OECD iLibrary
Provisional Act to Regulate the Relations Between the Proprietors of Landed Estates and the Rural Population of Free Laborers, 1849. Entry 1164, Box ...
1849 - Gale Group | SASII
Yuehua Wei, Chi Kwan Tsang, Xiao-Feng Zheng,
... is necessary for TOR complex 1 (TORC1) to regulate the synthesis of 5S ribosomal RNA and transfer ... localization is inhibited by TORC1, indicating that TORC1 regulates nucleoplasm-to-nucleolus transport of Maf1. Finally, we ... in vivo and phosphorylates Maf1 in vitro, and regulates Maf1 nucleoplasm-to-nucleolus translocation. Together, these observations ... confer rapamycin resistance (Zheng et al, 1995). TORC1 regulates a broad spectrum of growth-related processes including ... with rDNA chromatins is crucial for TORC1 to regulate 35S rDNA transcription. However, the significance of TORC1 ...
Tópico(s): RNA modifications and cancer
2009 - Springer Nature | The EMBO Journal
Provisional Act to Regulate the Relations Between the Proprietors of Landed Estates and the Rural Population of Free Laborers, 1849. Entry 1164, Box ...
1849 - Gale Group | SASII
Kristina Kligys, Jonathan Jones,
... explain how this unique gelsolin family member might regulate both stable keratinocyte adhesion and motility. Wound healing ... explain how this unique gelsolin family member might regulate both stable keratinocyte adhesion and motility. Ten years ... G. Deposition of laminin 5 in epidermal wounds regulates integrin signaling and adhesion.Curr Opin Cell Biol. ... α6β4 integrin in the modulation of signals that regulate keratinocyte migration (Margadant et al., 2009Margadant C. Raymond ... N. Hopkinson S.B. et al.Integrin beta4 regulates migratory behavior of keratinocytes by determining laminin-332 ...
Tópico(s): Skin and Cellular Biology Research
2009 - Elsevier BV | Journal of Investigative Dermatology
Provisional Act to Regulate the Relations Between the Proprietors of Landed Estates and the Rural Population of Free Laborers, 1849. Entry 1164, Box ...
1849 - Gale Group | SASII
... first indication that inhibitory second signals (coinhibitory) could regulate T-cell tolerance. While the B7-1/B7- ... work has revealed that this pathway not only regulates the responses of naive T cells but also ... and the pathways defined by these new members regulate the activation, inhibition, and fine-tuning of T- ... family members suggests that they may function to regulate T-cell activation and/or tolerance in non- ... cells (TFH), a unique T-cell subset that regulates germinal center reactions and humoral immunity. Recent studies ...
Tópico(s): Immunotherapy and Immune Responses
2009 - Wiley | Immunological Reviews
Provisional Act to Regulate the Relations Between the Proprietors of Landed Estates and the Rural Population of Free Laborers, 1849. Entry 1164, Box ...
1849 - Gale Group | SASII
Il‐Ha Lee, Craig Campbell, Sung‐Hee Song, Margot L. Day, Sharad Kumar, David I. Cook, Anuwat Dinudom,
... protein of caveolae, caveolin-1 (Cav-1), down-regulates the activity and membrane surface expression of ENaC. ... protein of caveolae, caveolin-1 (Cav-1), down-regulates the activity and membrane surface expression of ENaC. ... 11886-11890Crossref PubMed Scopus (71) Google Scholar) up-regulate activity of ENaC by inhibiting Nedd4-2. Although ... PubMed Scopus (847) Google Scholar). Cav-1 also regulates the activity and membrane expression of ion channels ... C1351Crossref PubMed Google Scholar) and several proteins that regulate activity of ENaC, such as Nedd4 (37Plant P. ...
Tópico(s): Erythrocyte Function and Pathophysiology
2009 - Elsevier BV | Journal of Biological Chemistry
Provisional Act to Regulate the Relations Between the Proprietors of Landed Estates and the Rural Population of Free Laborers, 1849. Entry 1164, Box ...
1849 - Gale Group | SASII
Taeho Kim, Barbara L. Hempstead,
... 2009free access NRH2 is a trafficking switch to regulate sortilin localization and permit proneurotrophin-induced cell death ... show that the mammalian p75NTR homologue NRH2 critically regulates the expression of sortilin on the neuronal cell ... kinases and the neurotrophin receptor p75NTR. Trk receptors regulate neuronal survival, differentiation, and synaptic plasticity through well ... et al, 2007). However, the molecular mechanisms that regulate sortilin localization during neuronal development are unknown. A ...
