Hisao Satô, Yoshiaki Yamaguchi, Kuniaki Makino,
... Cl incorporation into successively zoned amphiboles from the Ramnes cauldron, Norway Hisao Sato; Hisao Sato Shinshu University, ... Cl incorporation into successively zoned amphiboles from the Ramnes cauldron, Norway. American Mineralogist 1997;; 82 (3-4): ... Search Abstract Amphibole from alkali granites in the Ramnes cauldron in the Oslo rift was altered hydrothermally ...
Tópico(s): Geochemistry and Geologic Mapping
1997 - Mineralogical Society of America | American Mineralogist
Tomohiro Shagawa, Hiroomi Torii, Fumihito Kato, Hirotsugu Ogi, Masahiko Hirao,
... resonance acoustic microbalance with a naked embedded quartz (RAMNE-Q) biosensor for evaluating viscoelastic property changes in ... frequency measurement, which is here achieved using the RAMNE-Q biosensor. Simultaneous frequency measurement is performed for ... up to 406 MHz of a 58 MHz RAMNE-Q biosensor during various binding reactions, and evolutions ...
Tópico(s): Adhesion, Friction, and Surface Interactions
2015 - Institute of Physics | Japanese Journal of Applied Physics
Fumihito Kato, Hirotsugu Ogi, Taiji Yanagida, Shintaro Nishikawa, Masahiko Hirao, Masayoshi Nishiyama,
... resonance acoustic microbalance with a naked-embedded quartz (RAMNE-Q) is realized by a microfabrication method, aiming ... broader applications of quartzcrystal microbalance (QCM) biosensors.The RAMNE-Q biosensor consists of three layers; a silicon ...
Tópico(s): Mechanical and Optical Resonators
2012 - Elsevier BV | Biosensors and Bioelectronics
Marina De Filette, Wouter Martens, Kenny Roose, Tom Deroo, Frederik Vervalle, Mostafa Bentahir, Joël Vandekerckhove, Walter Fiers, Xavier Saelens,
... PubMed Scopus (194) Google Scholar, 21De Filette M. Ramne A. Lycke N. Löwenadler B. Saelens X. Fiers ... PubMed Scopus (194) Google Scholar, 21De Filette M. Ramne A. Lycke N. Löwenadler B. Saelens X. Fiers ... using the same mucosal adjuvant (21De Filette M. Ramne A. Lycke N. Löwenadler B. Saelens X. Fiers ...
Tópico(s): RNA and protein synthesis mechanisms
2008 - Elsevier BV | Journal of Biological Chemistry
Tomohiro Shagawa, Hiroomi Torii, Fumihito Kato, Hirotsugu Ogi, Masahiko Hirao,
... resonance acoustic microbalance with a naked-embedded quartz (RAMNE-Q) biosensor. We simultaneously measured the frequency responses ... in specific-binding cases. Thus, the high-frequency RAMNE-Q biosensor can be a powerful tool for ...
Tópico(s): Advanced MEMS and NEMS Technologies
2015 - Institute of Physics | Japanese Journal of Applied Physics
Jürgen Stolz, Martin Vielreicher,
... Navarro S. Llorente B. Rodriguez-Manzaneque M.T. Ramne A. Uber G. Marchesan D. Dujon B. Herrero ... Navarro S. Llorente B. Rodriguez-Manzaneque M.T. Ramne A. Uber G. Marchesan D. Dujon B. Herrero ...
Tópico(s): Bacterial Genetics and Biotechnology
2003 - Elsevier BV | Journal of Biological Chemistry
Alfiya Abekova, Raushan Yerzhebayeva, S.O. Bastaubayeva, K. Konusbekov, T.A. Bazylova, D.I. Babissekova, A.A. Amangeldiyeva,
... 90‟, „RMS-134‟, „RMS-133‟, „RMS-136‟, and „Ramnes‟ were grouped in a cluster that showed the ...
