Michael J. Schwartz, Huixian Liu, David H. Hwang, Hideki Kawamoto, Douglas S. Scherr,
... In vitro experiments were carried out using mouse (RENCA) and human (CAKI-1, CAKI-2, and A- ... cell viability in vitro. For in vivo experiments, RENCA cells were injected into the tail vein of ... was expressed in all cell lines tested, with RENCA cells showing the highest level of expression. Imidazoquinolines inhibited in vitro cell viability of RENCA, CAKI-2, and A-498 cell lines in ... not inhibited significantly. Apoptosis induction was pronounced in RENCA cells treated with imidazoquinoline. Compared with placebo, oral ...
Tópico(s): Synthesis and Biological Evaluation
2009 - Elsevier BV | Urology
Naoko Seki, Alan D. Brooks, Clive R.D. Carter, Timothy Back, Erin M. Parsoneault, Mark J. Smyth, Robert H. Wiltrout, Thomas J. Sayers,
... achieved some limited success. The murine renal cancer Renca has been used as a model for developing ... been completely identified. After successful biological therapy of Renca in BALB/c mice, we generated CTLs in ... α, and Fas ligand (FasL) in response to Renca. CTL used both granule- and FasL-mediated mechanisms to lyse Renca, although granule-mediated killing was the predominant lytic ... γ and TNF-α increased the sensitivity of Renca cells to CTL lysis by both granule- and ... mediated death pathways. Adoptive transfer of these anti-Renca CTL into tumor-bearing mice cured most mice ...
Tópico(s): Immunotherapy and Immune Responses
2002 - American Association of Immunologists | The Journal of Immunology
Shigetaka Kudo, Ryuichiro Konda, Wataru Obara, Daisuke Kudo, Kenzaburo Tani, Yusuke Nakamura, Tomoaki Fujioka,
... to a mouse renal cell carcinoma cell line (Renca). Female BALB/c mice were inoculated subcutaneously with wild-type Renca (Renca/Wild) cells or Renca cells transfected with the BAI-1 (Renca/BAI-1) or LacZ (Renca/LacZ) gene. Tumor growth was observed every other ... 11 to 31 days after implantation of the Renca/Wild or Renca/BAI1 tumor. Tumor blood flow was measured by ... by enzyme-linked immunoassay. The size of the Renca/BAI1 tumor was significantly (p<0.01) suppressed compared to the Renca/Wild and Renca/LacZ tumors 21 days after ...
Tópico(s): Angiogenesis and VEGF in Cancer
2007 - Elsevier BV | Oncology Reports
Masafumi Kumano, Isao Hara, Junya Furukawa, Shuntaro Oniki, Hiroshi Nagai, Hideaki Miyake, Masato Fujisawa,
... effects of IL-21 gene transfer into mouse RenCa renal cell carcinoma cells, so that cells could ... effect.The IL-21 gene was introduced into RenCa cells by the liposome mediated method using Lipofectamine. ... in vivo antitumor effect of IL-21 secreting RenCa cells was assessed by subcutaneous injection into syngeneic ... splenocytes in mice injected with IL-21 secreting RenCa cells was determined using the CytoTox 96 nonradioactive ... vaccine study was also performed.IL-21 secreting RenCa cells were almost all rejected following subcutaneous injection ...
Tópico(s): Immunotherapy and Immune Responses
2007 - Lippincott Williams & Wilkins | The Journal of Urology
Oleg Shvarts, Nicolette Janzen, John S. Lam, John T. Leppert, Randy Caliliw, Robert A. Figlin, Arie S. Belldegrun, Gang Zeng,
... was used to transduce the murine RCC line, RENCA. In vivo growth kinetics and CA-IX expression were compared between RENCA and RENCA/CA-IX using heterotopic, metastatic, and orthotopic models.Transduction of RENCA created the RENCA/CA-IX line with nearly 100% CA-IX ... number of metastases was noted after inoculation of RENCA and RENCA/CA-IX. In the orthotopic model, autopsy revealed ... lymph nodes. In all the above models, the RENCA/CA-IX tumors retained expression of CA-IX, as demonstrated by immunohistochemistry staining.RENCA/CA-IX is the first tumor model that ...
