Produção Nacional
Revisado por pares
Luís Gustavo Modelli de Andrade, Tainá Veras de Sandes‐Freitas, Lúcio Requião‐Moura, Laila Almeida Viana, Marina Pontello Cristelli, Valter Duro Garcı́a, Aline Lima Cunha Alcântara, Ronaldo de Matos Esmeraldo, Mário Abbud‐Filho, Álvaro Pacheco‐Silva, Érika Cristina Ribeiro de Lima Carneiro, Roberto Ceratti Manfro, Kellen Micheline Alves Henrique Costa, Denise Rodrigues Simão, Marcos Vinícius de Sousa, Viviane Brandão Bandeira de Mello Santana, Irene L. Noronha, Elen Almeida Romão, Juliana Aparecida Zanocco, Gustavo Guilherme Queiroz Arimatea, Deise De Boni Monteiro de Carvalho, Hélio Tedesco‐Silva, José Medina‐Pestana,
This analysis, using data from the Brazilian kidney transplant (KT) COVID-19 study, seeks to develop a prediction score to assist in COVID-19 risk stratification in KT recipients. In this study, 1379 patients (35 sites) were enrolled, and a machine learning approach was used to fit models in a derivation cohort. A reduced Elastic Net model was selected, and the accuracy to predict the 28-day fatality after the COVID-19 diagnosis, assessed by the area under the ROC curve (AUC-ROC), was confirmed in ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2021 - Elsevier BV | American Journal of Transplantation
Produção Nacional
Revisado por pares
J.C.T. Carvalho, Maria João Silva, Maria Aparecida Medeiros Maciel, Ângelo da Cunha Pinto, Domingos Sávio Nunes, Ronaldo Lima, Jairo K. Bastos, S J Sarti,
The anti-inflammatory and antinociceptive effects of trans-dehydrocrotonin, isolated from the bark of Croton cajucara (Euphorbiaceae), were investigated using several animal models. The trans-dehydrocrotonin produced a significant inhibition of carrageenin-induced paw edema and cotton pellet granuloma in rats. It also inhibited the writhings in mice induced by acetic acid, but did not show a significant effect in the hot-plate test in mice. The LD50 of t-DCTN was 555.0 mg/kg (p.o.) for mice.
Tópico(s): Traditional and Medicinal Uses of Annonaceae
1996 - Thieme Medical Publishers (Germany) | Planta Medica
Produção Nacional
Revisado por pares
José Fernando Bastos de Moura, José Maurício Mota, Caio A. Leite, Deysi Viviana Tenazoa Wong, Nilfácio Prado Bezerra, Gerly Anne de Castro Brito, Vilma Lima, Fernando Q. Cunha, Ronaldo A. Ribeiro,
To design a novel model to study Cobalt-60 (Co-60)-induced radiation mucositis and to describe the pathways involved in its development.Hamsters' cheeks were treated with Co-60 radiation (10, 20, 30 or 35 Gy). Three days later, oral mucosa scarification was performed with a needle. The animals were euthanized at day 13 (D + 13) after irradiation. Gross and microscopic alterations were evaluated by a new score system that we developed. Also, neutrophil infiltration, tumor necrosis factor-α (TNF-α), interleukin ( ...
Tópico(s): Effects of Radiation Exposure
2015 - Taylor & Francis | International Journal of Radiation Biology
Produção Nacional
Revisado por pares
Caio A. Leite, Viviane Teixeira Loiola de Alencar, Davi L.R. Melo, José Maurício Mota, Paulo H. Melo, Lívia Talita Cajaseiras Mourão, Deysi Viviana Tenazoa Wong, Pedro Jorge Caldas Magalhães, Armênio Aguiar dos Santos, Gerly Anne de Castro Brito, Roberto César Pereira Lima‐Júnior, Fernando Q. Cunha, Ronaldo A. Ribeiro,
Hemorrhagic cystitis is an important dose limiting side effect of ifosfamide based cancer chemotherapy. Despite chemoprophylaxis inflammation can still be found in cystoscopy guided biopsies. Previous studies confirmed the role of TNF-α and IL-1β. We evaluated the protective effect of the IL-1R antagonist anakinra and the anti-TNF-α antibody infliximab in experimental ifosfamide induced hemorrhagic cystitis.Hemorrhagic cystitis was induced by an injection of ifosfamide (400 mg/kg intraperitoneally) ...
