Andrew Robson, George Derbyshire, Alan Beat, Raymond Snoddy Media Editor, David Adams, Kit Malthouse, Deputy Leader, Robert Cole, Andrew Pierce, Greg Hurst and Melissa Kite, James Moore, Adam Sherwin Media Reporter, Frances Gibb Legal Editor, Robert Thicknesse, Anne Woodham, Agence-France Presse, Linda Tsang, Richard Hobson, Sian Flynn, David Blunkett, Philip Howard, Ian Cobain, Carol Midgley, Hilary Finch, Ian De Freitas and Tamara Quinn, Joanna Bale, Nic Hopkins, David Lister Ireland Correspondent, Heather Nicheison, Bronwen Maddox Foreign Editor, Clive Davis, Gabrielle Starkey, Gillian Harris Scotland Correspondent, James Doran Angela Jameson and Ben Webster, James Eve, Jemima Harrison, Joe Joseph, Dr. Thomas Stuttaford, Martin Fletcher, Ben Webster Transport Correspondent, Valerie Elliott Countryside Editor, David McVay, Stewart Tendler Crime Correspondent, Jack Malvern, Dominic Walsh, Steve Bird, Stephen Bovey, Debra Craine, Dalya Alberge Arts Correspondent, Libby Purves, Aamer Anwar, Alan Hamilton, Stephen Farrell, Rodney Milnes, Anatole Kaletsky, Sankrant Sanu, John Yadham, David Hands, Richard Susskind, Nicholas Wapshott, Clive Mathieson Telecoms Correspondent, Caroline Merrell Banking Correspondent, Alex Currie (Registrar and Secretary), Angela Jameson, Vanora Bennett, Daniel McGrory, Edward Fennell, Oliver Kay, Peter Riddell On Politics, Matt Dickinson Football Correspondent, Ann Treneman, Barry Millington, Simon de Bruxelles, John Hopkins Golf Correspondent, Geoffrey Dean, Steuart & Francis, Paul Brookes, Philip Whiteman (Editor), Raymond Keene, Adam Sage, Dr. Jane Collins, Ian Cobain and Damian Whitworth, Edmund Davey, Nigel Cliff, Greg Hurst Parliamentary Correspondent, Caroline Merrell, Oliver Holt, Damian Whitworth, Patrick Nairne, David Pannick QC, Matthew Parris Parliamentary Sketch, David Terry, John Campion, Nick Hasell, David Hands Rugby Correspondent, Nick Szczepanik, John Goodbody, James Doran, Philip Webster Political Editor, N. F. Parker, P. B. Lawson, Anjana Ahuja, Russell Jenkins, Walter Gammie, Anthony Loyd, Mark Court Health Industries Correspondent, Lea Paterson Economics Editor, Clive Mathieson and Chris Ayres, Lan Botham, Diane Fortenberry, Jeremy Hart, Catherine O'Brien, Michael Gove, Janet Fricker, Richard Beeston Diplomatic Editor, David Charter Chief Political Correspondent, Michael Dynes, Graham Searjent, David Sinclair, Catherine Philp, Michael Horsnell, Chris Ayres, James Jackson, Dr Thomas Stuttaford, Stephen Dalton, Richard Morrison, Frances Gibb, Vince Wright, Simon Crompton, Alan Lee Racing Correspondent, Julian Holloway, Sally Patten, Anthony Howard, Edward Gorman Sailing Correspondent, Nigel Hawkes Health Editor and Oliver Wright, Michael Evans Defence Editor and Philip Webster Political Editor, Roly Keating, Patience Wheatcroft, Janine di Giovanni, Christopher Irvine, Richard Lawrence,
... Hilary Finch Orchèstre de Lyon/Robertson Barbican Onegin Ramón Vargas Wigmore Hall The Times A trial of broken ...
2001 - Gale Group | TDA
Rebecca Zarger, John Richard Stepp,
... Silva, Ramón Cuevas-Guzmán, Geilsa Baptista, Miguel Olvera-Vargas, Ramón Mariaca-Méndez Dynamic Edible Plant Theoretical Knowledge in ...
