Produção Nacional
Revisado por pares
Elisabete M. Assaf, Roberto C. Giordano, Cláudio Augusto Oller do Nascimento,
The dynamic behavior of an ethylene oxidation fixed-bed reactor has been originally simulated by a phenomenological model, encompassing mass and energy balances of the catalytic bed. This model makes use of the one-dimensional pseudo-homogeneous approach, with apparent kinetic parameters obtained from the literature. The resulting set of partial-differential equations is solved by discretization of the space variable in finite-differences and integration of the attained ordinary-differential equations ...
Tópico(s): Model Reduction and Neural Networks
1996 - Elsevier BV | Chemical Engineering Science
Produção Nacional
Revisado por pares
Vitor Carlos Coletta, Renato V. Gonçalves, Maria Inês Basso Bernardi, Dorian A. H. Hanaor, M. Hussein N. Assadi, Francielle Candian Firmino Marcos, Francisco G.E. Nogueira, Elisabete M. Assaf, Valmor Roberto Mastelaro,
The water gas shift reaction (WGS) is important and widely applied in the production of H2. Cu modified perovskites are promising catalysts for WGS reactions in hydrogen generation. However, the structure-dependent stability and reaction pathways of such materials remain unclear. Herein, we report catalytically active Cu modified SrTiO3 (nominally SrTi1-xCuxO3) prepared by a modified polymeric precursor method. Microstructural analysis revealed a partially segregated CuO phase in the as-prepared materials. ...
Tópico(s): Copper-based nanomaterials and applications
2020 - American Chemical Society | ACS Applied Energy Materials
Vitor Carlos Coletta, Francielle Candian Firmino Marcos, Francisco G.E. Nogueira, Maria Inês Basso Bernardi, Alain Michalowicz, Renato V. Gonçalves, Elisabete M. Assaf, Valmor Roberto Mastelaro,
Perovskite strontium titanate is a promising functional material for gas sensors and catalysis applications. Herein, we report the preparation of SrTi1-xCuxO3 nanoparticles with Cu doped in the B sites using a modified polymeric precursor method. This study describes in detail the structural and local atomic configurations for the substitution of Cu into the titanium sites and its reducibility using X-ray diffraction (XRD), field emission gun scanning and transmission electron microscopies (FEG-SEM ...
Tópico(s): ZnO doping and properties
2015 - Royal Society of Chemistry | Physical Chemistry Chemical Physics
Amira Assaf, Roberto Diletti, Mark G. Hoogendijk, Marisa van der Graaf, Felix Zijlstra, Tamás Szili-Török, Sing‐Chien Yap,
Introduction The presence of a chronic total occlusion (CTO) is associated with an increased risk of ventricular arrhythmias.Areas covered This review provides an overview of the relationship between CTO and ventricular arrhythmias, arrhythmogenic mechanisms, and the effect of revascularization.Expert opinion Studies in recipients of an implantable cardioverter-defibrillator (ICD) have shown that a CTO is an independent predictor of appropriate ICD therapy. The myocardial territory supplied by a CTO ...
