Rosalinda Madonna, Carmela Rita Balistreri, Salvatore De Rosa, Saverio Muscoli, Stefano Selvaggio, Giancarlo Selvaggio, Péter Ferdinandy, Raffaele De Caterina,
Cardiovascular diseases (CVD) including coronary artery disease (CAD) and ischemic heart disease (IHD) are the main cause of mortality in industrialized countries. Although it is well known that there is a difference in the risk of these diseases in women and men, current therapy does not consider the sexual dimorphism; i.e., differences in anatomical structures and metabolism of tissues. Here, we discuss how genetic, epigenetic, hormonal, cellular or molecular factors may explain the different CVD ...
Tópico(s): Cardiovascular Disease and Adiposity
2019 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine
Sara Matricardi, Alberto Spalice, Vincenzo Salpietro, Gabriella Di Rosa, Maria Cristina Balistreri, Salvatore Grosso, Pasquale Parisi, Maurizio Elia, Pasquale Striano, Patrizia Accorsi, Raffaella Cusmai, Nicola Specchio, Giangennaro Coppola, Salvatore Savasta, Marco Carotenuto, E. Tozzi, Pietro Ferrara, Martino Ruggieri, Alberto Verrotti,
This paper reports on the clinical aspects, electroencephalographic (EEG) features, and neuroimaging findings in children with full trisomy 18 and associated epilepsy, and compares the evolution and outcome of their neurological phenotype. We retrospectively studied 18 patients (10 males and 8 females; aged 14 months to 9 years) with full trisomy 18 and epilepsy. All patients underwent comprehensive assessment including neuroimaging studies of the brain. We divided patients into two groups according ...
Tópico(s): Genetics and Neurodevelopmental Disorders
2016 - Wiley | American Journal of Medical Genetics Part C Seminars in Medical Genetics
Carmela Rita Balistreri, Claudia Leonarda Ammoscato, Letizia Scola, Tiziana Fragapane, Rosa Maria Giarratana, Domenico Lio, Maria Piccione,
Background: Congenital heart defects (CHDs) are present in about 40–60% of newborns with Down syndrome (DS). Patients with DS can also develop acquired cardiac disorders. Mouse models suggest that a critical 3.7 Mb region located on human chromosome 21 (HSA21) could explain the association with CHDs. This region includes a cluster of genes (IFNAR1, IFNAR2, IFNGR2, IL10RB) encoding for interferon receptors (IFN-Rs). Other genes located on different chromosomes, such as the vascular endothelial growth ...
Tópico(s): Congenital Heart Disease Studies
2020 - Multidisciplinary Digital Publishing Institute | Genes
Caterina Mian, Gianmaria Pennelli, Matteo Fassan, Mariangela Balistreri, Susi Barollo, Elisabetta Cavedon, Francesca Galuppini, Marco Pizzi, Federica Vianello, Maria Rosa Pelizzo, M. E. Girelli, Massimo Rugge, Giuseppe Opocher,
MicroRNAs (miRNAs) are involved in the pathogenesis of human cancers, including medullary thyroid carcinoma (MTC). The aim of this study was to test the hypothesis that different miRNA profiles are related to RET status and prognosis in patients with hereditary MTC (hMTC) and sporadic MTC (sMTC).We analyzed the expression of nine miRNAs (miR-21, miR-127, miR-154, miR-224, miR-323, miR-370, miR-9*, miR-183, and miR-375) by quantitative real-time-polymerase chain reaction in 34 cases of sMTC, 6 cases of ...
Tópico(s): Thyroid Cancer Diagnosis and Treatment
2012 - Mary Ann Liebert, Inc. | Thyroid
A. Allegra, Rosa Maria Giarratana, Letizia Scola, Carmela Rita Balistreri,
The research on neurodegenerative diseases (NeuroDegD) has been traditionally focused on later life stages. There is now an increasing evidence, that they may be programmed during early development. Here, we propose that NeuroDegD are the result of the complex process of imprinting on fetal hemogenic endothelium, from which the microglial cells make to origin. The central role of placenta and epigenetic mechanisms (methylation of DNA, histone modifications and regulation by non-coding RNAs) in mediating ...
Tópico(s): Birth, Development, and Health
2021 - Elsevier BV | Mechanisms of Ageing and Development
Letizia Scola, Rosa Maria Giarratana, Salvatore Torre, Vincenzo Argano, Domenico Lio, Carmela Rita Balistreri,
The need to facilitate the complex management of cardiometabolic diseases (CMD) has led to the detection of many biomarkers, however, there are no clear explanations of their role in the prevention, diagnosis or prognosis of these diseases. Molecules associated with disease pathways represent valid disease surrogates and well-fitted CMD biomarkers. To address this challenge, data from multi-omics types (genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiomics, and nutrigenomics), ...
