Directory of Open Access Books (DOAB)
Book.
1946 - Gale Group | World Scholar Latin America
Cesar Serrano-Garcia, Michael C. Heinrich, Meijun Zhu, Chandrajit P. Raut, Grant Eilers, Gloria Ravegnini, George D. Demetri, Sebastian Bauer, Jonathan A. Fletcher, Suzanne George,
... commonly associated with evolution of secondary kinase mut. REGO is a multi-targeted TKI that inhibits KIT, ... the in vitro and in vivo activity of REGO compared with IM, SU, and sorafenib (SOR) (a multi-TKI structurally related to REGO). Methods: REGO, IM, SU, and SOR inhibition of viability and ... was performed in GISTs responding or progressing on REGO in the academic phase II clinical trial. Results: In GISTs with KIT exon 11 mutant oncoproteins, REGO potently inhibited viability, KIT phosphorylation, and downstream effector ...
Tópico(s): Gastric Cancer Management and Outcomes
2013 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
Andrew Robson, Roy Haycock, David Adams, Andrew Pierce, Chris Ward, Andrew Potter (Chair, Association of British Choral Directors), Kirsty McLeod, Adam Sherwin Media Reporter, Hilary J. French (Head Teacher), Greg Hurst Political Correspondent, Magnus Linklater, Robert Thicknesse, Mark Souster, Ann Tranter, St Abbs, Max Mosley, President, Michael Evans Defence Editor, Cristina Odone, Sam Lister and Philip Webster, Philip Howard, Maurice Woolf, Christine Seib, David Chater, Suna Erdem, ;, James Bone, Rachel Campbell-Johnston, …, Nic Hopkins, Sharon Maxwell Magnus, Tim Reid and James Hider, Richard Irving, Rosalind Renshaw, D. W. S. Gray, Sam Marlowe, James Hider, Kevin Eason, Rosemary Morton Jack, Peter Brown, Valerie Eillott and Laura Peek, Ben Webster Transport Correspondent, Robert Young, Bernard Parke, Dominic Walsh, Steve Bird, Tom Bawden, James Doran Wall Street Correspondent, Gary Jacob, Ken Broad, Joe Morgan, Christopher Bell, Jill Dupleix, Jane Clarke, Richard Ford Home Correspondent, John Hart, Alan Millard, Christine Backley, Phil Gordon, Julian Thomas, Roland Watson, David Hands, Ian MacKinnon, A. W. F. Edwards, Helen Rumbelow, Norman Hammond Archaeology Correspondent, Ian Jarvis, Hugo Rifkind, Angela Jameson, Carl Mortished and Gary Duncan, Russell Kempson, John Geekie, M. S. Ainsworth, Chris Moncrieff (Political editor, Press Association), Oliver Kay, Gerard Baker, Jane Gordon, Lisa Armstrong, Rick Broadbent, Sam Coates, Ann Treneman, Karen Homer, Geoffrey Dean, Rob Wright, Susan Pape, David Powell Athletics Correspondent, Tim Mickleburgh, Raymond Keene, John Russell Taylor, Peter Riddell Political Briefing, Alice Thomas Ellis, Peter Hindley, chief executive, Paul Barter, Felix Schwartz, Ann Dietrich, Chris Campling, Barry J. Lennox, Helen Nugent, Richard Owen, Damian Whitworth, David Terry, David Hands Rugby Correspondent, Siân Morgan, Anna Patty, Jane Pugh, John Farrell, Michele Kirsch, Mel Webb, Neelam Verjee, Joe Bolger and Tom Roundell, Brendan Simms, Angus Clarke, Tom Baidwin, Caitlin Moran, Bronwen Maddox Foreign Editor's, Tegwyn Jones, James Lockwood, Ann Keith, Simon Jenkins, Mark Henderson, Martin Waller, Chris Ayres, Gillian Harris, Zahid Hussain and Catherine Philip, Alan Coren, Laura Peek, John Baldwin, Sarah Butler, Jonathan Clanton, Lydia Hislop, Benedict Nightingale, Stephen Dalton, Tom Roundell, Richard Morrison, Tim Lawson-Cruttenden, Paul Connolly, James Christopher, Charles Tweedie, Adam Sherwin, Vince Wright, Randy Cohen, Alan Lee Racing Correspondent, Helen Rumbelon, J. Michaels, Sam Lister Health Correspondent, Patience Wheatcroft, Nicholas Larence, Joe Bolger, Christopher Irvine, Joy Saunders,
... from a true life class Visual Art Paula Rego's work tells some compelling stories, says Rachel Campbell-Johnston Paula Rego Tate Britain She explores the buried domain of ...
