Nancy Wuenderlich, Kristina Heinonen, Amy L. Ostrom, Lia Patrício, Rui Sousa, Chris Voss, Jos Lemmink,
Purpose – The purpose of this paper is to craft a future research agenda to advance smart service research and practice. Smart services are delivered to or via intelligent objects that feature awareness and connectivity. For service researchers and managers, one of the most fascinating aspects of smart service provision is that the connected object is able to sense its own condition and its surroundings and thus allows for real-time data collection, continuous communication and interactive feedback. ...
Tópico(s): Customer Service Quality and Loyalty
2015 - Emerald Publishing Limited | Journal of Services Marketing
Luísa Correia Martins, Rita Lourenço, Susana Cordeiro, Nuno Carvalho, Inês Mendes, Marisa Dias Rolan Loureiro, Miguel Patrício, Rui Anjos,
Tópico(s): Congenital Diaphragmatic Hernia Studies
2015 - Springer Science+Business Media | European Journal of Pediatrics
Produção Nacional
Delmo Alves de Moura, Marcelo Luiz Patrício, Rui Carlos Botter,
Este trabalho faz uma análise dos principais terminais portuários brasileiro, especialmente no porto de Santos, em São Paulo, relacionado com automação das operações portuárias na movimentação de contêineres. O trabalho foi realizado através de pesquisa em campo para levantamento da situação atual dos terminais em Santos visando descrever o grau de automação na movimentação, transbordo e armazenagem de contêineres. A pesquisa foi realizada através de um questionário em campo e se realizou uma revisão ...
Tópico(s): Maritime Ports and Logistics
2016 - UNIVERSIDADE TECNOLÓGICA FEDERAL DO PARANÁ | Revista Gestão Industrial
Luís Maia Carneiro, António Lucas Soares, Rui Patrício, Américo Azevedo, Jorge Pinho de Sousa,
This paper presents part of the findings of a research project aiming at characterising high-performance collaborative business networks and at defining the conditions required for their creation and management. The project adopted a multiple case study research strategy and three different business networks are presented in this paper. Empirical studies have been performed in Northern Portugal. The results of the study include operational definitions based on a comprehensive literature review, ...
Tópico(s): Outsourcing and Supply Chain Management
2012 - Taylor & Francis | International Journal of Computer Integrated Manufacturing
Neus Morera, Ferry Hagen, Carles Juan‐Sallés, Carlos Trucharte Artigas, Rui Patrício, Juan Ignacio Serra, Ma Francisca Colom,
Cryptococcus gattii is a pathogenic environmental yeast that is considered to be emerging in different areas of the world including the Mediterranean Basin. Exposure to infection might be more likely in animals than in human beings, given their closer relationship with the natural habitat of the yeast, vegetation and soil. Thus, animals, and especially pets, can act as indicators of the presence of this yeast in a determined area. Domestic ferrets (Mustela putorius furo) have become common pets in ...
Tópico(s): Antifungal resistance and susceptibility
2014 - Springer Science+Business Media | Mycopathologia
Purpose The purpose of this paper is to explain the link between gamification and innovation and describes the use of a particular gamified method and tool, which helps teams get committed and engaged in idea development. The goal is to provide valuable insights on how gamification can accelerate innovation. Design/methodology/approach A study was conducted using a combination of qualitative methods: workshops based on action research method followed by semi-structured interviews with workshop participants ...
Tópico(s): Motivation and Self-Concept in Sports
2017 - Emerald Publishing Limited | World Journal of Science Technology and Sustainable Development
Rui Patrício, António Carrizo Moreira, Francesco Zurlo, Michele Melazzini,
This paper aims to explore the main implications of gamification approaches to collaborative innovation and particularly to co‐creation, i.e. the interaction and interchange of ideas between users, customers, suppliers and other actors in the development of new solutions. Despite the few approaches attempting to make co‐creation more ludic and accessible, researchers have yet to analyse the link between gamification and co‐creation in an extensive manner. In order to better understand this unexplored ...
