Ashu Rastogi, Sudhir A. Kulkarni, Sanjay Agarwal, Murtaza Akhtar, Sachin Arsule, Sudhir Bhamre, Deepak Bhosle, Soaham Desai, Manisha Deshmukh, K. V. Giriraja, Jagannath Jagannath, Reema Kashiva, Rajesh Kesavan, Deepak Khandelwal, Sanjay Kolte, Srikanth Kongara, Anil Kumar Darivemula, Ch Raja Bhaskar Venkatasai Madhusudan, Mohammad Asif Haji Pyare Saheb Qureshi, Muthu Ramu, Gunvant Rathod, Sadasiva Rao Yalamanchi, Shobhit Shakya, Prathvi Shetty, Sudagar Singh, Supreet K. Deshpande, Vijay Viswanathan, AG Unnikrishnan,
Importance Preclinical and phase 1/2 studies with esmolol hydrochloride suggest its potential role in treatment of diabetic foot ulcers (DFUs). Objective To study the efficacy of topical esmolol for healing of uninfected DFUs. Design, Setting, and Participants A randomized, double-blind, multicenter, phase 3 clinical trial was conducted from December 26, 2018, to August 19, 2020, at 27 referral centers across India. Participants included adults with DFUs. Interventions Participants were randomized ...
Tópico(s): Pressure Ulcer Prevention and Management
2023 - American Medical Association | JAMA Network Open