2004 - Gale Group | TDA
Mohamad Bassam Sonbol, Raed Benkhadra, Zhen Wang, Belal Firwana, Daniel Walden, Kabir Mody, Joleen M. Hubbard, M. Hassan Murad, Daniel H. Ahn, Tanios Bekaii‐Saab,
... 445 patients) were included. Direct comparisons showed that Rego 160 and TAS-102 as monotherapy were superior ... best-supportive care (BSC) in terms of PFS (Rego 160: hazard ratio [HR], 0.4; 95% confidence ... 46 CI, 0.40-0.52) and OS (Rego 160: HR, 0.67; CI, 0.48-0. ... no statistically difference in PFS or OS between Rego 160 and TAS-102. Rego 80+ was superior to BSC in terms of ... HR, 0.37; CI, 0.21-0.66). Rego 80+ was associated with statistically nonsignificant improvement in OS and PFS compared with TAS-102 and Rego 160.Regorafenib 160 and TAS-102 appear to ...
Tópico(s): Hepatocellular Carcinoma Treatment and Prognosis
2019 - AlphaMed Press | The Oncologist
James Landale, Giles Tremlett, Jon Ashworth, Lynne Greenwood, Karen Woolfson and Anne Ashworth, Mike Gerrard, Professor S. R. Sonyel, Mike Crow, Stella Shamoon, Joanna Hunter, Robert Cole, Julian Muscat, Tennis Correspondent, Patricia Davies, Adrian Lee, David Jackson, Rob Hughes, Sarah Potter, Sarah Anticoni, Lottle Moggach, Jane MacQuitty, Simon Barnes, Tom Robbins Personal Assistant, Simon De Bruxelles and Victoria Fletcher, John Morgan, Christopher Borthen, Editor, Lucinda Lambton, Paul Hoggart, Mark Souster, Richard Hobson, Ivo Tennant, Jason Barbour, Gavin Lumsden, Martin Heenderson, Philip Howard, Jeremy Kingston, Joanna Bale, James Bone, Rachel Campbell-Johnston, Clive Davis, Alexandra Frean Social Affairs Correspondent, K. W., Lynne Truss, Peter Foster, Anne Robinson, Simon Wilde, Horacio Rosa, Tony Patrick, Kevin Eason, Geoff Brown, Nilgin Yusuf, Clare Stewart, W. Johnson, Louise Godfrey, John Thicknesse, Madeleine Kingsley, Pat Gibson, John Clarke, Robert Sheehan, David Lancaster, D. R., Stewart Tendler Crime Correspondent, L. Novik, Janet Bush, Economics Editor, amandip uppal, Jean-Christophe Novelli, Dominic Walsh, Ruth Gledhill, Debra Craine, Patrick Humphries, John O'leary, Education Editor, Matthew Barbour, Alan Road, Carol Midgley, Media Correspondent, Tom Walker and Michael Evans Defence Correspondent, Stephen Anderton's, Ruth Gledhill Religion Correspondent, Jason Niss?, Stanley Jacobs, Candida Crewe, Roger Cookson, Robin Young, Alan Hamilton, Peter Millar, Jenny MacArthur, Michael Clark, T. P., Doug Sager, Ertan Hurer, Frances Bissell, Ben MacLntyre, P. B., Martin Fletcher Chief Ireland Correspondent, Janet Bush and Robert Whymant, Martin Symington, Tony Dilley, Caroline Merrell and Susan Emmett, Jonathan Sacks, Peter Barnard, Michael Binyon Diplomatic Editor, Derwent May, Jean Wood, Jasper Gerard, Ben Reed, Valerie Elliott Whitehall Editor, Russell Kempson, Lizanne Rose, Nicholas Watt Political Correspondent, Anthony Lewis, Daniel McGrory, Cath Urquhart Traveller Editor, Stephen Anderton, Paul Durman, Lisa Grainger, Helen Wallace, Andrew Pierce and Michael Gove, John Paul, John Hopkins, Judith Wilson, Gabriella Gamini, L. G., Christina Koning, Adam Jones, Simon Veness, Raymond Keene, Andrew Bamji, Director, Robert Menzies, David Robinson, Alan franks, Alan Lee, Cricket Correspondent, John Russell Taylor, Matt Dickinson, P. W., Lucy Pinney, Alix Ramsay, James Allcock, Elaine Showalter, Richard Evans, Caroline Merrell, Robin Neillands, Bronwen Maddox, Michael Arditti, Oliver Holt, Richard Owen, Damian Whitworth, John Givens, graham wood, Erica Wagner, John