Praphasawat Ratsada, Naoki Hijiya, Shinya Hidano, Yoshiyuki Tsukamoto, Chisato Nakada, Tomohisa Uchida, Takashi Kobayashi, Masatsugu Moriyama,
Dual-specificity phosphatase 4 (DUSP4), a MAP kinase phosphatase, has been regarded as a tumor suppressor gene in several cancers. However, high-level expression of DUSP4 is occasionally observed in specific cancers and its functional significance in carcinogenesis is not fully understood. In the present study, we showed that downregulation of DUSP4 suppressed the proliferation of cancer cell lines exhibiting high expression of DUSP4 by inducing apoptosis and cell cycle arrest at G2/M phase. Expression ...
Tópico(s): Cancer-related Molecular Pathways
2020 - Elsevier BV | Biochemical and Biophysical Research Communications
... vehicles were measured on main roads including Yaowarat, Ratsada, Montri, Patipat, Ban Muangmai, Ban Kain, Ban Lipon, ...
Tópico(s): Acoustic Wave Phenomena Research
2019 - | International Journal of Geomate
Anchalee Rawangkan, Pattama Wongsirisin, Grissana Pook-In, Achiraya Siriphap, Atchariya Yosboonruang, Anong Kiddee, Jureeporn Chuerduangphui, Nanthawan Reuk-Ngam, Acharaporn Duangjai, Surasak Saokaew, Ratsada Praphasawat,
Lung cancer, especially non-small cell lung cancer (NSCLC), is one of the most complex diseases, despite the existence of effective treatments such as chemotherapy and immunotherapy. Since cancer stem cells (CSCs) are responsible for chemo- and radio-resistance, metastasis, and cancer recurrence, finding new therapeutic targets for CSCs is critical. Dinactin is a natural secondary metabolite produced by microorganisms. Recently, dinactin has been revealed as a promising antitumor antibiotic via various ...
Tópico(s): Cancer Research and Treatments
2022 - Multidisciplinary Digital Publishing Institute | Antibiotics
Anchalee Rawangkan, Atchariya Yosboonruang, Anong Kiddee, Achiraya Siriphap, Grissana Pook-In, Ratsada Praphasawat, Surasak Saokaew, Acharaporn Duangjai,
Escherichia coli, particularly multidrug-resistant (MDR) strains, is a serious cause of healthcare-associated infections. Development of novel antimicrobial agents or restoration of drug efficiency is required to treat MDR bacteria, and the use of natural products to solve this problem is promising. We investigated the antimicrobial activity of dried green coffee (DGC) beans, coffee pulp (CP), and arabica leaf (AL) crude extracts against 28 isolated MDR E. coli strains and restoration of ampicillin ( ...
Tópico(s): Coffee research and impacts
2023 - Springer Science+Business Media | Journal of Microbiology and Biotechnology
Witchuda Payuhakrit, Pimchanok Panpinyaporn, Wilunplus Khumsri, Gorawit Yusakul, Ratsada Praphasawat, Nitra Nuengchamnong, Sarawoot Palipoch,
Kaab Dum, a prominent indigenous rice variety cultivated in the Pak Phanang Basin of Nakhon Si Thammarat, Thailand, is the focus of our study. We investigate the therapeutic potential of indigenous Kaab Dum rice extract in the context of chronic wounds. Our research encompasses an examination of the nutritional compositions and chemical profiles of Kaab Dum rice extract. Additionally, we assess how the extract affects chronic wounds in TGF-β-induced HaCaT cells. Our evaluation methods include the ...
Tópico(s): Pressure Ulcer Prevention and Management
2024 - Public Library of Science | PLoS ONE
Ratsada Praphasawat, Sarawoot Palipoch, Prasit Suwannalert, Witchuda Payuhakrit, Paween Kunsorn, Sarunya Laovitthayanggoon, Sinittra Thakaew, Narongsuk Munkong, Warangkhana Klajing,
Background. Red rice bran extract (RRBE) contains many biologically active substances exerting antioxidant and anti-inflammatory effects. Aim. To evaluate the anticancer potential of RRBE in human colon cancer cells and its mutagenic/antimutagenic effects on nonmalignant cells. Materials and Methods. The cytotoxic effect of RRBE was determined by trypan blue exclusion in HCT116, HT29 cell lines and a non-cancerous HEK293 cell line, and its antiproliferative effect using MTS and colony formation assay. ...
Tópico(s): GABA and Rice Research
2023 - | Experimental Oncology
Ratsada Praphasawat, Sinittra Thakaew, Anchalee Rawangkan, Rungthip Thongboontho, Pornchai Sooksaen, Sarunya Laovittayangkoon, Warangkhana Klajing, Pongnared Jaengpromma, Paween Kunsorn, Prasit Suwannalert, Witchuda Payuhakrit,
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Tópico(s): Plant Toxicity and Pharmacological Properties
2023 - | World Journal of Oncology
Anong Kiddee, Atchariya Yosboonruang, Achiraya Siriphap, Grissana Pook-In, Chittakun Suwancharoen, Acharaporn Duangjai, Ratsada Praphasawat, Masami Suganuma, Anchalee Rawangkan,
Multidrug-resistant (MDR) bacteria, especially Escherichia coli, are a major contributor to healthcare-associated infections globally, posing significant treatment challenges. This study explores the efficacy of (−)-epigallocatechin gallate (EGCG), a natural constituent of green tea, in combination with ampicillin (AMP) to restore the effectiveness of AMP against 40 isolated MDR E. coli strains. Antimicrobial activity assays were conducted to determine the minimum inhibitory concentrations (MIC) of EGCG ...
Tópico(s): Antibiotic Resistance in Bacteria
2024 - Multidisciplinary Digital Publishing Institute | Antibiotics
Witchuda Payuhakrit, Pimchanok Panpinyaporn, Wilunplus Khumsri, Gorawit Yusakul, Ratsada Praphasawat, Nitra Nuengchamnong, Sarawoot Palipoch,
[This corrects the article DOI: 10.1371/journal.pone.0302662.].
Tópico(s): Wound Healing and Treatments
2024 - Public Library of Science | PLoS ONE
Ratsada Praphasawat, Kanathip Singsai, Phuridee Muenkaew, Sarita Sirisawat, Watanyu Jaewcharoenchai, Sinitra Thakaew, Supatthra Komkhan, Anchalee Rawangkarn,
Gac aril contains high level of carotenoids. This carotenoid possesses several pharmacological properties including antioxidant, anti-inflammatory, and anti-tumor activities.
Tópico(s): Plant tissue culture and regeneration
2024 - West Asia Organization for Cancer Prevention | Asian Pacific Journal of Cancer Prevention