Tópico(s): Ethnobotanical and Medicinal Plants Studies
2004 - University of Chicago Press | Current Anthropology
Thomas W. Bell, J. Ramón Vargas, Gerard A. Crispino,
... hydroboration of functionalized 1-cyclohexylcyclohexenesThomas W. Bell, J. Ramon Vargas, and Gerard A. CrispinoCite this: J. Org. Chem. ...
Tópico(s): Chemical synthesis and alkaloids
1989 - American Chemical Society | The Journal of Organic Chemistry
Robert K. Boeckman, Matthew D. Shair, J. Ramón Vargas, Lesley A. Stolz,
... cyclobutanecarboxaldehydesRobert K. Boeckman Jr., Matthew D. Shair, J. Ramon Vargas, and Lesley A. StolzCite this: J. Org. Chem. ...
Tópico(s): Asymmetric Synthesis and Catalysis
1993 - American Chemical Society | The Journal of Organic Chemistry
J. Costamagna, J. Vargas, Ramón Latorre, A. Alvarado, G. Mena,
Tópico(s): Crystal structures of chemical compounds
1992 - Elsevier BV | Coordination Chemistry Reviews
Fabrice Not, Javier del Campo, Vanessa Balagué, Colomban de Vargas, Ramón Massana,
Over the last decade, culture-independent surveys of marine picoeukaryotic diversity based on 18S ribosomal DNA clone libraries have unveiled numerous sequences of novel high-rank taxa. This newfound diversity has significantly altered our understanding of marine microbial food webs and the evolution of eukaryotes. However, the current picture of marine eukaryotic biodiversity may be significantly skewed by PCR amplification biases, occurrence of rDNA genes in multiple copies within a single cell, ...
Tópico(s): Environmental DNA in Biodiversity Studies
2009 - Public Library of Science | PLoS ONE
Śandalo Rold́an-Vargas, Ramon Barnadas-Rodrı́guez, Manuel Quesada‐Pérez, Joan Estelrich, J. Callejas-Fernández,
In this work, the aggregation of charged liposomes induced by magnesium is investigated. Static and dynamic light scattering, Fourier-transform infrared spectroscopy, and cryotransmission electron microscopy are used as experimental techniques. In particular, multiple intracluster scattering is reduced to a negligible amount using a cross-correlation light scattering scheme. The analysis of the cluster structure, probed by means of static light scattering, reveals an evolution from surface fractals ...
Tópico(s): Surfactants and Colloidal Systems
2009 - American Physical Society | Physical Review E
Pere Ginés, Vicente Arroyo, Vı́ctor Vargas, Ramón Planas, Fernando Casafont, Julián Panés, Melchor Hoyos, L Viladomiu, Antoni Rimola, Rosa M. Morillas, Joan Manuel Salmerón, Àngels Ginès, Rafael Esteban, Joan Rodés,
There is no satisfactory treatment for refractory ascites in patients with cirrhosis. Both peritoneovenous shunts and paracentesis have been used, but there is uncertainty about their relative merits.
Tópico(s): Hepatocellular Carcinoma Treatment and Prognosis
1991 - Massachusetts Medical Society | New England Journal of Medicine
Śandalo Rold́an-Vargas, Ramon Barnadas-Rodrı́guez, Alberto Martín‐Molina, Manuel Quesada‐Pérez, Joan Estelrich, J. Callejas-Fernández,
We study fractal vesicle aggregates whose morphology is conditioned by the interaction between the lipid vesicle membranes and calcium and magnesium ions. These morphologies are probed by means of static light scattering using a cross-correlation scheme that avoids the multiple intracluster scattering. In contrast to the branched structures induced by calcium, we report a singular surface- to mass-fractal transition controlled by the magnesium concentration. From infrared spectroscopy data we conclude ...
