Produção Nacional
Revisado por pares
Camila C. Portugal, Thaísa Godinho da Encarnação, Renato Socodato, Sarah Rodrigues-Moreira, Dan Brudzewsky, António Francisco Ambrósio, Roberto Paes‐de‐Carvalho,
Ascorbate is an important antioxidant, which also displays important functions in neuronal tissues, including the retina. The retina is responsible for the initial steps of visual processing, which is further refined in cerebral high-order centers. The retina is also a prototypical model for studying physiologic aspects of cells that comprise the nervous system. Of major importance also is the cellular messenger nitric oxide (NO). Previous studies have demonstrated the significance of NO for both ...
Tópico(s): Vitamin D Research Studies
2011 - Elsevier BV | Journal of Biological Chemistry
Tópico(s): Bioeconomy and Sustainability Development
2022 - Elsevier BV | One Earth
Produção Nacional
Revisado por pares
Leandro Campos Pinto, Carlos Rogério de Mello, L. D. Norton, Sérgio Henrique Godinho Silva, Luís Renato Silva Taveira, Nilton Curi,
ABSTRACT In Brazil, the Mantiqueira Range, southeastern region, shelters the last remnants of the ecologically important Upper Montane Tropical Forest. since extensive exploration that has been taking place in this biome for decades, the influence of land-use changes on hydropedology in these areas must be investigated once major land-use changes have been observed. This study aims to evaluate the land-use influence on soil drainable porosity (SDP) in a headwater watershed located in the Mantiqueira ...
Tópico(s): Hydrology and Watershed Management Studies
2017 - UNIVERSIDADE FEDERAL DE LAVRAS | Ciência e Agrotecnologia
Produção Nacional
Revisado por pares
Lucas Vieira, João de Deus Godinho, Renato Adriane Alves Ruas, Vinícius Ribeiro Faria, Alberto Carvalho Filho,
... de glifosato LUCAS CAIXETA VIEIRA1, JOÃO DE DEUS GODINHO JUNIOR2, RENATO ADRIANE ALVES RUAS3, VINÍCIUS RIBEIRO FARIA4, ALBERTO CARVALHO ...
Tópico(s): Growth and nutrition in plants
2019 - | ENERGIA NA AGRICULTURA
Produção Nacional
Rigel Rego de Sá Godinho, Renato Hiroshi Salvioni Ueta, David Del Curto, Délio Eulálio Martins, Marcelo Wajchenberg, Eduardo Barros Puertas,
OBJETIVO: Analisar a mensuração manual do ângulo de Cobb entre profissionais com diferentes experiências da área de Ortopedia e Traumatologia e Cirurgia da Coluna Vertebral, para observar se existem diferenças na avaliação das radiografias de pacientes portadores de escoliose idiopática intra e interobservadores, a ponto de influenciar no tratamento e seguimento desses pacientes. MÉTODOS: Foram utilizadas para este estudo 22 radiografias simples da coluna toracolombar, póstero-anterior, de pacientes ...
Tópico(s): Spine and Intervertebral Disc Pathology
2011 - Sociedade Brasileira de Coluna (SBC) | Coluna/Columna
Produção Nacional
Marcelo A. Carvalho, Maria A. Pino, Rachel Karchin, Jennifer Beddor, Martha Godinho-Netto, Rafael D. Mesquita, Renato Santos Rodarte, Danielle Copello Vaz, Viviane A. Monteiro, Siranoush Manoukian, Mara Colombo, Carla B. Ripamonti, Richard Rosenquist, Graeme Suthers, Åke Borg, Paolo Radice, Scott Grist, Álvaro N.A. Monteiro, Blasé Billack,
Germline mutations that inactivate BRCA1 are responsible for breast and ovarian cancer susceptibility. One possible outcome of genetic testing for BRCA1 is the finding of a genetic variant of uncertain significance for which there is no information regarding its cancer association. This outcome leads to problems in risk assessment, counseling and preventive care. The purpose of the present study was to functionally evaluate seven unclassified variants of BRCA1 including a genomic deletion that leads ...