Tópico(s): Wheat and Barley Genetics and Pathology
2022 - | SABRAO Journal of Breeding and Genetics
Anna Stubbendorff, Emily Sonestedt, Stina Ramne, Isabel Drake, Elinor Hallström, Ulrika Ericson,
Current global food systems threaten human health and environmental sustainability. In 2019, the EAT-Lancet Commission on healthy diets from sustainable food systems defined the first global reference diet to improve both areas, but there is no consensus on how to quantify the EAT-Lancet reference diet as a diet index, and its relation to mortality has not been widely studied.
Tópico(s): Diet and metabolism studies
2021 - Elsevier BV | American Journal of Clinical Nutrition

Reynalda Córdova, Nathalie Kliemann, Inge Huybrechts, Fernanda Rauber, Eszter P. Vamos, Renata Bertazzi Levy, Karl‐Heinz Wagner, Vivian Viallon, Corinne Casagrande, Geneviève Nicolas, Christina C. Dahm, Jie Zhang, Jytte Halkjær, Anne Tjønneland, Marie‐Christine Boutron‐Ruault, Francesca Romana Mancini, Nasser Laouali, Verena Katzke, Bernard Srour, Franziska Jannasch, Matthias B. Schulze, Giovanna Masala, Sara Grioni, Salvatore Panico, Yvonne T. van der Schouw, Jeroen W. G. Derksen, Charlotta Rylander, Guri Skeie, Paula Jakszyn, Miguel Rodríguez‐Barranco, José María Huerta, Aurelio Barricarte, Lousie Brunkwall, Stina Ramne, Stina Bodén, Aurora Perez‐Cornago, Alicia K. Heath, Paolo Vineis, Elisabete Weiderpass, Carlos Augusto Monteiro, Marc J. Gunter, Christopher Millett, Heinz Freisling,
There is a worldwide shift towards increased consumption of ultra-processed foods (UPF) with concurrent rising prevalence of obesity. We examined the relationship between the consumption of UPF and weight gain and risk of obesity.
Tópico(s): Obesity, Physical Activity, Diet
2021 - Elsevier BV | Clinical Nutrition
Ana‐Lucia Mayén, Elom K. Aglago, Viktoria Knaze, Reynalda Córdova, Casper G. Schalkwijk, Karl‐Heinz Wagner, Krasimira Aleksandrova, Veronika Fedirko, Pekka Keski‐Rahkonen, Michael F. Leitzmann, Verena Katzke, Bernard Srour, Matthias B. Schulze, Giovanna Masala, Vittorio Krogh, Salvatore Panico, Rosario Tumino, Bas Bueno‐de‐Mesquita, Magritt Brustad, Antonio Agudo, María Dolores Chirlaque López, Pilar Amiano, Bodil Ohlsson, Stina Ramne, Dagfinn Aune, Elisabete Weiderpass, Mazda Jenab, Heinz Freisling,
Abstract Advanced glycation endproducts (AGEs) may contribute to liver carcinogenesis because of their proinflammatory and prooxidative properties. Diet is a major source of AGEs, but there is sparse human evidence on the role of AGEs intake in liver cancer etiology. We examined the association between dietary AGEs and the risk of hepatobiliary cancers in the European Prospective Investigation into Cancer and Nutrition prospective cohort (n = 450 111). Dietary intake of three AGEs, N ε ‐[carboxymethyl] ...
Tópico(s): Fatty Acid Research and Health
2021 - Wiley | International Journal of Cancer
Giles Hanley‐Cook, Inge Huybrechts, Carine Biessy, Roseline Remans, Gina Kennedy, Mélanie Deschasaux, Kris A. Murray, Mathilde Touvier, Guri Skeie, Emmanuelle Kesse‐Guyot, Alemayehu Argaw, Corinne Casagrande, Geneviève Nicolas, Paolo Vineis, Christopher Millett, Elisabete Weiderpass, Pietro Ferrari, Christina C. Dahm, H. Bas Bueno‐de‐Mesquita, Torkjel M. Sandanger, Daniel B. Ibsen, Heinz Freisling, Stina Ramne, Franziska Jannasch, Yvonne T. van der Schouw, Matthias B. Schulze, Konstantinos K. Tsilidis, Anne Tjønneland, Eva Ardanáz, Stina Bodén, Lluís Cirera, Giuliana Gargano, Jytte Halkjær, Paula Jakszyn, Ingegerd Johansson, Verena Katzke, Giovanna Masala, Salvatore Panico, Miguel Rodríguez‐Barranco, Carlotta Sacerdote, Bernard Srour, Rosario Tumino, Elio Ríboli, Marc J. Gunter, Andrew D. Jones, Carl Lachat,
Background Food biodiversity, encompassing the variety of plants, animals, and other organisms consumed as food and drink, has intrinsic potential to underpin diverse, nutritious diets and improve Earth system resilience. Dietary species richness (DSR), which is recommended as a crosscutting measure of food biodiversity, has been positively associated with the micronutrient adequacy of diets in women and young children in low- and middle-income countries (LMICs). However, the relationships between ...
