Tomas Sinnige, Biagio Della Corte, Reynard de Vries, Francesco Avallone, Roberto Merino-Martínez, Daniele Ragni, G. Eitelberg, Leo L. Veldhuis,
The impingement of a propeller slipstream on a downstream surface causes unsteady loading, which may lead to vibrations responsible for structure-borne noise. A low-speed wind-tunnel experiment was performed to quantify the potential of a flow-permeable leading edge to alleviate the slipstream-induced unsteady loading. For this purpose, a tractor propeller was installed at the tip of a pylon featuring a replaceable leading-edge insert in the region of slipstream impingement. Tests were carried out ...
Tópico(s): Vibration and Dynamic Analysis
2019 - American Institute of Aeronautics and Astronautics | Journal of Aircraft
Alessandro Amato, A. Avallone, Roberto Basili, Fabrizio Bernardi, Beatriz Brizuela, Laura Graziani, A. Herrero, Maria Concetta Lorenzino, Stefano Lorito, F. Mele, Alberto Michelini, A. Piatanesi, Stefano Pintore, Fabrizio Romano, Jacopo Selva, Salvatore Stramondo, Roberto Tonini, Manuela Volpe,
Abstract The Italian Tsunami Alert Center based at the Istituto Nazionale di Geofisica e Vulcanologia (CAT-INGV) has been monitoring the Mediterranean seismicity in the past 8 yr to get fast and reliable information for seismically induced tsunami warnings. CAT-INGV is a tsunami service provider in charge of monitoring the seismicity of the Mediterranean Sea and of alerting Intergovernmental Oceanographic Commission (IOC)/UNESCO subscriber Member States and the Italian Department of Civil Protection ...
Tópico(s): Earthquake Detection and Analysis
2021 - Seismological Society of America | Seismological Research Letters
Giovanni Di Stasi, Jonas Karlsson, Stefano Avallone, Roberto Canonico, Andreas Kassler, Anna Brunström,
Wireless mesh networks (WMNs) based on the IEEE 802.11 standard are becoming increasingly popular as a viable alternative to wired networks. WMNs can cover large or difficult to reach areas with low deployment and management costs. Several multi-path routing algorithms have been proposed for such kind of networks with the objective of load balancing the traffic across the network and providing robustness against node or link failures. Packet aggregation has also been proposed to reduce the overhead ...
Tópico(s): Cooperative Communication and Network Coding
2014 - Elsevier BV | Computer Networks
Tommaso Bellini, Francesco Mantegazza, Vittorio Degiorgio, Roberto Avallone, D. A. Saville,
Frequency-resolved electric birefringence experiments are carried out on dilute colloidal suspensions of charged, rodlike particles over a wide frequency range. The Kerr constant displays new relaxation features impossible to identify with dielectric spectroscopy. Our data provide the first explicit evidence of Maxwell-Wagner relaxation of the electric polarizability of charged colloids. We successfully explain the observed behavior with a model combining electrokinetic and Maxwell-Wagner approaches. ...
Tópico(s): Microfluidic and Bio-sensing Technologies
1999 - American Physical Society | Physical Review Letters
Alessandro Parisi, Giampiero Porzio, Katia Cannita, Olga Venditti, Antonio Avallone, Roberto Filippi, Lisa Salvatore, Giampaolo Tortora, Marta Ribelli, Olga Nigro, Fabio Gelsomino, Andrea Spallanzani, Ina Valeria Zurlo, Silvana Leo, Emanuela Dell’Aquila, Claudia Angela Maria Fulgenzi, Pasquale Lombardi, Susana Roselló, Giacomo Aimar, Ilaria Depetris, Riccardo Giampieri, Maria Cristina Morelli, Michele De Tursi, Nicola Tinari, Francesca Romana Di Pietro, Federica De Galitiis, N. Zanaletti, Teresa Troiani, Pasquale Vitale, Ingrid Garajová, Michele Ghidini, Gian Paolo Spinelli, Federica Zoratto, Michela Roberto, Debora Ierinò, Angelica Petrillo, C. D’Orazio, Corrado Ficorella, Alessio Cortellini,
Background Doublets plus antiepidermal growth factor receptors monoclonal antibodies (EGFRi) are widely considered the preferable first-line regimen in patients with left-sided RAS/BRAF wild-type metastatic colorectal cancer (mCRC), resulting superior in terms of activity and efficacy compared to doublets plus bevacizumab. However, data comparing doublet plus EGFRi and triplet plus bevacizumab are lacking, and the relative benefit of an intensive regimen plus an antiangiogenic backbone in this population ...
