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Artigo Acesso aberto Revisado por pares

Atsushi Sofuni, Yasutsugu Asai, Takayoshi Tsuchiya, Kentaro Ishii, Reina Tanaka, Ryosuke Tonozuka, Mitsuyoshi Honjo, Shuntaro Mukai, Kazumasa Nagai, Kenjiro Yamamoto, Yukitoshi Matsunami, Takashi Kurosawa, Hiroyuki Kojima, Toshihiro Homma, Hirohito Minami, Ryosuke Nakatsubo, Noriyuki Hirakawa, H. Miyazawa, Yuichi Nagakawa, Akihiko Tsuchida, Takao Itoi,

High-intensity focused ultrasound (HIFU) is a novel advanced therapy for unresectable pancreatic cancer (PC). HIFU therapy with chemotherapy is being promoted as a novel method to control local advancement by tumor ablation. We evaluated the therapeutic effects of HIFU therapy in locally advanced and metastatic PC. PC patients were treated with HIFU as an optional local therapy and systemic chemotherapy. The FEP-BY02 (Yuande Bio-Medical Engineering) HIFU device was used under ultrasound guidance. Of ...

Tópico(s): Cancer Cells and Metastasis

2021 - Multidisciplinary Digital Publishing Institute | Current Oncology

Artigo Acesso aberto Revisado por pares

Hirohito Minami, Shuntaro Mukai, Atsushi Sofuni, Takayoshi Tsuchiya, Kentaro Ishii, Reina Tanaka, Ryosuke Tonozuka, Mitsuyoshi Honjo, Kenjiro Yamamoto, Kazumasa Nagai, Yukitoshi Matsunami, Yasutsugu Asai, Takashi Kurosawa, Hiroyuki Kojima, Toshihiro Homma, Takao Itoi,

Although Spy DS (SpyGlass DS Direct Visualization System) is considered to be useful for the diagnosis of bile duct strictures and the treatment of bile duct stones, there is limited data to date validating its efficacy. We hence retrospectively evaluated the clinical outcomes of the use of Spy DS in a large number of patients. A total of 183 patients who underwent Spy DS-guided procedures for indeterminate bile duct strictures (n = 93) and bile duct stones (n = 90) were analyzed retrospectively. All patients ( ...

Tópico(s): Pediatric Hepatobiliary Diseases and Treatments

2021 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine

Artigo Acesso aberto Revisado por pares

Takao Itoi, Yukitoshi Matsunami, Atsushi Sofuni, Takayoshi Tsuchiya, Kentaro Ishii, Reina Tanaka, Ryosuke Tonozuka, Mitsuyoshi Honjo, Shuntaro Mukai, Kazumasa Nagai, Kenjiro Yamamoto, Yasutsugu Asai, Takashi Kurosawa, Hiroyuki Kojima, Eri Joyama, Yuichi Nagakawa,

EUS-guided biliary drainage (EUS-BD) has recently been used for the treatment of not only malignant pancreaticobiliary diseases, but also for benign diseases. In most previous studies, EUS-BD was performed using a fully covered self-expandable metallic stent (SEMS), and data focusing on the usability of plastic stents for benign diseases are limited. We previously developed a plastic stent dedicated to EUS-guided hepaticoenterostomy (EUS-HES), and achieved favorable results in a feasibility study, ...

Tópico(s): Pancreatitis Pathology and Treatment

2021 - Lippincott Williams & Wilkins | Endoscopic Ultrasound

Artigo Acesso aberto Revisado por pares

Takao Itoi, Ryosuke Nakatsubo, Kenjiro Yamamoto, Atsushi Sofuni, Takayoshi Tsuchiya, Kentaro Ishii, Reina Tanaka, Ryosuke Tonozuka, Shuntaro Mukai, Kazumasa Nagai, Hiroshi Yamaguchi, Yuichi Nagakawa,

EUS-guided fine-needle biopsy (EUS-FNB) is considered a safe and useful method for preoperative diagnosis of resectable solid pancreatic masses. However, needle tract seeding (NTS) after EUS-FNB has recently been reported, which may affect long-term outcome. The aim of this study was to evaluate NTS after EUS-FNB.We reviewed 73 resected cases that underwent preoperative EUS-FNB for a pancreatic tumor from April 2014 to March 2016 and evaluated the utility and adverse events of EUS-FNB based on consecutively ...