Tópico(s): Gene expression and cancer classification
2008 - Elsevier BV | Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
Produção Nacional
Revisado por pares
Eulália Sakano, Emanuel S.C. Sarinho, Álvaro A. Cruz, Antônio Carlos Pastorino, Edwin Tamashiro, Fábio Chigres Kuschnir, Fábio Fernandes Morato Castro, Fabrizio Ricci Romano, Gustavo Falbo Wandalsen, Herberto José Chong‐Neto, João Ferreira de Mello, Luciana Rodrígues Silva, M C Rizzo, Mônica A.M. Miyake, Nelson Augusto Rosário Filho, Norma de Paula Motta Rubini, Olavo Mion, Paulo Augusto Moreira Camargos, Renato Roithmann, Ricardo Godinho, Shirley Shizue Nagata Pignatari, Tânia Sih, Wilma Terezinha Anselmo‐Lima, Dirceu Solé,
The guidelines on allergic rhinitis aim to update knowledge about the disease and care for affected patients. The initiative called "Allergic Rhinitis and its Impact on Asthma", initially published in 2001 and updated in 2008 and 2010, has been very successful in disseminating information and evidence, as well as providing a classification of severity and proposing a systemized treatment protocol. In order to include the participation of other medical professionals in the treatment of allergic rhinitis, ...
Tópico(s): Food Allergy and Anaphylaxis Research
2017 - Elsevier BV | Brazilian Journal of Otorhinolaryngology
Muthiah Vaduganathan, Robert A. Harrington, Gregg W. Stone, Efthymios Deliargyris, Philippe Gabríel Steg, C. Michael Gibson, Christian W. Hamm, Matthew J. Price, Alberto Menozzi, Jayne Prats, Steven Elkin, Kenneth W. Mahaffey, Harvey D. White, Deepak L. Bhatt, Fernando Cura, M Ballarino, Aníbal Damonte, Diego Grinfeld, Carlos Alejandro Álvarez, Alberto Ocaña, A. Farshid, Brendan Gunalingam, Craig Jeurgens, Harry C. Lowe, H. Hallani, G. Nelson, Gishel New, Ronald Dick, Jeffrey Lefkovits, Stephen W. Duffy, Nick Bett, Raibhan Yadav, P. Garrahy, Ron Lehman, Philip E. Aylward, John D. Horowitz, M. Worthley, D. Cross, Jaime Rankin, Peter Thompson, Phil Roberts-Thomson, D. Cross, Rohan Jayasinghe, Con Aroney, Kurt Huber, F Leisch, Johann Altenberger, Georg Gaul, Thomas Neunteufl, Franz Weidinger, Herwig Schuchlenz, H. Wéber, Werner Benzer, Paulo Roberto Ferreira ROSSI, Breno Oliveira Almeida, Antônio Francisco Godinho, Fábio Vilas‐Boas, Luciano Janussi Vacanti, Renato Giestas Serpa, José Antonio Jatene, Gilmar Reis, Jamil Abdalla Saad, Marcos Maynar-Mariño, Roberto Botelho, Constantino Costantini, Ricardo Wang, Dalton Bertolim Précoma, M Rati, L. C. Bodanese, Euler Roberto Fernandes Manenti, João Paulo Zouvi, Rogério Tumelero, Arthur Herdy, Eulógio Martinez Filho, Antônio Carlos Carvalho, Roberto Alexandre Franken, Lawrence Title, Charles Lazzam, François Reeves, Tamaz Shaburishvili, Gulnara Chapidze, Merab Mamatsashvili, Irakli Khintibidze, Kurt Huber, Hans‐Georg Olbrich, Sabine Genth‐Zotz, S Moebius-Winkler, Michael Buerke, Stefan Hoffmann, Peter W. Radke, Helge Moellmann, Hugo A. Katus, HANS-FRIEDRICH VOEHRINGER, Christian Hengstenberg, Volker Klauß, Johannes Brachmann, Aftab Ahmad Khan, Sampath Kumar, P.P. Mohanan, Praveen Chandra, M. Bhaskar Rao, S. S. Ramesh, Keyur Parikh, Arun Srinivas, Nakul Sinha, G. K. Surya Prakash, Shirish Hiremath, Anil Mishra, Sanjeeb Roy, Kamal Sethi, Ashwani Mehta, Tejas Patel, Suman Bhandari, Milind Gadkari, Milind Gadkari, Stefano De Servi, Giuseppe Musumeci, Alberto Menozzi, Bernardo Cortese, Giancarlo Marenzi, Raffaele