José Luis Martı́nez Vidal, Patricia Plaza‐Bolaños, Roberto Romero‐González, Antonia Garrido Frenich,
Pesticides are widely applied and they can produce a variety of transformation products (TPs), through different pathways and mechanisms. Nowadays there is a growing interest related to the determination of pesticide TPs in several matrices (environmental, food and biological samples), due to these compounds can be more toxic and persistent than parent compounds, and some of them can be used as markers of exposure to different pesticides. Although solid-phase extraction (SPE) is mainly used for the ...
Tópico(s): Pharmacological Effects and Assays
2009 - Elsevier BV | Journal of Chromatography A
María Luz Gómez-Pérez, Patricia Plaza‐Bolaños, Roberto Romero‐González, José Luis Martı́nez Vidal, Antonia Garrido Frenich,
A method based on gas chromatography-atmospheric pressure chemical ionization-mass spectrometry (GC-APCI-MS) has been developed for the analysis of pesticides in meat by using quadrupole-time of flight mass spectrometry (QTOF-MS). Ionization and MS conditions were studied for 71 compounds, although only 51 showed acceptable performance. The protonated form of the analytes was mainly found ([M + H]+), although some compounds generated the molecular ion (M+•). A fast and generic extraction procedure was ...
Tópico(s): Pharmacological Effects and Assays
2014 - American Chemical Society | Journal of the American Society for Mass Spectrometry
Noelia M. Valera-Tarifa, Patricia Plaza‐Bolaños, Roberto Romero‐González, José Luis Martínez‐Vidal, Antonia Garrido‐Frenich,
A new analytical method has been developed for the simultaneous determination of 4 nitrofuran metabolites in seafood by ultra-high performance liquid chromatography coupled to triple quadrupole tandem mass spectrometry (UHPLC–QqQ-MS/MS). The extraction procedure was based on a simultaneous acidic hydrolysis and derivatization using 2-nitrobenzaldehyde (2-NBA), followed by a solid-phase extraction (SPE). Recovery was studied by spiking blank samples at two concentration levels (1 and 10 μg/kg) and recoveries ...
Tópico(s): Mass Spectrometry Techniques and Applications
2013 - Elsevier BV | Journal of Food Composition and Analysis
María Luz Gómez-Pérez, Patricia Plaza‐Bolaños, Roberto Romero‐González, José Luis Martínez‐Vidal, Antonia Garrido‐Frenich,
A database has been created for the simultaneous analysis of more than 350 pesticides and veterinary drugs (including antibiotics) using ultra-high performance liquid chromatography coupled to high resolution Orbitrap mass spectrometry (UHPLC–Orbitrap-MS). This is a comprehensive exact mass database built using the Exactive-Orbitrap analyzer. The developed database includes exact masses of the target ions and retention time data, and allows the automatic search of the included compounds. Generic chromatographic ...
Tópico(s): Animal Ecology and Behavior Studies
2012 - Elsevier BV | Journal of Chromatography A
M.M. Aguilera-Luiz, Patricia Plaza‐Bolaños, Roberto Romero‐González, José Luis Martı́nez Vidal, Antonia Garrido Frenich,
Tópico(s): Insect and Pesticide Research
2011 - Springer Science+Business Media | Analytical and Bioanalytical Chemistry
Juan Antonio Padilla‐Sánchez, Patricia Plaza‐Bolaños, Roberto Romero‐González, Nieves Barco-Bonilla, José Luis Martínez‐Vidal, Antonia Garrido‐Frenich,
An analytical methodology has been developed for the simultaneous extraction of 13 phenolic compounds, including chlorophenols (CPs), nitrophenols (NTPs), cresols and alkylphenols (APs) in different types of wastewater (WW) effluents. A solid-phase extraction (SPE) method has been optimized prior to the determination by gas chromatography coupled to triple quadrupole tandem mass spectrometry (GC-QqQ-MS/MS). Due to the complexity of the matrix, a comparison study of matrix-matched-calibration (MMC) and ...
Tópico(s): Mass Spectrometry Techniques and Applications
2011 - Elsevier BV | Talanta
Juan Antonio Padilla‐Sánchez, Patricia Plaza‐Bolaños, Roberto Romero‐González, Antonia Garrido‐Frenich, José Luis Martı́nez Vidal,
Due to the different physico-chemical properties of phenols, the development of a methodology for the simultaneous extraction and determination of phenolic compounds belonging to several families, such as chlorophenols (CPs), alkylphenols (APs), nitrophenols (NTPs) and cresols is difficult. This study shows the development and validation of a method for the analysis of 13 phenolic compounds (including CPs, APs, NTPs and cresols) in agricultural soils. For this purpose, a quick, easy, cheap, effective, ...
