Wafaa B. Alsoussi, Jackson S. Turner, James Brett Case, Haiyan Zhao, Aaron J. Schmitz, Julian Q. Zhou, Rita E. Chen, Tingting Lei, Amena A. Rizk, Katherine M. McIntire, Emma S. Winkler, Julie M. Fox, Natasha M. Kafai, Larissa B. Thackray, Ahmed O. Hassan, Fatima Amanat, Florian Krammer, Corey T. Watson, Steven H. Kleinstein, Daved H. Fremont, Michael Diamond, Ali H. Ellebedy,
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for millions of infections and hundreds of thousands of deaths globally. There are no widely available licensed therapeutics against SARS-CoV-2, highlighting an urgent need for effective interventions. The virus enters host cells through binding of a receptor-binding domain within its trimeric spike glycoprotein to human angiotensin-converting enzyme 2. In this article, we describe the generation and characterization of a ...
Tópico(s): Viral gastroenteritis research and epidemiology
2020 - American Association of Immunologists | The Journal of Immunology
Eric Song, Christopher M. Bartley, Ryan D. Chow, Thomas Ngo, Ruoyi Jiang, Colin R. Zamecnik, Ravi Dandekar, Rita P. Loudermilk, Yile Dai, Feimei Liu, Sara Sunshine, Jamin Liu, Wesley Wu, Isobel A. Hawes, Bonny D. Alvarenga, Trung Huynh, Lindsay McAlpine, Nur-Taz Rahman, Bertie Geng, Jennifer Chiarella, Benjamin Israelow, Chantal B. F. Vogels, Nathan D. Grubaugh, Arnau Casanovas‐Massana, Brett S. Phinney, Michelle Salemi, Jessa Alexander, Juan A. Gallego, Todd Lencz, Hannah Walsh, Anne E. Wapniarski, Subhasis Mohanty, Carolina Lucas, Jon Klein, Tianyang Mao, Ji-Eun Oh, Aaron M. Ring, Serena Spudich, Albert I. Ko, Steven H. Kleinstein, John E. Pak, Joseph L. DeRisi, Akiko Iwasaki, Samuel J. Pleasure, Michael R. Wilson, Shelli Farhadian,
Individuals with coronavirus disease 2019 (COVID-19) frequently develop neurological symptoms, but the biological underpinnings of these phenomena are unknown. Through single-cell RNA sequencing (scRNA-seq) and cytokine analyses of cerebrospinal fluid (CSF) and blood from individuals with COVID-19 with neurological symptoms, we find compartmentalized, CNS-specific T cell activation and B cell responses. All affected individuals had CSF anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ...
Tópico(s): COVID-19 Clinical Research Studies
2021 - Elsevier BV | Cell Reports Medicine
M. Marttila, Vilma‐Lotta Lehtokari, Steven B. Marston, Tuula A. Nyman, Christine Barnérias, Alan H. Beggs, Enrico Bertini, Özge Ceyhan-Birsoy, Pascal Cintas, Marion Gérard, Brigitte Gilbert‐Dussardier, Jacob S. Hogue, Cheryl Longman, B. Eymard, Moshe Frydman, Peter B. Kang, Lars Klinge, Hanna Kolski, Hanns Lochmüller, Laurent Magy, Véronique Manel, M. Mayer, Eugenio Mercuri, Kathryn N. North, Sylviane Peudenier-Robert, Helena Pihko, Frank J. Probst, Ricardo Reisin, William Stewart, Ana Lía Taratuto, Marjolein Visser, Ekkehard Wilichowski, J. Winer, Kristen L. Nowak, Nigel G. Laing, Tom Winder, Nicole Monnier, Nigel F. Clarke, Katarina Pelin, Mikaela Grönholm, Carina Wallgren‐Pettersson, Judy Savige, Hayat Dagher, Sue Povey, Heidi Ali, Siddhaling Urolagin, Ömer Gurarslan, Mauno Vihinen, Alexandre Hinzpeter, Alix de Becdelièvre, Éric Bieth, Christine Gameiro, Natacha Martin, Bruno Costes, Cathérine Costa, Abdel Aissat, Aurélie Lorot, V. Prulière‐Escabasse, Michel Goossens, Pascale