Tópico(s): Adipose Tissue and Metabolism
2019 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Produção Nacional
Revisado por pares
Antonio Vitale, Valeria Caggiano, Maria Cristina Maggio, Giuseppe Lopalco, Giacomo Emmi, Jurgen Sota, Francesco La Torre, Piero Ruscitti, Elena Bartoloni, Giovanni Conti, Claudia Fabiani, Irene Mattioli, Carla Gaggiano, Fabio Cardinale, Lorenzo Dagna, Corrado Campochiaro, Roberto Giacomelli, Alberto Balistreri, Katerina Laskari, Abdurrahman Tufan, Gaafar Ragab, Ibrahim Almaghlouth, Ewa Więsik–Szewczyk, Rosa Maria Rodrigues Pereira, Bruno Frediani, Florenzo Iannone, Petros P. Sfikakis, Luca Cantarini,
Interleukin (IL)-1 inhibitors are largely employed in patients with Still's disease; in cases with refractory arthritis, IL-6 inhibitors have shown to be effective on articular inflammatory involvement. The aim of the present study is to assess any difference in the effectiveness of the IL-1β antagonist canakinumab prescribed as first-line biologic agent between the systemic and the chronic-articular Still's disease.Data were drawn from the retrospective phase of the AutoInflammatory Disease Alliance ( ...
Tópico(s): Musculoskeletal synovial abnormalities and treatments
2022 - Frontiers Media | Frontiers in Medicine
Domenico Lio, Letizia Scola, Rosa Maria Giarratana, Giuseppina Candore, Giuseppina Colonna‐Romano, Calogero Caruso, Carmela Rita Balistreri,
Like other infectious diseases, COVID-19 shows a clinical outcome enormously variable, ranging from asymptomatic to lethal. In Italy, like in other countries, old male individuals, with one or more comorbidity, are the most susceptible group, and show, consequently, the highest mortality, and morbidity, including lethal respiratory distress syndrome, as the most common complication. In addition, another extraordinary peculiarity, that is a surprising resistance to COVID-19, characterizes some Italian ...
Tópico(s): Diabetes and associated disorders
2021 - Elsevier BV | Ageing Research Reviews
Davide Vacca, Antonino Fiannaca, Fabio Tramuto, Valeria Cancila, Laura La Paglia, Walter Mazzucco, Alessandro Gulino, Massimo La Rosa, Carmelo Massimo Maida, Gaia Morello, Beatrice Belmonte, Alessandra Casuccio, Rosario Maugeri, Gerardo Iacopino, Carmela Rita Balistreri, Francesco Vitale, Claudio Tripodo, Alfonso Urso,
In consideration of the increasing prevalence of COVID-19 cases in several countries and the resulting demand for unbiased sequencing approaches, we performed a direct RNA sequencing (direct RNA seq.) experiment using critical oropharyngeal swab samples collected from Italian patients infected with SARS-CoV-2 from the Palermo region in Sicily. Here, we identified the sequences SARS-CoV-2 directly in RNA extracted from critical samples using the Oxford Nanopore MinION technology without prior cDNA ...
Tópico(s): SARS-CoV-2 detection and testing
2022 - Multidisciplinary Digital Publishing Institute | Life
Letizia Scola, Rosa Maria Giarratana, Vincenzo Marinello, Valeria Cancila, Calogera Pisano, Giovanni Ruvolo, Giacomo Frati, Domenico Lio, Carmela Rita Balistreri,
Background: Previous studies have demonstrated that polymorphisms involved in immune genes can affect the risk, pathogenesis, and outcome of thoracic ascending aortic aneurysms (TAAA). Here, we explored the potential associations of five functional promoter polymorphisms in interleukin-6 (IL-6), IL-1B, IL-1A, IL-18, and Tumor necrosis factor (TNF)A genes with TAAA. Methods: 144 TAAA patients and 150 age/gender matched controls were typed using KASPar assays. Effects on telomere length and levels of ...
Tópico(s): Infectious Aortic and Vascular Conditions
2021 - Multidisciplinary Digital Publishing Institute | Biomolecules
Dario Buccheri, Calogera Pisano, Davide Piraino, Bernardo Cortese, Paola Rosa Chirco, Gregory Dendramis, Carmela Rita Balistreri, Giuseppe Andolina, Vincenzo Argano, Giovanni Ruvolo,
<p>Coronary artery fistulas are rare anatomic abnormalities of the coronary arteries present in 0.002% of the general population and represent 14% of all anomalies of coronary arteries. Their clinical relevance focuses mainly on the mechanism of "coronary steal phenomenon”, causing myocardial functional ischemia even in the absence of stenosis, hence common symptoms are angina or dyspnea. Small size fistulas are mostly asymptomatic and have excellent prognosis if managed medically with regular ...