Tópico(s): Toxic Organic Pollutants Impact
2010 - Elsevier BV | Journal of Chromatography A
Patricia Plaza‐Bolaños, Roberto Romero‐González, Antonia Garrido Frenich, José Luis Martı́nez Vidal,
An alternative method has been developed to determine more than 50 pesticides in alcoholic beverages using hollow fibre liquid phase microextraction (HF-LPME) followed by ultra-high pressure liquid chromatography coupled to tandem mass spectrometry (UHPLC–MS/MS), without any further clean-up step. Pesticides were extracted from the sample to the organic solvent immobilized in the fibre and they were desorbed in methanol prior to chromatographic analysis. Experimental parameters related to microextraction ...
Tópico(s): Analytical Chemistry and Chromatography
2008 - Elsevier BV | Journal of Chromatography A
Noelia López-Gutiérrez, Roberto Romero‐González, Patricia Plaza‐Bolaños, José Luis Martı́nez Vidal, Antonia Garrido Frenich,
A method has been developed and validated for the simultaneous detection and quantification of phytochemicals in nutraceutical products obtained from green tea. For that purpose, ultra-high performance liquid chromatography coupled to single-stage Orbitrap high resolution mass spectrometry (UHPLC–Orbitrap-MS) has been used. A database containing 37 compounds has been used for the detection and identification of the target compounds. The developed methodology was based on solid–liquid extraction, ...
Tópico(s): Phytoestrogen effects and research
2014 - Elsevier BV | Food Chemistry
M.M. Aguilera-Luiz, Roberto Romero‐González, Patricia Plaza‐Bolaños, José Luis Martı́nez Vidal, Antonia Garrido Frenich,
A simple and rapid method is described for the determination of veterinary drug (VD) residues in honey samples using turbulent flow chromatography coupled to ultrahigh-performance liquid chromatography–Orbitrap mass spectrometry (TFC-UHPLC-Orbitrap-MS). Honey samples were diluted with an aqueous solution of Na2EDTA (0.1 M). Then, they were injected into the chromatographic system including a TFC column. Afterward, the analytes were transferred to an UHPLC analytical column, where they were determined ...
Tópico(s): Bee Products Chemical Analysis
2013 - American Chemical Society | Journal of Agricultural and Food Chemistry
M.M. Aguilera-Luiz, Roberto Romero‐González, Patricia Plaza‐Bolaños, José Luis Martı́nez Vidal, Antonia Garrido Frenich,
Tópico(s): Antibiotics Pharmacokinetics and Efficacy
2013 - Springer Science+Business Media | Analytical and Bioanalytical Chemistry
Nieves Barco-Bonilla, Roberto Romero‐González, Patricia Plaza‐Bolaños, José Luis Martı́nez Vidal, Antonia Garrido Frenich,
The occurrence of priority organic pollutants in wastewater (WW) effluents was evaluated in a semi-arid area, characterized by a high agricultural and tourism activity, as Almeria province (Southeastern Spain). Twelve wastewater treatment plants (WWTPs) were sampled in three campaigns during 2011, obtaining a total of 33 WW samples, monitoring 226 compounds, including pesticides, polycyclic aromatic hydrocarbons (PAHs), phenolic compounds and volatile organic compounds (VOCs). Certain banned organochlorine ...
Tópico(s): Environmental Toxicology and Ecotoxicology
2013 - Elsevier BV | The Science of The Total Environment
Noelia López-Gutiérrez, Roberto Romero‐González, Patricia Plaza‐Bolaños, José Luis Martínez‐Vidal, Antonia Garrido‐Frenich,
Tópico(s): Environmental Toxicology and Ecotoxicology
2012 - Springer Science+Business Media | Food Analytical Methods
Nieves Barco-Bonilla, Patricia Plaza‐Bolaños, Noelia Ma Valera Tarifa, Roberto Romero‐González, José Luis Martı́nez Vidal, Antonia Garrido Frenich,
The analysis of brominated flame retardants, such as polybrominated diphenyl ethers (PBDEs), has received increased interest because of their toxicity and ubiquity. According to European Union Directive 2008/105/EC, the development of highly sensitive and selective methods capable of determining PBDEs at low concentration levels (<0.5 ng/L) is necessary. In this work, an SPE method was developed for the analysis of the six PBDEs (BDE-28, BDE-47, BDE-99, BDE-100, BDE-153, BDE-154) specified by the aforementioned ...
