Bruce K. Patterson, José Guevara-Coto, Ram Yogendra, Edgar B. Francisco, Emily Long, Amruta Pise, Hallison Rodrigues, Purvi Parikh, Javier Mora, Rodrígo Mora,
Expression of CCR5 and its cognate ligands have been implicated in COVID-19 pathogenesis, consequently therapeutics directed against CCR5 are being investigated. Here, we explored the role of CCR5 and its ligands across the immunologic spectrum of COVID-19. We used a bioinformatics approach to predict and model the immunologic phases of COVID so that effective treatment strategies can be devised and monitored. We investigated 224 individuals including healthy controls and patients spanning the COVID- ...
Tópico(s): vaccines and immunoinformatics approaches
2021 - Frontiers Media | Frontiers in Immunology
Javier Mora, Rodrígo Mora, Bruno Lomonte, José Marı́a Gutiérrez,
Background Envenomations by the snake Bothrops asper represent a serious medical problem in Central America and parts of South America. These envenomations concur with drastic local tissue pathology, including a prominent edema. Since lymph flow plays a role in the maintenance of tissue fluid balance, the effect of B. asper venom on collecting lymphatic vessels was studied. Methodology/Principal Findings B. asper venom was applied to mouse mesentery, and the effects were studied using an intravital ...
Tópico(s): Marine Invertebrate Physiology and Ecology
2008 - Public Library of Science | PLoS neglected tropical diseases
Produção Nacional
Revisado por pares
José Diego Botezelli, Rodrigo F Mora, Rodrigo Augusto Dalia, Leandro Pereira de Moura, Lucieli Teresa Cambri, Ana Carolina Ghezzi, Fabrício Azevedo Voltarelli, Maria AR Mello,
This study aimed to analyze the effects of exercise at the aerobic/anaerobic transition on the markers of non-alcoholic fatty liver disease (NAFLD), insulin sensitivity and the blood chemistry of rats kept on a fructose-rich diet. We separated 48 Wistar rats into two groups according to diet: a control group (balanced diet AIN-93 G) and a fructose-rich diet group (60% fructose). The animals were tested for maximal lactate-steady state (MLSS) in order to identify the aerobic/anaerobic metabolic transition ...
Tópico(s): Diet and metabolism studies
2010 - BioMed Central | Lipids in Health and Disease
Rinaldo Puga-Gómez, Yariset Ricardo-Delgado, Chaumey Rojas-Iriarte, Leyanis Céspedes-Henriquez, Misleidys Piedra-Bello, Dania Vega-Mendoza, Noelvia Pestana Pérez, Beatriz Paredes-Moreno, Meiby Rodríguez-González, Carmen Valenzuela‐Silva, Belinda Sánchez-Ramírez, Laura Rodríguez-Noda, Rocmira Pérez-Nicado, Raúl González-Mugica, Tays Hernández-García, Talía Fundora-Barrios, Martha Dubet Echevarría, Juliet Enríquez-Puertas, Yenicet Infante-Hernández, Ariel Palenzuela-Díaz, Evelyn Gato-Orozco, Yanet Chappi-Estévez, Julio Cesar Francisco-Pérez, Miladi Suarez-Martinez, Ismavy C. Castillo-Quintana, Sonsire Fernández-Castillo, Yanet Climent-Ruíz, Darielys Santana-Mederos, Yanelda García-Vega, María Eugenia Toledo-Romaní, Delaram Doroud, Alireza Biglari, Yury Valdés-Balbín, Dagmar García-Rivera, Vicente Vérez-Bencomo, María Elena Mesa-Herrera, Yarmila García-Cristiá, Leonor Verdecia-Sánchez, Rafael del Valle Rodríguez, Yudalvies Oquendo-de la Cruz, Daysi Álvarez-Montalvo, Randy Grillo-Fortún, Liset López-González, Omaida Fonte Galindo, Yeseni Reyes-González, Ana Beatriz González-Álvarez, Linet Gorrita-Mora, Rodrigo Valera-Fernández, Ivis Ontivero-Pino, Marisel Martínez-Pérez, Esperanza Caballero-González, Aniurka Garcés-Hechavarría, Dayle Martínez-Bedoya, Maite Medina-Nápoles, Yeney Regla Domínguez-Pentón, Yadira Cazañas-Quintana, Thais Fundora Barrios, Diana Rosa Hernández Fernández, Gretchen Bergado, Ivette Orosa-Vázquez, Franciscary Pi-Estopiñán, Marianniz Díaz-Hernández, Otto Cruz-Sui, Enrique Noa-Romero, Arilia García-López, Sandra Rivadereira Muro, Gerardo Baró-Román,
To evaluate a heterologous vaccination scheme in children 3-18 years old (y/o) combining two SARS-CoV-2r- receptor binding domain (RBD)protein vaccines.A phase I/II open-label, adaptive, and multicenter trial evaluated the safety and immunogenicity of two doses of FINLAY-FR-2 (subsequently called SOBERANA 02) and the third heterologous dose of FINLAY-FR-1A (subsequently called SOBERANA Plus) in 350 children 3-18 y/o in Havana Cuba. Primary outcomes were safety (phase I) and safety/immunogenicity (phase ...