Tópico(s): Cholinesterase and Neurodegenerative Diseases
2006 - Elsevier BV | Urology
Tetsuo Ogushi, Satoru Takahashi, Takumi Takeuchi, Tomohiko Urano, Kuniko Horie‐Inoue, Jinpei Kumagai, Tadaichi Kitamura, Yasuyoshi Ouchi, Masami Muramatsu, Satoshi Inoue,
... c. implantation of murine renal cell carcinoma (RCC) Renca cells. Overexpression of EBAG9 did not promote the proliferation of culture Renca cells; however, the inoculated Renca cells harboring EBAG9 (Renca-EBAG9) in BALB/c mice grew faster and developed larger tumors compared with Renca cells expressing vector alone (Renca-vector). After renal subcapsular implantation, Renca-EBAG9 tumors significantly enlarged compared with Renca-vector tumors in BALB/c mice, whereas both Renca-EBAG9 and Renca-vector tumors were developed with ...
Tópico(s): Epigenetics and DNA Methylation
2005 - American Association for Cancer Research | Cancer Research
Yoshihisa Kinoshita, Takuro Kono, R Yasumoto, Taketoshi Kishimoto, Ching Y. Wang, Gabriel P. Haas, Nobuyasu Nishisaka,
... efficacy of vaccination with murine renal cell carcinoma (Renca) secreting the granulocyte-macrophage colony-stimulating factor (GM- ... 6 (IL-6) gene for the treatment of Renca tumor. Murine GM-CSF and murine IL-6 genes were introduced and expressed in Renca cells (Renca-GM-CSF and Renca-IL-6). For a prevaccination study, wild-type Renca cells were injected subcutaneously into Balb/c mice ... been vaccinated three times with inactivated wild-type Renca, Renca-GM-CSF, Renca-IL-6, or a mixture of Renca-GM-CSF and Renca-IL-6 cells 7, ...
Tópico(s): vaccines and immunoinformatics approaches
2001 - Lippincott Williams & Wilkins | Journal of Immunotherapy
Shilajit Kundu, Isaac Yi Kim, David J. Zelner, Lynn Janulis, Shannon Goodwin, Jason D. Engel, CHUNG LEE,
... PATTERN IN A MURINE RENAL CARCINOMA CELL LINE, RENCA SHILAJIT D. KUNDU, ISAAC Y. KIM, DAVID ZELNER, ... in an aggressive murine renal carcinoma cell line, Renca, investigated in a series of experiments. The growth of Renca cells, in tissue culture, was not sensitive to ... inducing the expression of plasminogen activator inhibitor-I. Renca cells expressed TGF-beta 1 mRNA and protein, ... The level of TGF-beta 1 production by Renca cells was moderate, thus eliminating the possibility that ... masking the effect of TGF-beta sensitivity. Furthermore, Renca cells expressed T beta R-I mRNA, but ...
Tópico(s): Renal and related cancers
1998 - Lippincott Williams & Wilkins | The Journal of Urology
Nobuyasu Nishisaka, Atul Maini, Yoshihisa Kinoshita, R Yasumoto, Taketoshi Kishimoto, Richard F. Jones, Philo Morse, Gilda G. Hillman, Ching Y. Wang, Gabriel P. Haas,
... colony-stimulating factor (GM-CSF) using the mouse Renca pulmonary metastasis model. Wild-type Renca (W/Renca) were transfected with pEF-BOS vector incorporating cDNAs ... or GM-CSF to express these cytokines. W/Renca, IL-2-producing Renca (Renca/IL-2), and IFN-γ-producing Renca (Renca/IFN-γ) produced subcutaneous tumor at the injection ... tumors were found in the GM-CSF-producing Renca (Renca/GM-CSF) group (zero of eight). Renca/IFN- ...
Tópico(s): Cancer Research and Treatments
1999 - Lippincott Williams & Wilkins | Journal of Immunotherapy
Prithy C. Martis, Atira Dudley, Melissa A. Bemrose, Hunter L. Gazda, Blair H. Smith, Lawrence S. Gazda,
Agarose encapsulated murine renal adenocarcinoma cells (RENCA macrobeads) are currently being investigated in clinical trials as a treatment for therapy-resistant metastatic colorectal cancer. We have previously demonstrated the capacity of RENCA macrobeads to produce diffusible substances that markedly inhibit ... observed inhibition in targeted tumor cells exposed to RENCA macrobeads.We evaluated changes in transcription factor responses, ... cellular receptors in targeted tumor cells exposed to RENCA macrobeads.Factors secreted by RENCA macrobeads significantly up- ...
