Yajing Zhang, Fangfang Liu, Chengli Zhang, Meijing Ren, Manchao Kuang, Ting Xiao, Xuebing Di, Lin Feng, Li Fu, Shujun Cheng,
... Marchal K. De Moor B. Foijer F. Te Riele H. Beullens M. Bollen M. Mathieu C. Bouillon R. Verstuyf A. Characterization of the condensin component Cnap1 and protein kinase Melk as novel E2F target genes down-regulated by 1,25-dihydroxyvitamin D3.J Biol ...
Tópico(s): Cancer-related Molecular Pathways
2019 - Elsevier BV | American Journal Of Pathology
Myunggon Ko, Jeongeun Ahn, Changjin Lee, Heekyoung Chung, Sung Ho Jeon, Hee Yong Chung, Rho Hyun Seong,
... lymphogenesis (3Bain G. Robanus Maandag E.C. te Riele H.P. Feeney A.J. Sheehy A. Schlissel ... van Roon M. van der Valk M. te Riele H.P.J. Berns A. Murre C. Cell. ... G. Engel I. Robanus Maandag E.C. te Riele H.P. Voland J.R. Sharp L.L. ... G. Engel I. Robanus Maandag E.C. te Riele H.P. Voland J.R. Sharp L.L. ... G. Engel I. Robanus Maandag E.C. te Riele H.P. Voland J.R. Sharp L.L. ... thymocytes, Id3 proteins were rapidly induced and thereby down-regulated E protein DNA binding to promote β- ... element in the SRG3 promoter, resulting in SRG3 down-regulation. Additionally, ectopic overexpression of Id3 by the ...
Tópico(s): NF-κB Signaling Pathways
2004 - Elsevier BV | Journal of Biological Chemistry
Lieve Verlinden, Guy Eelen, Ine Beullens, Mark Van Camp, Paul Van Hummelen, Kristof Engelen, Ruth Van Hellemont, Kathleen Marchal, Bart De Moor, Floris Foijer, Hein te Riele, Monique Beullens, Mathieu Bollen, Chantal Mathieu, Roger Bouillon, Annemieke Verstuyf,
1,25-Dihydroxyvitamin D3 (1,25(OH)2D3) has potent antiproliferative effects characterized by a hampered G1/S transition. cDNA microarrays were used to monitor expression of 21,492 genes in MC3T3-E1 mouse osteoblasts at 1, 6, 12, 24, and 36 h after treatment with 1,25(OH)2D3. Statistical analysis revealed a cluster of genes that were strongly down-regulated by 1,25(OH)2D3 and which not only function in cell cycle regulation and DNA replication but also mediate checkpoint control, DNA repair, chromosome ...
Tópico(s): Vitamin D Research Studies
2005 - Elsevier BV | Journal of Biological Chemistry
Jun Hyun Kim, Channabasavaiah B. Gurumurthy, Mayumi Naramura, Ying Zhang, Andrew T. Dudley, Lynn Doglio, Hamid Band, Vimla Band,
... Spektor A. Lents N.H. Cam H. te Riele H. Scime A. Rudnicki M.A. Young R. ... J.H. Catchpole S. Watson R.J. te Riele H. Dynlacht B.D. Genes Dev. 2002; 16: ... analyze further whether other E2F target genes are down-regulated in Ecd-null cells. In view of ... cdc2. Notably, these E2F target genes were also down-regulated in Ecd-null MEFs, whereas cyclin D1 ... level. Given that Ecd deletion led to a down-regulation of E2F target genes and reduced the ... a GST pulldown assay. Purified Ecd was pulled down by a GST-Rb fusion protein that incorporated ...
Tópico(s): Tardigrade Biology and Ecology
2009 - Elsevier BV | Journal of Biological Chemistry
Yong Kim, Amit Deshpande, Yan‐Shan Dai, Jeffrey Kim, Anne Lindgren, Anne E. Conway, Amander T. Clark, David T. Wong,
... J.C. Dannenberg J.H. Berns A. te Riele H. Genes Dev. 1998; 12: 1599-1609Crossref PubMed ... J.H. van Rossum A. Schuijff L. te Riele H. Genes Dev. 2000; 14: 3051-3064Crossref PubMed ... of pRb S788A in Cdk2ap1−/− mESCs were the down-regulation of Oct3/4 and up-regulation of ...