Tópico(s): Chemotherapy-induced organ toxicity mitigation
2015 - Lippincott Williams & Wilkins | The Journal of Urology
Produção Nacional
Revisado por pares
José Bento Pereira Lima, Marcella Pereira da-Cunha, Ronaldo Carneiro da Silva, Allan Kardec Ribeiro Galardo, Sidinei da Silva Soares, Ima Aparecida Braga, RICARDO PIMENTEL RAMOS, Denise Valle,
Chemical insecticides have been widely used in Brazil for several years. This exposes mosquito populations to an intense selection pressure for resistance to insecticides. In 1999, the Brazilian National Health Foundation started the first program designed to monitor the resistance of Aedes aegypti to insecticides. We analyzed populations from 10 municipalities (from 84 selected in Brazil) in the states of Rio de Janeiro and Espírito Santo. Exposure of larvae to a diagnostic dose of temephos showed ...
Tópico(s): Insect Pest Control Strategies
2003 - American Society of Tropical Medicine and Hygiene | American Journal of Tropical Medicine and Hygiene
Produção Nacional
Revisado por pares
Ana Lorena Lima Ferreira, Ronaldo Fernandes Santos Alves, Amanda C. Cunha Figueiredo, Nadya Helena Alves‐Santos, Nathalia Freitas-Costa, Mônica Araújo Batalha, Chloe Yonemitsu, Nadia Manivong, Annalee Fürst, Lars Bode, Gilberto Kac,
Human milk oligosaccharide (HMO) composition varies throughout lactation and can be influenced by maternal characteristics. This study describes HMO variation up to three months postpartum and explores the influences of maternal sociodemographic and anthropometric characteristics in a Brazilian prospective cohort. We followed 101 subjects from 28-35 gestational weeks (baseline) and throughout lactation at 2-8 (visit 1), 28-50 (visit 2) and 88-119 days postpartum (visit 3). Milk samples were collected ...
Tópico(s): Neonatal Respiratory Health Research
2020 - Multidisciplinary Digital Publishing Institute | Nutrients
Produção Nacional
Revisado por pares
Rafael Telles, Ronaldo Alves da Cunha, André Lima Yoshimura, Alberto Castro Pochini, Benno Ejnisman, Renato Rozenblit Soliaman,
Throwing athletes present alterations in shoulder rotation range of motion (ROM), but not much is known about the relationship between these alterations and performance measurements in volleyball practitioners.To compare the passive ranges of motion of internal rotation (IR), external rotation (ER), and total rotation motion (TRM) of the shoulder in dominant and nondominant limbs of young volleyball athletes and to investigate their relationship with ball speed during serves with and without precision ( ...
Tópico(s): Sports Performance and Training
2021 - | International Journal of Sports Physical Therapy
Produção Nacional
Revisado por pares
Ronaldo A. Ribeiro, Mariana Lima Vale, S. H. Ferreira, Fernando Q. Cunha,
Tumor necrosis factor α (TNF-α) may have a pivotal role in the genesis of mechanical inflammatory hyperalgesia in rats and in the nociceptive writhing response in mice. Thalidomide has been shown to selectively inhibit TNF-α production. We therefore investigated the effect of thalidomide on these responses as well as on the hot plate response in mice. Hyperalgesic responses to intraplantar (i.pl.) injections of carrageenin or bradykinin, which act by stimulating TNF-α release, but not responses to ...
Tópico(s): Intramuscular injections and effects
2000 - Elsevier BV | European Journal of Pharmacology
Produção Nacional
Revisado por pares
Wallyson Amaral de Almeida, Laila Lima, Verusca Najara Cunha, Rafael Cunha, Ronaldo C. Araújo, Carlos Castilho Barros, Herbert Gustavo Simões, Carmen Sílvia Grubert Campbell,
Obesity is a highly prevalent condition associated with several diseases. Physical exercise has been considered as a non-pharmacological tool in the treatment of obesity. However, several aspects underlying exercise evaluation and prescription in obesity and associated pathologies are still under investigation. Although many research involving exercise have been performed in animal models, there is a lack of protocols for aerobic capacity assessment in obese animals, such as the ob/ob mice. This ...
Tópico(s): Pharmacological Effects and Assays
2011 - Wiley | Cell Biochemistry and Function
Produção Nacional
Paulo da Cunha Lana, Ronaldo Adriano Christofoletti, Joao B. Gusmao, Thayanne Lima Barros, Daphne Spier, Tânia Márcia Costa, Abílio Soares Gomes, Cinthya Simone Gomes Santos,
We assess the current knowledge of the benthic assemblages in the Southeastern Brazil Marine Ecoregion (SBME), which extends for approximately 1200 km of coastline and includes seven major estuarine systems from Guanabara Bay in Rio de Janeiro to Babitonga Bay (or São Francisco do Sul) in Santa Catarina. The high ecosystem diversity of SBME putatively accounts for the high levels of endemism of the regional marine invertebrate fauna. However, until more taxonomical and biogeographical evidence is ...