Tópico(s): Electrostatics and Colloid Interactions
2008 - American Physical Society | Physical Review E
Ramiro Logares, Stéphane Audic, Sébastien Santini, Massimo C. Pernice, Colomban de Vargas, Ramón Massana,
Abstract Flagellated heterotrophic microeukaryotes have key roles for the functioning of marine ecosystems as they channel large amounts of organic carbon to the upper trophic levels and control the population sizes of bacteria and archaea. Still, we know very little on the diversity patterns of most groups constituting this evolutionary heterogeneous assemblage. Here, we investigate 11 groups of uncultured flagellates known as MArine STramenopiles (MASTs). MASTs are ecologically very important and ...
Tópico(s): Environmental DNA in Biodiversity Studies
2012 - Springer Nature | The ISME Journal
Patrice E. Fort, Francisco Javier Estrada-Mena, Agnès Bordais, Dominique Mornet, José‐Alain Sahel, Serge Picaud, Haydeé Rosas‐Vargas, Ramón Mauricio Coral‐Vázquez, Álvaro Rendón,
The sarcoglycan-sarcospan (SG-SSPN) complex is part of the dystrophin-glycoprotein complex that has been extensively characterized in muscle. To establish the framework for functional studies of sarcoglycans in retina here, we quantified sarcoglycans mRNA levels with real-time reverse transcriptase-polymerase chain reaction (RT-PCR) and performed immunohistochemistry to determine their cellular and subcellular distribution. We showed that the beta-, delta-, gamma-, epsilon-sarcoglycans and sarcospan ...
Tópico(s): Sirtuins and Resveratrol in Medicine
2005 - Elsevier BV | Neuroscience Research
Haydeé Rosas‐Vargas, Ramón Mauricio Coral‐Vázquez, Rosario Tapia, Jose L. Borja, Ricardo A. Salas, F Salamanca,
Penile erection depends on the balanced action between antagonist vasoactive molecules such as nitric oxide (NO) and angiotensin. Endothelial nitric oxide synthase (eNOS) and angiotensin-converting enzyme (ACE) polymorphisms have been associated with endothelial dysfunction, which is described as a cause of erectile dysfunction (ED). Endothelial NOS and ACE are both regulators of vascular and corporal smooth muscle tone, which are connected by interaction between the NO-cyclic guanosine monophosphate ...
Tópico(s): Renin-Angiotensin System Studies
2004 - Wiley | Andrology
Andreas G. Wibmer, Hebert Alberto Vargas, Ramon E. Sosa, Junting Zheng, Chaya S. Moskowitz, Hedvig Hricak,
The purpose of this study was to evaluate the usefulness and diagnostic performance of a 5-point standardized diagnostic certainty lexicon for reporting the likelihood of extracapsular extension (ECE) of prostate cancer on routine staging prostate MRI.This study was a retrospective analysis of routine clinical prostate MRI reports before (254 patients) and after (211 patients) the implementation of a 5-point diagnostic certainty lexicon. Whole-mount step-section pathology of the radical prostatectomy ...
Tópico(s): Radiation Dose and Imaging
2014 - American Roentgen Ray Society | American Journal of Roentgenology
Ramiro Logares, Stéphane Audic, David Bass, Lucie Bittner, Christophe Boutte, Richard Christen, Jean‐Michel Claverie, Johan Decelle, John R. Dolan, Micah Dunthorn, Bente Edvardsen, Angélique Gobet, Wiebe H. C. F. Kooistra, Frédéric Mahé, Fabrice Not, Hiroyuki Ogata, Jan Pawłowski, Massimo C. Pernice, Sarah Romac, Kamran Shalchian‐Tabrizi, Nathalie Simon, Thorsten Stoeck, Sébastien Santini, Raffaele Siano, Patrick Wincker, Adriana Zingone, Thomas A. Richards, Colomban de Vargas, Ramón Massana,
Summary Background Biological communities are normally composed of a few abundant and many rare species. This pattern is particularly prominent in microbial communities, in which most constituent taxa are usually extremely rare. Although abundant and rare subcommunities may present intrinsic characteristics that could be crucial for understanding community dynamics and ecosystem functioning, microbiologists normally do not differentiate between them. Here, we investigate abundant and rare subcommunities ...
