francesco Raspagliesi, Violante Di Donato,
Background: Cervical dysplasia persistence/recurrence has a great impact on women's health and quality of life. In this study, we investigated whether a prognostic nomogram may improve risk assessment after primary conization. Methods: This is a retrospective multi-institutional study based on charts of consecutive patients undergoing conization between 1 January 2010 and 31 December 2014. A nomogram assessing the importance of different variables was built. A cohort of patients treated between ...
Tópico(s): Genital Health and Disease
2022 - Multidisciplinary Digital Publishing Institute | Vaccines
Giorgio Bogani, Francesco Raspagliesi, Francesco Sopracordevole, Andrea Ciavattini, Alessandro Ghelardi, Tommaso Simoncini, Marco Petrillo, Francesco Plotti, Salvatore Lopez, Jvan Casarin, Maurizio Serati, Ciro Pinelli, Gaetano Valenti, Alice Bergamini, Barbara Giannella, A Dell’Acqua, Ermelinda Monti, Paolo Vercellini, Giovanni D’Ippolito, Lorenzo Aguzzoli, Vincenzo Dario Mandato, Paola Carunchio, Gabriele Carlifante, Luca Giannella, Cono Scaffa, Francesca Falcone, Stefano Ferla, Chiara Borghi, Antonino Ditto, Mario Malzoni, Andrea Giannini, Maria Giovanna Salerno, Viola Liberale, Biagio Contino, Cristina Donfrancesco, Michele Desiato, Anna Myriam Perrone, Giulia Dondi, Pierandrea De Iaco, Umberto Leone Roberti Maggiore, Mauro Signorelli, Valentina Chiappa, Simone Ferrero, Giuseppe Sarpietro, Maria Grazia Matarazzo, Antonio Cianci, Sara Bocio, Simona Ruisi, Rocco Guerrisi, Claudia Brusadelli, L Mosca, Raffaele Tinelli, Rosa De Vincenzo, Gian Franco Zannoni, Gabriella Ferrandina, Salvatore Dessole, Roberto Angioli, Stefano Greggi, Arsenio Spinillo, Fabio Ghezzi, Nicola Colacurci, Margherita Fischetti, Annunziata Carlea, Fulvio Zullo, Ludovico Muzii, Giovanni Scambia, Pierluigi Benedetti Panici, Violante Di Donato,
Background: Primary prevention through vaccination is a prophylactic approach aiming to reduce the risk of developing human papillomavirus (HPV)-related lesions. No mature and long-term data supported the adoption of vaccination in women undergoing conization. Methods: This is a retrospective multi-institutional study. Charts of consecutive patients undergoing conization between 2010 and 2014 were collected. All patients included had at least 5 years of follow-up. We compared outcomes of patients ...
Tópico(s): Reproductive tract infections research
2020 - Multidisciplinary Digital Publishing Institute | Vaccines
Giorgio Bogani, Violante Di Donato, Francesco Sopracordevole, Andrea Ciavattini, Alessandro Ghelardi, Salvatore Lopez, Tommaso Simoncini, Francesco Plotti, Jvan Casarin, Maurizio Serati, Ciro Pinelli, Gaetano Valenti, Alice Bergamini, Bárbara Gardella, A Dell’Acqua, Ermelinda Monti, Paolo Vercellini, Margherita Fischetti, Giovanni D’Ippolito, Lorenzo Aguzzoli, Vincenzo Dario Mandato, Paola Carunchio, Gabriele Carlinfante, Luca Giannella, Cono Scaffa, Francesca Falcone, Chiara Borghi, Antonino Ditto, Mario Malzoni, Andrea Giannini, Maria Giovanna Salerno, Viola Liberale, Biagio Contino, Cristina Donfrancesco, Michele Desiato, Anna Myriam Perrone, Giulia Dondi, Pierandrea De Iaco, Umberto Leone Roberti Maggiore, Mauro Signorelli, Valentina Chiappa, Simone Ferrero, Giuseppe Sarpietro, Maria Grazia Matarazzo, Antonio Cianci, Sara Bosio, Simona Ruisi, Rocco Guerrisi, Claudia Brusadelli, L Mosca, Raffaele Tinelli, Rosa De Vincenzo, Gian Franco Zannoni, Gabriella Ferrandina, Marco Petrillo, Salvatore Dessole, Roberto Angioli, Stefano Greggi, Arsenio Spinillo, Fabio Ghezzi, Nicola Colacurci, Ludovico Muzii, Pierluigi Benedetti Panici, Giovanni Scambia, Francesco Raspagliesi,
Abstract Objective Conization aims to remove pre-neoplastic lesions of the uterine cervix. Several techniques for conization have been compared, but evidence regarding the most effective therapeutic option is scant. Here, we aimed to compare the recurrence rate following laser conization and loop electrosurgical excision procedure (LEEP) in patients with high-grade cervical dysplasia (HSIL/CIN2+). Methods This is a retrospective multi-institutional study. Medical records of consecutive patients with HSIL/ ...