Tópico(s): Effects and risks of endocrine disrupting chemicals
2013 - Wiley | Journal of Separation Science
María Luz Gómez-Pérez, Roberto Romero‐González, Patricia Plaza‐Bolaños, Emmanuelle Génin, José Luis Martı́nez Vidal, Antonia Garrido Frenich,
A multiresidue and multiclass method for the simultaneous determination of more than 350 compounds including pesticides, biopesticides and veterinary drugs in different meat matrices (beef, pork and chicken) by ultra-high performance liquid chromatography coupled to Orbitrap MS has been developed. In the present study, the determination of fragments was accomplished as an essential tool for a reliable identification of compounds using high resolution MS. To obtain these fragments, different strategies ...
Tópico(s): Pharmacological Effects and Assays
2014 - Wiley | Journal of Mass Spectrometry
Tópico(s): Comparative Literary Analysis and Criticism
2020 - University of Santiago de Compostela | Boletín Galego de Literatura
Tópico(s): Historical and Modern Theater Studies
1998 - Editorial Galaxia | Anuario de estudios literarios galegos
Patricia Plaza‐Bolaños, Juan Antonio Padilla‐Sánchez, Antonia Garrido‐Frenich, Roberto Romero‐González, José Luis Martínez‐Vidal,
A comprehensive survey of the occurrence and fate of pesticides and organic contaminants in soils from an intensive agricultural area devoted to horticultural production in plastic-based greenhouses has been performed to determine if the operation under integrated pest management practices has contributed to reduce the levels of these compounds. Almería province (south-eastern Spain) was selected for the case study. 38 agricultural soil samples (each sample corresponds to an independent private greenhouse) ...
Tópico(s): Pharmaceutical and Antibiotic Environmental Impacts
2012 - Royal Society of Chemistry | Journal of Environmental Monitoring
Antonia Garrido‐Frenich, Roberto Romero‐González, José Luis Martínez‐Vidal, Patricia Plaza‐Bolaños, Luis Cuadros‐Rodríguez, M.A. Herrera-Abdo,
The assessment of the recovery factor with the analyte concentration in meat samples has been studied for the determination of organochlorine and organophosphorus pesticides in meat by gas chromatography-triple quadrupole mass spectrometry (GC–MS/MS). For that purpose, recent IUPAC recommendations, which distinguishes between two terms, recovery factor and apparent recovery, have been followed. Besides, the systematic error due to the matrix effect has been evaluated by a new term recently proposed, ...
Tópico(s): Pharmacological Effects and Assays
2006 - Elsevier BV | Journal of Chromatography A
Nieves Barco-Bonilla, Patricia Plaza‐Bolaños, José Luis Fernández-Moreno, Roberto Romero‐González, Antonia Garrido Frenich, José Luis Martı́nez Vidal,
Tópico(s): Water Quality Monitoring and Analysis
2011 - Springer Science+Business Media | Analytical and Bioanalytical Chemistry
Juan Antonio Padilla‐Sánchez, Roberto Romero‐González, Patricia Plaza‐Bolaños, Antonia Garrido Frenich, José Luis Martı́nez Vidal,
Abstract A three‐year study of the levels of pesticide residues and organic contaminants in agricultural soils has been carried out in an important intensive agricultural area in Spain. Although traditional farming practices are being replaced by integrated pest management programs (IPMs), extensive phytosanitary application and inadequate farm practices (e.g. burning of vegetable and plastic material) have been carried out during decades, and occurrence of residues and persistent pollutants was expected. ...
Tópico(s): Toxic Organic Pollutants Impact
2014 - Wiley | CLEAN - Soil Air Water
Nieves Barco-Bonilla, Roberto Romero‐González, Patricia Plaza‐Bolaños, Antonia Garrido Frenich, José Luis Martı́nez Vidal,
Tópico(s): Pharmaceutical and Antibiotic Environmental Impacts
2010 - Elsevier BV | Journal of Chromatography A
José Luis Martı́nez Vidal, Juan Antonio Padilla‐Sánchez, Patricia Plaza‐Bolaños, Antonia Garrido Frenich, Roberto Romero‐González,
Abstract Due to the wide range of pesticides that can be used in agriculture, the development of fast multiresidue methods that simultaneously determine polar and non-polar pesticides is greatly demanded. This study shows the development and validation of a multiresidue method for the analysis of 98 non-polar pesticides and 28 polar pesticides in soil. A simultaneous extraction step by pressurized liquid extraction was utilized. The optimum results were obtained using ethyl acetatemethanol (3:1, ...