Tópico(s): Vaccine Coverage and Hesitancy
2022 - Elsevier BV | International Journal of Infectious Diseases
Produção Nacional
Revisado por pares
Masha T. van der Sande, Jennifer S. Powers, Thomas W. Kuyper, Natalia Norden, Beatriz Salgado‐Negret, Jarcilene Silva de Almeida‐Cortez, Frans Bongers, Diego Delgado, Daisy H. Dent, Géraldine Derroire, Mário M. Espírito‐Santo, Juan Manuel Dupuy, Geraldo Wilson Fernandes, Bryan Finegan, Mayra E. Gavito, José Luis Hernández‐Stefanoni, Catarina C. Jakovac, Isabel L. Jones, Maria das Dores Magalhães Veloso, Jorge A. Meave, Francisco Mora, Rodrigo Muñoz, Nathalia Pérez-Cárdenas, Daniel Piotto, Esteban Álvarez‐Dávila, Yasmani Cáceres‐Siani, Coralie Dalban-Pilon, Aurélie Dourdain, Dan V. Du, Daniel García Villalobos, Yule Roberta Ferreira Nunes, Arturo Sánchez‐Azofeifa, Lourens Poorter,
The recovery of soil conditions is crucial for successful ecosystem restoration and, hence, for achieving the goals of the UN Decade on Ecosystem Restoration. Here, we assess how soils resist forest conversion and agricultural land use, and how soils recover during subsequent tropical forest succession on abandoned agricultural fields. Our overarching question is how soil resistance and recovery depend on local conditions such as climate, soil type and land-use history. For 300 plots in 21 sites ...
Tópico(s): Conservation, Biodiversity, and Resource Management
2022 - Royal Society | Philosophical Transactions of the Royal Society B Biological Sciences
Luis A. Herrera, Alfredo Hidalgo‐Miranda, Nancy Reynoso‐Noverón, Abelardo Meneses‐García, Alfredo Mendoza-Vargas, Juan Pablo Reyes‐Grajeda, Felipe Vadillo‐Ortega, Alberto Cedro‐Tanda, Fernando Peñaloza, Emmanuel Frías-Jiménez, Cristian Arriaga-Canon, Rosaura Ruiz, Ofelia Angulo, Imelda López-Villaseñor, Carlos Amador‐Bedolla, Diana Vilar‐Compte, Patricia Cornejo, Mireya Cisneros-Villanueva, Eduardo Hurtado-Córdova, Mariana Cendejas-Orozco, José S. Hernández-Morales, Bernardo Moreno, Irwin A. Hernández-Cruz, César A. Herrera, Francisco José Ferraro García, Miguel Á. González-Woge, Paulina Munguía-Garza, Fernando Luna-Maldonado, Antonia Sánchez-Vizcarra, Vincent G. Osnaya, Nelly Medina-Molotla, Yair Alfaro‐Mora, Rodrigo E. Cáceres-Gutiérrez, Laura Tolentino-García, Patricia Rosas-Escobar, Sergio A. Román-González, Marco A. Escobar-Arrazola, Julio C. Canseco-Méndez, Diana R. Ortiz-Soriano, Julieta Domínguez-Ortiz, Ana D. González-Barrera, Diana I. Aparicio‐Bautista, Armando Cruz‐Rangel, Ana Paula Alarcón-Zendejas, Laura Contreras‐Espinosa, Rodrigo González‐Barrios, Lissania Guerra-Calderas, Marco Antonio Meraz-Rodríguez, Michel Montalvo-Casimiro, Rogelio Montiel-Manríquez, Karla Torres-Arciga, Daniela Venegas, Vasti Thamara Juárez-González, Xiadani Guajardo-Barreto, Verónica Monroy-Martínez, Daniel Guillén, Jacquelina Fernández, Juliana Herrera, Renato León‐Rodríguez, Israel Canela-Pérez, Blanca H. Ruíz-Ordaz, Rafael Ricardo Valdez‐Vázquez, Jennifer Bertin-Montoya, María Dolores Niembro-Ortega, Liudmila Villegas-Acosta, Daniela López-Castillo, Andrea Soriano‐Ríos, Michael Gastelum-Ramos, Tonatiuh Zamora-Barandas, Jorge Morales-Baez, María García-Rodríguez, Mariano García-Martínez, Erik Nieto-Patlán, Maricarmen Quirasco, Irma López-Martı́nez, José Ernesto Ramírez–González, Hiram Olivera-Díaz, Noé Escobar-Escamilla,
The aim of this study was to investigate the feasibility of saliva sampling as a non-invasive and safer tool to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and to compare its reproducibility and sensitivity with nasopharyngeal swab samples (NPS). The use of sample pools was also investigated.A total of 2107 paired samples were collected from asymptomatic healthcare and office workers in Mexico City. Sixty of these samples were also analyzed in two other independent laboratories ...