Tópico(s): Neuroendocrine Tumor Research Advances

2021 - Lippincott Williams & Wilkins | Endoscopic Ultrasound

Artigo Revisado por pares

Majid A. Almadi, Takao Itoi, Jong Ho Moon, Mahesh Kumar Goenka, Dong Wan Seo, Rungsun Rerknimitr, James Y. Lau, Amit Maydeo, Jong Kyun Lee, Nam Q. Nguyen, Saad Khalid Niaz, Randhir Sud, Tiing Leong Ang, Abdulrahman Aljebreen, Benedict M. Devereaux, Rakesh Kochhar, J Reichenberger, Ichiro Yasuda, Arthur J. Kaffes, Masayuki Kitano, Joyce Peetermans, Pooja G. Goswamy, Matthew Rousseau, D. Nageshwar Reddy, Sundeep Lakhtakia, Yun Nah Lee, Vijay Kumar, Kentaro Kamada, Reina Tanaka, Ryosuke Tonozuka, Akihiko Tsuchida, Tae Jun Song, Mohan K. Ramchandani,

Abstract Background Peroral cholangioscopy (POCS) of indeterminate biliary strictures aims to achieve a diagnosis through visual examination and/or by obtaining targeted biopsies under direct visualization. In this large, prospective, multinational, real-life experience of POCS-guided evaluation of indeterminate biliary strictures, we evaluated the performance of POCS in this difficult-to-manage patient population. Methods This prospective registry enrolled patients, with indeterminate biliary strictures ...

Tópico(s): Biliary and Gastrointestinal Fistulas

2020 - Thieme Medical Publishers (Germany) | Endoscopy

Artigo Acesso aberto Revisado por pares

Ryosuke Tonozuka, Takao Itoi, Naoyoshi Nagata, Hiroyuki Kojima, Atsushi Sofuni, Takayoshi Tsuchiya, Kentaro Ishii, Reina Tanaka, Yuichi Nagakawa, Shuntaro Mukai,

The application of artificial intelligence to clinical diagnostics using deep learning has been developed in recent years. In this study, we developed an original computer-assisted diagnosis (CAD) system using deep learning analysis of EUS images (EUS-CAD), and assessed its ability to detect pancreatic ductal carcinoma (PDAC), using control images from patients with chronic pancreatitis (CP) and those with a normal pancreas (NP).A total of 920 endosonographic images were used for the training and 10- ...

Tópico(s): AI in cancer detection

2020 - Wiley | Journal of Hepato-Biliary-Pancreatic Sciences

Revisão Acesso aberto Revisado por pares

Satoshi Shimai, Kenjiro Yamamoto, Atsushi Sofuni, Takayoshi Tsuchiya, Kentaro Ishii, Reina Tanaka, Ryosuke Tonozuka, Mitsuyoshi Honjo, Shuntaro Mukai, Mitsuru Fujita, Kazumasa Nagai, Yasutsugu Asai, Yukitoshi Matsunami, Takashi Kurosawa, Hiroyuki Kojima, H Honma, Hiroto Minami, Hiroshi Yamaguchi, Takao Itoi,

We herein report three cases of patients with an ampullary neuroendocrine tumor (NET), who underwent endoscopic papillectomy (EP). No tumor recurrence or metastasis was detected in the patients for more than two years after EP. Generally, surgical resection is recommended for ampullary NETs by the European Neuroendocrine Tumor Society. However, as EP is less invasive than surgical resection, there are some reports of low-grade small ampullary NETs curatively treated by EP with long-term follow-up. ...