Fanen, Emmanuelle Girodon, Paige Cooper, Heiko Reutter, Joachim Woelfle, Hartmut Engels, Dorothy K. Grange, Gijs van Haaften, Bregje W.M. van Bon, Alexander Hoischen, Colin G. Nichols, Luping Zhang, Lingxiang Hu, Yongchuan Chai, Xiuhong Pang, Tao Yang, Hao Wu, Héla Azaiez, Kevin T. Booth, Fengxiao Bu, P.L.M. Huygen, Seiji B. Shibata, Andrew Shearer, Diana L. Kolbe, Nicole C. Meyer, E. Ann Black-Ziegelbein, Richard Smith, Vahagn Makaryan, Elisabeth A. Rosenthal, A. A. na Bolyard, Merideth L. Kelley, Jennifer E. Below, Michael J. Bamshad, Kathryn M. Bofferding, Joshua D. Smith, Kati J. Buckingham, Laurence A. Boxer, Julia Skokowa, Karl Welte, Deborah A. Nickerson, Gail P. Jarvik, David C. Dale, Maria Chiara Scaini, Giovanni Minervini, Lisa Elefanti, Paola Ghiorzo, Lorenza Pastorino, Silvia Tognazzo, Simona Agata, Monica Quaggio, Daniela Zullato, Giovanna Bianchi‐Scarrà, Marco Montagna, Emma D’Andrea, Chiara Menin, Silvio C. E. Tosatto, Lucia Micale, Bartolomeo Augello, Claudia Maffeo, Angelo Selicorni, Federica Zucchetti, Carmela Fusco, Pasquelena De Nittis, Maria Teresa Pellico, Barbara Mandriani, Rita Fischetto, Loredana Boccone, Margherita Silengo, Elisa Biamino, Chiara Perrìa, Stefano Sotgiu, Gigliola Serra, Elisabetta Lapi, Marcella Neri, Alessandra Ferlini, Maria Pia Cavaliere, Pietro Chiurazzi, Matteo Della, Gioacchino Scarano, Francesca Faravelli, Paola Ferrari, Laura Mazzanti, Alba Pilotta, Maria Grazia Patricelli, Maria Francesca Bedeschi, Francesco Benedicenti, Paolo Prontera, Benedetta Toschi, Leonardo Salviati, Daniela Melis, E. Di Battista, Alessandra Vancini, Livia Garavelli, Leopoldo Zelante, Giuseppe Merla, Zhiqing Wang, Baoping Wu, Rebecca Mosig, Yulan Chen, Fei Ye, Yali Zhang, Wei Gong, Lanbo Gong, Fei Huang, Xinying Wang, Biao Nie, Haoxuan Zheng, Miao Cui, Yadong Wang, Juan Wang, Chudi Chen, Alexandros D. Polydorides, David Zhang, John A. Martignetti, Bo Jiang, Carl Schubert, Anders Pryds, Shemin Zeng, Yajing Xie, K. Bailey Freund, Richard F. Spaide, John C. Merriam, Irene Barbazetto, Jason S. Slakter, Stanley Chang, Inger Christine Munch, Arlene V. Drack, Jasmine Hernández, Suzanne Yzer, Joanna E. Merriam, Allan Linneberg, Michael Larsen, Lawrence A. Yannuzzi, Robert F. Mullins, Rando Allikmets, Phillipa J. Lamont, William Wallefeld, David Hilton‐Jones, Bjarne Udd, Zohar Argov, Alexandru Barboi, Carsten Bönneman, Kym M. Boycott, Kate Bushby, Anne M. Connolly, Nicholas P. Davies, Gerald F. Cox, Jahannaz Dastgir, Elizabeth T. DeChene, Rebecca Gooding, Heinz Jungbluth, Nuria Muelas, Johanna Palmio, Sini Penttilä, Eric Schmedding, Tiina Suominen, Volker Straub, Christopher Staples, Peter Van den Bergh, Juan J. Vílchez, Kathryn R. Wagner, Patricia G. Wheeler, Elizabeth Wraige, Agnete Fossbakk, Rune Kleppe, Per M. Knappskog, Aurora Martı́nez, Jan Haavik, Meng-Chang Hsiao, Arkadiusz Piotrowski, John Alexander, Tom Callens, Chuanhua Fu, Fady M. Mikhail, Kathleen Claes, Ludwine Messiaen, Renjie Tan, Sarah E. Kleinstein, Yongzhuang Liu, Xiaolin Zhu, Hongzhe Guo, Qinghua Jiang, Andrew J. Allen, Mingfu Zhu,
Human MutationVolume 35, Issue 7 p. i-iii ContentFree Access Contents First published: 10 June 2014 https://doi.org/10.1002/humu.22598AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a ...
Tópico(s): Nutrition, Genetics, and Disease
2014 - Wiley | Human Mutation