Guillaume Richard‐Carpentier, Amy E. DeZern, Koichi Takahashi, Marina Konopleva, Sanam Loghavi, Lucia Masárová, Yesid Alvarado, Farhad Ravandi, Guillermo Montalban‐Bravo, Kiran Naqvi, Koji Sasaki, Ricardo Delumpa, Monica Kwari, Mikkael A. Sekeres, Aziz Nazha, Gail J. Roboz, Hagop M. Kantarjian, Guillermo Garcia‐Manero, Courtney D. DiNardo,
Background: Isocitrate dehydrogenase 2 (IDH2) mutations occur in 5-10% of patients (pts) with myelodysplastic syndrome (MDS) and are frequently associated with intermediate-risk cytogenetics, excess bone marrow blasts, neutropenia and sustained platelets. Enasidenib (ENA) is a selective oral inhibitor of the mutant IDH2 enzyme with single-agent activity in relapsed/refractory acute myeloid leukemia (AML). This study was designed to evaluate the efficacy and tolerability of ENA alone and in combination ...
Tópico(s): Lung Cancer Treatments and Mutations
2019 - Elsevier BV | Blood
Sai Prasad Desikan, Farhad Ravandi, Naveen Pemmaraju, Marina Konopleva, Sanam Loghavi, Elias Jabbour, Naval Daver, Nitin Jain, Kelly S. Chien, Abhishek Maiti, Guillermo Montalban‐Bravo, Tapan M. Kadia, Walid Macaron, Ricardo Delumpa, Monica Kwari, Gautam Borthakur, Nicholas J. Short,
Introduction: RAS pathway mutations are common mechanisms of resistance to acute myeloid leukemia (AML) therapies. Trametinib, an oral MEK inhibitor, has been shown to have single-agent activity in relapsed/refractory AML and preclinical synergy with venetoclax. Methods: We conducted a single-center, open-label, phase 2 trial of the combination of azacitidine, venetoclax, and trametinib in patients with relapsed or refractory AML harboring a RAS pathway-activating mutation. Results: Sixteen patients ...
Tópico(s): Protein Degradation and Inhibitors
2022 - Karger Publishers | Acta Haematologica
Nicholas J. Short, Courtney D. DiNardo, Naval Daver, Daniel Nguyen, Musa Yılmaz, Tapan M. Kadia, Guillermo Garcia‐Manero, Ghayas C. Issa, Xuelin Huang, Wei Qiao, Koji Sasaki, Guillermo Montalban‐Bravo, Kelly S. Chien, Gautam Borthakur, Ricardo Delumpa, Anna Milton, Sherry Pierce, Elias Jabbour, Marina Konopleva, Hagop M. Kantarjian, Farhad Ravandi,
Abstract Background: Gilteritinib improves response rates and overall survival (OS) compared with chemotherapy in patients (pts) with relapsed/refractory (R/R) FLT3-mutated acute myeloid leukemia (AML). For older pts with newly diagnosed (ND) FLT3-mutated AML who are unfit for intensive chemotherapy, azacitidine plus venetoclax is the current standard of care, although remission durations are relatively short, largely due to FLT3-driven relapses. We therefore sought to evaluate the triplet regimen of ...
Tópico(s): Chronic Lymphocytic Leukemia Research
2021 - Elsevier BV | Blood
Produção Nacional
Revisado por pares
Gabriele Ina Graf, Daniel Hastreiter, Luiz Everson da Silva, Ricardo Andrade Rebelo, Antonio Montalbán, Alexander McKillop,
Tópico(s): Chemical Reactions and Mechanisms
2002 - Elsevier BV | Tetrahedron
Sangeetha Venugopal, Courtney D. DiNardo, Koichi Takahashi, Marina Konopleva, Sanam Loghavi, Gautam Borthakur, Amy E. DeZern, Lucia Masárová, Naval Daver, Nicholas J. Short, Yesid Alvarado, Farhad Ravandi, Guillermo Montalban‐Bravo, Koji Sasaki, Ricardo Delumpa, Mikkael A. Sekeres, Bhumika J. Patel, Gail J. Roboz, Hagop M. Kantarjian, Guillermo Garcia‐Manero,
7010 Background: Isocitrate dehydrogenase 2 ( IDH2) mutations occur in 5% of patients (pts) with MDS. Enasidenib (ENA) is a selective oral inhibitor of the mutant IDH2 enzyme with single-agent activity in relapsed/refractory acute myeloid leukemia (AML). We report the results of the open label phase II study designed to evaluate the efficacy and tolerability of ENA, as monotherapy or in combination with azacitidine (AZA) in pts with higher-risk IDH2-mutated MDS (NCT03383575). Methods: Pts with higher-risk [ ...
Tópico(s): Lung Cancer Treatments and Mutations
2021 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
José Manuel Caperos Montalbán, Ricardo Olmos, Antonio Pardo,
Abstract. Correlation analysis is one of the most widely used methods to test hypotheses in social and health sciences; however, its use is not completely error free. We have explored the frequency of inconsistencies between reported p-values and the associated test statistics in 186 papers published in four Spanish journals of psychology (1,950 correlation tests); we have also collected information about the use of one- versus two-tailed tests in the presence of directional hypotheses, and about ...