Tópico(s): Cardiac Arrhythmias and Treatments
2015 - Barcaray International | International Cardiovascular Forum Journal
caterina mian, Gianmaria Pennelli, Matteo Fassan, Mariangela Balistreri, Susi Barollo, Elisabetta Cavedon, Francesca Galuppini, Marco Pizzi, federica vianello, Maria Rosa Pelizzo, Marialisa Girelli, Massimo Rugge, Giuseppe Opocher,
Background: MicroRNAs (miRNAs) are involved in the pathogenesis of human cancers, including medullary thyroid carcinoma (MTC).The aim of this study was to test the hypothesis that different miRNA profiles are related to RET status and prognosis in patients with hereditary MTC (hMTC) and sporadic MTC (sMTC).Methods: We analyzed the expression of nine miRNAs (miR-21, miR-127, miR-154, miR-224, miR-323, miR-370, miR-9*, miR-183, and miR-375) by quantitative real-time-polymerase chain reaction in 34 cases ...
Tópico(s): MicroRNA in disease regulation
2012 - Mary Ann Liebert, Inc. | Thyroid
Produção Nacional
Revisado por pares
Francesca Della Casa, Antonio Vitale, Silvana Guerriero, Jurgen Sota, Rolando Cimaz, Gaafar Ragab, Piero Ruscitti, Rosa Maria Rodrigues Pereira, Francesca Minoia, Emanuela Del Giudice, Giacomo Emmi, Claudia Lomater, Sara Monti, Claudia Canofari, Carla Gaggiano, Giovanni Alessio, Elisabetta Miserocchi, Alessandro Conforti, Marilia Ambiel Dagostin, Chiara Mapelli, Maria Pia Paroli, Veronica Parretti, Valeria Albano, Rosa Anna Favale, Luca Marelli, Mohamed Tharwat Hegazy, Paola Cipriani, Isabele P. B. Antonelli, Valeria Caggiano, Emma Aragona, Ahmed Hatem Laymouna, Gian Marco Tosi, Maria Tarsia, Marco Cattalini, Francesco La Torre, Giuseppe Lopalco, Ewa Więsik–Szewczyk, Micol Frassi, Stefano Gentileschi, Heitor F. Giordano, Bruno Frediani, Samuel Katsuyuki Shinjo, Donato Rigante, Petros P. Sfikakis, Alberto Balistreri, Mohamed Hussein, Rana Hussein Amin, Luca Cantarini, Claudia Fabiani,
The aim of this paper is to point out the design, development and deployment of the AutoInflammatory Disease Alliance (AIDA) International Registry for paediatric and adult patients with non-infectious uveitis (NIU).This is a physician-driven, population- and electronic-based registry implemented for both retrospective and prospective collection of real-world demographics, clinical, laboratory, instrumental and socioeconomic data of patients with uveitis and other non-infectious inflammatory ocular ...
Tópico(s): Retinal Diseases and Treatments
2022 - Adis, Springer Healthcare | Ophthalmology and Therapy
... Pharmacol 1992; 43: 1969–74. 54 Suchy FJ, Balistreri WF, Hung J, Miller P, Garfield SA. Intracellular ... 2: 117–23. 61 Gotto AM Jr, La Rosa JC, Hunninghake D et al. The cholesterol facts. ...
Tópico(s): Amino Acid Enzymes and Metabolism
1996 - Wiley | European Journal of Clinical Investigation
Shashi Kumar Gupta, Claudia Bang, Thomas Thum,
... Belmonte B, Mango R, Scola L, Novelli G, Balistreri C and Sangiuolo F (2021) Genetic and Epigenetic ...
Tópico(s): Circular RNAs in diseases
2010 - Lippincott Williams & Wilkins | Circulation Cardiovascular Genetics
Produção Nacional
Revisado por pares
Antonio Vitale, Francesca Della Casa, Giuseppe Lopalco, Rosa Maria Rodrigues Pereira, Piero Ruscitti, Roberto Giacomelli, Gaafar Ragab, Francesco La Torre, Elena Bartoloni, Emanuela Del Giudice, Claudia Lomater, Giacomo Emmi, Marcello Govoni, Maria Cristina Maggio, Armin Maier, Joanna Makowska, Benson Ogunjimi, Petros P. Sfikakis, Paolo Sfriso, Carla Gaggiano, Florenzo Iannone, Marilia Ambiel Dagostin, Ilenia Di Cola, Luca Navarini, Ayman Abdel-Monem Ahmed Mahmoud, Fabio Cardinale, Ilenia Riccucci, Maria Pia Paroli, Elena Marucco, Irene Mattioli, Jurgen Sota, Anna Abbruzzese, Isabele P. B. Antonelli, Paola Cipriani, Abdurrahman Tufan, Claudia Fabiani, Mustafa Mahmoud Ramadan, Marco Cattalini, R. C. Kardaş, Gian Domenico Sebastiani, Henrique Ayres Mayrink Giardini, José Hernández‐Rodríguez, Violetta Mastrorilli, Ewa Więsik–Szewczyk, Micol Frassi, Valeria Caggiano, Salvatore Telesca, Heitor F. Giordano, Emmanuele Guadalupi, Teresa Giani, Alessandra Renieri, Sergio Colella, Giulia Cataldi, Martina Gentile, Alessandra Fabbiani, Ibrahim Almaghlouth, Bruno Frediani, Alberto Balistreri, Donato Rigante, Luca Cantarini,
Aim of this paper is to present the design, construction, and modalities of dissemination of the AutoInflammatory Disease Alliance (AIDA) International Registry for patients with systemic juvenile idiopathic arthritis (sJIA) and adult-onset Still's disease (AOSD), which are the pediatric and adult forms of the same autoinflammatory disorder.This Registry is a clinical, physician-driven, population- and electronic-based instrument implemented for the retrospective and prospective collection of real- ...