Tópico(s): Lung Cancer Research Studies

2020 - The Japanese Society of Internal Medicine | Internal Medicine

Artigo Acesso aberto Revisado por pares

Eisuke Iwasaki, Kazuhiro Minami, Takao Itoi, Kenjiro Yamamoto, Shujiro Tsuji, Atsushi Sofuni, Takayoshi Tsuchiya, Reina Tanaka, Ryosuke Tonozuka, Yujiro Machida, Yoichi Takimoto, Hiroki Tamagawa, Tadashi Katayama, Shintaro Kawasaki, Takashi Seino, Masayasu Horibe, Seiichiro Fukuhara, Minoru Kitago, Haruhiko Ogata, Takanori Kanai∥,

Endoscopic papillectomy is increasingly being used for ampullary adenoma treatment. However, it remains challenging despite increased safety with treatment advances. The ideal power output and electrosurgical current mode for mucosal resection are not established. We aimed to identify the ideal electrical pulse for use during resection.This pilot randomized, single-blind, prospective, multicenter trial, recruited patients with ampullary adenomas and conventional anatomy who were scheduled to undergo ...

Tópico(s): Esophageal and GI Pathology

2019 - Wiley | Digestive Endoscopy

Artigo Acesso aberto Revisado por pares

Takao Itoi, Mitsuyoshi Honjo, Takayoshi Tsuchiya, Reina Tanaka, Ryosuke Tonozuka, Shuntaro Mukai, Atsushi Sofuni, Yuichi Nagakawa, Hidenori Iwasaki, Takanori Kanai∥,

Successful tract dilation is one of the most important steps to accomplish EUS-guided drainage. Although mechanical dilation is safer than electrocautery dilation, no dedicated mechanical dilator (MD) is currently available. Thus, we developed a new ultra-tapered MD for EUS-guided drainage. This study aimed to evaluate the safety and usefulness of this novel MD.Consecutive patients who underwent EUS-guided hepaticogastrostomy (EUS-HGS) or EUS-guided pancreatic duct drainage (EUS-PD) at two centers ...

Tópico(s): Pediatric Hepatobiliary Diseases and Treatments

2018 - Lippincott Williams & Wilkins | Endoscopic Ultrasound

Artigo Acesso aberto Revisado por pares

Kenjiro Yamamoto, Atsushi Sofuni, Takayoshi Tsuchiya, Kentaro Ishii, Shujiro Tsuji, Reina Tanaka, Ryosuke Tonozuka, Mitsuyoshi Honjo, Shuntaro Mukai, Mitsuru Fujita, Yasutsugu Asai, Yukitoshi Matsunami, Yuichi Nagakawa, Hiroshi Yamaguchi, Takao Itoi,

Objective Endoscopic papillectomy (EP) has been recognized to be a safe and reliable treatment modality for ampullary adenomas. The purpose of this study was to determine the safety and efficacy of endoscopic piecemeal resection for laterally spreading ampullary adenomas and to compare these findings with a control population of smaller conventional ampullary tumors treated in the same time period. Methods Between May 1999 and September 2015, 136 patients underwent EP at Tokyo Medical University ...

Tópico(s): Cholangiocarcinoma and Gallbladder Cancer Studies

2018 - The Japanese Society of Internal Medicine | Internal Medicine

Artigo Acesso aberto Revisado por pares

Takao Itoi, Shuntaro Mukai, Hiroshi Yamaguchi, Atsushi Sofuni, Takayoshi Tsuchiya, Reina Tanaka, Ryosuke Tonozuka, Mitsuyoshi Honjo, Mitsuru Fujita, Kenjiro Yamamoto, Yukitoshi Matsunami, Yasutsugu Asai, Takashi Kurosawa, Yuichi Nagakawa,

Recently, a 22G Franseen needle for EUS-guided fine-needle biopsy (EUS-FNB) with three novel symmetric heels has been developed to adequately obtain a core tissue.All 38 consecutive patients with pancreatic masses who underwent EUS-FNB using a Franseen needle were investigated retrospectively to assess the efficacy and safety of EUS-FNB using the Franseen needle. Then, the EUS-FNB outcomes and histological assessments of the tissue obtained by EUS-FNB using the Franseen needle and EUS-FNA using the ...