Tópico(s): Dental Research and COVID-19
2021 - Elsevier BV | International Journal of Infectious Diseases
Produção Nacional
Revisado por pares
Carlos Maldonado, Freddy Mora, Rodrigo Iván Contreras‐Soto, Sunny Ahmar, Jen‐Tsung Chen, Antônio Teixeira do Amaral Júnior, Carlos Alberto Scapim,
Genomic selection models were investigated to predict several complex traits in breeding populations of Zea mays L. and Eucalyptus globulus Labill. For this, the following methods of Machine Learning (ML) were implemented: (i) Deep Learning (DL) and (ii) Bayesian Regularized Neural Network (BRNN) both in combination with different hyperparameters. These ML methods were also compared with Genomic Best Linear Unbiased Prediction (GBLUP) and different Bayesian regression models [Bayes A, Bayes B, Bayes Cπ, ...
Tópico(s): Genetics and Plant Breeding
2020 - Frontiers Media | Frontiers in Plant Science
Antonio Cobo, Elena Villalba‐Mora, Rodrigo Pérez‐Rodríguez, Xavier Ferré, Walter Escalante Puente de la Vega, Cristian Moral, Leocadio Rodríguez‐Mañas,
The present paper describes a system for older people to self-administer the 30-s chair stand test (CST) at home without supervision. The system comprises a low-cost sensor to count sit-to-stand (SiSt) transitions, and an Android application to guide older people through the procedure. Two observational studies were conducted to test (i) the sensor in a supervised environment (n = 7; m = 83.29 years old, sd = 4.19; 5 female), and (ii) the complete system in an unsupervised one (n = 7; age 64-74 years old; 3 female). ...
Tópico(s): Context-Aware Activity Recognition Systems
2020 - Multidisciplinary Digital Publishing Institute | Sensors
Marco A. Andonegui-Elguera, Yair Alfaro‐Mora, Rodrigo E. Cáceres-Gutiérrez, Claudia Haydeé Saraí Caro-Sánchez, Luis A. Herrera, José Díaz‐Chávez,
Vasculogenic mimicry (VM) is the formation of vascular channels lacking endothelial cells. These channels are lined by tumor cells with cancer stem cell features, positive for periodic acid-Schiff, and negative for CD31 staining. The term VM was introduced by Maniotis in 1999, who reported this phenomenon in highly aggressive uveal melanomas; since then, VM has been associated with poor prognosis, tumor aggressiveness, metastasis, and drug resistance in several tumors, including breast cancer. It ...
Tópico(s): Breast Cancer Treatment Studies
2020 - Frontiers Media | Frontiers in Oncology
Produção Nacional
Revisado por pares
Maga Gei, Danaë M. A. Rozendaal, Lourens Poorter, Frans Bongers, Janet I. Sprent, Mira Garner, T. Mitchell Aide, José Luís Andrade, Patricia Balvanera, Justin M. Becknell, Pedro H. S. Brancalion, George A. L. Cabral, Ricardo G. César, Robin L. Chazdon, Rebecca J. Cole, Gabriel Dalla Colletta, Ben de Jong, Julie S. Denslow, Daisy H. Dent, Saara J. DeWalt, Juan Manuel Dupuy, Sandra M. Durán, Mário M. Espírito‐Santo, Geraldo Wilson Fernandes, Yule Roberta Ferreira Nunes, Bryan Finegan, Vanessa Granda Moser, Jefferson S. Hall, José Luis Hernández‐Stefanoni, André Braga Junqueira, Deborah Kennard, Edwin Lebrija‐Trejos, Susan G. Letcher, Madelon Lohbeck, E. Marín-Spiotta, Miguel Martínez‐Ramos, Jorge A. Meave, Duncan N. L. Menge, Francisco Mora, Rodrigo Muñoz, Robert Muscarella, Susana Ochoa‐Gaona, Edith Orihuela-Belmonte, Rebecca Ostertag, Marielos Peña‐Claros, Eduardo A. Pérez‐García, Daniel Piotto, Peter B. Reich, Casandra Reyes‐García, Jorge Rodríguez‐Velázquez, Eunice Romero, Lucía Sanaphre‐Villanueva, Arturo Sánchez‐Azofeifa, Naomi B. Schwartz, Jarcilene Silva de Almeida‐Cortez, Jarcilene Silva de Almeida‐Cortez, Whendee L. Silver, Vanessa de Souza Moreno, Benjamin W. Sullivan, Nathan G. Swenson, María Uriarte, Michiel van Breugel, Hans van der Wal, Maria das Dores Magalhães Veloso, Hans F. M. Vester, Ima Célia Guimarães Vieira, Jess K. Zimmerman, Jennifer S. Powers,
The nutrient demands of regrowing tropical forests are partly satisfied by nitrogen-fixing legume trees, but our understanding of the abundance of those species is biased towards wet tropical regions. Here we show how the abundance of Leguminosae is affected by both recovery from disturbance and large-scale rainfall gradients through a synthesis of forest inventory plots from a network of 42 Neotropical forest chronosequences. During the first three decades of natural forest regeneration, legume ...