De Caterina, Ralph Stewart, Gerard Devlin, Scott A. Harding, John F. Elliott, Gerard T. Wilkins, D. Scott, Sławomir Dobrzycki, Waldemar Dorniak, Dariusz Dudek, Zbigniew Gąsior, Jarosław Hiczkiewicz, Zdzisława Kornacewicz‐Jach, Leszek Kubik, Krzysztof Kuc, Jerzy Kuźniar, Walentyna Mazurek, Jakub Ostrowski, Michał Tendera, Andrzej Wiśniewski, Elżbieta Zinka, Krzysztof Żmudka, Jana Pawła, Maciej Kośmider, Seweryna, Andrés Íñiguez, Rafael Melgares, Francisco Javier Goicolea, José Hernández, Javier Zueco, Igor Kraiz, Mykola Vatutin, Anatoliy Polyakov, Y.N. Sokolov, Kenneth W. House, Charles Campbell, Timothy Trageser, Kenneth W. Baran, Neal S. Kleiman, Roberto Medina, Roger Hill, M. Zubair Jafar, David Drenning, Herbert Ladley, Adil Al‐Nahhas, Alan Niederman, Amit Goyal, William B. Abernethy, Naseem Jaffrani, Richard Zelman, B J Negus, José Marquez, Ehtisham Mahmud, William J. French, John Paulowski, Charles V. Pollack, M Mines, Robert Federici, Marc J. Schweiger, Kalim Habet, Ofsman Quintana, Thomas W. Nygaard, Steve Orlow, Douglas Spriggs, Ivan Chavez, M. Warner, Richard Paulus, David Cochran, Cary Hirsch, Ajay Virmani, Peter Soukas, Nalin Srivastava, Laurent Ferrier, Annapoorna Kini, Mark A. Greenberg, Hartmut Herrmann, Valerian Fernandes, Barry Bertolet, Ron Waksman, Joseph B. Henderson, Harinder Gogia, Maged Amine, Kourosh Mastali, Thomas Stuckey, Peter Hui, Luigi Pacifico, Todd Caulfield, Wilson Ginete, William L. Ballard, Robert Iwaoka, Joseph Stella, Vijay K. Misra, Costa Andreou, Michele Voeltz, Wayne Batchelor, Cezar Staniloae, Sanford J. Gips, Jeffrey Kramer, Paul Mahoney, John Wang, Prospero Gogo, David G. Rizik, David G. Rizik, Rex J. Winters, G. Hunter Mackenzie, Stephen J. Jenkins, Paul Teirstein, Pierre P. Leimgruber, J. Christopher Scott, Seth Krauss, Steven Rohrbeck, Robert G. Martin, Gustavo Grieco, Louis Cannon, Don Westerhausen, F. David Fortuin, Steven P. Schulman, Joel Cohn, Brent McLaurin, Jorge Saucedo, Robert Wozniak, J. J. Hall, Kevin Marzo, Merrill Krolick, Lawrence W. Gimple, Eric Hockstad, Arsenio Rodriguez, John Kao, Adhir Shroff, Michael Attubato, Ramon Quesada, Ernesto Rivera, Larry S. Dean, Russell Raymond, Thomas M. Amidon, David Lee, Spencer King, John S. Douglas, Abnash C. Jain, J Patrick Kleaveland, Mitchell Driesman, Krishna Kumar, Glen J. Kowalchuk, Behzad Taghizadeh, Lawrence A. Barr, Keith Benzuly, Tarek Helmy, Duane S. Pinto, Joseph Aragon, Reginald Low, Phillip A. Horwitz, Thomas D. LeGalley, Dominick J. Angiolillo, Rajesh Sachdeva, Kenneth M. Kent, Luis Gruberg, Richard G. Bach, Thomas Pow, Charles O’Shaughnessy, Shing Chiu Wong, Saeed R. Shaikh, Arthur Reitman, Mark E. Lawrence, Fernando Cura, Alejandro García Escudero, Carlos Poy, Miguel Miceli, Antonio Pocoví, Hugo Londero, Jorge Baccaro, L. Z. Polonetsky, Aliaksey Karotkin, Leanid Shubau, Eduardo da Rosa Maffini, Bruno Martins Machado, José Airton,
Cangrelor, an intravenous, reversible P2Y12 antagonist, is approved for use in patients undergoing percutaneous coronary intervention (PCI). This study sought to evaluate the efficacy and safety of cangrelor compared with clopidogrel in subgroups that did and did not receive glycoprotein IIb/IIIa inhibitors (GPIs). This pooled, patient-level analysis of the 3 CHAMPION (Cangrelor versus Standard Therapy to Achieve Optimal Management of Platelet Inhibition) trials analyzed all randomized patients who ...