Tópico(s): Neuroendocrine Tumor Research Advances

2018 - Lippincott Williams & Wilkins | Endoscopic Ultrasound

Revisão Acesso aberto Revisado por pares

Takao Itoi, Kenjiro Yamamoto, Takayoshi Tsuchiya, Reina Tanaka, Ryosuke Tonozuka, Mitsuyoshi Honjo, Shuntaro Mukai, Mitsuru Fujita, Yasutsugu Asai, Yukitoshi Matsunami, Takashi Kurosawa, Atsushi Sofuni, Yuichi Nagakawa,

Background and Objectives: Recently, a novel EUS-guided biliary drainage (EUS-BD) technique consisting of EUS-guided antegrade stenting and EUS-guided hepaticoenterostomy (EUS-AS+HES) using two conventional metal stents (MS) has been reported to decrease adverse events and maintain longer stent patency for malignant biliary obstruction (MBO). However, only a few limited reports have evaluated this technique. Finally, dedicated plastic stents (PSs) have been developed to perform EUS-HES safely. The aim ...

Tópico(s): Pancreatic and Hepatic Oncology Research

2018 - Lippincott Williams & Wilkins | Endoscopic Ultrasound

Artigo Revisado por pares

Shuntaro Mukai, Takao Itoi, Atsushi Sofuni, Takayoshi Tsuchiya, Reina Tanaka, Ryosuke Tonozuka, Mitsuyoshi Honjo, Mitsuru Fujita, Kenjiro Yamamoto, Yuichi Nagakawa,

Background and Aims Although balloon enteroscopy–assisted ERCP (BE-ERCP) is effective and safe for benign biliary diseases in patients with surgically altered anatomy (SAA), BE-ERCP is not always successful. Recently, EUS-guided antegrade intervention (EUS-AI) by using a 1-stage or 2-stage procedure has been developed for BE-ERCP failure cases. The aim of the present study was to evaluate the outcome of EUS-AI for benign biliary diseases in patients with SAA. Methods Of 48 patients in whom BE-ERCP ...

Tópico(s): Pancreatic and Hepatic Oncology Research

2018 - Elsevier BV | Gastrointestinal Endoscopy

Artigo Acesso aberto Revisado por pares

Yasutsugu Asai, Takao Itoi, Masahiro Sugimoto, Atsushi Sofuni, Takayoshi Tsuchiya, Reina Tanaka, Ryosuke Tonozuka, Mitsuyoshi Honjo, Shuntaro Mukai, Mitsuru Fujita, Kenjiro Yamamoto, Yukitoshi Matsunami, Takashi Kurosawa, Yuichi Nagakawa, Miku Kaneko, Sana Ota, Shigeyuki Kawachi, Motohide Shimazu, Tomoyoshi Soga, Masaru Tomita, Makoto Sunamura,

Detection of pancreatic cancer (PC) at a resectable stage is still difficult because of the lack of accurate detection tests. The development of accurate biomarkers in low or non-invasive biofluids is essential to enable frequent tests, which would help increase the opportunity of PC detection in early stages. Polyamines have been reported as possible biomarkers in urine and saliva samples in various cancers. Here, we analyzed salivary metabolites, including polyamines, using capillary electrophoresis- ...

Tópico(s): Melamine detection and toxicity

2018 - Multidisciplinary Digital Publishing Institute | Cancers

Artigo Revisado por pares

Kenjiro Yamamoto, Takao Itoi, Atsushi Sofuni, Takayoshi Tsuchiya, Reina Tanaka, Ryosuke Tonozuka, Mitsuyoshi Honjo, Shuntaro Mukai, Mitsuru Fujita, Yasutsugu Asai, Yukitoshi Matsunami, Takashi Kurosawa, Hiroshi Yamaguchi, Yuichi Nagakawa,

Endoscopic papillectomy (EP) has been attempted not only for benign lesions but also for early ampullary carcinoma (AC). However, there is still no sufficient evidence or consensus regarding the effectiveness of EP for early AC. Herein, we evaluated the expanding indication of EP for early AC.Between May 1999 and December 2016, 177 patients were diagnosed with ampullary tumor before undergoing EP, and their clinical and histopathological data were analyzed retrospectively.There were 27 Tis-T1a AC ...