Tópico(s): Open Source Software Innovations
2020 - Wiley | Creativity and Innovation Management
Rui Patrício, António Carrizo Moreira, Francesco Zurlo,
Purpose The paper aims to explore the relationship between gamification and design thinking approach to innovation in the context of the early stage of innovation process (ESoIP). Design thinking is conceptually appropriate to support innovative, complex and uncertain business environments. Still, its practices have demonstrated some difficulties in managing the ESoIP, such as lack of structure and clarity around goals. This paper argues that gamification can enhance and complement design thinking ...
Tópico(s): Virtual Reality Applications and Impacts
2020 - Emerald Publishing Limited | European Journal of Innovation Management
Rui Patrício, António Carrizo Moreira, Francesco Zurlo,
The paper examines the relationship between gamification – the use of game elements in non-gaming contexts – and innovation teams' outcomes. It builds on psychological and teamwork theories, arguing that gamification overcomes collaboration issues and generates multiple positive outcomes, particularly in coordination, alignment, engagement, and teams' motivation. The research follows a qualitative theory-driven using a case study of an innovation project. The conceptual model built through the findings ...
Tópico(s): Motivation and Self-Concept in Sports
2022 - Elsevier BV | International Journal of Innovation Studies
Rui Patrício, António Carrizo Moreira, Francesco Zurlo,
Despite the growing adoption and acceptance of gamification approaches among firms, the relationship between gamification and the early stage of innovation is confusing and deserves further attention in order to produce added‐value exploratory knowledge. This paper puts forward the idea that gamification approaches can support the early stage of innovation by making a cross‐comparison of published case studies of firms where gamification was used to address innovation challenges, e.g. use of gamification ...
Tópico(s): Virtual Reality Applications and Impacts
2018 - Wiley | Creativity and Innovation Management
João Tedim, Sónia G. Patrício, R. Bessada, Rui Morais, Carla Sousa, Manuel B. Marques, Cristina Freire,
Abstract Third‐order nonlinear and linear optical properties ofnickel(II) and copper(II) complexes with salen ligands, functionalised with electron donor/acceptor groups (DA‐salen), have been investigated in solution by the Z‐scan technique using an Nd:YAG laser ( λ inc = 1064 nm) and UV/Vis spectroscopy. The [M(DA‐ salen )] complexes exhibit positive nonresonant nonlinear refractive indexes ( n 2 I ) in the range27.0–8.50 · 10 –21 m 2 W –1 and nonlinear absorption coefficients ( α 2 I ) within the range 1.80–26.0 · 10 – ...
Tópico(s): Porphyrin and Phthalocyanine Chemistry
2006 - Wiley | European Journal of Inorganic Chemistry
José Pedro Henriques Patrício, Jorge Barbosa, Rui Miguel Monteiro Ramos, Nuno Antunes, Pedro Carlos Santos de Melo,
Tópico(s): Antiplatelet Therapy and Cardiovascular Diseases
2013 - Adis, Springer Healthcare | Clinical Drug Investigation
Produção Nacional
Revisado por pares
Leandro H. P. Assis, Rui Milton Patrício da Silva-Júnior, Luciano G. Dolce, Marcos Rodrigo Alborghetti, Rodrigo V. Honorato, Andrey Fabricio Ziem Nascimento, Talita Diniz Melo‐Hanchuk, Daniel Maragno Trindade, C.C.C. Tonoli, C. Santos, Paulo Sérgio Lopes de Oliveira, R E Larson, Jörg Kobarg, Enilza Maria Espreáfico, P.O. Giuseppe, M.T. Murakami,
Abstract Myosin Va (MyoVa) is an actin-based molecular motor abundantly found at the centrosome. However, the role of MyoVa at this organelle has been elusive due to the lack of evidence on interacting partners or functional data. Herein, we combined yeast two-hybrid screen, biochemical studies and cellular assays to demonstrate that MyoVa interacts with RPGRIP1L, a cilia-centrosomal protein that controls ciliary signaling and positioning. MyoVa binds to the C2 domains of RPGRIP1L via residues located ...
Tópico(s): Genetic Syndromes and Imprinting
2017 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Willian Lazarini-Lopes, Raquel A. Do Val-da Silva, Rui Milton Patrício da Silva-Júnior, João Pereira Leite, Norberto Garcia‐Cairasco,
Epilepsy is a neurological disorder characterized by the presence of seizures and neuropsychiatric comorbidities. Despite the number of antiepileptic drugs, one-third of patients did not have their seizures under control, leading to pharmacoresistance epilepsy. Cannabis sativa has been used since ancient times in Medicine for the treatment of many diseases, including convulsive seizures. In this context, Cannabidiol (CBD), a non-psychoactive phytocannabinoid present in Cannabis, has been a promising ...