Stern, Oliver August, John diamond, Philip Webster, Political Editor, Robert Cole, City Correspondent, Stephanie Billen, Oliver Holt, Football Correspondent, Dalya Alberge, Nicholas Wood, Anne Ashworth, Dominic Kennedy, Giles Whittell, L. G, Jasper Gererd, Simon De Bruxelles, Jane Shilling, Michael Gove and Andrew Pierce, Alex O'Connell, B. N. Warrener, Jason Nissé, Mel Webb, Craig Lord, Georgina Wroe, Kevin McCarra, Andrew Yates, Chris McGrath, Tim Wapshott, Michael Hornsby, Russell Jenkins, Sheila Keating, Alan Lee, Simon Brooke, Jane Owen, Ben MacIntyre, Helen Pridham, Frane, Brian Glanville, Jeffrey Robinson, Philip Webster, Mike Cable, David Bowker, Michael Mabbs, C. M. White, Simon Jenkins, Fraser Nelson, Richard Miles, Anne Ashworth Personal Finance Editor, Mark Henderson, Trevor Fishlock, Lisa Verrico, Gillian Harris, Danny Baker, Lottie Moggach, Geoffrey E. Barlow, Michael Rich, Benedict Nightingale, Tom Rhodes, Marianne Curphey, Joan Rankin, Tony Gilland Director, Jill Crawshaw, David Powell, Jack Bailey, Sam Kiley, Michael Henderson, Ben MacIntyre Nigel Hawkes, Charlie Porter, Annie Flury, Conal Gregory, Jill Todd, Douglas Kennedy, Gina Kent, David Hands, Rugby Correspondent, Gill Hornby, Edward Marriott, Linda O'Callaghan, Christopher Irvine, Nigel Nicolson, Terri Paddock, Susan Emmett, Arthur Dicken Manager,
... an objet d'art in Kent view Paula Rego's best work at half-price in Dulwich ... Place Opera Dr Ox's Experiment Offer! Paula Rego Art and Craft South East Open Studios 98 ...
1998 - Gale Group | TDA
... potential anticancer drugs. Dual drug delivery of Regorafenib (REGO) and Cisplatin (PT) exhibits a great anticancer potential, as REGO enhances the effect of PT treatment of human ... providing stability of the microenvironment. However, encapsulation of REGO and PT fanatical by methoxypoly(ethylene glycol)-block- ... incompetent owing to unsuitability between the binary Free REGO and PT core and the polymeric system. Now, ... can be co-encapsulated in PLGA NPs alongside REGO to stimulate excellent anticancer property. The occurrence of ...
Tópico(s): Dendrimers and Hyperbranched Polymers
2020 - Taylor & Francis | Drug Delivery
Karen Attar, Elizabeth Durack, Lea Paterson and Clive Mathieson, Victoria McKee, Quentin Matthews, Jon Ashworth, Sally Staples, Cath Urquhart, Robert Cole, Andrew Pierce, Giles Whittell and Roger Boyes, James Moore, Patricia Davies, jill Crawshaw, Grace Bradberry, Johnny Dee, Sarah Potter, Jilly Shaul, Jane MacQuitty, Simon Barnes, Gary Neville, Simon Rocker, John Morgan, Andrew Morgan, Paul Hoggart, Muriel Goodings, Emma Haughton, Ivo Tennant, Robert Lea, Douglas Friedli, E. S. MacKenzie, Philip Howard, Adam Mars-Jones, James Bone, K. M. G. Pollard, Elizabeth Judge, Phil Cosgrove, Carl Mortished, Sharon Linnard, Dominic Bradbury, Jeremy Whittle, Tony Patrick, Kevin Eason, Clare Stewart, Richard Dobson, Andrew Norfolk, John O'Leary Education Editor, Mark R. Harrisson, Antonia Senior, Pat Gibson, Valerie Elliott Countryside Editor, Joseph Torra, Paul McCann Media Correspondent and Andrew Norfolk, D. R., Steve Keenan, Thrasy Petropoulos, Jason Allardyce, Melanie Tringham, David Charter Education Correspondent, Ivor Davies, Dominic Walsh, Jerome Boyd Maunsell, Shirley English, R. M., Alix Ramsay Tennis Correspondent, Anthony Wethered, Grainne Gilmore, Michael Harvey, Dalya Alberge Arts Correspondent, Richard Ford Home Correspondent, Candida Crewe, Alan Hamilton, Oliver Wright, Stephen