Tópico(s): Kawasaki Disease and Coronary Complications
2022 - Frontiers Media | Frontiers in Medicine
Produção Nacional
Revisado por pares
Antonio Vitale, Valeria Caggiano, Francesca Della Casa, José Hernández‐Rodríguez, Micol Frassi, Sara Monti, Abdurrahman Tufan, Salvatore Telesca, Edoardo Conticini, Gaafar Ragab, Giuseppe Lopalco, Ibrahim Almaghlouth, Rosa Maria Rodrigues Pereira, Derya Yıldırım, Marco Cattalini, Achille Marino, Teresa Giani, Francesco La Torre, Piero Ruscitti, Emma Aragona, Ewa Więsik–Szewczyk, Emanuela Del Giudice, Petros P. Sfikakis, Marcello Govoni, Giacomo Emmi, Maria Cristina Maggio, Roberto Giacomelli, Francesco Ciccia, Giovanni Conti, Djouher Ait‐Idir, Claudia Lomater, Vito Sabato, Matteo Piga, Ali Şahin, Daniela Opriș-Belinski, Ruxandra Ionescu, Elena Bartoloni, Franco Franceschini, Paola Parronchi, Amato de Paulis, Gerard Espinosa, Armin Maier, Gian Domenico Sebastiani, Antonella Insalaco, Farhad Shahram, Paolo Sfriso, Francesca Minoia, Maria Alessio, Joanna Makowska, Gülen Hatemi, Nurullah Akkoç, Francesca Li Gobbi, Antonio Gidaro, Alma Nunzia Olivieri, Sulaiman M. Al‐Mayouf, Şükran Erten, Stefano Gentileschi, İ. Vasi, Maria Tarsia, Ayman Abdel-Monem Ahmed Mahmoud, Bruno Frediani, Musa Alzahrani, Ahmed Hatem Laymouna, Francesca Ricci, Fabio Cardinale, Karina Jahnz‐Różyk, Gian Marco Tosi, Francesca Crisafulli, Alberto Balistreri, Marilia Ambiel Dagostin, Mahmoud Ghanema, Carla Gaggiano, Jurgen Sota, Ilenia Di Cola, Claudia Fabiani, Henrique Ayres Mayrink Giardini, Alessandra Renieri, Alessandra Fabbiani, Anna Carrer, Monica Bocchia, Federico Caroni, Donato Rigante, Luca Cantarini,
Objective The aim of this paper is to present the AutoInflammatory Disease Alliance (AIDA) international Registry dedicated to Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic (VEXAS) syndrome, describing its design, construction, and modalities of dissemination. Methods This Registry is a clinical, physician-driven, population- and electronic-based instrument designed for the retrospective and prospective collection of real-life data. Data gathering is based on the Research Electronic Data ...
