Pedro Sá Pinto, Ricardo Taipa, Bruno Moreira, Carlos Correia, Manuel Melo Pires,
Abstract Acute hemorrhagic leukoencephalitis (AHLE) is a rare and fulminant demyelinating disease considered to be the most severe form of acute disseminated encephalomyelitis (ADEM). A 70‐year‐old man was admitted to our emergency department (ED) after 1 week of unspecific abdominal symptoms and moderate fever in the first 3 days. Within the ED he developed a rapid onset coma and flaccid tetraparesis. Cerebrospinal fluid (CSF) analysis showed mild polymorphonuclear pleocytosis and magnetic resonance ...
Tópico(s): Long-Term Effects of COVID-19
2011 - Wiley | Journal of Magnetic Resonance Imaging
Produção Nacional
Revisado por pares
Vânia Hungria, Edvan de Queiroz Crusoé, Rosane Bittencourt, Ângelo Maiolino, Roberto Magalhães, Jairo do Nascimento Sobrinho, Jorge Vaz Pinto, Ricardo Coutinho Fortes, Eloisa De Sá Moreira, Paula Yurie Tanaka,
The treatment of patients with relapsed and/or refractory multiple myeloma has improved considerably in the last 15 years, after the introduction of proteasome inhibitors and immunomodulatory drugs. The first clinical trials with new proteasome inhibitors have produced exciting results, particularly those comparing triplet regimens with standard doublet regimens, with a gain in progression-free survival accompanied by an acceptable safety profile and either similar or better health-related quality ...
Tópico(s): Protein Degradation and Inhibitors
2018 - Elsevier BV | Hematology Transfusion and Cell Therapy
Sara Cavaco, Steven W. Anderson, Manuel Correia, Marina Magalhães, Cláudia Pereira, Assunção Tuna, Ricardo Taipa, Pedro Sá Pinto, Claudia Mendoza Pinto, Romeu Cruz, António Bastos Lima, Alexandre Castro‐Caldas, António Martins da Silva, Hanna Damásio,
Acquisition of new perceptual–motor skills depends on multiple brain areas, including the striatum. However, the specific contribution of each structure to this type of learning is still poorly understood. Focusing on the striatum, we proposed (a) to replicate the finding of impaired rotary pursuit (RP) and preserved mirror tracing (MT) in Huntington's disease (HD); and (b) to further explore this putative learning dissociation with other human models of striatal dysfunction (i.e., Parkinson's disease ...
Tópico(s): Botulinum Toxin and Related Neurological Disorders
2010 - Taylor & Francis | Journal of Clinical and Experimental Neuropsychology
Produção Nacional
Revisado por pares
Hamilton Roschel, Manoel Neves-Junior, Bruno Gualano, Renato Barroso, Christiano Robles, Ana Lúcia de Sá Pinto, Ricardo Fuller, Fernanda Rodrigues Lima,
Quadriceps weakness is an important risk factor for osteoarthritis of the knee [ 1 Mikesky A.E. Mazzuca S.A. Brandt K.D. Perkins S.M. Damush T. Lane K.A. Effects of strength training on the incidence and progression of knee osteoarthritis. Arthritis Rheum. 2006; 55: 690-699 Crossref PubMed Scopus (199) Google Scholar , 2 Lange A.K. Vanwanseele B. Fiatarone Singh M.A. Strength training for treatment of osteoarthritis of the knee: a systematic review. Arthritis Rheum. 2008; 59: 1488-1494 Crossref PubMed ...
Tópico(s): Rheumatoid Arthritis Research and Therapies
2011 - Elsevier BV | Physiotherapy
Ada D. Vatulescu, Ana S. Fortunato, Maria Cláudia Sá, Sara Amâncio, Cândido Pinto Ricardo, P. Jackson,
Changes in apoplastic peroxidases during auxin-induced in vitro rooting of cultured grapevine (Vitis vinifera L. cv. Touriga) stems have been studied. The largest increase in peroxidase activity (EC 1.11.1.7) was associated with the early stages of root initiation and could be attributed to an increase in activity of an apoplastic 36 kDa cationic peroxidase (PxB2). Relative to other peroxidases, PxB2 demonstrated high indole-3-acetic acid (IAA) oxidase activity and apparently contributed the majority ...