Tópico(s): Renal and related cancers
2009 - Elsevier BV | Journal of Biological Chemistry
... van Roon M. van der Valk M. te Riele H. Berns A. Murre C. Cell. 1994; 79: ... van Roon M. van der Valk M. te Riele H. Berns A. Murre C. Cell. 1994; 79: ... fragment, a forward (sense) primer starting 1 nucleotide down from the mutant and a backward (antisense) primer ...
Tópico(s): Ubiquitin and proteasome pathways
2001 - Elsevier BV | Journal of Biological Chemistry
John J. Caterina, Ziedonis Skobe, Joanne Shi, Yanli Ding, James P. Simmer, Henning Birkedal‐Hansen, John D. Bartlett,
... 39van der Lugt N. Maandag E.R. te Riele H. Laird P.W. Berns A. Gene. 1991; ... 39van der Lugt N. Maandag E.R. te Riele H. Laird P.W. Berns A. Gene. 1991; ...
Tópico(s): Oral microbiology and periodontitis research
2002 - Elsevier BV | Journal of Biological Chemistry
Michael T. Chin, Koji Maemura, Shinya Fukumoto, Mukesh K. Jain, Matthew D. Layne, Masafumi Watanabe, Chung-Ming Hsieh, Mu-En Lee,
... G. Engel I. Robanus Maandag E.C. te Riele H.P. Voland J.R. Sharp L.L. ... cardiomyocytes and vascular smooth muscle cells but was down-regulated in adult heart when cardiac myocytes became ... abundant in fetal rat hearts and is markedly down-regulated 2 days after birth. It is noteworthy that down-regulation of CHF1 correlates with down-regulation of cyclin A, cell cycle withdrawal, and ... Scopus (191) Google Scholar). Interestingly, CHF1 expression is down-regulated in isolated rat hearts as a function of age (Fig. 7). The time course of down-regulation correlates with down-regulation of cyclin A ...
Tópico(s): ATP Synthase and ATPases Research
2000 - Elsevier BV | Journal of Biological Chemistry
Hongjuan Cui, Bo Hu, Tai Li, Jun Ma, Goleeta N. Alam, William T. Gunning, Han‐Fei Ding,
... K van Roon M Robanus-Maandag E te Riele H van der Valk M Deschamps J Sofroniew ... Google Scholar were used in overexpression studies. For down-regulation of Bmi-1, synthesized 64-bp oligonucleotides ... samples (eg, control versus Bmi-1 overexpression or down-regulation), using the data analysis tools provided by ... retroviruses produced from either construct were able to down-regulate Bmi-1 expression in all of the ... cells infected with Bmi-1 siRNA retroviruses showed down-regulation of Bmi-1 by 70 to 80% ( ... data not shown). Together, these results indicate that down-regulation of Bmi-1 inhibits the clonogenic activity ...
Tópico(s): Zebrafish Biomedical Research Applications
2007 - Elsevier BV | American Journal Of Pathology
Xueli Fan, Yun Liu, Jason J. Chen,
... Martins C. Dannenberg J.H. Berns A. te Riele H. Bernards R. Oncogene. 2000; 19: 4822-4827Crossref ... induction of cell proliferation by BPV-1 E7. Down-regulation of p27 and Up-regulation of Cyclin ... Cdc25A, cyclin A, cyclin D1, cyclin E, and down-regulation of p27 (reviewed in Ref. 35Bartek J. ... to BPV-1 E7-induced cell proliferation. Furthermore, down-regulation of p27 by c-Myc resulted in ... Although it is well established that c-Myc down-regulates p27, a recent study suggests that p27 ... raises the possibility that BPV-1 E7 may down-regulate p27 to activate c-Myc. However, our ...
Tópico(s): Virus-based gene therapy research
2003 - Elsevier BV | Journal of Biological Chemistry
... Valk M.A. Robanus-Maandag E.C. te Riele H.P. Berns A.J.M. Borst P. ... Scholar), and boiled for 2 min to break down polymeric species. Purified mutant F434C/V982C was reconstituted ... structure of the TM domains. ATP hydrolysis slows down TMEA cross-linking of mutant L339C/V982C while ...
