Tina Ravnsborg, Sarah Svaneklink, Lise Lotte Torvin Andersen, Martin R. Larsen, Dorte M. Jensen, Martin Overgaard,
Background Gestational diabetes mellitus (GDM) is a common pregnancy complication associated with adverse outcomes including preeclampsia, caesarean section, macrosomia, neonatal morbidity and future development of type 2 diabetes in both mother and child. Current selective screening strategies rely on clinical risk factors such as age, family history of diabetes, macrosomia or GDM in a previous pregnancy, and they possess a relatively low specificity. Here we hypothesize that novel first trimester ...
Tópico(s): Birth, Development, and Health
2019 - Public Library of Science | PLoS ONE
... N. (1960): Community as Doctor. Tavistock publ. London . Ravnsborg, I. S. (1957): En etterundersökelse av Schizofrene. Nord. ...
Tópico(s): Healthcare Systems and Technology
1963 - Wiley | Acta Psychiatrica Scandinavica
Tina Ravnsborg, Dorthe T. Olsen, Anna Hammerich Thysen, Maja Christiansen, Gunnar Houen, Peter Højrup,
The vitamin D binding protein, Gc globulin, has in recent years received some attention for its role as precursor for the extremely potent macrophage activating factor (GcMAF). An O-linked trisaccharide has been allocated to the threonine residue at position 420 in two of the three most common isoforms of Gc globulin (Gc1s and Gc1f). A substitution for a lysine residue at position 420 in Gc2 prevents this isoform from being glycosylated at that position. It has been suggested that Gc globulin subjected ...
Tópico(s): Diabetes and associated disorders
2010 - Elsevier BV | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
Tina Ravnsborg, Gunnar Houen, Peter Højrup,
The enzyme myeloperoxidase (MPO) is an important part of the neutrophil immune reaction and can be found in alfa granula. The presence of MPO can be used to distinguish acute myelogenous leukemia from acute lymphocytic leukemia. However, the methods employed to do so, such as flow cytometry and immunohistochemistry rely on antibody recognition, and therefore the characterization of the mature MPO, including post-translational modifications, must be considered as important as epitope mapping. MPO ...
Tópico(s): Fungal Infections and Studies
2010 - Elsevier BV | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
... newcomers in the rural Danish marginal municipality of Ravnsborg seeks to reveal processes of bridging/bonding social ...
Tópico(s): Rural development and sustainability
2006 - Springer Science+Business Media | Theory and Society
Tina Ravnsborg, Lise Lotte Torvin Andersen, Natacha Dencker Trabjerg, Lars Melholt Rasmussen, Dorte M. Jensen, Martin Overgaard,
Gestational diabetes mellitus (GDM) is associated with an increased risk of pre-eclampsia, macrosomia and the future development of type 2 diabetes mellitus in both mother and child. Although an early and accurate prediction of GDM is needed to allow intervention and improve perinatal outcome, no single protein biomarker has yet proven useful for this purpose. In the present study, we hypothesised that multimarker panels of serum proteins can improve first-trimester prediction of GDM among obese ...
Tópico(s): Birth, Development, and Health
2016 - Springer Science+Business Media | Diabetologia
Saulius Lukauskas, Andrey Tvardovskiy, Nhuong V. Nguyen, Mara Stadler, Peter Faull, Tina Ravnsborg, Bihter Özdemir Aygenli, Scarlett Dornauer, Helen R. Flynn, Rik G.H. Lindeboom, Teresa K. Barth, Kevin Brockers, Stefanie M. Hauck, Michiel Vermeulen, Ambrosius P. Snijders, Christian L. Müller, Peter A. DiMaggio, Ole N. Jensen, Robert Schneider, Till Bartke,
Abstract DNA and histone modifications combine into characteristic patterns that demarcate functional regions of the genome 1,2 . While many ‘readers’ of individual modifications have been described 3–5 , how chromatin states comprising composite modification signatures, histone variants and internucleosomal linker DNA are interpreted is a major open question. Here we use a multidimensional proteomics strategy to systematically examine the interaction of around 2,000 nuclear proteins with over 80 modified ...
Tópico(s): Protein Degradation and Inhibitors
2024 - Nature Portfolio | Nature
Michael S. Bereman, Edward J. Hsieh, Thomas N. Corso, Colleen K. Van Pelt, Michael J. MacCoss,
... to make a single manual connection (14Kiyonami R. Ravnsborg C. Madsen O. Zabrouskov V. Easy-to-Use, ...