Tópico(s): Meta-analysis and systematic reviews
2016 - | Methodology
Produção Nacional
Revisado por pares
... ao movimento de ruptura com o Hospital Dia Ricardo Montalban, representado pelo modelo psiquiátrico hospitalocêntrico medicalizador, para a ... research approached from the rupture movement with the Ricardo Montalban Day Hospital which is represented by the psychiatric ...
Tópico(s): Youth, Drugs, and Violence
2019 - UNIVERSIDADE DO ESTADO DO RIO DE JANEIRO | Revista Em Pauta
Produção Nacional
Revisado por pares
Carolina S. Silva, Maria Fernanda Pimentel, Ricardo S. Honorato, Célio Pasquini, J.M. Prats-Montalbán, Alberto Ferrer,
Hyperspectral images in the near infrared range (HSI-NIR) were evaluated as a nondestructive method to detect fraud in documents. Three different types of typical forgeries were simulated by (a) obliterating text, (b) adding text and (c) approaching the crossing lines problem. The simulated samples were imaged in the range of 928-2524 nm with spectral and spatial resolutions of 6.3 nm and 10 μm, respectively. After data pre-processing, different chemometric techniques were evaluated for each type of ...
Tópico(s): Currency Recognition and Detection
2014 - Royal Society of Chemistry | The Analyst
Robert Goertsches, Pablo Villoslada, Manuel Comabella, Xavier Montalbán, Arcadi Navarro, Emilio G. de la Concha, Rafael Arroyo, Adolfo López de Munaín, David Otaegui, Ricardo Palácios, Jordi Pérez‐Tur, Áslaug Jónasdóttir, Kjartan Benediktsson, Ragnheiður Fossdal, Stephen Sawcer, Efrosini Setakis, Alastair Compston,
Abstract In order to identify the genomic regions that might confer susceptibility to multiple sclerosis (MS) in the Spanish population, we have performed a genome-wide screen for association in patients with MS using pooled DNA from 200 clinical cases and 200 healthy controls. The pools were typed using 5546 microsatellites. The typing was repeated for the most promising 1269 markers after which 191 potentially associated markers were identified. Eleven of these markers map to the MHC region, and 14 to ...
Tópico(s): T-cell and B-cell Immunology
2003 - Elsevier BV | Journal of Neuroimmunology
Clara Matute‐Blanch, Laura Calvo‐Barreiro, Iria Carballo‐Carbajal, Ricardo Gonzalo, Álex Sánchez‐Pla, Miquel Vila, Xavier Montalbán, Manuel Comabella,
Abstract Chitinase 3-like 1 (CHI3L1) is known to play a role as prognostic biomarker in the early stages of multiple sclerosis (MS), and patients with high cerebrospinal fluid CHI3L1 levels have an increased risk for the development of neurological disability. Here, we investigated its potential neurotoxic effect by adding recombinant CHI3L1 in vitro to primary cultures of mouse cortical neurons and evaluating both neuronal functionality and survival by immunofluorescence. CHI3L1 induced a significant ...
Tópico(s): Parasites and Host Interactions
2020 - Nature Portfolio | Scientific Reports
Marta G. Fuster, Mercedes G. Montalbán, Guzmán Carissimi, Beatriz Lima, Gabriela E. Feresin, Manuel Cano, Juan J. Giner‐Casares, J. J. López Cascales, Ricardo D. Enriz, Gloria Víllora,
Pathogenic bacteria have the ability to develop antibiotic resistance mechanisms. Their action consists mainly in the production of bacterial enzymes that inactivate antibiotics or the appearance of modifications that prevent the arrival of the drug at the target point or the alteration of the target point itself, becoming a growing problem for health systems. Chitosan–gold nanoparticles (Cs-AuNPs) have been shown as effective bactericidal materials avoiding damage to human cells. In this work, Cs- ...
Tópico(s): Antimicrobial agents and applications
2020 - Multidisciplinary Digital Publishing Institute | Nanomaterials
Juan J. Lahuerta-Palacios, Maria Del Pilar Garcia Valdes, José J. Navas‐Palacios, María Ángeles Montalbán, Santiago Larregla, Guillermo Martín–Núñez, Francisco J. Fernández-Debora, Ricardo Ruiz De Adana,
The clinical features and diagnostic evaluation of six patients affected by prolymphocytic leukemia (PLL), are described. Some of the cases deviate from a relatively uniform and aggressive clinical course of the disease entity. An actuarial survival analysis of 60 cases gathered from the literature and the authors' experience indicate that the cases showing the most prolongated evolution may reach 30% of the total. The different aggressiveness in the clinical course of these patients does not depend ...
Tópico(s): Acute Myeloid Leukemia Research
1985 - Wiley | Cancer
... estrellas, a Yvonne De Carlo, Vittorio Gasmann y Ricardo Montalbán. Las obras que recoge esta antología se adentran ...