Tópico(s): Marine and coastal plant biology
2018 - Springer International Publishing | Brazilian marine biodiversity
Produção Nacional
Revisado por pares
Antoniella S. Gomes, Gemima G. Gadelha, Samara J. Lima, Joyce A. Garcia, Jand Venes Rolim Medeiros, Alexandre Havt, Aldo Â. M. Lima, Ronaldo A. Ribeiro, Gerly Anne de Castro Brito, Fernando Q. Cunha, Marcellus Henrique Loiola Ponte de Souza,
Our objective was to evaluate the role of heme-oxygenase 1 (HO-1)/biliverdin/CO pathway in gastric defense against ethanol-induced gastric damage in mice. Mice were pre-treated with saline, hemin (HO-1 inducer), biliverdin (HO-1 product), dimanganese decacarbonyl (DMDC, CO donor) or zinc protoporphyrin IX (ZnPP IX, HO-1 antagonist). Another group received soluble guanylate cyclase (sGC) inhibitor (ODQ) 30 min before hemin, biliverdin or DMDC. After 30 min, gastric damage was induced by ethanol. After one ...
Tópico(s): Cannabis and Cannabinoid Research
2010 - Elsevier BV | European Journal of Pharmacology
Produção Nacional
Revisado por pares
Diocésio Alves Pinto de Andrade, Vinícius Duval da Silva, Graziela De Luca Canto, Marcos Alves de Lima, Marcelo Vieira, Carlos Eduardo Mattos Cunha Andrade, Ronaldo Luís Schmidt, Rui Manuel Reis, Ricardo dos Reis,
Background Endometrial cancer presents well-defined risk factors: myometrial invasion, histological subtype, tumor grade, lymphovascular space invasion (LVSI). Some low and intermediate-risk endometrioid endometrial cancer patients exhibited unexpected outcomes. This study aimed to investigate other clinical-pathological factors that might influence the recurrence rates of patients diagnosed with low and intermediate-risk endometrioid endometrial cancer. Methods A case-control study from a cohort ...
Tópico(s): Estrogen and related hormone effects
2019 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Gerly Anne de Castro Brito, Daniela Sachs, Fernando Q. Cunha, Mariana Lima Vale, Celina M.C. Lotufo, Sérgio H. Ferreira, Ronaldo A. Ribeiro,
The aim of the present study was to determine the effect of pertussis toxin (PTX) on inflammatory hypernociception measured by the rat paw pressure test and to elucidate the mechanism involved in this effect. In this test, prostaglandin E(2) (PGE(2)) administered subcutaneously induces hypernociception via a mechanism associated with neuronal cAMP increase. Local intraplantar pre-treatment (30 min before), and post-treatment (5 min after) with PTX (600 ng/paw1, in 100 microL) reduced hypernociception ...
Tópico(s): Botulinum Toxin and Related Neurological Disorders
2006 - Wiley | European Journal of Neuroscience
Produção Nacional
Revisado por pares
Antoniella S. Gomes, Lívia M.F. Lima, Camila Linhares dos Santos, Fernando Q. Cunha, Ronaldo A. Ribeiro, Marcellus Henrique Loiola Ponte de Souza,
The effect of lipopolysaccharide (LPS) in gastric protection has not been elucidated, but ATP-sensitive potassium (KATP) channels are known to be involved in gastric defense. We evaluated the effect of LPS administration on indomethacin-induced gastropathy, and the role of KATP channels in this event. Rats received intravenous (i.v.) LPS administration. After 1/2, 6, 24 or 48 h, indomethacin was injected. 3 h later, gastric damage and myeloperoxidase activity were determined. Another group received ...
Tópico(s): Cardiac Ischemia and Reperfusion
2006 - Elsevier BV | European Journal of Pharmacology
Produção Nacional
Revisado por pares
Luís Carlos Barbosa Silva, Cinthya Rafaella Magalhães da Nóbrega Novaes, Ronaldo Alexandre de Lima Júnior, Bruno Barbosa Giudicelli, Arnaldo Tenório da Cunha Júnior, Maria Cecília Marinho Tenório, Clarice Martins, Rafael Miranda Tassitano,
Social isolation was adopted as a strategy to reduce the transmission speed of the severe acute respiratory syndrome of coronavirus 2 (SARS-CoV-2) in several countries in the world, including Brazil. As a result, schools were closed and the routines of children altered, affecting sleep, sedentary behavior, and physical activity. The present study aims to compare the children’s weekly routine and time spent on sleep, sedentary behavior and physical activity before and during the Coronavirus disease ...