Tópico(s): Plant nutrient uptake and metabolism
2004 - Elsevier BV | Plant Physiology and Biochemistry
Produção Nacional
Revisado por pares
Simone Caetano Morale de Oliveira, Aarão Mendes Pinto-Neto, Juvenal Ricardo Navarro Góes, Délio Marques Conde, Danielle Santos-Sá, Lúcia Costa‐Paiva,
RACIONAL: A constipação intestinal é mais freqüente na população feminina, apresentando aumento da prevalência com o passar dos anos. Existem poucos estudos que estimaram sua prevalência em mulheres na pós-menopausa. OBJETIVO: Investigar a prevalência e os fatores associados à constipação intestinal em mulheres na pós-menopausa. PACIENTES E MÉTODOS: Estudo de corte transversal com mulheres na pós-menopausa e idade superior a 45 anos. Foram incluídas 100 mulheres atendidas no Ambulatório de Menopausa ...
Tópico(s): Anorectal Disease Treatments and Outcomes
2005 - Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE) | Arquivos de Gastroenterologia
Produção Nacional
Revisado por pares
Guilherme Fleury Perini, Thaís Fischer, Rafael Dezen Gaiolla, Talita Bueno Rocha, Marcelo Bellesso, Larissa Lane Cardoso Teixeira, Márcia Torresan Delamain, Adriana Alves de Souza Scheliga, Glaciano Ribeiro, Jorge Vaz Pinto Neto, Otávio Baiocchi, André Abdo, Celso Arrais‐Rodrigues, Laura Fogliatto, Ricardo de Sá Bigni, Rony Schaffel, Irène Biasoli, Juliana Pereira, Samir Kanaan Nabhan, Cármino Antônio De Souza, Carlos Chiattone,
The novel Coronavirus (CoVid-19) outbreak is now consider a world pandemic, affecting more than 1,300,000 people worldwide. Cancer patients are in risk for severe disease, including a higher risk of intensive care unit (ICU) admission, need for invasive ventilation or death. Management of patients with lymphoid malignancies can be challenging during the outbreak, due to need of multiple hospital visits and admissions, immunosuppression and need for chemotherapy, radiotherapy and stem cell transplantation. ...
Tópico(s): Economic and Financial Impacts of Cancer
2020 - Elsevier BV | Hematology Transfusion and Cell Therapy
Produção Nacional
Revisado por pares
Manoel Neves, Bruno Gualano, Hamilton Roschel, Ricardo Fuller, Fabiana Braga Benatti, Ana Lúcia de Sá Pinto, Fernanda Rodrigues Lima, Rosa Maria Rodrigues Pereira, Antônio Herbert Lancha, Eloísa Bonfá,
Introduction: The aim of this study was to investigate the efficacy of creatine (CR) supplementation combined with strengthening exercises in knee osteoarthritis (OA). Methods: A randomized, double-blind, placebo-controlled trial was performed. Postmenopausal women with knee OA were allocated to receive either CR (20 g·d−1 for 1 wk and 5 g·d−1 thereafter) or placebo (PL) and were enrolled in a lower limb resistance training program. They were assessed at baseline (PRE) and after 12 wk (POST). The primary ...
Tópico(s): Muscle metabolism and nutrition
2011 - Lippincott Williams & Wilkins | Medicine & Science in Sports & Exercise
Akli Benali, Ana R. Ervilha, Ana C. L. Sá, Paulo M. Fernandes, Renata M.S. Pinto, Ricardo M. Trigo, José M. C. Pereira,
Predicting wildfire spread is a challenging task fraught with uncertainties. 'Perfect' predictions are unfeasible since uncertainties will always be present. Improving fire spread predictions is important to reduce its negative environmental impacts. Here, we propose to understand, characterize, and quantify the impact of uncertainty in the accuracy of fire spread predictions for very large wildfires. We frame this work from the perspective of the major problems commonly faced by fire model users, ...