Tópico(s): Analytical Chemistry and Chromatography
2013 - Elsevier BV | Molecular & Cellular Proteomics
Johannes Petrus Maree, Andrey Tvardovskiy, Tina Ravnsborg, Ole N. Jensen, Gloria Rudenko, Hugh‐G. Patterton,
Trypanosomes diverged from the main eukaryotic lineage about 600 million years ago, and display some unusual genomic and epigenetic properties that provide valuable insight into the early processes employed by eukaryotic ancestors to regulate chromatin-mediated functions. We analysed Trypanosoma brucei core histones by high mass accuracy middle-down mass spectrometry to map core histone post-translational modifications (PTMs) and elucidate cis-histone combinatorial PTMs (cPTMs). T. brucei histones ...
Tópico(s): Signaling Pathways in Disease
2022 - Oxford University Press | Nucleic Acids Research
Marcel Welle, Jesper Torbøl Pedersen, Tina Ravnsborg, Maki Hayashi, Sandra Maaß, Dörte Becher, Ole N. Jensen, Christine Stöhr, Michael Palmgren,
Sulfur-containing amino acid residues function in antioxidative responses, which can be induced by the reactive oxygen species generated by excessive copper and hydrogen peroxide. In all Na+/K+, Ca2+, and H+ pumping P-type ATPases, a cysteine residue is present two residues upstream of the essential aspartate residue, which is obligatorily phosphorylated in each catalytic cycle. Despite its conservation, the function of this cysteine residue was hitherto unknown. In this study, we analyzed the function ...
Tópico(s): Trace Elements in Health
2021 - Portland Press | Biochemical Journal
Alf H. Øien, Sigrid Ravnsborg Justad, Olav Tenstad, Helge Wiig,
The presence of collagen and charged macromolecules like glycosaminoglycans (GAGs) in the interstitial space limits the space available for plasma proteins and other macromolecules. This phenomenon, known as interstitial exclusion, is of importance for interstitial fluid volume regulation. Physical/mathematical models are presented for calculating the exclusion of electrically charged and neutral macromolecules that equilibrate in the interstitium under various degrees of hydration. Here, a central ...
Tópico(s): Tissue Engineering and Regenerative Medicine
2013 - Elsevier BV | Biophysical Journal
Morten Zoega, Tina Ravnsborg, Peter Højrup, Gunnar Houen, Christian Schou,
The neutrophil granulocyte is an important first line of defense against intruding pathogens and it contains a range of granules armed with antibacterial peptides and proteins. Proteinase 3 (PR3) is one among several serine proteases of the azurophilic granules in neutrophil granulocytes. Here, we characterize the glycosylation of PR3 and its association with antimicrobial human neutrophil peptides (HNPs, α-defensins) and the effect of these on the mechanism of inhibition of the major plasma inhibitor ...
Tópico(s): Biochemical and Structural Characterization
2011 - Elsevier BV | Journal of Proteomics
Alexandra M. E. Jones, Ruedi Aebersold, Christian H. Ahrens, Rolf Apweiler, Katja Baerenfaller, Mark S. Baker, Emøke Bendixen, Steve Briggs, Philip Brownridge, Erich Brunner, Michael Daube, Eric W. Deutsch, Ueli Grossniklaus, Joshua L. Heazlewood, Michael O. Hengartner, Henning Hermjakob, Marko Jovanović, Craig Lawless, Günter Lochnit, Lennart Martens, Christian Ravnsborg, Sabine Schrimpf, Yhong‐Hee Shim, Deni Šubašić, Andreas Tholey, Klaas J. van Wijk, Christian von Mering, Manuel Weiß, Xue Zheng,
Abstract The community working on model organisms is growing steadily and the number of model organisms for which proteome data are being generated is continuously increasing. To standardize efforts and to make optimal use of proteomics data acquired from model organisms, a new Human Proteome Organisation (HUPO) initiative on model organism proteomes (iMOP) was approved at the HUPO Ninth Annual World Congress in Sydney, 2010. iMOP will seek to stimulate scientific exchange and disseminate HUPO best ...
Tópico(s): Microbial Metabolic Engineering and Bioproduction
2012 - Wiley | PROTEOMICS
... to more outlying municipalities in Denmark. This includes Ravnsborg, a municipality situated in an outlying rural area ...