Tópico(s): Diet, Metabolism, and Disease
2020 - Elsevier BV | Neuroscience & Biobehavioral Reviews
Produção Nacional
Revisado por pares
Willian Lazarini-Lopes, Rui Milton Patrício da Silva-Júnior, Gabriel Servilha‐Menezes, Raquel A. Do Val-da Silva, Norberto Garcia‐Cairasco,
The endocannabinoid system (ECS) is related to several physiological processes, associated to the modulation of brain excitability, with impact in the expression of susceptibility and control of epileptic seizures. The cannabinoid receptor type 1 (CB1R) is widely expressed in the brain, especially in forebrain limbic structures. Changes in CB1R expression are associated with epileptic seizures in animal models and humans. The Wistar Audiogenic Rat (WAR) strain is a genetic model of epilepsy capable ...
Tópico(s): Sleep and Wakefulness Research
2020 - Frontiers Media | Frontiers in Behavioral Neuroscience
Produção Nacional
Revisado por pares
Suélen Santos Alves, Rui Milton Patrício da Silva-Júnior, Gabriel Servilha‐Menezes, Jan Homolak, Melita Šalković‐Petrišić, Norberto Garcia‐Cairasco,
Almost 115 years ago, Alois Alzheimer described Alzheimer's disease (AD) for the first time. Since then, many hypotheses have been proposed. However, AD remains a severe health public problem. The current medical approaches for AD are limited to symptomatic interventions and the complexity of this disease has led to a failure rate of approximately 99.6%in AD clinical trials. In fact, no new drug has been approved for AD treatment since 2003. These failures indicate that we are failing in mimicking ...
Tópico(s): Natural Antidiabetic Agents Studies
2021 - IOS Press | Journal of Alzheimer s Disease
Produção Nacional
Revisado por pares
Willian Lazarini-Lopes, Raquel A. Do Val-da Silva, Rui Milton Patrício da Silva-Júnior, Gleice Kelli Silva-Cardoso, Christie Ramos Andrade Leite‐Panissi, João Pereira Leite, Norberto Garcia‐Cairasco,
Cannabidiol (CBD) is a marijuana compound implicated in epilepsy treatment in animal models and pharmacoresistant patients. However, little is known about chronic CBD administration's effects in chronic models of seizures, especially regarding its potential antiepileptogenic effects. In the present study, we combined a genetic model of epilepsy (the Wistar Audiogenic Rat strain - WARs), a chronic protocol of seizures (the audiogenic kindling - AuK), quantitative and sequential behavioral analysis (neuroethology), ...
Tópico(s): Epilepsy research and treatment
2021 - Elsevier BV | Epilepsy & Behavior
Produção Nacional
Revisado por pares
Suélen Santos Alves, Gabriel Servilha‐Menezes, Letícia Rossi, Rui Milton Patrício da Silva-Júnior, Norberto Garcia‐Cairasco,
Since glucose reuptake by neurons is mostly independent of insulin, it has been an intriguing question whether insulin has or not any roles in the brain. Consequently, the identification of insulin receptors in the central nervous system has fueled investigations of insulin functions in the brain. It is also already known that insulin can influence glucose reuptake by neurons, mostly during activities that have the highest energy demand. The identification of high density of insulin receptors in ...
Tópico(s): Neurological Disorders and Treatments
2023 - Elsevier BV | Neuroscience & Biobehavioral Reviews
Produção Nacional
Revisado por pares
Rui Milton Patrício da Silva-Júnior, Ana Carolina Bueno, Clarissa Silva Martins, Fernanda Coelli-Lacchini, Jorge Guilherme Okanobo Ozaki, Danillo Cunha de Almeida-e-Silva, Junier Marrero-Gutiérrez, Antônio Carlos dos Santos, Carlos Garcia-Peral, Hélio Rubens Machado, Marcelo Volpon Santos, Paula Lamparelli Elias, Ayrton Custódio Moreira, Leandro M. Colli, Ricardo Z. N. Vêncio, Sonir Roberto Rauber Antonini, Margaret de Castro,
Abstract Objective To explore pituitary tumors by methylome and transcriptome signatures in a heterogeneous ethnic population. Methods In this retrospective cross-sectional study, clinicopathological features, methylome, and transcriptome were evaluated in pituitary tumors from 77 patients (61% women, age 12-72 years) followed due to functioning (FPT: GH-secreting n = 18, ACTH-secreting n = 14) and nonfunctioning pituitary tumors (NFPT, n = 45) at Ribeirao Preto Medical School, University of São Paulo. Results ...
