Joana Guimarães, Eduarda Matos, Maria José Rosas, Maria Augusta Vieira‐Coelho, Nuno Borges, Flora Correia, Ruí Vaz, Carolina Garrett,
Tópico(s): Transcranial Magnetic Stimulation Studies
2009 - Springer Science+Business Media | Journal of Neurology
João B. Costa, Ji Hoon Park, Adam Jorgensen, Joana Silva‐Correia, Rui L. Reis, Joaquím M. Oliveira, Anthony Atala, James J. Yoo, Sang Jin Lee,
Advanced strategies to bioengineer a fibrocartilaginous tissue to restore the function of the meniscus are necessary. Currently, 3D bioprinting technologies have been employed to fabricate clinically relevant patient-specific complex constructs to address unmet clinical needs. In this study, a highly elastic hybrid construct for fibrocartilaginous regeneration is produced by coprinting a cell-laden gellan gum/fibrinogen (GG/FB) composite bioink together with a silk fibroin methacrylate (Sil-MA) bioink ...
Tópico(s): Bone Tissue Engineering Materials
2020 - American Chemical Society | Chemistry of Materials
Produção Nacional
Revisado por pares
Tiago Ribeiro, Abel Correia, Rui Biscaia,
Purpose Despite the recognition that citizens' perceptions of mega sport events' social impact is critical for the sustainable development of these events and host cities, most previous studies have not taken into consideration how these perceptions may change over time. This study examines citizens' social impact perceptions of the 2016 Rio Olympic Games before and after the event. Design/methodology/approach Data were collected amongst local residents of Rio de Janeiro pre- and post-event ( n = 256). ...
Tópico(s): Recreation, Leisure, Wilderness Management
2020 - Emerald Publishing Limited | Sport Business and Management An International Journal
Produção Nacional
Revisado por pares
Rita C. Guedes, Kaline Coutinho, Benedito J. Costa Cabral, Sylvio Canuto, Catarina F. Correia, Rui M. Borges dos Santos, José A. Martinho Simões,
Monte Carlo statistical mechanics simulations, density-functional theory calculations, time-resolved photoacoustic calorimetry, and isoperibol reaction-solution calorimetry experiments were carried out to investigate the solvation enthalpies and solvent effects on the energetics of the phenol O−H bond in benzene and acetonitrile. A good agreement between theoretical and experimental results is obtained for the solvation enthalpies of phenol in benzene and acetonitrile. The theoretical calculations ...
Tópico(s): Atmospheric chemistry and aerosols
2003 - American Chemical Society | The Journal of Physical Chemistry A
Hugo Sousa, Ana L Pinto-Correia, Rui Medeiros, Mário Dinis‐Ribeiro,
AIM:To examine the possible role of the Epstein-Barr Virus (EBV) in the development of gastric adenocarcinoma (GC).It is unclear whether EBV is involved in GC development or is a consequence of gastric inflammation secondary to immunosuppressive treatments.METHODS: A systematic review was carried out of all published observational studies on the temporal association between EBV and GC, with a view to determine a causal relationship.RESULTS: The present study showed that the w o r l d w i d e c r u ...
Tópico(s): Cholangiocarcinoma and Gallbladder Cancer Studies
2008 - Baishideng Publishing Group | World Journal of Gastroenterology
Leonor Galhardo, João P.S. Correia, Rui F. Oliveira,
Abstract Male African cichlids ( Oreochromis mossambicus ) establish territories on the substrate upon which spawning pits are dug, thus attracting females. The substrate, therefore, plays a very significant role in its lifecycle. The effects of substrate access on behaviour and physiology in captivity were assessed. Mixed-sex, all-male and all-female groups were observed for five days, with and without substrate. Social patterns, behaviour directed towards the substrate, locomotor activity and spatial ...
Tópico(s): Amphibian and Reptile Biology
2008 - Cambridge University Press | Animal Welfare
Tânia Correia, Rui Cunha Marques,
This research applies the stochastic frontier analysis benchmarking method to measure the performance of the water sector in Portugal. It estimates a multiproduct translog cost function in order to study the efficiency of the water and sewerage services, using an unbalanced panel comprising 68 Portuguese water utilities for the biennium 2004–2005. The sample is formed by concessionaire companies, municipal companies and semi-autonomous utilities which represent approximately 61% of the Portuguese ...