Tópico(s): Cardiac Arrhythmias and Treatments
2020 - Taylor & Francis | Expert Review of Cardiovascular Therapy
Assaf Ben-Shoham, Roberto Serrano, Oscar Volij,
Tópico(s): Game Theory and Voting Systems
2003 - Elsevier BV | Journal of Economic Theory
Marco Maccaferri, Neil S. Harris, Sven Twardziok, Raj Pasam, Heidrun Gundlach, M. Spannagl, Danara Ormanbekova, Thomas Lux, Verena M. Prade, Sara G. Milner, Axel Himmelbach, Martin Mascher, Paolo Bagnaresi, Primetta Faccioli, Paolo Cozzi, Massimiliano Lauria, Barbara Lazzari, Alessandra Stella, Andrea Manconi, Matteo Gnocchi, Marco Moscatelli, Raz Avni, Jasline Deek, Sezgi Biyiklioglu, Elisabetta Frascaroli, Simona Corneti, Silvio Salvi, Gabriella Sonnante, Francesca Desiderio, Caterina Marè, Cristina Crosatti, E. Mica, Hakan Özkan, Benjamin Kilian, Pasquale De Vita, Daniela Marone, Reem Joukhadar, Elisabetta Mazzucotelli, Domenica Nigro, Ágata Gadaleta, Shiaoman Chao, Justin D. Faris, Arthur Melo, Michael Pumphrey, Nicola Pecchioni, Luciano Milanesi, Krystalee Wiebe, Jennifer Ens, Ron MacLachlan, J. M. Clarke, Andrew Sharpe, ChuShin Koh, Kevin Y. H. Liang, Gregory J. Taylor, R. E. Knox, Hikmet Budak, Anna Maria Mastrangelo, Steven S. Xu, Nils Stein, Iago Hale, Assaf Distelfeld, Matthew Hayden, Roberto Tuberosa, Sean Walkowiak, Klaus Mayer, Aldo Ceriotti, Curtis Pozniak, Luigi Cattivelli,
The domestication of wild emmer wheat led to the selection of modern durum wheat, grown mainly for pasta production. We describe the 10.45 gigabase (Gb) assembly of the genome of durum wheat cultivar Svevo. The assembly enabled genome-wide genetic diversity analyses revealing the changes imposed by thousands of years of empirical selection and breeding. Regions exhibiting strong signatures of genetic divergence associated with domestication and breeding were widespread in the genome with several ...
Tópico(s): Bioenergy crop production and management
2019 - Nature Portfolio | Nature Genetics
Yoav Lahini, Assaf Avidan, Francesca Pozzi, Marc Sorel, Roberto Morandotti, Demetrios N. Christodoulides, Yaron Silberberg,
We experimentally investigate the evolution of linear and nonlinear waves in a realization of the Anderson model using disordered one dimensional waveguide lattices. Two types of localized eigenmodes, flat-phased and staggered, are directly measured. Nonlinear perturbations enhances localization in one type, and induce delocalization in the other. In a complementary approach, we study the evolution on short time scales of $\delta$-like wavepackets in the presence of disorder. A transition from ballistic ...
Tópico(s): Advanced Fiber Laser Technologies
2008 - American Physical Society | Physical Review Letters
Roberto G. Carbone, Assaf Monselise, G Bottino, Simone Negrini, Francesco Puppo,
Abstract Stem cells transplantation after acute myocardial infarction (AMI) has been claimed to restore cardiac function. However, this therapy is still restricted to experimental studies and clinical trials. Early un-blinded studies suggested a benefit from stem cell therapy following AMI. More recent blinded randomized trials have produced mixed results and, notably, the last largest pan-European clinical trial showed the inconclusive results. Furthermore, mechanisms of potential benefit remain ...
Tópico(s): Pluripotent Stem Cells Research
2021 - Springer Science+Business Media | Clinical and Experimental Medicine
Produção Nacional
Revisado por pares
Ananda Vallezi Paladino Lino, Yormary Nathaly Colmenares Calderon, Valmor Roberto Mastelaro, Elisabete M. Assaf, José Mansur Assaf,
Nickel catalysts supported on magnesium aluminate promoted with ZrO2, CeZrO2 and CeO2 were evaluated under methane tri-reforming reaction. MgAl2O4 synthesis was assisted by P123® surfactant, assuring high porosity. The catalysts were tested at 650 °C and 750 °C. Zr and CeZr promoted catalysts showed less coke deposition and increased conversions, mainly at 750 °C, while the non-promoted catalyst featured lowest reactants conversion due to an unstable performance caused by filamentous coke deposition. ...
Tópico(s): Catalysis and Hydrodesulfurization Studies
2019 - Elsevier BV | Applied Surface Science
Produção Nacional
Revisado por pares
Cristhiane Reis, Tatiana de Freitas Silva, Luciene Paula Roberto Profeti, Elisabete M. Assaf, José Mansur Assaf,
The CuO/CeO2 system was investigated as a catalyst for preferential CO oxidation reaction in hydrogen-rich feed (PROX-CO). The catalysts were prepared by deposition–precipitation (DEP) and co-precipitation (COP) methods and the catalytic performance reveals that the preparation method influences the properties of solids prepared, where a direct consequence is the difference in behavior of the catalysts in the PROX-CO reaction. A high specific area and a better dispersion of the metallic phase were ...