Tópico(s): Gallbladder and Bile Duct Disorders

2018 - Wiley | Digestive Endoscopy

Artigo Acesso aberto Revisado por pares

Yukitoshi Matsunami, Takao Itoi, Atsushi Sofuni, Takayoshi Tsuchiya, Kentaro Kamada, Reina Tanaka, Ryosuke Tonozuka, Mitsuyoshi Honjo, Shuntaro Mukai, Mitsuru Fujita, Kenjiro Yamamoto, Yasutsugu Asai, Takashi Kurosawa, Shingo Tachibana, Yuichi Nagakawa,

Endoscopic ultrasonography-guided pancreatic duct drainage (EUS-PD) has been reported as an alternative for failed conventional endoscopic retrograde cholangiopancreatography (ERCP). However, there are few dedicated devices for EUS-PD. Recently, we have developed a new plastic stent dedicated to EUS-PD and have conducted a feasibility study to evaluate its efficacy. In the current study, we evaluated the long-term efficacy of this new plastic stent. Thirty patients (61 ± 14.3 years old, 14 men) with ...

Tópico(s): Pancreatic and Hepatic Oncology Research

2018 - Thieme Medical Publishers (Germany) | Endoscopy International Open

Artigo Revisado por pares

Ryosuke Tonozuka, Takao Itoi, Atsushi Sofuni, Takayoshi Tsuchiya, Kentaro Ishii, Reina Tanaka, Mitsuyoshi Honjo, Shuntaro Mukai, Kenjiro Yamamoto, Mitsuru Fujita, Yasutsugu Asai, Yukitoshi Mastunami, Takashi Kurosawa, Hiroyuki Kojima, Hirofumi Kogure, Yuichi Nagakawa,

Efficacy of cholangioscopy‐assisted lithotripsy for difficult stones such as huge stones, multiple large stones and an impacted stone in patients with non‐altered anatomy has been reported. Herein, we describe peroral direct digital cholangioscopy ( PDCS )‐assisted electrohydraulic lithotripsy ( EHL ) with a new technique in patients with surgically altered anatomy. Five patients received PDCS ‐assisted EHL with the monorail technique due to failed conventional stone extraction. Balloon enteroscope was removed, ...

Tópico(s): Pancreatic and Hepatic Oncology Research

2018 - Wiley | Digestive Endoscopy

Artigo Acesso aberto Revisado por pares

Kenjiro Yamamoto, Takayoshi Tsuchiya, Reina Tanaka, Mitsuyoshi Honjo, Shuntaro Mukai, Yuichi Nagakawa, Takao Itoi,

Afferent loop syndrome is a complication that infrequently occurs after pancreaticoduodenectomy [1]. Complete obstruction occurs which leads to cholangitis, pancreatitis, perforation, and necrosis. In particular, patients with cancer recurrence cannot continue chemotherapy treatment, become debilitated, and may eventually die. Therefore, early and appropriate decompression treatment is needed.

Tópico(s): Esophageal and GI Pathology

2017 - Thieme Medical Publishers (Germany) | Endoscopy

Artigo Acesso aberto Revisado por pares

Takao Itoi, Masahiro Sugimoto, Junko Umeda, Atsushi Sofuni, Takayoshi Tsuchiya, Shujiro Tsuji, Reina Tanaka, Ryosuke Tonozuka, Mitsuyoshi Honjo, Fuminori Moriyasu, Kazuhiko Kasuya, Yuichi Nagakawa, Yuta Abe, Kimihiro Takano, Shigeyuki Kawachi, Motohide Shimazu, Tomoyoshi Soga, Masaru Tomita, Makoto Sunamura,

This study evaluated the clinical use of serum metabolomics to discriminate malignant cancers including pancreatic cancer (PC) from malignant diseases, such as biliary tract cancer (BTC), intraductal papillary mucinous carcinoma (IPMC), and various benign pancreaticobiliary diseases. Capillary electrophoresismass spectrometry was used to analyze charged metabolites. We repeatedly analyzed serum samples (n = 41) of different storage durations to identify metabolites showing high quantitative reproducibility, ...