Tópico(s): Coagulation, Bradykinin, Polyphosphates, and Angioedema
2022 - Frontiers Media | Frontiers in Medicine
Produção Nacional
Revisado por pares
Antonio Vitale, Francesca Della Casa, Gaafar Ragab, Ibrahim Almaghlouth, Giuseppe Lopalco, Rosa Maria Rodrigues Pereira, Silvana Guerriero, Marcello Govoni, Petros P. Sfikakis, Roberto Giacomelli, Francesco Ciccia, Sara Monti, Piero Ruscitti, Matteo Piga, Claudia Lomater, Abdurrahman Tufan, Daniela Opriș-Belinski, Giacomo Emmi, José Hernández‐Rodríguez, Ali Şahin, Gian Domenico Sebastiani, Elena Bartoloni, Nurullah Akkoç, Özgül Soysal Gündüz, Marco Cattalini, Giovanni Conti, Gülen Hatemi, Armin Maier, Paola Parronchi, Emanuela Del Giudice, Şükran Erten, Antonella Insalaco, Francesca Li Gobbi, Maria Cristina Maggio, Farhad Shahram, Valeria Caggiano, Mohamed Tharwat Hegazy, Kazi Nur Asfina, Maria Morrone, Leandro Lara do Prado, Rosanna Dammacco, Francesca Ruffilli, Aikaterini Arida, Luca Navarini, Ilenia Pantano, Lorenzo Cavagna, Alessandro Conforti, Alberto Cauli, Elena Marucco, Hamit Küçük, Ruxandra Ionescu, Irene Mattioli, Gerard Espinosa, Olga Araújo, Burak Karkaş, Claudia Canofari, Jurgen Sota, Ahmed Hatem Laymouna, Asma Bedaiwi, Sergio Colella, Henrique Ayres Mayrink Giardini, Valeria Albano, Andrea Lo Monaco, G. Fragoulis, R. C. Kardaş, Virginia Berlengiero, Mohamed Hussein, Francesca Ricci, Francesco La Torre, Donato Rigante, Ewa Więsik–Szewczyk, Micol Frassi, Stefano Gentileschi, Gian Marco Tosi, Marilia Ambiel Dagostin, Ayman Abdel-Monem Ahmed Mahmoud, Maria Tarsia, Giovanni Alessio, Rolando Cimaz, Teresa Giani, Carla Gaggiano, Florenzo Iannone, Paola Cipriani, Mariam Mourabi, Veronica Spedicato, Sara Barneschi, Emma Aragona, Alberto Balistreri, Bruno Frediani, Claudia Fabiani, Luca Cantarini,
Abstract Purpose of the present paper is to point out the design, development and deployment of the AutoInflammatory Disease Alliance (AIDA) International Registry dedicated to pediatric and adult patients with Behçet’s disease (BD). The Registry is a clinical physician-driven non-population- and electronic-based instrument implemented for the retrospective and prospective collection of real-life data about demographics, clinical, therapeutic, laboratory, instrumental and socioeconomic information ...
Tópico(s): Retinal and Optic Conditions
2022 - Springer Science+Business Media | Internal and Emergency Medicine
Produção Nacional
Revisado por pares
Jurgen Sota, Antonio Vitale, Giuseppe Lopalco, Rosa Maria Rodrigues Pereira, Heitor F. Giordano, Isabele P. B. Antonelli, Joanna Makowska, Olga Brzezińska, Anna Lewandowska‐Polak, Piero Ruscitti, Paola Cipriani, Ilenia Di Cola, Marcello Govoni, Francesca Ruffili, Petros P. Sfikakis, Katerina Laskari, Gaafar Ragab, Mohamed Hussein, Stefano Gentileschi, Carla Gaggiano, Francesco La Torre, Armin Maier, Giacomo Emmi, Achille Marino, Francesco Ciccia, Paolo Sfriso, Maria Cristina Maggio, Elena Bartoloni, Claudia Lomater, Mohamed Tharwat Hegazy, Maria G. Tektonidou, Marilia Ambiel Dagostin, Aleksandra Opinc, Gian Domenico Sebastiani, Roberto Giacomelli, Emanuela Del Giudice, Alma Nunzia Olivieri, Abdurrahman Tufan, Riza Kan Kardas, Rossana Nuzzolese, Fabio Cardinale, Ewa Więsik–Szewczyk, Parretti Veronica, Maria Tarsia, Florenzo Iannone, Francesca Della Casa, Claudia Fabiani, Bruno Frediani, Alberto Balistreri, Donato Rigante, Luca Cantarini,
Long-term efficacy and safety of tocilizumab (TCZ) in adult-onset Still's disease (AOSD) mostly derive from small case series. Herein we report a registry-based study investigating TCZ efficacy and safety in a cohort of patients with AOSD evaluated by clinical and serum inflammatory markers as well as drug retention rate analysis. This is an international multicentre study analyzing data from patients with AOSD regularly enrolled in the AIDA registry. TCZ efficacy was evaluated between baseline and ...
Tópico(s): Family and Disability Support Research
2022 - Elsevier BV | Seminars in Arthritis and Rheumatism
Produção Nacional
Revisado por pares
Francesca Della Casa, Antonio Vitale, Giuseppe Lopalco, Piero Ruscitti, Francesco Ciccia, Giacomo Emmi, Marco Cattalini, Ewa Więsik–Szewczyk, Maria Cristina Maggio, Benson Ogunjimi, Petros P. Sfikakis, Abdurrahman Tufan, Sulaiman M. Al‐Mayouf, Emanuela Del Giudice, Emma Aragona, Francesco La Torre, Jurgen Sota, Sergio Colella, Ilenia Di Cola, Daniela Iacono, Irene Mattioli, Karina Jahnz‐Różyk, Rik Joos, Katerina Laskari, Carla Gaggiano, Anna Abbruzzese, Paola Cipriani, Gelsomina Rozza, Alhanouf AlSaleem, Derya Yıldırım, Maria Tarsia, Gaafar Ragab, Francesca Ricci, Fabio Cardinale, Marcelina Korzeniowska, Micol Frassi, Valeria Caggiano, Moustafa Ali Saad, Rosa Maria Rodrigues Pereira, Virginia Berlengiero, Stefano Gentileschi, Silvana Guerriero, Teresa Giani, Viviana Gelardi, Florenzo Iannone, Henrique Ayres Mayrink Giardini, Ibrahim Almaghlouth, R. C. Kardaş, Djouher Ait‐Idir, Bruno Frediani, Alberto Balistreri, Claudia Fabiani, Donato Rigante, Luca Cantarini,
Objective This paper points out the design, development and deployment of the AutoInflammatory Disease Alliance (AIDA) International Registry dedicated to pediatric and adult patients affected by Undifferentiated Systemic AutoInflammatory Diseases (USAIDs). Methods This is an electronic registry employed for real-world data collection about demographics, clinical, laboratory, instrumental and socioeconomic data of USAIDs patients. Data recruitment, based on the Research Electronic Data Capture (REDCap) ...