Tópico(s): Genetic factors in colorectal cancer
2021 - Elsevier BV | Clinical Colorectal Cancer
Angelo Campanozzi, S. Avallone, Antonio Barbato, Roberto Iacone, Ornella Russo, Gianpaolo De Filippo, G D'Angelo, Licia Pensabene, Basilio Malamisura, Gaetano Cecere, Maria Micillo, Ruggiero Francavilla, A. Marc Tetro, Giuliano Lombardi, L Tonelli, G. Castellucci, Luigi Ferraro, Rita Di Biase, Antonella Lezo, Silvia Salvatore, Silvia Paoletti, Alfonso Siani, Daniela Galeone, Pasquale Strazzullo,
Hypertension is the leading cause of death in developed countries and reduction of salt intake is recommended as a key preventive measure.To assess the dietary sodium and potassium intakes in a national sample of Italian children and adolescents and to examine their relationships with BMI and blood pressure (BP) in the framework of the MINISAL survey, a program supported by the Italian Ministry of Health.The study population included 1424 healthy subjects (766 boys, 658 girls) aged 6-18 years (mean ...
Tópico(s): Blood Pressure and Hypertension Studies
2015 - Public Library of Science | PLoS ONE
Fotios Loupakis, Rossana Intini, Chiara Cremolini, Armando Orlandi, Andrea Sartore‐Bianchi, Filippo Pietrantonio, Nicoletta Pella, Andrea Spallanzani, Emanuela Dell’Aquila, Mario Scartozzi, Emmanuele De Luca, Lorenza Rimassa, Vincenzo Formica, Francesco Leone, Lorenzo Calvetti, Giuseppe Aprile, Lorenzo Antonuzzo, Federica Urbano, Hans Prenen, Francesca Negri, Samantha Di Donato, Pasquale Buonandi, Gianluca Tomasello, Antonio Avallone, Fable Zustovich, Roberto Moretto, Carlotta Antoniotti, Lisa Salvatore, Maria Alessandra Calegari, Salvatore Siena, Federica Morano, Elena Ongaro, Stefano Cascinu, Daniele Santini, Pina Ziranu, Marta Schirripa, Federica Buggin, Alessandra Anna Prete, Ilaria Depetris, Paola Biason, Sara Lonardi, Vittorina Zagonel, Matteo Fassan, Massimo Di Maïo,
Background Despite the well-known negative prognostic value of the V600EBRAF mutation in patients with metastatic colorectal cancer (mCRC), its outcome is quite heterogeneous, and the basis for this prognostic heterogeneity should be better defined. Methods Two large retrospective series of V600EBRAF-mutated mCRC from 22 institutions served as an exploratory and validation set to develop a prognostic score. The model was internally and externally validated. Results A total of 395 V600EBRAF-mutated ...
Tópico(s): Lung Cancer Treatments and Mutations
2019 - Elsevier BV | European Journal of Cancer
Sara Damiano, Maria Valeria Puzio, Caterina Squillacioti, Nicola Mirabella, Enrica Zona, Aldo Mancini, Antonella Borrelli, Carlo Astarita, Silvia Boffo, Antonio Giordano, Luigi Avallone, Salvatore Florio, Roberto Ciarcia,
ABSTRACT Ochratoxin A (OTA) is a mycotoxin produced by Aspergillus and Penicillium that represent toxic real threat for human beings and animal health. In this study we evaluated the effect of a new recombinant mitochondrial manganese containing superoxide dismutase (rMnSOD) on oxidative stress and on the alterations of fluid reabsorption in renal proximal tubule (PT) as possible causes of OTA nephrotoxicity. Finally, we have measured the concentration of O 2 − in the kidney through dihydroethidium assay ( ...
Tópico(s): Mycotoxins in Agriculture and Food
2017 - Wiley | Journal of Cellular Biochemistry
Alejandro Rubio Carpio, Roberto Merino-Martínez, Francesco Avallone, Daniele Ragni, Mirjam Snellen, Sybrand van der Zwaag,
The hydrodynamic and acoustic fields for a NACA 0018 with solid and porous trailing edge inserts are investigated. The porous inserts, covering 20% of the chord, are manufactured with metal foams with cell diameters of 450 and 800 μm and permeability values of 6 × 10−10 and 2.7 × 10−9 m2. The experiments are performed at a chord-based Reynolds number of 2.63 × 105 and an angle of attack of 0°. The porous trailing edge with higher permeability provides up to 11 dB noise attenuation with respect to the ...