Tópico(s): Latin American and Latino Studies
2008 - Department of Spanish and Portuguese, University of Kansas | Latin American theatre review
Nicholas J. Short, Courtney D. DiNardo, Naval Daver, Walid Macaron, Musa Yılmaz, Gautam Borthakur, Guillermo Montalban‐Bravo, Guillermo Garcia‐Manero, Ghayas C. Issa, Koji Sasaki, Philip A. Thompson, Jan A. Burger, Abhishek Maiti, Yesid Alvarado, Monica Kwari, Ricardo Delumpa, Jennifer Thankachan, Ejiroghene Mayor, Christopher Loiselle, Anna Milton, Glenda Banks, Tapan M. Kadia, Marina Konopleva, Hagop M. Kantarjian, Farhad Ravandi,
Tópico(s): Chronic Lymphocytic Leukemia Research
2022 - Elsevier BV | Blood
Carlos Montalbán, Víctor Abraira, Luca Arcaini, Eva Domingo‐Domènech, Pablo Guisado‐Vasco, Emilio Iannitto, Manuela Mollejo, Estella Matutes, Andrés J.M. Ferreri, Antonio Salar, Sara Rattotti, Andrea Carpaneto, Ricardo Pérez, José-Luis Bello, Miguel‐Teodoro Hernández, Dolores Caballero, Félix Carbonell, Miguel Á. Piris,
Splenic marginal zone lymphoma (SMZL) is a well- established type of indolent B-cell lymphoma [1] that usually involves the bone marrow, peripheral blood and spleen, and only rarely presents with n...
Tópico(s): Viral-associated cancers and disorders
2013 - Taylor & Francis | Leukemia & lymphoma/Leukemia and lymphoma
Carlos Montalbán, Víctor Abraira, Luca Arcaini, Eva Domingo‐Domènech, Pablo Guisado‐Vasco, Emilio Iannito, Manuela Mollejo, Estella Matutes, Andrés J.M. Ferreri, Antonio Salar, Sara Rattotti, Andrea Carpaneto, Ricardo Pérez Fernández, José Belló, Miguel‐Teodoro Hernández, Dolores Caballero, Félix Carbonell, Miguel Á. Piris,
Summary This international retrospective study of 593 S plenic M arginal Z one L ymphoma ( SMZL ) patients aimed to identify factors that determine treatment initiation and influence lymphoma‐specific survival ( LSS ). Logistic regression was used to identify the factors associated with treatment. A Cox regression was used to analyse LSS in a derivation cohort of 366 patients. This produced a prognostic index ( PI ) and enabled the identification of three risk groups. The resulting stratification was validated ...
Tópico(s): Viral-associated cancers and disorders
2012 - Wiley | British Journal of Haematology
Nicholas J. Short, Muharrem Müftüoǧlu, Faustine Ong, Lewis Nasr, Walid Macaron, Guillermo Montalban‐Bravo, Yesid Alvarado, Mahesh Basyal, Naval Daver, Courtney D. DiNardo, Gautam Borthakur, Nitin Jain, Maro Ohanian, Elias Jabbour, Ghayas C. Issa, Wei Qiao, Xuelin Huang, Rashmi Kanagal‐Shamanna, Keyur P. Patel, Prithviraj Bose, Farhad Ravandi, Ricardo Delumpa, Regina Abramova, Guillermo Garcia‐Manero, Michael Andreeff, Jorge E. Cortés, Hagop M. Kantarjian,
Abstract Background Pevonedistat is a first-in-class, small molecular inhibitor of NEDD8-activating enzyme that has clinical activity in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). Preclinical data suggest synergy of pevonedistat with azacitidine and venetoclax. Methods This single-center, phase 1/2 study evaluated the combination of azacitidine, venetoclax and pevonedistat in older adults with newly diagnosed secondary AML or with MDS or chronic myelomonocytic leukemia (CMML) ...
Tópico(s): Protein Degradation and Inhibitors
2023 - BioMed Central | Journal of Hematology & Oncology
Elias Jabbour, Nicholas J. Short, Nitin Jain, Xuelin Huang, Guillermo Montalban‐Bravo, Pinaki P. Banerjee, Katayoun Rezvani, Xianli Jiang, Kun Hee Kim, Rashmi Kanagal‐Shamanna, Joseph D. Khoury, Keyur P. Patel, Tapan M. Kadia, Naval Daver, Kelly S. Chien, Yesid Alvarado, Guillermo Garcia‐Manero, Ghayas C. Issa, Fadi G. Haddad, Monica Kwari, Jennifer Thankachan, Ricardo Delumpa, Walid Macaron, Rebecca Garris, Marina Konopleva, Farhad Ravandi, Hagop M. Kantarjian,
Ponatinib and blinatumomab are effective therapies in patients with Philadelphia chromosome-positive (Ph-positive) acute lymphoblastic leukaemia, and their combination might be a promising treatment option. In this study, we aimed to evaluate this chemotherapy-free strategy.We did a single-centre, single-arm, phase 2 study at the University of Texas MD Anderson Cancer Center, Houston, TX, USA, in patients aged 18 years or older with newly diagnosed or relapsed or refractory Ph-positive acute lymphoblastic ...