Tópico(s): Cholangiocarcinoma and Gallbladder Cancer Studies

2017 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences

Artigo Acesso aberto

Kenjiro Yamamoto, Takayoshi Tsuchiya, Takao Itoi, Shujiro Tsuji, Reina Tanaka, Ryosuke Tonozuka, Mitsuyoshi Honjo, Shuntaro Mukai, Kentaro Kamada, Mitsuru Fujita, Yasutsugu Asai, Yukitoshi Matsunami, Yuichi Nagakawa, Hiroshi Yamaguchi, Atsushi Sofuni,

AIMTo evaluate the feasibility and reliability of endoscopic transpapillary bile duct biopsy for the diagnosis of biliary strictures. METHODSA total of 360 patients (241 men) who underwent endoscopic retrograde cholangiopancreatography for biliary strictures with biopsy from April 2012 to 6429

Tópico(s): Pancreatic and Hepatic Oncology Research

2017 - Baishideng Publishing Group | World Journal of Gastroenterology

Artigo Revisado por pares

Reina Tanaka, Takao Itoi, Mitsusyoshi Honjo, Takayoshi Tsuchiya, Toshio Kurihara, Shujiro Tsuji, Ryosuke Tonozuka, Kentato Kamada, Atsushi Sofuni, Shuntaro Mukai,

Recently, a new digital cholangiopancreatoscopy (DCPS) has been developed. The aim of this study is to retrospectively evaluate the utility of new DCPS in patients with pancreaticobiliary diseases.Digital cholangiopancreatoscopy was used in 26 patients (16 men) with pancreaticobiliary diseases that could not be diagnosed and treated by standard endoscopic retrograde cholangiopancreatography (ERCP). The procedures included DCPS-guided tissue sampling and interventions. Technical success and adverse ...

Tópico(s): Pancreatic and Hepatic Oncology Research

2016 - Wiley | Journal of Hepato-Biliary-Pancreatic Sciences

Carta Acesso aberto Revisado por pares

Ryosuke Tonozuka, Takao Itoi, Takayoshi Tsuchiya, Reina Tanaka, Shuntaro Mukai,

EUS-guided biliary drainage (EUS-BD) has become an alternative procedure to percutaneous transhepatic biliary drainage (PTBD) in failed ERCP. Recently, the efficacy and high rate of adverse events of EUS-BD have been reported.1-5 We describe the actual use of EUS-BD in our hospital, one of the largest referral centers of ERCP and interventional EUS in Japan.

Tópico(s): Pediatric Hepatobiliary Diseases and Treatments

2016 - Elsevier BV | Gastrointestinal Endoscopy

Artigo Acesso aberto Revisado por pares

Takao Itoi, Mitsuru Fujita, Nobuhito Ikeuchi, Atsushi Sofuni, Takayoshi Tsuchiya, Kentaro Ishii, Kentaro Kamada, Junko Umeda, Reina Tanaka, Ryosuke Tonozuka, Mitsuyoshi Honjo, Shuntaro Mukai, Fuminori Moriyasu,

There have been few studies to date evaluating the effectiveness of contrast-enhanced endoscopic ultrasound (CE-EUS) for detecting mural nodules in patients with branch duct-type intraductal papillary mucinous neoplasm (BD-IPMN) of the pancreas. We aim to evaluate the effectiveness of CE-EUS for detecting mural nodules in BD-IPMN.Of the 427 BD-IPMN patients, 21 patients (4.9%) in whom the presence of mural nodules was suggested by CE computed tomography (CT) or magnetic resonance imaging (MRI), or in ...

Tópico(s): Gallbladder and Bile Duct Disorders

2016 - Lippincott Williams & Wilkins | Endoscopic Ultrasound

Artigo Revisado por pares

Takao Itoi, Atsushi Sofuni, Takayoshi Tsuchiya, Kentaro Ishii, Nobuhito Ikeuchi, Reina Tanaka, Junko Umeda, Ryosuke Tonozuka, Mitsuyoshi Honjo, Shuntaro Mukai, Takako Takayama, Fuminori Moriyasu,

There are currently no plastic pancreatic duct stents that have been designed for endoscopic ultrasonography (EUS)-guided placement. This study prospectively evaluated the feasibility and efficacy of a new, single-pigtail, plastic stent. Eight patients with main pancreatic duct stricture or stenotic pancreatojejunostomy underwent EUS-guided placement of the pancreatic duct stent. The stent was placed successfully in all cases (8/8). Treatment success was achieved in all cases (8/8). A mild adverse ...