Tópico(s): Flood Risk Assessment and Management
2016 - Elsevier BV | The Science of The Total Environment
Jorge Sá Silva, Tiago Camilo, P. da F. Pinto, Ricardo Ruivo, André Rodrigues, Filipa Gaudêncio, Fernando Boavida,
Multicast potentially optimises bandwidth consumption and node resources, when several users simultaneously participate in a communication session. Nevertheless, contrary to the expectations, IP multicast has not experienced widespread deployment, with the exception of IPTV. On the other hand, emerging Wireless Sensor Network (WSN) applications could greatly benefit from multicast and constitute another field where multicast can be an effective and efficient technique. The questions are: do multicast ...
Tópico(s): Mobile Ad Hoc Networks
2008 - Academy Publisher | Journal of Networks
Produção Nacional
Revisado por pares
Rodrigo Ferraz, Bruno Gualano, R. W. P. Rodrigues, Ceci Obara Kurimori, Ricardo Fuller, Fernanda Rodrigues Lima, Ana Lúcia de Sá‐Pinto, Hamilton Roschel,
Purpose Evaluate the effects of a low-intensity resistance training (LI-RT) program associated with partial blood flow restriction on selected clinical outcomes in patients with knee osteoarthritis (OA). Methods Forty-eight women with knee OA were randomized into one of the three groups: LI-RT (30% one repetition maximum [1-RM]) associated (blood flow restriction training [BFRT]) or not (LI-RT) with partial blood flow restriction, and high-intensity resistance training (HI-RT, 80% 1-RM). Patients underwent ...
Tópico(s): Knee injuries and reconstruction techniques
2017 - Lippincott Williams & Wilkins | Medicine & Science in Sports & Exercise
Lúcia Lacerda, Olga Amaral, Ricardo Mouro Pinto, Johannes M. F. G. Aerts, Clara Sá-Miranda,
Summary The mutation N370S accounts for 63% of the mutated glucocerebrosidase alleles of Portuguese type 1 Gaucher patients. It has been shown previously that this mutation is linked to the Pv1.1 − form of the PvuII polymorphism and suggested that the N370S mutation in glucocerebrosidase alleles has an Ashkenazi Jewish origin. We have found that in Portuguese type 1 Gaucher patients this mutation is also invariably associated with the Pv1.1 − haplotype, despite the fact that there is no evidence of ...
Tópico(s): Carbohydrate Chemistry and Synthesis
1993 - Springer Science+Business Media | Journal of Inherited Metabolic Disease
Ana C. L. Sá, Akli Benali, Paulo M. Fernandes, Renata M.S. Pinto, Ricardo M. Trigo, Michele Salis, Ana Russo, Sónia Jerez, Pedro M. M. Soares, Wilfrid Schroeder, José M. C. Pereira,
The recognized shortcomings of fire spread modeling systems and the widespread use of their outcomes in fire management decisions render the evaluation of fire simulation results crucial for model calibration and improvement. Additionally, new methods are essential to avoid model misapplication in fuel and fire management decision processes. This study proposes an exploratory evaluation framework of fire growth simulations using satellite active fire data. It uses nine very large fires that occurred ...
Tópico(s): Flood Risk Assessment and Management
2017 - Elsevier BV | Remote Sensing of Environment
Produção Nacional
Revisado por pares
Manoel Neves, Bruno Gualano, Hamilton Roschel, Fernanda Rodrigues Lima, Ana Lúcia de Sá‐Pinto, Antônio Carlos Seguro, Maria Heloísa Massola Shimizu, Marcelo Tatit Sapienza, Ricardo Fuller, Antônio Herbert Lancha, Eloísa Bonfá,
We aimed to investigate whether creatine supplementation affects the measured glomerular filtration rate in postmenopausal women (age, 58 ± 3 years). Subjects were randomly assigned to receive either creatine (20 g·day(-1) for 1 week and 5 g·day(-1) thereafter) or a placebo. Kidney function was assessed at baseline and after 12 weeks. [(51)Cr]EDTA clearance remained unchanged (CR-PRE: 86.16 ± 14.36 mL·min(-1) per 1.73 m(2), POST: 87.25 ± 17.60 mL·min(-1) per 1.73 m(2); PL-PRE: 85.15 ± 8.54 mL·min(-1) per 1.73 ...
