Mary Anne Mercer, Susan Thompson, Rui Maria de Araújo,
Achieving the United Nations Millennium Development Goals for health will require that programs supporting health in developing countries focus on strengthening national health care systems. However, the dominant neoliberal model of development mandates reduced public spending on health and other social services, often resulting in increased funding for nongovernmental organizations (NGOs) at the expense of support for government systems. East Timor, later Timor-Leste, is an example of a post-crisis ...
Tópico(s): Global Security and Public Health
2014 - SAGE Publishing | International Journal of Health Services
Nelson Martins, Einar Heldal, J N Sarmento, Rui Maria de Araújo, E B Rolandsen, Patrick Kelly,
East Timor has undergone major political changes in the past 10 years. Tuberculosis (TB) control has flourished, despite chronic low tension conflict, a brief but intense period of high-level conflict and post-conflict reconstruction.To assess TB control in East Timor from 1996 to 2004.Data were collected from a variety of sources. Key TB programme indicators were analysed with reference to WHO targets to assess the performance of the three TB control programmes that operated during the study period. ...
Tópico(s): HIV/AIDS Impact and Responses
2006 - International Union Against Tuberculosis and Lung Disease | The International Journal of Tuberculosis and Lung Disease
Einar Heldal, Rui Maria de Araújo, Nelson Martins, J N Sarmento, Constantino Lopez,
This paper describes the key factors and remaining challenges for tuberculosis (TB) control programmes in complex emergencies.A complex emergency is "a humanitarian crisis in a country, region or society where there is total or considerable breakdown of authority resulting from internal or external conflict and which requires an international response that goes beyond the mandate or capacity of any single agency and/or the ongoing United Nations country programme."Some 200 million people are believed ...
Tópico(s): Peacebuilding and International Security
2007 - World Health Organization | Bulletin of the World Health Organization
Helen Henderson, Alexandrina Marques da Silva, Mariano da Silva, Helio Afranio Soares Xavier, Silvina Amaral Mendonca, Rui Maria de Araújo, Cathy Vaughan, Meghan A. Bohren,
Understanding the attitudes, knowledge, and practice of a health provider towards sexual and reproductive health (SRH) can provide valuable insight about how a primary health care system is functioning, and if it is meeting the SRH needs of its population. We conducted collaborative, participatory, and operational research to explore access to male methods of family planning in The Democratic Republic of Timor-Leste (Timor-Leste), from a health provider perspective. We conducted in-depth interviews ( ...
Tópico(s): Demographic Trends and Gender Preferences
2022 - Elsevier BV | SSM - Qualitative Research in Health
Andréia Rodrigues, Cláudia Corrêa de Araújo, Rui Carvalho, Maria Antonieta Melo, Luísa Pinto, Luís M. Graça,
Pseudoamniotic band syndrome (PABS) is an iatrogenic complication that causes entanglement of fetal parts in a constrictive sheet of detached or ruptured amniotic membrane after an invasive procedure, namely amniocentesis, amnioreduction or septostomy in twins. The incidence and risk factors for PABS after fetoscopy-guided laser have not been documented [Winer et al.: Am J Obstet Gynecol 2008;198:393.e1–393.e5]. We report a case of monochorionic biamniotic twin pregnancy submitted to selective fetoscopic ...
Tópico(s): Prenatal Screening and Diagnostics
2012 - Karger Publishers | Fetal Diagnosis and Therapy
Daniela Rodrigues, Joana Pinto, Ana Margarida Araújo, Cármen Jerónimo, Rui Henrique, Maria de Lourdes Bastos, Paula Guedes de Pinho, Márcia Carvalho,
Previous studies have shown that metabolomics can be a useful tool to better understand the mechanisms of carcinogenesis; however, alterations in biochemical pathways that lead to bladder cancer (BC) development have hitherto not been fully investigated. In this study, gas chromatography-mass spectrometry (GC-MS)-based metabolomics was applied to unveil the metabolic alterations between low-grade and high-grade BC cultured cell lines. Multivariable analysis revealed a panel of metabolites responsible ...
Tópico(s): Gut microbiota and health
2019 - Multidisciplinary Digital Publishing Institute | Metabolites
Produção Nacional
Revisado por pares
Carlos Henrique Medeiros de Araújo, Daniela Nogueira, Maria Cristina Picinato Medeiros de Araújo, Wellington P. Martins, Rui Alberto Ferriani, Rosana Maria dos Reis,
ObjectiveTo compare oocyte maturation, fertilization and cleavage rates, and embryonic developmental quality after culture of human immature oocytes from polycystic ovary syndrome (PCOS) patients in human tubal fluid (HTF) or tissue culture medium (TCM) 199.DesignProspective, randomized, controlled trial.SettingUniversity hospital.Patient(s)Thirteen women undergoing 23 in vitro maturation cycles, from whom 119 oocytes were retrieved.Intervention(s)Cumulus-enclosed germinal vesicle–stage oocytes matured ...