Tópico(s): Plant Water Relations and Carbon Dynamics
2018 - Nature Portfolio | Nature Ecology & Evolution
Produção Nacional
Revisado por pares
Saverio Caini, Wladimir J. Alonso, Ángel Balmaseda, Alfredo Bruno, Patricia Bustos, Leticia Castillo, Celina de Lozano, Doménica de Mora, Rodrigo Fasce, Walquíria Aparecida Ferreira de Almeida, Gabriela Kusznierz, Jenny Lara, María Luisa Matute, Brechla Moreno, Cláudio Maierovitch Pessanha Henriques, Juan Manuel Rudi, Clotilde El‐Guerche Séblain, François Schellevis, John Paget,
Introduction The increased availability of influenza surveillance data in recent years justifies an actual and more complete overview of influenza epidemiology in Latin America. We compared the influenza surveillance systems and assessed the epidemiology of influenza A and B, including the spatio-temporal patterns of influenza epidemics, in ten countries and sub-national regions in Latin America. Methods We aggregated the data by year and country and characteristics of eighty-two years were analysed. ...
Tópico(s): COVID-19 epidemiological studies
2017 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
J. Antonio Baeza, Lunden Simpson, Louis J. Ambrosio, Nathalia Mora, Rodrigo Guéron, Michael J. Childress,
We used the Caribbean spiny lobster Panulirus argus, one of the largest brooding invertebrates in the Western Atlantic, to test for the presence/absence of active parental care and to explore reproductive performance in large brooding marine organisms. Given [i] the compact and large embryo masses produced by P. argus, [ii] the expected disproportional increase in brooding costs with increasing embryo mass size, and [iii] the theoretical allometry of egg production with increasing body size, we predicted ...
Tópico(s): Parasite Biology and Host Interactions
2016 - BioMed Central | BMC Zoology
Produção Nacional
Revisado por pares
Adriane Esquivel‐Muelbert, Timothy R. Baker, Kyle G. Dexter, Simon L. Lewis, Hans ter Steege, Gabriela López‐González, Abel Monteagudo Mendoza, Roel Brienen, Ted R. Feldpausch, Nigel C. A. Pitman, Alfonso Alonso, Geertje van der Heijden, Marielos Peña‐Claros, Manuel Ahuite, Miguel Alexiaides, Esteban Álvarez‐Dávila, Alejandro Araujo Murakami, Luzmila Arroyo, Milton Aulestia, Henrik Balslev, Jorcely Barroso, René Boot, Ángela Cano, Víctor Chama Moscoso, James A. Comiskey, Fernando Cornejo Valverde, Francisco Dallmeier, Douglas C. Daly, Nállarett Dávila, Joost F. Duivenvoorden, Álvaro Javier Duque Montoya, Terry L. Erwin, Anthony Di Fiore, Todd S. Fredericksen, A C., Roosevelt García‐Villacorta, Therany Gonzales, Juan Ernesto Guevara, Eurídice N. Honorio Coronado, Isau Huamantupa‐Chuquimaco, E. Jiménez, Timothy J. Killeen, Yadvinder Malhi, Casimiro Mendoza, Hugo F. Mogollón, Peter M. Jørgensen, Juan Carlos Montero, Bonifacio Mostacedo, William Nauray, David Neill, Percy Núñez Vargas, Sonia Palacios‐Ramos, Walter Palacios Cuenca, Nadir Pallqui Camacho, Julie Peacock, Juan Fernando Phillips, Georgia Pickavance, Carlos Alberto Quesada, Hirma Ramírez‐Angulo, Zorayda Restrepo, Carlos Reynel, Marcos Ríos Paredes, María Cristina Peñuela-Mora, Rodrigo Sierra, Marcos Silveira, Pablo R. Stevenson, Juliana Stropp, John Terborgh, Milton Tirado, Marisol Toledo, Armando Torres‐Lezama, María Natalia Umaña, Ligia E. Urrego, Rodolfo Vásquez Martínez, Luis Valenzuela Gamarra, César I. A. Vela, Emilio Vilanova, Vincent Antoine Vos, Patricio von Hildebrand, Corine Vriesendorp, Ophelia Wang, Kenneth R. Young, Charles E. Zartman, Oliver L. Phillips,
Within the tropics, the species richness of tree communities is strongly and positively associated with precipitation. Previous research has suggested that this macroecological pattern is driven by the negative effect of water‐stress on the physiological processes of most tree species. This implies that the range limits of taxa are defined by their ability to occur under dry conditions, and thus in terms of species distributions predicts a nested pattern of taxa distribution from wet to dry areas. ...
