Produção Nacional
Revisado por pares
Xufen Zeng, Krista A Varady, Xiangdong Wang, Giovanni Targher, Christopher D. Byrne, Reema Tayyem, Giovanni Latella, Ina Bergheim, Rodrigo Valenzuela, Jacob George, Carolyn Newberry, Ju‐Sheng Zheng, Elena S. George, C Wendy Spearman, Meropi Kontogianni, Danijela Ristić-Medić, Wilza Arantes Ferreira Peres, Gamze Yurtdaş Depboylu, Wanshui Yang, Xu Chen, Fredrik Rosqvist, Christos S. Mantzoros, Luca Valenti, Hannele Yki‐Järvinen, Antonella Mosca, Silvia Sookoian, Anoop Misra, Yusuf Yılmaz, Won Kim, Yasser Fouad, Giada Sebastiani, Vincent Wai‐Sun Wong, Fredrik Åberg, Yu Jun Wong, Pian-hong Zhang, Francisco J. Bermúdez‐Silva, Yan Ni, Monica Lupșor‐Platon, Wah‐Kheong Chan, Nahúm Méndez‐Sánchez, Robert J. de Knegt, Shahinul Alam, Sombat Treeprasertsuk, Li Wang, Mulong Du, Tiejun Zhang, Ming‐Lung Yu, Huijie Zhang, Xingshun Qi, Xin Liu, Kanokwan Pinyopornpanish, Yu‐Chen Fan, Kaijun Niu, Josep C. Jiménez‐Chillarón, Ming‐Hua Zheng,
Metabolic dysfunction-associated fatty liver disease (MAFLD) or metabolic dysfunction-associated steatotic liver disease (MASLD), has become the leading cause of chronic liver disease worldwide. Optimal dietary intervention strategies for MAFLD are not standardized. This study aimed to achieve consensus on prevention of MAFLD through dietary modification. A multidisciplinary panel of 55 international experts, including specialists in hepatology, gastroenterology, dietetics, endocrinology and other ...
Tópico(s): Nutritional Studies and Diet
2024 - Elsevier BV | Metabolism
Cynthia Barrera, Rodrigo Valenzuela, Rodrigo Chamorro, Karla A. Bascuñán, Jorge Sandoval, N. Sabag, Francesca Valenzuela, María-Paz Valencia, Claudia Puigrredon, Alfonso Valenzuela,
Maternal diet during pregnancy is relevant for fatty acid supply during fetal life and lactation. Arachidonic (AA) and docosahexaenoic (DHA) acids are also relevant for the normal growth and development of brain and visual system. AA and DHA provided by the mother to the fetus and infant are directly associated with maternal dietary intake and body stores. Our aim was to evaluate the impact of maternal diet, specially referring to the quality of fatty acid intake, in a sample of Chilean women during ...
Tópico(s): Nutritional Studies and Diet
2018 - Multidisciplinary Digital Publishing Institute | Nutrients
Karla A. Bascuñán, Rodrigo Valenzuela, Rodrigo Chamorro, Alejandra Valencia, Cynthia Barrera, Claudia Puigrredon, Jorge Sandoval, Alfonso Valenzuela,
Chilean diets are characterized by a low supply of n-3 polyunsaturated fatty acids (n-3 PUFA), which are critical nutrients during pregnancy and lactation, because of their role in brain and visual development. DHA is the most relevant n-3 PUFA in this period. We evaluated the dietary n-3 PUFA intake and erythrocyte phospholipids n-3 PUFA in Chilean pregnant women. Eighty healthy pregnant women (20–36 years old) in the 3rd–6th month of pregnancy were included in the study. Dietary assessment was done ...