Tópico(s): Chronic Lymphocytic Leukemia Research
2022 - Elsevier BV | The Lancet Haematology
David H. Miller, Robert J. Fox, J. Theodore Phillips, Michael Hutchinson, Eva Havrdová, Mariko Kita, Claudia A. M. Gandini Wheeler‐Kingshott, Daniel J. Tozer, David MacManus, Tarek Yousry, Mary Goodsell, Minhua Yang, Ray Zhang, Vissia Viglietta, Katherine Dawson, Robert J. Fox, J. Theodore Phillips, Michael Hutchinson, Eva Havrdová, Mariko Kita, Kate Wilson, Minhua Yang, Katherine Dawson, Jack P. Antel, James S. Ware, Chris H. Polman, Peter R. Kowey, Raymond Chung, George L. Bakris, John R. Richert, Burt Seibert, David Brandes, David Brassat, Bruce A. Cohen, Ricarda Diem, Myla Goldman, Robert Herndon, Aaron Miller, Hayrettin Tumani, Teresa Alfaro-Vidal, Carolina Lage Crespo, Jo Foster, K.R. Hunter, Almudena Garcia-Gomez, David MacManus, David Miller, Virginia Santana, Dan Tozer, Claudia A. M. Gandini Wheeler‐Kingshott, Tarek Yousry, Christopher Kneebone, Aliaksandr Fedulau, С А Лихачев, Elena Mikhailova, Halina Naumova, D. Decoo, Luc Vande Gaer, Christian Sindic, Sanja Grgić, Osman Sinanović, Enra Suljić, Надежда Делева, Dimitar Georgiev, Lyubomir Haralanov, Sonyia Ivanova, I Manchev, Dimitar Minchev, P. Stamenova, Ivailo Tournev, Elena Vacheva, Zahari Zahariev, Amit Bar-Or, Gregg Blevins, Marcelo Kremenchutzky, Felix Veloso, Norbert Witt, Roberto Vargas Howell, Alexander Parajeles Vindas, Mario Habek, Josip Rudež, Silva Soldo-Butković, Ranka Baraba Vurdelja, David Doležil, Eva Havrdová, Jiří Nova'k, Daniel Václavík, Katrin Antsov, Katrin Gross‐Paju, Sulev Haldre, Alla Palu, Toomas Toomsoo, Abdullatif Al Khedr, William Camu, Marc Debouverie, Gilles Defer, de Sèze, Pierre Labauge, Thibault Moreau, Jean Pelletier, L. Rumbach, Vera Daskalovska, Klemens Angnstwurm, Heike Beneš, Achim Berthele, H. J. BOLDT, Angelika Christopher, Tobias Derfuß, Ilonka Eisensehr, Peter Emrich, Wolfgang Feneberg, Frank Hoffmann, Reinhard Hohlfeld, Reinhard Hüntemann, Boris-Alexander Kallmann, Bernd C. Kieseier, Harald Landefeld, W. Lüer, Sabine Masri, Gereon Nelles, Patrick Oschmann, Christine Paschen, Gerd Reifschneider, Michael Sailer, Sebastian Schimrigk, Mechthild Spiegel-Meixensberger, B. Storch–Hagenlocher, Björn Tackenberg, Klaus Tiel‐Wilck, Clementine Karageorgiou, Panagiotis Papathanasopoulos, T. Thomaides, Nicholas Vlaikidis, Deepak Arjundas, Madhuri Behari, Amitabha Ghosh, Pahari Ghosh, Nasli R. Ichaporia, Dheeraj Khurana, Rahul Kulkarni, Suresh Kumar, Man Mohan Mehndiratta, Neeta Abhay Mehta, U. K. Misra, Joy Dev Mukherji, Shankara Nellikunja, Abdul Salem, Prahlad K. Sethi, Shalin Shah, Gagandeep Singh, Maneesh Kumar Singh, Yash Pal Singh, Rangasetty Srinivasa, Krishnan Vijayan, Michael Hutchinson, Bernard Sweeney, Ronit Gilad, Radi Shahien, Anita Paegle, César Delgado, Juan Escamilla, Bruno Estañol, Minerva Lopez, Miguel Ángel Macías-Rodríguez, G Punzo, Sandra Quiñones, Mariela Renteria, J.E.P. Santos, Mihail Gavriliuc, Stanislav Groppa, Olesea Odainic, Paul Timmings, Anna Członkowska, Małgorzata Dorobek, Wiesław Drozdowski, Waldemar Fryze, Hanka Hertmanowska, Anna Kamińska, Magdalena Kapelusiak-Pielok, Magdalena Kleczkowska, Jan Kochanowicz, Jacek Losy, Przemysław Nowacki, Walenty M. Nyka, Krystyna Pierzchała, Ryszard Podemski, Andrzej Potemkowski, Krzysztof Selmaj, Zbigniew Stelmasiak, Andrzej Szczudlik, Andrzej Tutaj, A Wajgt, Tomasz Zieliński, Rodica Bălașa, Valentin Ionescu-Dimancea, P. Mihancea, Cristian D. Popescu, Liviu Codrut Protosevici, Svetlana Miletić Drakulić, Čongor Nadj, R Raicević, Slobodan Vojinović, Edita Kahancová, Egon Kurča, L Lisý, Peter Turčáni, Rafael Arroyo, Óscar Fernández Fernández, Cristina Ramírez Guijarro, Guillermo Izquierdo, Fernando Sánchez López, Xavier Montalbán, Celia Oreja‐Guevara, José M. Prieto, Nataliya Buchakchyys'ka, Galyna Chmyr, Alla Goloborodko, Tetyana Kobys, Grygory Kushnir, V. Lebedynets, N. V. Lytvynenko, Sergii Moskovko, Tetyana Nehrych, Borys І. Palamar, Igor Pasyura, Т. I. Ryabichenko, Nataliya Voloshina, Michelle Apperson, Angela