Tópico(s): Species Distribution and Climate Change
2016 - Wiley | Ecography
Produção Nacional
Revisado por pares
Robin L. Chazdon, Eben N. Broadbent, Danaë M. A. Rozendaal, Frans Bongers, Angélica M. Almeyda Zambrano, T. Mitchell Aide, Patricia Balvanera, Justin M. Becknell, Vanessa Boukili, Pedro H. S. Brancalion, Dylan Craven, Jarcilene Silva de Almeida‐Cortez, George A. L. Cabral, Ben de Jong, Julie S. Denslow, Daisy H. Dent, Saara J. DeWalt, Juan Manuel Dupuy, Sandra M. Durán, Mário M. Espírito‐Santo, María Fandiño, Ricardo G. César, Jefferson S. Hall, José Luis Hernández‐Stefanoni, Catarina C. Jakovac, André Braga Junqueira, Deborah Kennard, Susan G. Letcher, Madelon Lohbeck, Miguel Martínez‐Ramos, Paulo Eduardo dos Santos Massoca, Jorge A. Meave, Rita C. G. Mesquita, Francisco Mora, Rodrigo Muñoz, Robert Muscarella, Yule Roberta Ferreira Nunes, Susana Ochoa‐Gaona, Edith Orihuela-Belmonte, Marielos Peña‐Claros, Eduardo A. Pérez‐García, Daniel Piotto, Jennifer S. Powers, Jorge Rodríguez‐Velázquez, Eunice Romero, Jorge Ruíz, Juan Saldarriaga, Arturo Sánchez‐Azofeifa, Naomi B. Schwartz, Marc K. Steininger, Nathan G. Swenson, María Uriarte, Michiel van Breugel, Hans van der Wal, Maria das Dores Magalhães Veloso, Hans F. M. Vester, Ima Célia Guimarães Vieira, Tony Vizcarra Bentos, G. Bruce Williamson, Lourens Poorter,
Regrowth of tropical secondary forests following complete or nearly complete removal of forest vegetation actively stores carbon in aboveground biomass, partially counterbalancing carbon emissions from deforestation, forest degradation, burning of fossil fuels, and other anthropogenic sources. We estimate the age and spatial extent of lowland second-growth forests in the Latin American tropics and model their potential aboveground carbon accumulation over four decades. Our model shows that, in 2008, ...
Tópico(s): Conservation, Biodiversity, and Resource Management
2016 - American Association for the Advancement of Science | Science Advances
Produção Nacional
Revisado por pares
Lourens Poorter, Frans Bongers, T. Mitchell Aide, Angélica M. Almeyda Zambrano, Patricia Balvanera, Justin M. Becknell, Vanessa Boukili, Pedro H. S. Brancalion, Eben N. Broadbent, Robin L. Chazdon, Dylan Craven, Jarcilene Silva de Almeida‐Cortez, George A. L. Cabral, Ben de Jong, Julie S. Denslow, Daisy H. Dent, Saara J. DeWalt, Juan Manuel Dupuy, Sandra M. Durán, Mário M. Espírito‐Santo, María Fandiño, Ricardo G. César, Jefferson S. Hall, José Luis Hernández‐Stefanoni, Catarina C. Jakovac, André Braga Junqueira, Deborah Kennard, Susan G. Letcher, Juan‐Carlos Licona, Madelon Lohbeck, E. Marín-Spiotta, Miguel Martínez‐Ramos, Paulo Eduardo dos Santos Massoca, Jorge A. Meave, Rita C. G. Mesquita, Francisco Mora, Rodrigo Muñoz, Robert Muscarella, Yule Roberta Ferreira Nunes, Susana Ochoa‐Gaona, Alexandre A. Oliveira, Edith Orihuela-Belmonte, Marielos Peña‐Claros, Eduardo A. Pérez‐García, Daniel Piotto, Jennifer S. Powers, Jorge Rodríguez‐Velázquez, Eunice Romero, Jorge Ruíz, Juan Saldarriaga, Arturo Sánchez‐Azofeifa, Naomi B. Schwartz, Marc K. Steininger, Nathan G. Swenson, Marisol Toledo, María Uriarte, Michiel van Breugel, Hans van der Wal, Maria das Dores Magalhães Veloso, Hans F. M. Vester, Alberto Vicentini, Ima Célia Guimarães Vieira, Tony Vizcarra Bentos, G. Bruce Williamson, Danaë M. A. Rozendaal,
An analysis of above-ground biomass recovery during secondary succession in forest sites and plots, covering the major environmental gradients in the Neotropics. More than half the world's tropical forests are the product of secondary growth, following anthropogenic disturbance. It is therefore important to know how quickly these secondary forests recover sufficiently to provide ecosystem services equivalent to those of old-growth forest. These authors focus on carbon sequestration in Neotropical ...
