Teuku Muhammad Haykal Putra, Renan Sukmawan, Elen Elen, Celly Anantaria Atmadikoesoemah, Dwita Rian Desandri, Manoefris Kasim,
Myocardial fibrosis in rheumatic mitral stenosis (MS) is caused by chronic inflammatory process. Its occurrence may lead to hemodynamic problems, especially after cardiac surgery. Myocardial fibrosis predicts worse morbidity after cardiac surgery, notably in coronary heart disease and aortic valve abnormalities. However, this issue has not been explored yet among patients with rheumatic MS. The aim of the study was to investigate prognostic impact of myocardial fibrosis to postoperative morbidity ...
Tópico(s): Infective Endocarditis Diagnosis and Management
2019 - Thieme Medical Publishers (Germany) | International Journal of Angiology
Teuku Muhammad Haykal Putra, Renan Sukmawan, Dwita Rian Desandri, Celly Anantaria Atmadikoesoemah, Elen Elen, Manoefris Kasim,
Background: Patients with rheumatic mitral stenosis (MS) experience changes in left ventricular (LV) dimensions after mitral valve surgery. We sought to investigate changes in LV dimensional parameters after mitral valve surgery and find out whether the same changes occurred in different extents of myocardial fibrosis. Methods: This prospective observational study comprised 43 patients with rheumatic MS planned for mitral valve surgery between October 2017 and April 2018 in National Cardiovascular ...
Tópico(s): Cardiac Arrhythmias and Treatments
2020 - Tehran University of Medical Sciences | The Journal of Tehran University Heart Center
Dwita Rian Desandri, T R Witarsa, Renan Sukmawan,
Abstract Funding Acknowledgements Type of funding sources: None. Background Phaleria macrocarpa fruit extract was reported in decreasing the low-density lipoprotein cholesterol (LDL-C) level as well as increasing the high-density lipoprotein cholesterol (HDL-C) level in animal studies. Currently, proprotein convertase subtilisin/kexin type 9 (PCSK-9) has become a novel target for lipid modification, as it enhances the degradation of LDL-C receptors in hepatocytes. However, the effect of Phaleria macrocarpa ...
Tópico(s): Inflammatory mediators and NSAID effects
2023 - Oxford University Press | European Journal of Preventive Cardiology