Tópico(s): Ovarian cancer diagnosis and treatment
2020 - Elsevier BV | Gynecologic Oncology
Paolo Montuori, Ilaria Loperto, Carmine Paolo, Davide Castrianni, Raffaele Nubi, Elvira De Rosa, Raffaele Palladino, Maria Triassi,
Among athletes, bodybuilders are more predisposed to the use of dietary supplements (DS) and hormones (H) to increase in adaptations to physical training and performance. The purpose of the study was to identify social, psychological, and organisational factors that are associated with the use of food supplements and hormones in young bodybuilders of the metropolitan area of Naples.107 athletes, practicing bodybuilding, were consecutively recruited in 30 gyms, randomly selected in the metropolitan ...
Tópico(s): Genetics and Physical Performance
2021 - BioMed Central | BMC Sports Science Medicine and Rehabilitation
Nicola de’Angelis, Gianmaria Casoni Pattacini, D. C. Winter, Filippo Aisoni, Giorgio Bianchi, Paolo Carcoforo, Valerio Celentano, Federico Coccolini, Salomone Di Saverio, Alice Frontali, Christine Denet, David Fuks, Pietro Genova, Mario Guerrieri, Miquel Kraft, Zaher Lakkis, Céphise Antonot, Jeanne Vertier, Bertrand Le Roy, Renato Micelli Lupinacci, Aleix Martínez‐Pérez, Giovanni Domenico De Palma, Marco Milone, Lorenzo A. Orci, Sebastiano Bartoletti, Lauren O’Connell, Monica Ortenzi, Jean-Christophe Paquet, Ornella Perrotto, Roberto Petri, Antonio Santangelo, Stefano Scabini, Raffaele De Rosa, Valeria Tonini, A. Valverde, Enrico Andolfi, Francesca Pecchini, Gianluca Pellino, Alessia Urbani, Laura Vidal, Angelo Restivo, Simona Deidda, Luigi Zorcolo, Frédéric Ris, Eloy Espín, Micaela Piccoli,
Tópico(s): Colorectal Cancer Screening and Detection
2022 - Springer Science+Business Media | International Journal of Colorectal Disease
Raffaele De Rosa, Francesco Di Stazio, Daniele Giordano, Michele Russo, Mario Terzo,
Based on the Fourier heat equation, an analytical model to determine the tyre temperature distribution, during its employment, is described. The model, called ThermoTyre, analyses the tyre thermodynamic behaviour. The model is in one-dimensional form and is characterised by a low computational load. Therefore, it lends to be easily integrated with interaction models in order to execute handling analyses. The work takes advantage of the cooperation with the Bridgestone Technical Center Europe that ...
Tópico(s): Mechanical Engineering and Vibrations Research
2008 - Taylor & Francis | Vehicle System Dynamics
Raffaele De Caterina, Rosa Sicari, W Bernini, Guido Lazzerini, Giuliana Buti Strata, Daniela Giannessi,
Summary Ticlopidine (T) and aspirin (ASA) are two antiplatelet drugs both capable of prolonging bleeding time (BT), with a different mechanism of action. A synergism in BT prolongation has been reported and is currently considered an argument for not recommending their combination. However, a profound suppression of platelet function might be a desirable counterpart of a marked prolongation of BT, with a possible use in selected clinical situations. We therefore studied ex vivo platelet function (aggregation ...