Tópico(s): Forest Management and Policy
2016 - Nature Portfolio | Nature
Produção Nacional
Revisado por pares
Lourens Poorter, Masha T. van der Sande, Jill Thompson, E.J.M.M. Arets, Alejandro Alarcón, Javier Álvarez-Sánchez, Nataly Ascarrunz, Patricia Balvanera, Guadalupe Barajas-Guzmán, Alice Boit, Frans Bongers, Fabrício Alvim Carvalho, Fernando Casanoves, Guadalupe Cornejo‐Tenorio, Flávia R. C. Costa, Carolina V. Castilho, Joost F. Duivenvoorden, Loïc Dutrieux, Brian J. Enquist, Fernando Fernández-Méndez, Bryan Finegan, Lorraine H. L. Gormley, John R. Healey, Marcel R. Hoosbeek, Guillermo Ibarra‐Manríquez, André Braga Junqueira, Carolina Levis, Juan Carlos Licona, Leila Sheila Silva Lisbôa, William E. Magnusson, Miguel Martínez‐Ramos, Angelina Martínez‐Yrízar, Lucieta Guerreiro Martorano, Lindsay C. Maskell, Lucas Mazzei, Jorge A. Meave, Francisco Mora, Rodrigo Muñoz, Christopher J. Nytch, Marcelo Petratti Pansonato, Terence W. Parr, Horacio Paz, Eduardo A. Pérez‐García, Lyliana Y. Rentería, Jorge Rodríguez‐Velázquez, Danaë M. A. Rozendaal, Ademir Roberto Ruschel, Boris Sakschewski, Beatriz Salgado‐Negret, Juliana Schietti, Margareth Simões, Fergus Sinclair, Priscila Figueira de Souza, Fernanda Coelho de Souza, Juliana Stropp, Hans ter Steege, Nathan G. Swenson, Kirsten Thonicke, Marisol Toledo, María Uriarte, P. van der Hout, Patricia W. Walker, Nelson Rodríguez, Marielos Peña‐Claros,
Abstract Aim Tropical forests store 25% of global carbon and harbour 96% of the world's tree species, but it is not clear whether this high biodiversity matters for carbon storage. Few studies have teased apart the relative importance of forest attributes and environmental drivers for ecosystem functioning, and no such study exists for the tropics. Location Neotropics. Methods We relate aboveground biomass ( AGB ) to forest attributes (diversity and structure) and environmental drivers (annual rainfall ...
Tópico(s): Plant Water Relations and Carbon Dynamics
2015 - Wiley | Global Ecology and Biogeography
Mauricio Campos‐Mora, Rodrigo A. Morales, Francisco Pérez, Tania Gajardo, Javier Campos, Diego Catalán, Juan Carlos Aguillón, Karina Pino‐Lagos,
During allograft rejection, several immune cell types, including dendritic cells, CD4 + and CD8 + T cells among others, recirculate between the graft and the nearest draining lymph node, resulting in immunity against the ‘foreign’ tissue. Regulatory CD4 + T cells are critical for controlling the magnitude of the immune response and may act to promote or maintain tolerance. They are characterized by the expression of CD25 and Foxp3, and more recently, Neuropilin‐1 (Nrp1). The role of these suppressor cells ...