Tópico(s): Gallbladder and Bile Duct Disorders

2015 - Thieme Medical Publishers (Germany) | Endoscopy

Artigo Revisado por pares

Kentaro Ishii, Takao Itoi, Ryosuke Tonozuka, Fumihide Itokawa, Atsushi Sofuni, Takayoshi Tsuchiya, Shujiro Tsuji, Nobuhito Ikeuchi, Kentaro Kamada, Junko Umeda, Reina Tanaka, Mitsuyoshi Honjo, Shuntaro Mukai, Mitsuru Fujita, Fuminori Moriyasu, Todd H. Baron, Takuji Gotoda,

Background and Aims Balloon enteroscopy–assisted ERCP has provided a marked improvement in the success rate of reaching the papilla and consecutive ERCP procedures in patients with surgically altered anatomy in the Roux-en-Y reconstruction setting. However, limited data are available on the outcome of balloon enteroscopy–assisted ERCP in patients with Roux-en-Y anatomy who have naïve papillae. We retrospectively evaluated the feasibility of balloon enteroscopy–assisted ERCP in Roux-en-Y reconstruction ...

Tópico(s): Pancreatic and Hepatic Oncology Research

2015 - Elsevier BV | Gastrointestinal Endoscopy

Artigo Revisado por pares

Ryosuke Tonozuka, Takao Itoi, Takayoshi Tsuchiya, Atsushi Sofuni, Kentaro Ishii, Nobuhito Ikeuchi, Junko Umeda, Reina Tanaka, Shuntaro Mukai, Takuji Gotoda, Fuminori Moriyasu,

Background Currently, few reports exist on EUS-guided hepatic abscess drainage (EUS-HAD) and EUS-guided biloma drainage (EUS-BLD) using a metal stent. Objective We evaluated the technical success rate and efficacy of EUS-HAD and EUS-BLD for patients with hepatic abscess (HA) and infected biloma. Design Retrospective case series. Setting Single tertiary referral medical center. Patients We evaluated 7 HA and 6 infected biloma patients who were treated between August 2013 and August 2014 at Tokyo Medical ...

Tópico(s): Amoebic Infections and Treatments

2015 - Elsevier BV | Gastrointestinal Endoscopy

Artigo Revisado por pares

Shuntaro Mukai, Takao Itoi, Reiko Ashida, Takayoshi Tsuchiya, Nobuhito Ikeuchi, Kentaro Kamada, Reina Tanaka, Junko Umeda, Ryosuke Tonozuka, Nobuyasu Fukutake, Koki Hoshi, Fuminori Moriyasu, Takuji Gotoda, Atsushi Irisawa,

There are currently no prospective, controlled trials of needle puncture speed in EUS-guided FNA (EUS-FNA). In this study, we prospectively evaluated the accuracy of histological diagnosis and the tissue acquisition rate of EUS-FNA by using the door-knocking method (DKM) with a standard 22-gauge needle.From November 2013 to August 2014, 82 patients who had solid pancreatic masses underwent EUS-FNA in which the conventional method (CM) and DKM with 2 respective passes in turn were used. The primary ...

Tópico(s): Pancreatitis Pathology and Treatment

2015 - Elsevier BV | Gastrointestinal Endoscopy

Artigo Revisado por pares

Junko Umeda, Takao Itoi, Takayoshi Tsuchiya, Atsushi Sofuni, Fumihide Itokawa, Kentaro Ishii, Shujiro Tsuji, Nobuhito Ikeuchi, Kentaro Kamada, Reina Tanaka, Ryosuke Tonozuka, Mitsuyoshi Honjo, Shuntaro Mukai, Mitsuru Fujita, Fuminori Moriyasu,

There are currently no dedicated plastic stents for EUS-guided hepaticogastrostomy (EUS-HGS).We prospectively evaluated the feasibility and the technical and functional success rates of our newly designed plastic stent for EUS-HGS.Prospective preliminary feasibility study.A tertiary-care referral center.Twenty-three consecutive patients were treated. The reasons for requiring EUS-HGS were periampullary tumor invasion (n=9), altered anatomy (n=7), failed duodenal intubation (n=3), and previous ERCP failure ( ...

Tópico(s): Esophageal and GI Pathology

2015 - Elsevier BV | Gastrointestinal Endoscopy