Tópico(s): Reproductive Health and Technologies
2008 - Elsevier BV | Fertility and Sterility
Ana Rita Lima, Ana Margarida Araújo, Joana Pinto, Cármen Jerónimo, Rui Henrique, Maria de Lourdes Bastos, Márcia Carvalho, Paula Guedes de Pinho,
Prostate cancer (PCa) is an important health problem worldwide. Diagnosis and management of PCa is very complex because the detection of serum prostate specific antigen (PSA) has several drawbacks. Metabolomics brings promise for cancer biomarker discovery and for better understanding PCa biochemistry. In this study, a gas chromatography-mass spectrometry (GC-MS) based metabolomic profiling of PCa cell lines was performed. The cell lines include 22RV1 and LNCaP from PCa with androgen receptor (AR) expression, ...
Tópico(s): Cancer, Lipids, and Metabolism
2018 - Multidisciplinary Digital Publishing Institute | Metabolites
Ana Rita Lima, Ana Margarida Araújo, Joana Pinto, Cármen Jerónimo, Rui Henrique, Maria de Lourdes Bastos, Márcia Carvalho, Paula Guedes de Pinho,
Serum prostate-specific antigen (PSA) is currently the most used biomarker in clinical practice for prostate cancer (PCa) detection. However, this biomarker has several drawbacks. In this work, an untargeted gas chromatography-mass spectrometry (GC-MS)-based metabolomic profiling of PCa cells was performed to prove the concept that metabolic alterations might differentiate PCa cell lines from normal prostate cell line. For that, we assessed the differences in volatile organic compounds (VOCs) profile ...
Tópico(s): Analytical Chemistry and Chromatography
2018 - Nature Portfolio | Scientific Reports
Daniela Rodrigues, Joana Pinto, Ana Margarida Araújo, Sara Monteiro‐Reis, Cármen Jerónimo, Rui Henrique, Maria de Lourdes Bastos, Paula Guedes de Pinho, Márcia Carvalho,
Tópico(s): Olfactory and Sensory Function Studies
2018 - Springer Science+Business Media | Metabolomics
Produção Nacional
Revisado por pares
Gustavo Salata Romão, Maria Cristina Picinato Medeiros de Araújo, Anderson Sanches de Melo, Paula Andrea Navarro, Rui Alberto Ferriani, Rosana Maria dos Reis,
ObjectiveTo assess the impact of the mean oocyte diameter (MOD) on occurrence of fertilization and embryo quality in assisted reproduction cycles.DesignProspective observational study.SettingSector of Human Reproduction of the University Hospital, Faculty of Medicine of Ribeirão Preto, University of São Paulo (HCFMRP-USP).Patient(s)Thirty-five women undergoing intracytoplasmic sperm injection (ICSI) at the University Hospital of Ribeirão Preto from May to October 2007.Intervention(s)MOD assessment. ...
Tópico(s): Assisted Reproductive Technology and Twin Pregnancy
2009 - Elsevier BV | Fertility and Sterility
Produção Nacional
Revisado por pares
Ewerton Marinho da Costa, Maria Goretti Araújo de Lima, Rui Sales Júnior, Adriano Cavalleri, Elton Lucio Araújo,
The aim of this research was to report the occurrence of two species of thrips in watermelon crops in the semiarid region of Rio Grande do Norte, Brazil. From August to September 2011, we performed weekly sampling of thrips in a commercial watermelon production area with 10,000m2, using 20 Moericke traps. We captured a total of 431 thrips, belonging to Frankliniella schultzei (Trybom) (Thripidae) and Haplothrips gowdeyi (Franklin) (Phlaeothripidae). This is the first report of H. gowdeyi in watermelon ...
Tópico(s): Agronomic Practices and Intercropping Systems
2014 - UNIVERSIDADE FEDERAL DE SANTA MARIA | Ciência Rural
Produção Nacional
Revisado por pares
Daniele Ribeiro de Araújo, Cristina Padula, Cíntia Maria Saia Cereda, Giovana Radomille Tófoli, Rui Barbosa de Brito, Eneida de Paula, Sara Nicoli, Patrizia Santi,
Tópico(s): Advancements in Transdermal Drug Delivery
2010 - Springer Science+Business Media | Pharmaceutical Research
Rui Borralho, Chris Stoate, Maria Elisabeth de Araújo,
The main factors affecting the spring distribution of Red-legged Partridges Alectoris rufa were evaluated in a 1550-km2 landscape of southern Portugal, where different arable systems and hunting regimes were implemented. Partridge surveys were performed in April 1995 along 90, 250-m transects. Partridge locations and a number of environmental variables were incorporated and manipulated in a vector-based GIS. A multivariate logistic model of partridge detection was fitted using forward stepwise selection, ...