Tópico(s): Environmental DNA in Biodiversity Studies
2014 - Elsevier BV | Current Biology
Thomas A. Richards, Guy Leonard, Frédéric Mahé, Javier del Campo, Sarah Romac, Meredith D. M. Jones, Finlay Maguire, Micah Dunthorn, Colomban de Vargas, Ramón Massana, Aurélie Chambouvet,
Environmental DNA and culture-based analyses have suggested that fungi are present in low diversity and in low abundance in many marine environments, especially in the upper water column. Here, we use a dual approach involving high-throughput diversity tag sequencing from both DNA and RNA templates and fluorescent cell counts to evaluate the diversity and relative abundance of fungi across marine samples taken from six European near-shore sites. We removed very rare fungal operational taxonomic ...
Tópico(s): Plant Pathogens and Fungal Diseases
2015 - Royal Society | Proceedings of the Royal Society B Biological Sciences
Yulia Lakhman, Stéphanie Nougaret, Maura Miccò, Chiara Scelzo, Hebert Alberto Vargas, Ramon E. Sosa, Elizabeth J. Sutton, S. Dennis, Hedvig Hricak, Evis Sala,
Pelvic exenteration (PE) is a radical surgical procedure used for the past 6 decades to treat locally advanced malignant diseases confined to the pelvis, particularly persistent or recurrent gynecologic cancers in the irradiated pelvis. The traditional surgical technique known as total PE consists of resection of all pelvic viscera followed by reconstruction. Depending on the tumor extent, the procedure can be tailored to remove only anterior or posterior structures, including the bladder (anterior ...
Tópico(s): Pelvic and Acetabular Injuries
2015 - Radiological Society of North America | Radiographics
José de Jesús Rubio, Panuncio Cruz, L.A. Paramo, Jesús Alberto Meda-Campaña, Dante Mújica‐Vargas, Ramón Silva‐Ortigoza,
The proportional derivative (PD) control is the most employed method in the trajectory tracking of industrial robots. In the PD control, the stability is guaranteed when its gains are very large; however, the tracking error does not decrease to zero when the vibration effects are considered. In this paper, a proportional integral derivative (PID) anti-vibration control is designed for decreasing the vibration effects in the displacements of a robotic manipulator. The semi-global asymptotic stability ...
Tópico(s): Adaptive Control of Nonlinear Systems
2016 - Institute of Electrical and Electronics Engineers | IEEE Latin America Transactions
Nicolás Ernesto Ottone, Claudia Andrea Vargas, Ramón Fuentes, Mariano del Sol,
Walter Thiel developed the method that enables preservation of the body with natural colors in 1992.It consists in the application of an intravascular injection formula, and maintaining the corps submerged for a determinate period of time in the immersion solution in the pool.After immersion, it is possible to maintain the corps in a hermetically sealed container, thus avoiding dehydration outside the pool.The aim of this work was to review the Thiel method, searching all scientific articles describing ...
Tópico(s): Diagnosis and Treatment of Venous Diseases
2016 - Chilean Society of Anatomy | International Journal of Morphology
Caterina R. Giner, Irene Forn, Sarah Romac, Ramiro Logares, Colomban de Vargas, Ramón Massana,
ABSTRACT High-throughput sequencing (HTS) is revolutionizing environmental surveys of microbial diversity in the three domains of life by providing detailed information on which taxa are present in microbial assemblages. However, it is still unclear how the relative abundance of specific taxa gathered by HTS correlates with cell abundances. Here, we quantified the relative cell abundance of 6 picoeukaryotic taxa in 13 planktonic samples from 6 European coastal sites using epifluorescence microscopy ...