Tópico(s): Social Capital and Networks
2006 - Djøf Publishing | Dansk Sociologi
Simon Toftholm Jakobsen, Rikke AM Jensen, Maria Stahl Madsen, Tina Ravnsborg, Christian Vaagensø, Majken Siersbæk, Hjörleifur Einarsson, Robin Andersson, Ole N. Jensen, Rasmus Siersbæk,
Tópico(s): Chromatin Remodeling and Cancer
2024 - Nature Portfolio | Nature Genetics
Martin Overgaard, Tina Ravnsborg, Zuzana Lohse, Birgitte Bytoft, Tine D. Clausen, Rikke Beck Jensen, Peter Damm, Kurt Højlund, Claus Højbjerg Gravholt, Sine Knorr, Dorte M. Jensen,
Abstract Aims Adolescent offspring exposed to maternal diabetes during intrauterine life show a less favourable metabolic profile than the background population. Here, we hypothesize that offspring of women with type 1 diabetes (T1D), possess sex‐specific alterations in the serum profile of proteins involved in lipid, metabolic and transport processes and that these alterations are associated with lipid profile and indices of insulin sensitivity and secretion. Methods A prospective nationwide follow‐ ...
Tópico(s): Pancreatic function and diabetes
2021 - Wiley | Diabetic Medicine
Vegard Andersen, Vilde Ravnsborg Gurigard, June Alette Holter, Torben Wisborg,
A rural gradient in trauma mortality disfavoring remote inhabitants is well known. Previous studies have shown higher risk of traumatic deaths in rural areas in Norway, combined with a paradoxically decreased prevalence of non-fatal injuries. We investigated the risk of fatal and severe non-fatal injuries among all adults in Norway during 2002-2016.All traumatic injuries and deaths among persons with a residential address in Norway from 2002-2016 were included. Data were collected from the Norwegian ...
Tópico(s): Climate Change and Health Impacts
2021 - Elsevier BV | Injury
M.T. Nyberg Godiksen, Craig Kinnear, Tina Ravnsborg, Peter Højrup, Sara Granström, Inga Laursen, Paula L. Hedley, Johanna C. Moolman‐Smook, William J. McKenna, J. Koch, Michael Christiansen,
Hypertrophic cardiomyopathy (HCM) is a myocardial disorder, with complications including heart failure, thromboemboli and sudden death. Human and feline HCM (fHCM) are clinically comparable, thus fHCM may serve as a spontaneous animal model. fHCM in Maine Coon (MC) cats is associated with the p.A31P mutation in the cMyBP-C protein. The mutation is located in the cMyBP-C C0-domain which is known to interact with actin. The presence and levels of the wild type and mutated protein in heart tissue from ...
Tópico(s): Cardiovascular Effects of Exercise
2013 - Scientific Research Publishing | Open Journal of Veterinary Medicine
... OF CHLORMETHIAZOLE IN A PRIVATE SANATORIUM I. S. Ravnsborg, I. S. Ravnsborg Modum Bads Nervesanatorium (Head: G. Johnsen, M. D.) ... for more papers by this author I. S. Ravnsborg, I. S. Ravnsborg Modum Bads Nervesanatorium (Head: G. Johnsen, M. D.) ...
Tópico(s): Anesthesia and Sedative Agents
1966 - Wiley | Acta Psychiatrica Scandinavica
SUMMARY The Norwegian Institute of Technology (NTH) has introduced a new type of evaluation. Unlike traditional types of evaluation, this gives students an opportunity to exercise an on-going influence upon their own situation. For each subject that is evaluated, a co–ordinator, the lecturer and some of the students meet regularly to discuss the way the teaching is progressing. If necessary, other lecturers are present at these meetings. At the end of each semester, all the students in the class ...
Tópico(s): Evaluation of Teaching Practices
1990 - Taylor & Francis | European Journal of Engineering Education
Tuuli Kasso, Jens Stenger, Caterina Zaggia, Gianluca Pastorelli, Max Ramsøe, Tina Ravnsborg, Ole N. Jensen, Elsa Yvanez, Chiara Spinazzi-Lucchesi, Matthew J. Collins, Cecilie Brøns,
Abstract Funerary masks played a crucial role in ancient Egyptian burial practices, as part of the rituals to ensure a successful afterlife. This study presents the first comprehensive analysis of a gilded mummy mask from the Roman period in Egypt from the collections of The Ny Carlsberg Glyptotek in Copenhagen. Portraying a young female, the mask belongs to a distinctive group of mummy masks, whose origins can be identified to be coming from the Dakhlah and Kharga oases. The construction of the ...
