Roberto Malagò, Mirko D’Onofrio, Giulia Zamboni, Niccolò Faccioli, Massimo Falconi, Letizia Boninsegna, Roberto Pozzi Mucelli,
Diagnosis of malignancy and prognostic assessment continue to be problems in the management of nonfunctioning pancreatic endocrine tumors. Histologic examination is the reference standard. The aim of our study was to compare B-mode and contrast-enhanced sonographic findings regarding nonfunctioning pancreatic endocrine tumors. Signs of malignancy, such as Ki67 index and presence of hepatic metastasis, were considered.We retrospectively reviewed the cases of 38 consecutively registered patients with ...
Tópico(s): Neuroblastoma Research and Treatments
2009 - American Roentgen Ray Society | American Journal of Roentgenology
Rossella Graziani, A. Brandalise, M Bellotti, Riccardo Manfredi, Alberto Contro, Massimo Falconi, Letizia Boninsegna, Roberto Pozzi Mucelli,
Tópico(s): Neuroblastoma Research and Treatments
2010 - Springer Science+Business Media | La radiologia medica
Patrizia Bottoni, Bruno Giardina, Alberto Vitali, Alma Boninsegna, Roberto Scatena,
Drug induced cell differentiation represents a promising experimental model for proteomic analysis of cancer cells. In fact, by modulating and monitoring neoplastic cell differentiation it could be possible to identify cytodifferentiation related protein expression changes that can be subsequently utilized in vivo as potential cancer biomarkers. One main advantage of this approach is the significant reduction of biological variability normally observed in clinical biomarker research, with important ...
Tópico(s): Cancer, Lipids, and Metabolism
2009 - Elsevier BV | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
Stefano Partelli, Letizia Boninsegna, Roberto Salvia, Claudio Bassi, Paolo Pederzoli, Massimo Falconi,
The appropriate surgical approach of a pancreatic multifocal disease that skips the body of the gland remains unknown. We sought to analyze a parenchyma-sparing surgical technique consisting of a middle-preserving pancreatectomy (MPP) evaluating feasibility, safety, and oncological and functional outcomes.Between 1999 and 2007, 5 patients affected by pancreatic benign or slow malignant multicentric body-sparing disease underwent MPP.There were 3 men and 2 women with a median age of 35 years (range ...
Tópico(s): Pancreatitis Pathology and Treatment
2009 - Elsevier BV | The American Journal of Surgery
Riccardo Manfredi, Anna Ventriglia, William Mantovani, Sara Mehrabi, Enrico Boninsegna, Giuseppe Zamboni, Roberto Salvia, Roberto Pozzi Mucelli,
Tópico(s): Pediatric Hepatobiliary Diseases and Treatments
2014 - Springer Science+Business Media | European Radiology
Giovanni Foti, Letizia Boninsegna, Massimo Falconi, Roberto Pozzi Mucelli,
Tópico(s): Neuroblastoma Research and Treatments
2013 - Springer Science+Business Media | La radiologia medica
Salvatore Paiella, Giovanni Marchegiani, Marco Miotto, Anna Malpaga, Harmony Impellizzeri, G. Montagnini, Tommaso Pollini, Chiara Nessi, Giovanni Butturini, Paola Capelli, Ilaria Posenato, Aldo Scarpa, Mirko D’Onofrio, Riccardo De Robertis, Sara Cingarlini, Letizia Boninsegna, Claudio Bassi, Roberto Salvia, Luca Landoni,
Cystic pancreatic neuroendocrine tumors (CPanNETs) represent an uncommon variant of pancreatic neuroendocrine tumors (PanNETs). Due to their rarity, there is a lack of knowledge with regard to clinical features and postoperative outcome.The prospectively maintained surgical database of a high-volume institution was queried, and 46 resected CPanNETs were detected from 1988 to 2015. Clinical, demographic, and pathological features and survival outcomes of CPanNETs were described and matched with a population ...