Elsevier BV
Produção Nacional
Marluce Rodrigues Godinho, Aldo Pacheco Ferreira, Vívian Assis Fayer, Renato José Bonfatti, Rosângela Maria Greco,
capacidade de trabalho", "capacidade para o trabalho", "avaliação da capacidade de trabalho", "desempenho do trabalho", "work capacity evaluation", "work capacity", "work ability" e "work ability index".
Tópico(s): Business and Management Studies
2017 - | Revista Brasileira de Medicina do Trabalho
Produção Nacional
Revisado por pares
Leandro Braga Godinho, Mario R. Moura, Renato Neves Feio,
We provide new records of Corythomantis greeningi from southeastern Brazil, extending its southernmost distribution. The new records of C. greeningi are from an area of the Cerrado biome, in the State of Minas Gerais.
Tópico(s): Wildlife-Road Interactions and Conservation
2013 - Pensoft Publishers | Check List
André M. C. Gomes, Guilherme B. Farias, Manuel Dias‐Silva, Joel Laia, Amelia Chiara Trombetta, Ana Godinho‐Santos, Pedro Rosmaninho, Diana F. Santos, Carolina M. Conceição, Renato Costa‐Reis, Maria Adão‐Serrano, Catarina Mota, Afonso R. M. Almeida, Ana E. Sousa, S. Fernandes,
Abstract Accelerate lung repair in SARS‐CoV‐2 pneumonia is essential for pandemic handling. Innate lymphoid cells (ILCs) are likely players, given their role in mucosal protection and tissue homeostasis. We studied ILC subpopulations at two time points in a cohort of patients admitted in the hospital due to SARS‐CoV‐2 infection. COVID‐19 patients with moderate/severe respiratory failure featured profound depletion of circulating ILCs at hospital admission, in agreement with overall lymphocyte depletion. ...
Tópico(s): COVID-19 Clinical Research Studies
2021 - Wiley | European Journal of Immunology
Produção Nacional
Revisado por pares
Carlos Alberto Maganha, Marcelo Augusto Fontenelle Ribeiro, Rosiane Mattar, Maurício Godinho, Renato Augusto Teixeira, E. Ferreira, Sara Toassa Gomes Solha, Fernanda Santos Grossi, Larissa Mariz de Oliveira Godinho,
The anatomical and physiological alterations of pregnancy interfere with the repercussions and the approach to trauma.
Tópico(s): Migration, Health and Trauma
2023 - Thieme Medical Publishers (Germany) | Revista Brasileira Ginecologia e Obstetrícia
Produção Nacional
Revisado por pares
Marco Antônio Peixoto, DANIELLEN MARTINS VIEIRA PIRES, Leandro Braga Godinho, Renato Neves Feio,
Proceratophrys carranca Godinho, Moura, Lacerda & Feio, 2013 belongs to the P. cristiceps group, which currently contains 15 species (Brandão et al. 2013). This group is defined by species lacking palpebral appendages, postocular swellings and inhabiting mainly seasonally dry open environments (Cerrado and Caatinga domains) in Brazil (Giaretta et al. 2000). Using molecular data, Amaro et al. (2009) showed the non-monophyletic status of the P. cristiceps group. These authors emphasize that more studies ...
Tópico(s): Wildlife-Road Interactions and Conservation
2014 - Q15088586 | Zootaxa
Produção Nacional
Revisado por pares
Lucas Padoan de Sá Godinho, Renato Paes de Almeida, André Marconato, Maurício G. M. Santos, Antônio Romalino Santos Fragoso-Cesar,
O Supergrupo Camaquã, localizado na região centro-sul do Rio Grande do Sul, Brasil, constitui uma bacia sedimentar pós-orogênica do tipo rift, cuja deposição ocorreu em ambiente continental entre o Ediacarano e o Eocambriano. O topo da sucessão do Supergrupo Camaquã é representado pelo Grupo Guaritas, uma unidade formada por depósitos fluviais, eólicos e de leques aluviais que abriga importantes registros da sedimentação logo após o final das orogêneses neoproterozoicas que deram origem ao supercontinente ...