Tópico(s): Health, Education, and Aging
2020 - Sociedade Brasileira de Atividade Física & Saúde | Revista Brasileira de Atividade Física & Saúde
Produção Nacional
Revisado por pares
Larisse T. Lucetti, Renan O. Silva, Ana Paula M. Santana, Bruno de Melo Tavares, Mariana Lima Vale, Pedro Marcos Gomes Soares, Francisco José Batista de Lima Júnior, Pedro Jorge Caldas Magalhães, Fernando Q. Cunha, Ronaldo de Albuquerque Ribeiro, Jand Venes Rolim Medeiros, Marcellus Henrique Loiola Ponte de Souza,
Tópico(s): Mast cells and histamine
2016 - Springer Science+Business Media | Digestive Diseases and Sciences
Produção Nacional
Revisado por pares
Gerly Anne de Castro Brito, Sandra Saraiva, João L. A. A. Falcão, Mariana Lima Vale, Aldo Â. M. Lima, Fernando Q. Cunha, Ronaldo A. Ribeiro,
The intraperitoneal injection of agents that increase the intracellular level of cyclic AMP (cAMP), reduced significantly the number of writhes induced by acetic acid and zymosan in mice. However, dibutyryl cyclic AMP (Db-cAMP) induced a dual response: (a) low doses caused antinociception, and (b) a high dose potentiated the nociceptive effect of a low concentration of acetic acid. High doses of Db-cAMP also reversed the antinociceptive effect of dexamethasone and the depletion of resident peritoneal ...
Tópico(s): Receptor Mechanisms and Signaling
2001 - Elsevier BV | European Journal of Pharmacology
Produção Nacional
Revisado por pares
Francisco Macedo, Lívia Talita Cajaseiras Mourão, H. Freitas, Roberto César Pereira Lima‐Júnior, Deysi Viviana Tenazoa Wong, Reinaldo B. Oriá, Mariana Lima Vale, Gerly Anne de Castro Brito, Fernando Q. Cunha, Ronaldo A. Ribeiro,
Tópico(s): Chemotherapy-induced organ toxicity mitigation
2011 - Springer Science+Business Media | Inflammation
Produção Nacional
Revisado por pares
Maria Luísa Pereira de Melo, Gerly Anne de Castro Brito, Rudy C. Soares, Sarah B. L. M. Carvalho, Johan V. Silva, Pedro Marcos Gomes Soares, Mariana Lima Vale, Marcellus Henrique Loiola Ponte de Souza, Fernando Q. Cunha, Ronaldo A. Ribeiro,
Tópico(s): Neutropenia and Cancer Infections
2007 - Springer Science+Business Media | Cancer Chemotherapy and Pharmacology
Elizabeth Christina de Andrade Lima,
... grupo “Cunha Lima” através da biografia política de Ronaldo José da Cunha Lima. Este é aclamado e festejado como o “poeta Ronaldo” e considerado o “pai’ do “Maior São João ...
Tópico(s): Social and Political Issues
2013 - | Raízes Revista de Ciências Sociais e Econômicas
Produção Nacional
Revisado por pares
Ronaldo Gonçalves Morato, Jeffrey J. Thompson, Agustín Paviolo, J. Antonio de la Torre, Fernando Lima, Roy McBride, Rogério Cunha de Paula, Laury Cullen, Leandro Silveira, Daniel Luis Zanella Kantek, Emiliano Esterci Ramalho, Louise Maranhão, Mario Haberfeld, Dênis A. Sana, Rodrigo A. Medellín, Eduardo Carrillo, Víctor Montalvo, Octavio Monroy‐Vilchis, Paula Cruz, Anah T. A. Jácomo, Natália Mundim Tôrres, Giselle Bastos Alves, Ivonne Cassaigne, Ron Thompson, Carolina Saens‐Bolanos, Juan Carlos Hinojosa Cruz, Luiz D. Alfaro, Isabel Hagnauer, Xavier Marina da Silva, Alexandre Vogliotti, Marcela Figuerêdo Duarte Moraes, Selma Samiko Miyazaki, Thadeu Deluque Costa Pereira, Gediendson Ribeiro de Araújo, Leanes Cruz da Silva, Lucas Leuzinger, Marina Mouzinho Carvalho, Lilian Rampin, Leonardo Sartorello, Howard Quigley, Fernando Rodrigo Tortato, Rafael Hoogesteijn, Peter G. Crawshaw, Allison L. Devlin, Joares Adenílson May-Júnior, Fernando César Cascelli de Azevedo, Henrique Villas Boas Concone, Verónica Quiroga, Sebastián Andrés Costa, Juan Pablo Arrabal, Ezequiel Vanderhoeven, Yamil E. Di Blanco, Alexandre Martins Costa Lopes, Cynthia Elisa Widmer, Milton Cézar Ribeiro,
Abstract The field of movement ecology has rapidly grown during the last decade, with important advancements in tracking devices and analytical tools that have provided unprecedented insights into where, when, and why species move across a landscape. Although there has been an increasing emphasis on making animal movement data publicly available, there has also been a conspicuous dearth in the availability of such data on large carnivores. Globally, large predators are of conservation concern. However, ...