Tópico(s): Atrial Fibrillation Management and Outcomes
1991 - Thieme Medical Publishers (Germany) | Thrombosis and Haemostasis
Jacques Maclouf, Catherine Antoine, Raffaele De Caterina, Rosa Sicari, Ryan C. Murphy, Paola Patrignani, Stefano Loizzo, Carlo Patrono,
We measured the excretion of a major urinary metabolite of leukotriene (LT) C4, i.e., LTE4, during the infusion of exogenous LTC4 to enable estimation of the rate of entry of endogenous LTC4 into the bloodstream. Four healthy volunteers received 2-h intravenous infusions of vehicle alone and LTC4 at 0.063, 0.32, 1.6, and 2.9 pmol.kg-1.min-1 in random order. Urinary LTE4 was measured before, during, and up to 24 h after the infusions. The fractional elimination of LTE4 was independent of the rate ...
Tópico(s): Asthma and respiratory diseases
1992 - American Physical Society | AJP Heart and Circulatory Physiology
Raffaele De Caterina, Rosa Sicari,
Thrombin is a key enzyme in the coagulation cascade being the final effector responsible for the conversion of fibrinogen to fibrin. Thrombin as an enzyme also acts on other substrates of the coagulation system, thus resulting in procoagulant tendencies, potentiation of ongoing reactions, feedback inhibition and/or limitation of clotting. Thrombin also has, however, a number of 'cellular' effects probably not only dependent on its enzymatic activity. This review focuses mostly on present knowledge ...
Tópico(s): Blood Coagulation and Thrombosis Mechanisms
1993 - Elsevier BV | Pharmacological Research
Licia Tomei, Alessandra Vitelli, Raffaele De Francesco, Rosa Vitale, Ilario Incitti, Sergio Serafini, Sergio Altamura,
The RNA-dependent RNA polymerase activity of hepatitis C virus is carried out by the NS5B protein. The full-length protein was previously purified as a non-fusion protein from insect cells infected with a recombinant baculovirus. The characterization is now described of a C-terminal hydrophobic domain deletion mutant of NS5B purified from E. coli. In addition to increased solubility, deletion of this sequence also positively affected the polymerase enzymatic activity. The efficiency of nucleotide ...
Tópico(s): Viral Infectious Diseases and Gene Expression in Insects
2000 - Microbiology Society | Journal of General Virology
Antonella Daniele, Ines Abbate, Catherine Oakley, Porzia Casamassima, Eufemia Savino, A. Casamassima, Giancarlo Sciortino, V De Fazio, Gennaro Gadaleta‐Caldarola, Annamaria Catino, Francesco Giotta, Raffaele De Luca, Rosa Divella,
Matrix metalloproteinases are a family of zinc endopeptidases with proteolytic activity against the extracellular matrix components. In particular, two members of this family named Gelatinase A and B, as amply documented in the literature, play a key role in the process of tumor growth/metastasis in breast and hepatocellular carcinoma. Their activity is regulated by Tissue Inhibitor of metalloproteinases-1 and -2, which are the physiological inhibitor of Gelatinases A and B respectively. The aim ...
Tópico(s): Blood Coagulation and Thrombosis Mechanisms
2016 - Elsevier BV | The International Journal of Biochemistry & Cell Biology
Raffaele De Caterina, Rosa Sicari, Yan An, W Bernini, Daniela Giannessi, Guido Lazzerini, C. Efthymiopoulos, Margherita Strolin‐Benedetti,
Indobufen is an antiplatelet drug able to inhibit thromboxane production and cyclooxygenase-dependent platelet aggregation by a reversible inhibition of cyclooxygenase. Indobufen exists in two enantiomeric forms, of which only d-indobufen is active in vitro in inhibiting cyclooxygenase. In order to verify that also inhibition of platelet function is totally accounted for by d-indobufen, ten patients with proven coronary artery disease (8 male, 2 female, age, mean +/- S.D., 58.7 +/- 7.5 years) were given, ...
Tópico(s): Estrogen and related hormone effects
1992 - Thieme Medical Publishers (Germany) | Thrombosis and Haemostasis
Giovanni Sanesi, Giuseppe Colangelo, Raffaele Lafortezza, Rosa María Calvo de Anta, Clive Davies,
Rapid expansion of urban built-up areas since the 1950s has led to the Milan region becoming one of the major metropolitan areas of Europe. This has been accompanied by significant structural changes to urban and peri-urban landscapes and fragmentation of formerly contiguous green corridors by the distribution of new urban forms such as housing and transport infrastructure. The need to address the loss of green space was first recognised by policy-makers at the end of the 1970s and in due course, ...