Tópico(s): Muscle metabolism and nutrition
2011 - NRC Research Press | Applied Physiology Nutrition and Metabolism
Produção Nacional
Revisado por pares
Olga Maria Pinto de Lima, Ricardo de Oliveira‐Souza, Omar da Rosa Santos, Pedro Araújo de Moraes, Leonardo Fontenelle de Sá, Osvaldo J. M. Nascimento,
Clinical and experimental evidence suggests that chronic obstructive pulmonary disease (COPD) is associated with a variety of mental symptoms that range from cognitive slowing to mental confusion and dementia.To test the hypothesis that COPD leads to cognitive impairment in the absence of acute confusion or dementia.The global cognitive status of 30 patients with COPD without dementia or acute confusion and 34 controls was assessed with a Brazilian version of the Mini-Mental State Exam (MMSE).The ...
Tópico(s): Neuroscience of respiration and sleep
2007 - Thieme Medical Publishers (Germany) | Arquivos de Neuro-Psiquiatria
Renata M.S. Pinto, Akli Benali, Ana C. L. Sá, Paulo M. Fernandes, Pedro M. M. Soares, Rita M. Cardoso, Ricardo M. Trigo, José M. C. Pereira,
An approach to predict fire growth in an operational setting, with the potential to be used as a decision-support tool for fire management, is described and evaluated. The operational use of fire behaviour models has mostly followed a deterministic approach, however, the uncertainty associated with model predictions needs to be quantified and included in wildfire planning and decision-making process during fire suppression activities. We use FARSITE to simulate the growth of a large wildfire. Probabilistic ...
Tópico(s): Fire dynamics and safety research
2016 - Springer International Publishing | SpringerPlus
Cristiano Barros de Melo, Marcos Eielson Pinheiro de Sá, Antonizete dos Reis Souza, Anapolino Macedo de Oliveira, Pedro Moacyr Pinto Coelho Mota, Paulo Ricardo Campani, Janaína Oliveira Luna, Sérgio Cabral Pinto, Fábio Fraga Schwingel, Concepta McManus, Luiza Seixas,
To the Editor: International air travel can lead to the rapid global dissemination of infectious agents. Unlike products and byproducts of animal origin imported between countries under agreements that legally establish sanitary standards, products introduced into a country illegally or irregularly do not follow specific standards and can come from any source, thereby posing a risk to the health status of a country. Animal products transported clandestinely in baggage can contain infectious agents ...
Tópico(s): Microbial infections and disease research
2014 - Centers for Disease Control and Prevention | Emerging infectious diseases
Produção Nacional
Revisado por pares
Maurício Luiz de Mello Vieira Leite, Leandro Ricardo Rodrigues de Lucena, Manoela Gomes da Cruz, Eduardo Henrique de Sá Júnior, Vicente José Laamon Pinto Simões,
Leaf area measurements are of the main parameters used in agronomic studies to evaluate plant growth. The current study used a non-destructive method based on linear leaf dimensions (length and width) to select the regression model to estimate millet (Pennisetum glaucum) leaf area. For two millet genotype (IPA BULK 1 BF and ADR 300) 128 randomly-chosen leaves were measured at different vegetative growth stages. Measures of length and width of each leaf were made using digital calipers. Leaf area was ...
Tópico(s): Remote Sensing in Agriculture
2019 - Editora da Universidade Estadual de Maringá (Eduem) | Acta Scientiarum Animal Sciences
Produção Nacional
Revisado por pares
Ana Paula Pinto, Flávia Barbieri Bacha, Bethânia S. Santos, David Driemeier, Nádia Aline Bobbi Antoniassi, Nickolly L.K. de Sá Ribas, Ricardo A.A. Lemos,
Canids are the main hosts of Neospora caninum, but cattle, (sheep, goats and horses may serve as intermediary hosts. N. caninum infection of pregnant intermediary hosts may provoke abortion and neonatal infections. This study is the first to report lamb abortion associated with N. caninum in Mato Grosso do Sul. Epidemiological data were obtained from interviews with sheep producers. For microscopic examination, fragments of different organs removed from 4 sheep fetuses, aborted and necropsied, were ...