Farrell, Mark Inglefield, Mike Rosewell Rowing Correspondent, simon kinnersley, T. P., Alice Lagnado, Valerie Elliott Countryside Editor and Roland Watson, Nick Wyke, Jayne Dowle, Helen Rumbelow Medical Reporter, Tim Lott, Roland Watson, Frances Bissell, P. B., Catherine Lockwood, Adrienne May, Peter Barnard, Matt Dickinson and Michael Harvey, Tim Teeman, Nick Conway, Derwent May, Stewart Tendler and Roland Watson, Lisa Jardine, Malcolm Smith, Gabriel Roth, Russell Kempson, Paula Hawkins, Robert Cole City Correspondent, R. K. Dart, Ed Potton, Paul Armstrong, David Charter and Paul Wilkinson, Christopher Martin-Jenkins Chief Cricket Correspondent and Inigo Gilmore, David Lilley, M. M., Matt Dickinson Football Correspondent, Jenny Booth, Christopher Martin-Jenkins, Simon de Bruxelles, Geoffrey Dean, Rob Wright, Noel Smith, Stephen Wood, Meredith Etherington-Smith, Adam Jones, Paul Peachey, Rachael Jolley, Stuart Nicholson, Raymond Keene, Adam Sage, David Robinson, Clive Mathieson, Matthew Pryor, Simon Wilkinson, Lucy Pinney, James Allcock, David Thewlis, Martin Jackson, Jeannette Hyde, Min Cooper, Martin Biggs (President), Christopher Walker Chief Ireland Correspondent, Chris Ayres Media Business Correspondent, Cathy Harris, Elizabeth Jackaman, Mathhew Parris, Shane Warne, Damian Whitworth, Christopher Martin-Jenkins Chief Cricket Correspondent, Marcel Berlins, Roger Boyes, John Stern, richard cork, Nick Hasell, Chloë Bryan-Brown, Tom Baldwin and Philip Webster, Michael Leschziner (Professor), David Hands Rugby Correspondent, Jennifer O'Neill, Adam Fresco, Martin Fletcher European Correspondent, david dowaton, Simon Munk, James Doran, David Lynd, Nicholas Browne, Jane Shilling, Jonathon Porritt, Mel Webb, William Oddie, Peter Rolfe, Richard Miles Deputy Personal Finance Editor, Elizabeth Rowlands, Alan Sanders, Tim Wapshott, Russell Jenkins, Michael Austin, Alan Lee, Jane Owen, Stewart Tendler and Christopher Walker, Ben MacIntyre, Helen Pridham, Stephen J. Wozniak, Michael Dynes, Graham Searjeant, Richard Miles, Adam Sherwin and Michael Harvey, Ian Strange, Martin Waller, sudi pigott, Chris Ayres, Nigel Hawkes Science Editor, Fran Littlewood, Mark Baldwin, Cox's Casebook, Allan Bula, Nora Seton, Benedict Nightingale, Stamp, Jack Bailey, Alyson Rudd, Tom Chesshyre, Paul Connolly, Valerie Grove, Gordon Brown, Roland Watson, Roger Boyes, Adam Sage and Richard Owen, Alan Lee Racing Correspondent, Susie Steiner, Sally Patten, Oliver Bennett, Jan Raath, P. W. Crane, Christopher Irvine, Susan Emmett,
... Picture Gallery No Title Schreiber Picture Gallery Paula Rego's triptych Betrothal: Lessons: Wreck… Sky asserting their ... Nash's placid… Even more satirical is Paula Rego's three-part… Sky asserting their power near ...
2000 - Gale Group | TDA
Beini Sun, Hongce Chen, Xiaoping Wang, Tongsheng Chen,
Abstract Regorafenib (REGO) is a synthetic oral multi-kinase inhibitor with potent antitumor activity. In this study, we investigate the molecular mechanisms by which REGO induces apoptosis. REGO induced cytotoxicity, inhibited the proliferation and migration ability ... oxygen species (ROS)-dependent apoptosis in cancer cells. REGO downregulated PI3K and p-AKT level, and prevented ... Most importantly, AKT agonist (SC79) not only inhibited REGO-induced FOXO3a nuclear localization and apoptosis but also ... migration ability of cancer cells, further demonstrating that REGO prevented FOXO3a nuclear export by deactivating PI3K/AKT. ...