Tópico(s): Diet, Metabolism, and Disease
2014 - Multidisciplinary Digital Publishing Institute | Nutrients
Daniel Gonzalez‐Mañán, Gladys Tapia, Juan G. Gormaz, Amanda D’Espessailles, Alejandra Espinosa, Lilia Masson, Patricia Varela, Alfonso Valenzuela, Rodrigo Valenzuela,
High dietary intake of n-6 fatty acids in relation to n-3 fatty acids may generate health disorders, such as cardiovascular and other chronic diseases. Fish consumption rich in n-3 fatty acids is low in Latin America, it being necessary to seek other alternatives to provide α-linolenic acid (ALA), precursor of n-3 LCPUFA (EPA and DHA). Two innovative oils were assayed, chia (Salvia hispanica) and rosa mosqueta (Rosa rubiginosa). This study evaluated hepatic bioconversion of ALA to EPA and DHA, expression ...
Tópico(s): Lipid metabolism and biosynthesis
2012 - Royal Society of Chemistry | Food & Function
Adam H. Metherel, Rodrigo Valenzuela, Brinley J. Klievik, Giulia Cisbani, Ruxandra D. Rotarescu, Melissa González-Soto, Céline Cruciani‐Guglielmacci, Sophie Layé, Chr̀istophe Magnan, David M. Mutch, Richard P. Bazinet,
DHA is abundant in brain where it regulates cell survival, neurogenesis and neuroinflammation. DHA can be obtained from the diet or synthesized from alpha-linolenic acid (ALA; 18:3n-3) via a series of desaturation and elongation reactions occurring in the liver. Tracer studies suggest that dietary DHA can downregulate its own synthesis, but the mechanism remains undetermined and is the primary objective of this paper. First, we show by tracing 13C content (δ13C) of DHA via compound-specific isotope ...
Tópico(s): Lipid metabolism and biosynthesis
2024 - Elsevier BV | Journal of Lipid Research
Catherine Sánchez, Eliana Andahur, Rodrigo Valenzuela, Enrique A. Castellón, Juan Fullá, Christian G. Ramos, Juan Carlos Triviño,
... A. Sánchez 1 , Eliana I. Andahur 1,2 , Rodrigo Valenzuela 3 , Enrique A. Castellón 3 , Juan A. Fullá ...
Tópico(s): Circular RNAs in diseases
2015 - Impact Journals LLC | Oncotarget
Alfonso Valenzuela B, Rodrigo Valenzuela B,
INTRODUCCIÓNLos beneficios derivados del consumo habitual de los ácidos grasos omega-3 de origen marino están suficientemente documentados con sólida y abundante literatura científica que respalda su efectividad (1).Estos ácidos grasos son principalmente el ácido eicosapentaenoico (C20:5, EPA) y el ácido docosahexaenoico (C22:6, DHA).Originalmente, se atribuyó al EPA, a través de su transformación en diferentes eicosanoides (compuestos derivados de 20 átomos de carbono), los beneficios cardiovasculares ( ...
Tópico(s): Fatty Acid Research and Health
2014 - | Revista chilena de nutrición
Alfonso Valenzuela B, Rodrigo Valenzuela, Julio Sanhueza, Gladys Morales,
El mayor desarrollo economico y las mayores expectativas de vida de la poblacion, motivan una mayor preocupacion por la salud y la alimentacion a importantes grupos de la poblacion. Estos cambios han motivado el desarrollo de los llamados alimentos funcionales (AF) y de los nutraceuticos (NT) y de los FOSHU (Food with Specific Health Uses) en varios paises del mundo, principalmente en aquellos de mayor desarrollo economico. AF y NT son conceptos diferentes. Los AF son alimentos a los cuales se les ...
Tópico(s): Consumer Attitudes and Food Labeling
2014 - | Revista chilena de nutrición
Produção Nacional
Revisado por pares
Bruno Mendes Roatt, Rodrigo Dian de Oliveira Aguiar‐Soares, Levi Eduardo Soares Reis, Jamille Mirelle de Oliveira Cardoso, Fernando Augusto Siqueira Mathias, Rory Cristiane Fortes de Brito, Sydnei Magno da Silva, Nelder F. Gontijo, Sidney de Almeida Ferreira, Jesús G. Valenzuela, Rodrigo Corrêa‐Oliveira, Rodolfo Cordeiro Giunchetti, Alexandre Barbosa Reis,
Herein, we evaluated the treatment strategy employing a therapeutic heterologous vaccine composed of antigens of Leishmania braziliensis associated with MPL adjuvant (LBMPL vaccine) for visceral leishmaniasis (VL) in symptomatic dogs naturally infected by Leishmania infantum. Sixteen dogs received immunotherapy with MPL adjuvant (n = 6) or with a vaccine composed of antigens of L. braziliensis associated with MPL (LBMPL vaccine therapy, n = 10). Dogs were submitted to an immunotherapeutic scheme consisting ...
