Seung‐Nam Jung, Woo Kyeom Yang, Joungmok Kim, Hak Su Kim, Eun Ju Kim, Hee Yun, Hyunsung Park, Sung Soo Kim, Wonchae Choe, Insug Kang, Joohun Ha,
... conditions, such as cancer. Although reactive oxygen species (ROS) have been implicated in the regulation of hypoxic ... HIF-1 under various conditions, the role of ROS is quite controversial, and the mechanism underlying the HIF-1 regulation by ROS is not completely understood yet. Here, we investigated the biochemical mechanism for the ROS-induced HIF-1 by revealing a novel role ... adenosine triphosphate-deprived conditions. Here we report that ROS induced by a direct application of H 2 ... inhibition of AMPK enhances HIF-1α ubiquitination under ROS condition. Finally, we show that the regulation of ...
Tópico(s): Adipose Tissue and Metabolism
2008 - Oxford University Press | Carcinogenesis
Hak‐Su Kim, Hyun Ju Yoo, Kwang Min Lee, Ha Eun Song, Su Jung Kim, Jae Ok Lee, Jung Jin Hwang, Jin Woo Song,
... decreased the levels of p‐Smad2/3 and ROS in MRC‐5 cells treated with TGF‐β1 ...
Tópico(s): Eosinophilic Disorders and Syndromes
2020 - Wiley | Respirology