Tópico(s): Cell death mechanisms and regulation
2023 - Springer Nature | Cell Death Discovery
Peter Tandy, Andrew Robson, Eve Peasnall, Julia Llewellyn Smith, C. L. Kauffmann, Peter Brookes, Jon Ashworth, Cath Urquhart, Ted Dodson, Raymond Snoddy Media Editor, Matthew Bannister, R. C. Lane, Stella Shamoon, David Charter Health Correspondent, Robert Cole, Catherine Riley, Andrew Pierce, Flona Beckett, James Moore, Sarah Potter, Maggie Alderson, Barbara Segall, Jane MacQuitty, Frances Gibb and Richard Ford, Salome Munuo, Paul Hoggart, jonathan meades, Mark Souster, Tom Gard, Richard Hobson, Martin Richards, Ivo Tennant, Spiro James, Philip Howard, William Waldegrave, Jeremy Kingston, James Bone, Ian Watson, Eve Dunne, Gabrielle Starkey, E. Jane Dickson, Kevin Eason, Raymond Snoddy, Clare Stewart, Jonathan Lennis, David Chater, Andrew Norfolk, John Thicknesse, Antonia Senior, Martin Fletcher, Pat Gibson, Valerie Elliott Countryside Editor, David McVay, Ralph Harris, Steve Keenan, Thrasy Petropoulos, Stewart Tendler Crime Correspondent, Paula Hawkins and Antonia Senior, Steve Bird, Debra Craine, James Landale Tom Baldwin and Greg Hurst, Alix Ramsay Tennis Correspondent, Jill Dupleix, Jonathan Gornall, Bob Constanduros, Angela LeROY, Alan Hamilton, Robin Young, Nicholas Roe, Rodney Milnes, David Colvin, Andy Stephens, Peter Millar, Jenny MacArthur, simon kinnersley, James Landale Political Correspondent and Edward Gorman, Emma Lindsay, David Hands, Charles Bremner, Malcolm Ross-Thomas, Fanny Blake, Helen Rumbelow, Paula Rego, Anthea Lawson, Tim Teeman, Adrian Cross, Clive Mathieson Telecoms Correspondent, Caroline Merrell Banking Correspondent, Patience Wheatcroft Business Editor, Derwent May, Angela Jameson, Edward Gorman, Ivan Hewett, Will Greenwood, David Lister and Roland Watson, Emma Mahony, Judith Howard, Mitchell B. Bowman, Nigel Williamson, Daniel McGrory, Ed Potton, Oliver Kay, Walter J. Ablett, Stephen Anderton, Peter Childs, Stevie Chick, David Lister, Mark Atherton, Robin Russell-Jones, Rick Broadbent, Jill Sherman Whitehall Editor, Simon de Bruxelles, John Hopkins Golf Correspondent, Geoffrey Dean, Rob Wright, Roland Watson and David Lister, Stephen Farrell and Zahid Hussain, Helen Vaughan-Jones, David Powell Athletics Correspondent, Tim Scott, Raymond Keene, Vaughan Freeman, Lewis Smith, Matthew Pryor, Clive Mathieson, Lucy Pinney, Philip Stott, Paul Wilkinson, James Allcock, John Phillips and Richard Beeston, Min Cooper, Caroline Merrell, Ben Webster Transport Correspondent and Mia Jarlov, Oliver Holt, Helen Nugent, Damian Whitworth, Christopher Martin-Jenkins Chief Cricket Correspondent, Mick Hume, David Blundell, Roger Boyes, Marcel Berlins, Nick Hasell, Sean Thomas, David Hands Rugby Correspondent, James Collard, Adam Fresco, Andrew Norfolk and Glen Owen, Anne Ashworth, John Goodbody, Dearbáil Jordan, Mary Ann Sieghart, Wyndham Thomas, Alan Copps, Katty Kay, Sian Morgan, Jane Shilling, Deanne Holmes, Linus Gregoriadis, William Oddie, Guy Mansell, Kevin McCarra, Matthew Parris, Jennai Cox, joanna coles, Mike Rosewell, Chris McGrath, Marjorie Yue, Tim Wapshott, Russell Jenkins, Glen Owen Education Correspondent, Michael Austin, Alan Lee, Walter Gammie, BeRo, Ben MacIntyre, Lea Paterson Economics Editor, Jeremy Hart, John Goodbody Sports News Correspondent, Dan Naremore, Richard Beeston Diplomatic Editor, Gary Watkins, Ian Whittell, Richard Miles, John Naish, Simon Jenkins, Anthony Mellows, Martin Waller, Chris Ayres, Peter Ingham, Danny Baker, Fran Littlewood, Mark Baldwin, Nigel Hawkes Health Editor, Richael Jolley, James Jackson, Henry Haslam, John Slome, Stephen Dalton, Jill Crawshaw, Stephen Gardiner, G. Stricker, Peter Smith, W. H. Auden, Richard Morrison, Roland Watson and David Lister and Tom Baldwin, Bill Edgar, Lionel Blumenthal, Tom Chesshyre, Arthur Leathley, Fred Dellar, Benedict Birnberg, Sally Patten, Nick Baty, Edward Gorman Sailing Correspondent, John Barclay, Jonathan Gill, Sally Patten Retail Correspondent, Gill Hornby, Patience Wheatcroft, Christopher Irvine, Susan Emmett,
... Nightingale's choice Amber Cowan's choice: Paula Rego Picture Gallery Amber Cowan's best nationwide shows ...
