... Crossref reports the following articles citing this article:Rui Faria, Pragya Chaube, Hernán E. Morales, Tomas Larsson, Alan ...
Tópico(s): Plant Taxonomy and Phylogenetics
1938 - University of Chicago Press | The Quarterly Review of Biology
Ana Guimarães, Albino Martins, Elisabete D. Pinho, Susana Faria, Rui L. Reis, Nuno M. Neves,
Utilize the dual composition strategy to increase the pore size and solve the low cell infiltration capacity on random nanofiber meshes, an intrinsic limitation of electrospun scaffolds for tissue engineering applications.Polycaprolactone and poly(ethylene oxide) solutions were electrospun simultaneously to obtain a dual composition nanofiber mesh. Selective dissolution of the poly(ethylene oxide) nanofiber fraction was performed. The biologic performance of these enhanced pore size nanofibrous ...
Tópico(s): Tissue Engineering and Regenerative Medicine
2010 - Future Medicine | Nanomedicine
Marta Alves da Silva, Albino Martins, Ana Rita Costa-Pinto, Vítor M. Correlo, P. Sol, Mrinal Bhattacharya, Susana Faria, Rui L. Reis, Nuno M. Neves,
Native articular cartilage is subjected to synovial fluid flow during normal joint function. Thus, it is believed that the morphogenesis of articular cartilage may be positively regulated by the application of similar stimulation in vitro. In the present study, the effect of fluid flow over the chondrogenic differentiation of human bone marrow-derived mesenchymal stem cells (hBM-MSCs) was investigated. We intended to find out whether the shear stress caused by perfusion of the medium through the ...
Tópico(s): Mesenchymal stem cell research
2010 - Wiley | Journal of Tissue Engineering and Regenerative Medicine
Marta Alves da Silva, Ana Rita Costa-Pinto, Albino Martins, Vítor M. Correlo, P. Sol, Mrinal Bhattacharya, Susana Faria, Rui L. Reis, Nuno M. Neves,
Paracrine signalling from chondrocytes has been reported to increase the synthesis and expression of cartilage extracellular matrix (ECM) by stem cells. The use of conditioned medium obtained from chondrocytes for stimulating stem cells chondrogenic differentiation may be a very interesting alternative for moving into the clinical application of these cells, as chondrocytes could be partially replaced by stem cells for this type of application. In the present study we aimed to achieve chondrogenic ...
Tópico(s): Mesenchymal stem cell research
2013 - Wiley | Journal of Tissue Engineering and Regenerative Medicine
Filipe V. S. Lopes, Sandra M. Miranda, Ricardo A.R. Monteiro, Susana Martins, Adrián M.T. Silva, Joaquim L. Faria, Rui A.R. Boaventura, Vítor J.P. Vilar,
Perchloroethylene (PCE) has been detected as one of the major pollutants in indoor air of wastewater treatment plants (WWTPs) with closed facilities. Its hazardousness requires the complete PCE removal from air. For this reason, gas-phase photooxidation of PCE was studied in a continuous-flow tubular photoreactor under simulated solar radiation. Since negligible degradation of PCE was observed by photolysis, photocatalytic oxidation (PCO) experiments were carried out employing a catalytic bed of cellulose ...
Tópico(s): Advanced oxidation water treatment
2013 - Elsevier BV | Applied Catalysis B Environment and Energy
Delirium occurs in up to 80% of patients admitted to intensive care units. Although under-diagnosed, delirium is associated with a significant increase in morbidity and mortality in critical patients. Here, we review the main risk factors, clinical manifestations and preventative and therapeutic approaches (pharmacological and non-pharmacological) for this illness.