Tópico(s): Geochemistry and Elemental Analysis
2013 - UNIVERSIDADE DE SÃO PAULO | Geologia USP Série Científica
Produção Nacional
Revisado por pares
Brunno Renato Farias Verçoza, Joseane Lima Prado Godinho, Sara Teixeira de Macedo-Silva, K. Huber, Franz Bracher, Wanderley de Souza, Juliany Cola Fernandes Rodrigues,
Treatment of leishmaniasis involves the use of antimonials, miltefosine, amphotericin B or pentamidine. However, the side effects of these drugs and the reports of drug-resistant parasites demonstrate the need for new treatments that are safer and more efficacious. Histone deacetylase inhibitors are a new class of compounds with potential to treat leishmaniasis. Herein, we evaluated the effects of KH-TFMDI, a novel histone deacetylase inhibitor, on Leishmania amazonensis promastigotes and intracellular ...
Tópico(s): Enzyme function and inhibition
2017 - Springer Science+Business Media | APOPTOSIS
Produção Nacional
Revisado por pares
Thaísa Godinho da Encarnação, Camila C. Portugal, Caio Eduardo Nogueira, Felipe N. Santiago, Renato Socodato, Roberto Paes‐de‐Carvalho,
Tópico(s): Alcoholism and Thiamine Deficiency
2018 - Springer Science+Business Media | Molecular Neurobiology
Produção Nacional
Revisado por pares
Andréa Mendonça Rodrigues, Cristian Roncada, Giovana dos Santos, João Paulo Heinzmann‐Filho, Rodrigo Godinho de Souza, Mauro Henrique Moraes Vargas, Leonardo Araújo Pinto, Marcus Herbert Jones, Renato T. Stein, Paulo Márcio Pitrez,
AbstractObjective: To describe the clinical characteristics, lung function, radiological findings, and the inflammatory cell profile in induced sputum in children and adolescents with severe therapy-resistant asthma (STRA) treated at a referral center in southern Brazil.Methods: We retrospectively analyzed children and adolescents (3-18 years of age) with uncontrolled STRA treated with high-dose inhaled corticosteroids and long-acting β2 agonists. We prospectively collected data on disease control, ...
Tópico(s): Inhalation and Respiratory Drug Delivery
2015 - Sociedade Brasileira de Pneumologia e Tisiologia | Jornal Brasileiro de Pneumologia
Isabel Marques, Paulo Almeida, Renato Alves, Maria João Dias, Ana Godinho, José B. Pereira‐Leal,
The interdisciplinary nature of bioinformatics makes it an ideal framework to develop activities enabling enquiry-based learning. We describe here the development and implementation of a pilot project to use bioinformatics-based research activities in high schools, called “Bioinformatics@school.” It includes web-based research projects that students can pursue alone or under teacher supervision and a teacher training program. The project is organized so as to enable discussion of key results between ...
Tópico(s): Biomedical and Engineering Education
2014 - Public Library of Science | PLoS Computational Biology
Produção Nacional
Revisado por pares
Maurício G. M. Santos, Renato Paes de Almeida, Lucas P. S. Godinho, André Marconato, Nigel P. Mountney,
Abstract Process‐based and facies models to account for the origin of pre‐vegetation (i.e. pre‐Silurian) preserved fluvial sedimentary architectures remain poorly defined in terms of their ability to account for the nature of the fluvial conditions required to accumulate and preserve architectural elements in the absence of the stabilizing influence of vegetation. In pre‐vegetation fluvial successions, the repeated reworking of bars and minor channels that resulted in the generation and preservation ...
Tópico(s): Hydrology and Sediment Transport Processes
2013 - Wiley | Sedimentology
Produção Nacional
Revisado por pares
João de Deus Godinho, Lucas Vieira, Renato Adriane Alves Ruas, Alberto Carvalho Filho, Vinícius Ribeiro Faria, Pedro Ivo Vieira Good God,
Background: The study of the interactions between equipment, application methods, and spray mixtures is fundamental to optimize the application of pesticides. The determination of the best combination of these factors can reduce the drift during the application of the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D). Objective: The objective this paper is to study the influence of nozzle models, working pressures, and surfactant adjuvant in reducing the drift of 2,4-D. Methods: The spectrum of nozzle ...