2001 - Gale Group | TDA
Benoı̂t Rousseau, Arezki K. Boukerma, Julie Henriques, Romain Cohen, Olivier Lucidarme, Christophe Borg, Christophe Tournigand, Stéfano Kim, Jean‐Baptiste Bachet, Thibault Mazard, Christophe Louvet, Benoist Chibaudel, Déwi Vernerey, Thierry André, Anne Hulin,
... chemorefractory metastatic colorectal cancer and treated with regorafenib (REGO) investigated correlations between overall survival (OS) and concentrations (C) of REGO and its active metabolites, M-2 and M-5.55 patients received REGO 160 mg/day for 21 days of a 28-day cycle (NCT02699073). REGO, M-2, M-5 were measured by liquid ... studied the association between OS and Cmin of REGO, M-2 and M-5 at C1 and ... C2/C1 M-2 ratio correlated with C1 REGO+M-2+M-5 (Csum; P = 0.006). ... in patients with metastatic colorectal cancer treated by REGO. OS and safety were favourable when C1 REGO+ ...
Tópico(s): Hepatocellular Carcinoma Treatment and Prognosis
2022 - Elsevier BV | European Journal of Cancer
... 2 Sept. 1643. f.21. 7. Inacio do Rego Barreto, Provedor Mor da Fazenda Real in the ...
1729 - Gale Group | SASII
... shifts of the information revolution and reinventing government (REGO) by examining the role of information technology (IT) in the REGO movement. The authors question three implicit assumptions made by REGO adherents about the role of IT in REGO: that IT is necessary for REGO to take place, that the actual adoption and ... IT is an indicator of the success of REGO, and that the adoption of IT is something ... to be particularly problematic. The authors conclude that REGO is a process rather than an outcomeŠmuch like ...
Tópico(s): Local Government Finance and Decentralization
2000 - SAGE Publishing | Social Science Computer Review
... 2 Sept. 1643. f.21. 7. Inacio do Rego Barreto, Provedor Mor da Fazenda Real in the ...
1729 - Gale Group | SASII
Produção Nacional
Revisado por pares
Severino Jefferson Ribeiro da Silva, Caroline Targino Alves da Silva, Renata Pessôa Germano Mendes, Lindomar Pena,
... IAM), Oswaldo Cruz Foundation (Fiocruz), Avenida Professor Moraes Rego, Recife, Pernambuco, BrazilSearch for more papers by this ... IAM), Oswaldo Cruz Foundation (Fiocruz), Avenida Professor Moraes Rego, Recife, Pernambuco, BrazilSearch for more papers by this ... IAM), Oswaldo Cruz Foundation (Fiocruz), Avenida Professor Moraes Rego, Recife, Pernambuco, BrazilSearch for more papers by this ... IAM), Oswaldo Cruz Foundation (Fiocruz), Avenida Professor Moraes Rego, Recife, Pernambuco, Brazil Correspondence Lindomar Pena, Department of ...
Tópico(s): Viral gastroenteritis research and epidemiology
2020 - Wiley | Journal of Medical Virology
... 2 Sept. 1643. f.21. 7. Inacio do Rego Barreto, Provedor Mor da Fazenda Real in the ...
1729 - Gale Group | SASII
Nick Pavlakis, Kohei Shitara, Katrin Marie Sjoquist, Andrew Martin, Anthony Jaworski, Sonia Yip, Yung‐Jue Bang, Thierry Alcindor, Christopher J. O’Callaghan, Niall C. Tebbutt, Andrew Strickland, Sun Young Rha, Keun‐Wook Lee, John Zalcberg, Timothy Price, John Simes, David Goldstein,
... has limited options after second-line therapy. Regorafenib (Rego), an oral multi-targeted tyrosine kinase inhibitor (TKI) ... 2735). INTEGRATE IIa was designed to examine if Rego improves overall survival (OS). Methods: Double-blind placebo-controlled phase 3 trial comparing Rego + best supportive care (BSC) vs PBO + BSC using ... countries:157 from Asia (Korea, Taiwan, Japan);169 Rego and 82 PBO. After 238 events, median OS (in months) for Rego vs PBO was 4.5 vs 4.0 ( ... 0.56 to 0.87]; p = 0.001). Rego toxicity was similar to previously reported. Conclusions: Rego ...