Tópico(s): Environmental DNA in Biodiversity Studies
2016 - American Society for Microbiology | Applied and Environmental Microbiology
Jean‐François Mangot, Ramiro Logares, Pablo Sánchez, Francisco Latorre, Yoann Seeleuthner, Samuel Mondy, Michael E. Sieracki, Olivier Jaillon, Patrick Wincker, Colomban de Vargas, Ramón Massana,
Pico-sized eukaryotes play key roles in the functioning of marine ecosystems, but we still have a limited knowledge on their ecology and evolution. The MAST-4 lineage is of particular interest, since it is widespread in surface oceans, presents ecotypic differentiation and has defied culturing efforts so far. Single cell genomics (SCG) are promising tools to retrieve genomic information from these uncultured organisms. However, SCG are based on whole genome amplification, which normally introduces ...
Tópico(s): Genomics and Phylogenetic Studies
2017 - Nature Portfolio | Scientific Reports
Stéphanie Nougaret, Yulia Lakhman, Nicolas Molinari, Diana Feier, Chiara Scelzo, Hebert Alberto Vargas, Ramon E. Sosa, Hedvig Hricak, Robert A. Soslow, Rachel N. Grisham, Evis Sala,
The objective of our study was to investigate whether the CT features of serous borderline tumors (SBTs) differ from those of low-grade serous carcinomas (LGSCs) and to evaluate if mutation status is associated with distinct CT phenotypes.This retrospective study included 59 women, 37 with SBT and 22 with LGSC, who underwent CT before primary surgical resection. Thirty of 59 patients were genetically profiled. Two radiologists (readers 1 and 2) independently and retrospectively reviewed CT examinations ...
Tópico(s): Radiomics and Machine Learning in Medical Imaging
2018 - American Roentgen Ray Society | American Journal of Roentgenology
David López-Escardó, Jordi Paps, Colomban de Vargas, Ramón Massana, Iñaki Ruiz‐Trillo, Javier del Campo,
Although animals are among the best studied organisms, we still lack a full description of their diversity, especially for microscopic taxa. This is partly due to the time-consuming and costly nature of surveying animal diversity through morphological and molecular studies of individual taxa. A powerful alternative is the use of high-throughput environmental sequencing, providing molecular data from all organisms sampled. We here address the unknown diversity of animal phyla in marine environments ...
Tópico(s): Microbial Community Ecology and Physiology
2018 - Nature Portfolio | Scientific Reports
Juan Camilo González Vargas, Ramón Fabregat, Ángela Carrillo-Ramos, Teodor Jové,
Cultural Heritage (CH) refers to the representation of historical places and traditional customs of a specific city or country. Its principal aim is to transmit to future generations how their ancestors lived, and what their customs and buildings were like, etc. Nowadays, there are different technology systems and research investigations that are focused on CH education that use augmented reality (AR), virtual reality (VR), and mixed reality (MR). The aim of this document is to specifically identify ...
Tópico(s): Museums and Cultural Heritage
2020 - Multidisciplinary Digital Publishing Institute | Applied Sciences
Lorena Alarcon-Casas Wright, Rebeca Vargas Ramon, Zona Batacchi, Irl B. Hirsch,
Objective: To present 2 cases in which patients previously diagnosed with type 2 diabetes (T2D) rapidly progressed to insulin dependence following cancer treatment with immune checkpoint inhibitors (ICH). Both patients were subsequently found to be positive for glutamic acid decarboxylase 65 antibodies (+GAD), indicative of type 1.5 diabetes (T1.5D).Methods: Patient history, laboratory results, and treatment course, in addition to review of the relevant literature, are presented.Results: The first case ...
Tópico(s): Neuroendocrine Tumor Research Advances
2016 - Elsevier BV | AACE Clinical Case Reports
Jorge Cime‐Castillo, Rob J.W. Arts, Valeria Vargas, Ramón Moreno‐Torres, Salvador Hernández‐Martínez, Benito Recio-Tótoro, Fabiola Claudio-Piedras, Mihai G. Netea, Humberto Lanz‐Mendoza,
Endoreplication is a cell cycle program in which cells replicate their genomes without undergoing mitosis and cytokinesis. For the normal development of many organisms (from fungi to humans) and the formation of their organs, endoreplication is indispensable. The aim of the present study was to explore whether endoreplication and DNA synthesis are relevant processes during the induction of trained innate immunity in human monocytes and in the Anopheles albimanus mosquito cell line. During the induction ...