Applebee, Stephen W. Asher, Ricardo Ayala, Donald Ayres, S. Ausim Azizi, Matthew Baker, Brendan Bauer, Roberto Bomprezzi, Richard Buckler, Walter G. Carlini, Ángel Chinea, Stanley Cohan, Giles Crowell, Keith Edwards, G Eubank, Warren L. Felton, Patricia Fodor, John F. Foley, Corey Ford, Edward A. Fox, Robert J. Fox, Mary Forester, Steven Freedman, George P Garmany, Suzanne Gazda, Daniel Giang, Braeme Glaun, Scott Gold, Malcolm Gottesman, Mark Gudesblatt, Joseph Herbert, A Herskowitz, William Honeycutt, John Huddlestone, Richard Hull, Samuel F. Hunter, George J. Hutton, Dina Jacobs, Mark Janicki, Bhupendra Khatri, Revere P. Kinkel, Mariko Kita, Stanley Krolczyk, Lauren Krupp, Christopher LaGanke, Michael Levin, Jonathan Licht, Christopher Luzzio, Sharon Lynch, David H. Mattson, Daniel D. Mikol, Tamara Miller, Alireza Minagar, Galen W. Mitchell, Harold L. Moses, Donald Negroski, Stephen L. Newman, Gabriel Pardo, Malti Patel, Allan Perel, Joseph M. Phillips, Mary Ann Picone, Kottil Rammohan, T. Hemanth Rao, John R. Rinker, Saud Sadiq, John Schaeffer, William Sheremata, Robert K. Shin,
Objective: To evaluate the effects of oral delayed-release dimethyl fumarate (DMF; also known as gastro-resistant DMF) on MRI lesion activity and load, atrophy, and magnetization transfer ratio (MTR) measures from the Comparator and an Oral Fumarate in Relapsing-Remitting Multiple Sclerosis (CONFIRM) study. Methods: CONFIRM was a 2-year, placebo-controlled study of the efficacy and safety of DMF 240 mg twice (BID) or 3 times daily (TID) in 1,417 patients with relapsing-remitting multiple sclerosis (RRMS); subcutaneous ...
Lippincott Williams & Wilkins
... sus miembros se encuentran escritores como Manuel Vázquez Montalbán, Juan Marsé, Terenci Moix, Pere Gimferrer, Félix de Azúa, Luis Goytisolo y Jaime Gil de Biedma; críticos y editores como Josep Maria Castellet, Jorge Herralde, Esther Tusquets y Beatriz de Moura; arquitectos como Ricardo Bofill y Oriol Bohigas; además de fotógrafos, directores ...
Tópico(s): Media, Journalism, and Communication History
2013 - American Association of Teachers of Spanish and Portuguese | Hispania
Nicholas J. Short, Hagop M. Kantarjian, Marina Konopleva, Guillermo Montalban‐Bravo, Farhad Ravandi, Nitin Jain, Tapan M. Kadia, Yesid Alvarado Valero, Kelly S. Chien, Naval Daver, Walid Macaron, Koji Sasaki, Jennifer Thankachan, Ricardo Delumpa, Ejiroghene Mayor, Wuliamatu Deen, Christopher Loiselle, Monica Kwari, Rebecca Garris, Elias Jabbour,
7009 Background: Ponatinib and blinatumomab are highly active in Ph+ ALL. A chemotherapy-free combination of these agents may lead to durable remissions and reduce the need for stem cell transplant (SCT) in first remission. Methods: In this phase II study, adults with newly diagnosed (ND) Ph+ ALL, relapsed/refractory (R/R) Ph+ ALL, or CML in lymphoid blast phase (CML-LBP) received up to 5 cycles of blinatumomab. Ponatinib 30mg daily was given during cycle 1 and decreased to 15mg daily once a complete ...
Tópico(s): Chronic Lymphocytic Leukemia Research
2022 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
Andrea Sánchez Franco, Omar Abdel-Lah Fernández, Enrique Moro Alaejos, Beatriz Faus Díez, Susana María Martín Domínguez, Sonsoles Garrosa-Muñoz, Juan Manuel Nieto Arranz, Beatriz Barón-Salvador, Isaac Tapiador López, Andrea Eduardo Valera Montiel, Manuel José Torres Jurado, Antón Sánchez Lobo, J. Parra, Lourdes Hernández‐Cosido, Ricardo Vazquez Perfecto, Pedro Antonio Montalban Valverde, Felipe Carlos Parreño Manchado,
Abstract Iatrogenic Esophageal Disease post obesity treatment: severe esophageal dilatation related to adjustable gastric banding (AGB) Introduction Obesity is considered one of the biggest epidemics of the 21st century, which pushes us as health professionals to seek for solutions to this pathology. Within the medical-surgical approach, the most used techniques are gastric bypass, vertical gastrectomy and adjustable gastric banding (AGB). Even though they are frequently used, they are not free of ...