Tópico(s): Urban Heat Island Mitigation
2016 - Taylor & Francis | Landscape Research
Piero Fregatti, Marco Gipponi, Gabriele Zoppoli, Matteo Lambertini, Eva Blondeaux, Liliana Belgioia, Raffaele De Rosa, Federica Murelli, Francesca Depaoli, Marcello Ceppi, Alessandro Garlaschi, Daniele Friedman,
Background/Aim: A retrospective study was performed in 246 breast cancer patients to define whether tumor-to-nipple distance (TND) assessment by breast MRI may select patients eligible to nipple-sparing mastectomy (NSM) as compared to permanent section assessment of retroareolar margin. Patients and Methods: Pre- and post-operative parameters including imaging data, histology of the primary tumor, biologic prognostic factors, and adjuvant regimens were retrieved; patients with close/positive retroareolar ...
Tópico(s): Breast Lesions and Carcinomas
2020 - International Institute of Anticancer Research (IIAR) Conferences 1997. Athens, Greece. Abstracts | Anticancer Research
Piero Fregatti, Marco Gipponi, Giulia Atzori, Raffaele De Rosa, Raquel Díaz, Chiara Cornacchia, Marco Sparavigna, Alessandro Garlaschi, Liliana Belgioia, Alessandra Fozza, Francesca Pitto, Luca Boni, Eva Blondeaux, Francesca Depaoli, Federica Murelli, Simonetta Franchelli, Gabriele Zoppoli, Matteo Lambertini, Daniele Friedman,
Clinicopathological features of patients undergoing margin enlargement after lumpectomy for early breast cancer with positive/close excision margins were analyzed in order to define whether a re-operative procedure could have been avoided. Furthermore, a standardized protocol of specimen orientation was adopted in order to optimize both the widening procedure as well as the oncologic outcome.A retrospective analysis was performed including pre-, peri-, and post-operative parameters, and a predictive ...
Tópico(s): Breast Implant and Reconstruction
2022 - Stanford University Highwire Press | In Vivo
Barbara Nicolaus, Agata Gambacorta, Anna Lisa Basso, Raffaele Riccio, Mario De Rosa, William D. Grant,
The non-reducing disaccharide trehalose (α-D-glucopyranosyl-α-D-glucopyranoside) was identified in Sulfolobus solfataricus by 13C NMR spectroscopy. The screening of a range of other archaebacteria, using a rapid isolation and purification procedure for trehalose, indicated that this disaccharide is present in a number of halophilic archaebacteria, thermophilic and sulphur-dependent archaebacteria and methanogenic archaebacteria.
Tópico(s): Geology and Paleoclimatology Research
1988 - Elsevier BV | Systematic and Applied Microbiology
Federico Piscione, Salvatore Cassese, Gennaro Galasso, Plinio Cirillo, Giovanni Esposito, Antonio Rapacciuolo, Dario Leosco, Raffaele Piccolo, Roberta De Rosa, Massimo Chiariello,
Optimal strategy for patients who need coronary revascularization before undeferrable non-cardiac surgery is still unknown. We performed a pilot study of dual antiplatelet therapy discontinuation followed by major non-cardiac surgery and endovascular aortic repair early after successful endothelial-progenitor cell-capture coronary stent deployment.Thirty consecutive patients underwent coronary angioplasty plus stenting, before upcoming endovascular or surgical procedures requiring early interruption ...
Tópico(s): Coronary Interventions and Diagnostics
2009 - Elsevier BV | International Journal of Cardiology
Raffaele Addeo, Carmine De Rosa, Vincenzo Faiola, Luigi Leo, Gregorio Cennamo, Liliana Montella, Rosario Guarrasi, Bruno Vincenzi, Michele Caraglia, Salvatore Del Prete,
Temozolomide (TMZ), an oral methylating imidazotetrazinone, has antitumor activity against gliomas, malignant melanomas, and brain metastasis and is presently administered as a 5-day oral schedule every 4 weeks.A single-institution phase 2 clinical trial was conducted to determine the efficacy and the safety profile of a new regimen based on a dose-intensified, protracted course of TMZ after whole-brain radiotherapy (WBRT). Patients were eligible if they had at least 1 bidimensionally measurable brain ...