Tópico(s): Catalysts for Methane Reforming
2012 - Elsevier BV | Applied Catalysis A General
Produção Nacional
Revisado por pares
Cristhiane Reis, Luciene Paula Roberto Profeti, Elisabete M. Assaf, José Mansur Assaf,
CuO/CeO2, CuO/Al2O3 and CuO/CeO2–Al2O3 catalysts, with CuO loading varying from 1 to 5 wt.%, were prepared by the citrate method and applied to the preferential oxidation of carbon monoxide in a reaction medium containing large amounts of hydrogen (PROX-CO). The compounds were characterized ex situ by X-ray diffraction, specific surface area measurements, temperature-programmed reduction and temperature-programmed reduction of oxidized surfaces; XANES-PROX in situ experiments were also carried out ...
Tópico(s): Catalysts for Methane Reforming
2010 - Elsevier BV | Journal of Power Sources
Produção Nacional
Revisado por pares
Davi D. Petrolini, Francielle Candian Firmino Marcos, Alessandra Fonseca Lucrédio, Valmor Roberto Mastelaro, José Mansur Assaf, Elisabete M. Assaf,
The oxidative coupling of methane reaction to produce C 2 compounds was studied using La 2 (Ce 1−x Mg x ) 2 O 7−δ catalysts with disordered defective cubic fluorite structures, varying the Mg content (0.0 ≤ x ≤ 1.0), CH 4 /O 2 ratio, temperature, and WHSV.
Tópico(s): Advanced Condensed Matter Physics
2021 - Royal Society of Chemistry | Catalysis Science & Technology
Gad Weiss, Dimitry Kovalerchick, Judy Lieman‐Hurwitz, Omer Murik, Roberto De Philippis, Shmuel Carmeli, Assaf Sukenik, Aaron Kaplan,
Summary Toxic Microcystis spp. blooms constitute a serious threat to water quality worldwide. Aeromonas veronii was isolated from Microcystis sp. colonies collected in Lake Kinneret. Spent Aeromonas media inhibits the growth of Microcystis aeruginosa MGK isolated from Lake Kinneret. The inhibition was much stronger when Aeromonas growth medium contained spent media from MGK suggesting that Aeromonas recognized its presence and produced secondary metabolites that inhibit Microcystis growth. Fractionations ...
Tópico(s): Marine Invertebrate Physiology and Ecology
2019 - Wiley | Environmental Microbiology
Roberto Molinaro, Jonathan O. Martinez, Assaf Zinger, Alessandro De Vita, Gianluca Storci, Noemi Arrighetti, Enrica De Rosa, Kelly A. Hartman, Nupur Basu, Nima Taghipour, Claudia Corbo, Ennio Tasciotti,
In the last decades, several approaches were developed to design drug delivery systems to address the multiple biological barriers encountered after administration while safely delivering a payload. In this scenario, bio-inspired and bio-mimetic approaches have emerged as promising solutions to evade the mononuclear phagocytic system while simultaneously negotiating the sequential transport across the various biological barriers. Leukocytes freely circulate in the bloodstream and selectively target ...
Tópico(s): Extracellular vesicles in disease
2019 - Royal Society of Chemistry | Biomaterials Science
Ana Belén Rodríguez, R. Bodas, Roberto Landa, Ó. López-Campos, Ángel R. Mantecón, Francisco Javier Giráldez,
This study was conducted to compare the growth, carcass and meat quality of light, intensively reared Assaf and crossbred Merino × Assaf lambs. Twelve Assaf and 12 Merino × Assaf lambs of both sexes were intensively reared from weaning until they reached 20 kg live body weight (LBW). Crossbreeding improved both daily weight gain (P < 0.01) and feed conversion (P < 0.001), resulting in a reduction in accumulative dry matter consumption (P < 0.05). Carcass conformation was also improved by crossbreeding, although ...
Tópico(s): Rabbits: Nutrition, Reproduction, Health
2010 - Elsevier BV | Livestock Science
Ana Belén Rodríguez, R. Bodas, N. Prieto, Roberto Landa, Ángel R. Mantecón, Francisco Javier Giráldez,
The effect of feeding system and sex on intake, growth and carcass and meat characteristics of Assaf fattening lambs was studied. Twenty four weaned Assaf lambs, half males and half females were used. After an adaptation period, lambs were randomly assigned to one of the two feeding systems studied. Control lambs received ad libitum commercial concentrate (70% barley, 22% soybean meal, 4.8% wheat, 0.5% bicarbonate, 2.7% mineral–vitamin premix) and barley straw. Free Choice lambs had ad libitum and ...