Tópico(s): Public-Private Partnership Projects
2010 - UWA Publishing | Water Policy
Produção Nacional
Revisado por pares
Emília Moreira, Manuel Correia, Rui Magalhães, Carolina Silva,
<i>Background:</i> Several studies conducted in hospital emergency departments have shown that most patients delay in responding to stroke symptoms. In the general population, recognition of stroke and the appropriate reactions are important for prevention and acute treatment, particularly in areas with a high stroke incidence. The objective of this study was to compare general knowledge about stroke/TIA and prompt action in urban and rural populations. <i>Meth</i><i>ods:</ ...
Tópico(s): Traumatic Brain Injury and Neurovascular Disturbances
2011 - Karger Publishers | Neuroepidemiology
Madalena Dionı́sio, Anabela C. Fernandes, João F. Mano, Natália T. Correia, Rui C. Sousa,
To study the influence of PEO on the relaxation process of PMMA, the real and imaginary parts of the permittivity, ε' and ε' ', of PEO/PMMA blends (with PEO contents up to 25 wt %) were measured as a function of frequency and temperature, and the results obtained were compared with those of pure PMMA. It is shown that the presence of PEO broadens the relaxation process of PMMA and increases its relaxation strength. The lower Tg component (PEO) has a plasticizing effect on the relaxation of PMMA, for the ...
Tópico(s): Material Properties and Processing
2000 - American Chemical Society | Macromolecules
Filipe Nascimento, Paula A. Pousinha, Alexandra Marçal Correia, Rui Gomes, Ana M. Sebastião, Joaquim A. Ribeiro,
Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease leading to motor neuron dysfunction resulting in impairment of neuromuscular transmission. A2A adenosine receptors have already been considered as a potential therapeutical target for ALS but their neuromodulatory role at the neuromuscular junction in ALS remains to be clarified. In the present work, we evaluated the effects of A2A receptors on neuromuscular transmission of an animal model of ALS: SOD1(G93A) mice either in the pre- ...
Tópico(s): Adenosine and Purinergic Signaling
2014 - Public Library of Science | PLoS ONE
Nuno M. Oliveira, Clara R. Correia, Rui L. Reis, João F. Mano,
Stable liquid marbles (LM) are produced by coating liquid droplets with a hydrophobic powder. The used hydrophobic powder is produced by fluorosilanization of diatomaceous earth, used before to produce superhydrophobic structures. Here, the use of LM is proposed for high‐throughput drug screening on anchorage‐dependent cells. To provide the required cell adhesion sites inside the liquid environment of LM, surface‐modified poly( l ‐lactic acid) microparticles are used. A simple method that takes advantage ...
Tópico(s): Micro and Nano Robotics
2014 - Wiley | Advanced Healthcare Materials
Clara R. Correia, Rui L. Reis, João F. Mano,
Liquified capsules featuring (i) an external shell by layer-by-layer assembly of poly(l-lysine), alginate, and chitosan, and encapsulating (ii) surface functionalized poly(l-lactic acid) (PLLA) microparticles were developed. We hypothesize that, while the liquified environment enhances the diffusion of essential molecules for cell survival, microparticles dispersed in the liquified core of capsules provide the physical support required for cellular functions of anchorage-dependent cells. The influence ...
Tópico(s): Electrospun Nanofibers in Biomedical Applications
2013 - American Chemical Society | Biomacromolecules
Alexandre Gonçalves, Gilberto Igrejas, Hajer Radhouani, Susana Correia, Rui Pacheco, Tiago Santos, Ricardo Monteiro, Ana Guerra, Francisco Petrucci‐Fonseca, Francisco Brito, Cármen Torres, Patrícia Poeta,
The aim of this study was to report the antimicrobial resistance, the molecular mechanisms associated and the detection of virulence determinants within faecal Enterococcus spp. and Escherichia coli isolates of Iberian wolf. Enterococci (n = 227) and E. coli (n = 195) isolates were obtained from faecal samples of Iberian wolf (Canis lupus signatus). High rates of resistance were detected for tetracycline and erythromycin among the enterococci isolates, and most of resistant isolates harboured the tet(M) ...