Tópico(s): Anesthesia and Sedative Agents
2013 - Associação de Medicina Intensiva Brasileira | Revista Brasileira de Terapia Intensiva
Duarte Toubarro, Mónica Martinez Avila, Youjin Hao, N. Balasubramanian, Yingjun Jing, Rafaél Montiel, Tiago Q. Faria, Rui M. M. Brito, Nélson Simões,
Steinernema carpocapsae is an entomopathogenic nematode widely used for the control of insect pests due to its virulence, which is mainly attributed to the ability the parasitic stage has to overcome insect defences. To identify the mechanisms underlying such a characteristic, we studied a novel serpin-like inhibitor (sc-srp-6) that was detected in a transcriptome analysis. Recombinant Sc-SRP-6 produced in Escherichia coli had a native fold of serpins belonging to the α-1-peptidase family and exhibited ...
Tópico(s): Insect Pest Control Strategies
2013 - Public Library of Science | PLoS ONE
Analuce Canha-Gouveia, Ana Rita Costa-Pinto, Albino Martins, Nuno A. Silva, Susana Faria, Rui A. Sousa, António J. Salgado, Nuno Sousa, Rui L. Reis, Nuno M. Neves,
Hierarchical structures, constituted by polymeric nano and microfibers, have been considered promising scaffolds for tissue engineering strategies, mainly because they mimic, in some way, the complexity and nanoscale detail observed in real organs. The chondrogenic potential of these scaffolds has been previously demonstrated, but their osteogenic potential is not yet corroborated. In order to assess if a hierarchical structure, with nanoscale details incorporated, is an improved scaffold for bone ...
Tópico(s): Electrospun Nanofibers in Biomedical Applications
2015 - IOP Publishing | Biofabrication
Produção Nacional
Revisado por pares
Caio Rodrigues-Silva, Sandra M. Miranda, Filipe V. S. Lopes, Mário J. Silva, Márcia Dezotti, Adrián M.T. Silva, Joaquim L. Faria, Rui A.R. Boaventura, Vítor J.P. Vilar, Eugénia Pinto,
Tópico(s): Indoor Air Quality and Microbial Exposure
2016 - Springer Science+Business Media | Environmental Science and Pollution Research
Solange Magalhães, Luís Alves, Marco Sebastião, Bruno Medronho, Zaida L. Almeida, Tiago Q. Faria, Rui M. M. Brito, Maria João Moreno, Filipe E. Antunes,
The use of enzymes in laundry and dish detergent products is growing. Such tendency implies dedicated studies to understand surfactant‐enzyme interactions. The interactions between surfactants and enzymes and their impact on the catalytic efficiency represent a central problem and were here evaluated using circular dichroism, dynamic light scattering, and enzyme activity determinations. This work focuses on this key issue by evaluating the role of the ethyleneoxide (EO) groups of anionic surfactants ...
Tópico(s): Analytical Chemistry and Chromatography
2016 - American Chemical Society | Biotechnology Progress
Marta Alves da Silva, Albino Martins, Ana Rita Costa-Pinto, Nélson Monteiro, Susana Faria, Rui L. Reis, Nuno M. Neves,
Many efforts are being directed worldwide to the treatment of OA‐focal lesions. The majority of those efforts comprise either the refinement of surgical techniques or combinations of biomaterials with various autologous cells. Herein, we tested electrospun polycaprolactone (PCL) nanofibrous meshes for cartilage tissue engineering. For that, articular chondrocytes (hACs) isolated from human osteoarthritic joints and Wharton's Jelly Stem Cells (hWJSCs) are cultured on electrospun nanofiber meshes, without ...
Tópico(s): Silk-based biomaterials and applications
2017 - Wiley | Biotechnology Journal
Produção Nacional
Revisado por pares
Juliana F. Piai, Marta Alves da Silva, Albino Martins, Ana B. Faia Torres, Susana Faria, Rui L. Reis, Edvani C. Muniz, Nuno M. Neves,
Aiming at improving the biocompatibility of biomaterial scaffolds, surface modification presents a way to preserve their mechanical properties and to improve the surface bioactivity. In this work, chondroitin sulfate (CS) was immobilized at the surface of electrospun poly(caprolactone) nanofiber meshes (PCL NFMs), previously functionalized by UV/O3 exposure and aminolysis. Contact angle, SEM, optical profilometry, FTIR, X-ray photoelectron spectroscopy techniques confirmed the success of CS-immobilization ...