Tópico(s): Trypanosoma species research and implications
2017 - Frontiers Media | Frontiers in Immunology
Lionel Valenzuela, Rodrigo Ortega Blu, Daniel Moscovici, Jeff Gow, Adeline Alonso Ugaglia, Radu Mihăilescu,
Sustainability in production and consumption is increasing in importance in many diverse industries worldwide. The wine industry is no exception. There are many wine-related eco-certifications that incorporate sustainability concepts; however, it is unknown to what extent wine consumers value such certifications in wine-producing countries such as Chile. An online survey was conducted in which 526 Chilean wine consumers were asked about their attitudes towards and willingness to pay for sustainably ...
Tópico(s): Economic and Environmental Valuation
2022 - Multidisciplinary Digital Publishing Institute | Sustainability
Ignacio Arias, José M. Cardemil, Eduardo Zarza, Loreto Valenzuela, Rodrigo Escobar,
Solar thermal technologies for power generation have become cost-effective, efficient, flexible, and play a prominent role in achieving low-carbon energy systems. Concentrated solar power is the main solar technology for large-scale power generation and can offer thermal energy storage capacity, delivering power to the grid with high reliability, high capacity factor and low cost. However, their operation is constrained by the maximum temperature allowable for the heat transfer fluids used (up to ...
Tópico(s): Adsorption and Cooling Systems
2022 - Elsevier BV | Renewable and Sustainable Energy Reviews
Aránzazu Román-San-Miguel, Nuria Sánchez-Gey Valenzuela, Rodrigo Elías Zambrano,
Desde que en diciembre de 2019 comenzó a ser noticia en España el nuevo virus que provocaba la enfermedad denominada COVID-19, la población empezó a demandar más información. Ante esta situación, se expandió gran cantidad de informaciones falsas con las que el periodismo ha tenido que convivir, llegando incluso a colarse en las propias agendas mediáticas. Se parte de estas hipótesis: H1) Con la llegada de noticias sobre la COVID-19 aumentó el número de fake news en los medios televisivos, H2) El ...
Tópico(s): Radio, Podcasts, and Digital Media
2022 - Forum XXI | Vivat Academia
Produção Nacional
Revisado por pares
Pablo Valdés-Badilla, Tomás Herrera-Valenzuela, Rodrigo Ramírez‐Campillo, Esteban Aedo–Muñoz, Eduardo Báez-San Martín, Alex Ojeda-Aravena, Bráulio Henrique Magnani Branco,
The aim of this systematic review was to analyse the studies centered on the effects of Olympic combat sports (OCS [i.e., boxing, fencing, judo, karate, taekwondo, wrestling]) on older adults’ physical-functional, physiological, and psychoemotional health status. The review comprised randomised-controlled trials with OCS interventions, including older adults (≥60 years), and measures of physical-functional, physiological, and/or psychoemotional health. The studies were searched through SCOPUS, PubMed/ ...
Tópico(s): Physical Education and Training Studies
2021 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health
Aránzazu Román-San-Miguel, Nuria Sánchez-Gey Valenzuela, Rodrigo Elías Zambrano,
Introducción: Desde que en diciembre de 2019 se empezara a hablar en España sobre el coronavirus que estaba afectando a China, los rumores y las noticias imprecisas poblaron el mundo. Cuando la enfermedad llegó a Europa, la proliferación de información se multiplicó. Desde que se decretara el Estado de Alarma, los bulos y las fake news han sido una constante, que se ha reflejado en las informaciones de los medios de comunicación. Metodología: En este trabajo se analizan las informaciones publicadas ...