Tópico(s): Cancer-related Molecular Pathways
2018 - BioMed Central | BMC Cancer
Takuto Hara, Hideaki Miyake, Nobuyuki Hinata, Masato Fujisawa,
... and sensitivity to sunitinib in the mouse RCC RenCa model.We established RenCa/sh-PD-L1 by transfecting RenCa cells with a plasmid carrying a short hairpin ... targeted against PD-L1. The growth pattern of RenCa/sh-PD-L1 with or without sunitinib was compared to that of RenCa cells transfected with control plasmid alone (RenCa/Co).No significant difference in growth or sensitivity to sinitinib was noted between RenCa/sh-PD-L1 and RenCa/Co cells in vitro. The tumor volume in mice subcutaneously injected with RenCa/sh-PD-L1 was significantly smaller than that ...
Tópico(s): Cancer Genomics and Diagnostics
2019 - International Institute of Anticancer Research (IIAR) Conferences 1997. Athens, Greece. Abstracts | Anticancer Research
Anil Shanker, Ari D. Brooks, Carlos A Tristan, John W. Wine, Peter J. Elliott, Hideo Yagita∥, Kazuyoshi Takeda, Mark J. Smyth, William J. Murphy, T. J. Sayers,
... monoclonal antibody, in mouse carcinomas. METHODS; Mice bearing Renca-FLAG (renal) or 4T1 (mammary) tumors were treated ... or MD5-1 and examined for lung metastases (Renca-FLAG: n = 93; 4T1: n = 40) or monitored for survival (Renca-FLAG: n = 143). Toxicity was assessed by histopathology and hematology. Viability and apoptotic signaling in Renca-FLAG and 4T1 cells treated with bortezomib alone ... tests were two-sided.Bortezomib (20 nM) sensitized Renca-FLAG and 4T1 cells to TRAIL-mediated apoptosis ( ... numbers of viable cells, bortezomib + TRAIL vs TRAIL: Renca-FLAG, 95% vs 34%, difference = 61%, 95% confidence ...
Tópico(s): Hepatitis B Virus Studies
2008 - Oxford University Press | JNCI Journal of the National Cancer Institute
Hea Young Oh, Soo Mee Kwon, Sun Il Kim, Yang Won Jae, Sung Joon Hong,
... of ZD1839 in a murine renal cell carcinoma (RENCA) model. <i>Materials and Methods:</i> The effect of ZD1839 on the cellular proliferation of RENCA cells in vitro was measured by colorimetric assay. For the in vivo studies, RENCA cells were adsorbed in Gelfoam and implanted into ... analysis was performed to observe EGFR expression in RENCA cells and tumor tissues. Microvessel density (MVD) was ... i> ZD1839 showed a dose-dependent inhibition of RENCA cellular proliferation. ZD1839 treatment resulted in a marked ...
Tópico(s): Renal cell carcinoma treatment
2005 - Karger Publishers | Urologia Internationalis
T. Morita, Naoyuki Shinohara, Akihiko Tokue,
... of fumagillin (TNP-470), on murine renal carcinoma (Renca) in vivo and in vitro.The effect of TNP-470 on the growth of Renca cells in vitro was measured by angiogenesis assay ... counting with dye exclusion. In the angiogenesis assay, Renca cells were injected intradermally and the number of ... the subcutaneous tumour growth and lung metastasis of Renca, Renca cells were injected subcutaneously or intravenously in BALB/ ... of TNP-470 inhibited the angiogenesis induced by Renca in a dose-dependent manner. In the subcutaneous ...
Tópico(s): Renal cell carcinoma treatment
1994 - Wiley | British Journal of Urology
Isao Hara, Hak Hotta, Noriyuki Sato, Hiroshi Eto, Soichi Arakawa, Sadao Kamidono,
... IL-2) gene into mouse renal cell carcinoma (RenCa) in order to examine the mechanism of tumor rejection. IL-2 gene-transfected RenCa (RenCa/IL-2Hi) exhibited marked retardation of tumor growth ... implanted in a syngeneic host. Growth retardation of RenCa/IL-2Hi was also observed in athymic nude ... with anti-asialo GM1 antibody. Histological analysis of RenCa/IL-2Hi tumors disclosed non-specific inflammatory changes ... hosts. Co-injection of Bacillus Calmette Guerin with RenCa/IL-2Hi considerably enhanced the anti-tumor effects. ...