Tópico(s): Rabbits: Nutrition, Reproduction, Health
2007 - Elsevier BV | Livestock Science
Produção Nacional
Revisado por pares
Luciene Paula Roberto Profeti, Edson A. Ticianelli, Elisabete M. Assaf,
The performance of noble metal (Pt, Ru, Ir)-promoted Co/MgAl2O4 catalysts for the steam reforming of ethanol was investigated. The catalysts were characterized by energy-dispersive X-ray spectroscopy, X-ray diffraction, UV–vis diffuse reflectance spectroscopy, temperature-programmed reduction, temperature-programmed oxidation and X-ray absorption near edge structure (XANES). The results showed that the formation of inactive cobalt aluminate was suppressed by the presence of a MgAl2O4 spinel phase. ...
Tópico(s): Catalysis and Hydrodesulfurization Studies
2009 - Elsevier BV | Applied Catalysis A General
Produção Nacional
Revisado por pares
Luciene Paula Roberto Profeti, Edson A. Ticianelli, Elisabete M. Assaf,
The catalytic activity of Ni/CeO2–Al2O3 catalysts modified with noble metals (Pt, Ir, Pd and Ru) was investigated for the steam reform of ethanol and glycerol. The catalysts were characterized by the following techniques: Energy-dispersive X-ray, BET, X-ray diffraction, temperature-programmed reduction, UV–vis diffuse reflectance spectroscopy and X-ray absorption near edge structure (XANES). The results showed that the formation of inactive nickel aluminate was prevented by the presence of CeO2 dispersed ...
Tópico(s): Catalysis for Biomass Conversion
2009 - Elsevier BV | International Journal of Hydrogen Energy
Produção Nacional
Revisado por pares
Luciene Paula Roberto Profeti, Edson A. Ticianelli, Elisabete M. Assaf,
The catalytic performance of Co/Al2O3 catalysts promoted with small amounts noble metals (Pt, Pd, Ru, Ir) for steam reforming of ethanol (SRE) has been investigated. The catalysts were characterized by the energy dispersive X-ray, X-ray diffraction, BET surface area, X-ray absorption fine structure and temperature reduction programmed techniques. The results showed that the promoting effect of noble metals included a marked decrease of the reduction temperatures of both Co3O4 and cobalt surface species ...
Tópico(s): Catalysis and Hydrodesulfurization Studies
2007 - Elsevier BV | Journal of Power Sources
Produção Nacional
Revisado por pares
Luciene Paula Roberto Profeti, Edson A. Ticianelli, Elisabete M. Assaf,
The effect of noble metal addition on the catalytic properties of Co/Al2O3 was evaluated for the steam reforming of methane. Co/Al2O3 catalysts were prepared with addition of different noble metals (Pt, Pd, Ru and Ir 0.3 wt.%) by a wetness impregnation method and characterized by UV–vis spectroscopy, temperature programmed reduction (TPR) and temperature programmed oxidation (TPO) of the reduced catalysts. The UV–vis spectra of the samples indicate that, most likely, large amounts of the supported ...
Tópico(s): Catalysis and Oxidation Reactions
2007 - Elsevier BV | Fuel
Ana Belén Rodríguez, Roberto Landa, R. Bodas, N. Prieto, Ángel R. Mantecón, Francisco Javier Giráldez,
The effect of sex and rearing system on growth and carcass and meat characteristics of milk fed Assaf lambs was studied. Thirty-six lambs, 18 males and 18 females were used. Twelve lambs remained with their mothers throughout the experiment (NR). Within 24-36h of birth, the rest were housed individually and fed twice a day ad libitum (AAR) or at 70% of ad libitum consumption (RAR) with reconstituted cow's milk. Sex did not affect animal performance, yet females showed higher carcass and non-carcass ...