Tópico(s): Lung Cancer Research Studies
2017 - Karger Publishers | Neuroendocrinology
Marco Boninsegna, Gino Marioni, Roberto Stramare, R Bottin, Jacopo Tesei, Cosimo de Filippis, Alberto Staffieri,
Tópico(s): Pneumothorax, Barotrauma, Emphysema
2005 - Decker Medicine | The Journal of Otolaryngology
Giovanni Carturan, R. Campostrini, Lorenzo Tognana, S. Boninsegna, Roberto Dal Toso, Renzo Dal Monte,
Tópico(s): 3D Printing in Biomedical Research
2006 - Springer Science+Business Media | Journal of Sol-Gel Science and Technology
Anna Ventriglia, Riccardo Manfredi, Sara Mehrabi, Enrico Boninsegna, Riccardo Negrelli, Beatrice Pedrinolla, Roberto Pozzi Mucelli,
Tópico(s): Pancreatitis Pathology and Treatment
2014 - Springer Nature | Abdominal Radiology
Riccardo Negrelli, Riccardo Manfredi, Beatrice Pedrinolla, Enrico Boninsegna, Anna Ventriglia, Sara Mehrabi, Luca Frulloni, Roberto Pozzi Mucelli,
Tópico(s): Gastrointestinal disorders and treatments
2014 - Springer Science+Business Media | European Radiology
Giovanni Marchegiani, Valentina Todaro, Enrico Boninsegna, Riccardo Negrelli, Binit Sureka, Deborah Bonamini, Roberto Salvia, Riccardo Manfredi, Roberto Pozzi Mucelli, Claudio Bassi,
Tópico(s): MRI in cancer diagnosis
2018 - Springer Science+Business Media | European Radiology
G. Carturan, Roberto Dal Toso, S. Boninsegna, Renzo Dal Monte,
The conjugation of inorganic materials with biological systems has attracted research interest, as a consequence of the availability of the sol–gel process, operating under experimental conditions compatible with biomolecules and whole cells. In Section 2, the merits and limitations of alkoxide-based sol–gel silica as an immobilization material are presented and discussed with particular attention to the confinement of living cells and cell clusters. Biosil technology is based on the encapsulation ...
Tópico(s): Bone Tissue Engineering Materials
2004 - Royal Society of Chemistry | Journal of Materials Chemistry
Enrico Boninsegna, Riccardo Manfredi, Riccardo Negrelli, Giacomo Avesani, Sara Mehrabi, Roberto Pozzi Mucelli,
Abstract Purpose To define imaging criteria of benign and malignant nature in patients with main pancreatic duct (MPD) stenosis. Materials-methods S-MRCPs of 35 patients with pancreatitis and 14 with adenocarcinoma were evaluated. Results Adenocarcinoma caused higher prevalence of complete stenosis (14/14–100% vs 17/35–49%), dilated side-branches (14/14–100% vs 18/35–51%) and lower prevalence of duct-penetrating sign (0/14–0% vs 31/35–89%). The number of stenoses was higher in benign conditions (mean 1.4 Vs ...
Tópico(s): Pediatric Hepatobiliary Diseases and Treatments
2016 - Elsevier BV | Clinical Imaging
Gino Marioni, E Castegnaro, Claudia Staffieri, Roberto Rinaldi, Luciano Giacomelli, Marco Boninsegna, Andy Bertolin, Alberto Staffieri,
Tópico(s): Infectious Diseases and Tuberculosis
2006 - Springer Science+Business Media | Aging Clinical and Experimental Research
Riccardo Negrelli, Enrico Boninsegna, Giacomo Avesani, Giulia Zamboni, Lorenzo Brozzi, Luca Frulloni, Riccardo Manfredi, Roberto Pozzi Mucelli,
This study aimed to evaluate magnetic resonance imaging findings of autoimmune pancreatitis (AIP) and to find radiological patterns that could differentiate type 1 and type 2 AIP.Eighty-four patients with diagnosis of AIP were enrolled. Image analysis included pancreatic signal intensity abnormalities, enhancement pattern, extrapancreatic involvement, and main pancreatic duct alterations.Pancreatic parenchyma resulted in hypointensity on T1-weighted images in 65 (98.5%) of 66 cases in type 1 and in ...
Tópico(s): Pancreatitis Pathology and Treatment
2018 - Lippincott Williams & Wilkins | Pancreas
Enrico Boninsegna, Riccardo Manfredi, Anna Ventriglia, Riccardo Negrelli, Beatrice Pedrinolla, Sara Mehrabi, Armando Gabbrielli, Roberto Pozzi Mucelli,
Tópico(s): Gallbladder and Bile Duct Disorders
2015 - Springer Science+Business Media | European Radiology
Enrico Boninsegna, Giulia Zamboni, Davide Facchinelli, Charikleia Triantopoulou, Nicholas Gourtsoyiannis, Maria Chiara Ambrosetti, Dino Veneri, Achille Ambrosetti, Roberto Pozzi Mucelli,
To describe CT characteristics of primary pancreatic lymphoma (PPL), a rare disease with features in common with adenocarcinoma.Fourteen patients were enrolled. CT: unenhanced scan, contrast-enhanced pancreatic and venous phases. Image analysis: tumour location; peri-pancreatic vessel encasement; necrosis; enlarged lymph nodes; fat stranding; enlarged bile duct and pancreatic duct; neoplasm longest dimension, volume and density.Histopathological diagnoses: follicular non-Hodgkin lymphoma (5/14), diffuse ...