Tópico(s): Immune Cell Function and Interaction
2014 - Wiley | Immunology and Cell Biology
Mauricio Campos‐Mora, Rodrigo A. Morales, Tania Gajardo, Diego Catalán, Karina Pino‐Lagos,
In the immune system, Neuropilin-1 (Nrp1) is a molecule that plays an important role in establishing the immunological synapse between dendritic cells (DCs) and T cells. Recently, Nrp1 has been identified as a marker that seems to distinguish natural T regulatory (nTreg) cells, generated in the thymus, from inducible T regulatory (iTreg) cells raised in the periphery. Given the crucial role of both nTreg and iTreg cells in the generation and maintenance of immune tolerance, the ability to phenotypically ...
Tópico(s): Neurogenesis and neuroplasticity mechanisms
2013 - Frontiers Media | Frontiers in Immunology
Produção Nacional
Revisado por pares
Mauricio Venegas, Mónica V Alvarado-Mora, Rodrigo A. Villanueva, João Renato Rebello Pinho, Flair José Carrilho, Stephen Locarnini, Lilly Yuen, Javier Brahm,
Molecular epidemiological data concerning the hepatitis B virus (HBV) in Chile are not known completely. Since the HBV genotype F is the most prevalent in the country, the goal of this study was to obtain full HBV genome sequences from patients infected chronically in order to determine their subgenotypes and the occurrence of resistance-associated mutations. Twenty-one serum samples from antiviral drug-naive patients with chronic hepatitis B were subjected to full-length PCR amplification, and both ...
Tópico(s): Liver Disease Diagnosis and Treatment
2011 - Wiley | Journal of Medical Virology
Octavio Castillo, Ivar Vidal-Mora, Rodrigo Campos, A. Fonerón, Miguel Feria-Flores, Reinaldo Gómez, Francisco Sepúlveda,
La cirugía endoscópica transluminal a través de orificios naturales (NOTES™) es una tecnología emergente, que permite realizar procedimientos quirúrgicos sin el uso de incisiones abdominales. Sin embargo existen limitaciones respecto al equipamiento disponible para simular la cirugía tradicional. Nuestro objetivo es presentar nuestra experiencia con la técnica de nefrectomía transvaginal NOTES con el uso de instrumentos laparoscópicos estándar. Presentamos dos pacientes de sexo femenino de 23 y 26 ...
Tópico(s): Renal cell carcinoma treatment
2009 - Elsevier BV | Actas Urológicas Españolas
Puig Mora, Rodrigo J. Carbajo, Antonio Pineda‐Lucena, Manuel M. Sánchez del Pino, Enríque Pérez‐Payá,
The role of hydrophobic amino acids in the formation of hydrophobic cores as one of the major driving forces in protein folding has been extensively studied. However, the implication of neutral solvent-exposed amino acids is less clear and available information is scarce. We have used a combinatorial approach to study the structural relevance of three solvent-exposed residues (Tyr(327), Thr(329), and Gln(331)) located in thebeta-sheet of the tetramerization domain of the tumor suppressor p53 (p53TD). ...
Tópico(s): RNA modifications and cancer
2007 - Wiley | Proteins Structure Function and Bioinformatics
Arne Luz, M. Diana, Beatriz Orozco‐Mora, Rodrigo Restrepo‐Molina, Judith Trujillo‐Perez, Félix J. Tapia,
Erythema dyschromicum perstans (EDP) is a pigmentary disease of unknown etiology in which damage to basal cells is thought to be mediated by adhesion molecules. The aim of this study was to characterize the histopathology and immunopathology of EDP. Forty-three patients from Medellín, Colombia, with the diagnosis of EDP were evaluated. Skin biopsy specimens were obtained for histopathology and immunohistochemistry, using monoclonal antibodies directed against the following markers: CD4, CD8, CD56, ...
Tópico(s): Autoimmune Bullous Skin Diseases
2006 - Wiley | International Journal of Dermatology
Pablo Mora, Rodrigo Olea, Ricardo Troncoso, Jorge Zanelli,
A gauge invariant action principle, based on the idea of transgression forms, is proposed. The action extends the Chern-Simons form by the addition of a boundary term that makes the action gauge invariant (and not just quasi-invariant). Interpreting the spacetime manifold as cobordant to another one, the duplication of gauge fields in spacetime is avoided. The advantages of this approach are particularly noticeable for the gravitation theory described by a Chern-Simons lagrangian for the AdS group, ...
Tópico(s): Noncommutative and Quantum Gravity Theories
2006 - Springer Nature | Journal of High Energy Physics
Viviana E. Nicotra, María F. Mora, Rodrigo A. Iglesias, Ana M. Baruzzi,
The influence of pH on aggregate formation and changes in the structure of thionine monomers in solution has been determined. Spectroscopic data (UV–vis and 1H NMR) revealed that a free base form of the dye is formed at basic pH values, which displays highly hydrophobic behavior. The cationic monomeric form can be photoreduced in both organic and aqueous solution, while the free base form did not show any photoactivity in such media.