Tópico(s): Osteomyelitis and Bone Disorders Research
2022 - Frontiers Media | Frontiers in Medicine
Produção Nacional
Revisado por pares
Carla Gaggiano, Antonio Vitale, Abdurrahman Tufan, Gaafar Ragab, Emma Aragona, Ewa Więsik–Szewczyk, Djouher Ait‐Idir, Giovanni Conti, Ludovica Iezzi, Maria Cristina Maggio, Marco Cattalini, Francesco La Torre, Giuseppe Lopalco, Elena Verrecchia, Amato de Paulis, Ali Şahin, Antonella Insalaco, Petros P. Sfikakis, Achille Marino, Micol Frassi, Benson Ogunjimi, Daniela Opriș-Belinski, Paola Parronchi, Giacomo Emmi, Farhad Shahram, Francesco Ciccia, Matteo Piga, José Hernández‐Rodríguez, Rosa Maria Rodrigues Pereira, Maria Alessio, Roberta Naddei, Alma Nunzia Olivieri, Emanuela Del Giudice, Paolo Sfriso, Piero Ruscitti, Francesca Li Gobbi, Hamit Küçük, Jurgen Sota, Mohamed Hussein, Giuseppe Malizia, Karina Jahnz‐Różyk, R. Sari-Hamidou, Mery Romeo, Francesca Ricci, Fabio Cardinale, Florenzo Iannone, Francesca Della Casa, Marco Francesco Natale, Katerina Laskari, Teresa Giani, Franco Franceschini, Vito Sabato, Derya Yıldırım, Valeria Caggiano, Mohamed Tharwat Hegazy, Rosalba Di Marzo, Aleksandra Kucharczyk, G. Khellaf, Maria Tarsia, Ibrahim Almaghlouth, Ahmed Hatem Laymouna, Violetta Mastrorilli, Laura Dotta, Luca Benacquista, Salvatore Grosso, Francesca Crisafulli, Veronica Parretti, Heitor F. Giordano, Ayman Abdel-Monem Ahmed Mahmoud, Rossana Nuzzolese, Marta De Musso, Cecilia Beatrice Chighizola, Stefano Gentileschi, Mirella Morrone, Ilenia Di Cola, Veronica Spedicato, Henrique Ayres Mayrink Giardini, İ. Vasi, Alessandra Renieri, Alessandra Fabbiani, Maria Antonietta Mencarelli, Bruno Frediani, Alberto Balistreri, Gian Marco Tosi, Claudia Fabiani, Merav Lidar, Donato Rigante, Luca Cantarini,
The present manuscript aims to describe an international, electronic-based, user-friendly and interoperable patient registry for monogenic autoinflammatory diseases (mAIDs), developed in the contest of the Autoinflammatory Diseases Alliance (AIDA) Network.This is an electronic platform, based on the Research Electronic Data Capture (REDCap) tool, used for real-world data collection of demographics, clinical, laboratory, instrumental and socioeconomic data of mAIDs patients. The instrument has flexibility, ...