Tópico(s): Viral Infections and Vectors
2012 - Colégio Brasileiro de Patologia Animal (CBPA) | Pesquisa Veterinária Brasileira
Ricardo Taipa, Assunção Tuna, Joana Damásio, Pedro Sá Pinto, Sara Cavaco, Sónia Pereira, Gabriel Milterberger-Miltenyi, Daniela Galimberti, Manuel Melo Pires,
Frontotemporal lobar degeneration (FTLD) refers to a clinically, pathologically, and genetically heterogeneous group of dementias that arises from the degeneration of the frontal and temporal lobes. Mutations in the progranulin gene (GRN) are a major cause of FTLD with TDP-43 inclusions. Herein, we describe the clinical, neuropathological, and genetic findings in a case of autosomal dominant behavioral variant of frontotemporal dementia (bvFTD) with asymmetrical parkinsonism and prominent visuospatial ...
Tópico(s): Parkinson's Disease Mechanisms and Treatments
2012 - IOS Press | Journal of Alzheimer s Disease
Produção Nacional
Revisado por pares
Simone Caetano Morale de Oliveira, Aarão Mendes Pinto-Neto, Délio Marques Conde, Juvenal Ricardo Navarro Góes, Danielle Santos-Sá, Gislaine Aparecida Fonsechi‐Carvasan, Lúcia Costa‐Paiva,
OBJETIVOS.Investigar a prevalência e os fatores associados à constipação intestinal em mulheres na pós-menopausa e avaliar o grau de concordância entre diferentes critérios diagnósticos.MÉTODOS.Estudo de corte transversal com 100 mulheres na pós-menopausa e idade superior a 45 anos.Foram aplicados os critérios de Roma II, freqüência de evacuações por semana e auto-avaliação.Avaliaram-se as características sociodemográficas e clínicas com análise descritiva das mesmas.Posteriormente calculou-se o ...
Tópico(s): Menstrual Health and Disorders
2005 - Brazilian Medical Association | Revista da Associação Médica Brasileira
Paulo Cardoso, Tiago D. G. Nunes, Ricardo J.B. Pinto, Carina Sá, Diana Matos, Etelvina Figueira,
Tópico(s): Plant Micronutrient Interactions and Effects
2020 - Springer Science+Business Media | Ecotoxicology
Andrea Cruz, Raquel B. Queirós, Catarina M. Abreu, Catarina Barata, Rosa Fernandes, Rufino Silva, António Francisco Ambrósio, Ricardo Soares-dos-Reis, Joana Guimarães, María José Sá, João B. Relvas, P. P. Freitas, Inês Mendes Pinto,
Inflammation associated with cancer, neurodegenerative, ocular, and autoimmune diseases has a considerable impact on public health. Tumor necrosis factor alpha (TNFα) is a key mediator of inflammatory responses, responsible for many of the systemic manifestations during the inflammatory process. Thus, inhibition of TNFα is a commonplace practice in the treatment of these disorders. Successful therapy requires the ability to determine the appropriate dose of anti-TNFα drugs to be administered in a ...
Tópico(s): Antimicrobial Peptides and Activities
2019 - American Chemical Society | ACS Chemical Neuroscience
Adriana Sá Pinto, Valcides Jose Pio Alves, António Oliveira, Ricardo Castro, J G L Pereira,
Tópico(s): Management of metastatic bone disease
2017 - Elsevier BV | Radiography
Produção Nacional
Revisado por pares
D. de Sá Cavalcante, M. G. Castro, Ana Rosa Pinto Quidute, Manoel Ricardo Alves Martins, Adília Mirela Pereira Lima Cid, P.G. de Barros Silva, Jim C. Williams, Frederico Sampaio Neves, Thyciana Rodrigues Ribeiro, Fábio Wildson Gurgel Costa,
Sheehan's syndrome (SHS) is a rare condition related to the risk of osteoporosis and evaluation of bone texture imaging features on panoramic radiographs would be suitable for this condition, which was the aim of the present study. Fractal dimension, lacunarity, and trabecular morphologic aspects were significantly altered in these patients.SHS is an important public health problem particularly in developing countries. It is characterized as postpartum hypopituitarism secondary to obstetric complications- ...