Tópico(s): Wind and Air Flow Studies
2018 - Elsevier BV | Journal of Sound and Vibration
Vincenza Granata, Roberta Fusco, Orlando Catalano, Salvatore Filice, Antonio Avallone, Mauro Piccirillo, Maddalena Leongito, Raffaéle Palaia, Roberto Grassi, Francesco Izzo, Antonella Petrillo,
To report our cancer centre experience in the biliary tumours incidence other than cholangiocellular-carcinoma, emphasizing the radiological features.197 patients with biliary disease undergoing Gd-EOB-DTPA-enhanced MRI were reviewed. Four radiologists evaluated retrospectively size, structure, anatomical site and signal intensity of lesions on MRI. Enhancement-pattern during the arterial-, portal- and late-phase on ultrasound, CT and MR study was assessed as well as the enhancement pattern during ...
Tópico(s): Genetic and Kidney Cyst Diseases
2017 - Wiley | British Journal of Radiology
Teresa Troiani, Erika Martinelli, Davide Ciardiello, N. Zanaletti, Claudia Cardone, C. Borrelli, Antonio Avallone, Alfredo Falcone, Evaristo Maiello, Roberto Bordonaro, Daniele Santini, Carlo Garufi, Filippo de Braud, Carmine Pinto, Cesare Gridelli, Fortunato Ciardiello,
TPS731 Background: The immune system plays a crucial role in modulating response to monoclonal antibodies therapy in cancer. Novel immunecheckpoint inhibitors have demonstrated potent efficacy alone and in combinations with cytotoxic agents in several cancers. In this regard, avelumab in combination with cetuximab might be a relevant rechallenge strategy in RAS wild-type (WT) metastatic colorectal cancer (mCRC) patients treated in first-line with chemotherapy (CT) in combination with anti-EGFR drugs ...
Tópico(s): Lung Cancer Treatments and Mutations
2019 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
Pietro Cortelli, Rossella Avallone, Mario Baraldi, Maria Luisa Zeneroli, Jessica Mandrioli, Lorenzo Corsi, Roberto Riva, Paolo Tinuper, E Lugaresi, Agostino Baruzzi, Pasquale Montagna,
Stupor is a condition from which the subject can be aroused only by vigorous stimuli. Most patients with stupor have a diffuse organic cerebral dysfunction. Rarely stupor is recurrent and no specific causes can be found. Patients with idiopathic recurrent stupor were awakened by i.v. administration of an antagonist (flumazenil) of the benzodiazepine recognition site located in the GABA(A) receptor. Since no exogenous benzodiazepines were detected in plasma and cerebrospinal fluid by high performance ...
Tópico(s): Pelvic floor disorders treatments
2005 - Elsevier BV | Sleep Medicine Reviews
V. Fanotto, Elena Ongaro, Karim Rihawi, Antonio Avallone, Nicola Silvestris, Lorenzo Fornaro, Enrico Vasile, Lorenzo Antonuzzo, Francesco Leone, Gerardo Rosati, Francesco Giuliani, Roberto Bordonaro, Mario Scartozzi, Giovanna De Maglio, Francesca Negri, Gianpiero Fasola, Giuseppe Aprile,
... 1,* , Elena Ongaro 1,* , Karim Rihawi 2 , Antonio Avallone 3 , Nicola Silvestris 4 , Lorenzo Fornaro 5 , Enrico Vasile 5 , Lorenzo Antonuzzo 6 , Francesco Leone 7 , Gerardo Rosati 8 , Francesco Giuliani 4 , Roberto Bordonaro 9 , Mario Scartozzi 10 , Giovanna De Maglio ...