Tópico(s): Bat Biology and Ecology Studies
2018 - Wiley | Ecology
Produção Nacional
Revisado por pares
Jand Venes Rolim Medeiros, Victor Hugo Braz Bezerra, Antoniella S. Gomes, André Luiz dos Reis Barbosa, Roberto César Pereira Lima‐Júnior, Pedro Marcos Gomes Soares, Gerly Anne de Castro Brito, Ronaldo A. Ribeiro, Fernando Q. Cunha, Marcellus Henrique Loiola Ponte de Souza,
The aim of this study was to evaluate the protective effect of hydrogen sulfide (H 2 S) on ethanol-induced gastric lesions in mice and the influence of ATP-sensitive potassium (K ATP ) channels, capsaicin-sensitive sensory afferent neurons, and transient receptor potential vanilloid (TRPV) 1 receptors on such an effect. Saline and l-cysteine alone or with propargylglycine, sodium hydrogen sulfide (NaHS), or Lawesson9s reagent were administrated for testing purposes. For other experiments, mice were pretreated ...
Tópico(s): Neuroscience of respiration and sleep
2009 - American Society for Pharmacology and Experimental Therapeutics | Journal of Pharmacology and Experimental Therapeutics
Produção Nacional
Revisado por pares
Ronaldo A. Ribeiro, Mariana Lima Vale, Sara M. Thomazzi, Adriana B.P Paschoalato, Steve Poole, S. H. Ferreira, Fernando Q. Cunha,
Intraperitoneal administration of zymosan and acetic acid induced a dose-dependent nociceptive writhing response in mice. Lavage of the peritoneal cavities with saline reduced the number of total resident peritoneal cells and caused a proportional decrease in the nociceptive responses induced by these stimuli. Furthermore, the specific reduction of the peritoneal mast cell population by intraperitoneal administration of compound 48/80 also reduced the nociceptive responses induced by zymosan and ...
Tópico(s): Mast cells and histamine
2000 - Elsevier BV | European Journal of Pharmacology
Produção Nacional
Revisado por pares
Luís Mesquita Sousa-Filho, Cléverson D.T. Freitas, Marina Duarte Pinto Lobo, Ana Cristina de Oliveira Monteiro‐Moreira, Renan O. Silva, Lucas de Araújo Bastos Santana, Ronaldo A. Ribeiro, Marcellus Henrique Loiola Ponte de Souza, Gustavo Portela Ferreira, Anna Carolina Toledo da Cunha Pereira, André Luiz dos Reis Barbosa, Mauro Sérgio Cruz Souza Lima, Jefferson Soares de Oliveira,
Parotoid glands of amphibians are known for the production of several biologically active compounds having pharmacological and toxic effects in mammals. In the present work, a protein fraction obtained from Rhinella schneideri parotoid gland (RsPP) was characterized to study its biological and toxic effects. Rhinella schneideri parotoid secretion is composed of up to 30% (w/w) of soluble proteins. Tandem mass spectrometric analysis of the RsPP identified 104 proteins, including actin, beta-actin, ...