Tópico(s): Signaling Pathways in Disease
2009 - Springer Nature | The EMBO Journal
Provisional Act to Regulate the Relations Between the Proprietors of Landed Estates and the Rural Population of Free Laborers, 1849. Entry 1164, Box ...
1849 - Gale Group | SASII
Jana Mazelova, Lisa Astuto-Gribble, Hiroki Inoue, Beatrice M. Tam, Eric Schonteich, Rytis Prekeris, Orson L. Moritz, Paul A. Randazzo, Dusanka Deretic,
... in rhodopsin binds the small GTPase Arf4 and regulates its association with the trans-Golgi network (TGN), ... Arf4 and functions as an Arf4 effector that regulates budding of post-TGN carriers, along with FIP3 ... et al, 2008). In retinal rod photoreceptors, Rab8 regulates the biogenesis of cilia-derived sensory organelles, the ... VxPx motif engages Arf4 at the TGN to regulate RTC budding. (A) Diagram of the photoreceptor cell. ... et al, 2005). The Arf family members generally regulate membrane trafficking, lipid metabolism, organelle morphology and cytoskeleton ...
Tópico(s): Cellular transport and secretion
2009 - Springer Nature | The EMBO Journal
Provisional Act to Regulate the Relations Between the Proprietors of Landed Estates and the Rural Population of Free Laborers, 1849. Entry 1164, Box ...
1849 - Gale Group | SASII
Yunjuan Zhu, Yuanjun Wu, Jae Il Kim, Zhimin Wang, Yehia Daaka, Zhongzhen Nie,
... AGAP2 is an Arf GTPase-activating protein that regulates endosomal trafficking and is overexpressed in different human ... protein-like domain. Our results indicate that AGAP2 regulates the FAK activity and the focal adhesion disassembly ... AGAP2 is an Arf GTPase-activating protein that regulates endosomal trafficking and is overexpressed in different human ... protein-like domain. Our results indicate that AGAP2 regulates the FAK activity and the focal adhesion disassembly ... β5 strand and β6 strand. The Arf GAPs regulate membrane trafficking and remodeling of the actin cytoskeleton ( ...
Tópico(s): Cellular transport and secretion
2009 - Elsevier BV | Journal of Biological Chemistry
Provisional Act to Regulate the Relations Between the Proprietors of Landed Estates and the Rural Population of Free Laborers, 1849. Entry 1164, Box ...
1849 - Gale Group | SASII
Zhenglong Wang, Yosuke Kumamoto, Ping Wang, Xiaoqing Gan, David M. Lehmann, Alan V. Smrcka, Lauren Cohn, Akiko Iwasaki, Lin Li, Dianqing Wu,
... to the Gi family of G proteins to regulate leukocyte chemotaxis. Previous studies have established that the Rho family of small GTPases regulates leukocyte migration (1Ridley A.J. J. Cell Sci. ... studied Rho small GTPases. In myeloid cells, Cdc42 regulates directionality by directing where F-actin and lamellipodia are formed, and Rac regulates F-actin formation in the lamellipodia, which provides ... 408) Google Scholar). On the other hand, RhoA regulates the formation and contractility of the actomyosin structure ...
Tópico(s): Cytokine Signaling Pathways and Interactions
2009 - Elsevier BV | Journal of Biological Chemistry
Provisional Act to Regulate the Relations Between the Proprietors of Landed Estates and the Rural Population of Free Laborers, 1849. Entry 1164, Box ...
1849 - Gale Group | SASII
Toshinori Aoyagi, Taka‐aki Koshimizu, Akito Tanoue,
... by affecting V2/aquaporin 2 function. Thus, AVP regulates blood pressure and volume via V1aR by exerting ... by affecting V2/aquaporin 2 function. Thus, AVP regulates blood pressure and volume via V1aR by exerting ... possible mechanism(s) by which AVP/V1aR may regulate blood pressure based on our studies with V1aR−/− ... the possible mechanism(s) by which AVP/V1aR regulates blood pressure, we analyzed V1aR−/− mice and found ... T. Izumi Y. Hiroyama M. et al.Vasopressin regulates the renin-angiotensin-aldosterone system via V1a receptors ...
Tópico(s): Electrolyte and hormonal disorders
2009 - Elsevier BV | Kidney International
Provisional Act to Regulate the Relations Between the Proprietors of Landed Estates and the Rural Population of Free Laborers, 1849. Entry 1164, Box ...