Tópico(s): Osteoarthritis Treatment and Mechanisms
2017 - Elsevier BV | Applied Surface Science
Produção Nacional
Revisado por pares
Valciney Gomes de Barros, Carmen S.D. Rodrigues, Wilmar Alirio Botello Suárez, Rose Maria Duda, R. A. de Oliveira, Eliana S. Da Silva, Joaquim L. Faria, Rui A.R. Boaventura, Luı́s M. Madeira,
Biodigested coffee processing wastewater (CPW) presents a high organic load and does not meet the limits imposed by legislation (namely in Brazil) for discharge into water bodies. Anaerobic digestion generally cannot provide a satisfactory organic matter reduction in CPW as a significant fraction of recalcitrant compounds still persists in the treated effluent. So, this study aims to find alternative ways to remove refractory organic compounds from this wastewater in order to improve the biodegradability ...
Tópico(s): Water Treatment and Disinfection
2019 - Elsevier BV | Environmental Pollution
Produção Nacional
Revisado por pares
Juliana Coatrini Soares, Andrey Coatrini Soares, Valquíria Cruz Rodrigues, Matias Eliseo Melendez, Alexandre César Santos, Eliney Ferreira Faria, Rui Manuel Reis, André Lopes Carvalho, Osvaldo N. Oliveira,
Diagnosis of prostate cancer via PCA3 biomarker detection is promising to be much more efficient than with the prostatic specific antigens currently used. In this study, we present the first electrochemical and impedance-based biosensors that are capable of detecting PCA3 down to 0.128 nmol/L. The biosensors were made with a layer of PCA3-complementary single-stranded DNA (ssDNA) probe, immobilized on a layer-by-layer (LbL) film of chitosan (CHT) and carbon nanotubes (MWCNT). They are highly selective ...
Tópico(s): Molecular Biology Techniques and Applications
2019 - American Chemical Society | ACS Applied Materials & Interfaces
Sílvia Monteiro Fonseca, Sónia Cunha, Sara Faria, Rui Campos, Cristina Queirós,
Emergency Medical Technicians (EMTs) are at high risk for traumatic disorders, and these disorders are more likely if they resort to dysfunctional coping. However, few studies have examined how dysfunctional coping can be decreased, specifically by comparing the impact of personal characteristics, such as resilience, and of occupational factors, such as stress. This study examines the contribution of resilience and perceived stress on EMTs' dysfunctional coping.A total of 502 EMTs (66% men), with ...
Tópico(s): Posttraumatic Stress Disorder Research
2021 - Elsevier BV | International Emergency Nursing
Sandra M. Miranda, Filipe V. S. Lopes, Caio Rodrigues-Silva, Susana Martins, Adrián M.T. Silva, Joaquim L. Faria, Rui A.R. Boaventura, Vítor J.P. Vilar,
Tópico(s): Aerogels and thermal insulation
2014 - Springer Science+Business Media | Environmental Science and Pollution Research
Catarina S. H. Jesus, Zaida L. Almeida, Daniela C. Vaz, Tiago Q. Faria, Rui M. M. Brito,
Protein aggregation into insoluble amyloid fibrils is the hallmark of several neurodegenerative diseases, chief among them Alzheimer’s and Parkinson’s. Although caused by different proteins, these pathologies share some basic molecular mechanisms with familial amyloidotic polyneuropathy (FAP), a rare hereditary neuropathy caused by amyloid formation and deposition by transthyretin (TTR) in the peripheral and autonomic nervous systems. Among the amyloidogenic TTR mutations known, V30M-TTR is the most ...