Tópico(s): Antibiotics Pharmacokinetics and Efficacy
2010 - Oxford University Press | Journal of AOAC International
Nieves Barco-Bonilla, Roberto Romero‐González, Patricia Plaza‐Bolaños, José Luis Martı́nez Vidal, Antonio Arjona Castro, Isabel Martín, Juan José Sendra Salas, Antonia Garrido Frenich,
A comprehensive survey of the occurrence of organic compounds in 30 wastewater (WW) effluent samples from 21 urban wastewater treatment plants (WWTPs) from both secondary and tertiary treatments was carried out in the Mediterranean and Atlantic basins of the Andalusia region (south of Spain). For each sample, a total of 226 compounds including pesticides and some transformation products, polycyclic aromatic hydrocarbons (PAHs), phenolic compounds and volatile organic compounds (VOCs) were monitored with ...
Tópico(s): Water Treatment and Disinfection
2013 - Royal Society of Chemistry | Environmental Science Processes & Impacts
Nieves Barco-Bonilla, Roberto Romero‐González, Patricia Plaza‐Bolaños, José Luis Fernández-Moreno, Antonia Garrido Frenich, José Luis Martı́nez Vidal,
The objective of this study was the optimization and comparison of two extraction methods for the determination of polycyclic aromatic hydrocarbons (PAHs) in wastewater (WW). A distribution study of the target compounds between the aqueous phase and the suspended particulate matter (SPM) has been performed in order to establish whether the analysis of both phases is necessary. In this sense, the feasibility of stir bar sorptive extraction (SBSE) and solid-phase extraction (SPE) for the determination ...
Tópico(s): Analytical Chemistry and Chromatography
2011 - Elsevier BV | Analytica Chimica Acta
Roberto Romero‐González, M.M. Aguilera-Luiz, Patricia Plaza‐Bolaños, Antonia Garrido Frenich, José Luis Martı́nez Vidal,
Veterinary drugs (VDs) can remain in milk as a consequence of their use in livestock. In order to control the levels of VD residues in milk, screening methodologies can be applied for a rapid discrimination among negative and non-negative samples. In a second stage, non-negative samples are classified as negative or positive samples by using a confirmation method. Pre-target screening methods in low resolution MS (LRMS) are normally applied, but the number of analytes is limited, whereas the information ...
Tópico(s): Pharmaceutical and Antibiotic Environmental Impacts
2011 - Elsevier BV | Journal of Chromatography A
... Adolfo Torrado Ballester, Álvaro Cunqueiro, Gonzalo Torrente, and Roberto Vidal Bolaño.
Tópico(s): Medieval Iberian Studies
2011 - Purdue University Press | CLCWeb Comparative Literature and Culture
Nieves Barco-Bonilla, Roberto Romero‐González, Patricia Plaza‐Bolaños, Antonia Garrido Frenich, José Luis Martı́nez Vidal, Juan José Sendra Salas, Isabel López Martín,
Abstract A distribution study of 204 organic contaminants, including polar and nonpolar pesticides, polycyclic aromatic hydrocarbons (PAHs), and phenolic compounds, between the two phases composing municipal wastewater (WW) from a small community (aqueous phase and suspended particulate matter (SPM)) has been performed to establish whether the compounds can be more prone to be in the aqueous or in the solid phase, depending on their hydrophobicity. Therefore, a general procedure is proposed to evaluate ...
Tópico(s): Microplastics and Plastic Pollution
2013 - Taylor & Francis | Desalination and Water Treatment
Roberto Romero‐González, Patricia Plaza‐Bolaños, Rocío I Limón-Garduza, José Luis Martínez‐Vidal, Antonia Garrido Frenich,
Abstract A method for the determination of 14 biopesticides and piperonyl butoxide (PBO), often applied in organic farming, in vegetables and fruits has been developed. Extraction was performed using the Quick, Easy, Cheap, Effective, Rugged, and Safe method, and the determination was carried out by ultra-performance LC/MS/MS in 9 min. Several different food commodities were evaluated as representative matrixes, namely, cucumber, tomato, pepper (high water content), and strawberry and orange (high ...
Tópico(s): Insect Pest Control Strategies
2014 - Oxford University Press | Journal of AOAC International
Roberto Romero González, José Luis Fernández Moreno, Patricia Plaza‐Bolaños, Antonia Garrido Frenich, José Luis Martı́nez Vidal,
En los alimentos se pueden encontrar un gran número de sustancias tóxicas, tales como plaguicidas, antibióticos y toxinas, presentando distintos orígenes (naturales o sintéticos) y niveles de toxicidad para la salud humana. Este tipo de compuestos se encuentran generalmente a muy bajas concentraciones en matrices muy complejas, por lo que es necesario la utilización de metodologías lo más fiables posibles. En este sentido, el empleo de las técnicas cromatográficas (de gases y de líquidos) acopladas ...
Tópico(s): Effects and risks of endocrine disrupting chemicals
2007 - Ministry of Health of Spain | Revista Española de Salud Pública