Tópico(s): CAR-T cell therapy research
1996 - Oxford University Press | Japanese Journal of Cancer Research
Hiroaki Nishimatsu, Takumi Takeuchi, Tetsuo Ueki, Takahiro Kajiwara, Nobuo Moriyama, Toshimitsu Ishida, Baoxing Li, Tadao Kakizoe, Tadaichi Kitamura,
... responses. In this system, two murine CD95L-transfected renca clones and a control renca clone transfected only with the vector were implanted ... c nude mice. Both CD95L-expressing and control renca clones formed macroscopic tumors in all of the ... implantation. Growth of tumors of murine CD95L-transfected renca cells was significantly better than that of control renca cells in Balb/c mice, while the growth ... CD95L-expressing or control tumors. CD95L expressed on renca cells possibly suppressed immune responses against renca tumors ...
Tópico(s): Toxin Mechanisms and Immunotoxins
1999 - Springer Science+Business Media | Cancer Immunology Immunotherapy
Jason D. Engel, Shilajit Kundu, T.Y. Yang, Sharon Lang, Shannon Goodwin, Lynn Janulis, Jin Seon Cho, Jay Chang, Seong‐Jin Kim, Chung Lee,
... tumorigenicity in an aggressive murine renal carcinoma line, Renca. These cells do not express TβR-II. Because ... ability to restore tumor suppressor activity in the Renca cell line with its introduction would elucidate the ... TβR-II as a tumor suppressor gene. Methods. Renca cells were stably transfected with a retrovirus-mediated ... TβR-II transfected cells was tested. Wild-type Renca cells and cells transfected with the control vector ... Expression of TβR-II mRNA was evident in Renca cells after transfection with the TβR-II construct. ...
Tópico(s): Pancreatic and Hepatic Oncology Research
1999 - Elsevier BV | Urology
Keke Fan, Ming Zhou, Manas K. Pathak, Daniel J. Lindner, Cengiz Z. Altuntas, Vincent K. Tuohy, Ernest C. Borden, Taolin Yi,
... were investigated in a murine renal cancer model (Renca). Despite its failure to inhibit Renca cell proliferation in cultures, SSG induced 61% growth inhibition of Renca tumors in BALB/c mice coincident with an ... deficient mice. T cell involvement in the anti-Renca tumor action of the combination was suggested by ... in BALB/c mice, but failed to inhibit Renca tumor growth in athymic nude mice and that ... the mice. These results together demonstrate an anti-Renca tumor activity of SSG that was enhanced in ...
Tópico(s): Galectins and Cancer Biology
2005 - American Association of Immunologists | The Journal of Immunology
Qiang Zhang, Jonathan N. Rubenstein, Victoria C. Liu, Irwin Park, Thomas L. Jang, Chung Lee,
The murine renal cell carcinoma (Renca) cells are insensitive to TGF-beta due to a lack of TGF-beta type II receptor (TbetaR-II). The objective of ... this loss of sensitivity to TGF-beta in Renca cells. Renca cells were cultured and treated with 5-Aza- ... blot analysis before and after the treatment of Renca cells with 5-Aza. The expression of phosphorylated ... in the conditioned medium were measured by ELISA. Renca cells did not express TbetaR-II prior to ... Results of the present study indicated that, in Renca cells, the loss of sensitivity to TGF-beta ...
Tópico(s): Renal and related cancers
2004 - Elsevier BV | Life Sciences
Thomas J. Sayers, Alan D. Brooks, Jong‐Keuk Lee, Robert G. Fenton, Kristin L. Komschlies, Jon M. Wigginton, Robin Winkler-Pickett, Robert H. Wiltrout,
Abstract Mice bearing the experimental murine renal cancer Renca can be successfully treated with some forms of ... used by NK and T cells to lyse Renca cells. Renca cells normally express low levels of Fas that ... FasL). Lysis via Fas occurs by apoptosis, since Renca shows all the typical characteristics of apoptosis. No ... the granule-mediated pathway predominated in killing of Renca by activated NK cells, while the Fas/FasL pathway contributed significantly to cell-mediated killing of Renca by activated T cells. These results suggest that ...