Tópico(s): Adrenal and Paraganglionic Tumors
2022 - Oxford University Press | The Journal of Clinical Endocrinology & Metabolism
Patrício Aguiar, Olga Azevedo, Rui Pinto, Jacira Marino, Carlos Cardoso, Nuno Sousa, Damião Cunha, Derralynn Hughes, José Luís Ducla Soares,
Background Cardiomyopathy is a major determinant of overall Fabry disease ( FD ) prognosis, with the worst outcomes in patients with myocardial fibrosis. Late gadolinium enhancement is currently the gold standard for evaluation of replacement myocardial fibrosis; however, this event is irreversible, thus identification of biomarkers of earlier diffuse fibrosis is paramount. Methods and Results Type I collagen synthesis and degradation biomarkers (PICP [carboxyterminal propeptide of procollagen type I], ...
Tópico(s): Trypanosoma species research and implications
2018 - Wiley | Journal of the American Heart Association
Pedro Arezes, João Santos Baptista, Mónica P. Barroso, ́Paula Carneiro, Patrício Cordeiro, Nélson Costa, Rui B. Melo, A. Sérgio Miguel, Gonçalo Perestrelo,
This edited book reports on research done at universities and other institutions in the field of occupational safety and health (OSH), and on some practical case studies developed by OSH practitioners alike, and covers cutting-edge OSH issues in a global application context
Tópico(s): Occupational Health and Safety Research
2020 - Springer International Publishing | Studies in systems, decision and control
Pedro Arezes, João Santos Baptista, Mónica P. Barroso, ́Paula Carneiro, Patrício Cordeiro, Nélson Costa, Rui B. Melo, A. Sérgio Miguel, Gonçalo Perestrelo,
This book reports on research done at universities and other institutions in the field of occupational safety and health (OSH), and on some practical case studies developed by OSH practitioners alike, and covers cutting-edge OSH issues in a global application context
Tópico(s): Occupational Health and Safety Research
2019 - Springer International Publishing | Studies in systems, decision and control
Produção Nacional
Revisado por pares
Carlos Roberto Porto Dechandt, Gustavo Duarte Ferrari, Jonathas Rodrigo dos Santos, José Antônio Cortes de Oliveira, Rui Milton Patrício da Silva-Júnior, Alexandra Olímpio Siqueira Cunha, Norberto Garcia‐Cairasco, Luciane C. Alberici,
The Wistar Audiogenic Rat (WAR) strain is a genetic model of epilepsy, specifically brainstem-dependent tonic-clonic seizures, triggered by acute auditory stimulation. Chronic audiogenic seizures (audiogenic kindling) mimic temporal lobe epilepsy, with significant participation of the hippocampus, amygdala, and cortex. The objective of the present study was to characterize the mitochondrial energy metabolism in hippocampus and cortex of WAR and verify its relationship with seizure severity. Hippocampus ...
Tópico(s): Mitochondrial Function and Pathology
2019 - Frontiers Media | Frontiers in Neurology
Patrício Aguiar, Olga Azevedo, Rui Pinto, Jacira Marino, Robert J. Baker, Carlos Cardoso, José Luís Ducla Soares, Derralynn Hughes,
Renal involvement in Fabry disease is a major determinant of overall disease prognosis and early enzyme replacement therapy seems effective in preventing progression of kidney injury. Gb3 storage, glomerular sclerosis and tubulo-interstitial fibrosis may occur with minimal or no changes on standard renal tests, hence alternative markers of renal dysfunction are crucial. In this study we compared several biomarkers with albuminuria in the identification of incipient Fabry nephropathy and their diagnostic ...