Tópico(s): Genetic and phenotypic traits in livestock
2007 - Elsevier BV | Meat Science
Thomas Look, Emanuele Puca, Marcel Bühler, Daniel S. Kirschenbaum, Roberto De Luca, Riccardo Stucchi, Domenico Ravazza, Cesare Di Nitto, Patrick Roth, Yonatan Katzenelenbogen, Assaf Weiner, Lukas Rindlisbacher, Burkhard Becher, Ido Amit, Michael Weller, Dario Neri, Teresa Hemmerle, Tobias Weiß,
Glioblastoma is the most aggressive primary brain tumor with an unmet need for more effective therapies. Here, we investigated combination therapies based on L19TNF, an antibody-cytokine fusion protein based on tumor necrosis factor that selectively localizes to cancer neovasculature. Using immunocompetent orthotopic glioma mouse models, we identified strong anti-glioma activity of L19TNF in combination with the alkylating agent CCNU, which cured the majority of tumor-bearing mice, whereas monotherapies ...
Tópico(s): Advanced biosensing and bioanalysis techniques
2023 - American Association for the Advancement of Science | Science Translational Medicine
Produção Nacional
Revisado por pares
Luciene Paula Roberto Profeti, Joelmir Augusto Costa Dias, José Mansur Assaf, Elisabete M. Assaf,
The catalytic activity of Ni/La2O3-Al2O3 catalysts modified with noble metals (Pt and Pd) was investigated in the steam reforming of ethanol. The catalysts were characterized by ICP, SBET, X-ray diffraction, temperature-programmed reduction, UV–vis diffuse reflectance spectroscopy and X-ray absorption fine structure (XANES). The results showed that the formation of inactive nickel aluminate was prevented by the presence of La2O3 dispersed on the alumina. The promoting effect of noble metals included ...
Tópico(s): Catalysis and Hydrodesulfurization Studies
2009 - Elsevier BV | Journal of Power Sources
Christian Boada, Assaf Zinger, Christopher Tsao, Picheng Zhao, Jonathan O. Martinez, Kelly A. Hartman, Tomoyuki Naoi, Roman Sukhovershin, Manuela Sushnitha, Roberto Molinaro, Barry Trachtenberg, John P. Cooke, Ennio Tasciotti,
Through localized delivery of rapamycin via a biomimetic drug delivery system, it is possible to reduce vascular inflammation and thus the progression of vascular disease.Use biomimetic nanoparticles to deliver rapamycin to the vessel wall to reduce inflammation in an in vivo model of atherosclerosis after a short dosing schedule.Biomimetic nanoparticles (leukosomes) were synthesized using membrane proteins purified from activated J774 macrophages. Rapamycin-loaded nanoparticles were characterized ...
Tópico(s): Lipoproteins and Cardiovascular Health
2019 - Lippincott Williams & Wilkins | Circulation Research
Produção Nacional
Revisado por pares
Francielle Candian Firmino Marcos, Maria J. F. Costa, Gabriel L. Catuzo, Daniel A. Moraes, Marcos de Oliveira, Valmor Roberto Mastelaro, José Mansur Assaf, Reinaldo Giudici, Elisabete M. Assaf,
The xCu/MOF catalysts were synthesized by incipient-wetness impregnation of copper precursor on UiO-66 support, in which the Cu loadings were 5, 10, and 20% (wt.%). To gain insight into the properties of the materials, a range of techniques, including XRD, TEM, TGA, N2 physisorption, CO2-TPD, EDS, N2O chemisorption, XPS, IR, and NMR, were employed. The effectiveness of catalysts was evaluated for synthesizing methanol through CO2 hydrogenation under various Gas Hourly Space Velocities (GHSVs) and ...
Tópico(s): Catalytic Processes in Materials Science
2023 - Elsevier BV | Journal of Catalysis
Christian Boada, Assaf Zinger, Scott Rohen, Jonathan O. Martinez, Michael Evangelopoulos, Roberto Molinaro, Madeleine Lu, Ramiro Alejandro Villarreal-Leal, Federica Giordano, Manuela Sushnitha, Enrica De Rosa, Jens B. Simonsen, Sergey S. Shevkoplyas, Francesca Taraballi, Ennio Tasciotti,
Apolipoprotein-based drug delivery is a promising approach to develop safe nanoparticles capable of targeted drug delivery for various diseases. In this work, we have synthesized a lipid-based nanoparticle (NPs) that we have called "Aposomes" presenting native apolipoprotein B-100 (apoB-100), the primary protein present in Low-Density Lipoproteins (LDL) on its surface. The aposomes were synthesized from LDL isolated from blood plasma using a microfluidic approach. The synthesized aposomes had a diameter ...