Tópico(s): HIV/AIDS drug development and treatment
2001 - Elsevier BV | Journal of Biological Chemistry
Nianxiang Zhang, Ramandeep Kaur, Xiaoyan Lu, Xi Shen, Lei Li, Randy J. Legerski,
... Takao M. Matsunaga T. Yoshino M. Ichikawa M. Riele H. Tsuchiya S. Tanaka K. Yasui A. DNA ... for each reaction. Immunodepletion, Co-immunoprecipitation, and Pull-down Assays—Immunodepletion and coimmunoprecipitation assays were performed as ... 9220Crossref PubMed Scopus (101) Google Scholar). For pull-down assays GST-tagged proteins were bound on glutathione- ...
Tópico(s): Genomics and Chromatin Dynamics
2005 - Elsevier BV | Journal of Biological Chemistry
Marleen Dekker, Sandra de Vries, Marieke Aarts, Robert G. Dekker, Conny Brouwers, Oliver T. Wiebenga, Niels de Wind, Erika Cantelli, Roberto Tonelli, Hein te Riele,
... of DNA mismatch repair (MMR). However, whereas transient down-regulation of the mismatch recognition protein MSH2 allowed ... dinucleotide substitution can effectively be achieved by transient down-regulation of the downstream MMR protein MLH1. By ...
Tópico(s): RNA Research and Splicing
2011 - Elsevier BV | Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
... Scholar3. Groeneweg J, Bhonsale A, James CA, te Riele AS, Dooijes D, Tichnell C, et al.. Clinical ... 10.1161/CIRCULATIONAHA.110.976936.LinkGoogle Scholar7. te Riele AS, James CA, Rastegar N, Bhonsale A, Murray ...
Tópico(s): Cardiac Arrhythmias and Treatments
2015 - Lippincott Williams & Wilkins | Circulation Cardiovascular Genetics
Jacob B. Hansen, Claus Jørgensen, Rasmus K. Petersen, Philip Hallenborg, Rita De Matteis, Hans Boye, Nataša Petrović, Sven Enerbäck, Jan Nedergaard, Saverio Cinti, Hein te Riele, Karsten Kristiansen,
... UCP-1 expression in brown adipose tissue. Finally, down-regulation of pRB expression accompanies transdifferentiation of white ...
Tópico(s): Peroxisome Proliferator-Activated Receptors
2004 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Marieke Aarts, Marleen Dekker, Sandra de Vries, Anja van der Wal, Hein te Riele,
... for the generation of mouse mutants using transient down regulation of the central MMR protein MSH2 by ...
Tópico(s): RNA Interference and Gene Delivery
2006 - Oxford University Press | Nucleic Acids Research
... J.H. Catchpole S. Watson R.J. te Riele H. Dynlacht B.D. Genes Dev. 2002; 16: ...
Tópico(s): Ubiquitin and proteasome pathways
2007 - Elsevier BV | Molecular Cell
Thomas Farkas, Klaus Hansen, Karin Holm, Jiří Lukáš, Jiří Bártek,
... J.H. van Rossum A. Schuijff L. te Riele H. Genes Dev. 2000; 14: 3051-3064Crossref PubMed ... and leupeptin (2.5 μg/ml)). One pull-down reaction contained an amount of fusion protein derived ...
Tópico(s): Cancer, Hypoxia, and Metabolism
2002 - Elsevier BV | Journal of Biological Chemistry
Alice Cavanaugh, Iwona Hirschler‐Laszkiewicz, Qiyue Hu, Miroslav Dundr, Tom Smink, Tom Misteli, Lawrence I. Rothblum,
... A. Alzuherri H.M. Dannenberg J.H. te Riele H. Grummt I. Voit R. White R.J. ... yeast cells, in which rDNA transcription has been down-regulated, there is a decrease in the association ...
Tópico(s): CRISPR and Genetic Engineering
2002 - Elsevier BV | Journal of Biological Chemistry
... and R.Kanaar, in preparation) and Pim1 (te Riele et al., 1990; Moynahan et al., 2001). The ...
Tópico(s): CRISPR and Genetic Engineering
2003 - Springer Nature | The EMBO Journal
... pi (x) - {\text {li}}(x) > 0 . This brings down Sherman Lehman’s bound on the smallest number ...