Tópico(s): Cellular transport and secretion
2017 - Elsevier BV | Molecular Genetics and Metabolism
Produção Nacional
Ilana de França Azevedo, Rui Milton Patrício da Silva-Júnior, Audrey Violeta Martins de Vasconcelos, Washington Batista das Neves, Fárida Coeli de Barros Correia Melo, Raul Antônio Morais Melo,
This study investigated the occurrence of the p190 and p210 breakpoint cluster region-Abelson (BCR-ABL) rearrangements in adults with acute lymphoblastic leukemia and possible associations with clinical and laboratory characteristics and survival. Forty-one over 18-year-old patients with acute lymphoblastic leukemia of both genders followed-up between January 2008 and May 2012 were included in this study. Clinical and laboratory data were obtained from the medical charts of the patients. Reverse ...
Tópico(s): Chronic Lymphocytic Leukemia Research
2014 - Elsevier BV | Revista Brasileira de Hematologia e Hemoterapia
Pedro Rio, Rubén Ramos, Tiago Pereira‐da‐Silva, Carlos Barbosa, Duarte Cacela, António Fiarresga, Lídia de Sousa, Ana Abreu, Lino Patrício, L Bernardes, Rui Cruz Ferreira,
PurposeNoninvasive ischemia testing (NIST) is recommended for most patients suspected to have stable coronary artery disease (CAD) before invasive coronary angiography (ICA). We sought to assess the diagnostic predictive ability of NIST over clinical risk profiling in a contemporary sample of patients undergoing the currently recommended diagnostic triage strategy. MethodsFrom 2006 to 2011, 2,600 consecutive patients without known CAD undergoing elective ICA in a single tertiary-care center were retrospectively ...
Tópico(s): Coronary Interventions and Diagnostics
2015 - Wichtig | Heart International
André Patrício, Rafael S. Costa, Rui Henriques,
Background In the face of the current COVID-19 pandemic, the timely prediction of upcoming medical needs for infected individuals enables better and quicker care provision when necessary and management decisions within health care systems. Objective This work aims to predict the medical needs (hospitalizations, intensive care unit admissions, and respiratory assistance) and survivability of individuals testing positive for SARS-CoV-2 infection in Portugal. Methods A retrospective cohort of 38,545 ...
Tópico(s): COVID-19 and healthcare impacts
2021 - JMIR Publications | Journal of Medical Internet Research
Inês Cardoso, Luísa Álvares Pereira, Célia da Graça Lopes, Rui Patrício Andrade Pereira Lopes,
RESUMO: Apresentaremos as práticas de escrita, em contextos escolares (por injunção professoral) e extraescolares (livres), reportadas por alunos, dos 9 aos 15 anos, no Ensino Básico (EB) em Portugal, por meio de inquérito por questionário a nível nacional. Essas práticas são expressão da vasta e dinâmica relação com a escrita (re)construída pelos sujeitos. A Didática da Escrita (DE) tem salientado, justamente, a relevância de conhecer mais aprofundadamente a relação que os indivíduos (re)constroem com ...
Tópico(s): Discourse Analysis in Language Studies
2018 - UNIVERSIDADE FEDERAL DE MINAS GERAIS | Educação em Revista
Fábio A. Abade dos Santos, Carina L. Carvalho, Maria C. Peleteiro, Sofia I. Gabriel, Rui Patrício, João Carvalho, Mónica V. Cunha, Margarida Duarte,
In the last decades, the European wild rabbit, particularly the Oryctolagus cuniculus algirus, a keystone species in the Iberian Peninsula ecosystems, declined severely, raising concerns from the wildlife authorities. The hunting calendar in Portugal limits sampling collection to a narrow window of few months annually. Nevertheless, governmental wildlife protection laws allow live rabbit sampling for population and sanitary evaluations. The aim of this study is to adjust blood collection protocols ...
Tópico(s): Leech Biology and Applications
2019 - BioOne | Wildlife Biology
Fernando Magro, Elaine F. F. da Cunha, Fernando Araújo, Elsa Meireles, Pedro L. Valls Pereira, Mário Dinis‐Ribeiro, Fernando Tavarela Veloso, Rui Medeiros, Patrício Soares‐da‐Silva,
Tópico(s): Microscopic Colitis
2006 - Springer Science+Business Media | Digestive Diseases and Sciences