Tópico(s): Animal Disease Management and Epidemiology
2000 - Taylor & Francis | Bird Study
Produção Nacional
Revisado por pares
Giovana Radomille Tófoli, Cíntia Maria Saia Cereda, Daniele Ribeiro de Araújo, Eneida de Paula, Rui Barbosa Brito Júnior, José Pedrazzoli Júnior, Eduardo C. Meurer, Fábio Alessandro Proença Barros, Francisco Carlos Groppo, Maria Cristina Volpato, José Ranali,
The pharmacokinetics and the local toxicity of commercial and liposome-encapsulated mepivacaine formulations injected intra-orally in rats were studied. Animals were divided in groups (n = 4–6) and treated with 0.1 mL of the formulations: 2% mepivacaine with 1:100,000 epinephrine (MVC2%EPI), 3% mepivacaine (MVC3%), and 2% liposome-encapsulated mepivacaine (MVCLUV). The results showed that the 2% liposome-encapsulated mepivacaine reduced Cmax, prolonged AUC0–∞ and t1/2 compared with 3% plain and 2% vasoconstritor- ...
Tópico(s): Dental Anxiety and Anesthesia Techniques
2010 - Taylor & Francis | Drug Delivery
Paula C. Peixoto, Paula Ministro, A. Sadio, Eugénia Cancela, Ricardo Araújo, Joana Machado, António Castanheira, Américo T. Silva, Rui D. Nunes, Maria Teresa Feital de Carvalho, António F. Caldas,
The esophagus's involvement in tuberculosis is rare, and the clinical presentation may mimic an esophageal carcinoma. A 70-year-old man who is immunocompetent and with dysphagia and weight loss over the previous 3 months was referred to our department with imaging findings of an esophageal cancer. Esophagoscopy showed 2 shallow, longitudinal ulcers with irregular edges in the mid esophagus. Bronchofibroscopy revealed an ulcer of shaded borders and a whitish center in the right bronchus. Histologic ...
Tópico(s): Infectious Diseases and Tuberculosis
2009 - Elsevier BV | Gastrointestinal Endoscopy
Filipa Amaro, Joana Pinto, Sílvia Rocha, Ana Margarida Araújo, Vera Miranda‐Gonçalves, Cármen Jerónimo, Rui Henrique, Maria de Lourdes Bastos, Márcia Carvalho, Paula Guedes de Pinho,
The identification of noninvasive biomarkers able to detect renal cell carcinoma (RCC) at an early stage remains an unmet clinical need. The recognition that altered metabolism is a core hallmark of cancer boosted metabolomic studies focused in the search for cancer biomarkers. The present work aims to evaluate the performance of the volatile metabolites present in the extracellular medium to discriminate RCC cell lines with distinct histological subtypes (clear cell and papillary) and metastatic ...
Tópico(s): Essential Oils and Antimicrobial Activity
2020 - Multidisciplinary Digital Publishing Institute | Metabolites
Produção Nacional
Narcísio Cabral de Araújo, Mônica de Amorim Coura, Rui de Oliveira, Celeide Maria Belmont Sabino Meira, Suenildo Jósemo Costa Oliveira,
CULTIVO HIDROPÔNICO DE MILHO FERTIRRIGADO COM URINA HUMANA COMO FONTE ALTERNATIVA DE NUTRIENTES NARCÍSIO CABRAL DE ARAÚJO1; MÔNICA DE AMORIM COURA2; RUI DE OLIVEIRA3; CELEIDE MARIA BELMONT SABINO4 E SUENILDO JÓSEMO COSTA OLIVEIRA5 1 Eng. Sanitarista e Ambiental, Mestre em Eng. Civil e Ambiental e Doutorando em Eng. Agrícola, Universidade Federal de Campina Grande - UFCG, Campina Grande, PB. E-mail: narcisioaraujo@gmail.com2 Química, Mestra em Eng. Civil, Doutora em Recursos Naturais, Professora Associada ...