Tópico(s): Gastrointestinal Tumor Research and Treatment
2018 - Springer Nature | Insights into Imaging
Enrico Boninsegna, Riccardo Negrelli, Giulia Zamboni, Giorgia Tedesco, Riccardo Manfredi, Roberto Pozzi Mucelli,
Tópico(s): Pancreatic and Hepatic Oncology Research
2017 - Elsevier BV | European Journal of Radiology
Luca Landoni, Giovanni Marchegiani, Tommaso Pollini, Sara Cingarlini, Mirko D’Onofrio, Paola Capelli, Riccardo De Robertis, Maria Vittoria Davì, Antonio Amodio, Harmony Impellizzeri, Anna Malpaga, Marco Miotto, Letizia Boninsegna, Lorenzo Crepaz, Chiara Nessi, Caterina C. Zingaretti, Salvatore Paiella, Alessandro Esposito, Luca Casetti, Giuseppe Malleo, Massimiliano Tuveri, Giovanni Butturini, Roberto Salvia, Aldo Scarpa, Massimo Falconi, Claudio Bassi,
Objective: The objective of the present analysis is 2-fold: first, to define the evolution of time trends on the surgical approach to pancreatic neuroendocrine neoplasms (Pan-NENs); second, to perform a complete analysis of the predictors of oncologic outcome. Background: Reflecting their rarity and heterogeneity, Pan-NENs represent a clinical dilemma. In particular, there is a scarcity of data regarding their long-term follow-up after surgical resection. Methods: From the Institutional Pan-NEN database, ...
Tópico(s): Neuroblastoma Research and Treatments
2017 - Lippincott Williams & Wilkins | Annals of Surgery
Davide Facchinelli, Sokol Sina, Enrico Boninsegna, Alex Borin, Maria Chiara Tisi, Francesco Piazza, Greta Scapinello, Elena Maiolo, Stefan Hohaus, Alberto Zamò, Michele Merli, Piero Maria Stefani, Federica Mellone, Marco Basso, Roberto Sartori, Chiara Rusconi, Alice Parisi, Erminia Manfrin, Mauro Krampera, Marco Ruggeri, Carlo Visco, Cristina Tecchio,
Primary pancreatic lymphoma (PPL) is a rare disease representing 0.1% of malignant lymphomas, which lacks well-defined diagnostic and therapeutic protocols.To describe PPL clinical, diagnostic and histological characteristics, together with therapy and outcome, in a relatively large series of patients.The study includes 39 PPL patients, aged ≥15 years, observed from January 2005 to December 2018, in 8 Italian Institutions.The main symptoms were abdominal pain (58%) and jaundice (47%). Lactate dehydrogenase ...
Tópico(s): Gastrointestinal Tumor Research and Treatment
2020 - Wiley | European Journal Of Haematology
Giuseppe Zamboni, Marco Chincarini, Maria Chiara Ambrosetti, Francesco Lombardo, Riccardo Negrelli, Enrico Boninsegna, Roberto Pozzi Mucelli,
Tópico(s): Medical Imaging Techniques and Applications
2017 - Springer Science+Business Media | Electronic Commerce Research
Francesco Bussu, C. Graziani, Roberto Gallus, Antonio Cittadini, Jacopo Galli, Eugenio De Corso, Giovanni Di Cintio, Maddalena Corbi, Giovanni Almadori, Alma Boninsegna, Gaetano Paludetti, Alessandro Sgambato,
Altered immune responses have been reported in head and neck cancer, and some of these responses have been associated with poor clinicaloutcomes. A multiple-array technology platform was used to simultaneously evaluate the levels of 25 cytokines. Pre-treatment serum levelswere evaluated in 31 HNSCC patients and 6 healthy controls. The levels of 8 cytokines, specifically IL-1ra, IL-2, IL-5, IL-6, IL-8, IL-17, IFN-γand IP-10, were significantly higher in patients than in controls. Among cancer patients ...