Tópico(s): Nutritional Studies and Diet
2024 - Oxford University Press | Diseases of the Esophagus
Sangeetha Venugopal, Courtney D. DiNardo, Koichi Takahashi, Marina Konopleva, Sanam Loghavi, Gautam Borthakur, Amy E. DeZern, Lucia Masárová, Naval Daver, Nicholas J. Short, Yesid Alvarado, Farhad Ravandi, Guillermo Montalban‐Bravo, Koji Sasaki, Ricardo Delumpa, Mikkael A. Sekeres, Bhumika J. Patel, Gail J. Roboz, Hagop M. Kantarjian, Guillermo Garcia‐Manero,
Tópico(s): Myeloproliferative Neoplasms: Diagnosis and Treatment
2021 - Elsevier BV | Clinical Lymphoma Myeloma & Leukemia
Sangeetha Venugopal, Courtney D. DiNardo, Koichi Takahashi, Marina Konopleva, Sanam Loghavi, Gautam Borthakur, Amy E. DeZern, Lucia Masárová, Naval Daver, Nicholas J. Short, Yesid Alvarado, Farhad Ravandi, Guillermo Montalban‐Bravo, Koji Sasaki, Ricardo Delumpa, Mikkael A. Sekeres, Bhumika J. Patel, Gail J. Roboz, Hagop M. Kantarjian, Guillermo Garcia‐Manero,
Context: Isocitrate dehydrogenase 2 (IDH2) mutations occur in 5% of patients (pts) with MDS. Enasidenib (ENA) is a selective oral mutant-IDH2 inhibitor with single-agent activity in relapsed/refractory AML. Objective: To evaluate the efficacy and tolerability of ENA, as monotherapy or in combination with azacitidine (AZA), in pts with higher-risk IDH2-mutated MDS (NCT03383575). Design and Setting: Multi-institutional, open-label, two-arm, non-randomized, phase II study. Patients and Interventions: Pts ...
Tópico(s): Multiple Myeloma Research and Treatments
2021 - Elsevier BV | Clinical Lymphoma Myeloma & Leukemia
René Carvajal, David Guananga-Álvarez, Carmen Tur, Juliana Esperalba, Marta Rodríguez‐Barranco, Ariadna Rando‐Segura, Blanca Borrás-Bermejo, Álvaro Cobo‐Calvo, Pere Carbonell‐Mirabent, Ricardo Zules-Oña, José Ángel Rodrigo‐Pendás, Xavier Martínez‐Gómez, Xavier Montalbán, Mar Tintoré, Susana Otero‐Romero,
Hepatitis B vaccination (HBV) requires 6 months to complete and is recommended for patients with multiple sclerosis (PWMS), particularly those who are candidates for anti-CD20 therapy. However, limited data exist on HBV immunogenicity in PWMS receiving disease-modifying therapies (DMTs) and the impact of starting anti-CD20 therapy during immunization. We aimed to evaluate HBV immunogenicity in PWMS starting anti-CD20 therapy during vaccination, focusing on the number of doses received before anti-CD20 ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2025 - Lippincott Williams & Wilkins | Neurology
Jonathan S. Chávez-Íñiguez, Melina Amador-Jimenez, José Manuel Montalbán-Castellanos, Fabiola Morraz-Mejia, Ricardo Rubio-Reynoso, Xochitl Ortiz-Macias, Guillermo García-García,
Tópico(s): Body Composition Measurement Techniques
2018 - Oxford University Press | Nephrology Dialysis Transplantation
Nicholas J. Short, Hagop M. Kantarjian, Nitin Jain, Xuelin Huang, Guillermo Montalban‐Bravo, Tapan M. Kadia, Naval Daver, Kelly S. Chien, Yesid Alvarado, Guillermo Garcia‐Manero, Ghayas C. Issa, Walid Macaron, Fadi G. Haddad, Monica Kwari, Ricardo Delumpa, Ejiroghene Mayor, Wuliamatu Deen, Jennifer Thankachan, Christopher Loiselle, Juan J. Rivera, Anna Milton, Lourdes Waller, Glenda Banks, Rebecca Garris, Marina Konopleva, Farhad Ravandi, Elias Jabbour,
Background: Ponatinib and blinatumomab both have single-agent activity in Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL). The combination of these two active agents could be an effective chemotherapy-free strategy for patients (pts) with Ph+ ALL and may reduce the need for allogeneic stem cell transplantation (SCT) in first remission. Methods: In this phase II study, pts ≥18 years of age with newly diagnosed Ph+ ALL were eligible. Pts who had received 1-2 previous cycles of ...