Tópico(s): Growth and nutrition in plants
2015 - UNIVERSIDADE EST.PAULISTA JÚLIO DE MESQUITA FILHO | Irriga
Produção Nacional
Revisado por pares
Maria Cristina Picinato Medeiros de Araújo, Aparecida Emiko Hirata, José Cipolla‐Neto, Rui Curi, Carla Roberta de Oliveira Carvalho, Gabriel Forato Anhê, Ângelo Rafael Carpinelli,
Abstract: Melatonin diminishes insulin release through the activation of MT1 receptors and a reduction in cAMP production in isolated pancreatic islets of neonate and adult rats and in INS‐1 cells (an insulin‐secreting cell line). The pancreas of pinealectomized rats exhibits degenerative pathological changes with low islet density, indicating that melatonin plays a role to ensure the functioning of pancreatic beta cells. By using immunoprecipitation and immunoblotting analysis we demonstrated, in ...
Tópico(s): Circadian rhythm and melatonin
2007 - Wiley | Journal of Pineal Research
Produção Nacional
Revisado por pares
Aderbal S. Aguiar, Andréa L. Araújo, Thaise R. da-Cunha, Ana Elisa Speck, Zuleide Maria Ignácio, Nelson De-Mello, Rui Daniel Prediger,
Previous studies have shown that cognitive deficits precede the classical motor symptoms seen in Parkinson's disease (PD) and that physical exercise may exert beneficial effects on PD. We have recently verified that the monoamine-depleting drug reserpine - at doses that do not modify motor function - impairs memory processes in rats. Here, we evaluated the potential of physical exercise to improve cognitive and motor deficits induced by reserpine. Adult Wistar rats were assigned to six groups: (1) untrained- ...
Tópico(s): Neuroscience and Neuropharmacology Research
2009 - Elsevier BV | Brain Research Bulletin
Produção Nacional
Revisado por pares
I.A. Araujo Penna, Paulo Roberto Bastos Canella, Rosana Maria dos Reis, Marcos Felipe Silva de Sá, Rui Alberto Ferriani,
BACKGROUND: The present study assessed the effects of low-dose acarbose on obese patients with polycystic ovarian syndrome (PCOS). METHODS: A double-blind placebo-controlled study was conducted on 30 obese hyperinsulinaemic women with PCOS treated with 150 mg/day acarbose or placebo for 6 months. The women were evaluated for hirsutism, menstrual regularity, body mass index (BMI), insulin resistance and glucose tolerance, sex hormone-binding globulin (SHBG), LH, FSH, testosterone and androstenedione, ...
Tópico(s): Ovarian cancer diagnosis and treatment
2005 - Oxford University Press | Human Reproduction
Produção Nacional
Revisado por pares
L.A. Dib, Maria Cristina Picinato Medeiros de Araújo, Roberta Cristina Giorgenon, Gustavo Salata Romão, Rui Alberto Ferriani, Paula Andrea Navarro,
The objectives of this prospective study were to evaluate the nuclear maturation stage and the presence and location of meiotic spindles of in vivo matured oocytes from infertile women with and without endometriosis (male or tubal causes of infertility) undergoing stimulated cycles for intracytoplasmic sperm injection (ICSI). We also compared the ICSI outcomes among groups. We analyzed the meiotic spindles of oocytes from 36 patients with endometriosis I/II, 24 with endometriosis III/IV, and 60 without ...
Tópico(s): Reproductive System and Pregnancy
2012 - Springer Nature | Reproductive Sciences
Produção Nacional
Revisado por pares
Claudio Sabbatini Capella Lopes, Daniele Barreto Teixeira, Bernardo Ferreira Braz, Ricardo Erthal Santelli, Livia Vieira Araújo de Castilho, José Gregório Cabrera Gomez, Rui de Paula Vieira de Castro, Lucy Seldin, Denise Maria Guimarães Freire,
Tópico(s): Microplastics and Plastic Pollution
2020 - Springer Science+Business Media | International Journal of Environmental Science and Technology
Susana Daniela Sousa Fernandes, Catarina Araújo da Silva Ribeiro, Maria Filomena de Jesus Raposo, Rui Morais, Alcina M. M. B. Morais,
The objective was to study the effect of alginate coating on polyphenol oxidase (PPO) activity and colour of 'Starking' apple cubes during dehydration with hot air. Apple cubes were dehydrated at 20oC, 35oC, or 40oC, with a parallel airflow. Analysis of PPO activity, colour (L*, a*, b*) and dry matter were performed along the dehydration process at each temperature. All samples presented a peak in relative PPO activity in the beginning of the drying. Exponential models fitted well the experimental ...