Tópico(s): Paleopathology and ancient diseases
2024 - Springer Science+Business Media | Heritage Science
Marta T. Ignasiak, Karolina Nowicka-Bauer, Marta Grzechowiak, Tina Ravnsborg, Kamil Frąckowiak, Ole N. Jensen, Mariusz Jaskólski, Bronisław Marciniak,
The mechanisms of one-electron protein oxidation are complicated and still not well-understood. In this work, we investigated the reaction of sensitized photo-oxidation using carboxybenzophenone (CB) as a sensitizer and a PR-10 protein (MtN13) as a quencher, which is intrinsically complicated due to the complex structure of the protein and multiple possibilities of CB attack. To predict and examine the possible reactions precisely, the 3D structure of the MtN13 protein was taken into account. Our ...
Tópico(s): Microbial bioremediation and biosurfactants
2023 - Elsevier BV | Free Radical Biology and Medicine
... 665. 10.1001/archneurpsyc.1946.02300230059006 Google Scholar Ravnsborg, I. S. (1964): Medikamentmisbruk blant alkoholikere. Tidsskr. norske ...
1964 - Wiley | Acta Psychiatrica Scandinavica
... blev der gennemført et forsøg på Fejø i Ravnsborg Kommune. Kultursociologen Peter Duelund var følgeforsker på dette ...
Tópico(s): Education, Healthcare and Sociology Research
1989 - Society of Media Researchers In Denmark | MedieKultur Journal of media and communication research
Ludovica Sofia Guadalupi, Mariachiara Bianco, Tommaso R. I. Cataldi, Tine Ravnsborg, Ole N. Jensen, Cosima Damiana Calvano,
Tópico(s): Protein Hydrolysis and Bioactive Peptides
2025 - Elsevier BV | LWT
Hassan Hijazi, Julie Manessier, Sabine Brugière, Tina Ravnsborg, Marie Courçon, Baptiste Brule, Karine Mérienne, Ole N. Jensen, Anne-Marie Hesse, Christophe Bruley, Delphine Pflieger,
Tópico(s): Machine Learning in Bioinformatics
2025 - American Chemical Society | Journal of Proteome Research
Tópico(s): Communication in Education and Healthcare
1975 - Taylor & Francis | Nordisk Psykiatrisk Tidsskrift
Martin Damsbo, Christian Ravnsborg, Alexandre V. Podtelejnikov, G. Gendeh,
Protein ubiquitination is highly dynamic, reversible and versatile modification that plays a significant role in the myriad of biological functions. For many years it has been known to mediate targeting of proteins for degradation by proteasomes, but recent studies showed that ubiquitination also plays an important role in targeting of proteins for ligand-dependent internalization and other nonproteolytic functions involved in as cell growth, apoptosis, DNA damage repair, immune response and others. ...
Tópico(s): Advanced Proteomics Techniques and Applications
2012 - Association of Biomolecular Resource Facilities | Journal of Biomolecular Techniques JBT
Alexandra M. E. Jones, Ruedi Aebersold, Christian H. Ahrens, Rolf Apweiler, Katja Baerenfaller, Mark S. Baker, Emøke Bendixen, Steve Briggs, Philip Brownridge, Erich Brunner, Michael Daube, Ericw Deutsch, Ueli Grossniklaus, Joshua L. Heazlewood, Michael O. Hengartner, Henning Hermjakob, Marko Jovanović, Craig Lawless, Günter Lochnit, Lennart Martens, Christian Ravnsborg, Sabine Schrimpf, Yhong‐Hee Shim, Deni Šubašić, Klaas Andreastholey, Christian Vanwijk, Manuel Von Mering, Xue Weiss, Christian von Mering, Joshua L. Heazlewood, Dirk Bumann, Gilbert S. Omenn, Sandra Orchard, Juan‐Pablo Albar, Martin Eisenacher, Pierre‐Alain Binz, Salvador Martínez‐Bartolomé, Juan Antoniovizca ¤, Bernd Gro, Miriam Ttrup, Christian Ckmann, K. Stephan, Helmut Grinberg, Park Meyer Andyoung Mok, Ganesh Kumaragrawal, Abhijit Sarkar, Raj Agrawal, Bongani Ndimba, Michael Georgiatanou, Thomas M. Dunn, Rainer Kieselbach, Sixue Cramer, M. M. Chen, Renu Suhail Rafudeen, Bronwynj Deswal, Joshua Barkla, Jenny Heazlewood, Dominique Renaut, Randeep Job,
PROTEOMICSVolume 12, Issue 3 ContentsFree Access Contents – Proteomics 3'2012 First published: 30 January 2012 https://doi.org/10.1002/pmic.201290022AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below ...
Tópico(s): Biotin and Related Studies
2012 - Wiley | PROTEOMICS
Tópico(s): Vietnamese History and Culture Studies
2014 - Naval War College | Naval War College review