Tópico(s): Lung Cancer Treatments and Mutations
2023 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
... 2 Sept. 1643. f.21. 7. Inacio do Rego Barreto, Provedor Mor da Fazenda Real in the ...
1729 - Gale Group | SASII
Jorge M.A. Oliveira, Jorge Gonçalves,
... M.R. Nicholls D.G. Ellerby L.M. Rego A.C. J. Neurosci. 2006; 26: 11174-11186Crossref ... M.R. Nicholls D.G. Ellerby L.M. Rego A.C. J. Neurosci. 2006; 26: 11174-11186Crossref ... M. Jekabsons M.B. Chen S. Lin A. Rego A.C. Goncalves J. Ellerby L.M. Nicholls ... 50 nm TMRM+ (quench mode) (14Ward M.W. Rego A.C. Frenguelli B.G. Nicholls D.G. ... M.R. Nicholls D.G. Ellerby L.M. Rego A.C. J. Neurosci. 2006; 26: 11174-11186Crossref ... M.R. Nicholls D.G. Ellerby L.M. Rego A.C. J. Neurosci. 2006; 26: 11174-11186Crossref ... invariant with matrix TMRM+ concentration (14Ward M.W. Rego A.C. Frenguelli B.G. Nicholls D.G. ...
Tópico(s): Neuroscience and Neuropharmacology Research
2008 - Elsevier BV | Journal of Biological Chemistry
... 2 Sept. 1643. f.21. 7. Inacio do Rego Barreto, Provedor Mor da Fazenda Real in the ...
1729 - Gale Group | SASII
This article analyses Paula Rego's 'visual rhetoric' as a transgressive aesthetics that is construed as a political satire addressed at dogmatic truths and homologic universes. Rego's 'aesthetics of danger', as she calls it, ... down and reversing the established order of things', Rego articulates her position in art as occupying an 'ideologically strategic terrain'. I argue that Rego's appropriation of high art is simultaneously subversive and parodic. Like Alice, Rego enters Wonderland 'through the back door', upsetting law ...
Tópico(s): Literature, Culture, and Criticism
2001 - Taylor & Francis | Textual Practice
Srikumar Sen, Boxing Correspondent, Executive Editor David Brewerton, Nicholas Wood and Sam Kiley, Frances Gibb, Legal Affairs Correspondent, Tom Pendry, Chris Petit, Graham Rock, Nick Nuttall, J. F. Storey, David J. Bellamy, Anatol Lieven, Patricia Davies, William Stephens, Michael Hendrie Astronomy Correspondent, Vijitha Yapa, Pearce Wright, Andrew Morgan, Gordon Allan, Philip Howard, Jonathon Porritt, Director, Ian Murray, Michael Binyon, Eric Mensforth, Mandarin (Michael Phillips), Richard Evans, Media Editor, Carol Leonard, Srikumar Sen, Richard Eaton, Colin Narbrough, Bernard Levin, Colin McIntyre, Henry Gee, Mitchell Platts, Sam Kiley Higher Education Reporter, Michael Hornsby and Andrew McEwen, Roland Rudd, Employment Affairs Reporter, Richard Ford Political Correspondent, Louise Taylor, Douglas Broom and Sam Kiley, M. W. Tuck, Michael Evans, Defence Correspondent, Elizabeth Wardle, Rosemary Unsworth, Martin Fletcher, Political Reporter, Shona Crawford Poole, Travel Editor, Caroline Berman, R. Jupe, David Hands, Barry Fantoni, Charles Bremner, L. A. C. Ashby (Head Master), Woodrow Wyatt, Richard Turner, Richard Thomson, Banking Correspondent, Martin Fletcher Political Reporter, Norman de Mesquita, Wolfgang M?nchau, Leslie Tilley, Roddy MacKenzie, Edward Fennell, Andrew Hislop, Paul Vallely, Robert Kirley, Sydney Friskin, Nicholas Harling, Robin Oakley Political Editor, Tim Jones Employment Affairs Correspondent, Mitchell Platts Golf Correspondent, Philip Webster, Chief Political Correspondent, Kerry Gill, Peter Davalle, Alan C. Charters, John Russell Taylor, Peter Dear and Jane Rackham, Yuri Matischen, Steve Acteson, Peter Bryan, Sheila Gunn, Political Staff, John Blunsden, David Young, Energy Correspondent, Andrew Pollack, Barry Pickthall, Irving Wardle, Ian Ross, Frederick Lawton, Darrell Ince, Geoffrey Foster, Richard Bassett, H. I. Arnold, Derek Harris, Industrial Editor, John Wardle and Ian Ross, Rodney Hobson, David Hands Rugby Correspondent, Denzil Walton, David Brewerton, Geof Wheelwright, John Goodbody, David Young, Ian Smith, Christopher Walker, Mandarin, Srikumar Sen Boxing Correspondent, Marcin Krol, Matthew Parris, Paul Newman, Charles Knevitt, Liz Smith, Sarah Jane Checkland Art Market Correspondent, Christopher Walker, Middle East Correspondent, Michael Seely, Keith Blackmore, Michael Clark and Geoffrey Foster, Tony Dawe, D. J. Anderson, A. C. Campbell, Bernardine Coverley, David Walker, David Sinclair, Stephen Pettitt, Henry Rowan-Robinson, Michael Horsnell, Robert Kee, Bailey Morris, David Hardy, Pat Butcher Athletics Correspondent, Louise Mollo, Chris Moore, Derek Harris Industrial Editor, Mike Ward, Colin Campbell, David Hands, Rugby Correspondent, Michael Llanos, Vivien Goldsmith, Family Money Editor, Lionel Read,
... Council A brush with the sinister Galleries Paula Rego Jennifer Bartlett Rosemarie Trockel, Katharina Fritsch Comedy with ...