Tópico(s): Monoclonal and Polyclonal Antibodies Research
2016 - Impact Journals LLC | Oncotarget
Stefania Napolitano, Vincenzo De Falco, Giulia Martini, Davide Ciardiello, Erika Martinelli, Carminia Maria Della Corte, Lucia Esposito, Vincenzo Famiglietti, Alessandra Di Liello, Antonio Avallone, Claudia Cardone, Alfonso De Stefano, Vincenzo Montesarchio, Maria Giulia Zampino, Roberto Bordonaro, Mario Scartozzi, Daniele Santini, Massimo Di Maïo, Ferdinando De Vita, Lucia Altucci, Francesca Marrone, Fortunato Ciardiello, Teresa Troiani,
Importance Current third-line therapies for patients with metastatic colorectal cancer (MCRC) have limited efficacy. Rechallenge with epidermal growth factor receptor (EGFR) inhibitors for RAS wild-type (WT) MCRC may be valuable for these patients. Objective To compare the anti-EGFR monoclonal antibody panitumumab plus standard-of-care trifluridine-tipiracil with trifluridine-tipiracil alone as third-line therapy for RAS WT MCRC. Design, Setting, and Participants This phase 2 randomized clinical trial ( ...
Tópico(s): Cancer Genomics and Diagnostics
2023 - American Medical Association | JAMA Oncology
Vincenza Granata, Roberta Fusco, Maria Luisa Barretta, Carmine Picone, Antonio Avallone, Andrea Belli, Renato Patrone, Marilina Ferrante, Diletta Cozzi, Roberta Grassi, Roberto Grassi, Francesco Izzo, Antonella Petrillo,
Abstract Background Radiomics is an emerging field and has a keen interest, especially in the oncology field. The process of a radiomics study consists of lesion segmentation, feature extraction, consistency analysis of features, feature selection, and model building. Manual segmentation is one of the most critical parts of radiomics. It can be time-consuming and suffers from variability in tumor delineation, which leads to the reproducibility problem of calculating parameters and assessing spatial ...
Tópico(s): Gastric Cancer Management and Outcomes
2021 - BioMed Central | Infectious Agents and Cancer
Carlos Arce León, Roberto Merino-Martínez, Daniele Ragni, Francesco Avallone, Mirjam Snellen,
Trailing edge serrations designed to reduce airfoil self-noise are retrofitted on a NACA 0018 airfoil. An investigation of the boundary layer flow statistical properties is performed using time-resolved stereoscopic PIV. Three streamwise locations over the edge of the serrations are compared. An analysis of the results indicates that, while there is no upstream effect, the flow experiences significant changes as it convects over the serrations and toward its edges. Among the most important, a reduced ...
Tópico(s): Fluid Dynamics and Turbulent Flows
2016 - Springer Science+Business Media | Experiments in Fluids
Carlos Arce León, Roberto Merino-Martínez, Daniele Ragni, Francesco Avallone, Fulvio Scarano, Stefan Pröbsting, Mirjam Snellen, Dick G. Simons, Jesper Madsen,
Tópico(s): Wind and Air Flow Studies
2017 - Elsevier BV | Journal of Sound and Vibration
V. Fanotto, Mario Uccello, Irene Pecora, Lorenza Rimassa, Francesco Leone, Gerardo Rosati, Daniele Santini, Riccardo Giampieri, Samantha Di Donato, Gianluca Tomasello, Nicola Silvestris, Filippo Pietrantonio, Francesca Battaglin, Antonio Avallone, Mario Scartozzi, E.S. Lutrino, Davide Melisi, Lorenzo Antonuzzo, Antonio Pellegrino, Laura Ferrari, Roberto Bordonaro, Caterina Vivaldi, Lorenzo Gerratana, Silvia Bozzarelli, Roberto Filippi, Domenico Bilancia, Marco Russano, Giuseppe Aprile,
Second-line therapy has consistently demonstrated survival benefit if compared with best supportive care; however, there is limited evidence whether further lines of treatment may improve the prognosis of advanced gastric cancer (AGC) patients.Starting from a real-world cohort of 868 AGC patients, we retrospectively analyzed baseline parameters, tumor characteristics, and treatment data of those treated with at least three lines. Categorical features were described through cross-tables and chi-square ...
Tópico(s): Gastrointestinal Tumor Research and Treatment
2017 - AlphaMed Press | The Oncologist
Carlos Arce León, Roberto Merino-Martínez, Stefan Pröbsting, Daniele Ragni, Francesco Avallone,
The trailing edge of a NACA 0018 airfoil is modified through the attachment of serrations with different degrees of permeability. Acoustic beamforming is used to inspect the turbulent boundary layer-trailing edge noise emissions from the unmodified and serrated trailing edges. Different freestream velocities and angles of attack are investigated. The serration permeability is prescribed by having slits cut into the solid surface of the serrations in two different configurations. The results indicate ...