Tópico(s): Photodynamic Therapy Research Studies
2006 - Elsevier BV | Dyes and Pigments
Pablo A. Mora, Rodrigo Olea, Ricardo Troncoso, Jorge Zanelli,
A finite action principle for Chern-Simons AdS gravity is presented. The construction is carried out in detail first in five dimensions, where the bulk action is given by a particular combination of the Einstein-Hilbert action with negative cosmological constant and a Gauss-Bonnet term; and is then generalized for arbitrary odd dimensions. The boundary term needed to render the action finite is singled out demanding the action to attain an extremum for an appropriate set of boundary conditions. ...
Tópico(s): Noncommutative and Quantum Gravity Theories
2004 - Springer Nature | Journal of High Energy Physics
José Arturo Molina-Mora, Diana Chinchilla-Montero, Maribel Chavarría-Azofeifa, Alejandro Ulloa‐Morales, Rebeca Campos-Sánchez, Rodrígo Mora, Leming Shi, Fernando García,
Abstract Pseudomonas aeruginosa is an opportunistic pathogen that thrives in diverse environments and causes a variety of human infections. Pseudomonas aeruginosa AG1 (PaeAG1) is a high-risk sequence type 111 (ST-111) strain isolated from a Costa Rican hospital in 2010. PaeAG1 has both blaVIM-2 and blaIMP-18 genes encoding for metallo-β-lactamases, and it is resistant to β-lactams (including carbapenems), aminoglycosides, and fluoroquinolones. Ciprofloxacin (CIP) is an antibiotic commonly used to treat ...
Tópico(s): Tuberculosis Research and Epidemiology
2020 - Nature Portfolio | Scientific Reports
Pooria Norouzi, Sirine Maalej, Rodrigo Mora,
The development of digital twins leads to the pathway toward intelligent buildings. Today, the overwhelming rate of data in buildings carries a high amount of information that can provide an opportunity for a digital representation of the buildings and energy optimization strategies in the Heating, Ventilation, and Air Conditioning (HVAC) systems. To implement a successful energy management strategy in a building, a data-driven approach should accurately forecast the HVAC features, in particular ...
Tópico(s): Energy Load and Power Forecasting
2023 - Multidisciplinary Digital Publishing Institute | Buildings
Bruce K. Patterson, Edgar B. Francisco, Ram Yogendra, Emily Long, Amruta Pise, Hallison Rodrigues, Eric W. Hall, Mónica Herrera, Purvi Parikh, José Guevara-Coto, Timothy J. Triche, Paul T. Scott, Saboor Hekmati, Dennis T. Maglinte, Xaiolan Chang, Rodrígo Mora, Javier Mora,
The recent COVID-19 pandemic is a treatment challenge in the acute infection stage but the recognition of chronic COVID-19 symptoms termed post-acute sequelae SARS-CoV-2 infection (PASC) may affect up to 30% of all infected individuals. The underlying mechanism and source of this distinct immunologic condition three months or more after initial infection remains elusive. Here, we investigated the presence of SARS-CoV-2 S1 protein in 46 individuals. We analyzed T-cell, B-cell, and monocytic subsets ...
Tópico(s): COVID-19 Clinical Research Studies
2022 - Frontiers Media | Frontiers in Immunology
Ignacio Tiznado-Aitken, Rodrigo Mora, Gabriel Oyarzún, Jaime Vergara, Giovanni Vecchio,
Structural socio-economic and institutional limitations can affect the implementation of cycling infrastructure. More stringent cycling infrastructure standards aiming to solve deficiencies might exacerbate disparities, especially in poor districts with fragmentary governance . Using an audit and quantitative and spatial analysis of cycleways, this paper examines to what extent structural inequalities and governance issues affect the availability and quality of cycling infrastructure, considering ...
Tópico(s): Smart Parking Systems Research
2022 - Elsevier BV | Transportation Research Part D Transport and Environment
Carsten Geiß, Elvira Salas, José Guevara-Coto, Anne Régnier‐Vigouroux, Rodrígo Mora,
Macrophages are innate immune cells with a dynamic range of reversible activation states including the classical pro-inflammatory (M1) and alternative anti-inflammatory (M2) states. Deciphering how macrophages regulate their transition from one state to the other is key for a deeper understanding of inflammatory diseases and relevant therapies. Common regulatory motifs reported for macrophage transitions, such as positive or double-negative feedback loops, exhibit a switchlike behavior, suggesting ...
Tópico(s): Sphingolipid Metabolism and Signaling
2022 - Multidisciplinary Digital Publishing Institute | Cells