Tópico(s): Genomics and Rare Diseases
2019 - Springer Science+Business Media | Osteoporosis International
Catarina M. Abreu, Ricardo Soares-dos-Reis, Pedro Melo, João B. Relvas, Joana Guimarães, María José Sá, Andrea Cruz, Inês Mendes Pinto,
Neuroinflammation plays a critical role in the onset and progression of many neurological disorders, including Multiple Sclerosis, Alzheimer's and Parkinson's diseases. In these clinical conditions the underlying neuroinflammatory processes are significantly heterogeneous. Nevertheless, a common link is the chronic activation of innate immune responses and imbalanced secretion of pro and anti inflammatory mediators. In light of this, the discovery of robust biomarkers is crucial for screening, early ...
Tópico(s): Salivary Gland Disorders and Functions
2018 - Frontiers Media | Frontiers in Molecular Neuroscience
Ricardo Janeiro, Teresa Pereira, Luı́s Pinto Ferreira, José Carlos Sá, F.J.G. Silva,
This paper focuses on the logistics activity of the Outlet Retail industry of accessories and clothing items produced by a Portuguese fashion company, operated by an also Portuguese Third-Party Logistics providers (3PL). The main goal of this study is to address and analyze the current business and process model used by the Portuguese 3PL, to compare it with other existing models within the state-of-art, and to design a new conceptual model for 3PL's reverse logistics activities in the Clothing and ...
Tópico(s): Outsourcing and Supply Chain Management
2020 - Elsevier BV | Procedia Manufacturing
Produção Nacional
Revisado por pares
Dionísio Henrique Carvalho de Sá Só Martins, Denys Pestana Viana, Amaro A. de Lima, Milena F. Pinto, Luís Tarrataca, Fabrício Lopes e Silva, Ricardo H. R. Gutiérrez, Thiago de M. Prego, Ulisses A. Monteiro, Diego B. Haddad,
Tópico(s): Advanced machining processes and optimization
2021 - Springer Science+Business Media | The International Journal of Advanced Manufacturing Technology
Produção Nacional
Revisado por pares
Fábio Henrique de Gobbi Porto, Artur Martins Coutinho, Fábio Duran, Ana Lúcia de Sá Pinto, Bruno Gualano, Carlos Alberto Buchpiguel, Geraldo F. Busatto, Ricardo Nitríni, Sônia Maria Dozzi Brucki,
Aerobic training (AT) is a promising intervention to improve cognitive functioning. However, its modulatory effects on brain networks are not yet entirely understood. Sixty-five subjects with mild cognitive impairment performed a moderate intensity, 24-week AT program. Differences in resting regional brain glucose metabolism (rBGM) with FDG-PET were assessed before and after AT on a voxel-by-voxel basis. Structural equation modeling was used to create latent variables based on regions with significant ...
Tópico(s): Optical Imaging and Spectroscopy Techniques
2018 - Elsevier BV | NeuroImage Clinical
Ricardo Taipa, Sofia Pereira das Neves, Ana Luísa Sousa, Joana Fernandes, Cláudia Pinto, Ana Paula Correia, Ernestina Santos, Pedro Sá Pinto, Paula Carneiro, Patrício Costa, Diana Santos, Isabel Alonso, Joana Almeida Palha, Fernanda Marques, Sara Cavaco, Nuno Sousa,
Cumulative data suggest that neuroinflammation plays a prominent role in Alzheimer's disease (AD) pathogenesis. The purpose of this work was to assess if patients with AD present a specific cerebrospinal fluid (CSF) cytokine profile and if it correlates to disease progression. We determined the levels of 27 cytokines in CSF of patients with AD and compared them with patients with frontotemporal dementia and nondemented controls. In addition, we correlated the cytokine levels with cognitive status ...
Tópico(s): Tryptophan and brain disorders
2019 - Elsevier BV | Neurobiology of Aging