Tópico(s): Chronic Myeloid Leukemia Treatments
2022 - Elsevier BV | Blood
Robert J. Fox, Andrew Chan, Ralf Gold, J. Theodore Phillips, Krzysztof Selmaj, Ih Chang, Mark Novas, Jitesh Rana, Jing L. Marantz, Zdeněk Ambler, Edvard Ehler, Eva Havrdová, Eva Meluzínová, Ivan Rektor, Radomír Taláb, Ralf Gold, Hans‐Peter Hartung, Attila Csányi, László Csiba, Gábor Jakab, Rogier Q. Hintzen, Chris H. Polman, Wiesław Drozdowski, Waldemar Fryze, Jan Kochanowicz, Hubert Kwieciński, Zdzislaw Maciejek, Sebastian Schimrigk, Krzysztof Selmaj, Andrzej Szczudlik, A Wajgt, Anna Belova, A. Boiko, Alexander Elchaninov, Kozlov Va, Odinak Mm, С Б Шварков, A A Skoromets, I D Stolyarov, O. V. Vorobieva, И. А. Завалишин, Jan Hillert, Tomas Olsson, Ludwig Kappos, Mefküre Eraksoy, Rana Karabudak, Aksel Sıva, Gavin Giovannoni, Clive Hawkins, Mohammed Sharief, Basil Sharrack, Christian Confavreux, John E. Ware, Michael Barnett, Mark Paine, Jeannette Lechner‐Scott, Roy G. Beran, Caron Chapman, Raymond Schwartz, Helmut Butzkueven, Reynolds F Casse, Richard Macdonell, Thomas Berger, Franz Fazekas, Gerhard Ransmayr, K. Vass, Shibeshih Belachew, Peter Paul De Deyn, D. Decoo, Bénédicte Dubois, Robert Medaer, Pierrette Seeldrayers, Christian Sindic, Luc Vande Gaer, Ludo Vanopdenbosch, Sanja Grgić, Amit Bar‐Or, Virender Bhan, Jean‐Pierre Bouchard, Suzanne Christie, Pierre Grammond, François Jacques, Felix Veloso, Galina Vorobeychik, Vesna Brinar, Vida Demarin, Josip Rudež, Silva Soldo-Butković, Ranka Baraba Vurdelja, Zdeněk Ambler, David Doležil, Eva Havrdová, Petr Kaňovský, Eva Meluzínová, Jiří Nova'k, Ivan Rektor, Ondřej Škoda, Marta Vachová Duchcovská, William Camu, Pierre Clavelou Antoanela, Irène Coman, Christian Confavreux, Gilles Edan, Olivier Gout, Christine Lebrun‐Frénay, Anne-Caroline Papeix, Patrick Vermersch, Katrin Bachus-Banaschak, Martin Berghoff, Florian Bethke, H. J. BOLDT, Andrew Chan, Hans‐Christoph Diener, Ilonka Eisensehr, Peter Emrich, B. Griewing, Judith Haas, Christoph Heesen, Frank Hoffmann, A. Hufnagel, Fedor Heidenreich, Ingo Kleiter, W. Lüer, Silke Marckmann-Böenke, Martin Marziniak, Martin Stangel, Patrick Oschmann, Thorsten Rosenkranz, Hauke Schneider, Veneta Siefjediers, Joachim Springub, Martin Stangel, Florian Stögbauer, Florian Then Bergh, Klaus Tiel‐Wilck, Konstanze Tinschert, Nikolaos Grigoriadis, Clementine Karageorgiou, Athanssios Kyritsis, Alexandros Papadimitriou, T. Thomaides, Nicholas Vlaikidis, Luis Fernando Salguero Gonzalez, D. Chon, Hugo Alfredo Ordoñez Sarg, CS Agrawal, Madhuri Behari, Velmurugendran Cu, Shamsher Dwivedee, Sudhir Kothari, Rahul Kulkarni, Suman Kushwaha, AK Meena, MM Mehndiratta, Subhash Chandra Mukherjee, Lekha Pandit, S Arun, Rakesh Shukla, K. Vijayan, Anat Achiron, Shlomo Flechter, Ron Milo, Adi Vaknin‐Dembinsky, Carlo Pozzilli, Vera Daskalovska, F G Farfán, Ricardo Alberto Rangel Guerra, Ildefonso Rodriguez Leyva, José Luis Oropeza de Alba, Raúl Arcega Revilla, José Flores‐Rivera, Mihail Gavriliuc, Stanislav Groppa, Olesea Odainic, E.A.C.M. Sanders, Raymond Hupperts, Deborah Mason, Paul Timmings, Ernest Willoughby, Anna Członkowska, Małgorzata Dorobek, Wiesław Drozdowski, Waldemar Fryze, Hanka Hertmanowska, Magdalena Kleczkowska, Jan Kochanowicz, Hubert Kwieciński, Przemysław Nowacki, Ryszard Podemski, Andrzej Potemkowski, Krzysztof Selmaj, Zbigniew Stelmasiak, A Wajgt, Tomasz Zieliński, Vera Daskalovska, Alexandru Ovidiu Bajenaru, Fior Dafin Mureșanu, Sanda Maria Nica, Mihaela Simu, Svetlana Miletić Drakulić, Čongor Nadj, Dragana Obradović, Slobodan Vojinović, Peter Turčáni, Edita Kahancová, Egon Kurča, L Lisý, Viliam Krajnak, Frans Hendrik Badenhorst, Judy Green, Jeannine M. Heckmann, Michael Isaacs, Ludwig Kappos, Michael Linnebank, Stefanie Müller, Nataliya Buchakchyys'ka, Alla Goloborodko, Tetyana Kobys, V. Lebedynets, N. V. Lytvynenko, Tetyana Nehrych, Igor Pasyura, Т. I. Ryabichenko, Nataliya Voloshina, Martin Duddy, Clive Hawkins, Richard W. Nicholas, Jacqueline Palace, Basil Sharrack, Eli Silber, Ben Turner, Ann Camac, Warren Chumley, Heidi Crayton, Shanker Dixit, Keith Edwards, Jeffrey