1849 - Gale Group | SASII
Young-Sil Yoon, Woo-Young Seo, Minwoo Lee, Seong‐Tae Kim, Seung‐Hoi Koo,
... the salt-inducible kinase (SIK) family of proteins regulates the hepatic lipogenesis by modulating SREBP-1c activity. ... the salt-inducible kinase (SIK) family of proteins regulates the hepatic lipogenesis by modulating SREBP-1c activity. ... a member of the AMPK-related kinases, directly regulates SREBP-1c-dependent hepatic lipogenesis. Overexpression of SIK1 ... with SIK1 overexpression, suggesting that SIK1 could also regulate lipogenic gene transcription. Expression of Srebf1, a gene ... blot analysis (Fig. 1C), showing that SIK could regulate lipogenic gene expression in an in vivo setting. ...
Tópico(s): Liver Disease Diagnosis and Treatment
2009 - Elsevier BV | Journal of Biological Chemistry
Provisional Act to Regulate the Relations Between the Proprietors of Landed Estates and the Rural Population of Free Laborers, 1849. Entry 1164, Box ...
1849 - Gale Group | SASII
Sara A. Wickström, Katarzyna Chmielarska Masoumi, Saadi Khochbin, Reinhard Fässler, Ramin Massoumi,
Article5 November 2009Open Access CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin Sara A Wickström Sara A Wickström Department of Molecular ... is a deubiquitinating enzyme that was shown to regulate cell proliferation, cell survival and inflammatory responses, mainly ... interacts with HDAC6 in the midbody where it regulates the rate of cytokinesis in a deubiquitinase-independent ... these results identify a mechanism by which CYLD regulates cell proliferation at distinct cell-cycle phases. Introduction ...
Tópico(s): Histone Deacetylase Inhibitors Research
2009 - Springer Nature | The EMBO Journal
Provisional Act to Regulate the Relations Between the Proprietors of Landed Estates and the Rural Population of Free Laborers, 1849. Entry 1164, Box ...
1849 - Gale Group | SASII
Jian Xie, Tao Wu, Ke Xu, Ivan Huang, Ondine Cleaver, Chou-Long Huang,
... unknown. Dozens of genes have been identified that regulate the processes of vasculogenesis, angiogenesis, and artery-vein ... notch signaling by the Coup-TFII transcription factor regulates vein identity.Nature. 2005; 435: 98-104Crossref PubMed ... RD Forbush B Aronson PS Lifton RP WNK4 regulates apical and basolateral Cl− flux in extrarenal epithelia. ... RD Forbush B Aronson PS Lifton RP WNK4 regulates apical and basolateral Cl− flux in extrarenal epithelia. ... 2064-2069Crossref PubMed Scopus (150) Google Scholar WNK1 regulates sodium channel ENaC and the thiazide-sensitive sodium- ...
Tópico(s): Ion Transport and Channel Regulation
2009 - Elsevier BV | American Journal Of Pathology
Provisional Act to Regulate the Relations Between the Proprietors of Landed Estates and the Rural Population of Free Laborers, 1849. Entry 1164, Box ...
1849 - Gale Group | SASII
Yongwei Zhang, Tamara L. Jones, Scott E. Martin, Natasha J. Caplen, Yves Pommier,
... γ-H2AX. Further studies showed that CPT up-regulates both RRM1 and RRM2 mRNA and protein levels ... Chk1 activation, mediated by ATM and ATR, up-regulates RRM2 expression through the E2F1 transcription factor. Up- ... γ-H2AX. Further studies showed that CPT up-regulates both RRM1 and RRM2 mRNA and protein levels ... Chk1 activation, mediated by ATM and ATR, up-regulates RRM2 expression through the E2F1 transcription factor. Up- ... PubMed Scopus (842) Google Scholar). DNA damage also regulates RNR activity. In budding yeast RNR up-regulation ( ...
Tópico(s): Acute Myeloid Leukemia Research
2009 - Elsevier BV | Journal of Biological Chemistry
Provisional Act to Regulate the Relations Between the Proprietors of Landed Estates and the Rural Population of Free Laborers, 1849. Entry 1164, Box ...
1849 - Gale Group | SASII
... emerging evidence suggests that Rho and ROCK can regulate smooth muscle contraction by controlling activities of ion ... delineate the molecular mechanisms by which Rho/ROCK regulates KDR channels. Their key finding is that actin ... studies have shown that Rho/ROCK also negatively regulates other types of potassium channels, such as ether- ... 9). These data indicate that Rho/ROCK can regulate different types of ion channels and that the ... G protein-coupled receptor or mechanosensitive signaling to regulate ion channels. Although the underlying molecular mechanisms are ...
Tópico(s): Ion channel regulation and function
2009 - American Physical Society | AJP Heart and Circulatory Physiology
Provisional Act to Regulate the Relations Between the Proprietors of Landed Estates and the Rural Population of Free Laborers, 1849. Entry 1164, Box ...
1849 - Gale Group | SASII