Tópico(s): Endoplasmic Reticulum Stress and Disease
2016 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Cristina de Mello-Sampayo, Ana Rita Vaz, Sara Carolina Henriques, Adelaide Fernandes, Fabiana Paradinha, Pedro R. Florindo, Paulo Faria, Rui Moreira, Dora Brites, Álvaro Lopes,
Tópico(s): Nicotinic Acetylcholine Receptors Study
2020 - Springer Science+Business Media | Neurotoxicity Research
Miguel Azenha, Rui Faria, Denise Ferreira,
Concrete at early-ages experiences thermal deformations due to the heat generation caused by the cement hydration reactions. These deformations may lead to cracking of concrete, for which the use of numerical models in order to foresee and prevent this problem is of crucial importance. However, these numerical models must be appropriately validated by monitoring the young concrete behaviour. The conducted research regards an experimental work carried out with two main goals: (i) to evaluate the performance ...
Tópico(s): Concrete Corrosion and Durability
2009 - Elsevier BV | Cement and Concrete Composites
Miguel Cervera, Rui Faria, J. Oliver, Tomás Prato,
Tópico(s): Innovative concrete reinforcement materials
2002 - Elsevier BV | Computers & Structures
A numerical prediction of temperatures and stresses on a R/C foundation of a steel wind tower, and during the first weeks after casting, is presented in this paper. The thermo-mechanical methodology adopted for this kind of analysis is introduced first, describing the thermal field engendered in concrete by the heat released during cement hydration, the aging laws that reproduce the growth of the mechanical properties during the early stages and the concrete stresses evaluation. Attention is thereafter ...
Tópico(s): Fire effects on concrete materials
2008 - Elsevier BV | Engineering Structures
Tópico(s): Evolution and Genetic Dynamics
2010 - Elsevier BV | Trends in Ecology & Evolution
Miguel Azenha, Filipe Magalhães, Rui Faria, Álvaro Cunha,
The use of ambient vibration tests to characterize the evolution of E-modulus of concrete right after casting is investigated in this paper. A new methodology is proposed, which starts by casting a concrete cylindrical beam inside a hollow acrylic formwork. This beam is then placed horizontally, simply supported at both extremities, and vertical accelerations resulting from ambient vibration are measured at mid-span. Processing these mid-span acceleration time series using power spectral density ...
Tópico(s): Concrete Corrosion and Durability
2010 - Elsevier BV | Cement and Concrete Research
Miguel Azenha, Koichi Maekawa, Tetsuya Ishida, Rui Faria,
Tópico(s): Concrete and Cement Materials Research
2007 - Springer Science+Business Media | Materials and Structures
Miguel Azenha, Koichi Maekawa, Tetsuya Ishida, Rui Faria,
Tópico(s): Concrete Properties and Behavior
2007 - Springer Science+Business Media | Materials and Structures
Miguel Azenha, Carlos Sousa, Rui Faria, Afonso Serra Neves,
Current practices of structural design in reinforced concrete (RC) structures usually account for stresses caused by phenomena such as heat of hydration and drying shrinkage in a quite simplified manner. The present paper aims to evaluate the consequences of explicitly considering self-induced stresses, which actually vary significantly within structural cross-sections, combined with stresses caused by external loads. The used numerical framework involves the explicit calculation of the temperature ...
Tópico(s): Innovative concrete reinforcement materials
2011 - Elsevier BV | Engineering Structures
Urko M. Marigorta, Óscar Lao, Ferrán Casals, Francesc Calafell, Carlos Morcillo-Suárez, Rui Faria, Elena Bosch, François Serra, Jaume Bertranpetit, Hernán Dopazo, Arcadi Navarro,
Abstract Background Searching for associations between genetic variants and complex diseases has been a very active area of research for over two decades. More than 51,000 potential associations have been studied and published, a figure that keeps increasing, especially with the recent explosion of array-based Genome-Wide Association Studies. Even if the number of true associations described so far is high, many of the putative risk variants detected so far have failed to be consistently replicated ...