Tópico(s): Glioma Diagnosis and Treatment
2008 - Wiley | Cancer
Filomena de Nigris, Licciana Zanella, Francesco Cacciatore, A. Chiara, Flavio Fazioli, Gennaro Chiappetta, Gaetano Apice, Teresa Infante, Mario Monaco, Raffaele Rossiello, Gaetano De Rosa, Marco Alberghini, Claudio Napoli,
Abstract Background The polycomb transcription factor Yin Yang 1 (YY1) overexpression can be causally implicated in experimental tumor growth and metastasization. To date, there is no clinical evidence of YY1 involvement in outcome of patients with osteosarcoma. Prognosis of osteosarcoma is still severe and only few patients survive beyond five years. We performed a prospective immunohistochemistry analysis to correlate YY1 immunostaining with metastatic development and survival in a selected homogeneous ...
Tópico(s): Multiple Myeloma Research and Treatments
2011 - BioMed Central | BMC Cancer
Giustina Ferone, Maria Rosaria Mollo, Helen A. Thomason, Dario Antonini, Huiqing Zhou, Raffaele Ambrosio, Laura De Rosa, Domenico Salvatore, Spiro Getsios, Hans van Bokhoven, Jill Dixon, Caterina Missero,
Ankyloblepharon, ectodermal defects, cleft lip/palate (AEC) syndrome is a rare autosomal dominant disorder caused by mutations in the p63 gene, essential for embryonic development of stratified epithelia. The most severe cutaneous manifestation of this disorder is the long-lasting skin fragility associated with severe skin erosions after birth. Using a knock-in mouse model for AEC syndrome, we found that skin fragility was associated with microscopic blistering between the basal and suprabasal compartments ...
Tópico(s): Hedgehog Signaling Pathway Studies
2012 - Oxford University Press | Human Molecular Genetics
Beatrice De Giulio, Pierangelo Orlando, Gianvincenzo Barba, Raffaele Coppola, Mario De Rosa, Alfonso Sada, P. P. De Prisco, Filomena Nazzaro,
Tópico(s): Gut microbiota and health
2005 - Springer Science+Business Media | World Journal of Microbiology and Biotechnology
Chiara Levante, Fiorenza Ferrari, Chiara Manenti, Faeq Husain‐Syed, Marta Scarpa, Tommaso Hinna Danesi, Massimo de Cal, Valentina Corradi, Grazia Maria Virzì, Alessandra Brendolan, Federico Nalesso, Pércia Bezerra, Salvador López-Giacoman, Sara Samoni, Mara Senzolo, Davide Giavarina, Loris Salvador, Raffaele Bonato, Silvia De Rosa, Enrico Rettore, Claudio Ronco,
Acute Kidney Injury (AKI) is a severe complication affecting many hospitalized patients after cardiac surgery, with negative impacts on short- and long-term clinical outcomes and on healthcare costs. Recently, clinical interest has been aimed at defining and classifying AKI, identifying risk factors and developing diagnostic strategies to identify patients at risk early on. Achieving an early and accurate diagnosis of AKI is a crucial issue, because prevention and timely detection may help to prevent ...
Tópico(s): Chronic Kidney Disease and Diabetes
2017 - SAGE Publishing | The International Journal of Artificial Organs
Giorgio Bogani, Francesco Sopracordevole, Violante Di Donato, Andrea Ciavattini, Alessandro Ghelardi, Salvatore Lopez, Tommaso Simoncini, Francesco Plotti, Jvan Casarin, Maurizio Serati, Ciro Pinelli, Gaetano Valenti, Alice Bergamini, Bárbara Gardella, A Dell’Acqua, Ermelinda Monti, Paolo Vercellini, Margherita Fischetti, Giovanni D’Ippolito, Lorenzo Aguzzoli, Vincenzo Dario Mandato, Paola Carunchio, Gabriele Carlinfante, Luca Giannella, Cono Scaffa, Francesca Falcone, Chiara Borghi, Antonino Ditto, Mario Malzoni, Andrea Giannini, Maria Giovanna Salerno, Viola Liberale, Biagio Contino, Cristina Donfrancesco, Michele Desiato, Anna Myriam Perrone, Giulia Dondi, Pierandrea De Iaco, Valentina Chiappa, Simone Ferrero, Giuseppe Sarpietro, Maria Grazia Matarazzo, Antonio Cianci, Sara Bosio, Simona Ruisi, Rocco Guerrisi, Claudia Brusadelli, L Mosca, Antonio Simone Laganà, Raffaele Tinelli, Mauro Signorelli, Rosa De Vincenzo, Gian Franco Zannoni, Gabriella Ferrandina, Sara Lovati, Marco Petrillo, Salvatore Dessole, Annunziata Carlea, Fulvio Zullo, Roberto Angioli, Stefano Greggi, Arsenio Spinillo, Fabio Ghezzi, Nicola Colacurci, Ludovico Muzii, Pierluigi Benedetti Panici, Giovanni Scambia, Francesco Raspagliesi,
Objective To evaluate the outcomes of high-risk (HR) HPV-positive and -negative women affected by high-grade cervical dysplasia. Methods This is a retrospective multi-institutional study. Medical records of consecutive patients with high-grade cervical dysplasia undergoing conization between 2010 and 2014 were retrieved. All patients included had at least 5 years of follow-up. A propensity-score matching was adopted in order to reduce the presence of confounding factors between groups. Kaplan-Meir ...