Tópico(s): Journalism and Media Studies
2020 - University of La Laguna | Revista Latina de Comunicación Social
Fernanda Rodríguez-Rojas, Américo López-Marras, Paula S. M. Celis‐Plá, Pamela T. Muñoz, Enzo García-Bartolomei, Fernando Valenzuela, Rodrigo Orrego, Adoración Carratalá, José Luis Sánchez‐Lizaso, Claudio A. Sáez,
Seawater desalination via reverse osmosis (SWRO) is highlighted as one of the most feasible solutions for obtaining freshwater. However, brine produced by SWRO is generally discharged to the subtidal area potentially causing detrimental effects on benthic organisms. In this study, we evaluated for the first time, ecophysiological and cellular responses of brown macroalgae as diagnosis tools to assess environmental impacts of desalination, through transplantation experiments with the cosmopolitan ...
Tópico(s): Marine and coastal plant biology
2020 - Elsevier BV | Desalination
Produção Nacional
Revisado por pares
Diana A. Ahuatzin, Erick J. Corro, Armando Aguirre‐Jaimes, Jorge Valenzuela, Rodrigo M. Feitosa, Milton Cézar Ribeiro, Juan Carlos López‐Acosta, Rosamond Coates, Wesley Dáttilo,
Tópico(s): Ecology and Vegetation Dynamics Studies
2019 - Springer Science+Business Media | Biodiversity and Conservation
Evelyn Pardo, Claudia Cárcamo, Reinaldo Uribe-San Martín, Ethel Ciampi, Fabián Segovia‐Miranda, Cristobal Curkovic-Peña, Fabián Montecino, Christopher P. Holmes, Juan E. Tichauer, Eric Acuña, Francisco Osorio‐Barrios, M Delgado Castro, Priscilla Cortés, Claudia Oyanadel, David M. Valenzuela, Rodrigo Pacheco, Rodrigo Naves, Andrea Soza, Alfonso González,
Galectin-8 (Gal-8) is a member of a glycan-binding protein family that regulates the immune system, among other functions, and is a target of antibodies in autoimmune disorders. However, its role in multiple sclerosis (MS), an autoimmune inflammatory disease of the central nervous system (CNS), remains unknown. We study the consequences of Gal-8 silencing on lymphocyte subpopulations and the development of experimental autoimmune encephalitis (EAE), to then assess the presence and clinical meaning of ...
Tópico(s): Glycosylation and Glycoproteins Research
2017 - Public Library of Science | PLoS ONE
Cristián Valenzuela, Rodrigo Zuloaga, Matías Poblete‐Morales, Tamara Vera-Tobar, Luís Mercado, Rubén Avendaño‐Herrera, Juan Antonio Valdés, Alfredo Molina,
Skeletal muscle in mammals can express and secrete immune-related molecules during pathogen infection. Despite in fish is known that classical immune tissues participate in innate immunity, the role of skeletal muscle in this function is poorly understood. To determine the immunocompetence of fish skeletal muscle, juvenile fine flounder (Paralichthys adpersus) were challenged with Vibrio ordalii. Different Toll-like receptors, pro-inflammatory cytokines (TNFα, Il-1β, and IL-8), and immune-effector ...
Tópico(s): interferon and immune responses
2017 - Elsevier BV | Developmental & Comparative Immunology
Cristián Valenzuela, Rodrigo Zuloaga, Luís Mercado, Ingibjörg Eir Einarsdóttir, Björn Thrándur Björnsson, Juan Antonio Valdés, Alfredo Molina,
Chronic stress detrimentally affects animal health and homeostasis, with somatic growth, and thus skeletal muscle, being particularly affected. A detailed understanding of the underlying endocrine and molecular mechanisms of how chronic stress affects skeletal muscle growth remains lacking. To address this issue, the present study assessed primary (plasma cortisol), secondary (key components of the GH/IGF system, muscular proteolytic pathways, and apoptosis), and tertiary (growth performance) stress ...