Tópico(s): Child Nutrition and Water Access
2021 - Public Library of Science | PLoS Medicine
Esther González-Padilla, Joana Alves Dias, Stina Ramne, Kjell Olsson, Cecilia Nälsén, Emily Sonestedt,
The evidence on the impact of high sugar consumption on micronutrient dilution does not yet allow for the establishment of clear thresholds of consumption. To establish upper and lower limit intake thresholds for added sugar, more studies from different countries and multiple populations are needed. The aim of this study was to examine the association between the intakes of added sugar and various micronutrients among the adult Swedish population across almost two decades.The data were obtained ...
Tópico(s): Nutrition and Health in Aging
2020 - BioMed Central | Nutrition & Metabolism
Suzanne Janzi, Stina Ramne, Esther González-Padilla, Linda Johnson, Emily Sonestedt,
Aims: Although diet is one of the main modifiable risk factors of cardiovascular disease, few studies have investigated the association between added sugar intake and cardiovascular disease risk. This study aims to investigate the associations between intake of total added sugar, different sugar-sweetened foods and beverages, and the risks of stroke, coronary events, atrial fibrillation and aortic stenosis. Methods: The study population consists of 25,877 individuals from the Malmö Diet and Cancer ...
Tópico(s): Diet and metabolism studies
2020 - Frontiers Media | Frontiers in Nutrition
Stina Ramne, Isabel Drake, Ulrika Ericson, Jan Nilsson, Marju Orho‐Melander, Gunnar Engström, Emily Sonestedt,
It has been suggested that high intake of added sugar and sugar-sweetened beverages (SSBs) increase the level of circulating inflammatory proteins and that chronic inflammation plays a role in type 2 diabetes (T2D) development. We aim to examine how added sugar and SSB intake associate with 136 measured plasma proteins and C-reactive protein (CRP) in the Malmö Diet and Cancer–Cardiovascular Cohort (n = 4382), and examine if the identified added sugar- and SSB-associated proteins associate with T2D incidence. ...
Tópico(s): Diet and metabolism studies
2020 - Multidisciplinary Digital Publishing Institute | Nutrients
Daniel B. Ibsen, Marinka Steur, Fumiaki Imamura, Kim Overvad, Matthias B. Schulze, Benedetta Bendinelli, Marcela Guevara, Antonio Agudo, Pilar Amiano, Dagfinn Aune, Aurelio Barricarte, Ulrika Ericson, Guy Fagherazzi, Paul W. Franks, Heinz Freisling, J. Ramón Quirós, Sara Grioni, Alicia K. Heath, Inge Huybrechts, Verena Katze, Nasser Laouali, Francesca Romana Mancini, Giovanna Masala, Anja Olsen, Keren Papier, Stina Ramne, Olov Rolandsson, Carlotta Sacerdote, María‐José Sánchez, Carmen Santiuste, Vittorio Simeon, Annemieke M. W. Spijkerman, Bernard Srour, Anne Tjønneland, Tammy Y. N. Tong, Rosario Tumino, Yvonne T. van der Schouw, Elisabete Weiderpass, Clemens Wittenbecher, Stephen J. Sharp, Elio Ríboli, Nita G. Forouhi, Nicholas J. Wareham,
OBJECTIVE There is sparse evidence for the association of suitable food substitutions for red and processed meat on the risk of type 2 diabetes. We modeled the association between replacing red and processed meat with other protein sources and the risk of type 2 diabetes and estimated its population impact. RESEARCH DESIGN AND METHODS The European Prospective Investigation into Cancer (EPIC)-InterAct case cohort included 11,741 individuals with type 2 diabetes and a subcohort of 15,450 participants ...