Tópico(s): Galectins and Cancer Biology
2016 - Wiley | Journal of Experimental Zoology Part A Ecological Genetics and Physiology
Produção Nacional
Revisado por pares
Ronaldo A. Ribeiro, Carlos W. Wanderley, Deysi Viviana Tenazoa Wong, José Maurício Mota, Caio A. Leite, Marcellus Henrique Loiola Ponte de Souza, Fernando Q. Cunha, Roberto César Pereira Lima‐Júnior,
Tópico(s): Neutropenia and Cancer Infections
2016 - Springer Science+Business Media | Cancer Chemotherapy and Pharmacology
Produção Nacional
Revisado por pares
Bruno da Silva Gomes, Benedito P.S. Neto, Everton Moraes Lopes, Francisco Valmor Macedo Cunha, Alyne Rodrigues de Araújo, Carlos W. Wanderley, Deysi Viviana Tenazoa Wong, Roberto César Pereira Lima Júnior, Ronaldo A. Ribeiro, Damião Pergentino de Sousa, Jand Venes Rolim Medeiros, Rita C. M. Oliveira, Francisco de Assis Oliveira,
Myrtenol is a bicyclic monoterpene with anti-inflammatory properties. However, the mechanisms involved are partially unknown. Here, we investigated the effect of myrtenol during experimental chronic arthritis and the possible modulating activity of oxidative stress and neutrophil migration. Complete Freund's Adjuvant (CFA)-sensitized rats were treated with vehicle (1 mL/kg, po), myrtenol (12.5, 25 or 50 mg/kg, po), indomethacin (10 mg/kg, po) or dexamethasone (0.4 mg/kg) followed by intra-articular injection ...
Tópico(s): Pharmacological Effects of Natural Compounds
2017 - Elsevier BV | Chemico-Biological Interactions
Produção Nacional
Revisado por pares
Andréa Camardella de Lima Rizzo, Renata da Matta dos Santos, Ronaldo Luiz Correa dos Santos, Adriana U. Soriano, Cláudia Duarte da Cunha, Alexandre Soares Rosado, Luis G. dos S. Sobral, Selma Gomes Ferreira Leite,
Abstract BACKGROUND: Oil spills are a frequent source of environmental contamination. As a consequence, remediation of soils, waters and sediments is a great challenge in this area of research. This study aims at using a new type of soil bioreactor (13 L bench‐scale and 800 L pilot‐scale) to treat tropical soil contaminated with petroleum. Additionally, it includes the evaluation of the effectiveness of two auxiliary techniques: bulking agent addition (sawdust) and biostimulation using two different ...
Tópico(s): Enhanced Oil Recovery Techniques
2010 - Wiley | Journal of Chemical Technology & Biotechnology
Produção Nacional
Revisado por pares
Handerson Rodrigues Silva Lima, Emanuel Airton de Oliveira Farias, Paulo Ronaldo Sousa Teixeira, Carla Eiras, Lívio César Cunha Nunes,
Tópico(s): Analytical Chemistry and Sensors
2019 - Springer Science+Business Media | Journal of Solid State Electrochemistry
Produção Nacional
Revisado por pares
Handerson Rodrigues Silva Lima, Josany Saibrosa da Silva, Emanuel Airton de Oliveira Farias, Paulo Ronaldo Sousa Teixeira, Carla Eiras, Lívio César Cunha Nunes,
Cancer is a leading cause of death worldwide, often being treated with antineoplastic drugs that have high potential for toxicity to humans and the environment, even at very low concentrations. Therefore, monitoring these drugs is of utmost importance. Among the techniques used to detect substances at low concentrations, electrochemical sensors and biosensors have been noted for their practicality and low cost. This review brings, for the first time, a simplified outline of the main electrochemical ...
Tópico(s): Electrochemical sensors and biosensors
2018 - Elsevier BV | Biosensors and Bioelectronics
Produção Nacional
Revisado por pares
Delane Viana Gondim, Joana Cláudia Bezerra de Araújo, André Luiz Cunha Cavalcante, Alexandre Havt, Josiane da Silva Quetz, Gerly Anne de Castro Brito, Ronaldo de Albuquerque Ribeiro, Mariana Lima Vale,
Electroacupuncture (EA) and cannabinoids have been reported to have anti-inflammatory and antinociceptive effects in animal models of arthritis. Male Wistar rats were injected with saline or zymosan (2 mg) into the temporomandibular joint (TMJ). EA (10 Hz, 30 min) was performed 2 h after or 1 h before zymosan administration. AM251 or AM630 (3 mg/kg, i.p.)were administered before EA treatment. Mechanical hypernociception was accessed after zymosan administration. Rats were sacrificed 6 h after zymosan ...
Tópico(s): Healthcare and Venom Research
2012 - NRC Research Press | Canadian Journal of Physiology and Pharmacology