Tópico(s): Seed Germination and Physiology
2020 - Sociedade Brasileira da Ciência das Plantas Daninhas | Planta Daninha
Produção Nacional
Revisado por pares
Betânia Peixoto, Letícia Godinho de Souza, Renato Sérgio de Lima,
Este artigo objetiva entender a vitimização em São Paulo, ao longo do tempo. Utilizamos como referencial teórico os modelos sistêmicos da dinâmica criminal. Foram utilizadas duas pesquisas realizadas pelo Insper nos anos de 2003 e 2008. Investigamos as mudanças e os fatores correlacionados, de acordo com o tipo de crime: roubo a pessoa, furto a pessoa, roubo e furto a residência, roubo e furto de veículo e agressão física. Foram considerados fatores referentes a três níveis: atributos dos respondentes, ...
Tópico(s): Traffic and Road Safety
2014 - Escola Nacional de Administracao Publica | Revista do Serviço Público
Produção Nacional
Revisado por pares
Ana Paula Duarte de Souza, Lidiane Alves de Azeredo Leitão, Fernanda Luisi, Rodrigo Godinho de Souza, Sandra Eugênia Coutinho, Jaqueline Ramos da Silva, Rita Mattiello, Paulo Márcio Pitrez, Renato T. Stein, Leonardo Araújo Pinto,
ABSTRACT Objective: To investigate the correlation between respiratory syncytial viral load and length of hospitalization in infants with acute wheezing episodes. Methods: This was a two-year, cross-sectional study of infants ≤ 12 months of age with bronchiolitis at the time of admission to a tertiary hospital. For the identification of respiratory viruses, nasopharyngeal secretions were collected. Samples were analyzed (throughout the study period) by direct immunofluorescence and (in the second year ...
Tópico(s): Tracheal and airway disorders
2016 - Sociedade Brasileira de Pneumologia e Tisiologia | Jornal Brasileiro de Pneumologia
Gonçalo Godinho, Carolina Madeira, Ana Grangeia, Pedro Cardoso, Renato Silva, Elisete Brandão, Ângela Carneiro, Fernando Falcão‐Reis, Sérgio Estrela‐Silva,
Background To characterize the phenotype and genotype of a syndrome associating posterior microphthalmos (PM), retinitis pigmentosa (RP), foveoschisis, and foveal hypoplasia (FH) in a consanguineous Portuguese family.Materials and methods Three siblings were studied and underwent comprehensive eye examinations for best-corrected visual acuity, axial length, refractive error, B-mode ultrasound, electroretinography, retinography, fluorescein angiography (FA), kinetic visual field (VF), and optical coherence ...
Tópico(s): Retinal Development and Disorders
2020 - Taylor & Francis | Ophthalmic Genetics
Produção Nacional
Daniele Lima da Costa, Misael Freitas dos Santos, Talita Godinho Bezerra, Renato Bezerra da Silva Ribeiro, João Ricardo Vasconcellos Gama, Lia Oliveira Melo, Lucas Cunha Ximenes, Amanda Alves Coelho,
Objetivou-se analisar a estrutura e distribuicao espacial da especie S. globulifera em uma floresta de varzea baixa, estado do Para, inferindo sobre a possibilidade de seu manejo madeireiro. Foram instaladas, sistematicamente, 25 unidades amostrais de 20 m x 250 m e mensuradas todas as arvores de S. globulifera com diâmetro a altura do peito (DAP) ≥ 15 cm. Para analise da regeneracao foi instalada subparcela de 10 m x 10 m em cada unidade de amostra e inventariadas as arvores pela contagem em cinco ...
Tópico(s): Soil Management and Crop Yield
2018 - UNIVERSIDADE FEDERAL DE MATO GROSSO | Advances in Forestry Science
Produção Nacional
Revisado por pares
Camila C. Portugal, Thaísa Godinho da Encarnação, Ivan Domith, Alexandre dos Santos‐Rodrigues, Nádia Almeida de Oliveira, Renato Socodato, Roberto Paes‐de‐Carvalho,
Ascorbate, the reduced form of Vitamin C, is one of the most abundant and important low–molecular weight antioxidants in living tissues. Most animals synthesize vitamin C, but some primates, including humans, have lost this capacity due to disruption in L-gulono-gamma-lactone oxidase gene. Because of this incapacity, those animals must obtain Vitamin C from the diet. Ascorbate is highly concentrated in the central nervous system (CNS), including the retina, and plays essential roles in neuronal physiology. ...