Tópico(s): Consumer Attitudes and Food Labeling
2020 - American Diabetes Association | Diabetes Care
Stina Ramne, Louise Brunkwall, Ulrika Ericson, Nicola Gray, Gunter G. C. Kuhnle, Peter M. Nilsson, Marju Orho‐Melander, Emily Sonestedt,
It has been suggested that a high intake of sugar or sweeteners may result in an unfavorable microbiota composition; however, evidence is lacking. Hence, in this exploratory epidemiological study, we aim to examine if intake of added sugar, sugar-sweetened beverages (SSBs) or artificially sweetened beverages (ASBs) associate with the gut microbiota composition.Participants (18-70 years) in the Malmö Offspring Study have provided blood, urine, and fecal samples and completed both web-based 4 day food ...
Tópico(s): Nutritional Studies and Diet
2020 - Springer Science+Business Media | European Journal of Nutrition
Amy Mullee, Dora Romaguera, Jonathan Pearson‐Stuttard, Vivian Viallon, Magdalena Stępień, Heinz Freisling, Guy Fagherazzi, Francesca Romana Mancini, Marie‐Christine Boutron‐Ruault, Tilman Kühn, Rudolf Kaaks, Heiner Boeing, Krasimira Aleksandrova, Anne Tjønneland, Jytte Halkjær, Kim Overvad, Elisabete Weiderpass, Guri Skeie, Christine L Parr, J. Ramón Quirós, Antonio Agudo, María‐José Sánchez, Pilar Amiano, Lluís Cirera, Eva Ardanáz, Kay‐Tee Khaw, Tammy Y. N. Tong, Julie A. Schmidt, Antonia Trichopoulou, Georgia Martimianaki, Anna Karakatsani, Domenico Palli, Claudia Agnoli, Rosario Tumino, Carlotta Sacerdote, Salvatore Panico, Bas Bueno‐de‐Mesquita, W. M. Monique Verschuren, Jolanda M.A. Boer, Roel Vermeulen, Stina Ramne, Emily Sonestedt, Bethany Van Guelpen, Pernilla Lif Holgersson, Konstantinos K. Tsilidis, Alicia K. Heath, David C. Muller, Elio Ríboli, Marc J. Gunter, Neil Murphy,
Soft drinks are frequently consumed, but whether this consumption is associated with mortality risk is unknown and has been understudied in European populations to date.
Tópico(s): Diet, Metabolism, and Disease
2019 - American Medical Association | JAMA Internal Medicine
Reynalda Córdova, Viktoria Knaze, Vivian Viallon, Petra Rust, Casper G. Schalkwijk, Elisabete Weiderpass, Karl‐Heinz Wagner, Ana‐Lucia Mayén, Elom K. Aglago, Christina C. Dahm, Kim Overvad, Anne Tjønneland, Jytte Halkjær, Francesca Romana Mancini, M-C Boutron-Ruault, Guy Fagherazzi, Verena Katzke, Tilman Kühn, Matthias B. Schulze, Heiner Boeing, Antonia Trichopoulou, Anna Karakatsani, Paschalis Thriskos, Giovanna Masala, Vittorio Krogh, Salvatore Panico, Rosario Tumino, Fulvio Ricceri, Annemieke M. W. Spijkerman, Jolanda M.A. Boer, Guri Skeie, Charlotta Rylander, Kristin Benjaminsen Borch, J.R. Quirós, Antonio Agudo, Daniel Redondo‐Sánchez, Pilar Amiano, J-H. Gómez-Gómez, Aurelio Barricarte, Stina Ramne, Emily Sonestedt, Ingegerd Johansson, Anders Esberg, Tammy Y. N. Tong, Dagfinn Aune, Konstantinos K. Tsilidis, Marc J. Gunter, Mazda Jenab, Heinz Freisling,
Advanced glycation end products (AGEs) can be formed in foods by the reaction of reducing sugars with proteins, and have been shown to induce insulin resistance and obesity in experimental studies. We examined the association between dietary AGEs intake and changes in body weight in adults over an average of 5 years of follow-up. A total of 255,170 participants aged 25–70 years were recruited in ten European countries (1992–2000) in the PANACEA study (Physical Activity, Nutrition, Alcohol, Cessation ...