Tópico(s): Fluid Dynamics and Turbulent Flows
2017 - Springer Science+Business Media | Acoustics Australia
Gabriella Carrozza, Vittorio Manetti, Antonio Marotta, Roberto Canonico, Stefano Avallone,
Cloud Computing has been receiving great attention in the last few years due to the benefits it provides in terms of flexibility, scalability, virtualization and service provision. Nevertheless, many companies remain reluctant to such a cutting-edge technology due to the serious security issues affecting virtualized environments, especially in critical application scenarios where high safety and dependability levels are required. This work is aimed at discussing and presenting the main security ...
Tópico(s): IoT and Edge/Fog Computing
2013 - Springer Science+Business Media | Lecture notes in computer science
Antonio Barbato, Roberto Iacone, Giovanni Tarantino, Ornella Russo, Paolo Sorrentino, S. Avallone, Ferruccio Galletti, Eduardo Farinaro, Elisabetta Della Valle, Pasquale Strazzullo,
Tópico(s): Diet and metabolism studies
2009 - Springer Science+Business Media | Internal and Emergency Medicine
Erika Martinelli, Teresa Troiani, Claudia Cardone, Davide Ciardiello, N. Zanaletti, C. Borrelli, M. Terminiello, Antonio Avallone, Alfredo Falcone, Evaristo Maiello, Roberto Bordonaro, Daniele Santini, Carlo Garufi, Filippo Pietrantonio, Carmine Pinto, Giuseppe Santabarbara, Nicola Normanno, Fortunato Ciardiello,
Abstract Background The immune system plays a pivotal role in modulating response to monoclonal antibodies therapy in cancer. Novel immune-checkpoint inhibitors have demonstrated potent efficacy alone and in combinations with cytotoxic agents in several cancers. In this regard, avelumab in combination with cetuximab might be a relevant re-challenge strategy in RAS wild type (WT) metastatic colorectal cancer (mCRC) patients treated in first line with chemotherapy (CT) in combination with anti-epidermal ...
Tópico(s): Gastric Cancer Management and Outcomes
2019 - Elsevier BV | Annals of Oncology
Roberto Russo, Carmen De, Bice Avallone, Salvatore Magliocca, Maria Nieddu, Gianpiero Boatto, Roberta Troiano, Rosario Cuomo, Carla Cirillo, Carmen Avagliano, Claudia Cristiano, Giovanna La Rana, Giovanni Sarnelli, Antonio Calignano, Maria Grazia Rimoli,
Ketorolac is a powerful non-steroidal anti-inflammatory drug (NSAID), with a great analgesic activity, present on the Italian market since 1991. Despite the excellent therapeutic activity, the chronic use of ketorolac has long been limited owing to the high incidence of gastrointestinal and kidney side events. In our previous study, we demonstrated that ketorolac-galactose conjugate (ketogal), synthesized and tested in a single-dose study, was able to reduce ulcerogenicity, while preserving the high ...
Tópico(s): Peptidase Inhibition and Analysis
2017 - Frontiers Media | Frontiers in Pharmacology
Crescenzo D’Alterio, Antonio Avallone, Fabiana Tatangelo, Paolo Delrio, Biagio Pecori, Laura Cella, Alessia Pelella, Francesco Paolo D’Armiento, Chiara Carlomagno, Francesco Bianco, Lucrezia Silvestro, Roberto Pacelli, Maria Napolitano, Rosario Vincenzo Iaffaioli, Stefania Scala,
Despite the optimization of the local treatment of advanced rectal cancer (LARC), combination of preoperative chemoradiotherapy (CRT) and surgery, approximately one third of patients will develop distant metastases. Since the chemokine receptor CXCR4 has been implicated in metastasis development and prognosis in colorectal cancer, the role of the entire axis CXCR4-CXCL12-CXCR7 was evaluated to identify high relapse risk rectal cancer patients. Tumor specimens of 68 LARC patients undergoing surgery ...