Tópico(s): Eosinophilic Esophagitis
2022 - Frontiers Media | Frontiers in Medicine
Produção Nacional
Revisado por pares
Francesca Della Casa, Antonio Vitale, Rosa Maria Rodrigues Pereira, Silvana Guerriero, Gaafar Ragab, Giuseppe Lopalco, Marco Cattalini, Irene Mattioli, Paola Parronchi, Maria Pia Paroli, Emanuela Del Giudice, Carla Gaggiano, Marilia Ambiel Dagostin, Valeria Albano, Mahmoud Soliman, Sergio Colella, Giuseppe Nascimbeni, Jurgen Sota, Isabele P. B. Antonelli, Giovanni Alessio, Valeria Caggiano, Abdurrahman Tufan, Rana Hussein Amin, Maria Tarsia, Mahmoud Ghanema, Florenzo Iannone, Francesca Ricci, Francesco La Torre, Ewa Więsik–Szewczyk, Edoardo Conticini, Stefano Gentileschi, Rosanna Dammacco, Rolando Cimaz, Bruno Frediani, Anna Abbruzzese, Piero Ruscitti, Gian Marco Tosi, Heitor F. Giordano, Alessandro Conforti, Alberto Balistreri, Donato Rigante, Luca Cantarini, Claudia Fabiani,
This article points out the design, methods, development and deployment of the international registry promoted by the AutoInflammatory Disease Alliance (AIDA) Network with the aim to define and assess paediatric and adult patients with immune-mediated scleritis. This registry collects both retrospective and prospective real-world data from patients with non-infectious scleritis through the Research Electronic Data Capture (REDCap) tool and aims to promote knowledge and real-life evidence from patients ...
Tópico(s): Inflammasome and immune disorders
2022 - Adis, Springer Healthcare | Ophthalmology and Therapy
Marco Guarneri, Letizia Scola, Rosa Maria Giarratana, M Bova, Caterina Carollo, Giuseppe Lo Re, Leonardo Calandra, Domenico Lio, Carmela Rita Balistreri, Santina Cottone,
Chronic kidney disease (CKD) is characterized by an increased risk of kidney failure and end-stage renal disease (ESRD). Aging and comorbidities as cardiovascular diseases, metabolic disorders, infectious diseases, or tumors, might increase the risk of dialysis. In addition, genetic susceptibility factors might modulate kidney damage evolution. We have analyzed, in a group of ESRD patients and matched controls, a set of SNPs of genes (
Tópico(s): Macrophage Migration Inhibitory Factor
2022 - Multidisciplinary Digital Publishing Institute | Genes
W. Allan Walker, François Desjeux,
... Ascher AP Aschoff Merja Ashorn Frederic Auber William Balistreri Ronald Ball Arrigo Barabino Odile Barsotti K Bauer Dominique Belli C Ben Hamida Pierre-Henri Benhamou Olivier Bernard ZA Bhutta Jacques Bindels Edouard Bingen Ingvar Bjarnason Christine Bodemer Michel Boisset Durval Rosa Borges Flavia Bortolotti Athos Bousvaros Marie-Christine Boutron ...
2000 - Lippincott Williams & Wilkins | Journal of Pediatric Gastroenterology and Nutrition
Letizia Scola, Rosa Maria Giarratana, Calogera Pisano, Giovanni Ruvolo, Vincenzo Marinello, Domenico Lio, Carmela Rita Balistreri,
Tópico(s): Aortic Disease and Treatment Approaches
2020 - Elsevier BV | Meta Gene
Produção Nacional
Revisado por pares
Francesca Della Casa, Antonio Vitale, Marco Cattalini, Francesco La Torre, Giovanna Capozio, Emanuela Del Giudice, Maria Cristina Maggio, Giovanni Conti, Maria Alessio, Benson Ogunjimi, Gaafar Ragab, Giacomo Emmi, Emma Aragona, Teresa Giani, Giuseppe Lopalco, Paola Parronchi, Farhad Shahram, Elena Verrecchia, Francesca Ricci, Fabio Cardinale, Silvia Di Noi, Rossana Nuzzolese, Riccardo Lubrano, Serena Patroniti, Roberta Naddei, Vito Sabato, Mohamed Hussein, Laura Dotta, Violetta Mastrorilli, Stefano Gentileschi, Abdurrahman Tufan, Valeria Caggiano, Mohamed Tharwat Hegazy, Jurgen Sota, Ibrahim Almaghlouth, Amr Awad Ibrahim, Ewa Więsik–Szewczyk, Burcugul Ozkiziltas, Salvatore Grosso, Micol Frassi, Maria Tarsia, Rosa Maria Rodrigues Pereira, Maged Taymour, Carla Gaggiano, Sergio Colella, Claudia Fabiani, Maria Morrone, Piero Ruscitti, Bruno Frediani, Veronica Spedicato, Henrique Ayres Mayrink Giardini, Alberto Balistreri, Donato Rigante, Luca Cantarini,
Objective Aim of this paper is to illustrate the methodology, design, and development of the AutoInflammatory Disease Alliance (AIDA) International Registry dedicated to patients with the Periodic Fever, Aphthous stomatitis, Pharyngitis, and cervical Adenitis (PFAPA) syndrome. Methods This is a physician-driven, non-population- and electronic-based registry proposed to gather real-world demographics, clinical, laboratory, instrumental and socioeconomic data from PFAPA patients. Data recruitment is ...