Tópico(s): Salmonella and Campylobacter epidemiology
2013 - Oxford University Press | Letters in Applied Microbiology
Sara Lima, João Correia, Rui Ribeiro, Rui Moura Martins, Nuno Alegrete, Jorge Coutinho, Gilberto Melo Costa,
Elbow dislocations in children are rare. 16 Stans A. Heirich S. Dislocations of the elbow. in: Beaty J. Kasser J. Rockwood & Wilkinś fractures in children. 7th ed. Lippincott Williams & Wilkins, Philadelphia, PA2010 Google Scholar , 14 Rasool M.N. Dislocation of the elbow in children. J Bone Joint Surg (Br). 2004; 86-B: 1050-1058https://doi.org/10.1302/0301-620X.86B7 Crossref Google Scholar They may be associated with other fractures of this region, with the most common being medial epicondyle avulsion. ...
Tópico(s): Orthopedic Surgery and Rehabilitation
2013 - Elsevier BV | Journal of Shoulder and Elbow Surgery
Manuel Correia, Rui Magalhães, Mário Rui Silva, Ilda Matos, Carolina Silva,
<b><i>Background/Aim:</i></b> Differences in stroke incidence and mortality between regions could stem from differences in the incidence of particular stroke types and long-term prognosis. The aim of this study was to investigate whether different risk profiles and stroke types underlie the difference in stroke incidence and patient long-term survival in rural and urban populations. <b><i>Methods:</i></b> All suspected first-ever-in-a-lifetime strokes ...
Tópico(s): Cerebral Venous Sinus Thrombosis
2013 - Karger Publishers | Cerebrovascular Diseases Extra
Francisco Duarte, Filipe Casimiro, Diogo Correia, Rui Mendes, Adelino Ferreira,
This paper describes a new pavement energy harvest system developed in Portugal by the Waydip Company with the collaboration of the pavement mechanics laboratory of the University of Coimbra. The electric energy generated by the Waynergy system for people during 1 h was 525 J or 0·15 W·h. It is expected that the Waynergy system for vehicles could generate substantial electrical energy, which can be used not only to charge batteries for electric vehicles, but also for general consumption through ...
Tópico(s): Gas Sensing Nanomaterials and Sensors
2013 - | Proceedings of the Institution of Civil Engineers - Municipal Engineer
Produção Nacional
Revisado por pares
Paolo F. Fabene, Luciana Correia, Rui A. Carvalho, Ésper A. Cavalheiro, Marina Bentivoglio,
At variance with pilocarpine-induced epilepsy in the laboratory rat, pilocarpine administration to the tropical rodent Proechimys guyannensis (casiragua) elicited an acute seizure that did not develop in long-lasting status epilepticus and was not followed by spontaneous seizures up to 30 days, when the hippocampus was investigated in treated and control animals. Nissl staining revealed in Proechimys a highly developed hippocampus, with thick hippocampal commissures and continuity of the rostral ...
Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms
2001 - Elsevier BV | Neuroscience
Inês Palmela, Leonor Correia, Rui F. M. Silva, Hiroyuki Sasaki, Kwang S. Kim, Dora Brites, María Alexandra Brito,
Ursodeoxycholic acid and its main conjugate glycoursodeoxycholic acid are bile acids with neuroprotective properties. Our previous studies demonstrated their anti-apoptotic, anti-inflammatory, and antioxidant properties in neural cells exposed to elevated levels of unconjugated bilirubin (UCB) as in severe jaundice. In a simplified model of the blood-brain barrier, formed by confluent monolayers of a cell line of human brain microvascular endothelial cells, UCB has shown to induce caspase-3 activation ...
Tópico(s): Heme Oxygenase-1 and Carbon Monoxide
2015 - Frontiers Media | Frontiers in Neuroscience
Tânia Vieira, Ana Alves, Jorge de Brito, João R. Correia, Rui V. Silva,
Information on the effects of incorporating fine recycled ceramic aggregates on concrete's durability is very scarce. This paper presents an experimental study using aggregates sourced from crushed red clay ceramic bricks (CBAs) and sanitary ware (SWA). Different concrete mixes were produced where the fine natural aggregate fraction was partially or fully replaced (20%, 50% and 100%, by volume) by each of these materials. Shrinkage, water absorption by immersion, water absorption by capillary action, ...