English, Steven Freedman, Norman B. Gordon, Suzanne Gazda, Lawrence Goldstick, Paola Gottschalk, Erica Grazioli, William Grainger, Barbara Green, Bart Grelinger, Mark Gudesblatt, Ajay Gupta, Ghazala Hayat, Barry Hendin, Lily Jung Henson, Afif Hentati, Craig Herrman, Arthur Itkin, Todd J. Janus, Lloyd H. Kasper, Ellen Lathi, Ellen M. Mowry, G. Parry, Allan Perel, T. Hemanth Rao, Peter Riskind, Syed Rizvi, Howard Rossman, Thomas F. Scott, S. James Shafer, James R. Storey, Ben Thrower, M.E.E. van Rossen, William Tosches, Lori Trefts, Anthony P. Turel, Bianca Weinstock-Guttman, Ralf Gold, Ludwig Kappos, Douglas L. Arnold, Amit Bar‐Or, Gavin Giovannoni, Krzysztof Selmaj, Katherine Dawson, Phillip Gallacher, Carole Milla, Minhua Yang, Jack P. Antel, George L. Bakris, Raymond Chung, Peter R. Kowey, Chris H. Polman, John R. Richert, Burt Seibert, James S. Ware, David Brandes, David Brassat, Bruce A. Cohen, Ricarda Diem, Myla Goldman,
Abstract Background: Delayed-release dimethyl fumarate (DMF), indicated for the treatment of patients with relapsing-remitting multiple sclerosis (MS), is a disease-modifying therapy with potential immunomodulatory and neuroprotective effects. In clinical trials, DMF was associated with reduced white blood cell and absolute lymphocyte counts. Current US prescribing information recommends obtaining a complete blood count, including absolute lymphocyte count (ALC), before initiating and during DMF treatment. ...
Lippincott Williams & Wilkins
Produção Nacional
Revisado por pares
F. Anders, C. Chiappini, B. X. Santiago, H. J. Rocha–Pinto, L. Girardi, L. N. da Costa, M. A. G. Maia, Matthias Steinmetz, Ivan Minchev, M. Schultheis, C. Boeche, A. Miglio, J. Montalbán, Donald P. Schneider, Timothy C. Beers, Kátia Cunha, Carlos Allende Prieto, E. Balbinot, Dmitry Bizyaev, D. E. Brauer, J. Brinkmann, Peter M. Frinchaboy, A. E. García Pérez, Michael Hayden, Fred Hearty, Jon A. Holtzman, Jennifer A. Johnson, Karen Kinemuchi, Steven R. Majewski, Elena Malanushenko, Viktor Malanushenko, David L. Nidever, R. W. O’Connell, Kaike Pan, A. C. Robin, Ricardo P. Schiavon, Matthew Shetrone, M. F. Skrutskie, Verne V. Smith, Keivan G. Stassun, Gail Zasowski,
Context. The Apache Point Observatory Galactic Evolution Experiment (APOGEE) features the first multi-object high-resolution fiber spectrograph in the near-infrared ever built, thus making the survey unique in its capabilities: APOGEE is able to peer through the dust that obscures stars in the Galactic disc and bulge in the optical wavelength range. Here we explore the APOGEE data included as part of the Sloan Digital Sky Survey's 10th data release (SDSS DR10).
Tópico(s): Astronomy and Astrophysical Research
2014 - EDP Sciences | Astronomy and Astrophysics
Produção Nacional
Revisado por pares
F. Anders, C. Chiappini, Thaíse S. Rodrigues, A. Miglio, J. Montalbán, B. Mosser, L. Girardi, M. Valentini, A. Noels, T. Morel, Jennifer A. Johnson, M. Schultheis, F. Baudin, R. Peralta, S. Hekker, N. Themeßl, T. Kallinger, R. A. García, S. Mathur, A. Baglin, B. X. Santiago, Marie Martig, Ivan Minchev, Matthias Steinmetz, L. N. da Costa, M. A. G. Maia, Carlos Allende Prieto, Kátia Cunha, Timothy C. Beers, Courtney R. Epstein, A. E. García Pérez, D. A. García–Hernández, Paul Harding, Jon A. Holtzman, Steven R. Majewski, Szabolcs Mészáros, David L. Nidever, Kaike Pan, Marc H. Pinsonneault, Ricardo P. Schiavon, Donald P. Schneider, Matthew Shetrone, Keivan G. Stassun, O. Zamora, Gail Zasowski,
With the advent of the space missions CoRoT and Kepler, it has become feasible to determine precise asteroseismic masses and ages for large samples of red-giant stars. In this paper, we present the CoRoGEE dataset -- obtained from CoRoT lightcurves for 606 red giant stars in two fields of the Galactic disc which have been co-observed for an ancillary project of APOGEE. We have used the Bayesian parameter estimation code PARAM to calculate distances, extinctions, masses, and ages for these stars in ...
Tópico(s): Astrophysics and Star Formation Studies
2016 - EDP Sciences | Astronomy and Astrophysics