Tópico(s): Nutritional Studies and Diet
2019 - Springer Science+Business Media | European Journal of Nutrition
Fabian Tillig, Jonas W. Ringsberg, Wengang Mao, Bengt Ramne,
This investigation presents an approach towards a better understanding of achievable accuracy of fuel consumption predictions of ships and provides an example of how a thorough uncertainty analysis of prediction models can be performed. A generic ship energy systems model is used for the fuel consumption prediction of two reference ships: a RoRo ship and a tanker. The study presents how uncertainties can be categorised and handled in four different phases of a ship's life – from early design to ship ...
Tópico(s): Vehicle emissions and performance
2018 - Taylor & Francis | Ships and Offshore Structures
Stina Ramne, Joana Alves Dias, Esther González-Padilla, Kjell Olsson, Bernt Lindahl, Gunnar Engström, Ulrika Ericson, Ingegerd Johansson, Emily Sonestedt,
Although sugar consumption has been associated with several risk factors for cardiometabolic diseases, evidence for harmful long-term effects is lacking. In addition, most studies have focused on sugar-sweetened beverages (SSBs), not sugar per se.The aim of this study was to examine the associations between added and free sugar intake, intake of different sugar sources, and mortality risk.Two prospective population-based cohorts were examined: the Malmö Diet and Cancer Study (MDCS; n = 24,272), which ...
Tópico(s): Diet, Metabolism, and Disease
2018 - Elsevier BV | American Journal of Clinical Nutrition
Sinéad Knight, Helen Plant, Lisa McWilliams, David C. Murray, Rebecca Dixon-Steele, Anet Varghese, Paul Harper, Anna Ramne, Paula McArdle, Susanna Engberg, Neil Bennett, Carolyn Blackett, Mark Wigglesworth,
Cell-based assays have long been important within hit discovery paradigms; however, improving the disease relevance of the assay system can positively affect the translation of small-molecule drug discovery, especially if adopted in the initial hit identification assay. Consequently, there is an increasing need for disease-relevant assay systems capable of running at large scale, including the use of induced pluripotent stem cells and donor-derived primary cells. Major hurdles to adopting these ...
Tópico(s): Pluripotent Stem Cells Research
2017 - Elsevier BV | SLAS DISCOVERY
Fabian Tillig, Jonas W. Ringsberg, Wengang Mao, Bengt Ramne,
There is an environmentally and economically motivated need to reduce the fuel consumption and air emissions of ships. To achieve a reduction in energy consumption, the energy flow in the entire energy system of a ship must be analysed in both the component, or subsystem, level as well as in a holistic way to capture the interactions between the components. Of the currently available energy consumption monitoring and prediction methods or models, no single model or method can be used to assess the ...
Tópico(s): Spacecraft and Cryogenic Technologies
2016 - SAGE Publishing | Proceedings of the Institution of Mechanical Engineers Part M Journal of Engineering for the Maritime Environment
Fumihito Kato, Keisuke Tsurimoto, Hirotsugu Ogi, Masahiko Hirao,
... the resonance acoustic microbalance with naked-embedded quartz (RAMNE-Q) biosensor addition to its original features (label- ...
Tópico(s): Advanced Fiber Optic Sensors
2013 - Institute of Physics | Japanese Journal of Applied Physics
... the resonance acoustic microbalance with naked embedded quartz (RAMNE-Q).(Communicated by Shun-ichi IWASAKI, M.J. ...