Tópico(s): Innovative concrete reinforcement materials
2015 - Elsevier BV | Materials & Design
Clara R. Correia, Rui L. Reis, João F. Mano,
Cartilage tissue is a complex nonlinear, viscoelastic, anisotropic, and multiphasic material with a very low coefficient of friction, which allows to withstand millions of cycles of joint loading over decades of wear. Upon damage, cartilage tissue has a low self-reparative capacity due to the lack of neural connections, vascularization, and a latent pool of stem/chondro-progenitor cells. Therefore, the healing of articular cartilage defects remains a significant clinical challenge, affecting millions ...
Tópico(s): Silk-based biomaterials and applications
2015 - Springer Nature | Advances in experimental medicine and biology
Narcisa M. Bandarra, Paula A. Lopes, Susana V. Martins, Júlia Ferreira, Cristina M. Alfaia, Eva A. Rolo, Jorge Correia, Rui Pinto, Rebeca P. Ramos‐Bueno, Irineu Batista, José A. M. Prates, José Luis Guil‐Guerrero,
In this study, we hypothesized that the incorporation of docosahexaenoic acid (DHA) in tissues will be higher when it is ingested as triacylglycerols (TAG) structured at the sn-2 position, which enhances efficacy and health benefits of dietary DHA n-3 supplementation. Ten-week-old Golden Syrian male hamsters were randomly allocated into 4 dietary groups with 10 animals in each: linseed oil (LSO; control group), fish oil (FO), fish oil ethyl esters (FO-EE), and structured DHA at the sn-2 position of TAG ( ...
Tópico(s): Diet and metabolism studies
2016 - Elsevier BV | Nutrition Research
Manuel Correia, Rui Magalhães, Rui Felgueiras, Cláudia Quintas, Laura Guimarães, Carolina Silva,
Objective Year 2000 marked a turning point in stroke prevention and treatment in Portugal. In face of high incidence rates stroke awareness campaigns, close surveillance of vascular risk factors and implementation of hospital stroke units were advanced by the National Health Authorities. To understand the effect of such measures, we assessed changes in stroke incidence and short-term outcome using data from two community-based registers undertaken in Porto in 1998–2000 and 2009–2011. Methods We ...
Tópico(s): Stroke Rehabilitation and Recovery
2016 - SAGE Publishing | International Journal of Stroke
Hoang Phan, Christopher Leigh Blizzard, Mathew J. Reeves, Amanda G. Thrift, Dominique A. Cadilhac, Jonathan Sturm, Emma Heeley, Petr Otáhal, Vemmos Konstantinos, Craig S. Anderson, Priya Parmar, Rita Krishnamurthi, Suzanne Barker‐Collo, Valery L. Feigin, Yannick Béjot, Norberto L. Cabral, Antonio Carolei, Simona Sacco, Nicolas Chausson, Stéphane Olindo, Peter M. Rothwell, Carolina Silva, Manuel Correia, Rui Magalhães, Peter Appelros, Janika Kõrv, Riina Vibo, César Minelli, Seana Gall,
Women are reported to have greater mortality after stroke than men, but the reasons are uncertain. We examined sex differences in mortality at 1 and 5 years after stroke and identified factors contributing to these differences.Individual participant data for incident strokes were obtained from 13 population-based incidence studies conducted in Europe, Australasia, South America, and the Caribbean between 1987 and 2013. Data on sociodemographics, stroke-related factors, prestroke health, and 1- and ...
Tópico(s): Cerebrovascular and Carotid Artery Diseases
2017 - Lippincott Williams & Wilkins | Circulation Cardiovascular Quality and Outcomes
Rita López‐Cebral, Joana Silva‐Correia, Rui L. Reis, Thiago H. Silva, Joaquím M. Oliveira,
Damage to peripheral nerves is a widely extended health problem, causing important socioeconomic costs worldwide. Indeed, peripheral nerve injuries (PNI) have been concerning the medical community for many decades. Nevertheless, despite the increase in knowledge in the injury physiopathology and the great research efforts being undertaken, the current standard grafting strategies used to repair PNI are not as efficient as desired. Although alternative engineered nerve grafts are already commercialized, ...