Tópico(s): T-cell and B-cell Immunology
1998 - American Association of Immunologists | The Journal of Immunology
Kent T. Perry, Larry Wong, Victoria Liu, Irwin Park, Qiang Zhang, Varun Rejen, Xuemei Huang, Norm D. Smith, Borko Jovanovic, Scott Lonning, Beverly A. Teicher, Chung Lee,
The mouse renal cell carcinoma line, Renca, is insensitive to transforming growth factor-beta (TGF-beta) in vitro. The present study was conducted to determine whether removal of TGF- ... beta antibody into mice receiving intravenous injection of Renca tumor cells or infection of TGF-beta antisense ... grew almost as well as did the unmodified Renca cells, suggesting that the host's immune system ... antitumor role.These results indicate that progression of Renca tumor can be inhibited by eliminating TGF-beta ...
Tópico(s): Kruppel-like factors research
2008 - Elsevier BV | Urology
Christina Perske, Nitza Lahat, Sharon Sheffy Levin, Haim Bitterman, Bernhard Hemmerlein, Michal A. Rahat,
... that the mouse renal cell carcinoma cell line, RENCA, which, on stimulation, expresses high levels of iNOS ... by the microRNA miR-146a, as inhibition of RENCA cells with anti-miR- 146a restores iNOS expression ... in uninhibited cells, P < 0.001). In vivo, RENCA tumor cells do not stain for iNOS, while ... expressed iNOS mRNA. Restoring iNOS protein expression in RENCA cells using anti-miR-146a increases macrophage-induced death of RENCA cells by 73% (P < 0.01) in vitro ...
Tópico(s): Cancer-related molecular mechanisms research
2010 - Elsevier BV | American Journal Of Pathology
Akio Horiguchi, Makoto Sumitomo, Junichi Asakuma, Takako Asano, Tomohiko Asano, Masamichi Hayakawa,
... properties were examined in murine renal cancer cell Renca. The changes in cell cycle-associated proteins, p21( ... efficacy of fluvastatin to murine pulmonary metastasis of Renca was examined.Fluvastatin inhibited in vitro growth of Renca cells in a time- and dose-dependent manner, ... Waf1/Cip1) and p53. The invasive properties of Renca cells through Matrigel were inhibited by fluvastatin, with ... kg/d, for 12 days after inoculation of Renca cells via the tail vein, significantly decreased the ... vitro tumor growth, invasion, angiogenesis, and metastasis of Renca cells, oral administration of fluvastatin could be a ...
Tópico(s): Lipoproteins and Cardiovascular Health
2004 - American Association for Cancer Research | Clinical Cancer Research
Thomas J. Sayers, Alan D. Brooks, Naoko Seki, Mark J. Smyth, Hideo Yagita∥, Bruce R. Blazar, Anatoli Malyguine,
... Activated T cells lyse the murine renal cancer Renca. We have examined the mechanism of tumor cell ... 6 and BALB/c T cells can lyse Renca cells through the use of both granule- and ... Pfp-/- T cells use FasL. The lysis of Renca by Pfp-/- T cells is only partially inhibited ... that caspase-independent signaling is also important for Renca cell lysis. When the reactive oxygen scavenger butylated ... combination with ZVAD-FMK a substantial reduction of Renca lysis was observed. Therefore, the caspase-independent generation ...
Tópico(s): Immunotherapy and Immune Responses
2000 - Oxford University Press | Journal of Leukocyte Biology
Samim Ali, Robert C. Rees, Dayna Anderson, Malcolm Reed, J R Goepel, Nicola J. Brown,
RENCA-IL-2 (Murine Renal Cell Carcinoma transfected with murine IL-2 gene) cells were rejected by ... c mice, which developed ‘immunity’ to subsequent parental RENCA tumour cell challenge. Splenocytes adoptively transferred this immunity. ... that enables visualization of events within the microvasculature. RENCA cells were implanted into the mouse cremaster muscle ... from naive and ‘immune’ animals, into both the RENCA tumour and the surrounding normal cremaster muscle microcirculation ... of naive mice or mice previously immunized with RENCA-IL-2 were injected systemically into tumour-bearer ...