Tópico(s): Invertebrate Immune Response Mechanisms
2017 - American Physiological Society | AJP Regulatory Integrative and Comparative Physiology
Janyra A. Espinoza, Karen Böhmwald, Pablo F. Céspedes, Roberto Gómez, Sebastián A. Riquelme, Claudia Cortés, Javier A. Valenzuela, Rodrigo Sandoval, Floria Pancetti, Susan M. Bueno, Claudia A. Riedel, Alexis M. Kalergis,
Respiratory syncytial virus (RSV) is the major cause of respiratory illness in infants worldwide. Neurologic alterations, such as seizures and ataxia, have been associated with RSV infection. We demonstrate the presence of RSV proteins and RNA in zones of the brain—such as the hippocampus, ventromedial hypothalamic nucleus, and brainstem—of infected mice. One month after disease resolution, rodents showed behavioral and cognitive impairment in marble burying (MB) and Morris water maze (MWM) tests. ...
Tópico(s): Bacterial Infections and Vaccines
2013 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Arturo Prado, Patricio Andrades, Stefan Danilla, Susana Benítez, Sergio Escobar Reyes, Gustavo Valenzuela, Rodrigo Guridi, Patricio Fuentes,
Background: The purposes of this study were to retrospectively compare the 1-, 5-, and 10-year cosmetic outcomes of full-face carbon dioxide laser resurfacing using the SilkTouch technology, and analyze its advantages, disadvantages, and long-term results. Methods: Photographic results of full-face carbon dioxide laser resurfacing were evaluated after 1, 5, and 10 years. Statistical analysis considered surgeon and patient satisfaction based on a predetermined cosmetic visual analogue scale. Patients ...
Tópico(s): Laser Applications in Dentistry and Medicine
2008 - Lippincott Williams & Wilkins | Plastic & Reconstructive Surgery
Rodrigo Valenzuela, Karla A. Bascuñán, Rodrigo Chamorro, Cynthia Barrera, Jorge Sandoval, Claudia Puigrredon, Gloria Parraguez, Paula Orellana, Valeria González, Alfonso Valenzuela,
α-Linolenic acid (ALA) is the precursor of docosahexaenoic acid (DHA) in humans, which is fundamental for brain and visual function. Western diet provides low ALA and DHA, which is reflected in low DHA in maternal milk. Chia oil extracted from chia (Salvia hispanica L.), a plant native to some Latin American countries, is high in ALA (up to 60%) and thereby is an alternative to provide ALA with the aim to reduce DHA deficits. We evaluated the modification of the fatty acid profile of milk obtained from ...
Tópico(s): Cholesterol and Lipid Metabolism
2015 - Multidisciplinary Digital Publishing Institute | Nutrients
Verónica Sambra, Francisca Echeverría, Alfonso Valenzuela, Raphaël Chouinard‐Watkins, Rodrigo Valenzuela,
The role of docosahexaenoic acid (DHA) and arachidonic acid (AA) in neurogenesis and brain development throughout the life cycle is fundamental. DHA and AA are long-chain polyunsaturated fatty acids (LCPUFA) vital for many human physiological processes, such as signaling pathways, gene expression, structure and function of membranes, among others. DHA and AA are deposited into the lipids of cell membranes that form the gray matter representing approximately 25% of the total content of brain fatty acids. ...
Tópico(s): Peroxisome Proliferator-Activated Receptors
2021 - Multidisciplinary Digital Publishing Institute | Nutrients
Consuelo Valle, Francisca Echeverría, Vilma Chávez, Rodrigo Valenzuela, Andrés Bustamante,
Abstract During frying, oils can deteriorate due to autoxidation and hydrolytic alterations, processes influenced by the oil's fatty acid composition (FAC) and antioxidant content. However, there are different techniques to improve fried food quality and reduce oil absorption. This review aims to assess existing literature on the interactions between frying methods, oil selection, and the chemical composition of foods. To achieve this goal, the article examines the impact of oil FAC, antioxidants, ...