Tópico(s): Advanced Biosensing Techniques and Applications
2013 - Japan Academy | Proceedings of the Japan Academy Series B
Gerald Wertheim, Thomas Yang, Tien-Chi Pan, Anna Ramne, Zhandong Liu, Heather Perry Gardner, Katherine D. Dugan, Petra Kristel, Bas Kreike, Marc J. van de Vijver, Robert D. Cardiff, Carol Reynolds, Lewis A. Chodosh,
We previously identified a SNF1/AMPK-related protein kinase, Hunk, from a mammary tumor arising in an MMTV-neu transgenic mouse. The function of this kinase is unknown. Using targeted deletion in mice, we now demonstrate that Hunk is required for the metastasis of c-myc-induced mammary tumors, but is dispensable for normal development. Reconstitution experiments revealed that Hunk is sufficient to restore the metastatic potential of Hunk-deficient tumor cells, as well as defects in migration and ...
Tópico(s): Metabolism, Diabetes, and Cancer
2009 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Dubravka Grdic Eliasson, Karim El Bakkouri, Karin Schön, Anna Ramne, Els Festjens, Björn Löwenadler, Walter Fiers, Xavier Saelens, Nils Lycke,
At present few vaccine candidates exists against potentially pandemic influenza virus infections. We provide compelling evidence that a targeted fusion protein based on the CTA1-DD adjuvant and containing tandem repeats of the matrix protein 2 (M2e) ectodomain epitope, CTA1-3M2e-DD, confers strong protective immunity against a potentially lethal challenge infection with influenza virus in mice. The formulation was highly effective for mucosal immunizations and promoted high M2e-specific serum IgG ...
Tópico(s): Immune Cell Function and Interaction
2008 - Elsevier BV | Vaccine
Monica McNeal, Mitali Basu, Judy A. Bean, John D. Clements, Nils Lycke, Anna Ramne, Björn Löwenadler, Anthony H.-C. Choi, Richard L. Ward,
Intranasal or oral delivery of the chimeric rotavirus VP6 protein MBP::VP6 to mice elicited >90% reductions in fecal rotavirus shedding after murine rotavirus challenge. Protection depended on co-administration of adjuvants, the most effective being bacterial toxins. Because of safety and efficacy concerns following intranasal or oral toxin delivery, protective efficacy of MBP::VP6 after intrarectal delivery with toxin adjuvants was determined and compared to that induced after intranasal and oral ...
Tópico(s): Viral Infections and Immunology Research
2007 - Elsevier BV | Vaccine
Marina De Filette, Walter Fiers, Wouter Martens, Ashley J. Birkett, Anna Ramne, Björn Löwenadler, Nils Lycke, Willy Min Jou, Xavier Saelens,
M2 is the third integral membrane protein of influenza A. M2e, the extracellular, 23 amino acid residues of M2, has been remarkably conserved in all human influenza A strains. This prompted us to evaluate the use of M2e as a potential broad-spectrum immunogen in a mouse model for influenza infection. Genetic fusion of the M2e and hepatitis B virus core (HBc) coding sequences allowed us to obtain highly immunogenic virus-like particles. This M2e–HBc vaccine induced complete protection in mice against ...
Tópico(s): Hepatitis C virus research
2006 - Elsevier BV | Vaccine
Marina De Filette, Anna Ramne, Ashley J. Birkett, Nils Lycke, Björn Löwenadler, Willy Min Jou, Xavier Saelens, Walter Fiers,
Mucosal vaccination requires effective and safe adjuvants. We have evaluated the non-toxic adjuvant CTA1-DD for mucosal vaccination against influenza. CTA1-DD contains the enzymatically active CTA1 subunit of cholera toxin (CT) genetically fused to a gene encoding a dimer of the D-fragment from Staphylococcus aureus protein A. CTA1-DD only binds to Ig-receptor carrying cells of the immune system. Nasal administration of the universal influenza vaccine M2e-HBc in combination with CTA1-DD completely ...
Tópico(s): Receptor Mechanisms and Signaling
2005 - Elsevier BV | Vaccine
Jianghai Zhu, John W. Burgner, Etti Harms, Boris R. Belitsky, Janet L. Smith,
... Navarro S. Llorente B. Rodriguez-Manzaneque M.T. Ramne A. Uber G. Marchesan D. Dujon B. Herrero ...
Tópico(s): Enzyme Production and Characterization
2005 - Elsevier BV | Journal of Biological Chemistry