Tópico(s): Colorectal and Anal Carcinomas
2013 - Wiley | International Journal of Cancer
Gerardo Rosati, Stefano Cordio, Giuseppe Aprile, Alfredo Butera, Antonio Avallone, Giuseppe Di Lucca, F. De Pauli, Héctor Soto Parrà, Giorgio Reggiardo, Roberto Bordonaro,
Tópico(s): Hepatocellular Carcinoma Treatment and Prognosis
2011 - Springer Science+Business Media | Investigational New Drugs
Roberto Vailati Facchini, Walter Bertazzolo, D. Zuliani, Ugo Bonfanti, Marco Caldín, Giancarlo Avallone, P. Roccabianca,
Abstract: Gammopathies associated with plasma cell neoplasms in a 15‐year‐old female spayed domestic shorthaired cat and a 9‐year‐old female spayed Rottweiler dog were evaluated by serum protein electrophoresis. In the cat, the plasma cell neoplasm was found in the liver and spleen, and an evaluable sample of bone marrow was not obtained. Some of the plasma cells had the morphologic appearance of flame cells. The paraprotein was confirmed as IgG based on agar gel immunodiffusion precipitation and ...
Tópico(s): Blood groups and transfusion
2010 - Wiley | Veterinary Clinical Pathology
Giorgia Tura, Barbara Brunetti, Elena Brigandì, Riccardo Rinnovati, Giuseppe Sarli, Giancarlo Avallone, Luisa Vera Muscatello, Roberto M. La Ragione, Andy E. Durham, Barbara Bacci,
Sarcoids are among the most common tumors diagnosed in equids; their association with bovine papillomaviruses (BPV) infection has been widely reported, but the mechanism of carcinogenesis has not been fully elucidated. To verify whether BPV infection causes dysregulation of the pRb-Cyclin D1-p16CDKN2A-p53 pathway as reported for human papillomavirus (HPV), the study employed immunohistochemistry to test 55 equine sarcoid biopsies for the expression of pRb, Cyclin D1, and p53 cell cycle regulatory ...
Tópico(s): Cancer Diagnosis and Treatment
2022 - Multidisciplinary Digital Publishing Institute | Veterinary Sciences
Roberto Merino-Martínez, Alejandro Rubio Carpio, Lourenço Tércio Lima Pereira, Steve van Herk, Francesco Avallone, Daniele Ragni, Marios Kotsonis,
The newly refurbished vertical tunnel (V-tunnel) at Delft University of Technology has been redesigned as a state-of-the-art facility for research in aeroacoustics (A-tunnel), as well as fundamental studies in laminar-turbulent transition and flow control. This manuscript focuses on the design and refurbishment aspects of the facility, including a description of the main modifications in the supporting structures and the drive system of the fan, with details of the flow conditioning and anechoic performance. ...
Tópico(s): Fluid Dynamics and Turbulent Flows
2020 - Elsevier BV | Applied Acoustics
Luigi Buonaguro, Andrea Mayer-Mokler, Roberto S. Accolla, Yuk Ting, Regina Heidenreich, Antonio Avallone, Ester Simeone, Alfred Koenigsrainer, Markus Loeffler, Cécile Gouttefangeas, Christian Flohr, Joerg Ludwig, Hans‐Georg Rammensee, Mercedes Iñarrairaegui, Sven Francque, Tanguy Chaumette, Toni Weinschenk, Carsten Reinhardt, Senta Ulrike Gnad-Vogt, Harpreet Singh,
TPS3135 Background: HCC is the third leading cause of death from cancer globally with an extremely variable 5-year survival rate. The HepaVac-101 phase I/II, first-in-man, therapeutic cancer vaccine single-arm clinical trial is performed as part of the HepaVac project, funded by the European Commission's 7th Framework Program under the Grant Agreement Nr. 602893 (www.hepavac.eu). The HepaVac-101 trial identification numbers are NCT03203005 (Clinical trials.gov) and 2015-003389-10 (EudraCT). and Methods: ...
Tópico(s): vaccines and immunoinformatics approaches
2018 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
Giovanna Trinchese, Fabiano Cimmino, Gina Cavaliere, Angela Catapano, Chiara Fogliano, Adriano Lama, Claudio Pirozzi, Claudia Cristiano, Roberto Russo, Lidia Petrella, Rosaria Meli, Giuseppina Mattace Raso, Marianna Crispino, Bice Avallone, Maria Pina Mollica,
The role of the liver in autism spectrum disorders (ASD), developmental disabilities characterized by impairments in social interactions and repetitive behavioral patterns, has been poorly investigated. In ASD, it has been shown a dysregulation of gut-brain crosstalk, a communication system able to influence metabolic homeostasis, as well as brain development, mood and cognitive functions. The liver, with its key role in inflammatory and metabolic states, represents the crucial metabolic organ in ...
Tópico(s): Child Nutrition and Feeding Issues
2022 - Multidisciplinary Digital Publishing Institute | Antioxidants