Tópico(s): Tissue Engineering and Regenerative Medicine
2017 - American Chemical Society | ACS Biomaterials Science & Engineering
Cristiana R. Silva, Pedro S. Babo, Maurizio Gulino, Lígia Costa, Joaquím M. Oliveira, Joana Silva‐Correia, Rui M. A. Domingues, Rui L. Reis, Manuela E. Gomes,
Bioengineered soft tissues on any meaningful scale or complexity must incorporate aspects of the functional tissue, namely a vasculature, providing cells oxygen and nutrients critical for their survival. However, the ability of tissue engineering strategies to promote a fast revascularization is critically limited. Particularly in endodontic regenerative therapies, the complicated anatomy of the root canal system, and the narrow apical access limit the supply of new blood vessels and pulp tissue ...
Tópico(s): Endodontics and Root Canal Treatments
2018 - Elsevier BV | Acta Biomaterialia
Clara R. Correia, Rui L. Reis, João F. Mano,
Abstract Cell encapsulation systems are being increasingly applied as multifunctional strategies to regenerate tissues. Lessons afforded with encapsulation systems aiming to treat endocrine diseases seem to be highly valuable for the tissue engineering and regenerative medicine (TERM) systems of today, in which tissue regeneration and biomaterial integration are key components. Innumerous multifunctional systems for cell compartmentalization are being proposed to meet the specific needs required ...
Tópico(s): Electrohydrodynamics and Fluid Dynamics
2018 - Wiley | Advanced Healthcare Materials
Catarina Oliveira Miranda, Adriana Marcelo, Teresa P. Silva, João Barata, Ana Vasconcelos‐Ferreira, Dina Pereira, Clévio Nóbrega, Sónia Duarte, Inês Barros, Joana Alves, José Sereno, Lorena Petrella, João Castelhano, Vítor H. Paiva, Paulo Rodrigues‐Santos, Vera Alves, Isabel Nunes‐Correia, Rui Jorge Nobre, Célia Gomes, Miguel Castelo‐Branco, Luís Pereira de Almeida,
Machado-Joseph disease (MJD) or spinocerebellar ataxia type 3, the most common dominant spinocerebellar ataxia (SCA) worldwide, is caused by over-repetition of a CAG repeat in the ATXN3/MJD1 gene, which translates into a polyglutamine tract within the ataxin-3 protein. There is no treatment for this fatal disorder. Despite evidence of the safety and efficacy of mesenchymal stromal cells (MSCs) in delaying SCA disease progression in exploratory clinical trials, unanticipated regression of patients to ...
Tópico(s): Mesenchymal stem cell research
2018 - Elsevier BV | Molecular Therapy
Produção Nacional
Revisado por pares
Thiago Santos, Abel Correia, Rui Biscaia, Ann Pegoraro,
Purpose The purpose of this paper is to conceptualise and measure the construct of fan engagement through social networking sites (SNS). Design/methodology/approach A multi-stage procedure was completed to validate the proposed fan engagement through SNS model with three first-order constructs (fan-to-fan relationships, team-to-fan relationships and fan co-creation). First, a preliminary analysis of the proposed items to capture fan engagement through SNS was conducted through expert review. Second, ...
Tópico(s): Technology Adoption and User Behaviour
2018 - Emerald Publishing Limited | International Journal of Sports Marketing and Sponsorship
Eduarda P. Oliveira, Joana Silva‐Correia, Rui L. Reis, Joaquím M. Oliveira,
The Central Nervous System (CNS) is a highly complex organ that works as the control centre of the body, managing vital and non-vital functions. Neuro-diseases can lead to the degeneration of neural tissue, breakage of the neuronal networks which can affect vital functions and originate cognitive deficits. The complexity of the neural networks, their components and the low regenerative capacity of the CNS are on the basis for the lack of recovery, having the need for therapies that can promote tissue ...
Tópico(s): Neuroscience and Neural Engineering
2018 - Springer Nature | Advances in experimental medicine and biology
Romain Sousa, João Pacheco de Almeida, António A. Correia, Rui Pinho,
Distributed plasticity Euler-Bernoulli fiber beams are regularly used by researchers and practitioners to simulate the nonlinear seismic response of reinforced concrete framed structures. This study presents a sensitivity analysis, combining newly proposed and existing goodness-of-fit measures, to identify commonly used engineering modeling options that most critically influence the response accuracy. The dynamic behavior of three distinct structures tested in international blind prediction challenges ...
Tópico(s): Structural Health Monitoring Techniques
2018 - Taylor & Francis | Journal of Earthquake Engineering