Tópico(s): Dye analysis and toxicity
2024 - Wiley | Food Safety and Health
Juan Tapia, Andrés Valenzuela, Rodrigo Lara, Marta Gomez‐Barrero, Christoph Busch,
Selfie-based biometrics has great potential for a wide range of applications since, e.g. periocular verification is contactless and is safe to use in pandemics such as COVID-19, when a major portion of a face is covered by a facial mask. Despite its advantages, selfie-based biometrics presents challenges since there is limited control over data acquisition at different distances. Therefore, Super-Resolution (SR) has to be used to increase the quality of the eye images and to keep or improve the recognition ...
Tópico(s): Face recognition and analysis
2022 - Institute of Electrical and Electronics Engineers | IEEE Access
Fernando Valenzuela, Rodrigo Flores,
Monoclonal antibodies or fusion proteins, defined as biological drugs, have modified the natural history of numerous immune-mediated disorders, allowing the development of therapies aimed at blocking the pathophysiological pathways of the disease, providing greater efficacy and safety than conventional treatment strategies.Virtually all therapeutic proteins elicit an immune response, producing anti-drug antibodies (ADAs) against hypervariable regions of immunoglobulins.Immunogenicity against biological ...
Tópico(s): Drug-Induced Adverse Reactions
2021 - Elsevier BV | Clinics
Carmen Palazzi, Rodolfo Miralles, Claudio Cezar de Miranda, Saúl Valenzuela, Rodrigo Casassus, Hugo Santander, Guillermo Ormeño,
This study was conducted in order to determine the effects of two types of pillows on bilateral electromyographic (EMG) activity of the sternocleidomastoid muscles. The study was performed on 15 patients with myogenic cranio-cervical mandibular dysfunction (CMD) and 15 healthy subjects. EMG recordings at rest and during swallowing of saliva and maximal voluntary clenching were performed by placing surface electrodes on the right and left sternocleidomastoid muscles. EMG activity was recorded in the ...
Tópico(s): Temporomandibular Joint Disorders
1999 - Taylor & Francis | CRANIO®
Rodrigo Valenzuela B, Karla Bascuñan G, Alfonso Valenzuela B, Rodrigo Chamorro M,
INTRODUCCIÓNEn las últimas tres décadas las enfermedades psiquiátricas y neurodegenerativas han experimentado un importante crecimiento, particularmente en los países de occidente.Reportes oficiales de las autoridades de salud de los Estados Unidos de América indican que estas patologías cada vez son más recurrentes en determinados grupos de riesgo (1-2
Tópico(s): Diet and metabolism studies
2009 - | Revista chilena de nutrición
Victoria Carrizo, Cristián Valenzuela, Rodrigo Zuloaga, Camila Aros, Claudia Altamirano, Juan Antonio Valdés, Alfredo Molina,
Salmonids are a species of high commercial value in Chilean aquaculture, where muscle is the final product of the industry. Fish can be affected by stress during intensive cultures, increasing susceptibility to infections. Recently, we reported that muscle is an important focus of immune reactions. However, studies have shown the immunosuppressive effect of stress only in lymphoid organs, and few studies have been conducted on muscle and immunity. Hence, we determine the effects of cortisol on the ...
Tópico(s): Physiological and biochemical adaptations
2021 - Elsevier BV | Veterinary Immunology and Immunopathology
Produção Nacional
Revisado por pares
Angie Vanessa Caicedo-Paz, Cassamo U. Mussagy, Victoria Mesa, Rodney H. Miotti, Rodrigo Valenzuela, Ariela Veloso de Paula, Julián Paúl Martínez Galán,
The present study describes an efficient and sustainable synthesis method for producing functional triglycerides (FTs) by conducting an acidolysis reaction of sacha inchi (Plukenetia volubilis) oil with capric acid (C10), catalyzed by Rhizopus oryzae (RO) lipase immobilized in low-cost corn cob powder, to obtain medium-large-medium chain (MLM) triglycerides. Initially, acidolysis reactions were performed between sacha inchi oil, C10, and the immobilized enzyme in a stirred tank at various temperatures ( ...
Tópico(s): Lipid metabolism and biosynthesis
2024 - Elsevier BV | Food Bioscience