Tópico(s): Genital Health and Disease
2021 - Elsevier BV | Gynecologic Oncology
Marika Massaro, Egeria Scoditti, Maria Annunziata Carluccio, Maria Rosa Montinari, Raffaele De Caterina,
Atherosclerosis is a dynamic process with inflammatory aspects playing a considerable pathogenetic role. In this process, the vascular endothelium is the key regulator of vascular function, promoting the maintenance of vascular homeostasis or the progression towards vascular disease. In the past 30 years, the dietary intake of omega–3 (n–3) polyunsaturated fatty acids – mainly derived from fish – has emerged as an important way to modify cardiovascular risk through beneficial effects on all stages of ...
Tópico(s): Eicosanoids and Hypertension Pharmacology
2007 - Karger Publishers | Lifestyle Genomics
Rosa Divella, Raffaele De Luca, Ines Abbate, Emanuele Naglieri, Antonella Daniele,
Adipose tissue in addition to its ability to keep lipids is now recognized as a real organ with both metabolic and endocrine functions.Recent studies demonstrated that in obese animals is established a status of adipocyte hypoxia and in this hypoxic state interaction between adipocytes and stromal vascular cells contribute to tumor development and progression.In several tumors such as breast, colon, liver and prostate, obesity represents a poor predictor of clinical outcomes.Dysfunctional adipose ...
Tópico(s): Cardiovascular Disease and Adiposity
2016 - Ivyspring International Publisher | Journal of Cancer
Paolo Calabró, Plinio Cirillo, Giuseppe Limongelli, Valeria Maddaloni, Lucia Riegler, Rosalinda Palmieri, Giuseppe Pacileo, Salvatore De Rosa, Mario Pacileo, Raffaele De Palma, Paolo Golino, Raffaele Calabrò,
<i>Objective:</i> Atherosclerosis is characterized by endothelial inflammation and dysfunction. Adipose tissue has increasingly been recognized as an active endocrine organ secreting so-called adipokines. Among these, resistin – recently described, but not yet extensively studied – has been defined as a novel inflammatory marker in atherosclerosis. The pathophysiology underlying this interplay, however, remains to be fully characterized. The aim of the study is to determine whether resistin ...
Tópico(s): Cardiovascular Disease and Adiposity
2010 - Karger Publishers | Journal of Vascular Research
Doyle Knight, Olivier Chazot, Joanna M. Austin, Mohammad Ali Badr, Graham V. Candler, Bayram Çelik, Donato De Rosa, Raffaele Donelli, Jeffrey R. Komives, Andrea Lani, Deborah A. Levin, Ioannis Nompelis, Marco Panesi, Giuseppe Pezzella, Bodo Reimann, Özgür Tümüklü, Kemal Yuceil,
The capability for CFD prediction of hypersonic shock wave laminar boundary layer interaction was assessed for a double wedge model at Mach 7.1 in air and nitrogen at 2.1 MJ/kg and 8 MJ/kg. Simulations were performed by seven research organizations encompassing both Navier-Stokes and Direct Simulation Monte Carlo (DSMC) methods as part of the NATO STO AVT Task Group 205 activity. Comparison of the CFD simulations with experimental heat transfer and schlieren visualization suggest the need for accurate ...
Tópico(s): Plasma and Flow Control in Aerodynamics
2017 - Elsevier BV | Progress in Aerospace Sciences