Tópico(s): Systemic Lupus Erythematosus Research
2021 - Frontiers Media | Frontiers in Bioengineering and Biotechnology
Enrico Bonatti, R. Clocchiatti, P. Colantoni, Roberta Gelmini, G. Marinelli, G. Ottonello, Roberto Santacroce, Marco Taviani, A. A. Abdel-Meguid, H.S. Assaf, M. A. El Tahir,
Zabargad is a small island located in the Red Sea about 50 km W of its axis, between 23º and 24ºN. The island is not volcanic but probably represents an uplifted block of upper mantle and crustal rocks, and yields information on the nature of the underlying lithosphere. Peridotites are the main rock type, consisting of exceptionally fresh spinel lherzolites, which equilibrated last at a depth >30 km in the mantle. Other ultramafic facies, some representing rocks which mixed with a basaltic melt fraction, ...
Tópico(s): High-pressure geophysics and materials
1983 - Geological Society of London | Journal of the Geological Society
Produção Nacional
Revisado por pares
Sérgio Roberto de Souza Leão da Costa Campos, Thatiana Corrêa de Melo, S. Assaf, Rodrigo Pinheiro Araldi, J. Mazzuchelli-de-Souza, Marcelo Palma Sircili, Rodrigo Franco de Carvalho, Franco Roperto, Willy Beçak, Rita de Cássia Stocco,
THE MAJORITY OF MALIGNANT CELLS PRESENT GENETIC INSTABILITY WITH CHROMOSOME NUMBER CHANGES PLUS SEGMENTAL DEFECTS: these changes involve intact chromosomes and breakage-induced alterations. Some pathways of chromosomal instability have been proposed as random breakage, telomere fusion, and centromere fission. Chromosome alterations in tumor cells have been described in animal models and in vitro experiments. One important question is about possible discrepancies between animal models, in vitro studies, ...
Tópico(s): Virus-based gene therapy research
2013 - Hindawi Publishing Corporation | ISRN Oncology
Marco Maccaferri, Andrea Ricci, Silvio Salvi, Sara G. Milner, Enrico Noli, Pier Luigi Martelli, Rita Casadio, Eduard Akhunov, Simone Scalabrin, Vera Vendramin, Karim Ammar, Antonio Blanco, Francesca Desiderio, Assaf Distelfeld, Jorge Dubcovsky, Tzion Fahima, Justin D. Faris, Abraham B. Korol, A. Massi, Anna Maria Mastrangelo, Michele Morgante, Curtis Pozniak, Amidou N’Diaye, Steven S. Xu, Roberto Tuberosa,
Summary Consensus linkage maps are important tools in crop genomics. We have assembled a high‐density tetraploid wheat consensus map by integrating 13 data sets from independent biparental populations involving durum wheat cultivars ( Triticum turgidum ssp. durum ), cultivated emmer ( T. turgidum ssp . dicoccum ) and their ancestor (wild emmer, T. turgidum ssp. dicoccoides ). The consensus map harboured 30 144 markers (including 26 626 SNPs and 791 SSRs) half of which were present in at least two component maps. ...
Tópico(s): Genetics and Plant Breeding
2014 - Wiley | Plant Biotechnology Journal
Roberto Avolio, Schiavone, Portesi, Abete, Squadrone,
ABSTR ACT medical purposes intended for infants and young children and young child formulae marketed as liquid) to 0.50 mg/kg -1 (drinks for infants and young children labeled and sold as such, to be prepared by infusion or decoction).No sample exceeded the ML, 31% of samples had detectable levels of Pb and a mean value of 0.011 mg/kg -1 . Conclusions:Infants and toddlers are particularly vulnerable to metals than adults, since neurotoxic effects are particularly dangerous in developing organisms; moreover, ...
Tópico(s): Helminth infection and control
2023 - Wiley | Journal of Veterinary Pharmacology and Therapeutics