Tópico(s): NF-κB Signaling Pathways
2018 - Pacini Editore Medicina | Acta Otorhinolaryngologica Italica
Giacomo Avesani, Riccardo Negrelli, Enrico Boninsegna, Luca Frulloni, Roberto Manfredi, Raffaella Pozzi Mucelli,
Tópico(s): Pancreatitis Pathology and Treatment
2016 - Springer Nature | Insights into Imaging
Giacomo Avesani, Riccardo Negrelli, Enrico Boninsegna, Luca Frulloni, Roberto Manfredi, Roberto Pozzi Mucelli,
Tópico(s): Pancreatitis Pathology and Treatment
2016 - Springer Nature | Insights into Imaging
Davide Rizzo, C. Graziani, Roberto Gallus, Gian Franco Zannoni, Donatella Lucchetti, Claudio Parrilla, Alma Boninsegna, Jacopo Galli, Gaetano Paludetti, Francesco Bussu, Alessandro Sgambato,
Marker di staminalità nei carcinomi squamocellulari del cavo orale e orofaringe in relazione al sito di origine e a infezione da HPV: implicazioni cliniche.In questo studio è stata esaminata l’espressione di potenziali marcatori di staminalità nei carcinomi della testa e collo (HNSCC) per valutarne il loro possibile ruolo clinico. Sono stati arruolati 69 carcinomi squamocellulari del cavo orale (OSCC) e dell’orofaringe (OPSCC) primitivi e non precedentemente sottoposti a trattamento, raccogliendo i ...
Tópico(s): Cancer-related molecular mechanisms research
2020 - Pacini Editore Medicina | Acta Otorhinolaryngologica Italica
R. Nosadini, Angelo Avogaro, Alessandro Doria, Paola Fioretto, Roberto Trevisan, Anna Morocutti,
... J 204: 399– 403, 1982. 68 Federspil G, Boninsegna A, Picchi G, Zanon G, and De Palo ...
Tópico(s): Metabolism and Genetic Disorders
1989 - Wiley | Diabetes/Metabolism Reviews
Henrik Friis, Nyagosya Range, Claus Kristensen, Pernille Kæstel, John Changalucha, Wabyahe L. M. Malenganisho, Henrik Krarup, Pascal Magnussen, Anders Andersen, G. Bosch, Adronie Verbrugghe, Myriam Hesta, Jens J. Holst, Antonius van der Poel, Geert O. Janssens, W.H. Hendriks, Marı́a Monagas, Nasiruddin Khan, Cristina Andrés‐Lacueva, Mireia Urpí-Sardà, Mónica Vázquez-Agell, Rosa M. Lamuela‐Raventós, Ramón Estruch, Paola Palozza, Diana Bellovino, Roberto De Simone, Alma Boninsegna, Francesco Cellini, Giovanni Monastra, S. Gaetani, Yoshio Tanaka, Kazuki Mochizuki, Nanae Fukaya, Mayuko Shimada, Toshinao Goda, Krystal J. Merrells, Heather Blewett, Jennifer A. Jamieson, Chris Taylor, Minyoung Suh, Robert Clarke, M Shipley, Jane Armitage, R. T. Collins, W. E. Harris,
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2009 - Cambridge University Press | British Journal Of Nutrition
Maria Ausiliatrice Puglisi, N. Saulnier, Alessandro Sgambato, F. Rafanelli, Marta Barba, A.C. Piscaglia, Alma Boninsegna, Ezio Giorda, Rita Carsetti, Felice Giuliante, Sergio Alfieri, Roberto Persiani, Antonio Cittadini, Antonio Gasbarrini,
Tópico(s): Liver physiology and pathology
2009 - Elsevier BV | Digestive and Liver Disease
Roberto Pozzi Mucelli, Riccardo Negrelli, Enrico Boninsegna, Sara Mehrabi, Riccardo Manfredi,
La pancreatitis autoinmune (PAI) es una forma distinta de pancreatitis crónica, que se caracteriza por un mecanismo patogénico autoinmune. Su frecuencia es levemente mayor en los pacientes de sexo masculino (60%) y la edad promedio de presentación oscila entre los 40 y 60 años, aunque el rango etario es mucho más amplio (de 14 a 80 años). Desde el punto de vista histológico, la PAI se presenta con un infiltrado inflamatorio denso, de extensión variable, que puede ser focal o comprometer difusamente ...
Tópico(s): Gastrointestinal disorders and treatments
2016 - Georg Thieme Verlag | Revista Argentina de Radiología / Argentinian Journal of Radiology