Tópico(s): Cancer Immunotherapy and Biomarkers
2000 - Springer Nature | British Journal of Cancer
Jong‐Keuk Lee, Thomas J. Sayers, Alan D. Brooks, Timothy Back, Howard A. Young, Kristin L. Komschlies, Jon M. Wigginton, Robert H. Wiltrout,
... solid tumor growth was investigated. Murine renal carcinoma (Renca) cells were constitutively resistant to Fas-mediated killing ... after exposure to IFN-gamma and TNF. Transfected Renca cells overexpressing Fas were efficiently killed in vitro ... to anti-Fas Ab (Jo2). When Fas-overexpressing Renca cells were injected into syngenic BALB/c mice, ... and prolonged survival that was not observed for Renca cells that overexpressed a truncated nonfunctional Fas receptor. ... cells and in vivo apoptosis in Fas-overexpressing Renca tumors, and Fas-overexpressing Renca cells were also ...
Tópico(s): Cancer-related Molecular Pathways
2000 - American Association of Immunologists | The Journal of Immunology
Shoji Hara, Hiroshi Nagai, Hideaki Miyake, Kazuki Yamanaka, Soichi Arakawa, Masamitsu Ichihashi, Sadao Kamidono, Isao Hara,
... original IL-18 cDNA was transduced into the RenCa mouse renal cell carcinoma cell line. Expression of ... immunodeficient mice were challenged with IL-18 secreting RenCa cells. Results: Although the modified and original IL-18 genes transduced RenCa showed almost the same level of IL-18 messenger RNA expression, only RenCa cells transduced with modified IL-18 gene secreted ... antitumor effect. Moreover, the modified IL-18 transduced RenCa induced tumor vaccine effect against parental RenCa cells injected at a distant site. Conclusions: Immune ...
Tópico(s): T-cell and B-cell Immunology
2001 - Lippincott Williams & Wilkins | The Journal of Urology
Gamal-Andre Banat, Oliver Christ, B. Cochlovius, H. Pralle, Margot Zöller,
... for immunotherapy of cancer. We recently noted that RENCA cells effectively interfere with the in vivo activation of RENCA-specific T cells. To unravel the underlying mechanism, we evaluated the influence of RENCA cells on a mixed-lymphocyte/ tumour reaction as ... an allogeneic mixed-lymphocyte reaction. We observed that RENCA cells were not directly immunosuppressive. Instead, they initiated ... Expression of the costimulatory molecule B7.1 by RENCA cells prevented induction of anergy, while expression of ...
Tópico(s): Cancer Immunotherapy and Biomarkers
2001 - Springer Science+Business Media | Cancer Immunology Immunotherapy
Stefano Pierini, Chongyun Fang, Stavros Rafail, John G. Facciponte, Jialing Huang, Francesco De Sanctis, Mark A. Morgan, Mireia Uribe‐Herranz, János L. Tanyi, Andrea Facciabene,
... immunotherapy. In this article, we show that the RENCA tumor cell line harbors TAMAs that can drive ... pulsing dendritic cells with enriched mitochondrial proteins from RENCA cells. Our dendritic cell-based RENCA mitochondrial lysate vaccine elicited a cytotoxic T cell ... vivo and conferred durable protection against challenge with RENCA cells when used in a prophylactic or therapeutic setting. By sequencing mtDNA from RENCA cells, we identified two mutated molecules: COX1 and ... not from ND5 had therapeutic properties similar to RENCA mitochondrial protein preparation. Thus, TAMAs can elicit effective ...
Tópico(s): Cancer Immunotherapy and Biomarkers
2015 - American Association of Immunologists | The Journal of Immunology
Qi Xu, Sanna Junttila, Andreas Scherer, Khem Raj Giri, Oona Kivelä, Ilya Skovorodkin, Juha Röning, Susan E. Quaggin, Hans‐Peter Marti, Jingdong Shan, Anatoly Samoylenko, Seppo Vainio,
... Itgb2 gene expression was achieved in mouse RCC (Renca) cells. The live-cell imaging analysis revealed inhibition ... migration and cell viability in the gene-KD Renca cells in comparison to Renca controls. Upon siRNA treatment, the transwell invasion capacity of Renca cells was also inhibited. Finally, we mixed E11.5 MM with yellow fluorescent protein (YFP)-expressing Renca cells to establish chimera organoids. Strikingly, we found that the Bnip3-, Cav1- and Gsn-KD Renca-YFP+ cells as a chimera with the MM ...
Tópico(s): Renal cell carcinoma treatment
2017 - The Company of Biologists | Disease Models & Mechanisms