Tópico(s): Epigenetics and DNA Methylation
2011 - BioMed Central | BMC Genomics
Miguel Azenha, Rui Faria, Filipe Magalhães, Leonel Ramos, Álvaro Cunha,
Tópico(s): Structural Engineering and Vibration Analysis
2011 - Springer Science+Business Media | Materials and Structures
Miguel Azenha, Rui Faria, Helena Figueiras,
The exothermal character of cement hydration reactions causes concrete to endure temperature changes during the first days after casting, with associated volumetric deformations that may induce undesired cracking. The capability to predict temperature evolution in concrete since casting is thus important to back decisions that avoid detrimental thermal cracking in concrete structures. Even though several approaches exist to model the early age behavior of concrete, the laboratory or in situ verification ...
Tópico(s): Fire effects on concrete materials
2011 - Elsevier BV | Construction and Building Materials
Devin P. Locke, LaDeana W. Hillier, Wesley C. Warren, Kim C. Worley, Lynne V. Nazareth, Donna M. Muzny, Shiaw‐Pyng Yang, Zhengyuan Wang, Asif Chinwalla, Pat Minx, Makedonka Mitreva, Lisa L. Cook, Kim D. Delehaunty, Catrina C. Fronick, Heather K. Schmidt, Lucinda A. Fulton, Robert S. Fulton, Joanne O. Nelson, Vincent Magrini, Craig Pohl, Tina Graves, Chris Markovic, Andy Cree, Huyen Dinh, Jennifer Hume, Christie Kovar, Gerald Fowler, Gerton Lunter, Stephen Meader, Andreas Heger, Chris P. Ponting, Tomás Marquès‐Bonet, Can Alkan, Lin Chen, Ze Cheng, Jeffrey M. Kidd, Evan E. Eichler, Simon White, Stephen M. J. Searle, Albert J. Vilella, Yuan Chen, Paul Flicek, Jian Ma, Brian J. Raney, Bernard Suh, Richard Burhans, Javier Herrero, David Haussler, Rui Faria, Olga Fernando, Fleur Darré, Domènec Farré, Élodie Gazave, Meritxell Oliva, Arcadi Navarro, Roberta Roberto, Oronzo Capozzi, Nicoletta Archidiacono, Giuliano Della Valle, Stefania Purgato, Mariano Rocchi, Miriam K. Konkel, Jerilyn A. Walker, Brygg Ullmer, Mark A. Batzer, Arian F. A. Smit, Robert Hubley, Claudio Casola, Daniel R. Schrider, Matthew W. Hahn, Vı́ctor Quesada, Xosé S. Puente, Gonzalo R. Ordóñez, Carlos López‐Otín, Tomáš Vinař, Broňa Brejová, Aakrosh Ratan, Robert S. Harris, Webb Miller, Carolin Kosiol, Heather A. Lawson, Vikas Taliwal, André L. Martins, Adam Siepel, Arindam RoyChoudhury, Xin Ma, Jeremiah D. Degenhardt, Carlos D. Bustamante, Ryan N. Gutenkunst, Thomas Mailund, Julien Y. Dutheil, Asger Hobolth, Mikkel Heide Schierup, Oliver A. Ryder, Yuko Yoshinaga, Pieter J. de Jong, George M. Weinstock, Jeffrey Rogers, Elaine R. Mardis, Richard A. Gibbs, Richard K. Wilson,
The genome of the Southeast Asian great ape or orang-utan has been sequenced — specifically a draft assembly of a Sumatran female individual and short-read sequence data from five further Sumatran and five Bornean orang-utan, Pongo abelii and Pongo pygmaeus, respectively. Orang-utan species appear to have split around 400,000 years ago, more recent than most previous estimates suggested, resulting in an average Bornean–Sumatran nucleotide identity of 99.68%. Structural evolution of the orang-utan ...
Tópico(s): HIV Research and Treatment
2011 - Nature Portfolio | Nature