Tópico(s): Phytochemicals and Antioxidant Activities
2011 - Scientific Research Publishing | Food and Nutrition Sciences
Produção Nacional
Revisado por pares
Luciana de Araújo Pimenta, Maíra Estanislau Soares de Almeida, Marisa Langeani Bretones, Maria Cristina Cirillo, Rui Curi, Sandra Coccuzzo Sampaio,
Crotoxin (CTX) is the primary toxin of South American rattlesnake Crotalus durissus terrificus venom. CTX reduces tumour mass, and tumour cell proliferation and these effects seem to involve the formation of new vessels. Angiogenesis has a key role in tumour growth and progression and is regulated by macrophage secretory activity. Herein, the effect of CTX on macrophage secretory activity associated with angiogenesis was investigated in vitro. Thymic endothelial cells (EC) were incubated in the presence ...
Tópico(s): Neutrophil, Myeloperoxidase and Oxidative Mechanisms
2019 - Nature Portfolio | Scientific Reports
Maria Salomé Carvalho, Rita Calé, Pedro de Araújo Gonçalves, Hugo Vinhas, Luís Raposo, Rui Campante Teles, Cristina Martins, Henrique Mesquita Gabriel, Hélder Pereira, Manuel Almeida,
Background: Fewer bleeding complications and early ambulation make radial access a privileged route for cardiac catheterization.However, transradial (TR) approach is not always successful, requiring its conversion into femoral access.Objectives: To evaluate the rate of conversion from radial into femoral access in cardiac catheterization and to identify its predictors.Methods: Prospective dual-center registry, including 7632 consecutive patients undergoing catheterization via the radial access between ...
Tópico(s): Venous Thromboembolism Diagnosis and Management
2015 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Produção Nacional
Maria Estela Silva Andrade, Amanda Carolina Hora da Silva, Paula Teixeira Araújo, Rui Manoel de Bastos Vieira, Luís Paulo de Carvalho Piassi,
O presente artigo visa apresentar os resultados parciais de uma aplicação realizada no grupo/projeto L.I.R.A. sobre a percepção de um grupo de meninas a respeito do papel delas na sociedade e nas ciências, bem como refletir sobre como essa percepção, tanto de si quanto do outro, afeta a construção de suas identidades. A análise dos dados foi feita através de uma metodologia qualitativa com a aplicação de um grupo focal que teve como foco o discurso das participantes sobre o tema pesquisado. Os resultados ...
Tópico(s): Education Pedagogy and Practices
2019 - | Interfaces Científicas - Humanas e Sociais
Produção Nacional
Revisado por pares
Daiana Cristina Chielli Pedroso, Viviane Paiva Santana, Flávia S. Donaires, Maria Cristina Picinato Medeiros de Araújo, Roberta Cristina Giorgenon, Bárbara A. Santana, R.N. Pimentel, David L. Keefe, Rodrigo T. Calado, Rui Alberto Ferriani, Cristiana Libardi Miranda Furtado, Rosana Maria dos Reis,
Tópico(s): Sperm and Testicular Function
2020 - Springer Nature | Reproductive Sciences
Helen Henderson, Alexandrina Marques da Silva, Mariano da Silva, Helio Afranio Soares Xavier, Silvina Amaral Mendonca, Rui Maria de Araújo, Cathy Vaughan, Meghan A. Bohren,
Understanding and respecting different linguistic and socio-cultural needs of health service users is critical to design, adapt and provide appropriate health services. We explored access to male family planning methods in The Democratic Republic of Timor-Leste, a linguistically and culturally diverse nation, by conducting 14 participatory group discussions (PGDs) with 175 participants across seven municipalities. Participants (84 men and 91 women, aged 18 to 72) spoke 13 different languages. PGDs ...
Tópico(s): Migration, Health and Trauma
2022 - SAGE Publishing | Qualitative Health Research
Produção Nacional
Revisado por pares
Vanessa Alves Lima Rocha, Livia Vieira Araújo de Castilho, Rui de Paula Vieira de Castro, Douglas B. Teixeira, Augusto Vieira Magalhães, José Gregório Cabrera Gomez, Denise Maria Guimarães Freire,
Abstract Rhamnolipids (RMLs) have more effectiveness for specific uses according to their homologue proportions. Thus, the novelty of this work was to compare mono‐RMLs and di‐RMLs physicochemical properties on microbial enhanced oil recovery (MEOR) applications. For this, RML produced by three strains of Pseudomonas aeruginosa containing different homologues proportion were used: a mainly mono‐RMLs producer (mono‐RMLs); a mainly di‐RMLs producer (di‐RMLs), and the other one that produces relatively ...
Tópico(s): Hydrocarbon exploration and reservoir analysis
2020 - American Chemical Society | Biotechnology Progress