1988 - Gale Group | TDA
Steven Attia, Vanessa Bolejack, Kristen N. Ganjoo, Suzanne George, Mark Agulnik, Daniel A. Rushing, Elizabeth T. Loggers, Michael B. Livingston, Jennifer Wright, Sant P. Chawla, Scott H. Okuno, Denise K. Reinke, Richard F. Riedel, Lara E. Davis, Christopher W. Ryan, Robert G. Maki,
... on a single arm, phase II trial of REGO in advanced EWS. Methods: EWS pts (age > 18, ... Prior oral kinase inhibitors were not allowed. Initial REGO dose was 160 mg PO QD x21 q28d. ... reduction, most commonly hypophosphatemia (n = 7); 2 stopped REGO for toxicity. There was 1 death in the 30 day post study period, not REGO related. Median dose at study end: 140 mg ( ... reached. Conclusions: The substudy met its primary endpoint. REGO toxicity was similar to that seen previously. Enrollment ... may elucidate which EWS patients may benefit from REGO. Clinical trial information: NCT02048371.
Tópico(s): Colorectal Cancer Treatments and Studies
2017 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
... 2 Sept. 1643. f.21. 7. Inacio do Rego Barreto, Provedor Mor da Fazenda Real in the ...
1729 - Gale Group | SASII
Xiang Li, Guangwei He, Feng Su, Zhaoxing Chu, Leiming Xu, Yazhong Zhang, Jianping Zhou, Yang Ding,
... tumor recurrence. Thus, we aimed to develop regorafenib (REGO)-loaded poly (lactide-co-glycolide) (PLGA) microspheres that ... limit proangiogenic responses following TACE in HCC treatment. REGO-loaded PLGA microspheres were prepared using the emulsion- ... spectra and XRD were applied to confirming sufficient REGO entrapment. The in vitro release profiles demonstrated sustained ... than 30 d To confirm the role of REGO-loaded microspheres in TACE, the cell cytotoxic activity ... cells in vitro. Pharmacokinetics preliminary studies exhibited that REGO could be sustainably released from microspheres for more ...
Tópico(s): Liver physiology and pathology
2020 - Elsevier BV | Asian Journal of Pharmaceutical Sciences
... 2 Sept. 1643. f.21. 7. Inacio do Rego Barreto, Provedor Mor da Fazenda Real in the ...
1729 - Gale Group | SASII
Jingjun Huang, Yongjian Guo, Wensou Huang, Xiaotao Hong, Yi Quan, Liteng Lin, Jingwen Zhou, Licong Liang, Yaqin Zhang, Juan Zhou, Mingyue Cai, Kangshun Zhu,
... regorafenib combined with anti-PD-1 antibody sintilimab (rego-sintilimab) as a second-line treatment for advanced ... evaluated consecutive patients with advanced HCC who received rego-sintilimab (rego-sintilimab group) or regorafenib alone (regorafenib group) as ... patients were included in the study: 58 received rego-sintilimab and 55 received regorafenib. The rego-sintilimab group had higher ORR (36.2% vs ... PFS. Subgroup analyses showed a survival benefit of rego-sintilimab in patients with NLR ≤ 3.6 (hazard ...
Tópico(s): Hepatitis B Virus Studies
2022 - Dove Medical Press | Journal of Hepatocellular Carcinoma
... 2 Sept. 1643. f.21. 7. Inacio do Rego Barreto, Provedor Mor da Fazenda Real in the ...
1729 - Gale Group | SASII