Tópico(s): Hematological disorders and diagnostics
2022 - Frontiers Media | Frontiers in Pediatrics
Produção Nacional
Revisado por pares
Antonio Vitale, Valeria Caggiano, Maria Cristina Maggio, Giuseppe Lopalco, Giacomo Emmi, Jurgen Sota, Francesco La Torre, Piero Ruscitti, Elena Bartoloni, Giovanni Conti, Claudia Fabiani, Irene Mattioli, Carla Gaggiano, Fabio Cardinale, Lorenzo Dagna, Corrado Campochiaro, Roberto Giacomelli, Alberto Balistreri, Katerina Laskari, Abdurrahman Tufan, Gaafar Ragab, Ibrahim Almaghlouth, Ewa Więsik–Szewczyk, Rosa Maria Rodrigues Pereira, Bruno Frediani, Florenzo Iannone, Petros P. Sfikakis, Luca Cantarini,
Background Treatment with biotechnological anti-interleukin (IL)-1 agents is recommended in patients with Still's disease especially in cases refractory to glucocorticoids and conventional disease modifying anti-rheumatic drugs (cDMARDs), avoiding a long-term glucocorticoids exposure. In cases with refractory arthritis, IL-6 inhibitors have shown to be effective on articular inflammatory involvement. Objectives The objective of the present study is to evaluate any difference in the effectiveness of the IL-1β ...
Tópico(s): Lymphoma Diagnosis and Treatment
2023 - BMJ | Annals of the Rheumatic Diseases
Produção Nacional
Revisado por pares
Jurgen Sota, Antonio Vitale, Ewa Więsik–Szewczyk, Micol Frassi, Giuseppe Lopalco, Giacomo Emmi, Marcello Govoni, Amato de Paulis, Achille Marino, Antonio Gidaro, Sara Monti, Daniela Opriș-Belinski, Rosa Maria Rodrigues Pereira, Karina Jahnz‐Różyk, Carla Gaggiano, Francesca Crisafulli, Florenzo Iannone, Irene Mattioli, Francesca Ruffilli, Ilaria Mormile, Katarzyna Rybak, Valeria Caggiano, Paolo Airò, Abdurrahman Tufan, Stefano Gentileschi, Gaafar Ragab, Ibrahim Almaghlouth, Adham Aboul-Fotouh Khalil, Marco Cattalini, Francesco La Torre, Maria Tarsia, Henrique Ayres Mayrink Giardini, Moustafa Ali Saad, Monica Bocchia, Federico Caroni, Teresa Giani, Élisa Cinotti, Piero Ruscitti, Pietro Rubegni, Marilia Ambiel Dagostin, Bruno Frediani, Aslıhan Avanoğlu Güler, Francesca Della Casa, Maria Cristina Maggio, Andreas Recke, Dagmar von Bubnoff, Karoline Krause, Alberto Balistreri, Claudia Fabiani, Donato Rigante, Luca Cantarini,
The present paper describes the design, development, and implementation of the AutoInflammatory Disease Alliance (AIDA) International Registry specifically dedicated to patients with Schnitzler's syndrome.This is a clinical physician-driven, population- and electronic-based registry implemented for the retrospective and prospective collection of real-life data from patients with Schnitzler's syndrome; the registry is based on the Research Electronic Data Capture (REDCap) tool, which is designed to ...
Tópico(s): interferon and immune responses
2022 - Frontiers Media | Frontiers in Medicine
Mirko Di Rosa, Jacopo Sabbatinelli, Angelica Giuliani, Miriam Carella, Daniele Magro, Leonardo Biscetti, Luca Soraci, Francesco Spannella, Massimiliano Fedecostante, Federica Lenci, Elena Tortato, Lorenzo Pimpini, Maurizio Burattini, S Cecchini, Antonio Cherubini, Anna Rita Bonfigli, Maria Capalbo, Antonio Procopio, Carmela Rita Balistreri, Fabiola Olivieri,
Tópico(s): Peripheral Artery Disease Management
2024 - BioMed Central | Immunity & Ageing
Mirko Di Rosa, Jacopo Sabbatinelli, Angelica Giuliani, Miriam Carella, Daniele Magro, Leonardo Biscetti, Luca Soraci, Francesco Spannella, Massimiliano Fedecostante, Federica Lenci, Elena Tortato, Lorenzo Pimpini, Maurizio Burattini, S Cecchini, Antonio Cherubini, Anna Rita Bonfigli, Maria Capalbo, Antonio Procopio, Carmela Rita Balistreri, Fabiola Olivieri,
Systemic inflammation significantly increases the risk of short- and long-term mortality in geriatric hospitalized patients. To predict mortality in older patients with various age-related diseases and infections, including COVID-19, inflammatory biomarkers such as the C-reactive protein (CRP) to albumin ratio (CAR), and related scores and indexes, i.e. Glasgow Prognostic Score (GPS), modified GPS (mGPS), and high sensitivity (hs)-mGPS, have been increasingly utilized. Despite their easy affordability ...
Tópico(s): Nutrition and Health in Aging
2024 - BioMed Central | Immunity & Ageing