Tópico(s): Advanced Algebra and Geometry
1987 - American Mathematical Society | Mathematics of Computation
... reduce the rate of replication fork progression. Transient down‐regulation of various DNA repair genes by RNAi ...
Tópico(s): Advanced biosensing and bioanalysis techniques
2009 - Wiley | Journal of Cellular and Molecular Medicine
Henk Boender, H. J. J. te Riele,
... 80 digits, and that this crossover point goes down with the amount of available central memory. For ...
Tópico(s): Parallel Computing and Optimization Techniques
1996 - Taylor & Francis | Experimental Mathematics
Irsan Kooi, Berber M. Mol, Maarten P.G. Massink, Marcus C. de Jong, Pim de Graaf, Paul van der Valk, Hanne Meijers‐Heijboer, Gertjan J.L. Kaspers, Annette C. Moll, Hein te Riele, Jacqueline Cloos, Josephine C. Dorsman,
Background While RB1 loss initiates retinoblastoma development, additional somatic copy number alterations (SCNAs) can drive tumor progression. Although SCNAs have been identified with good concordance between studies at a cytoband resolution, accurate identification of single genes for all recurrent SCNAs is still challenging. This study presents a comprehensive meta-analysis of genome-wide SCNAs integrated with gene expression profiling data, narrowing down the list of plausible retinoblastoma ...
Tópico(s): Cancer Genomics and Diagnostics
2016 - Public Library of Science | PLoS ONE
Young‐Joo Lee, Bethany Swencki, Sarah A. Shoichet, Ramesh A. Shivdasani,
... Izon D. Hofhuis F. Robanus-Maandag E. te Riele H. van de Wetering M. Oosterwegel M. Wilson ...
Tópico(s): Epigenetics and DNA Methylation
1999 - Elsevier BV | Journal of Biological Chemistry
Germán Pérez-Juste, Ana Aranda,
... Valk M. Hooper M.L. Berns A. te Riele H. Nature. 1992; 359: 328-330Crossref PubMed Scopus ( ...
Tópico(s): Ubiquitin and proteasome pathways
1999 - Elsevier BV | Journal of Biological Chemistry
Mustafa Gerçek, Muhammed Gerçek, Sebastian Kant, Sakine Simsekyilmaz, Astrid Kassner, Hendrik Milting, Elisa A. Liehn, Rudolf E. Leube, Claudia A. Krusche,
... 1512-1520Crossref PubMed Scopus (776) Google Scholar, 6Te Riele A.S. James C.A. Philips B. Rastegar ...
Tópico(s): Cardiomyopathy and Myosin Studies
2017 - Elsevier BV | American Journal Of Pathology
Qiong Wu, Yaping Huang, Liya Gu, Zhijie Chang, Guo‐Min Li,
... der Valk M. van't Wout K. te Riele H. HNPCC-like cancer predisposition in mice through ...
Tópico(s): DNA Repair Mechanisms
2021 - Elsevier BV | Journal of Biological Chemistry
Wessel W. Wits, Gert Jan te Riele,
This paper presents a planar cooling strategy for advanced electronic applications using heat pipe technology. The principle idea is to use an array of relatively long heat pipes, whereby heat is disposed to a long section of the pipes. The proposed design uses 1 m long heat pipes and top cooling through a fan-based heat sink. Successful heat pipe operation and experimental performances are determined for seven heating configurations, considering active bottom, middle and top sections, and four ...
Tópico(s): Fluid Dynamics and Thin Films
2017 - Springer Science+Business Media | Heat and Mass Transfer
Wessel W. Wits, Gert Jan te Riele,
This paper presents a planar cooling strategy for rotating radar systems using heat pipe technology. The proposed design uses six 1 m long heat pipes in parallel oriented in an evaporator-down modus at an elevation angle of 85 deg. An analytical model based on conventional heat pipe limits is used to predict the performance taking into account both gravitational and centrifugal forces. The heat pipe array is mounted on a rotating platform of which both the mounting angle w.r.t. the rotational arm ...
Tópico(s): Fluid Dynamics and Heat Transfer
2019 - ASM International | Journal of Heat Transfer