Tópico(s): Anesthesia and Neurotoxicity Research
2019 - Frontiers Media | Frontiers in Neuroscience
Produção Nacional
Revisado por pares
Lucas Padoan de Sá Godinho, Renato Paes de Almeida, Maurício G. M. Santos, André Marconato, Antônio Romalino Santos Fragoso-Cesar,
The Guaritas Group (Cambrian, RS, Southern Brazil) encompasses sedimentary deposits of bedload or mixed load rivers, eolian dune fields and alluvial fans, and constitutes a rare sedimentary record of Cambrian age in Eastern South America. In this context, its uppermost unit, named Serra do Apertado Formation, contains the last record of stabilization phase of the Gondwana Continent in south and southeastern Brazil. Nevertheless, there are no published detailed studies on its facies and depositional ...
Tópico(s): Paleontology and Stratigraphy of Fossils
2013 - UNIVERSIDADE DE SÃO PAULO | Geologia USP Série Científica
... Vanesa Arzamendia, Josué A. Azevedo, Fausto E. Barbo, Renato S. Bérnils, Bruna E. Bolochio, Marcio Borges-Martins, Marcela Brasil-Godinho, Henrique Braz, Marcus A. Buononato, Diego F. Cisneros- ...
Tópico(s): Wildlife Ecology and Conservation
1894 - University of Chicago Press | The American Naturalist
Produção Nacional
Revisado por pares
César Augusto Diniz Xavier, Márcio Tadeu Godinho, Talita Bernardon Mar, Camila Geovana Ferro, Osvaldo F. L. Sande, José Cleydson F. Silva, Roberto Ramos‐Sobrinho, Renato Nascimento, Iraíldes Pereira Assunção, Gaus Silvestre de Andrade Lima, Alison T. M. Lima, F. Murilo Zerbini,
Abstract Several key evolutionary events marked the evolution of geminiviruses, culminating with the emergence of divided (bipartite) genomes represented by viruses classified in the genus Begomovirus . This genus represents the most abundant group of multipartite viruses, contributing significantly to the observed abundance of multipartite species in the virosphere. Although aspects related to virus‐host interactions and evolutionary dynamics have been extensively studied, the bipartite nature of ...
Tópico(s): Viral Infections and Vectors
2021 - Wiley | Molecular Ecology
Produção Nacional
Revisado por pares
Paulo Márcio Pitrez, Rodrigo Godinho de Souza, Cristian Roncada, João Paulo Heinzmann‐Filho, Giovana dos Santos, Leonardo Araújo Pinto, Marcus Herbert Jones, Renato T. Stein,
Severe asthma in children is a global health problem. Severe therapy-resistant asthma (STRA) in children is a major clinical challenge due to persistent symptoms despite high doses of corticosteroids and results in high public health costs. Omalizumab (anti-IgE monoclonal antibody) has been described as an effective add-on therapy in these patients. The characteristics of children with STRA from low- and middle-income countries have scarcely been reported, and no real-life study has been published ...
Tópico(s): Inhalation and Respiratory Drug Delivery
2017 - Wiley | Pediatric Pulmonology
Produção Nacional
Revisado por pares
Renato Tavares dos Santos Pereira, Catarina S. Porto, Rosely Oliveira Godinho, Fernando Maurício Francis Abdalla,
The aim of the present study was to investigate the effects of estrogen lack and estrogen replacement on the production of total [3H]inositol phosphate ([3H]IP) induced by the activation of muscarinic acetylcholine receptors (mAChRs) and on the mechanisms for inactivation of acetylcholine. Hippocampi were obtained from rats in proestrus (PE), ovariectomized for 15 days (C15), ovariectomized for 15 days and then treated with 17β-estradiol for 7 days (E7) and ovariectomized and immediately treated with 17β- ...
Tópico(s): Cholinesterase and Neurodegenerative Diseases
2008 - Elsevier BV | Biochemical Pharmacology