Tópico(s): Epigenetics and DNA Methylation
2018 - Frontiers Media | Frontiers in Immunology
Armando Madrazo‐de la Garza, Miguel Dibildox, Antonio Vargas, Juan Ramón Delgado, Jorge Gonzalez, Patricia Yañez,
Objectives To investigate the efficacy and safety of oral pantoprazole, 20 mg (0.5 to 1.0 mg/kg/day) once daily for 28 days, in pediatric patients with reflux esophagitis. Methods Patients in this study (n = 15; 6 to 13 years old, 9 boys) had reflux esophagitis grade Ic or II (Vandenplas classification). The efficacy of pantoprazole to reduce esophageal acid exposure time (pH < 4), reduce the number and duration of reflux episodes, and to increase the percentage of time with gastric pH > 3 was assessed by ...
Tópico(s): Helicobacter pylori-related gastroenterology studies
2003 - Lippincott Williams & Wilkins | Journal of Pediatric Gastroenterology and Nutrition
F. Gilbert McMahon, Jerome R. Ryan, Adesh K. Jain, Ramón Vargas, Svetislav K. Vanov,
Fifty‐five patients with mild to moderately severe essential hypertension were treated with guanabenz (2,6‐dichlorobenzylidene aminoguanidine acetate) in doses from 4 to 16 mg twice daily in a randomized, placebo‐controlled study. The patients treated with placebo in the initial phase of the study were subsequently treated with guanabenz. The mean arterial pressure in the guanabenz group decreased from 130.6 to 107.6; that in the placebo group decreased from 129.6 to 126.6 standing and from 126.6 ...
Tópico(s): Blood Pressure and Hypertension Studies
1977 - Wiley | Clinical Pharmacology & Therapeutics
Adesh K. Jain, Jerome R. Ryan, Ramón Vargas, F. Gilbert McMahon,
In 12 hospitalized patients with hypertension, clonidine 3 times a day led to better control of blood pressure than did the same total dose administered once daily. Compared to the uniform control of blood pressure on divided dose regimen, the single daily 8 P.M. dose led to wider fluctuations and inadequate control 18 hr after dosing. However, 10 of the 12 patients preferred the single daily dose at 8:00 P.M. to the divided dose regimen because of no drowsiness during the day. In 2 patients administration ...
Tópico(s): Pharmaceutical Practices and Patient Outcomes
1977 - Wiley | Clinical Pharmacology & Therapeutics
Ramón Vargas, Miguel Castañeda,
The age-dependent reduction of brain protein synthesis was examined at the initiation step of translation in the rat. Activity of brain initiation factor 2, as well as that of other eukaryotic initiation factors that contribute to the binding of initiator aminoacyl-tRNA to ribosomes, was found to decrease with age and to decline parallel to the decrease in total protein synthesis and brain elongation factor 1 activity. Change in the activity of initiation factors was demonstrated by the results ...
Tópico(s): RNA Interference and Gene Delivery
1983 - Elsevier BV | Mechanisms of Ageing and Development
FG McMahon, Ramón Vargas, Máirín Ryan, Arun K. Jain, RI Abels, Barbara Perry, Smith Il,
Abstract A double-blind, placebo-controlled study of the pharmacokinetics and safety of multiple doses of recombinant human erythropoietin [rHuEPO 150 or 300 U/kg either by intravenous (IV) bolus or subcutaneously (SC)] in normal male subjects demonstrated that rHuEPO had a dose- related effect on the hematocrit independent of the route of administration and that multiple doses of rHuEPO had no direct pressor effects. When rHuEPO was injected IV, a monoexponential decrease in serum EPO level was evident ...
Tópico(s): Dialysis and Renal Disease Management
1990 - Elsevier BV | Blood